MCID: 3BT002
MIFTS: 14

3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal Hyperplasia malady

Endocrine diseases category

Summaries for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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MalaCards: 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal Hyperplasia is related to congenital adrenal hyperplasia and infertility. An important gene associated with 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal Hyperplasia is HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). The compounds trilostane and 17-hydroxypregnenolone have been mentioned in the context of this disorder.

Aliases & Classifications for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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Classifications:

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Anatomical: Endocrine diseases


Aliases & Descriptions:

3-beta-hydroxysteroid dehydrogenase-deficient congenital adrenal hyperplasia 20


Related Diseases for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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17GeneCards, 18GeneDecks
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Diseases related to 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal Hyperplasia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1congenital adrenal hyperplasia30.8HSD3BP4, HSD3B2
2infertility10.0HSD3BP4
3pseudohermaphroditism10.0HSD3B2
4addison's disease10.0HSD3B2
5hyperandrogenism10.0HSD3BP4, HSD3B2
6polycystic ovary syndrome10.0HSD3BP4, HSD3B2

Graphical network of diseases related to 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal Hyperplasia:



Diseases related to 3-beta-hydroxysteroid dehydrogenase-deficient congenital adrenal hyperplasia

Clinical Features for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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Drugs & Therapeutics for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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Genetic tests related to 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal Hyperplasia:

id Genetic test Affiliating Genes
1 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal Hyperplasia20 HSD3B2

Anatomical Context for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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Animal Models for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal... or affiliated genes

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Publications for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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Genetic Variations for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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Expression for genes affiliated with 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal Hyperplasia

Search GEO for disease gene expression data for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal Hyperplasia.

Pathways for genes affiliated with 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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Compounds for genes affiliated with 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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44Novoseek, 11DrugBank, 24HMDB, 49PharmGKB, 59Tocris Bioscience, 28IUPHAR
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Compounds related to 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal Hyperplasia according to GeneCards/GeneDecks:

(show all 17)
idCompoundScoreTop Affiliating Genes
1trilostane44 1110.4HSD3BP4, HSD3B2
217-hydroxypregnenolone449.4HSD3BP4, HSD3B2
317-hydroxyprogesterone44 2410.4HSD3BP4, HSD3B2
411beta-hydroxysteroid449.4HSD3BP4, HSD3B2
53beta-hydroxysteroid449.4HSD3B2, HSD3BP4
6dehydroepiandrosterone sulfate449.4HSD3BP4, HSD3B2
717beta-hydroxysteroid449.4HSD3BP4, HSD3B2
8dhea449.4HSD3BP4, HSD3B2
9androstenedione44 2410.3HSD3B2, HSD3BP4
10acth449.3HSD3BP4, HSD3B2
11nadh44 11 2411.3HSD3BP4, HSD3B2
12forskolin44 49 1111.2HSD3BP4, HSD3B2
13progesterone44 59 28 11 2413.2HSD3B2, HSD3BP4
14testosterone44 59 11 2412.1HSD3BP4, HSD3B2
15estrogen449.1HSD3BP4, HSD3B2
16cholesterol44 28 11 2412.0HSD3BP4, HSD3B2
17steroid448.8HSD3BP4, HSD3B2

GO Terms for genes affiliated with 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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Products for genes affiliated with 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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  • Antibodies
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  • Lysates
  • Antibodies

Sources for 3-Beta-Hydroxysteroid Dehydrogenase-Deficient Congenital Adrenal...

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet