The human disease database
MalaCards is an integrated database of human maladies and their annotations, modeled on the architecture and richness of the popular GeneCards database of human genes. more...
The MalaCards disease and disorders database is organized into "disease cards", each
integrating prioritized information, and listing numerous known aliases for each disease, along
with a variety of annotations, as well as inter-disease connections, empowered by the GeneCards
relational database, searches, and GeneDecks/GeneAnalytics set-analyses. Annotations include: symptoms, drugs,
articles, genes, clinical trials, related diseases/disorders and more. An automatic computational
information retrieval engine populates the disease cards, using remote data, as well as
information gleaned using the GeneCards platform to compile the disease database. The MalaCards
disease database integrates both specialized and general disease lists, including rare diseases,
genetic diseases, complex disorders and more.
MalaCards disease sections are populated by:
1) Directly interrogating disease resources, to establish integrated disease names, synonyms, summaries, drugs/therapeutics/treatments, clinical features, genetic tests, and anatomical context;
2) Searching GeneCards for related publications, and for associated genes;
3) Analyzing disease-associated gene-sets in GeneDecks/GeneAnalytics to yield affiliated pathways, phenotypes, compounds, and GO terms;
4) Searching within MalaCards itself, e.g. for additional related diseases/disorders. less...
19,811 disease entries, consolidated from 64 sources