MCID: ACQ027
MIFTS: 27

Acquired Cutis Laxa malady

Categories: Genetic diseases, Skin diseases, Rare diseases, Neuronal diseases, Metabolic diseases, Mental diseases, Bone diseases, Gastrointestinal diseases, Nephrological diseases, Eye diseases, Fetal diseases, Cardiovascular diseases

Aliases & Classifications for Acquired Cutis Laxa

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Sources:
51Orphanet, 65UMLS, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Acquired Cutis Laxa:

Name: Acquired Cutis Laxa 51
Cutis Laxa, Acquired Type 65
 
Cutis Laxa Acquisita 51

Characteristics:

Orphanet epidemiological data:

51
cutis laxa acquisita:
Inheritance: Not applicable; Age of onset: All ages

Classifications:

Orphanet: 51 
Rare skin diseases


External Ids:

Orphanet51 228285
UMLS via Orphanet66 C0406549
UMLS65 C0406549

Summaries for Acquired Cutis Laxa

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MalaCards based summary: Acquired Cutis Laxa, also known as cutis laxa, acquired type, is related to leukemia and adenoma. An important gene associated with Acquired Cutis Laxa is FBLN5 (Fibulin 5), and among its related pathways are Degradation of the extracellular matrix and Elastic fibre formation. Affiliated tissues include bone, eye and skin.

Related Diseases for Acquired Cutis Laxa

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Diseases in the Cutis Laxa family:

Cutis Laxa, Ad Cutis Laxa, Autosomal Recessive, Type Iiia
Cutis Laxa, Autosomal Dominant 3 Cutis Laxa, Autosomal Recessive, Type Ib
Cutis Laxa, Autosomal Recessive, Type Iia Cutis Laxa, Autosomal Recessive, Type Ia
Cutis Laxa, Autosomal Dominant 2 Cutis Laxa, Autosomal Recessive, Type Iib
Cutis Laxa, Autosomal Recessive, Type Iiib Cutis Laxa, Autosomal Recessive, Type Ic
Atp6v0a2-Related Cutis Laxa Efemp2-Related Cutis Laxa
Fbln5-Related Cutis Laxa Ltbp4-Related Cutis Laxa
Cutis Laxa, Autosomal Dominant Cutis Laxa, Autosomal Recessive Type 1
Aldh18a1-Related Cutis Laxa Eln-Related Cutis Laxa
Pycr1-Related Cutis Laxa acquired cutis laxa

Diseases related to Acquired Cutis Laxa via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idRelated DiseaseScoreTop Affiliating Genes
1leukemia10.4
2adenoma10.4
3ulcerative colitis10.3
4schizophrenia10.2
5neuroblastoma10.2
6prostate cancer10.2
7breast cancer10.2
8arthritis10.2
9crohn's disease10.2
10gastric cancer10.2
11glycogen storage disease10.2
12hydrocephalus10.2
13hepatocellular adenoma10.2
14lymphoma10.2
15intracranial aneurysm10.2
16schizophreniform disorder10.2
17cardiac tamponade10.2
18diabetic autonomic neuropathy10.2
19autonomic neuropathy10.2
20transient global amnesia10.2
21obstructive jaundice10.2
22prostatitis10.2
23normal pressure hydrocephalus10.2
24keratosis10.2
25vaginitis10.2
26takayasu's arteritis10.2
27basal cell carcinoma10.2
28cystadenoma10.2
29complex regional pain syndrome10.2
30apocrine adenoma10.2
31pancreatic cystadenoma10.2
32pancreatitis10.2
33dystonia10.2
34oral submucous fibrosis10.2
35peritonitis10.2
36subcorneal pustular dermatosis10.2
37neuropathy10.2
38pityriasis rosea10.2
39psoriasis10.2
40croup10.2
41growth hormone deficiency10.2
42nephrogenic systemic fibrosis10.2
43aneurysm10.2
44syncope10.2
45endotheliitis10.2
46myopericytoma10.2
47esophagitis, eosinophilic, 19.8ELN, FBLN5
48linear focal dermal elastosis9.8ELN, FBLN5
49fgfr-related craniosynostosis syndromes9.8ELN, FBLN5
50cutis laxa, autosomal recessive type 19.8ELN, FBLN5

Graphical network of the top 20 diseases related to Acquired Cutis Laxa:



Diseases related to acquired cutis laxa

Symptoms for Acquired Cutis Laxa

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Drugs & Therapeutics for Acquired Cutis Laxa

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Acquired Cutis Laxa

Genetic Tests for Acquired Cutis Laxa

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Anatomical Context for Acquired Cutis Laxa

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MalaCards organs/tissues related to Acquired Cutis Laxa:

33
Bone, Eye, Skin, B cells, Liver, Endothelial

Animal Models for Acquired Cutis Laxa or affiliated genes

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Publications for Acquired Cutis Laxa

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Articles related to Acquired Cutis Laxa:

(show top 50)    (show all 51)
idTitleAuthorsYear
1
Peroral endoscopic myotomy using the posterior approach in an 11-month-old girl with achalasia, severe malnutrition, and recurrent pneumonia. (26479295)
2015
2
Posterior subtenon triamcinolone acetonide injection as a primary treatment in eyes with acute Vogt-Koyanagi-Harada disease. (25792626)
2015
3
Open Conservative Surgical Management of Cystic Echinococcosis in a Tertiary Care Hospital, Nepal. (26393161)
2015
4
Eyelid Finger Manipulation in the Treatment of Overcorrected Blepharoptosis and Postblepharoplasty Ectropion-Retraction. (26186347)
2015
5
Reveromycin A Administration Prevents Alveolar Bone Loss in Osteoprotegerin Knockout Mice with Periodontal Disease. (26561427)
2015
6
Proprioceptive acuity into knee hypermobile range in children with joint hypermobility syndrome. (25278815)
2014
7
A Combination of IFN-I^ and IL-2 Production by Coxiella burnetii Stimulated Circulating Cells Discriminates Between Chronic Q Fever and Past Q Fever. (24118683)
2013
8
Vascular leiomyoma and geniculate ganglion. (23943721)
2013
9
Impact of clinically relevant mutations on the pharmacoregulation and signaling bias of the calcium-sensing receptor by positive and negative allosteric modulators. (23372019)
2013
10
Characterization of Shigella sonnei in Malaysia, an increasingly prevalent etiologic agent of local shigellosis cases. (22606962)
2012
11
Elovl6 promotes nonalcoholic steatohepatitis. (22753171)
2012
12
Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration. (22511793)
2012
13
Leads from xenobiotic metabolism genes for Parkinson's disease among north Indians. (22016051)
2011
14
Multinational cholera outbreak after wedding in the Dominican Republic. (22204039)
2011
15
The RNA-binding protein Sam68 is a multifunctional player in human cancer. (21565971)
2011
16
Optimization of the degenerated interfacial ATP binding site improves the function of disease-related mutant cystic fibrosis transmembrane conductance regulator (CFTR) channels. (20861014)
2010
17
The double edge of reactive oxygen species as damaging and signaling molecules in HL60 cell culture. (20110685)
2010
18
Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells. (19506300)
2009
19
Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6. (18445007)
2008
20
Chemical synthesis and 1H-NMR 3D structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxins. (18042681)
2008
21
Expression of Fas, Fas ligand, Fas-associated death domain protein, caspase 8 and mutant P53 protein in esophageal squamous cell carcinoma]. (17425843)
2007
22
Differential interactions between Beclin 1 and Bcl-2 family members. (17643073)
2007
23
Optimized protocol to reduce variable outcomes for the bilateral common carotid artery occlusion model in mice. (17692388)
2007
24
Synthesis and biological evaluation of 9-(5',5'-difluoro-5'-phosphonopentyl)guanine derivatives for PNP-inhibitors. (16263289)
2006
25
Polymorphonuclear leucocytes selectively produce anti-inflammatory interleukin-1 receptor antagonist and chemokines, but fail to produce pro-inflammatory mediators. (17067311)
2006
26
Impact of the operator's experience on value of high-resolution transabdominal ultrasound in the diagnosis of choledocholithiasis: a prospective comparison using endoscopic retrograde cholangiography as the gold standard. (16785198)
2006
27
4'-phosphopantetheine biosynthesis in Archaea. (16371361)
2006
28
Germ cell nuclear factor is a repressor of CRIPTO-1 and CRIPTO-3. (16954206)
2006
29
Can cystatin C be a better marker for the early detection of renal damage in primary hypertensive patients? (15957539)
2005
30
Nervous system involvement in Degos disease. (15760880)
2005
31
Transcriptional regulation of the human CD3 gamma gene: the TATA-less CD3 gamma promoter functions via an initiator and contiguous Sp-binding elements. (15879122)
2005
32
Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis. (14730346)
2004
33
Renal replacement lipomatosis: MR findings in one case. (15010121)
2004
34
Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog. (12483204)
2003
35
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex. (12556501)
2003
36
Alagille syndrome. (12420920)
2002
37
Molecular analysis of multidrug resistance in feline lymphoma cells. (10976746)
2000
38
Strategies for mutational analysis of the large multiexon ATM gene using high-density oligonucleotide arrays. (9872980)
1998
39
Tachykinin-induced activation of non-specific cation conductance via NK3 neurokinin receptors in guinea-pig intracardiac neurones. (9350618)
1997
40
Retinoic acid receptors beta and gamma distinguish retinoid signals for growth inhibition and neuritogenesis in human neuroblastoma cells. (8954130)
1996
41
Changes in the segmental pattern of sensory neuron projections in the chick hindlimb under conditions of altered cell adhesion molecule function. (8626036)
1996
42
Human cytosolic phospholipase A2 expressed in insect cells is extensively phosphorylated on Ser-505. (7766652)
1995
43
Sympathetic dysfunction mediating cardiovascular regulation in alcoholic neuropathy. (7926889)
1994
44
Xenogeneic ex vivo hemoperfusion of rhesus monkey livers with human blood. (11271329)
1994
45
Leuprolide acetate treatment of catamenial pneumothorax. (8293833)
1994
46
Myxosarcoma in a Sinaloan milksnake. (1813474)
1991
47
Cloning of complementary DNA encoding a functional human interleukin- 8 receptor. (1891716)
1991
48
Effects of gonadotropins, insulin and insulin-like growth factor I on ovarian oxytocin and progesterone production. (1663878)
1991
49
Two siblings of hyperphenylalaninemia: suggestion to a genetic variant of phenylketonuria. (5442719)
1970
50

Variations for Acquired Cutis Laxa

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Expression for genes affiliated with Acquired Cutis Laxa

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Search GEO for disease gene expression data for Acquired Cutis Laxa.

Pathways for genes affiliated with Acquired Cutis Laxa

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Pathways related to Acquired Cutis Laxa according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.1ELN, FBLN5
2
Show member pathways
9.1ELN, FBLN5

GO Terms for genes affiliated with Acquired Cutis Laxa

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Sources for Acquired Cutis Laxa

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet