MCID: ACQ012
MIFTS: 23

Acquired Angioedema malady

Summaries for Acquired Angioedema

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Acquired Angioedema, also known as angioedema,acquired, is related to angioedema and hereditary angioedema. An important gene associated with Acquired Angioedema is C1S (complement component 1, s subcomponent), and among its related pathways are Pertussis and Immune response Lectin induced complement pathway. The compounds inogatran and hirugen have been mentioned in the context of this disorder.

Aliases & Classifications for Acquired Angioedema

About this section
Sources:
42NIH Rare Diseases, 60UMLS
See all sources

Aliases & Descriptions:

acquired angioedema 42 60
angioedema,acquired 42


Related Diseases for Acquired Angioedema

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Angioedema family:

acquired angioedema Acquired Angioedema Type 1
Acquired Angioedema Type 2

Diseases related to Acquired Angioedema via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 68)
idRelated DiseaseScoreTop Affiliating Genes
1angioedema31.3SERPING1, C1S
2hereditary angioedema30.9C1S, SERPING1
3c1 inhibitor deficiency30.6SERPING1
4antithrombin iii deficiency30.0SERPINC1, F5
5antiphospholipid syndrome30.0SERPINC1, F5
6chronic lymphocytic leukemia10.2
7leukemia10.2
8angioedema induced by ace inhibitors10.2
9acquired angioedema type 110.2
10acquired angioedema type 210.2
11hepatitis c10.0
12psoriatic arthritis10.0
13autoimmune hemolytic anemia10.0
14anaplastic large cell lymphoma10.0
15arthritis10.0
16hemolytic anemia10.0
17hepatitis10.0
18hodgkin's lymphoma10.0
19myelofibrosis10.0
20vasculitis10.0C1S
21branch retinal artery occlusion10.0F5
22retinal vascular occlusion10.0F5
23central retinal vein occlusion10.0F5
24acute pancreatitis10.0C1S
25patent foramen ovale10.0F5
26ovarian hyperstimulation syndrome10.0F5
27sneddon syndrome10.0SERPINC1
28coronary thrombosis10.0SERPINC1
29purpura10.0SERPINC1
30ischemia10.0C1S
31thrombocytosis10.0SERPINC1
32urticaria10.0SERPING1, C1S
33capillary leak syndrome10.0C1S, SERPING1
34respiratory failure10.0SERPINC1
35stroke, ischemic10.0F5
36purpura fulminans10.0SERPINC1, F5
37postphlebitic syndrome10.0F5, SERPINC1
38legg-calve-perthes disease10.0F5, SERPINC1
39prothrombin deficiency10.0SERPINC1, F5
40hepatic vein thrombosis10.0F5, SERPINC1
41sagittal sinus thrombosis10.0F5, SERPINC1
42blood protein disease10.0F5, SERPINC1
43intracranial thrombosis10.0F5, SERPINC1
44dysfibrinogenemia10.0F5, SERPINC1
45meningococcemia10.0F5, SERPINC1
46factor xii deficiency10.0F5, SERPINC1
47hemorrhagic disease10.0F5, SERPINC1
48factor vii deficiency10.0F5, SERPINC1
49factor viii deficiency10.0F5, SERPINC1
50pregnancy loss10.0F5, SERPINC1

Graphical network of the top 20 diseases related to Acquired Angioedema:



Diseases related to acquired angioedema

Clinical Features for Acquired Angioedema

About this section

Drugs & Therapeutics for Acquired Angioedema

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Acquired Angioedema

Drug clinical trials:

Search ClinicalTrials for Acquired Angioedema

Search NIH Clinical Center for Acquired Angioedema

Search CenterWatch for Acquired Angioedema

Genetic Tests for Acquired Angioedema

About this section

Anatomical Context for Acquired Angioedema

About this section

Animal Models for Acquired Angioedema or affiliated genes

About this section

Publications for Acquired Angioedema

About this section

Genetic Variations for Acquired Angioedema

About this section

Expression for genes affiliated with Acquired Angioedema

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Acquired Angioedema

Search GEO for disease gene expression data for Acquired Angioedema.

Pathways for genes affiliated with Acquired Angioedema

About this section
Sources:
29KEGG, 12EMD Millipore, 51QIAGEN, 55SinoBiological, 37NCBI BioSystems Database, 53Reactome, 52R&D Systems
See all sources

Compounds for genes affiliated with Acquired Angioedema

About this section
Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 59Tocris Bioscience, 28IUPHAR, 2BitterDB, 24HMDB
See all sources

Compounds related to Acquired Angioedema according to GeneCards/GeneDecks:

(show all 46)
idCompoundScoreTop Affiliating Genes
1inogatran449.6F5, SERPINC1
2hirugen449.6SERPINC1, F5
3ecarin449.6SERPINC1, F5
4spectrozyme449.6SERPINC1, F5
5danaparoid449.6F5, SERPINC1
6nafamostat mesilate449.5F5, SERPINC1
7eltrombopag49 1110.5F5, SERPINC1
8ancrod449.5F5, SERPINC1
9ximelagatran44 1110.5F5, SERPINC1
10heparinoids449.5SERPINC1, F5
11fondaparinux449.5F5, SERPINC1
12bivalirudin44 1110.5F5, SERPINC1
13desogestrel44 1110.5SERPINC1, F5
14argatroban44 1110.5SERPINC1, F5
15gabexate mesilate449.5SERPINC1, F5
16tranexamic acid44 1110.5C1S, SERPINC1
17protamine sulfate449.5F5, SERPINC1
18gestodene44 1110.5SERPINC1, F5
19benzamidine44 1110.5SERPINC1, F5
20ristocetin449.5SERPINC1, F5
21tibolone449.5SERPINC1, F5
22levonorgestrel44 59 28 1112.5F5, SERPINC1
23abciximab44 1110.4SERPINC1, C1S
24desmopressin44 59 28 1112.4SERPINC1, F5
25coumarin44 2 49 2412.4SERPINC1, F5
26fluorescein44 1110.4F5, SERPINC1
27hirudin449.4SERPINC1, F5
28protamine449.4SERPINC1, F5
29dermatan sulfate449.4F5, SERPINC1
30raloxifene44 28 49 1112.3F5, SERPINC1
31dextran sulfate449.3SERPINC1, F5
32warfarin44 49 11 2412.3SERPINC1, F5
33progestin449.2F5, SERPINC1
34polyethylene glycol449.2SERPINC1, F5
35citrate449.1SERPINC1, F5
36kininogen449.1SERPINC1, F5, C1S
37aprotinin44 1110.0SERPINC1, F5, C1S
38prostacyclin449.0SERPINC1, F5, C1S
39aspirin44 49 28 2412.0C1S, F5, SERPINC1
40danazol44 11 2411.0SERPING1, SERPINC1, C1S
41fibrinogen449.0C1S, F5, SERPINC1
42homocysteine44 249.8SERPINC1, F5
43arginine448.6SERPINC1, F5, C1S
44heparin44 28 11 2411.4C1S, F5, SERPINC1, SERPING1
45alanine448.4F5, SERPINC1, SERPING1
46serine448.3C1S, F5, SERPINC1, SERPING1

GO Terms for genes affiliated with Acquired Angioedema

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Acquired Angioedema according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:0310939.0SERPING1, F5
2extracellular spaceGO:0056158.5SERPING1, SERPINC1, F5
3extracellular regionGO:0055767.9SERPING1, SERPINC1, F5, C1S

Biological processes related to Acquired Angioedema according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood circulationGO:0080159.4SERPING1, F5
2platelet degranulationGO:0025769.3SERPING1, F5
3complement activation, classical pathwayGO:0069589.2C1S, SERPING1
4negative regulation of endopeptidase activityGO:0109518.7SERPING1, SERPINC1
5blood coagulationGO:0075968.5SERPING1, SERPINC1, F5

Molecular functions related to Acquired Angioedema according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1serine-type endopeptidase inhibitor activityGO:0048679.0SERPING1, SERPINC1

Products for genes affiliated with Acquired Angioedema

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Acquired Angioedema

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet