MCID: ACN010
MIFTS: 28

Acanthoma malady

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Acanthoma

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Aliases & Descriptions for Acanthoma:

Name: Acanthoma 10 45 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:174
MeSH36 D049309
NCIt42 C7419
UMLS65 C0846967

Summaries for Acanthoma

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NIH Rare Diseases:45 An acanthoma is a small, reddish bump that usually develops on the skin of an older adult.  there are several types of acanthoma, including "acantholytic", "epidermolytic", "clear cell", and "melanoacanthoma".  though most individuals have only one acanthoma, there have been rare reports of individuals who have developed many.  the exact cause of acanthoma is not known; it is sometimes called a benign tumor, and sometimes described as the result of inflammation.  acanthomas are not considered dangerous and do not require treatment, but they may be removed for cosmetic reasons or to relieve any associated symptoms. last updated: 3/26/2012

MalaCards based summary: Acanthoma is related to acantholytic acanthoma and clear cell acanthoma, and has symptoms including leser-trélat sign An important gene associated with Acanthoma is FGFR2 (Fibroblast Growth Factor Receptor 2). Affiliated tissues include skin, breast and lung.

Wikipedia:68 An acanthoma is a skin neoplasm composed of squamous or epidermal cells. It is located in the prickle... more...

Related Diseases for Acanthoma

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Diseases related to Acanthoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
idRelated DiseaseScoreTop Affiliating Genes
1acantholytic acanthoma32.0KRT1, KRT10, KRT9
2clear cell acanthoma12.3
3epidermolytic acanthoma12.2
4large cell acanthoma12.2
5pilar sheath acanthoma12.2
6onychocytic matricoma11.1
7keratosis10.2
8psoriasis10.1
9muir-torre syndrome9.9
10epidermodysplasia verruciformis9.9
11cellulitis9.9
12adenoiditis9.8
13basal cell carcinoma9.8
14papilloma9.8
15endometriosis9.8
16keratoacanthoma9.8
17porokeratosis9.8
18inverted follicular keratosis9.8
19molluscum contagiosum9.8
20trichofolliculoma9.8
21warty dyskeratoma9.8
22frontotemporal lobar degeneration with ubiquitin-positive inclusions9.8KRT1, KRT10
23epilepsy benign neonatal dominant form9.8KRT1, KRT10
24vulvar clear cell hidradenocarcinoma9.7KRT1, KRT10
25palmoplantar keratoderma, nonepidermolytic9.7KRT1, KRT9
26white sponge nevus 19.7KRT1, KRT9
27skin pilomatrix carcinoma9.7KRT1, KRT10
28bowenoid papulosis9.6KRT1, KRT10
29colorectal adenomatous polyposis, autosomal recessive, with pilomatricomas9.6KRT1, KRT10
30keratosis palmoplantaris striata iii9.6KRT1, KRT9
31endocrine gland cancer9.5KRT1, KRT10
32retinitis pigmentosa 309.4KRT1, KRT10
33inappropriate adh syndrome9.4KRT1, KRT9
34ichthyosis histrix, curth-macklin type9.3KRT1, KRT10, KRT9
35retinal cancer9.3KRT1, KRT10
36palmoplantar keratoderma, epidermolytic9.3KRT1, KRT10, KRT9
37epidermolysis bullosa simplex, dowling-meara type9.2KRT1, KRT10, KRT9
38ichthyosis, cyclic, with epidermolytic hyperkeratosis9.2KRT1, KRT10, KRT9
39benign eccrine breast spiradenoma9.2KRT1, KRT10, KRT9
40small intestine lymphoma9.2KRT1, KRT10, KRT9
41drug psychosis8.3FGFR2, HPD, KRT1, KRT10, KRT9

Graphical network of the top 20 diseases related to Acanthoma:



Diseases related to acanthoma

Symptoms for Acanthoma

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UMLS symptoms related to Acanthoma:


leser-trélat sign

Drugs & Therapeutics for Acanthoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Acanthoma

Genetic Tests for Acanthoma

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Anatomical Context for Acanthoma

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MalaCards organs/tissues related to Acanthoma:

33
Skin, Breast, Lung, Thyroid, T cells, Heart, Pituitary

Animal Models for Acanthoma or affiliated genes

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Publications for Acanthoma

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Articles related to Acanthoma:

