MCID: ABD010
MIFTS: 37

Abdominal Wall Defect malady

Gastrointestinal diseases, Endocrine diseases categories

Summaries for Abdominal Wall Defect

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22Genetics Home Reference, 66Wikipedia, 34MalaCards
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Genetics Home Reference:22 An abdominal wall defect is an opening in the abdomen through which various abdominal organs can protrude. This opening varies in size and can usually be diagnosed early in fetal development, typically between the tenth and fourteenth weeks of pregnancy. There are two main types of abdominal wall defects: omphalocele and gastroschisis. Omphalocele is an opening in the center of the abdominal wall where the umbilical cord meets the abdomen. Organs (typically the intestines, stomach, and liver) protrude through the opening into the umbilical cord and are covered by the same protective membrane that covers the umbilical cord. Gastroschisis is a defect in the abdominal wall, usually to the right of the umbilical cord, through which the large and small intestines protrude (although other organs may sometimes bulge out). There is no membrane covering the exposed organs in gastroschisis.

MalaCards: Abdominal Wall Defect, also known as thyroid hormone plasma membrane transport defect, is related to gastroschisis and omphalocele. An important gene associated with Abdominal Wall Defect is CDKN1C (cyclin-dependent kinase inhibitor 1C (p57, Kip2)). The compound irinotecan have been mentioned in the context of this disorder. Affiliated tissues include thyroid, liver and skin, and related mouse phenotypes are behavior/neurological and reproductive system.

Wikipedia:66 Abdominal Wall defects are a type of congenital defect that allows the stomach, the intestines, or other... more...

Aliases & Classifications for Abdominal Wall Defect

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63UMLS, 22Genetics Home Reference, 26ICD10
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Related Diseases for Abdominal Wall Defect

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Abdominal Wall Defect:



Diseases related to abdominal wall defect

Symptoms for Abdominal Wall Defect

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Drugs & Therapeutics for Abdominal Wall Defect

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Abdominal Wall Defect

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Anatomical Context for Abdominal Wall Defect

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34MalaCards
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MalaCards organs/tissues related to Abdominal Wall Defect:

34
Thyroid, Liver, Skin

Animal Models for Abdominal Wall Defect or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Abdominal Wall Defect:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.6CDKN1C, ACHE, AFP
2MP:00053898.3CDKN1C, AFP, ACHE
3MP:00107687.9NSD1, AFP, CDKN1C, ACHE

Publications for Abdominal Wall Defect

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53PubMed
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Articles related to Abdominal Wall Defect:

(show top 50)    (show all 115)
idTitleAuthorsYear
1
Effect of copaiba oil on correction of abdominal wall defect treated with the use of polypropylene/polyglecaprone mesh. (23370927)
2013
2
Use of a pre-expanded "propeller" deep inferior epigastric perforator (DIEP) flap for a large abdominal wall defect. (23031631)
2013
3
Abdominal wall defect with large duodenal disruption treated by a free tissue flap with a help of temporary expandable metallic stent. (24266016)
2013
4
Abdominal wall defect repair with biological prosthesis in transplanted patients: single center retrospective analysis and review of the literature. (23636834)
2013
5
Is muscular atrophy a contraindication in laparoscopic abdominal wall defect repair? A prospective study. (22369826)
2012
6
Effects of collagen prosthesis cross-linking on long-term tissue regeneration following the repair of an abdominal wall defect. (22564232)
2012
7
Management of anterior abdominal wall defect using a pedicled tensor fascia lata flap: a case report. (23304156)
2012
8
The use of biological mesh to repair one large, contaminated abdominal wall defect due to neoplastic invasion. Report of a case. (22462340)
2012
9
First-trimester two-dimensional and three-dimensional ultrasound demonstration of craniofacial defects, abdominal wall defects and upper limb deficiency associated with limb-body wall complex. (22212340)
2011
10
Left-sided congenital abdominal wall defect and intestinal malformation--a rare case. (23008980)
2011
11
Comparison of Surgisis, AlloDerm, and Vicryl Woven Mesh grafts for abdominal wall defect repair in an animal model. (19967358)
2010
12
Spontaneous sutureless closure of the abdominal wall defect in gastroschisis using a commercial wound retractor system. (19705131)
2009
13
New technical approach for the repair of an abdominal wall defect after a transverse rectus abdominis myocutaneous flap: a case report. (18416835)
2008
14
Acellular dermal matrix in the management of contaminated abdominal wall defects following primary actinomycosis excision. (18667371)
2008
15
Repair of a full-thickness abdominal wall defect with an innervated latissimus dorsi free flap. (17486522)
2007
16
Reconstruction of an abdominal wall defect following wide excision of metastatic squamous cell carcinoma at the percutaneous gastrostomy site in a head and neck cancer patient. (19554114)
2006
17
The sandwich omental flap for abdominal wall defect reconstruction. (16086992)
2005
18
Homologous muscle acellular matrix seeded with autologous myoblasts as a tissue-engineering approach to abdominal wall-defect repair. (15585259)
2005
19
Repair of an abdominal wall defect after a salvage laparotomy for sepsis. (14759790)
2004
20
Neurovascular latissimus dorsi free-flap transfer for reconstruction of a major abdominal-wall defect in a 13-month-old child: late follow-up. (15088208)
2004
21
Unusual congenital abdominal wall defect and review. (12749066)
2003
22
Morbidity and mortality of short-bowel syndrome in infants with abdominal wall defects. (12467323)
2002
23
Morbidity and quality of life in adult patients with a congenital abdominal wall defect: a questionnaire survey. (12407546)
2002
24
Abdominal wall defect and enterocutaneous fistula treatment with the Vacuum-Assisted Closure (V.A.C.) system. (11743402)
2001
25
Exstrophic abdominal wall defect without bladder exstrophy (pseudo-exstrophy) (9634060)
1998
26
Reconstruction of a large abdominal wall defect using combined free tensor fasciae latae musculocutaneous flap and anterolateral thigh flap. (9811028)
1998
27
Changing ultrasonographic appearance of a vesico-allantoic abdominal wall defect. (7673458)
1995
28
Anal atresia and abdominal wall defect as unusual symptoms in EEC syndrome. (7546455)
1995
29
Gastroesophageal reflux in neonates with congenital abdominal wall defect. (8773221)
1995
30
The use of a human dura mater allograft for the repair of a contaminated abdominal wall defect: report of a case. (8054821)
1994
31
Gastroschisis followed by absorption of the small bowel and closure of the abdominal wall defect. (7933050)
1994
32
Re: Secondary reconstruction of abdominal wall defects associated with exstrophy of the bladder. (7857058)
1994
33
Bursting strength evaluation. Comparison of 0-Prolene sutures and endoscopic staples in an experimental prosthetic patch repair of abdominal wall defect. (7974115)
1994
34
A comparison of amniotic fluid alpha-fetoprotein and acetylcholinesterase in the prenatal diagnosis of open neural tube defects and anterior abdominal wall defects. (7681980)
1993
35
Secondary reconstruction of abdominal wall defects associated with exstrophy of the bladder. (8285533)
1993
36
Torque deformation sequence associated with short umbilical cord and abdominal wall defect. (8280884)
1993
37
Rapid prenatal diagnosis of Patau's syndrome in a fetus with an abdominal wall defect by 72 hour culture of cells from amniotic fluid. (8309903)
1993
38
Psychosocial adjustment and physical growth in children with imperforate anus or abdominal wall defects. (1834823)
1991
39
X-linked ichthyosis and congenital abdominal wall defects. (1825203)
1991
40
Transporting the infant with an abdominal wall defect. (2144036)
1990
41
Abdominal wall defect with liver appendage. (2530330)
1989
42
Prenatal sonographic diagnosis of a vesico-allantoic abdominal wall defect. (2521673)
1989
43
The abdominal wall defect "almost always" lies to the right of the umbilicus. (2976820)
1988
44
Use of polypropylene mesh for abdominal wall defect in surgery of advanced urachus carcinoma. (2968703)
1988
45
Abdominal wall defects: omphalocele and gastroschisis (continuing education credit). (2961975)
1987
46
The fetus with an abdominal wall defect: management and outcome. (2953877)
1987
47
Reconstruction of a large lateral abdominal wall defect with an ilio-lumbar bi-pedicled flap. (6234961)
1984
48
Congenital abdominal wall defects: gastroschisis and omphalocele. (6211335)
1982
49
Management of enterocutaneous fistulas and problem stomas with silicone casting of the abdominal wall defect. (145809)
1977
50
A method of closure of the abdominal wall defect in exstrophy of the bladder. (13327152)
1956

Variations for Abdominal Wall Defect

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Expression for genes affiliated with Abdominal Wall Defect

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Abdominal Wall Defect

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Pathways for genes affiliated with Abdominal Wall Defect

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Compounds for genes affiliated with Abdominal Wall Defect

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46Novoseek, 52PharmGKB, 12DrugBank
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Compounds related to Abdominal Wall Defect according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1irinotecan46 52 1211.1ACHE, AFP

GO Terms for genes affiliated with Abdominal Wall Defect

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17Gene Ontology
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Biological processes related to Abdominal Wall Defect according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of transcription, DNA-templatedGO:0458939.3CDKN1C, NSD1

Products for genes affiliated with Abdominal Wall Defect

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Sources for Abdominal Wall Defect

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet