MCID: ACN019
MIFTS: 29

Acanthamoeba Keratitis malady

Infectious diseases, Rare diseases categories

Aliases & Classifications for Acanthamoeba Keratitis

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Sources:
47Orphanet, 34MESH via Orphanet, 26ICD10 via Orphanet, 61UMLS via Orphanet
See all sources

Acanthamoeba Keratitis, Aliases & Descriptions:

Name: Acanthamoeba Keratitis 47


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases, Rare diseases


Characteristics (Orphanet epidemiological data):

47
acanthamoeba keratitis:
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: All ages; Age of death: normal life expectancy


External Ids:

Orphanet47 67043
MESH via Orphanet34 D015823
ICD10 via Orphanet26 B60.1+, H19.2*
UMLS via Orphanet61 C0000880

Summaries for Acanthamoeba Keratitis

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Wikipedia:63 Acanthamoeba keratitis is a rare disease in which amoebae invade the cornea of the eye. It may result in... more...

MalaCards based summary: Acanthamoeba Keratitis is related to keratitis and cataract. An important gene associated with Acanthamoeba Keratitis is MBL2 (mannose-binding lectin (protein C) 2, soluble). The compounds rantes and ethanol have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and testes.

Related Diseases for Acanthamoeba Keratitis

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Diseases related to Acanthamoeba Keratitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 21)
idRelated DiseaseScoreTop Affiliating Genes
1keratitis11.5
2cataract10.4
3dacryoadenitis10.3
4herpes simplex10.3
5keratoconjunctivitis10.3
6pulmonary hypertension10.2
7keratoconus10.2
8keratopathy10.2
9chronic fatigue syndrome10.2
10trachoma10.2
11sympathetic ophthalmia10.2
12chorioretinitis10.2
13corneal neovascularization10.2
14endophthalmitis10.2
15myopia10.2
16plague10.2
17uncombable hair syndrome10.2
18blindness10.2
19leukemia9.9CXCL2, MBL2
20pneumonia9.8CXCL2, MBL2
21viral infectious disease9.7CXCL2, MBL2

Graphical network of the top 20 diseases related to Acanthamoeba Keratitis:



Diseases related to acanthamoeba keratitis

Symptoms for Acanthamoeba Keratitis

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Drugs & Therapeutics for Acanthamoeba Keratitis

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Drug clinical trials:

Search ClinicalTrials for Acanthamoeba Keratitis

Search NIH Clinical Center for Acanthamoeba Keratitis

Genetic Tests for Acanthamoeba Keratitis

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Anatomical Context for Acanthamoeba Keratitis

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MalaCards organs/tissues related to Acanthamoeba Keratitis:

31
Eye, Retina, Testes

Animal Models for Acanthamoeba Keratitis or affiliated genes

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Publications for Acanthamoeba Keratitis

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Articles related to Acanthamoeba Keratitis:

(show top 50)    (show all 453)
idTitleAuthorsYear
1
Contact Lens-Related Acanthamoeba Keratitis and Accompanying Dacryoadenitis. (25603441)
2015
2
Acanthamoeba keratitis: a new normal. (25012982)
2014
3
Acanthamoeba keratitis: study of the 5-year incidence in Israel. (23878134)
2013
4
Bowman's layer encystment in cases of persistent Acanthamoeba keratitis. (22927735)
2012
5
Radial keratoneuritis as a presenting sign in acanthamoeba keratitis. (21887085)
2011
6
Acanthamoeba keratitis--a diagnostic challenge. (22288216)
2011
7
Toll-like receptor 4 signalling pathway activation in a rat model of Acanthamoeba Keratitis. (21155840)
2011
8
Clinical experience with Acanthamoeba keratitis at the cole eye institute, 1999-2008. (20539213)
2010
9
Acanthamoeba keratitis cluster: an increase in Acanthamoeba keratitis in Australia. (19723126)
2009
10
Contact lens-related acanthamoeba keratitis. (19741556)
2009
11
Painless Acanthamoeba keratitis in a soft contact lens wearer--case report. (19860131)
2009
12
Fusarium and Acanthamoeba keratitis: can a single centre detect outbreaks? (18441185)
2008
13
Acanthamoeba keratitis associated with cosmetic contact lens wear. (19098954)
2008
14
The application of in vivo confocal scanning laser microscopy in the management of Acanthamoeba keratitis. (17679934)
2007
15
Good visual outcome after prompt treatment of acanthamoeba keratitis associated with overnight orthokeratology lens wear. (17993830)
2007
16
Acanthamoeba keratitis related to cosmetic contact lenses. (17997788)
2007
17
Acanthamoeba keratitis. (17157149)
2006
18
Epidemiological characteristics of a Chicago-area Acanthamoeba keratitis outbreak. (16876498)
2006
19
Six-year review of Acanthamoeba keratitis in New South Wales, Australia: 1997-2002. (15670077)
2005
20
Heidelberg retina tomograph II findings of Acanthamoeba keratitis. (16321898)
2005
21
Impression cytology in the diagnosis of acanthamoeba keratitis with surface involvement. (14962424)
2004
22
Acanthamoeba keratitis in non-contact lens wearers in India: DNA typing-based validation and a simple detection assay. (15477452)
2004
23
Acanthamoeba keratitis: the role of domestic tap water contamination in the United Kingdom. (14691169)
2004
24
Delay in diagnosis and outcome of Acanthamoeba keratitis. (15221303)
2004
25
Arthrographis keratitis mimicking acanthamoeba keratitis. (15084869)
2004
26
Non-contact lens related Acanthamoeba keratitis at a tertiary eye care center in south India: Implications for eye care programs in the region. (12709670)
2003
27
Recent advances in the treatment of Acanthamoeba keratitis. (12145728)
2002
28
Persistence of acanthamoeba antigen following acanthamoeba keratitis. (11222330)
2001
29
Evaluation of immunoperoxidase staining technique in the diagnosis of Acanthamoeba keratitis. (15887727)
2001
30
Laser in situ Keratomileusis Following Acanthamoeba Keratitis. (24364509)
2000
31
Patient characteristics, diagnosis, and treatment of non-contact lens related Acanthamoeba keratitis. (11004092)
2000
32
An epidemic of presumed Acanthamoeba keratitis that followed regional flooding. Results of a case-control investigation. (9715690)
1998
33
Acanthamoeba keratitis with symbiosis of Hartmannella ameba. (9625566)
1998
34
Successful medical treatment of Acanthamoeba keratitis. (9700010)
1997-1998
35
Acanthamoeba keratitis and contact lens wear. (9371196)
1997
36
Should we be using polyhexamethylene biguanide to treat Acanthamoeba keratitis? (9267593)
1997
37
Acanthamoeba keratitis: is water exposure a true risk factor? (9001773)
1997
38
Confocal microscopy findings of Acanthamoeba keratitis. (8623881)
1996
39
Successful medical therapy of Acanthamoeba keratitis with topical chlorhexidine and propamidine. (8944089)
1996
40
Chemotherapy for acanthamoeba keratitis. (7891502)
1995
41
Acanthamoeba keratitis: experience in a non-specialist microbiology laboratory. (1890209)
1991
42
Acanthamoeba keratitis. (1710209)
1991
43
Examination of hydrophilic contact lenses with light microscopy to aid in the diagnosis of Acanthamoeba keratitis. (2774043)
1989
44
Radial intrastromal lines in Acanthamoeba keratitis. Case report. (3390046)
1988
45
Elevated corneal epithelial lines in Acanthamoeba keratitis. (3046583)
1988
46
Acanthamoeba keratitis. Potential role for topical clotrimazole in combination chemotherapy. (3046582)
1988
47
Acanthamoeba keratitis. (3307898)
1987
48
Diagnosis and management of Acanthamoeba keratitis. (4037025)
1985
49
Acanthamoeba keratitis successfully treated medically. (4052364)
1985
50
Management of Acanthamoeba keratitis. A case report and review of the literature. (6093021)
1984

Variations for Acanthamoeba Keratitis

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Expression for genes affiliated with Acanthamoeba Keratitis

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Search GEO for disease gene expression data for Acanthamoeba Keratitis.

Pathways for genes affiliated with Acanthamoeba Keratitis

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Compounds for genes affiliated with Acanthamoeba Keratitis

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Sources:
43Novoseek, 49PharmGKB, 24HMDB, 12DrugBank, 28IUPHAR
See all sources

Compounds related to Acanthamoeba Keratitis according to GeneCards Suite gene sharing:

(show all 11)
idCompoundScoreTop Affiliating Genes
1rantes439.4MBL2, CXCL2
2ethanol43 49 24 1212.4MBL2, CXCL2
3fibrinogen439.3CXCL2, MBL2
4dexamethasone43 49 28 1212.3MBL2, CXCL2
5vegf439.3MBL2, CXCL2
6nitric oxide43 24 1211.2CXCL2, MBL2
7oxygen43 2410.2MBL2, CXCL2
8estrogen439.1MBL2, CXCL2
9tyrosine439.1MBL2, CXCL2
10lipid439.0CXCL2, MBL2
11serine438.8MBL2, CXCL2

GO Terms for genes affiliated with Acanthamoeba Keratitis

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Cellular components related to Acanthamoeba Keratitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055769.1MBL2, CXCL2
2extracellular spaceGO:00056158.8MBL2, CXCL2

Products for genes affiliated with Acanthamoeba Keratitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Acanthamoeba Keratitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet