MCID: ABD010
MIFTS: 39

Abdominal Wall Defect malady

Gastrointestinal diseases, Endocrine diseases categories
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Summaries for Abdominal Wall Defect

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Genetics Home Reference:21 An abdominal wall defect is an opening in the abdomen through which various abdominal organs can protrude. This opening varies in size and can usually be diagnosed early in fetal development, typically between the tenth and fourteenth weeks of pregnancy. There are two main types of abdominal wall defects: omphalocele and gastroschisis. Omphalocele is an opening in the center of the abdominal wall where the umbilical cord meets the abdomen. Organs (typically the intestines, stomach, and liver) protrude through the opening into the umbilical cord and are covered by the same protective membrane that covers the umbilical cord. Gastroschisis is a defect in the abdominal wall, usually to the right of the umbilical cord, through which the large and small intestines protrude (although other organs may sometimes bulge out). There is no membrane covering the exposed organs in gastroschisis.

MalaCards based summary: Abdominal Wall Defect, also known as thyroid hormone plasma membrane transport defect, is related to gastroschisis and omphalocele. An important gene associated with Abdominal Wall Defect is CDKN1C (cyclin-dependent kinase inhibitor 1C (p57, Kip2)). The compound irinotecan have been mentioned in the context of this disorder. Affiliated tissues include small intestine, liver and thyroid, and related mouse phenotypes are behavior/neurological and reproductive system.

Wikipedia:65 Abdominal Wall defects are a type of congenital defect that allows the stomach, the intestines, or other... more...

Aliases & Classifications for Abdominal Wall Defect

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Related Diseases for Abdominal Wall Defect

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Graphical network of the top 20 diseases related to Abdominal Wall Defect:



Diseases related to abdominal wall defect

Symptoms for Abdominal Wall Defect

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Drugs & Therapeutics for Abdominal Wall Defect

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Drug clinical trials:

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Search NIH Clinical Center for Abdominal Wall Defect

Genetic Tests for Abdominal Wall Defect

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Anatomical Context for Abdominal Wall Defect

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MalaCards organs/tissues related to Abdominal Wall Defect:

32
Small intestine, Liver, Thyroid, Skin

Animal Models for Abdominal Wall Defect or affiliated genes

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MGI Mouse Phenotypes related to Abdominal Wall Defect:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.6CDKN1C, ACHE, AFP
2MP:00053898.3AFP, ACHE, CDKN1C
3MP:00107687.9CDKN1C, ACHE, NSD1, AFP

Publications for Abdominal Wall Defect

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Articles related to Abdominal Wall Defect:

(show top 50)    (show all 123)
idTitleAuthorsYear
1
Full thickness abdominal wall defect in growing rats as a model for congenital diaphragmatic hernia prosthetic repair. (25280646)
2014
2
Carbon nanotubes as VEGF carriers to improve the early vascularization of porcine small intestinal submucosa in abdominal wall defect repair. (24648727)
2014
3
Investigating muscle regeneration with a dermis/small intestinal submucosa scaffold in a rat full-thickness abdominal wall defect model. (24889422)
2014
4
Effect of copaiba oil on correction of abdominal wall defect treated with the use of polypropylene/polyglecaprone mesh. (23370927)
2013
5
Use of a pre-expanded "propeller" deep inferior epigastric perforator (DIEP) flap for a large abdominal wall defect. (23031631)
2013
6
Spontaneous intraamniotic hemorrhage in the second trimester mimicking an abdominal wall defect. (24592085)
2013
7
Abdominal wall defect with large duodenal disruption treated by a free tissue flap with a help of temporary expandable metallic stent. (24266016)
2013
8
Abdominal wall defect repair with biological prosthesis in transplanted patients: single center retrospective analysis and review of the literature. (23636834)
2013
9
Is muscular atrophy a contraindication in laparoscopic abdominal wall defect repair? A prospective study. (22369826)
2012
10
Effects of collagen prosthesis cross-linking on long-term tissue regeneration following the repair of an abdominal wall defect. (22564232)
2012
11
Management of anterior abdominal wall defect using a pedicled tensor fascia lata flap: a case report. (23304156)
2012
12
The use of biological mesh to repair one large, contaminated abdominal wall defect due to neoplastic invasion. Report of a case. (22462340)
2012
13
First-trimester two-dimensional and three-dimensional ultrasound demonstration of craniofacial defects, abdominal wall defects and upper limb deficiency associated with limb-body wall complex. (22212340)
2011
14
Left-sided congenital abdominal wall defect and intestinal malformation--a rare case. (23008980)
2011
15
Comparison of Surgisis, AlloDerm, and Vicryl Woven Mesh grafts for abdominal wall defect repair in an animal model. (19967358)
2010
16
Spontaneous sutureless closure of the abdominal wall defect in gastroschisis using a commercial wound retractor system. (19705131)
2009
17
New technical approach for the repair of an abdominal wall defect after a transverse rectus abdominis myocutaneous flap: a case report. (18416835)
2008
18
Acellular dermal matrix in the management of contaminated abdominal wall defects following primary actinomycosis excision. (18667371)
2008
19
Repair of a full-thickness abdominal wall defect with an innervated latissimus dorsi free flap. (17486522)
2007
20
Reconstruction of an abdominal wall defect following wide excision of metastatic squamous cell carcinoma at the percutaneous gastrostomy site in a head and neck cancer patient. (19554114)
2006
21
The sandwich omental flap for abdominal wall defect reconstruction. (16086992)
2005
22
Homologous muscle acellular matrix seeded with autologous myoblasts as a tissue-engineering approach to abdominal wall-defect repair. (15585259)
2005
23
Repair of an abdominal wall defect after a salvage laparotomy for sepsis. (14759790)
2004
24
Neurovascular latissimus dorsi free-flap transfer for reconstruction of a major abdominal-wall defect in a 13-month-old child: late follow-up. (15088208)
2004
25
Morbidity and mortality of short-bowel syndrome in infants with abdominal wall defects. (12467323)
2002
26
Morbidity and quality of life in adult patients with a congenital abdominal wall defect: a questionnaire survey. (12407546)
2002
27
Abdominal wall defect and enterocutaneous fistula treatment with the Vacuum-Assisted Closure (V.A.C.) system. (11743402)
2001
28
Exstrophic abdominal wall defect without bladder exstrophy (pseudo-exstrophy) (9634060)
1998
29
Reconstruction of a large abdominal wall defect using combined free tensor fasciae latae musculocutaneous flap and anterolateral thigh flap. (9811028)
1998
30
Changing ultrasonographic appearance of a vesico-allantoic abdominal wall defect. (7673458)
1995
31
Anal atresia and abdominal wall defect as unusual symptoms in EEC syndrome. (7546455)
1995
32
Gastroesophageal reflux in neonates with congenital abdominal wall defect. (8773221)
1995
33
The use of a human dura mater allograft for the repair of a contaminated abdominal wall defect: report of a case. (8054821)
1994
34
Gastroschisis followed by absorption of the small bowel and closure of the abdominal wall defect. (7933050)
1994
35
Re: Secondary reconstruction of abdominal wall defects associated with exstrophy of the bladder. (7857058)
1994
36
Bursting strength evaluation. Comparison of 0-Prolene sutures and endoscopic staples in an experimental prosthetic patch repair of abdominal wall defect. (7974115)
1994
37
A comparison of amniotic fluid alpha-fetoprotein and acetylcholinesterase in the prenatal diagnosis of open neural tube defects and anterior abdominal wall defects. (7681980)
1993
38
Secondary reconstruction of abdominal wall defects associated with exstrophy of the bladder. (8285533)
1993
39
Psychosocial adjustment and physical growth in children with imperforate anus or abdominal wall defects. (1834823)
1991
40
X-linked ichthyosis and congenital abdominal wall defects. (1825203)
1991
41
Transporting the infant with an abdominal wall defect. (2144036)
1990
42
Prenatal sonographic diagnosis of a vesico-allantoic abdominal wall defect. (2521673)
1989
43
The abdominal wall defect "almost always" lies to the right of the umbilicus. (2976820)
1988
44
Use of polypropylene mesh for abdominal wall defect in surgery of advanced urachus carcinoma. (2968703)
1988
45
Abdominal wall defects: omphalocele and gastroschisis (continuing education credit). (2961975)
1987
46
The fetus with an abdominal wall defect: management and outcome. (2953877)
1987
47
Reconstruction of a large lateral abdominal wall defect with an ilio-lumbar bi-pedicled flap. (6234961)
1984
48
Congenital abdominal wall defects: gastroschisis and omphalocele. (6211335)
1982
49
Management of enterocutaneous fistulas and problem stomas with silicone casting of the abdominal wall defect. (145809)
1977
50
A method of closure of the abdominal wall defect in exstrophy of the bladder. (13327152)
1956

Variations for Abdominal Wall Defect

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Expression for genes affiliated with Abdominal Wall Defect

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Expression patterns in normal tissues for genes affiliated with Abdominal Wall Defect

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Pathways for genes affiliated with Abdominal Wall Defect

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Compounds for genes affiliated with Abdominal Wall Defect

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Sources:
44Novoseek, 50PharmGKB, 11DrugBank
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Compounds related to Abdominal Wall Defect according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1irinotecan44 50 1111.1ACHE, AFP

GO Terms for genes affiliated with Abdominal Wall Defect

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Biological processes related to Abdominal Wall Defect according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of transcription, DNA-templatedGO:0458939.3CDKN1C, NSD1

Products for genes affiliated with Abdominal Wall Defect

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  • Antibodies
  • Proteins
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Sources for Abdominal Wall Defect

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet