Aliases & Classifications for Acne

Aliases & Descriptions for Acne:

Name: Acne 38 12 41 14 69
Acne Vulgaris 12 52 14 69
Acne Varioliformis 12 69
Frontalis Acne 12
Acnes 29

Classifications:



Summaries for Acne

MedlinePlus : 41 acne is a common skin disease that causes pimples. pimples form when hair follicles under your skin clog up. most pimples form on the face, neck, back, chest, and shoulders. anyone can get acne, but it is common in teenagers and young adults. it is not serious, but it can cause scars. no one knows exactly what causes acne. hormone changes, such as those during the teenage years and pregnancy, probably play a role. there are many myths about what causes acne. chocolate and greasy foods are often blamed, but there is little evidence that foods have much effect on acne in most people. another common myth is that dirty skin causes acne; however, blackheads and pimples are not caused by dirt. stress doesn't cause acne, but stress can make it worse. if you have acne clean your skin gently try not to touch your skin avoid the sun treatments for acne include medicines and creams. nih: national institute of arthritis and musculoskeletal and skin diseases

MalaCards based summary : Acne, also known as acne vulgaris, is related to skin conditions and retinal dystrophy, iris coloboma, and comedogenic acne syndrome, and has symptoms including exanthema and pruritus. An important gene associated with Acne is NCSTN (Nicastrin), and among its related pathways/superpathways are Innate Immune System and Folate Metabolism. The drugs Benzoyl peroxide and Clindamycin have been mentioned in the context of this disorder. Affiliated tissues include skin, ovary and monocytes, and related phenotypes are Increased shRNA abundance and cardiovascular system

Disease Ontology : 12 A sebaceous gland disease characterized by areas of blackheads, whiteheads, pimples, greasy skin, and possibly scarring.

Wikipedia : 71 Acne, also known as acne vulgaris, is a long-term skin disease that occurs when hair follicles are... more...

Related Diseases for Acne

Diseases related to Acne via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 239)
id Related Disease Score Top Affiliating Genes
1 skin conditions 31.3 CXCL8 IL1A IL1RN
2 retinal dystrophy, iris coloboma, and comedogenic acne syndrome 12.2
3 acne inversa, familial, 3 12.1
4 acne inversa, familial, 1 12.1
5 acne inversa, familial, 2 12.1
6 pyogenic sterile arthritis, pyoderma gangrenosum, and acne 12.0
7 pyogenic arthritis, pyoderma gangrenosum and acne 12.0
8 hidradenitis suppurativa 11.8
9 sapho syndrome 11.7
10 pyoderma gangrenosum-acne-suppurative hidradenitis syndrome 11.7
11 rosacea 11.6
12 anterior cutaneous nerve entrapment syndrome 11.5
13 polycystic ovary syndrome 11.3
14 dowling-degos disease 11.2
15 hyperandrogenism 11.0
16 granulomatous rosacea 11.0
17 keratosis pilaris 11.0
18 isotretinoin syndrome 10.8
19 polydactyly, postaxial, types a1 and b 10.7
20 diabetes mellitus, insulin-resistant, with acanthosis nigricans 10.6
21 luteoma 10.6
22 urbach-wiethe disease 10.6
23 darier disease 10.6
24 fetal retinoid syndrome 10.6
25 cushing's syndrome 10.6
26 perifolliculitis capitis abscedens et suffodiens, familial 10.6
27 central precocious puberty 10.6
28 hair-an syndrome 10.6
29 familial male-limited precocious puberty 10.6
30 hyperadrenalism 10.6
31 aromatase deficiency 10.6
32 frank-ter haar syndrome 10.6
33 nevus comedonicus 10.6
34 adrenal hyperplasia, congenital, due to 21-hydroxylase deficiency 10.6
35 hidradenitis 10.3
36 myeloid proliferations related to down syndrome 10.3 CXCL8 TLR2
37 synovitis 10.3
38 hyperostosis 10.3
39 autosomal recessive type iv ehlers-danlos syndrome 10.2 CXCL8 IL1A IL1RN
40 nemaline myopathy 1, autosomal dominant or recessive 10.2 IL1RN NCSTN PSENEN PSTPIP1
41 scleroperikeratitis 10.2 IL1RN NCSTN PSENEN PSTPIP1
42 myoclonic astatic epilepsy 10.2 CXCL8 TLR2
43 classic type lipoma 10.2 CXCL8 IL1A IL1RN
44 baritosis 10.2 CAT CXCL8 IL1A
45 parasitic protozoa infectious disease 10.2 CXCL8 FLG IL1A
46 chilblain lupus 2 10.1 ALOX5 G6PD GGT1
47 malignant histiocytosis 10.1 CXCL8 ITGB2 PSTPIP1
48 histiocytoma 10.1 CXCL8 ITGB2 PSTPIP1
49 pyoderma 10.1
50 nasopharyngitis 10.1 CXCL8 DEFB1 IL1A

Graphical network of the top 20 diseases related to Acne:



Diseases related to Acne

Symptoms & Phenotypes for Acne

UMLS symptoms related to Acne:


exanthema, pruritus

GenomeRNAi Phenotypes related to Acne according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance GR00327-A 9.1 CAT CYP1A1 DEFB1 FGFR2 G6PD IL1RN

MGI Mouse Phenotypes related to Acne:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 ALOX5 CYP1A1 FGFR2 G6PD IL1A IL1RN
2 hematopoietic system MP:0005397 9.9 ALOX5 CYP1A1 FGFR2 G6PD GGT1 IL1A
3 immune system MP:0005387 9.7 ITGB2 NCSTN PSTPIP1 TLR2 XDH ALOX5
4 integument MP:0010771 9.23 FGFR2 GGT1 IL1A IL1RN ITGB2 NCSTN

Drugs & Therapeutics for Acne

Drugs for Acne (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 383)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzoyl peroxide Approved Phase 4,Phase 3,Phase 1,Phase 2 94-36-0 7187
2
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 18323-44-9 29029
3
Lymecycline Approved Phase 4,Phase 3 992-21-2 5280963
4
Minocycline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 10118-90-8 5281021
5
Adapalene Approved Phase 4,Phase 3,Phase 2,Phase 1 106685-40-9 60164
6
Ciclopirox Approved, Investigational Phase 4 29342-05-0 2749
7
Isotretinoin Approved Phase 4,Phase 3,Phase 2,Phase 1 4759-48-2 5538 5282379
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 22916-47-8 4189
9
Salicylic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 69-72-7 338
10
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 564-25-0 54671203
11
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-28-2 5757 53477783
12
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2,Phase 1 57-63-6 5991
13
Azelaic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 123-99-9 2266
14
Dapsone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 80-08-0 2955
15
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 1 9004-61-9 53477741 24759
16
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
17
Drospirenone Approved Phase 4,Phase 3,Phase 2 67392-87-4 68873
18
Aminolevulinic acid Approved Phase 4,Phase 2,Phase 1 106-60-5 137
19
Tazarotene Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 118292-40-3 5381
20
Cyproterone Acetate Approved, Investigational Phase 4,Phase 3 427-51-0
21
Moxifloxacin Approved, Investigational Phase 4,Phase 1 354812-41-2, 151096-09-2 152946
22
Norgestimate Approved Phase 4,Phase 1 35189-28-7 6540478
23
Norgestrel Approved Phase 4 6533-00-2 13109
24
Desogestrel Approved Phase 4 54024-22-5 40973
25
Benzocaine Approved Phase 4,Phase 2 1994-09-7, 94-09-7 2337
26
Coal tar Approved Phase 4,Phase 1 8007-45-2
27
Prilocaine Approved Phase 4 721-50-6 4906
28
Tetracaine Approved, Vet_approved Phase 4 94-24-6 5411
29
Metformin Approved Phase 4,Phase 3 657-24-9 14219 4091
30
Desonide Approved, Investigational Phase 4 638-94-8 5311066
31
Hydroxocobalamin Approved Phase 4 13422-51-0 11953898 5460373 44475014
32
Ethanol Approved Phase 4,Phase 2 64-17-5 702
33
Glycerol Approved, Experimental Phase 4 56-81-5 753
34
Polidocanol Approved Phase 4 9002-92-0
35
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
36
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
37
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
38
Mycophenolic acid Approved Phase 4 24280-93-1 446541
39
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
40
Azathioprine Approved Phase 4 446-86-6 2265
41
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
42
Tretinoin Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 302-79-4 5538
43
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 59-30-3 6037
44
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 58-05-9 54575, 6560146 143
45
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4 59-02-9 14985
46
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 59-67-6 938
47
Nicotinamide Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 98-92-0 936
48 tannic acid Approved, Nutraceutical Phase 4,Phase 2
49
Cyanocobalamin Approved, Nutraceutical Phase 4 68-19-9 44176380
50
Manganese Approved, Nutraceutical Phase 4 7439-96-5 27854

Interventional clinical trials:

(show top 50) (show all 567)
id Name Status NCT ID Phase
1 Safety and Tolerability of Acanya Gel in Combination With Atralin Gel for Acne Vulgaris Unknown status NCT01448733 Phase 4
2 A Study Comparing Combination Clindamycin Phosphate/Tretinoin Gel Alone Versus With Benzoyl Peroxide Foaming Cloths for Facial Acne Unknown status NCT01422785 Phase 4
3 Clinical Study to Evaluate the Efficacy of Topical Medications Containing Benzoyl Peroxide and Sulfur in the Regression in the Short Time (24 Hours) of Moderate Acne Vulgaris Grade II (Pimples) Unknown status NCT01260571 Phase 4
4 Efficacy & Safety of Clindamycin and Tretinoin in Acne Unknown status NCT01111994 Phase 4
5 Safety and Efficacy Comparison of Minocycline Microgranules Versus Lymecycline in the Treatment of Mild to Moderate Acne Unknown status NCT00988026 Phase 4
6 Control of Therapy of Acne Papulopustulosa by Visible Light With Waterfiltered Infrared and / or Adapalen (Differin Gel) Unknown status NCT00237978 Phase 4
7 Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea Unknown status NCT01139749 Phase 4
8 VSL#3 Treatment in Children With Crohn's Disease Unknown status NCT00367705 Phase 4
9 Adherence to Study Medication Compared to Generic Topical Clindamycin Plus Generic Topical Tretinoin in Subjects With Mild to Moderate Acne Vulgaris Completed NCT01047189 Phase 4
10 A Treatment Regimen for Student Athletes With Mild to Moderate Acne Vulgaris Completed NCT02249104 Phase 4
11 Evaluation of the Effectiveness, Safety, and Tolerability of Duac Akne Gel and Epiduo Gel in the Treatment of Facial Acne Vulgaris Completed NCT00757523 Phase 4
12 Treatment of Acne Vulgaris With Doryx Tablets Compared to Doxycyline Hyclate Completed NCT00635609 Phase 4
13 Tazarotene Plus Clindamycin vs. Adapalene Plus Clindamycin in the Treatment of Facial Acne Vulgaris Completed NCT02721173 Phase 4
14 Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Facial Acne Completed NCT00841776 Phase 4
15 Anti Propionibacterium(P.) Acnes Activity of Epiduo® Gel Compared to Benzoyl Peroxide (BPO) 2.5% Gel Completed NCT01188538 Phase 4
16 Comparison of Efficacy and Safety of Norgestimate-ethinyl Estradiol and Cyproterone Acetate-ethinyl Estradiol in the Treatment of Acne Vulgaris Completed NCT00752635 Phase 4
17 Comparison Study of Topical Acne Regimens Completed NCT00913185 Phase 4
18 Evaluation of Efficacy and Safety of Adapalene 0.1%/Benzoyl Peroxide 2.5% Gel in the Treatment of Acne Vulgaris Completed NCT01149330 Phase 4
19 A Comparative Study of the Tolerability of Two Combination Therapies for the Treatment of Acne Completed NCT00887484 Phase 4
20 Study for Long-term Treatment of Acne Vulgaris With Skinoren Versus Differin Completed NCT01387048 Phase 4
21 A Study of Different Use Regimens Using Two Acne Treatments Completed NCT00907257 Phase 4
22 Comparison of Tazarotene and Minocycline Therapies for Maintenance of Facial Acne Vulgaris Completed NCT00145106 Phase 4
23 Phase IV Study to Gather More Information About the Safety of ACZONE Gel, 5% in Treating Subjects With Acne Who Have G6PD Deficiency Completed NCT00243542 Phase 4
24 Comparison of the Efficacy and Safety of Clindamycin + Benzoyl Peroxide Formulation With Azelaic Acid Formulation in the Treatment of Acne Vulgaris Completed NCT02058628 Phase 4
25 Efficacy and Safety Study of Finacea to Treat Acne Vulgaris and Post-Inflammatory Hyperpigmentation (PIH) Completed NCT01038869 Phase 4
26 Comparison of Duac® Gel And Differin® Gel in Mild to Moderate Acne Vulgaris Completed NCT00160394 Phase 4
27 Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne Completed NCT00837213 Phase 4
28 A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Facial Acne Completed NCT00964223 Phase 4
29 Evaluation of Quality of Life, Efficacy, and Tolerance of Duac® Gel Compared to Differin® Gel in the Treatment of Acne Completed NCT00807014 Phase 4
30 Assessment of Subjects' Efficacy and Experiences Using Adapalene BPO Gel in the Treatment of Acne Vulgaris Completed NCT01209949 Phase 4
31 Combination Therapy With Differin® Gel 0.3% and Duac® (Clindamycin/Benzoyl Peroxide Gel) in Subjects With Acne Vulgaris Completed NCT00671749 Phase 4
32 An Efficacy and Safety Study Comparing Oral Contraceptive Containing Norgestimate or Desogestrel for Acne Treatment Completed NCT01466673 Phase 4
33 A Phase 4, Single-Blind, Randomized, Study to Compare the Tolerability and Efficacy of 0.1% Tazorac Cream When Used in Combination With Either Duac Gel or Acanya Gel for the Treatment of Facial Acne Vulgaris Completed NCT01016977 Phase 4
34 Benzac 5% Gel in Combination With Cosmetic Products in Acne Vulgaris Completed NCT02589405 Phase 4
35 Measuring Adherence in Subjects With Acne Vulgaris in a Clinic Population Subtitle: Topical Benzoyl Peroxide for Acne Completed NCT00658112 Phase 4
36 Analysis of Adherence in Subjects Undergoing Differin Gel, 0.1% Treatment of Moderate to Severe Acne Vulgaris Completed NCT00696449 Phase 4
37 A Study of Dapsone Gel in Females With Skin of Color and Acne Vulgaris Completed NCT02032407 Phase 4
38 Effect of Samples on Acne Treatment With Epiduo® Gel Completed NCT01504204 Phase 4
39 A Study That Evaluates the Decrease in Irritation When Using Additional Acne Treatment Products Completed NCT01313728 Phase 4
40 8 Week Study to Evaluate and Compare the Efficacy and Tolerability of MAXCLARITY II and MURAD To Treat Acne Completed NCT02524665 Phase 4
41 Analysis of Adherence & Associated Factors in Teenagers Undergoing Treatment of Acne Vulgaris With Differin® Gel 0.1% Completed NCT00437151 Phase 4
42 Adapalene BPO Gel Pump, Moisturizer SPF 30 and Foam Wash in Patients With Mild to Moderate Acne Vulgaris Completed NCT01951417 Phase 4
43 Aczone 5% Gel as Maintenance Treatment of Acne Vulgaris Following Completion of Oral Doxycycline and Aczone 5% Gel Completed NCT01885910 Phase 4
44 Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications Completed NCT00926367 Phase 4
45 A Study Comparing Aczone® Plus Differin® Versus Duac® Plus Differin® in Patients With Severe Facial Acne Completed NCT01231334 Phase 4
46 DUAC® Early Onset Efficacy Study in Japanese Subjects Completed NCT02557399 Phase 4
47 Injectable POLY-L-Lactic Acid for Treatment of Hill and Valley Acne Scarring Completed NCT00795327 Phase 4
48 U0289-402: An Open Label, 8 Week Study to Evaluate the Efficacy and Tolerability of MAXCLARITY II in Subjects With Acne Completed NCT01706263 Phase 4
49 Proof of Concept Study to Investigate the Recurrence of Acne Post Isotretinoin Completed NCT00939133 Phase 4
50 Differin® Gel x12 Wks vs Tazorac® Cream x12 Wks vs Differin® x6 Wks Switched to Tazorac® x6 Wks for Treatment of Acne Completed NCT00469755 Phase 4

Search NIH Clinical Center for Acne

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Acne cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Acne:
Laviv azficel-T, dermal fibroblasts for scarring
Embryonic/Adult Cultured Cells Related to Acne:
Skin-derived fibroblasts PMIDs: 21287562 23211390 10805306

Genetic Tests for Acne

Genetic tests related to Acne:

id Genetic test Affiliating Genes
1 Acne 29

Anatomical Context for Acne

MalaCards organs/tissues related to Acne:

39
Skin, Ovary, Monocytes, Neutrophil, Bone, Brain, Testes

Publications for Acne

Articles related to Acne:

(show top 50) (show all 1110)
id Title Authors Year
1
Chocolate Consumption May Make Acne Vulgaris Worse. ( 28084699 )
2017
2
Multiple Activities of Punica granatum Linne against Acne Vulgaris. ( 28085116 )
2017
3
Modern management of acne. ( 28076744 )
2017
4
Combined Fractional Treatment of Acne Scars Involving Non-ablative 1,550-nm Erbium-glass Laser and Micro-needling Radiofrequency: A 16-week Prospective, Randomized Split-face Study. ( 28512669 )
2017
5
Non-ablative fractional laser-assisted daylight photodynamic therapy with topical methyl aminolevulinate for moderate to severe facial acne vulgaris: Results of a randomized and comparative study. ( 28500784 )
2017
6
Are normal serum levels of insulin-like growth factor-1 clinically relevant in acne? ( 28522070 )
2017
7
International inter-rater agreement in scoring acne severity utilizing cloud-based image sharing of mobile phone photographs. ( 28436531 )
2017
8
Acne conglobata induced by adalimumab. ( 28524046 )
2017
9
Psychological Status and Quality of Life in Acne Patients Treated with Oral Isotretinoin. ( 28492216 )
2017
10
Randomized, controlled trial split-faced study of 595-nm pulsed dye laser in the treatment of acne vulgaris and acne erythema in adolescents and early adulthood. ( 28447362 )
2017
11
Recognition of Propionibacterium acnes by human TLR2 heterodimers. ( 28024924 )
2017
12
Propionibacterium acnes endocarditis: a case series. ( 28057559 )
2017
13
Factors affecting the course and severity of adult acne. Observational cohort study. ( 28489484 )
2017
14
Prioritizing treatment outcomes: How people with acne vulgaris decide if their treatment is working. ( 28444879 )
2017
15
Evolution of some indicators of systemic immunity in patients with acne while using laser therapy. ( 28511158 )
2017
16
Acne conglobata in a long-term survivor with trisomy 13, accompanied by selective IgM deficiency. ( 28480529 )
2017
17
Identifying what to measure in acne clinical trials: first steps towards development of a core outcome set. ( 28457913 )
2017
18
Chemical pharmacotherapy options for managing adult acne. ( 28081648 )
2017
19
A Review of hormone-based therapies to treat adult acne vulgaris in women. ( 28492054 )
2017
20
Generic, twice-daily minocycline versus branded, extended-release minocycline for acne: A retrospective comparison of treatment escalation. ( 28522046 )
2017
21
Edible Plants and Their Influence on the Gut Microbiome and Acne. ( 28513546 )
2017
22
Development of an atrophic acne scar risk assessment tool. ( 28499079 )
2017
23
Fractional Erbium-Doped Yttrium Aluminum Garnet Laser Versus Microneedling in Treatment of Atrophic Acne Scars: A Randomized Split-Face Clinical Study. ( 28009690 )
2017
24
The Role of Skin Care in Optimizing Treatment of Acne and Rosacea. ( 28492949 )
2017
25
A Retrospective Study of Multiple Sequential Light and Laser Sources to Activate Aminolevulinic Acid in the Treatment of Acne Vulgaris. ( 28528603 )
2017
26
Treatment of Acne Scars on Darker Skin Types Using a Noninsulated Smooth Motion, Electronically Controlled Radiofrequency Microneedles Treatment System. ( 28009691 )
2017
27
The Use of Cosmeceuticals in Acne: Help or Hoax? ( 28063095 )
2017
28
Spironolactone for the Treatment of Acne: A 4-Year Retrospective Study. ( 28472793 )
2017
29
Pyoderma Gangrenosum, Acne and Suppurative Hidradenitis Syndrome Treated with Granulocyte and Monocyte Adsorption Apheresis. ( 27384061 )
2016
30
A consensus-based practical and daily guide for the treatment of acne patients. ( 27177989 )
2016
31
Translation, cultural adaptation and validation for Brazilian Portuguese of the Cardiff Acne Disability Index instrument. ( 27192517 )
2016
32
Imaging for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome. ( 27742022 )
2016
33
Nicastrin mutations in familial acne inversa impact keratinocyte proliferation and differentiation through the Notch and phosphoinositide 3-kinase/AKT signalling pathways. ( 26473517 )
2016
34
Relationship between acne vulgaris and attention-deficit/hyperactivity disorder symptoms in a clinical sample of women. ( 27192533 )
2016
35
When inflammation shifts to malignancy: extensive squamous cell carcinoma in a female hidradenitis suppurativa/acne inversa patient. ( 28036145 )
2016
36
Resistin gene polymorphisms are associated with acne and serum lipid levels, providing a potential nexus between lipid metabolism and inflammation. ( 26858108 )
2016
37
The development and validation of an acne self-regulation inventory. ( 27568919 )
2016
38
The Role of Blood Lead, Cadmium, Zinc and Copper in Development and Severity of Acne Vulgaris in a Nigerian Population. ( 27600928 )
2016
39
High level of serum human interleukin-18 in a patient with pyogenic arthritis, pyoderma gangrenosum and acne syndrome. ( 27505688 )
2016
40
Efficacy and Safety of Once-Daily Dapsone Gel, 7.5% for Treatment of Adolescents and Adults With Acne Vulgaris: First of Two Identically Designed, Large, Multicenter, Randomized, Vehicle-controlled Trials. ( 27168264 )
2016
41
Which treatment options do acne patients prefer? ( 28036131 )
2016
42
Oral clindamycin and rifampicin in the treatment of hidradenitis suppurativa-acne inversa: can some factors influence the response to the treatment? ( 27068603 )
2016
43
Acne keloidalis nuchae: prevalence, impact, and management challenges. ( 28008278 )
2016
44
Ocular acne rosacea in tertiary eye center in Saudi Arabia. ( 28039671 )
2016
45
Supplementation with Lactobacillus rhamnosus SP1 normalises skin expression of genes implicated in insulin signalling and improves adult acne. ( 27596801 )
2016
46
Olumacostat glasaretil, a novel topical sebum inhibitor, in the treatment of acne vulgaris: A phase IIa, multicenter, randomized, vehicle-controlled study. ( 28029390 )
2016
47
a8-a8-a8-a8-a8-a8-a8-a8-Development and characterization of polymeric nanoparticle-based formulation of adapalene for topical acne therapya8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-a8-. ( 27565687 )
2016
48
Comparison effect of azithromycin gel 2% with clindamycin gel 1% in patients with acne. ( 27169103 )
2016
49
Efficacy and safety of 1550nm fractional photothermolysis in the treatment of acne scars in Chinese patients: A split face comparative study. ( 27183153 )
2016
50
Characterization of a Novel Mutation in the NCSTN Gene in a Large Chinese Family with Acne Inversa. ( 26463457 )
2016

Variations for Acne

Expression for Acne

Search GEO for disease gene expression data for Acne.

Pathways for Acne

GO Terms for Acne

Cellular components related to Acne according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 ALOX5 CAT CXCL8 DEFB1 DEFB4A FGFR2
2 extracellular space GO:0005615 9.28 ALOX5 CAT CXCL8 DEFB1 DEFB4A GGT1
3 gamma-secretase complex GO:0070765 9.16 NCSTN PSENEN

Biological processes related to Acne according to GeneCards Suite gene sharing:

(show all 17)
id Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.88 ALOX5 CAT ITGB2 NCSTN TLR2
2 positive regulation of angiogenesis GO:0045766 9.74 CXCL8 IL1A ITGB2
3 immune response GO:0006955 9.63 CXCL8 DEFB1 DEFB4A IL1A IL1RN TLR2
4 defense response to Gram-positive bacterium GO:0050830 9.61 DEFB1 DEFB4A TLR2
5 membrane protein intracellular domain proteolysis GO:0031293 9.56 NCSTN PSENEN
6 response to fatty acid GO:0070542 9.55 CAT TLR2
7 response to hyperoxia GO:0055093 9.54 CAT CYP1A1
8 positive regulation of cell division GO:0051781 9.54 CAT FGFR2 IL1A
9 Notch receptor processing GO:0007220 9.52 NCSTN PSENEN
10 purine nucleotide catabolic process GO:0006195 9.51 CAT XDH
11 response to molecule of bacterial origin GO:0002237 9.49 CXCL8 TLR2
12 amyloid precursor protein metabolic process GO:0042982 9.46 NCSTN PSENEN
13 amyloid precursor protein catabolic process GO:0042987 9.4 NCSTN PSENEN
14 beta-amyloid formation GO:0034205 9.32 NCSTN PSENEN
15 response to iron(III) ion GO:0010041 9.26 CYP1A1 G6PD
16 inflammatory response GO:0006954 9.17 ALOX5 CXCL8 IL1A IL1RN ITGB2 PSTPIP1
17 leukotriene metabolic process GO:0006691 9.13 ALOX5 GGT1 TLR2

Molecular functions related to Acne according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.89 ALOX5 ALPP CXCL8 CYP1A1 DEFB1 DEFB4A
2 interleukin-1 receptor binding GO:0005149 9.16 IL1A IL1RN
3 CCR6 chemokine receptor binding GO:0031731 8.62 DEFB1 DEFB4A

Sources for Acne

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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