(show top 50)    (show all 212)
idTitleAuthorsYear
1
Clinicopathological and dermoscopic features of angio-eccrine hyperplasia in clear cell acanthoma. (27185430)
2016
2
Case of isolated epidermolytic acanthoma: Genetic and immunohistochemical analysis. (26945829)
2016
3
A Case of Multiple Epidermolytic Acanthoma of the Scrotum: Is the Human Papillomavirus a Culprit? (26512188)
2015
4
Pigmented clear cell acanthoma of the finger simulating pigmented nevus. (25267214)
2014
5
Multiple clear cell acanthoma associated with multiple Bowen's disease. (24898560)
2014
6
Fast-growing 'giant' clear cell acanthoma detected by dermoscopy during treatment with infliximab in a psoriatic patient. (24750337)
2014
7
Multiple pigmented clear cell acanthoma in an African patient. (25414053)
2014
8
An unusual location of a pilar sheath acanthoma. (25368479)
2014
9
Dermoscopic features of clear cell acanthoma: five new cases and a review of existing published cases. (25495637)
2014
10
Clear cell acanthoma of the areola and nipple: clinical, histopathological, and immunohistochemical features of two Brazilian cases. (23539008)
2013
11
Clear cell acanthoma induced by a dermatofibroma. (23122021)
2012
12
Isolated epidermolytic acanthoma in a renal transplant recipient. (21909223)
2011
13
Hemosiderotic clear-cell acanthoma: a pigmented mimicker. (21965855)
2011
14
Eccrine syringofibroadenoma and clear cell acanthoma: an association by chance? (21252636)
2011
15
Solitary epidermolytic acanthoma: a clinical and histopathological study. (20553361)
2011
16
Clear cell acanthoma: a rare clinical diagnosis prior to biopsy. (20931670)
2010
17
Granular parakeratotic acanthoma is not adenoid seborrheic keratosis. (18496439)
2008
18
A glistening brown nodule. Pigmented clear cell acanthoma. (17310007)
2007
19
Changes of epidermodysplasia verruciformis in benign skin lesions: the EV acanthoma. (17214854)
2007
20
Expression of keratinocyte growth factor and its receptor in clear cell acanthoma. (16984257)
2006
21
Clear cell acanthoma successfully treated with a carbon dioxide laser. (16188196)
2005
22
Polypoid clear cell acanthoma of unusual size. (11174404)
2001
23
Polypoid clear cell acanthoma: case report. (11444278)
2000
24
Immunohistopathologic characterization of a dermal melanocytoma-acanthoma in a German Shepherd Dog. (10810992)
2000
25
Epidermolytic acanthomas: clinical characteristics and immunohistochemical features. (9185908)
1997
26
Immunohistochemical characterization of keratin expression in clear cell acanthoma. (7547383)
1995
27
Disseminated epidermolytic acanthoma with disseminated superficial porokeratosis and verruca vulgaris in an immunosuppressed patient. (8537558)
1995
28
Large-cell acanthoma of the skin. A study by image analysis cytometry and immunohistochemistry. (8030765)
1994
29
Etretinate therapy of solar-related kerato acanthoma. (8240190)
1993
30
Melanocytes in clear cell acanthoma. (1928630)
1991
31
Immunohistochemical detection of calmodulin. A contribution to the histogenetic classification of eccrine poroma and clear cell acanthoma]. (2172054)
1990
32
Achromic verrucous large cell acanthoma. (2373780)
1990
33
Pilar sheath acanthoma--report of a case with review of the literature. (2697113)
1989
34
Large cell acanthoma. A cytologic variant of Bowen's disease? (3232750)
1988
35
Acantholytic acanthoma. (2461398)
1988
36
Vulvar localisation of epidermolytic acanthoma. A light- and electron-microscopic study. (3743846)
1986
37
Residents' corner: cryosurgery of clear cell acanthoma. (3722579)
1986
38
Disseminated epidermolytic acanthoma. (500873)
1979
39
Pilar sheath acanthoma. (718186)
1978
40
Squamous acanthoma of the oral mucosa. (4530964)
1974
41
Some evidence concerning the sweat duct origin of clear cell acanthoma. (4129605)
1973
42
Isolated epidermolytic acanthoma. A solitary tumor showing granular degeneration. (5413257)
1970
43
The ultrastructure of the pale cell acanthoma. (5774898)
1969
44
Clear cell acanthoma of ear. Report of a case. (5802370)
1969
45
Kerato-acanthoma or squamous carcinoma? (5775799)
1969
46
Adeno-acanthoma of the uterus. (14407697)
1959
47
Kerato-acanthoma; a lesion simulating carcinoma of skin. (13374633)
1956
48
Kerato-acanthoma. (13189828)
1954
49
Uterine adeno-acanthoma with metastasis; report of a case. (13214679)
1954
50
Molluscum sebaceum kerato-acanthoma, benign epithelioma. (12997614)
1952

Variations for Acanthoma

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Expression for genes affiliated with Acanthoma

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Search GEO for disease gene expression data for Acanthoma.

Pathways for genes affiliated with Acanthoma

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GO Terms for genes affiliated with Acanthoma

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Cellular components related to Acanthoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.3KRT10, KRT9

Sources for Acanthoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet