MCID: ACH005
MIFTS: 52

Achalasia malady

Categories: Rare diseases, Gastrointestinal diseases, Cardiovascular diseases

Aliases & Classifications for Achalasia

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Aliases & Descriptions for Achalasia:

Name: Achalasia 11 27 50 13 68
Hypertensive Lower Esophageal Sphincter 11 68
Esophageal Achalasia 11 68
Cardiospasm 11 48
 
Lack of Reflex Relaxation of Lower Oesophageal Sphincter 11
Achalasia of Esophagus 11
Achalasia of Cardia 11

Classifications:



External Ids:

Disease Ontology11 DOID:9164
ICD1030 K22.0
ICD9CM32 530.0
MeSH39 D004931
NCIt45 C84699

Summaries for Achalasia

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Disease Ontology:11 An esophageal disease that is characterized by an inability of the esophagus to move food toward the stomach resulting from the lower esophogeal sphincter not fully relaxing during swallowing.

MalaCards based summary: Achalasia, also known as hypertensive lower esophageal sphincter, is related to achalasia-addisonianism-alacrimia syndrome and idiopathic achalasia. An important gene associated with Achalasia is AAAS (Aladin WD Repeat Nucleoporin), and among its related pathways are Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2 and NO-dependent CFTR activation (normal and CF). Affiliated tissues include smooth muscle, lung and heart, and related mouse phenotypes are Decreased viability after Chlamydia trachomatis serovar L2 infection and TNF-alpha/CHX stimulation and reproductive system.

Wikipedia:71 Achalasia (/eɪkəˈleɪʒə/; a- + -chalasia \"no relaxation\") is a failure of smooth... more...

Related Diseases for Achalasia

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Diseases related to Achalasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 117)
idRelated DiseaseScoreTop Affiliating Genes
1achalasia-addisonianism-alacrimia syndrome12.3
2idiopathic achalasia12.3
3achalasia-microcephaly syndrome12.2
4achalasia, familial esophageal12.2
5moyamoya 6 with achalasia12.2
6alacrima, achalasia, and mental retardation syndrome12.1
7deafness, congenital, with vitiligo and achalasia12.1
8megaesophagus11.3
9mental retardation, x-linked, syndromic 1711.0
10hirschsprung disease 110.7
11ataxia, posterior column, with retinitis pigmentosa10.7
12moyamoya disease10.7
13autoimmune gastrointestinal dysmotility10.7
14gmppa-cdg10.7
15esophagitis10.6
16diabetes insipidus, nephrogenic10.1AAAS, GMPPA, MC2R
17chagas disease10.1
18cough variant asthma10.1KIT, VIP
19idiopathic hypertrophic pachymeningitis10.0AAAS, NOS2, VIPR1
20ovary serous adenocarcinoma10.0KIT, NOS2
21gastroesophageal reflux10.0
22pneumonia10.0
23viral hepatitis9.9NOS1, NOS2, VIP
24choriocarcinoma of ovary9.9KIT, TP53
25sweat gland cancer9.9KIT, RET, VIP
26tmem70 defect9.9RET, TP53
27squamous cell carcinoma9.9
28neuronitis9.9
29fragile x-associated tremor/ataxia syndrome9.9KIT, TP53
30endodermal sinus tumor9.9KIT, TP53
31esophageal cancer9.9
32ovarian embryonal carcinoma9.8KIT, TP53
33aspiration pneumonia9.8
34mediastinitis9.8
35neuropathy9.8
36mycobacterium fortuitum9.8
37dysphagia9.8
38tooth agenesis, selective, 59.8KIT, NOS1, RET, VIP
39mitochondrial dna depletion syndrome 59.8KIT, TP53, VIP
40benign shuddering attacks9.8RET, TP53, VIP
41postpartum depression9.7KIT, TP53
42anorexia nervosa9.7
43lung abscess9.7
44microcephaly9.7
45hiatus hernia9.7
46down syndrome9.7
47adenocarcinoma9.7
48asthma9.7
49obesity9.7
50williams-beuren syndrome9.7

Graphical network of the top 20 diseases related to Achalasia:



Diseases related to achalasia

Symptoms & Phenotypes for Achalasia

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GenomeRNAi Phenotypes related to Achalasia according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00206-A10.4NOS1, NOS2

MGI Mouse Phenotypes related to Achalasia according to GeneCards Suite gene sharing:

41 (show all 15)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053897.9AAAS, KIT, NOS1, NOS2, RET, TP53
2MP:00053697.9GUCY1A3, KIT, NOS1, NOS2, RET, TP53
3MP:00053677.5KIT, NOS1, NOS2, PTPN22, RET, TP53
4MP:00036317.1AAAS, GUCY1A3, KIT, MC2R, NOS1, NOS2
5MP:00053867.0AAAS, KIT, MC2R, NOS1, NOS2, RET
6MP:00053846.8AAAS, KIT, NOS1, NOS2, PTPN22, RET
7MP:00053876.8KIT, MC2R, NOS1, NOS2, PTPN22, RET
8MP:00053886.7GUCY1A3, KIT, NOS1, NOS2, PTPN22, RET
9MP:00053816.6AAAS, KIT, NOS1, NOS2, PTPN22, RET
10MP:00053786.4AAAS, KIT, MC2R, NOS1, NOS2, PTPN22
11MP:00053976.2GUCY1A3, KIT, MC2R, NOS1, NOS2, PTPN22
12MP:00107686.1GUCY1A3, KIT, MC2R, NOS1, NOS2, PTPN22
13MP:00053855.9GUCY1A3, KIT, MC2R, NOS1, NOS2, PTPN22
14MP:00053765.8AAAS, GUCY1A3, KIT, MC2R, NOS1, NOS2
15MP:00053795.8AAAS, KIT, MC2R, NOS1, NOS2, PTPN22

Drugs & Therapeutics for Achalasia

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Drugs for Achalasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 72)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Prednisoneapproved, vet_approvedPhase 4139853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
2
Methylene blueinvestigationalPhase 48961-73-4
Synonyms:
Basic Blue 9
C.I. basic blue 9
Lowacryl blue 9
Methylene blue
Methylene blue anhydrous
Methylthioninium chloride
 
Urolene Blue
aniline violet
methylenium ceruleum
methylthionine chloride
methylthioninium chloride
methylthioninium chloride Proveblue
tetrametylthionine chloride
3Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 413168
4Hormone AntagonistsPhase 413180
5HormonesPhase 414415
6Anti-Inflammatory AgentsPhase 410729
7Antineoplastic Agents, HormonalPhase 45592
8glucocorticoidsPhase 45103
9AnestheticsPhase 3, Phase 29596
10Tin FluoridesPhase 3264
11
MentholapprovedPhase 1, Phase 226062216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
12
Nitric OxideapprovedPhase 1, Phase 261710102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
13
AcetylcholineapprovedPhase 280551-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
14
NaloxegolapprovedPhase 232854601-70-0
Synonyms:
 
(5α,6α)-17-Allyl-6-[(20-hydroxy-3,6,9,12,15,18-hexaoxaicos-1-yl)oxy]-4,5-epoxymorphinan-3,14-diol
15Cholinergic AgentsPhase 23992
16incobotulinumtoxinAPhase 2662
17Neurotransmitter AgentsPhase 218340
18Botulinum Toxins, Type APhase 2657
19Pharmaceutical SolutionsPhase 28192
20onabotulinumtoxinAPhase 2652
21Botulinum ToxinsPhase 2697
22abobotulinumtoxinAPhase 2652
23Peripheral Nervous System AgentsPhase 223689
24Narcotic AntagonistsPhase 2935
25NarcoticsPhase 23646
26
Proton pump inhibitorsPhase 21123
Synonyms:
 
PPIs
27ColaNutraceuticalPhase 21946
28
Amyl Nitriteapproved18017-89-8, 110-46-38053, 10026
Synonyms:
1-nitropentane
3-Methylbutanol nitrite
3-Methylbutyl nitrite
Amilnitrite
Amyl nitrit
Amyl nitrite (JP15/USP)
Amyl nitrite (van)
Amyl nitrite I
Amyl nitrite [usan]
Amyl nitrite(mixed isomers)
Amyl nitrosum
Aspiral (TN)
IPN
Isoamyl nitrite
 
Isopentyl ester Nitrous acid
Isopentyl nitrite
N-Amyl nitrite
N-Pentyl nitrite
Nitramyl
Nitramyl (van)
Nitrite Isopentyl alcohol
Nitrous acid 3-methylbutyl ester
Pentanoli nitris
Pentyl nitrite
Vaporole
Vaporole (TN)
Vaporole amyl nitrite
n-Amyl nitrite
n-pentyl nitrite
pentyl nitrite
29
Ondansetronapproved32699614-02-54595
Synonyms:
(RS)-1,2,3,9-Tetrahydro-9-methyl-3-(2-methylimidazol-1-ylmethyl)carbazol-4-one
1,2,3,9-Tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one
103639-04-9 (mono-hydrochloride dihydrate)
108303-49-7
116002-70-1
9-Methyl-3-(2-methyl-imidazol-1-ylmethyl)-1,2,3,9-tetrahydro-carbazol-4-one
9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one
9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one
99614-01-4 (mono-hydrochloride)
99614-02-5
AB00373674
AC1L1IIM
AKOS000599484
Apo-ondansetron
BAS 00717177
BPBio1_001118
BRD-A19736161-001-01-8
BRD-A19736161-003-03-0
BRN 3622981
BSPBio_001016
C07325
C18H19N3O
CBDivE_008994
CHEMBL46
CID4595
CPD001307702
D00456
DB00904
DESMETHYLONDANSETRON
GR 38032
GR 38032X
GR-38032F
GR38032F
HMS2090H16
I06-0687
I06-1329
 
L000456
LS-172305
LS-51878
MolPort-001-944-253
NCI60_022780
Novo-ondansetron
Ondansetron
Ondansetron (JAN/USP/INN)
Ondansetron [USAN:INN:BAN]
Ondansetron, (+,-)-Isomer
Oprea1_435466
Oprea1_852372
PHL-ondansetron
PMS-ondansetron
Prestwick0_001058
Prestwick1_001058
Prestwick2_001058
Prestwick3_001058
Ratio-ondansetron
SAM002589958
SN-307
SPBio_002938
STK370548
STOCK4S-10990
Sandoz ondansetron
TL8006071
TimTec1_001750
UNII-4AF302ESOS
ZOFRAN IN PLASTIC CONTAINER
Zofran
Zofran ODT
Zofran ODT (TN)
Zofran odt
Zophren
Zudan
ondansetron
ondansetron (Zofran)
30
Diphenhydramineapproved23458-73-1, 147-24-03100
Synonyms:
147-24-0
147-24-0 (HYDROCHLORIDE)
2-(Benzhydryloxy)-N,N-dimethylethylamine
2-(Benzhydryloxy)-N,N-dimethylethylamine, hydrochloride
2-(Diphenylmethoxy)-N,N-dimethylethylamine
2-(diphenylmethoxy)-N,N-dimethylethanamine
2-Diphenylmethoxy-N,N-dimethylethylamine
2-[(diphenylmethyl)oxy]-N,N-dimethylethanamine
2-benzhydryloxy-N,N-dimethylethanamine
2-benzhydryloxyethyl-N,N-dimethylammonium
2-diphenylmethoxy-N,N-demthylethanamine
2PM
58-73-1
88637-37-0 (citrate (1:1))
AB00053460
AC-13704
AC1L1F65
AKOS003658554
Aleryl
Alledryl
Aller-Med
Allerdryl
Allergan
Allergan B
Allergeval
Allergical
Allergina
Allergival
Allermax Caplets
Amidryl
Antistominum
Antitussive
Antomin
Automin
BENADRYL HCl
BIDD:GT0152
BPBio1_000275
BRD-K47278471-003-05-7
BRN 1914136
BSPBio_000249
BSPBio_002219
Bagodryl
Banophen
Banophen Caplets
Baramine
Beldin
Belix
Ben-allergin
Bena
Benachlor
Benadrin
Benadryl
Benadryl (hydrochloride)
Benadryl Allergy
Benapon
Bendylate
Benhydramin
Benodin
Benodine
Benylan
Benylin
Benzantin
Benzantine
Benzhydramine
Benzhydraminum
Benzhydril
Benzhydroamina
Benzhydryl
Betramin
CAS-147-24-0
CCRIS 1959
CHEBI:127629
CHEBI:4636
CHEMBL657
CID3100
CPD-10890
Compoz
D00300
DB01075
DB06975
DIPHENHYDRAMINE, ANTISTOMINUM, BENZHYDRAMINE
Dabylen
Debendrin
Dermistina
Dermodrin
Desentol
Diabenyl
Diabylen
Dibendrin
Dibenil
Dibondrin
Difedryl
Difenhidramina
Difenhidramina [INN-Spanish]
Difenhydramin
Difenhydramine
Difenidramina
Difenidramina [Italian]
Dihidral
Dimedrol
Dimedrol base
Dimedrolum
Dimedryl
Dimehydrinate
Dimethylamine benzhydryl ester
Diphamine
Diphantine
Diphen
 
Diphen Cough
Diphenhist
Diphenhist Captabs
Diphenhydramine
Diphenhydramine (JP15/INN)
Diphenhydramine Base
Diphenhydramine HCl
Diphenhydramine [INN:BAN:JAN]
Diphenhydraminum
Diphenhydraminum [INN-Latin]
Diphenylhydramin
Diphenylhydramine
DivK1c_000368
Dobacen
Dormarex 2
Dryistan
Drylistan
Dylamon
EINECS 200-396-7
Etanautine
FAR 90X2
Genahist
HMS2089E06
HSDB 3066
Histaxin
Hyadrine
Hydramine
Hyrexin
I14-6749
IDI1_000368
Ibiodral
KBio1_000368
KBio2_001460
KBio2_004028
KBio2_006596
KBio3_001439
KBioGR_001099
KBioSS_001460
L000227
LS-68208
Lopac-D-3630
Lopac0_000377
MLS002222276
Medidryl
Mephadryl
MolPort-001-783-508
N,N-Dimethyl-2-(diphenylmethoxy)-ethylamine hydrochloride
N-(2-(Diphenylmethoxy)ethyl)-N,N-dimethylamine
N-(Benzhydryloksy-etylo)dwumetyloamina
N-(Benzhydryloksy-etylo)dwumetyloamina [Polish]
N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE
NCGC00015335-01
NCGC00015335-02
NCGC00015335-03
NCGC00015335-10
NCGC00024414-03
NCGC00024414-04
NCI60_002916
NCI60_022782
NINDS_000368
NSC665800
Nausen
Nervine Nighttime Sleep-Aid
Novamina
Nytol Quickcaps
Nytol Quickgels
O-Benzhydryldimethylaminoethanol
O-benzhydryldimethylaminoethanol
Oprea1_254625
PM 255
Prestwick0_000065
Prestwick1_000065
Prestwick2_000065
Prestwick3_000065
Probedryl
Restamin
Restamin (TN)
Rigidil
S51
SMR001307259
SPBio_000961
SPBio_002170
STK103720
STOCK2S-94461
Siladryl
Silphen
Sleep-Eze D
Sleep-Eze D Extra Strength
Spectrum2_000961
Spectrum3_000400
Spectrum4_000520
Spectrum5_000915
Spectrum_000980
Syntedril
Syntodril
TL8003758
Twilite Caplets
UNII-8GTS82S83M
Unisom Sleepgels Maximum Strength
alpha-(2-Dimethylaminoethoxy)diphenylmethane
beta-Dimethylamino-aethyl-benzhydryl-aether
beta-Dimethylamino-aethyl-benzhydryl-aether [German]
beta-Dimethylaminoethanol diphenylmethyl ether
beta-Dimethylaminoethyl benzhydryl ether
beta-Dimethylaminoethylbenzhydrylether
beta-dimethylaminoethyl benzhydryl ether
diphenhydramine
nchembio747-comp18
β-dimethylaminoethyl benzhydryl ether
31
Histamineapproved, investigational105075614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-(4-imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
4-imidazoleethylamine
5-Imidazoleethylamine
5-imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminoethylglyoxaline
beta-aminoethylimidazole
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
32
Promethazineapproved23460-87-74927
Synonyms:
(2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
(2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
(Dimethylamino-2-propyl-10-phenothiazine hydrochloride
10-(2-(Dimethylamino)-2-methylethyl)phenothiazine
10-(2-(Dimethylamino)propyl)phenothiazine
10-(2-Dimethylaminopropyl)phenothiazine
10-[2-(Dimethylamino)propyl]phenothiazine
10-[2-(dimethylamino)Propyl]phenothiazine
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl- (9CI)
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, radical ion(1+)
3277 RP
3389 R.p.
38878-40-9
4-27-00-01253 (Beilstein Handbook Reference)
4182 R.p.
60-87-7
73745-50-3
A-91033
AB00053535
AC-15939
AC1L1J92
Antiallersin
Aprobit
Avomine
BPBio1_000744
BRN 0088554
BSPBio_000676
BSPBio_002777
C07404
CCRIS 7056
CHEBI:8461
CHEMBL643
CID4927
Camergan
D00494
DB01069
Dimapp
Dimethylamino-isopropyl-phenthiazin
Dimethylamino-isopropyl-phenthiazin [German]
Diphergan
Diprazin
Diprazine
Diprozin
DivK1c_000005
EINECS 200-489-2
Fargan
Fenazil
Fenetazina
Fenetazine
Genphen
HMS2089E08
HSDB 3173
Hiberna
Histargan
IDI1_000005
Iergigan
InChI=1/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
Isophenergan
Isopromethazine
KBio1_000005
KBio2_001348
KBio2_003916
KBio2_006484
KBio3_001997
KBioGR_001697
KBioSS_001348
L000495
LS-264
Lercigan
Lergigan
Lilly 01516
Lilly 1516
Lopac0_000899
Metaryl
MolPort-001-783-684
N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine
N,N,α-trimethyl-10H-phenothiazine-10-ethanamine
N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine
 
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine hydrochloride
N-(2'-Dimethylamino-2'-methyl)ethylphenothiazine
N-(2'-dimethylamino-2'-Methyl)ethylphenothiazine
N-Dimethylamino-2-methylethyl thiodiphenylamine
NCGC00015817-10
NCGC00089735-02
NCGC00089735-03
NCI-C60673
NCI60_001878
NINDS_000005
NSC 30321
NSC30321
Oprea1_758749
PROMETHAZINE (SEE ALSO PROMETHAZINE HYDROCHLORIDE 58-33-3)
Pelpica
Phargan
Phenargan
Phenerzine
Phenoject-50
Phensedyl
Pilothia
Pilpophen
Pipolphene
Prestwick0_000888
Prestwick1_000888
Prestwick2_000888
Prestwick3_000888
Pro-50
Proazaimine
Proazamine
Procit
Promacot
Promazinamide
Promergan
Promesan
Prometasin
Prometazin
Prometazina
Prometazina [INN-Spanish]
Prometazine
Prometh
Promethacon
Promethaine
Promethazin
Promethazine
Promethazine (JAN/INN)
Promethazine [INN:BAN]
PromethazineHcl
Promethazinum
Promethazinum [INN-Latin]
Promethegan
Promethiazine
Promezathine
Prorex
Protazine
Prothazin
Prothazine
Provigan
Pyrethia
Pyrethiazine
RP 3277
Remsed
Romergan
Rumergan
SKF 1498
SPBio_000799
SPBio_002895
Spectrum2_000840
Spectrum3_001019
Spectrum4_001149
Spectrum5_000977
Spectrum_000868
Tanidil
Thiergan
UNII-FF28EJQ494
Valergine
Vallergine
WLN: T C666 BN ISJ B1Y1&N1&1
WY 509
Zipan-25
promethazine
33
Benzocaineapproved20161994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
34
Domperidoneapproved, investigational, vet_approved4957808-66-93151
Synonyms:
1-(3-(4-(5-chloro-2-oxo-2,3-Dihydrobenzo[D]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[D]imidazol-2(3H)-one
4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine
5-24-02-00402 (Beilstein Handbook Reference)
5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone
5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]- 1,3-dihydro-2H-benzimidazol-2-one
5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone
5-chloro-1-(1-(3-(2-oxo-1-Benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone
5-chloro-1-(1-(3-(2-oxo-2,3-Dihydrobenzo[D]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[D]imidazol-2(3H)-one
5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one
5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one
57808-66-9
6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
83898-65-1 (maleate (1:1))
99497-03-7 (maleate)
AB00052423
AC-2037
AC1L1FAB
BPBio1_000620
BPBio1_001185
BRD-K38305202-001-02-6
BRN 0903774
BSPBio_002350
Biomol-NT_000022
C22H24ClN5O2
CHEBI:31515
CHEBI:464745
CHEMBL219916
CID3151
D-122
D01745
D122_SIGMA
DB01184
DivK1c_006921
Domperidon
Domperidona
Domperidona [INN-Spanish]
Domperidone (JAN/USAN/INN)
Domperidone [USAN:BAN:INN:JAN]
Domperidonum
Domperidonum [INN-Latin]
EINECS 260-968-7
EU-0100427
HMS1922N04
HMS2089C14
HMS2093N22
HS-0067
I01-0054
I14-14161
KBio1_001865
KBio2_000871
 
KBio2_003439
KBio2_006007
KBioGR_000354
KBioSS_000871
KW 5338
KW-5338
L000230
LS-33301
Lopac-D-122
Lopac0_000427
MLS000859942
MLS001306482
MLS002222324
Motilium
Motilium (TN)
NCGC00014670
NCGC00014670-05
NCGC00014670-13
NCGC00015306-01
NCGC00021472-02
NCGC00021472-03
NCGC00021472-04
NCGC00021472-05
NCGC00021472-06
NCGC00021472-07
NCGC00021472-08
NCGC00097773-01
NCI299589
NCI60_002512
NCIStruc1_001686
NCIStruc2_001819
NSC-299589
NSC299589
Nauzelin
Prestwick0_000461
Prestwick1_000461
Prestwick2_000461
Prestwick3_000461
Prestwick_794
R 33,812
R-33,812
R-33812
S2461_Selleck
SMR000326802
SPBio_002501
SPECTRUM2300212
STK622843
SpecPlus_000825
Spectrum4_000087
Spectrum_000391
UNII-5587267Z69
domperidone
35
Esomeprazoleapproved, investigational333161796-78-7, 119141-88-74594, 9579578
Synonyms:
( -)-Omeprazole
(-)-Omeprazole
(-)-omeprazole
(S)-(-)-Omeprazole
(S)-(−)-omeprazole
(S)-Omeprazole
(S)-omeprazole
(s)-omeprazole
(−)-omeprazole
119141-88-7
119141-89-8
131959-78-9
172964-80-6
193469-77-1
2-(((3,5-Dimethyl-4-methoxy-2-pyridyl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole
2-({[3,5-dimethyl-4-(methyloxy)pyridin-2-yl]methyl}sulfinyl)-5-(methyloxy)-1H-benzimidazole
326602-80-6
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole
5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1-methyl-1H-benzimidazole
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
73590-58-6
AC-401
AC1L1IIJ
AGI-010
AKOS005066653
AULCER
Antra
Antra MUPS
Audazol
Axagon
BIDD:GT0020
BIDD:GT0189
BPBio1_000425
BRD-A55962179-001-04-9
BSPBio_000385
Belmazol
Bio-0888
C07324
CAS-73590-58-6
CCRIS 7099
CHEBI:50275
CHEBI:519601
CHEBI:7772
CHEMBL1503
CID4594
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CID9579578
CPD000058847
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D00455
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HMS1528I05
HMS1569D07
HMS2052G17
HMS2090E16
HMS2090F11
HSDB 3575
I06-0705
IDI1_032523
InChI=1/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20
Indurgan
Inexium paranova
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Inhibitron
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LS-185188
LS-7629
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Losec
Losec, Omesec, Prilosec, Zegerid, Omeprazole
Lucen
MLS000069373
MLS001076112
MLS001424148
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Mepral
 
Miol
Miracid
MolPort-003-666-741
MolPort-003-807-515
MolPort-003-849-702
MolPort-005-943-880
Mopral
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NCGC00016925-01
NCGC00016925-02
NCGC00021522-03
NCGC00021522-04
NCGC00021522-05
Nexiam
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O0359
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esomeprazol
esomeprazole
esomeprazolum
omeprazole
Ésoméprazole
36
Dopamineapproved383651-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
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Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
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Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
37tannic acidapproved, Nutraceutical2016
38Anti-Infective Agents22062
39Hypnotics and Sedatives2616
40Anti-Bacterial Agents11226
41Antitubercular Agents1343
42Anesthetics, Local3492
43Analgesics11733
44Hemostatics1443
45Vasodilator Agents3543
46Cephalosporins168
47Antibiotics, Antitubercular7180
48Tranquilizing Agents4265
49Dermatologic Agents5806
50Serotonin Agents3156

Interventional clinical trials:

(show top 50)    (show all 79)
idNameStatusNCT IDPhase
1Personalized Peroral Endoscopic Myotomy for AchalasiaUnknown statusNCT01570621Phase 4
2Assessing the Efficacy of Steroid Treatment of AchalasiaEnrolling by invitationNCT01903486Phase 4
3Comparison of Esophageal and Anorectal Manometry CathetersTerminatedNCT00204763Phase 4
4Peroral Endoscopic Myotomy for Primary Esophageal AchalasiaCompletedNCT01560559Phase 3
5Efficacy of Dark Chocolate in Achalasia PatientsUnknown statusNCT00790465Phase 1, Phase 2
6Endolumenal Partial Myotomy for the Treatment of Esophageal AchalasiaUnknown statusNCT01302288Phase 2
7Prospective Study on the Feasibility and Effectiveness of Per-Oral Endoscopic Myotomy (P.O.E.M.) for Treatment of Primary Esophageal Motility DisordersUnknown statusNCT01524458Phase 1, Phase 2
8Endolumenal Partial Myotomy for Esophageal Motility DisordersUnknown statusNCT01302301Phase 2
9Per-Oral Endoscopic Myotomy (P.O.E.M.) for Treatment of Primary Esophageal Motility DisordersUnknown statusNCT01524471Phase 2
10Prospective Study on the Feasibility and Results of POEM in Idiopathic AchalasiaCompletedNCT02259283Phase 2
11Peroral Endoscopic Myotomy (POEM) for the Treatment of AchalasiaCompletedNCT02073578Phase 1, Phase 2
12Pneumatic Dilatation or Surgical Myotomy for AchalasiaCompletedNCT02086669Phase 2
13Endoscopic Myotomy for the Treatment of Achalasia (Motility Disorder) of the Esophagus - POEM ProcedureCompletedNCT01873300Phase 1, Phase 2
14Study of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Type II AchalasiaRecruitingNCT02931565Phase 2
15Movantik for Opioid-Related Esophageal DisordersRecruitingNCT02998606Phase 2
16Peroral Endoscopic Myotomy Versus Botulinum Toxin Injection in Spastic Esophageal DisordersNot yet recruitingNCT02663206Phase 2
17Evaluation of the Safety and Effectiveness of Tailored Transoral Incisionless Fundoplication (TIF) Using EsophyX for the Treatment of GERDWithdrawnNCT01025739Phase 2
18Endoscopic Myotomy of the Lower Esophageal Sphincter for AchalasiaUnknown statusNCT01399476Phase 1
19Per-Oral Endoscopic MyotomyRecruitingNCT01402518Phase 1
20Clinical Impact of Peroral Endoscopic Myotomy for Esophageal AchalasiaUnknown statusNCT01649843
21Hot Water Drinking Therapy in AchalasiaUnknown statusNCT01863966
22Achalasia: Mechanisms Underlying Treatment FailureUnknown statusNCT02055469
23POEM vs. Pneumatic Dilation for Esophageal AchalasiaUnknown statusNCT01768091
24POEM Versus Pneumatic Dilatation in Achalasia CardiaUnknown statusNCT02025790
25Prospective Study to Assess the Diagnostic Utility of Amyl Nitrite in Patients With Suspected Achalasia Undergoing High Resolution Esophageal Manometry (HREM)Unknown statusNCT02428959
26A Randomized Comparison of Laparoscopic Myotomy and Pneumatic Dilatation for AchalasiaUnknown statusNCT00188344
27Comparison Study of Conventional POEM and Hybrid POEM for Esophageal AchalasiaUnknown statusNCT01742494
28Bacteremia and Procalcitonin Levels in Peroral Endoscopic Myotomy for AchalasiaUnknown statusNCT01750385
29Peroral Endoscopic Remyotomy for Failed Heller MyotomyUnknown statusNCT01637311
30Reversibility of Dysmotility After Gastric BandingUnknown statusNCT00680030
31Pyloric Sphincter Pressure and Geometry Assessment Using EndoFlipUnknown statusNCT02446119
32Functional Endoscopy in Neurogenic DysphagiaUnknown statusNCT01995929
33The Role That Peroral Endoscopic Myotomy (POEM) Could Play in the Treatment of AchalasiaCompletedNCT01584635
34Genetic Evaluation of AAAS Gene in Early-Onset Achalasia and Alacrima PatientsCompletedNCT00856921
35Endoscopic Peroral Myotomy for Treatment of AchalasiaCompletedNCT01405469
36A Clinical Study of Per Oral Endoscopic Myotomy (POEM) in Patients Suffering From AchalasiaCompletedNCT01692106
37Evaluation of a Novel Endoscopic Treatment for AchalasiaCompletedNCT01770249
38A Prospective Study Comparing Two Reconstructive Operation Techniques After Myotomy of AchalasiaCompletedNCT01933373
39Peroral Endoscopic Myotomy (POEM) for Esophageal MotilityCompletedNCT02314741
40Do Patients Who Have Had Surgery for Achalasia Suffer From RefluxCompletedNCT00519441
41Efficacy & Safety of Submucosal Endoscopic Myotomy With Mucosal Flap (SEMF) in the Treatment of Patients With AchalasiaCompletedNCT01438398
42Randomized Study of Botulinum Toxin Type A for AchalasiaCompletedNCT00004416
43Laparoscopic Dor Versus Toupet Fundoplication for the Treatment of Idiopathic Esophageal AchalasiaCompletedNCT00490750
44Per-Oral Endoscopic Esophagomyotomy (POEM)CompletedNCT01635374
45Per-Oral Endoscopic Myotomy (P.O.E.M.) for Treatment of Esophageal Motility DisordersCompletedNCT01525732
46SX ELLA Esophageal Degradable BD Stent SystemCompletedNCT01337206
47Reletex Versus Standard of Care Therapy for Post-Operative Nausea Control in Patients Undergoing Foregut SurgeryCompletedNCT01510379
48Normal Values in Ano-rectal 3D High Resolution ManometryCompletedNCT01710579
49Pancreaticobiliary Reflux in Patients Without CholelithiasisCompletedNCT00890201
50Peroral Endoscopic Myotomy (POEM) for the Treatment of AchalasiaRecruitingNCT01832779

Search NIH Clinical Center for Achalasia

Genetic Tests for Achalasia

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Genetic tests related to Achalasia:

id Genetic test Affiliating Genes
1 Achalasia27

Anatomical Context for Achalasia

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MalaCards organs/tissues related to Achalasia:

36
Smooth muscle, Lung, Heart, Testes, Thyroid, Brain

Publications for Achalasia

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Articles related to Achalasia:

(show top 50)    (show all 765)
idTitleAuthorsYear
1
Intramural esophageal bronchogenic cyst mimicking achalasia in a toddler. (27822780)
2017
2
Impaired bolus clearance in combined high-resolution esophageal manometry and impedance measurement helps to differentiate between esophagogastric junction outflow obstruction and achalasia. (28068730)
2017
3
Results of Laparoscopic Heller's Myotomy for Achalasia in Children: A Systematic Review of the Literature. (27901639)
2017
4
Peroral endoscopic myotomy for an achalasia patient with multiple esophageal diverticula. (27967203)
2017
5
The course of achalasia one to four decades after initial treatment. (27925255)
2017
6
A Rare Case of Esophageal Verrucous Squamous Cell Carcinoma in a Patient with Achalasia. (28063972)
2017
7
Diagnosis and Treatment Strategy of Achalasia Subtypes and Esophagogastric Junction Outflow Obstruction Based on High-Resolution Manometry. (28052278)
2017
8
Achalasia-microcephaly syndrome: a further case report. (28471776)
2017
9
EUS-guided per-oral endoscopic myotomy to treat an achalasia with relapse after Heller's myotomy. (27178311)
2016
10
Progression of Jackhammer Esophagus to Achalasia. (27032546)
2016
11
Idiopathic hypereosinophilic syndrome presenting with hepatitis and achalasia. (27294613)
2016
12
Peroral endoscopic myotomy after gastric bypass: An effective solution for de novo achalasia. (27916564)
2016
13
Long-term efficacy of modified retrievable stents for treatment of achalasia cardia. (27059970)
2016
14
Use of a long, stiff, overtube placed by a colonoscope to facilitate the POEM procedure for a 36-year history of achalasia with 13-cm esophageal dilation. (27213966)
2016
15
Per-oral endoscopic pyloromyotomy and per-oral endoscopic myotomy for coexisting refractory gastroparesis and recurrent achalasia cardia in a single patient. (27090287)
2016
16
Update on Therapeutic Interventions for the Management of Achalasia. (27060999)
2016
17
Heller Myotomy Is Superior to Balloon Dilatation or Botulinum Injection in Children with Achalasia: A Two-Center Review. (27135255)
2016
18
Tracheomalacia Due to Esophageal Achalasia. (27364977)
2016
19
Mutations in CRLF1 cause familial achalasia. (27976805)
2016
20
Gene expression of muscular and neuronal pathways is cooperatively dysregulated in patients with idiopathic achalasia. (27511445)
2016
21
Megaesophagus in Achalasia. (27140718)
2016
22
Laparoscopic myotomy after transjugular intrahepatic portosystemic shunt placement and embolization of gastroesophageal varices in patients with achalasia and cirrhosis. (27939056)
2016
23
Esophagus-Related Symptoms in First-Degree Relatives of Patients with Achalasia: Is Screening Necessary? (27921050)
2016
24
Laparoscopic Heller Myotomy and Dor Fundoplication for Esophageal Achalasia: Technique and Perioperative Management. (27606723)
2016
25
Effects of laparoscopic myotomy on the esophageal motility pattern of esophageal achalasia as measured by high-resolution manometry. (28039638)
2016
26
Etiology and Pathogenesis of Idiopathic Achalasia. (28009686)
2016
27
Progression of Jackhammer Esophagus to Achalasia: Author's Reply. (27032547)
2016
28
Diagnosis and management of esophageal achalasia. (27625387)
2016
29
Letter to the Editor: More on Achalasia with Megaesophagus. (27574362)
2016
30
Gender differences in both the pathology and surgical outcome of patients with esophageal achalasia. (27129544)
2016
31
Pneumatic Dilation for Achalasia: Obliterate the Waist! (27580786)
2016
32
Massive food impaction in achalasia. (27981296)
2016
33
Socio-economic status and lifestyle factors are associated with achalasia risk: A population-based case-control study. (27099443)
2016
34
Oesophageal disease: gastroesophageal reflux disease, Barrett's oesophagus, achalasia and eosinophilic oesophagitis. (27888864)
2016
35
Two-Person Technique of Peroral Endoscopic Myotomy for Achalasia with an Advanced Endoscopist and a Thoracic Surgeon: Initial Experience. (27630977)
2016
36
Per Oral Endoscopic Myotomy for Achalasia: A Detailed Description of the Technique and Review of the Literature. (27112254)
2016
37
Prosthetic rehabilitation in patient with achalasia cardia - A rare case report. (27583229)
2016
38
Anaesthetic Management of a Case of Down's Syndrome with Achalasia Cardia. (27891427)
2016
39
Peroral endoscopic myotomy: ready for prime time in all achalasia patients? (27894134)
2016
40
Pyopericardium secondary to achalasia-associated squamous cell carcinoma of the oesophagus. (27551899)
2016
41
Achalasia case detected during endoscopy application accompanied by anaesthesia. (28053688)
2016
42
A Matched Comparison of Per Oral Endoscopic Myotomy to Laparoscopic Heller Myotomy in the Treatment of Achalasia. (27514392)
2016
43
Do Jackhammer contractions lead to achalasia? A longitudinal study. (27660053)
2016
44
Clinical response to peroral endoscopic myotomy in patients with idiopathic achalasia at a minimum follow-up of 2a88years. (25934759)
2016
45
Safety and efficacy of POEM for treatment of achalasia: a systematic review of the literature. (27633440)
2016
46
Per-oral Endoscopic Myotomy in Children with Achalasia Cardia. (27048658)
2016
47
Long-term outcome of peroral endoscopic myotomy for achalasia treatment in a 9-year-old female patient. (27188526)
2016
48
Comprehensive epidemiological and genotype-phenotype analyses in a large European sample with idiopathic achalasia. (26882171)
2016
49
Lung Abscess: Atypical Presentation of Achalasia. (27079347)
2016
50
Peroral endoscopic myotomy versus pneumatic dilation for achalasia in patients aged a8Y 65 years. (27649684)
2016

Variations for Achalasia

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Expression for genes affiliated with Achalasia

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Search GEO for disease gene expression data for Achalasia.

Pathways for genes affiliated with Achalasia

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GO Terms for genes affiliated with Achalasia

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Biological processes related to Achalasia according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1arginine catabolic processGO:000652710.3NOS1, NOS2
2negative regulation of blood pressureGO:004577610.3NOS1, NOS2
3nitric oxide biosynthetic processGO:000680910.3NOS1, NOS2
4peptidyl-cysteine S-nitrosylationGO:001811910.3NOS1, NOS2
5positive regulation of guanylate cyclase activityGO:003128410.1NOS1, NOS2
6nitric oxide mediated signal transductionGO:000726310.0GUCY1A3, NOS1, NOS2
7T cell differentiationGO:00302179.2KIT, PTPN22
8positive regulation of gene expressionGO:00106288.5KIT, PTPN22, RET, TP53

Molecular functions related to Achalasia according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1arginine bindingGO:003461810.3NOS1, NOS2
2FMN bindingGO:001018110.2NOS1, NOS2
3NADP bindingGO:005066110.0NOS1, NOS2
4NADPH-hemoprotein reductase activityGO:00039589.8NOS1, NOS2
5heme bindingGO:00200379.8GUCY1A3, NOS1, NOS2
6nitric-oxide synthase activityGO:00045179.7NOS1, NOS2
7tetrahydrobiopterin bindingGO:00346179.7NOS1, NOS2

Sources for Achalasia

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet