Aliases & Classifications for Acne

MalaCards integrated aliases for Acne:

Name: Acne 38 12 29 41 14 69
Acne Vulgaris 12 52 69
Acne Varioliformis 12 69
Frontalis Acne 12

Classifications:



Summaries for Acne

MedlinePlus : 41 acne is a common skin disease that causes pimples. pimples form when hair follicles under your skin clog up. most pimples form on the face, neck, back, chest, and shoulders. anyone can get acne, but it is common in teenagers and young adults. it is not serious, but it can cause scars. no one knows exactly what causes acne. hormone changes, such as those during the teenage years and pregnancy, probably play a role. there are many myths about what causes acne. chocolate and greasy foods are often blamed, but there is little evidence that foods have much effect on acne in most people. another common myth is that dirty skin causes acne; however, blackheads and pimples are not caused by dirt. stress doesn't cause acne, but stress can make it worse. if you have acne clean your skin gently try not to touch your skin avoid the sun treatments for acne include medicines and creams. nih: national institute of arthritis and musculoskeletal and skin diseases

MalaCards based summary : Acne, also known as acne vulgaris, is related to sinusitis and pyogenic arthritis, pyoderma gangrenosum and acne, and has symptoms including exanthema and pruritus. An important gene associated with Acne is NCSTN (Nicastrin), and among its related pathways/superpathways are Innate Immune System and Development NOTCH1-mediated pathway for NF-KB activity modulation. The drugs Benzoyl peroxide and Clindamycin have been mentioned in the context of this disorder. Affiliated tissues include skin, ovary and testes, and related phenotypes are Increased shRNA abundance and integument

Disease Ontology : 12 A sebaceous gland disease characterized by areas of blackheads, whiteheads, pimples, greasy skin, and possibly scarring.

Wikipedia : 72 Acne, also known as acne vulgaris, is a long-term skin disease that occurs when hair follicles are... more...

Related Diseases for Acne

Diseases related to Acne via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 243)
id Related Disease Score Top Affiliating Genes
1 sinusitis 29.8 CXCL8 IL1A IL1RN
2 pyogenic arthritis, pyoderma gangrenosum and acne 12.2
3 acne inversa, familial, 3 12.1
4 acne inversa, familial, 2 12.1
5 retinal dystrophy, iris coloboma, and comedogenic acne syndrome 12.1
6 acne inversa, familial, 1 12.1
7 pyogenic sterile arthritis, pyoderma gangrenosum, and acne 12.0
8 hidradenitis suppurativa 11.8
9 pyoderma gangrenosum-acne-suppurative hidradenitis syndrome 11.7
10 sapho syndrome 11.7
11 anterior cutaneous nerve entrapment syndrome 11.7
12 rosacea 11.6
13 polycystic ovary syndrome 11.3
14 dowling-degos disease 11.2
15 hyperandrogenism 11.0
16 granulomatous rosacea 11.0
17 nevus comedonicus, somatic 10.8
18 aromatase deficiency 10.8
19 isotretinoin syndrome 10.8
20 mycobacterium malmoense 10.8 CXCL8 TLR2
21 benign dermal neurilemmoma 10.7 NCSTN PSEN1 PSENEN
22 female reproductive system disease 10.7 NCSTN PSEN1 PSENEN
23 leptospirosis 10.7 NCSTN PSEN1 PSENEN
24 familial male-limited precocious puberty 10.6
25 darier disease 10.6
26 skin conditions 10.6
27 hair-an syndrome 10.6
28 frank-ter haar syndrome 10.6
29 adrenal hyperplasia, congenital, due to 21-hydroxylase deficiency 10.6
30 diabetes mellitus, insulin-resistant, with acanthosis nigricans 10.6
31 isotretinoin embryopathy-like syndrome 10.6
32 cushing's syndrome 10.6
33 urbach-wiethe disease 10.6
34 perifolliculitis capitis abscedens et suffodiens, familial 10.6
35 fetal retinoid syndrome 10.6
36 central precocious puberty 10.6
37 mycobacterium xenopi 10.6 CXCL8 TLR2
38 tumefactive multiple sclerosis 10.5 CXCL8 GGT1 TLR2
39 lymph node palisaded myofibroblastoma 10.5 CXCL8 IL1A
40 burns 10.5 CXCL8 IL1RN RBP4
41 askin's tumor 10.5 IL1A IL1RN TLR2
42 asbestosis 10.4 CAT CXCL8 IL1A
43 scleroperikeratitis 10.4 IL1RN NCSTN PSENEN PSTPIP1
44 vulva fibroepithelial polyp 10.4 CXCL8 IL1A TLR2
45 cerebellar disease 10.4 CXCL8 FLG IL1A
46 pleomorphic lipoma 10.4 CXCL8 IL1A IL1RN
47 ragweed sensitivity 10.4 CXCL8 IL1A IL1RN
48 mesenchymal cell neoplasm 10.3 CXCL8 IL1A IL1RN
49 hidradenitis 10.3
50 synovitis 10.3

Graphical network of the top 20 diseases related to Acne:



Diseases related to Acne

Symptoms & Phenotypes for Acne

UMLS symptoms related to Acne:


exanthema, pruritus

GenomeRNAi Phenotypes related to Acne according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance GR00327-A 9.1 CAT CYP1A1 DEFB1 FGFR2 G6PD IL1RN

MGI Mouse Phenotypes related to Acne:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.23 FGFR2 GGT1 IL1A IL1RN NCSTN PSEN1

Drugs & Therapeutics for Acne

Drugs for Acne (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 384)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzoyl peroxide Approved Phase 4,Phase 3,Phase 2,Phase 1 94-36-0 7187
2
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 18323-44-9 29029
3
Lymecycline Approved Phase 4,Phase 3 992-21-2 5280963
4
Minocycline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 10118-90-8 5281021
5
Adapalene Approved Phase 4,Phase 3,Phase 1,Phase 2 106685-40-9 60164
6
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
7
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
8
Prilocaine Approved Phase 4 721-50-6 4906
9 Racepinephrine Approved Phase 4,Phase 2
10
Ciclopirox Approved, Investigational Phase 4 29342-05-0 2749
11
Isotretinoin Approved Phase 4,Phase 3,Phase 2,Phase 1 4759-48-2 5538 5282379
12
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 22916-47-8 4189
13
Salicylic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 69-72-7 338
14
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 564-25-0 54671203
15
Tazarotene Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 118292-40-3 5381
16
Dapsone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 80-08-0 2955
17
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-28-2 5757
18
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2,Phase 1 57-63-6 5991
19
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 1 9004-61-9 53477741 24759
20
Azelaic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 123-99-9 2266
21
Drospirenone Approved Phase 4,Phase 3,Phase 2 67392-87-4 68873
22
Aminolevulinic acid Approved Phase 4,Phase 2,Phase 1 106-60-5 137
23
Desogestrel Approved Phase 4 54024-22-5 40973
24
Moxifloxacin Approved, Investigational Phase 4,Phase 1 354812-41-2, 151096-09-2 152946
25
Norgestimate Approved Phase 4,Phase 1 35189-28-7 6540478
26
Norgestrel Approved Phase 4 6533-00-2 13109
27
Cyproterone Acetate Approved, Investigational Phase 4,Phase 3 427-51-0
28
Benzocaine Approved Phase 4,Phase 2 1994-09-7, 94-09-7 2337
29
Tetracaine Approved, Vet_approved Phase 4 94-24-6 5411
30
Coal tar Approved Phase 4,Phase 1 8007-45-2
31
Metformin Approved Phase 4,Phase 3 657-24-9 14219 4091
32
Desonide Approved, Investigational Phase 4 638-94-8 5311066
33
Hydroxocobalamin Approved Phase 4 13422-51-0 11953898 5460373 44475014
34
Ethanol Approved Phase 4,Phase 2 64-17-5 702
35
Glycerol Approved, Investigational Phase 4 56-81-5 753
36
Kinetin Approved Phase 4 525-79-1 3830
37
Polidocanol Approved Phase 4 9002-92-0
38
Adalimumab Approved Phase 4,Phase 3 331731-18-1 16219006
39
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
40
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
41
Mycophenolic acid Approved Phase 4 24280-93-1 446541
42
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
43
Azathioprine Approved Phase 4 446-86-6 2265
44
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
45
Tretinoin Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 302-79-4 5538
46
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 59-30-3 6037
47
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 59-67-6 938
48
Nicotinamide Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 98-92-0 936
49
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 58-05-9 143 6006
50 Tocopherol Approved, Nutraceutical Phase 4

Interventional clinical trials:

(show top 50) (show all 589)

id Name Status NCT ID Phase Drugs
1 Safety and Tolerability of Acanya Gel in Combination With Atralin Gel for Acne Vulgaris Unknown status NCT01448733 Phase 4 Benzoyl peroxide 2.5%/clindamycin phosphate 1.2% in the morning with with tretinoin 0.05% gel in the evening
2 A Study Comparing Combination Clindamycin Phosphate/Tretinoin Gel Alone Versus With Benzoyl Peroxide Foaming Cloths for Facial Acne Unknown status NCT01422785 Phase 4 clindamycin phosphate 1.2%/tretinoin 0.025% gel alone;clindamycin phosphate 1.2%/tretinoin 0.025% gel plus benzoyl peroxide 6% foaming cloths
3 Efficacy & Safety of Clindamycin and Tretinoin in Acne Unknown status NCT01111994 Phase 4 Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel
4 Clinical Study to Evaluate the Efficacy of Topical Medications Containing Benzoyl Peroxide and Sulfur in the Regression in the Short Time (24 Hours) of Moderate Acne Vulgaris Grade II (Pimples) Unknown status NCT01260571 Phase 4 Benzoyl peroxide and sulfur
5 Safety and Efficacy Comparison of Minocycline Microgranules Versus Lymecycline in the Treatment of Mild to Moderate Acne Unknown status NCT00988026 Phase 4 Minocycline vs Lymecycline
6 Control of Therapy of Acne Papulopustulosa by Visible Light With Waterfiltered Infrared and / or Adapalen (Differin Gel) Unknown status NCT00237978 Phase 4 Adapalen
7 Fractional Laser Assisted Topical Anesthesia Unknown status NCT02548533 Phase 4 AHES;EMLA cream
8 Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea Unknown status NCT01139749 Phase 4 oral isotretinoin;salicylic acid and ciclopirox olamine
9 VSL#3 Treatment in Children With Crohn's Disease Unknown status NCT00367705 Phase 4
10 Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne Completed NCT00837213 Phase 4 Benzoyl peroxide with clindamycin;Benzoyl peroxide with clindamycin and doxycycline
11 Adherence to Study Medication Compared to Generic Topical Clindamycin Plus Generic Topical Tretinoin in Subjects With Mild to Moderate Acne Vulgaris Completed NCT01047189 Phase 4 clindamycin phosphate 1.2% and tretinoin 0.025%;clindamycin 1% gel;tretinoin 0.025% cream
12 Comparison Study of Topical Acne Regimens Completed NCT00913185 Phase 4 Acne Free, Proactiv
13 A Treatment Regimen for Student Athletes With Mild to Moderate Acne Vulgaris Completed NCT02249104 Phase 4 Adapalene/benzoyl peroxide gel, 0.1%/2.5%
14 Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Facial Acne Completed NCT00841776 Phase 4 Duac;Ziana gel
15 Anti Propionibacterium(P.) Acnes Activity of Epiduo® Gel Compared to Benzoyl Peroxide (BPO) 2.5% Gel Completed NCT01188538 Phase 4 Epiduo gel;BPO
16 A Study of Different Use Regimens Using Two Acne Treatments Completed NCT00907257 Phase 4 benzoyl peroxide wash;Tretinoin gel
17 Tazarotene Plus Clindamycin vs. Adapalene Plus Clindamycin in the Treatment of Facial Acne Vulgaris Completed NCT02721173 Phase 4 Tazarotene 0.1% gel plus clindamycin 1% gel;Adapalene 0.1% gel plus clindamycin 1% gel
18 Treatment of Acne Vulgaris With Doryx Tablets Compared to Doxycyline Hyclate Completed NCT00635609 Phase 4 Doxycycline hyclate (Doryx);Doxycycline hyclate
19 Phase IV Study to Gather More Information About the Safety of ACZONE Gel, 5% in Treating Subjects With Acne Who Have G6PD Deficiency Completed NCT00243542 Phase 4 ACZONE Gel, 5%;Vehicle
20 A Comparative Study of the Tolerability of Two Combination Therapies for the Treatment of Acne Completed NCT00887484 Phase 4 BENZOYL PEROXIDE/ CLINDAMYCIN;BENZOYL PEROXIDE/ ADAPALENE
21 An Efficacy and Safety Study Comparing Oral Contraceptive Containing Norgestimate or Desogestrel for Acne Treatment Completed NCT01466673 Phase 4 Ethinyl estradiol/Norgestimate (EE/NGM);Ethinyl estradiol/Desogestrel (EE/DSG)
22 Comparison of Tazarotene and Minocycline Therapies for Maintenance of Facial Acne Vulgaris Completed NCT00145106 Phase 4 Tazarotene 0.1% gel + placebo capsule, Oral minocycline (100 mg capsule) + vehicle gel, Tazarotene 0.1% gel + oral minocycline (100 mg capsule)
23 Proof of Concept Study to Investigate the Recurrence of Acne Post Isotretinoin Completed NCT00939133 Phase 4 tretinoin microsphere 0.04% gel;vehicle gel
24 An Open, Non-comparative Study of the Efficacy and Safety of Treatment of Acne Scars With Restylane Vital Lidocaine Completed NCT01807455 Phase 4
25 Combination Treatment for Moderate to Severe Acne Completed NCT01206348 Phase 4 Minocycline, Clindamycin, Tretinoin, Benzoyl Peroxide
26 Effect of Samples on Acne Treatment With Epiduo® Gel Completed NCT01504204 Phase 4 Adapalene + benzoyl peroxide samples;Adapalene + benzoyl peroxide from standard tube
27 Comparison of Efficacy and Safety of Norgestimate-ethinyl Estradiol and Cyproterone Acetate-ethinyl Estradiol in the Treatment of Acne Vulgaris Completed NCT00752635 Phase 4 Norgestimate-ethinyl estradiol; Cyproterone acetate-ethinyl estradiol
28 A Study That Evaluates the Decrease in Irritation When Using Additional Acne Treatment Products Completed NCT01313728 Phase 4 Dapsone plus Tretinoin Gel;Tretinoin Gel
29 Evaluation of the Effectiveness, Safety, and Tolerability of Duac Akne Gel and Epiduo Gel in the Treatment of Facial Acne Vulgaris Completed NCT00757523 Phase 4 Epiduo Gel;Duac Gel
30 8 Week Study to Evaluate and Compare the Efficacy and Tolerability of MAXCLARITY II and MURAD To Treat Acne Completed NCT02524665 Phase 4
31 Evaluation of Efficacy and Safety of Adapalene 0.1%/Benzoyl Peroxide 2.5% Gel in the Treatment of Acne Vulgaris Completed NCT01149330 Phase 4 Adapalene-BPO Gel
32 Efficacy and Safety Study of Finacea to Treat Acne Vulgaris and Post-Inflammatory Hyperpigmentation (PIH) Completed NCT01038869 Phase 4 Azelaic acid
33 Evaluation of Quality of Life, Efficacy, and Tolerance of Duac® Gel Compared to Differin® Gel in the Treatment of Acne Completed NCT00807014 Phase 4 Duac Gel;Differin gel
34 A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Facial Acne Completed NCT00964223 Phase 4 Clindamycin and benzoyl peroxide gel (Duac® Topical Gel);benzoyl peroxide and adapalene gel (EPIDUO™ Gel)
35 Tolerability of a Foaming Facial Cleanser and Moisturizer SPF 30 in a Pediatric Population (7-11) With Acne Prone Skin. Completed NCT01909713 Phase 4 Facial Cleanser and Moisturizer SPF 30
36 Study for Long-term Treatment of Acne Vulgaris With Skinoren Versus Differin Completed NCT01387048 Phase 4 skinoren;differin;skinoren
37 Fractional CO2 Treatment of Acne Scars in Asians Completed NCT00748462 Phase 4
38 Comparison of the Efficacy and Safety of Clindamycin + Benzoyl Peroxide Formulation With Azelaic Acid Formulation in the Treatment of Acne Vulgaris Completed NCT02058628 Phase 4 Clindamycin + BPO;Azelaic acid
39 Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications Completed NCT00926367 Phase 4 Clindamycin and benzoyl peroxide;benzoyl peroxide 2.5% and adapalene 0.1% gel
40 Comparison of Duac® Gel And Differin® Gel in Mild to Moderate Acne Vulgaris Completed NCT00160394 Phase 4 Duac® Gel / Differin® Gel
41 Analysis of Adherence & Associated Factors in Teenagers Undergoing Treatment of Acne Vulgaris With Differin® Gel 0.1% Completed NCT00437151 Phase 4
42 Adapalene BPO Gel Pump, Moisturizer SPF 30 and Foam Wash in Patients With Mild to Moderate Acne Vulgaris Completed NCT01951417 Phase 4 Adapalene/BPO Gel
43 Assessment of Subjects' Efficacy and Experiences Using Adapalene BPO Gel in the Treatment of Acne Vulgaris Completed NCT01209949 Phase 4 Adapalene 0.1% and Benzoyl Peroxide 2.5% gel
44 Benzac 5% Gel in Combination With Cosmetic Products in Acne Vulgaris Completed NCT02589405 Phase 4 Benzoyl Peroxide
45 Measuring Adherence in Subjects With Acne Vulgaris in a Clinic Population Subtitle: Topical Benzoyl Peroxide for Acne Completed NCT00658112 Phase 4 Benzoyl Peroxide
46 Combination Therapy With Differin® Gel 0.3% and Duac® (Clindamycin/Benzoyl Peroxide Gel) in Subjects With Acne Vulgaris Completed NCT00671749 Phase 4 adapalene gel, 0.3%;clindamycin/benzoyl peroxide gel
47 Analysis of Adherence in Subjects Undergoing Differin Gel, 0.1% Treatment of Moderate to Severe Acne Vulgaris Completed NCT00696449 Phase 4 Adapalene
48 Injectable POLY-L-Lactic Acid for Treatment of Hill and Valley Acne Scarring Completed NCT00795327 Phase 4
49 A Five Day Clinical Study to Examine the Effects of a Benzoyl Peroxide Treatment on Facial Acne Lesions Completed NCT02052752 Phase 4 3% Benzoyl Peroxide;3% Benzoyl Peroxide Placebo;Neutrogena Rapid Clear®
50 A Phase 4, Single-Blind, Randomized, Study to Compare the Tolerability and Efficacy of 0.1% Tazorac Cream When Used in Combination With Either Duac Gel or Acanya Gel for the Treatment of Facial Acne Vulgaris Completed NCT01016977 Phase 4 Clindamycin 1%/Benzoyl Peroxide 5% and 0.1% tazarotene;clindamycin phosphate 1.2%/benzoyl peroxide 2.5% and 0.1% tazarotene

Search NIH Clinical Center for Acne

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Acne cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Acne:
Laviv azficel-T, dermal fibroblasts for scarring
Embryonic/Adult Cultured Cells Related to Acne:
Skin-derived fibroblasts PMIDs: 21287562 23211390 10805306

Genetic Tests for Acne

Genetic tests related to Acne:

id Genetic test Affiliating Genes
1 Acne 29

Anatomical Context for Acne

MalaCards organs/tissues related to Acne:

39
Skin, Ovary, Testes, Brain, Lung, Colon, Eye

Publications for Acne

Articles related to Acne:

(show top 50) (show all 1149)
id Title Authors Year
1
A peel-off facial mask comprising myoinositol and trehalose-loaded liposomes improves adult female acne by reducing local hyperandrogenism and activating autophagy. ( 28342238 )
2017
2
Phenotype and antimicrobial activity of Th17 cells induced by Propionibacterium acnes strains associated with healthy and acne skin. ( 28864077 )
2017
3
Acne keloidalis nuchae: clinical and dermoscopic features. ( 28942416 )
2017
4
Generic, twice-daily minocycline versus branded, extended-release minocycline for acne: A retrospective comparison of treatment escalation. ( 28522046 )
2017
5
Propionibacterium acnes-associated neurosarcoidosis: A case report with review of the literature. ( 28856748 )
2017
6
A Retrospective Study of Multiple Sequential Light and Laser Sources to Activate Aminolevulinic Acid in the Treatment of Acne Vulgaris. ( 28528603 )
2017
7
Development of an atrophic acne scar risk assessment tool. ( 28499079 )
2017
8
Comparison of salicylic acid 30% peel and pneumatic broadband light in the treatment of mild to moderately severe facial acne vulgaris. ( 28873106 )
2017
9
Ipsilateral facial paralysis and steroid acne. ( 28366909 )
2017
10
Edible Plants and Their Influence on the Gut Microbiome and Acne. ( 28513546 )
2017
11
Immunohistochemical identification of Propionibacterium acnes in granuloma and inflammatory cells of myocardial tissues obtained from cardiac sarcoidosis patients. ( 28686683 )
2017
12
Adherence to over-the-counter benzoyl peroxide in patients with acne. ( 28917458 )
2017
13
A case of bronchiolitis obliterans organising pneumonia associated with SAPHO (synovitis-acne-pustulosis-hyperostosis-osteitis) syndrome. ( 28765183 )
2017
14
Spironolactone for the Treatment of Acne: A 4-Year Retrospective Study. ( 28472793 )
2017
15
The Use of Cosmeceuticals in Acne: Help or Hoax? ( 28063095 )
2017
16
Qualitative study of online discussion forums about acne. ( 28940278 )
2017
17
Non-ablative fractional laser-assisted daylight photodynamic therapy with topical methyl aminolevulinate for moderate to severe facial acne vulgaris: Results of a randomized and comparative study. ( 28500784 )
2017
18
Pulsed radiofrequency or anterior neurectomy for anterior cutaneous nerve entrapment syndrome (ACNES) (the PULSE trial): study protocol of a randomized controlled trial. ( 28768538 )
2017
19
Successful therapy of excoriated acne with Nd:YAG laser: a case report. ( 28941267 )
2017
20
Randomized, controlled trial split-faced study of 595-nm pulsed dye laser in the treatment of acne vulgaris and acne erythema in adolescents and early adulthood. ( 28447362 )
2017
21
A Review of hormone-based therapies to treat adult acne vulgaris in women. ( 28492054 )
2017
22
Propionibacterium acnes endocarditis: a case series. ( 28057559 )
2017
23
Acne necrotica (necrotizing lymphocytic folliculitis): An enigmatic and under-recognised dermatosis. ( 28240342 )
2017
24
The colonisation of the glenohumeral joint by Propionibacterium acnes is not associated with frozen shoulder but is more likely to occur after an injection into the joint. ( 28768784 )
2017
25
An ecofriendly green liquid chromatographic method for simultaneous determination of nicotinamide and clindamycin phosphate in pharmaceutical gel for acne treatment. ( 28911660 )
2017
26
Are normal serum levels of insulin-like growth factor-1 clinically relevant in acne? ( 28522070 )
2017
27
Modern management of acne. ( 28076744 )
2017
28
Propionibacterium acnes pleural empyema following medical thoracoscopy. ( 28638619 )
2017
29
Psychological Status and Quality of Life in Acne Patients Treated with Oral Isotretinoin. ( 28492216 )
2017
30
Teens and Technology Transforming Acne Treatment. ( 28898196 )
2017
31
Comparative Effects of Schisandrin A, B, and C on Acne-Related Inflammation. ( 28875271 )
2017
32
Reconsidering Accuracy of Acne Self-Reports. ( 28903585 )
2017
33
Acne conglobata in a long-term survivor with trisomy 13, accompanied by selective IgM deficiency. ( 28480529 )
2017
34
Combined Fractional Treatment of Acne Scars Involving Non-ablative 1,550-nm Erbium-glass Laser and Micro-needling Radiofrequency: A 16-week Prospective, Randomized Split-face Study. ( 28512669 )
2017
35
Multiple Activities of Punica granatum Linne against Acne Vulgaris. ( 28085116 )
2017
36
Acne Scars: How Do We Grade Them? ( 28891036 )
2017
37
Recognition of Propionibacterium acnes by human TLR2 heterodimers. ( 28024924 )
2017
38
Fractional Erbium-Doped Yttrium Aluminum Garnet Laser Versus Microneedling in Treatment of Atrophic Acne Scars: A Randomized Split-Face Clinical Study. ( 28009690 )
2017
39
The Role of Skin Care in Optimizing Treatment of Acne and Rosacea. ( 28492949 )
2017
40
The Impact of Pyschological Stress on Acne. ( 28871928 )
2017
41
Treatment of Acne Scars on Darker Skin Types Using a Noninsulated Smooth Motion, Electronically Controlled Radiofrequency Microneedles Treatment System. ( 28009691 )
2017
42
SAPHO Syndrome: Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis. ( 28250311 )
2017
43
B cell cross-epitope of Propionibacterium acnes and Actinobacillus pleuropneumonia selected by phage display library can efficiently protect from Actinobacillus pleuropneumonia infection. ( 28622855 )
2017
44
PSENEN Mutation Carriers with Co-manifestation of Acne Inversa (AI) andA Dowling-Degos Disease (DDD): IsA AIA orA DDD the Subphenotype? ( 28601418 )
2017
45
Quality of Life Measurement in Acne. Position Paper of the European Academy of Dermatology and Venereology (EADV) Task Forces on Quality of Life and Patient Oriented Outcomes (QoL and PO) and Acne, Rosacea and Hidradenitis Suppurativa (ARHS). ( 28898474 )
2017
46
International inter-rater agreement in scoring acne severity utilizing cloud-based image sharing of mobile phone photographs. ( 28436531 )
2017
47
Relationship between acne vulgaris and cosmetic usage in Sri Lankan urban adolescent females. ( 28941014 )
2017
48
Acute Appendicitis, Somatosensory Disturbances ("Head Zones"), and the Differential Diagnosis of Anterior Cutaneous Nerve Entrapment Syndrome (ACNES). ( 28411350 )
2017
49
Fractional carbon dioxide laser for the treatment of facial atrophic acne scars: prospective clinical trial with short and long-term evaluation. ( 28894992 )
2017
50
Factors affecting the course and severity of adult acne. Observational cohort study. ( 28489484 )
2017

Variations for Acne

Expression for Acne

Search GEO for disease gene expression data for Acne.

Pathways for Acne

GO Terms for Acne

Cellular components related to Acne according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.85 CAT CXCL8 DEFB1 DEFB4A FGFR2 IL1A
2 extracellular space GO:0005615 9.61 CAT CXCL8 DEFB1 DEFB4A GGT1 IL1A
3 gamma-secretase complex GO:0070765 8.8 NCSTN PSEN1 PSENEN

Biological processes related to Acne according to GeneCards Suite gene sharing:

(show all 23)
id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.91 CXCL8 IL1A IL1RN PSTPIP1 TLR2
2 immune response GO:0006955 9.85 CXCL8 DEFB1 DEFB4A IL1A IL1RN TLR2
3 defense response to Gram-positive bacterium GO:0050830 9.75 DEFB1 DEFB4A TLR2
4 positive regulation of catalytic activity GO:0043085 9.73 NCSTN PSEN1 PSENEN
5 response to ethanol GO:0045471 9.71 CAT FGFR2 G6PD RBP4
6 protein processing GO:0016485 9.7 NCSTN PSEN1 PSENEN
7 positive regulation of cell division GO:0051781 9.67 CAT FGFR2 IL1A
8 membrane protein intracellular domain proteolysis GO:0031293 9.61 NCSTN PSENEN
9 response to fatty acid GO:0070542 9.61 CAT TLR2
10 response to hyperoxia GO:0055093 9.6 CAT CYP1A1
11 response to toxic substance GO:0009636 9.59 CAT TLR2
12 leukotriene metabolic process GO:0006691 9.58 GGT1 TLR2
13 beta-amyloid metabolic process GO:0050435 9.57 NCSTN PSEN1
14 epithelial cell proliferation GO:0050673 9.55 NCSTN PSEN1
15 response to molecule of bacterial origin GO:0002237 9.54 CXCL8 TLR2
16 membrane protein ectodomain proteolysis GO:0006509 9.5 NCSTN PSEN1 PSENEN
17 embryonic organ morphogenesis GO:0048562 9.48 FGFR2 RBP4
18 response to iron(III) ion GO:0010041 9.43 CYP1A1 G6PD
19 Notch receptor processing GO:0007220 9.43 NCSTN PSEN1 PSENEN
20 amyloid precursor protein metabolic process GO:0042982 9.33 NCSTN PSEN1 PSENEN
21 fever generation GO:0001660 9.16 IL1A
22 amyloid precursor protein catabolic process GO:0042987 9.13 NCSTN PSEN1 PSENEN
23 beta-amyloid formation GO:0034205 8.8 NCSTN PSEN1 PSENEN

Molecular functions related to Acne according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.55 ALPP CXCL8 CYP1A1 DEFB1 DEFB4A FGFR2
2 interleukin-1 receptor binding GO:0005149 9.16 IL1A IL1RN
3 CCR6 chemokine receptor binding GO:0031731 8.96 DEFB1 DEFB4A

Sources for Acne

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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