The human disease database

MalaCards is an integrated database of human maladies and their annotations, modeled on the architecture and richness of the popular GeneCards database of human genes.  more...

The MalaCards disease and disorders database is organized into "disease cards", each integrating prioritized information, and listing numerous known aliases for each disease, along with a variety of annotations, as well as inter-disease connections, empowered by the GeneCards relational database, searches, and GeneDecks set-analyses. Annotations include: symptoms, drugs, articles, genes, clinical trials, related diseases/disorders and more. An automatic computational information retrieval engine populates the disease cards, using remote data, as well as information gleaned using the GeneCards platform to compile the disease database. The MalaCards disease database integrates both specialized and general disease lists, including rare diseases, genetic diseases, complex disorders and more.

MalaCards disease sections are populated by:
1) Directly interrogating disease resources, to establish integrated disease names, synonyms, summaries, drugs/therapeutics/treatments, clinical features, genetic tests, and anatomical context;
2) Searching GeneCards for related publications, and for associated genes;
3) Analyzing disease-associated gene-sets in GeneDecks to yield affiliated pathways, phenotypes, compounds, and GO terms;
4) Searching within MalaCards itself, e.g. for additional related diseases/disorders.   less...

19,663 disease entries, consolidated from 66 sources

We welcome your feedback

Sample Malady
View a random malady
Deafness Onychodystrophy Osteodystrophy and Mental Retardation Syndrome (MIFTS: 29)
Browse MalaCards: 1-9 | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Empowered by the GeneCards Suite
GeneCards The Human Gene CompendiumExplore sets of GeneCards genes, currently via GeneAnalytics and GenesLikeMeGenerates a file of GeneCards annotations for your list of genesPresents an integrated map for each human chromosome,  based on data integrated by the GeneLoc algorithm

In our pipeline
HPO disease phenotypes
Advanced search
Improved expression
Collaborations
News

Previous version