MCID: ACS001
MIFTS: 57

Acoustic Neuroma malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases, Immune diseases

Aliases & Classifications for Acoustic Neuroma

About this section
Sources:
11Disease Ontology, 13DISEASES, 26GTR, 30ICD10 via Orphanet, 37MedlinePlus, 38MeSH, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Acoustic Neuroma:

Name: Acoustic Neuroma 11 47 53 37 13 67
Vestibular Schwannoma 11 47 53 26
Cerebellopontine Angle Tumor 47 67
Acoustic Neurilemoma 47 53
Acoustic Neurinoma 47 53
 
Neurinoma of the Acoustic Nerve 47
Vestibular Neurilemmoma 11
Neuroma, Acoustic 38
Neuroma Acoustic 49
Acoustic Tumor 47

Characteristics:

Orphanet epidemiological data:

53
acoustic neuroma:
Prevalence: 1-9/100000 (Denmark),1-9/100000 (United States),1-9/1000000

Classifications:



External Ids:

Disease Ontology11 DOID:12689
MeSH38 D009464
NCIt44 C3276
Orphanet53 ORPHA252175
UMLS via Orphanet68 C0027859
ICD10 via Orphanet30 D33.3

Summaries for Acoustic Neuroma

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MedlinePlus:37 An acoustic neuroma is a benign tumor that develops on the nerve that connects the ear to the brain. the tumor usually grows slowly. as it grows, it presses against the hearing and balance nerves. at first, you may have no symptoms or mild symptoms. they can include loss of hearing on one side ringing in ears dizziness and balance problems the tumor can also eventually cause numbness or paralysis of the face. if it grows large enough, it can press against the brain, becoming life-threatening. acoustic neuroma can be difficult to diagnose, because the symptoms are similar to those of middle ear problems. ear exams, hearing tests, and scans can show if you have it. if the tumor stays small, you may only need to have it checked regularly. if you do need treatment, surgery and radiation are options. if the tumors affect both hearing nerves, it is often because of a genetic disorder called neurofibromatosis. nih: national institute on deafness and communication disorders

MalaCards based summary: Acoustic Neuroma, also known as vestibular schwannoma, is related to cerebellopontine angle tumor and neurofibromatosis, type 2, and has symptoms including back pain, coughing and headache. An important gene associated with Acoustic Neuroma is NF2 (Neurofibromin 2), and among its related pathways are BARD1 signaling events and Spinal Cord Injury. Affiliated tissues include brain, testes and bone, and related mouse phenotypes are neoplasm and reproductive system.

Wikipedia:70 A vestibular schwannoma is a benign primary intracranial tumor of the myelin-forming cells of the... more...

Related Diseases for Acoustic Neuroma

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Diseases related to Acoustic Neuroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 67)
idRelated DiseaseScoreTop Affiliating Genes
1cerebellopontine angle tumor12.3
2neurofibromatosis, type 212.1
3neuroma11.1
4neurofibromatosis, type 111.1
5schwannomatosis10.9
6urinary schistosomiasis10.4NF2, TGFB1
7central centrifugal cicatricial alopecia10.3MGMT, NF2
8hepatic osteogenic sarcoma10.3AQP1, AQP4
9subpulmonary stenosis10.3AQP1, AQP4
10dystrophinopathies10.3AQP1, AQP4
11early myoclonic encephalopathy10.2MGMT, PCNA
12cerebrospinal fluid leak10.2
13headache10.2
14papillary ependymoma10.1AQP1, NF2
15facial paralysis10.1
1646 xy gonadal dysgenesis10.1AQP1, AQP4, TGFB1
17lens disease10.1AQP1, AQP4
18meningitis10.1
19gallbladder papillary carcinoma10.0NF2, PARP1
20hydrocephalus10.0
21glioma10.0
22sensorineural hearing loss10.0
23glioblastoma10.0
24aneurysm10.0
25dysostosis9.9MSH2, PARP1, TGFB1
26atrophic rhinitis9.9AQP1, AQP4, PARP1
27mastoiditis9.9
28arachnoiditis9.9
29glioblastoma multiforme9.9
30cerebritis9.9
31herpes simplex9.9
32charcot-marie-tooth disease, type 4b19.9NBN, PCNA
33newborn respiratory distress syndrome9.8AQP1, AQP4
34lung cancer9.7
35otitis media9.7
36costello syndrome9.7
37nasopharyngeal carcinoma9.7
38trigeminal neuralgia9.7
39cataract9.7
40gastric cancer9.7
41intracranial abscess9.7
42nasopharyngitis9.7
43intracranial aneurysm9.7
44pulmonary edema9.7
45otosclerosis9.7
46vestibular neuronitis9.7
47communicating hydrocephalus9.7
48neurilemmoma9.7
49laryngitis9.7
50medullomyoblastoma9.7

Graphical network of the top 20 diseases related to Acoustic Neuroma:



Diseases related to acoustic neuroma

Symptoms for Acoustic Neuroma

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UMLS symptoms related to Acoustic Neuroma:


back pain, coughing, headache, pain, sciatica, seizures, snoring, syncope, tremor, chronic pain, sore throat, vertigo/dizziness, equilibration disorder, sleeplessness, bruns nystagmus

Drugs & Therapeutics for Acoustic Neuroma

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Drugs for Acoustic Neuroma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 60)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1GentamicinsPhase 4137
2Anti-Bacterial AgentsPhase 4, Phase 2, Early Phase 110884
3Anti-Infective AgentsPhase 4, Phase 2, Early Phase 121402
4
Methylprednisoloneapproved, vet_approvedPhase 3115383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
5
Prednisoloneapproved, vet_approvedPhase 3115350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
6Neuroprotective AgentsPhase 31672
7Methylprednisolone HemisuccinatePhase 31153
8Peripheral Nervous System AgentsPhase 3, Phase 222776
9Prednisolone hemisuccinatePhase 31153
10Protective AgentsPhase 37190
11Prednisolone phosphatePhase 31153
12Prednisolone acetatePhase 31153
13Methylprednisolone acetatePhase 31153
14Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 312767
15Anti-Inflammatory AgentsPhase 3, Phase 210355
16AntiemeticsPhase 33888
17Autonomic AgentsPhase 39774
18Antineoplastic Agents, HormonalPhase 35407
19Gastrointestinal AgentsPhase 38109
20Hormone AntagonistsPhase 312778
21HormonesPhase 313979
22glucocorticoidsPhase 34920
23
EverolimusapprovedPhase 2, Early Phase 11896159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
Zortress
everolimus
24
Miconazoleapproved, investigational, vet_approvedPhase 2, Early Phase 1362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
25
Sirolimusapproved, investigationalPhase 2, Early Phase 1189653123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
26
Bevacizumabapproved, investigationalPhase 2, Phase 11968216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
27
Axitinibapproved, investigationalPhase 2106319460-85-06450551
Synonyms:
319460-85-0
790713-39-2
AC-1539
AC1O51X3
AG 013736
AG-013736
AG-013736, Axitinib
AG-13736
AG013736
Axitinib
C503983
 
CID6450551
EC-000.2322
I14-1971
INLYTA
Inlyta
MolPort-006-392-413
N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide
N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide
S1005_Selleck
ST51054130
UNII-C9LVQ0YUXG
ZINC03816287
axitinib
28
Lapatinibapproved, investigational, Approved March 2007Phase 2, Early Phase 1296231277-92-2, 388082-78-8208908, 9941095
Synonyms:
1xkk
231277-92-2
388082-78-8
4-[[3-Chloro-4-(3-fluorobenzyloxy)phenyl]amino]-6-[5-[[(2-methanesulfonylethyl)amino]methyl]furan-2-yl]quinazoline
AB1004631
AC-1314
AC1L4LL4
AKOS005145766
CHEBI:49603
CHEMBL1201179
CHEMBL554
CID11557040
CID208908
D04024
D08108
DB01259
DB02584
EN002712
FMM
GSK 572016
GSK572016
GW 572016
GW 572016X
GW-2016
GW-572016
GW-572016F
GW2016
GW572016
HMS2089H10
I01-1247
 
Kinome_3684
Kinome_3685
LAPATINIB DITOSYLATE MONOHYDRATE
LS-187029
LS-187771
Lapatinib
Lapatinib (INN)
Lapatinib Ditosylate
Lapatinib [INN]
Lapatinib ditosylate
Lapatinib ditosylate (USAN)
Lapatinib tosilate hydrate
Lapatinib tosilate hydrate (JAN)
Lapatinib, Tykerb, GW572016
N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-((2-methylsulfonylethylamino)methyl)-2-furyl)quinazolin-4-amine
N-(3-Chloro-4-{[(3-fluorophenyl)methyl]oxy}phenyl)-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furanyl]-4-quinazolinamine
N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE
N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine
NCGC00167507-01
NSC745750
TL80090051
Tycerb
Tykerb
Tykerb (TN)
Tyverb
UNII-0VUA21238F
lapatinib
lapatinib ditosylate
nchembio866-comp20
29Protein Kinase InhibitorsPhase 2, Early Phase 13612
30AntibodiesPhase 26045
31Angiogenesis Modulating AgentsPhase 2, Phase 14072
32Angiogenesis InhibitorsPhase 2, Phase 14143
33
LactitolPhase 2332585-86-43871
Synonyms:
4-O-b-D-Galactopyranosyl-D-glucitol, 9CI
E966
Emportal
 
Floralac
Importal
Oponaf
Portolac
34EndostatinsPhase 26871581480
35Immunosuppressive AgentsPhase 2, Early Phase 112770
36ImmunoglobulinsPhase 26045
37Antibiotics, AntitubercularPhase 2, Early Phase 16972
38Antifungal AgentsPhase 2, Early Phase 13615
39Antibodies, MonoclonalPhase 23795
40Anti-Inflammatory Agents, Non-SteroidalPhase 24295
41Analgesics, Non-NarcoticPhase 26260
42Antirheumatic AgentsPhase 210627
43AnalgesicsPhase 211287
446-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazolePhase 25
45
Temozolomideapproved, investigationalPhase 169385622-93-15394
Synonyms:
3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide
3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide
3,4-dihydro-3-Methyl-4-oxoimidazo(5,1-D)-1,2,3,5-tetrazine-8-carboxamide
3,4-dihydro-3-Methyl-4-oxoimidazo(5,1-D)-as-tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-D)(1,2,3,5)tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetraazine-8-carboxamide
3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
8-Carbamoyl-3-methylimidazo(5,1-D)-1,2,3,5-tetrazin-4(3H)-one
8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one
85622-93-1
AC-758
AC1L1K9B
BIDD:GT0204
BRN 5547136
Bio-0147
C047246
C6H6N6O2
CCRG 81045
CCRG-81045
CCRIS 8996
CHEBI:153686
CHEMBL810
CID5394
CPD000466338
D06067
DB00853
Essex brand of temozolomide
HMS2051O12
HMS2090B08
I06-0149
I14-1943
LS-80558
M B 39831
M & B 39831
M&B 39831
M&B-39831
 
M-39831
MB 39831
MLS000759447
MLS001424028
MLS002701861
Methazolastone
NCGC00167429-01
NCGC00167429-02
NCI60_003316
NSC 362856
NSC-362856
NSC362856
SAM001246636
SMR000466338
STK623541
Sch 52365
Sch-52365
Schering brand of temozolomide
Schering-Plough brand of temozolomide
TL8005593
TMZ
TMZ-Bioshuttle
Temodal
Temodal (TN)
Temodar
Temozolamide
Temozolodida
Temozolodida [Spanish]
Temozolomid
Temozolomida
Temozolomide (JAN/USAN/INN)
Temozolomide [INN:BAN]
Temozolomidum
Temozolomidum [Latin]
Témozolomide
UNII-YF1K15M17Y
ZINC01482184
m & b 39831
temozolomide
46
Dacarbazineapproved, investigationalPhase 16744342-03-45351166
Synonyms:
(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide
(5Z)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide
(Dimethyltriazeno)imidazolecarboxamide
37626-23-6
4(5)-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide
4(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide
4-(3,3-Dimethyl-1-triazeno)imidazole-5-carboxamide
4-(3,3-Dimethyltriazeno)imidazole-5-carboxamide
4-(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide
4-(Dimethyltriazeno)imidazole-5-c arboxamide
4-(Dimethyltriazeno)imidazole-5-carboxamide
4-(or 5)-(3,3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide
4-(or 5)-(3,3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide
4-[(1E)-3,3-Dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide
4-[3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide
4342-03-4
5(or 4)-(dimethyltriazeno)imidazol e-4(or 5)-carboxamide
5(or 4)-(dimethyltriazeno)imidazole-4(or 5)-carboxamide
5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide
5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide
5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide
5-(3,3-Dimethyltri azeno)imidazole-4-carboxamide
5-(3,3-Dimethyltriazeno)-imidazole-4-carbamide
5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide
5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
5-(Dimethyltriazeno)-4-imidazolecarboxamide
5-(Dimethyltriazeno)imidazole-4-carboxamide
5-(Dimethyltriazeno)imidazole-4-carboximide
5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide
5-[3,3-Dimethyl-1-triazenyl]imidazole-4-carboxamide
94361-71-4
AC1NQXVV
AC1NS01W
AC1NS4BN
AI3-52825
BPBio1_000428
BRD-K35520305-001-07-8
BSPBio_000388
BSPBio_002091
Biocarbazin
Biocarbazine
Biocarbazine R
C6H10N6O
CAS-891986
CCRIS 190
CHEBI:4305
CHEMBL476
CID5281007
CID5351166
CID5353562
Carboxamide, Dimethyl Imidazole
D00288
D003606
D2390_SIGMA
D3634
DB00851
DIC
DTCI
DTIC
DTIC Dome
DTIC, DTIC-Dome, Dacarbazine
DTIC-Dome
DTICDome
DTIE
Dacarbazin
Dacarbazina
Dacarbazine
Dacarbazine (JAN/USP/INN)
Dacarbazine [USAN:INN:BAN:JAN]
Dacarbazino
Dacarbazino [INN-Spanish]
Dacarbazinum
Dacarbazinum [INN-Latin]
 
Dacatic
Decarbazine
Deticene
Di-me-triazenoimidazolecarboxamide
Di-methyl-triazenoimidazolecarboxamide
Dimethyl Imidazole Carboxamide
Dimethyl Triazeno Imidazole Carboxamide
Dimethyltriazenoimidazolecarboxamide
DivK1c_000326
Dtic-Dome
Dtic-Dome (TN)
Dtic-dome (tn)
EINECS 224-396-1
HE1150000
HMS1569D10
HMS2090A20
HMS2091I20
HMS501A08
HSDB 3219
I06-2280
I14-1659
ICDMT
ICDT
IDI1_000326
Imidazole Carboxamide
Imidazole Carboxamide, Dimethyl
Imidazole carboxamide
KBio1_000326
KBio2_001364
KBio2_003932
KBio2_006500
KBio3_001311
KBioGR_000896
KBioSS_001364
LS-119
MLS001332543
MLS001332544
MolPort-003-666-153
MolPort-003-846-120
MolPort-006-709-420
NCGC00016986-01
NCGC00091861-01
NCGC00091861-02
NCGC00091861-03
NCGC00091861-04
NCI-C04717
NCI60_004053
NCIMech_000261
NINDS_000326
NIOSH/HE1150000
NPFAPI-05
NSC 45388
NSC-45388
NSC45388
Prestwick0_000574
Prestwick1_000574
Prestwick2_000574
Prestwick3_000574
Prestwick_904
S1221_Selleck
SMP2_000251
SMR000857131
SPBio_001075
SPBio_002607
SPECTRUM1500218
ST51014976
Spectrum2_001148
Spectrum3_000366
Spectrum4_000308
Spectrum5_000823
Spectrum_000884
UNII-7GR28W0FJI
WLN: T5M CNJ DVZ ENUNN1&1
dacarbazine
47Alkylating AgentsPhase 14694
48Antineoplastic Agents, AlkylatingPhase 14474
49
MentholapprovedEarly Phase 123532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
50
Octreotideapproved, investigational21383150-76-9383414, 6400441
Synonyms:
(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
79517-01-4 (acetate salt)
83150-76-9
AC1L1GVU
AC1L8LCD
AC1L9M4X
C07306
C5H12O2.C4H10
CHEBI:427278
CHEBI:611465
CHEMBL1680
CID383414
CID448601
CID54374
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide
D00442
DRG-0115
HMS2090C09
HS-2020
 
L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*
L000453
LS-177735
LS-187135
Longastatin
NCGC00181796-01
NCI60_025753
Octreotida
Octreotida [Spanish]
Octreotide
Octreotide (USAN/INN)
Octreotide Acetate Salt
Octreotide [USAN:INN:BAN]
Octreotide-LAR
Octreotidum
Octreotidum [Latin]
Octrotide
SAN 201-995
SM 201-995
SMS 201-995
SMS-201-995
Sandostatine
Sandoz 201-995
UNII-RWM8CCW8GP
nchembio.184-comp3
zacycloicosane-4-carboxamide acetate

Interventional clinical trials:

(show all 49)
idNameStatusNCT IDPhase
1Gentamicin Treatment Prior to Schwannoma Surgery - Residual FunctionRecruitingNCT02379754Phase 4
2Gentamicin Treatment Prior to Schwannoma Surgery - No Residual FunctionRecruitingNCT02415257Phase 4
3Stereotactic Radiation in Vestibular SchwannomaUnknown statusNCT01449604Phase 3
4Corticosteroids in Prevention of Facial Palsy After Cranial Base SurgeryCompletedNCT00438087Phase 3
5Vestibular Schwannoma - Radiosurgery or Expectation: V-REX.RecruitingNCT02249572Phase 2, Phase 3
6Cyberknife Radiosurgery for Patients With NeurinomasRecruitingNCT02055859Phase 3
7Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2)CompletedNCT01207687Phase 2
8Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related TumorsCompletedNCT02104323Phase 2
9Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related TumorsCompletedNCT00973739Phase 2
10Phase II Study of the Multichannel Auditory Brain Stem Implant for Deafness Following Surgery for Neurofibromatosis 2CompletedNCT00004437Phase 2
11Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2CompletedNCT01419639Phase 2
12Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular SchwannomasRecruitingNCT01767792Phase 2
13Study of RAD001 for Treatment of NF2-related Vestibular SchwannomaRecruitingNCT01345136Phase 2
14Hearing Outcomes Using Fractionated Proton Radiation Therapy for Vestibular SchwannomaRecruitingNCT01199978Phase 2
15Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular SchwannomasRecruitingNCT02129647Phase 2
16Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related TumorsRecruitingNCT02934256Phase 2
17AZD2014 In NF2 Patients With Progressive or Symptomatic MeningiomasRecruitingNCT02831257Phase 2
18Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) PatientsActive, not recruitingNCT01490476Phase 2
19Bevacizumab in Treating Patients With Recurrent or Progressive MeningiomasActive, not recruitingNCT01125046Phase 2
20PTC299 for Treatment of Neurofibromatosis Type 2SuspendedNCT00911248Phase 2
21A Study of Nilotinib in Growing Vestibular SchwannomasTerminatedNCT01201538Phase 2
22RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant GliomaCompletedNCT01119599Phase 1
23An Implant for Hearing Loss Due to Removal of Neurofibromatosis 2 TumorsCompletedNCT00030043Phase 1
24Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Vestibular SchwannomaSuspendedNCT01083966Phase 1
25Vestibular Schwannoma and Psychological FactorsUnknown statusNCT01743248
26Concentration and Activity of Lapatinib in Vestibular SchwannomasUnknown statusNCT00863122Early Phase 1
27Effect of Implant Position on Magnetic Resonance Image DistortionUnknown statusNCT02246231
28Taste Disorders in Middle Ear Disease and After Middle Ear SurgeryUnknown statusNCT01584011
29NF2 Natural History ConsortiumUnknown statusNCT00004483
30Vertigo Perception and Quality of Life in Patients After Surgical Treatment of Vestibular SchwannomaCompletedNCT02963896
31Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II PatientsCompletedNCT01222728
32A Case-Referent Study of Brain Tumors in AdultsCompletedNCT00339300
33A Family Study of Adults With GliomaCompletedNCT00339352
34Recovery of Visual Acuity in People With Vestibular DeficitsCompletedNCT00411216
35Vasopressin and V2 Receptor in Meniere's DiseaseCompletedNCT00599560
36Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With SkypeCompletedNCT02298270
37Gamma Knife Radiosurgery vs Initial Conservative Treatment for Vestibular Schwannoma Patients With Preserved Hearing, a Prospective Randomized StudyRecruitingNCT01938677
38Preoperative Vestibular Rehabilitation Effectiveness After Vestibular Schwannoma SurgeryRecruitingNCT02275325
39Subtotal Resection of Large Acoustic Neuromas With Possible Stereotactic Radiation TherapyRecruitingNCT01129687
40Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and MeningiomaRecruitingNCT02282917Early Phase 1
41Exploring the Activity of RAD001 in Vestibular Schwannomas and MeningiomasRecruitingNCT01880749Early Phase 1
42Cochlear Implantation After Labyrinthectomy or a Translabyrinthine Surgical ApproachRecruitingNCT02309099
43Hearing Handicap in Patients With Single Sided DeafnessRecruitingNCT02525640
44Neurofibromatosis (NF) Registry PortalRecruitingNCT01885767
45Natural History Study of Patients With Neurofibromatosis Type 2Active, not recruitingNCT00598351
46Auditory Nerve Monitoring Using Intra-cochlear Stimulation in Subjects With Acoustic NeuromaNot yet recruitingNCT02948790
47Resiliency Training for Patients With NF2 Via Videoconferencing With SkypeNot yet recruitingNCT02811718
48Compassionate Use Arm - ABI541 ABI for 10 NF2 PatientsNo longer availableNCT02589912
49Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain TumorsSuspendedNCT02194452

Search NIH Clinical Center for Acoustic Neuroma


Cochrane evidence based reviews: neuroma, acoustic

Genetic Tests for Acoustic Neuroma

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Genetic tests related to Acoustic Neuroma:

id Genetic test Affiliating Genes
1 Vestibular Schwannoma26

Anatomical Context for Acoustic Neuroma

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MalaCards organs/tissues related to Acoustic Neuroma:

35
Brain, Testes, Bone, Temporal lobe, Pituitary, Lung, Eye

Animal Models for Acoustic Neuroma or affiliated genes

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MGI Mouse Phenotypes related to Acoustic Neuroma:

40 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.9LIG1, MGMT, MSH2, NBN, NF2, TGFB1
2MP:00053898.6ABCA2, AQP1, NBN, NF2, PARP1, PCNA
3MP:00053798.3AQP1, AQP4, LIG1, MGMT, NBN, NF2
4MP:00036318.1ABCA2, AQP1, AQP4, MSH2, NBN, NF2
5MP:00053877.9AQP4, LIG1, MSH2, NBN, NF2, PARP1
6MP:00053977.9AQP1, AQP4, LIG1, MSH2, NBN, PARP1
7MP:00053787.7ABCA2, AQP1, AQP4, LIG1, NBN, NF2
8MP:00053767.2ABCA2, AQP1, AQP4, LIG1, MGMT, MSH2
9MP:00107686.9ABCA2, AQP1, AQP4, LIG1, MGMT, MSH2

Publications for Acoustic Neuroma

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Articles related to Acoustic Neuroma:

(show top 50)    (show all 570)
idTitleAuthorsYear
1
Tinnitus following treatment for sporadic Acoustic neuroma. (26403598)
2015
2
Acoustic neuroma manifesting as toothache and numbness. (25625716)
2015
3
Preoperative Lumbar Drain Use During Acoustic Neuroma Surgery and Effect on CSF Leak Incidence. (26239000)
2015
4
Facial neuroma masquerading as acoustic neuroma. (24775608)
2014
5
A case of gastric cancer manifesting as a solitary brain metastasis in the cerebellopontine angle that mimicked acoustic neuroma. (24400217)
2013
6
The safe zone of posterior semicircular canal resection in suboccipital retrosigmoid sinus approach for acoustic neuroma surgery. (24220416)
2013
7
Acoustic neuroma observation associated with an increase in symptomatic tinnitus: results of the 2007-2008 Acoustic Neuroma Association survey. (23790115)
2013
8
Recurrent nasopharyngeal carcinoma masquerading as acoustic neuroma. (22434308)
2012
9
Acoustic neuroma neurophysiologic correlates: vestibular-preoperative, intraoperative, and postoperative. (22483818)
2012
10
Hearing preservation surgery in acoustic neuroma: long-term results. (22767970)
2012
11
Retromastoid-sub occipital: A novel approach to cerebello pontine angle in acoustic neuroma surgery-our experience in 21 cases. (21716801)
2011
12
Re: Evaluation of cost effectiveness for conservative and active management strategies for acoustic neuroma. (20447172)
2010
13
Can loud noise cause acoustic neuroma? Analysis of the INTERPHONE study in France. (19289391)
2009
14
Cell phone use and acoustic neuroma: the need for standardized questionnaires and access to industry data. (19328527)
2009
15
Future perspectives in acoustic neuroma management. (18810226)
2008
16
What can be learned from the Japanese study of mobile phone use and acoustic neuroma? (18487430)
2008
17
Stress hormones in MAcniA"re's disease and acoustic neuroma. (15925138)
2005
18
Metastatic lung cancer in the cerebellopontine angles mimicking bilateral acoustic neuroma. (15749427)
2005
19
Mobile phone use and risk of acoustic neuroma: results of the Interphone case-control study in five North European countries. (16136046)
2005
20
Perioperative complications in acoustic neuroma (vestibular schwannoma) surgery. (15129121)
2004
21
Acoustic neuroma radiosurgery. Origins, contemporary use and future expectations. (15179299)
2004
22
Cerebrospinal fluid leak after acoustic neuroma surgery: a comparison of the translabyrinthine, middle fossa, and retrosigmoid approaches. (12544038)
2003
23
The effect of age on acoustic neuroma surgery outcomes. (12806302)
2003
24
Gaze-evoked tinnitus following acoustic neuroma resection: a de-afferentation plasticity phenomenon? (12383293)
2002
25
Acoustic neuroma: predominance of Antoni type B cells in tumors of patients with vestibular paresis. (11300272)
2001
26
Cerebrospinal fluid leak after acoustic neuroma surgery: influence of tumor size and surgical approach on incidence and response to treatment. (11213957)
2001
27
Consensus meeting on systems for reporting results in acoustic neuroma. November 7-9, 2001. Tokyo, Japan. Abstracts. (11758537)
2001
28
Otolith function after acoustic neuroma surgery. (11677734)
2001
29
Intracochlea acoustic neuroma: a case report and discussion. (11829196)
2001
30
Navigation-guided opening of the internal auditory canal via the retrosigmoid route for acoustic neuroma surgery: cadaveric, radiological, and preliminary clinical study. (10942011)
2000
31
Prognostic significance of preoperative electrophysiologic investigation for facial nerve outcome in acoustic neuroma surgery. (11102911)
2000
32
MRI screening for acoustic neuroma. (11271911)
2000
33
Acoustic neuroma: outcome of surgical resection and study on the anatomy of facial and cochlear nerves. (10575527)
1999
34
Stereocilia-like structures in the endolymphatic sac in MAcniA"re's disease and acoustic neuroma. (9892873)
1999
35
There is a role for ABR audiometry in the diagnosis of acoustic neuroma. (10037294)
1999
36
Assessment of dysequilibrium after acoustic neuroma removal. (10431891)
1999
37
Disability from vestibular symptoms after acoustic neuroma resection. (9455958)
1998
38
Stereotactic radiosurgery for acoustic neuroma: a Canadian perspective. (9827233)
1998
39
Is the presence of transient evoked otoacoustic emmissions in ears with acoustic neuroma significant? (9546278)
1998
40
Individualizing hearing preservation in acoustic neuroma surgery. (9261005)
1997
41
Role of transient-evoked otoacoustic emissions for hearing preservation in acoustic neuroma surgery. (9391671)
1997
42
Non-acoustic neuroma tumor (NANT) of the cerebello-pontine angle: a 15-year experience. (9385566)
1997
43
Socioeconomic impact of acoustic neuroma surgery. (9233482)
1997
44
Electromyographic analysis of profound facial nerve paralysis following acoustic neuroma resection. (9186971)
1997
45
Preoperative electroneuronography and facial nerve outcome in acoustic neuroma surgery. (9149839)
1997
46
A technique to reduce CSF leakage after acoustic neuroma surgery. (9474273)
1997
47
Normal hearing in acoustic neuroma patients: a critical evaluation. (8694116)
1996
48
Molecular genetic analysis of the mechanism of tumorigenesis in acoustic neuroma. (8217082)
1993
49
Ramsay Hunt syndrome mimicking intracanalicular acoustic neuroma on contrast-enhanced MR. (2107729)
1990
50
Diagnosis of middle ear disease and acoustic neuroma. (6859244)
1983

Variations for Acoustic Neuroma

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Expression for genes affiliated with Acoustic Neuroma

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Search GEO for disease gene expression data for Acoustic Neuroma.

Pathways for genes affiliated with Acoustic Neuroma

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GO Terms for genes affiliated with Acoustic Neuroma

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Cellular components related to Acoustic Neuroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nuclear chromosome, telomeric regionGO:00007849.1MSH2, NBN, PARP1, PCNA
2nucleusGO:00056346.0AQP1, LIG1, MGMT, MSH2, NBN, NF2

Biological processes related to Acoustic Neuroma according to GeneCards Suite gene sharing:

(show all 30)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of DNA replicationGO:000815610.4NF2, TGFB1
2negative regulation of cell-cell adhesionGO:002240810.4NF2, TGFB1
3glycerol transportGO:001579310.4AQP1, AQP4
4cellular water homeostasisGO:000999210.4AQP1, AQP4
5lens fiber cell differentiationGO:007030610.4NF2, TGFB1
6cell-cell junction organizationGO:004521610.4NF2, TGFB1
7water transportGO:000683310.3AQP1, AQP4
8positive regulation of DNA repairGO:004573910.3MGMT, PCNA
9multicellular organismal water homeostasisGO:005089110.3AQP1, AQP4
10liver regenerationGO:009742110.3PCNA, TGFB1
11cellular response to ionizing radiationGO:007147910.3MGMT, TGFB1
12nucleotide-excision repair, DNA gap fillingGO:000629710.2LIG1, PCNA
13renal water homeostasisGO:000309110.2AQP1, AQP4
14positive regulation of transcription regulatory region DNA bindingGO:200067910.1PARP1, TGFB1
15isotype switchingGO:004519010.1MSH2, NBN
16positive regulation of protein localization to nucleusGO:190018210.0PARP1, TGFB1
17cellular response to dexamethasone stimulusGO:007154910.0AQP1, TGFB1
18positive regulation of SMAD protein import into nucleusGO:006039110.0PARP1, TGFB1
19telomere maintenanceGO:00007239.9NBN, PCNA
20mitotic cell cycle checkpointGO:00070939.9NBN, TGFB1
21DNA ligation involved in DNA repairGO:00511039.9LIG1, PARP1
22telomere maintenance via recombinationGO:00007229.9LIG1, PCNA
23nucleotide-excision repair, DNA incision, 5-to lesionGO:00062969.9PARP1, PCNA
24nucleotide-excision repair, DNA incisionGO:00336839.9PARP1, PCNA
25mismatch repairGO:00062989.8LIG1, MSH2, PCNA
26DNA damage response, detection of DNA damageGO:00427699.7PARP1, PCNA
27cell cycle arrestGO:00070509.5MSH2, NBN, TGFB1
28double-strand break repairGO:00063029.3MSH2, NBN, PARP1
29response to drugGO:00424939.2ABCA2, AQP1, MGMT, TGFB1
30DNA repairGO:00062818.8LIG1, MGMT, MSH2, PARP1

Molecular functions related to Acoustic Neuroma according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1dinucleotide insertion or deletion bindingGO:003213910.3MSH2, PCNA
2glycerol channel activityGO:001525410.3AQP1, AQP4
3water channel activityGO:001525010.3AQP1, AQP4
4water transmembrane transporter activityGO:000537210.3AQP1, AQP4
5MutLalpha complex bindingGO:003240510.2MSH2, PCNA
6DNA ligase (ATP) activityGO:00039109.9LIG1, PARP1
7protein N-terminus bindingGO:00474859.2NBN, PARP1, TGFB1
8damaged DNA bindingGO:00036849.1MGMT, MSH2, NBN, PCNA
9enzyme bindingGO:00198998.8MSH2, PARP1, PCNA, TGFB1

Sources for Acoustic Neuroma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet