MCID: 45X001
MIFTS: 15

45,x/46,xy Mixed Gonadal Dysgenesis malady

Reproductive diseases, Endocrine diseases, Fetal diseases categories

Summaries for 45,x/46,xy Mixed Gonadal Dysgenesis

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MalaCards: 45,x/46,xy Mixed Gonadal Dysgenesis, also known as 45,x0/46,xy mixed gonadal dysgenesis, is related to gonadal dysgenesis and mixed gonadal dysgenesis. An important gene associated with 45,x/46,xy Mixed Gonadal Dysgenesis is SRY (sex determining region Y).

Aliases & Classifications for 45,x/46,xy Mixed Gonadal Dysgenesis

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48Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases
Anatomical: Reproductive diseases, Endocrine diseases


Characteristics (Orphanet epidemiological data):

48
45,x0/46,xy mixed gonadal dysgenesis:
Inheritance: Sporadic; Age of onset: Adolescence / Young adulthood; Age of death: Normal


Aliases & Descriptions:

45,x/46,xy mixed gonadal dysgenesis 48
45,x0/46,xy mixed gonadal dysgenesis 48
45,x0/46,xy mgd 48
45,x/46,xy mgd 48


External Ids:

ICD10 via Orphanet26 Q98.7

Related Diseases for 45,x/46,xy Mixed Gonadal Dysgenesis

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17GeneCards, 18GeneDecks
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Diseases in the Mixed Gonadal Dysgenesis family:

45,x/46,xy mixed gonadal dysgenesis

Diseases related to 45,x/46,xy Mixed Gonadal Dysgenesis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1gonadal dysgenesis30.8SRY
2mixed gonadal dysgenesis10.5
3turner syndrome10.0TSPY1
4luteoma10.0SRY
5swyer syndrome10.0SRY
6male infertility10.0TSPY1
7infertility10.0SRY
8gonadoblastoma10.0SRY, TSPY1
9dysgerminoma10.0TSPY1, SRY
10azoospermia10.0SRY, TSPY1

Graphical network of diseases related to 45,x/46,xy Mixed Gonadal Dysgenesis:



Diseases related to 45,x/46,xy mixed gonadal dysgenesis

Clinical Features for 45,x/46,xy Mixed Gonadal Dysgenesis

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Drugs & Therapeutics for 45,x/46,xy Mixed Gonadal Dysgenesis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for 45,x/46,xy Mixed Gonadal Dysgenesis

Drug clinical trials:

Search ClinicalTrials for 45,x/46,xy Mixed Gonadal Dysgenesis

Search NIH Clinical Center for 45,x/46,xy Mixed Gonadal Dysgenesis

Search CenterWatch for 45,x/46,xy Mixed Gonadal Dysgenesis

Genetic Tests for 45,x/46,xy Mixed Gonadal Dysgenesis

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Anatomical Context for 45,x/46,xy Mixed Gonadal Dysgenesis

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Animal Models for 45,x/46,xy Mixed Gonadal Dysgenesis or affiliated genes

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Publications for 45,x/46,xy Mixed Gonadal Dysgenesis

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Genetic Variations for 45,x/46,xy Mixed Gonadal Dysgenesis

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Expression for genes affiliated with 45,x/46,xy Mixed Gonadal Dysgenesis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with 45,x/46,xy Mixed Gonadal Dysgenesis

Search GEO for disease gene expression data for 45,x/46,xy Mixed Gonadal Dysgenesis.

Pathways for genes affiliated with 45,x/46,xy Mixed Gonadal Dysgenesis

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Compounds for genes affiliated with 45,x/46,xy Mixed Gonadal Dysgenesis

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GO Terms for genes affiliated with 45,x/46,xy Mixed Gonadal Dysgenesis

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16Gene Ontology
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Biological processes related to 45,x/46,xy Mixed Gonadal Dysgenesis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell differentiationGO:0301549.1TSPY1, SRY

Products for genes affiliated with 45,x/46,xy Mixed Gonadal Dysgenesis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for 45,x/46,xy Mixed Gonadal Dysgenesis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet