MCID: ACQ007
MIFTS: 46

Acquired Immunodeficiency Syndrome malady

Immune diseases category

Summaries for Acquired Immunodeficiency Syndrome

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Disease Ontology:9 A human immunodeficiency virus infectious disease that results in reduction in the numbers of cd4-bearing helper t cells below 200 per µl of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has material basis in human immunodeficiency virus 1 or has material basis in human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. opportunistic infections are common in people with aids.

MalaCards based summary: Acquired Immunodeficiency Syndrome, also known as aids, is related to chronic lymphocytic leukemia and hiv-1. An important gene associated with Acquired Immunodeficiency Syndrome is TARDBP (TAR DNA binding protein), and among its related pathways is Hematopoietic cell lineage. The drugs zalcitabine and didanosine and the compound calcium have been mentioned in the context of this disorder. Affiliated tissues include t cells, breast and brain, and related mouse phenotypes are immune system and hematopoietic system.

Aliases & Classifications for Acquired Immunodeficiency Syndrome

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Acquired Immunodeficiency Syndrome, Aliases & Descriptions:

Name: Acquired Immunodeficiency Syndrome 9 11 3 60
Aids 9 37
 
Acquired Immune Deficiency 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Immune diseases


External Ids:

Disease Ontology9 DOID:635
MeSH33 D000163
NCIt38 C2851

Related Diseases for Acquired Immunodeficiency Syndrome

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Graphical network of the top 20 diseases related to Acquired Immunodeficiency Syndrome:



Diseases related to acquired immunodeficiency syndrome

Symptoms for Acquired Immunodeficiency Syndrome

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Drugs & Therapeutics for Acquired Immunodeficiency Syndrome

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Genetic Tests for Acquired Immunodeficiency Syndrome

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Anatomical Context for Acquired Immunodeficiency Syndrome

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MalaCards organs/tissues related to Acquired Immunodeficiency Syndrome:

31
T cells, Breast, Brain, Bone, B cells, Thyroid, Bone marrow, Skin, Colon, Lung, Testes, Monocytes, Endothelial, Lymph node, Spinal cord, Heart, Smooth muscle, Eye, Spleen, Small intestine, Liver, Salivary gland, Adrenal gland, Myeloid, Hypothalamus, Pituitary, Neutrophil

Animal Models for Acquired Immunodeficiency Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Acquired Immunodeficiency Syndrome:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.9MS4A1, CARTPT, TARDBP, CD79B, CD9, TNFRSF17
2MP:00053977.6CD9, CD79B, TARDBP, CARTPT, MS4A1, TNFRSF17

Publications for Acquired Immunodeficiency Syndrome

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Articles related to Acquired Immunodeficiency Syndrome:

(show top 50)    (show all 905)
idTitleAuthorsYear
1
The acquired immunodeficiency syndrome in the State of Rio de Janeiro, Brazil: a spatio-temporal analysis of cases reported in the period 2001-2010. (24893020)
2014
2
Central nervous system infection due to Mycobacterium haemophilum in a patient with acquired immunodeficiency syndrome. (24841195)
2014
3
Duodenal Mycobacterium genavense infection in a patient with acquired immunodeficiency syndrome. (23468152)
2013
4
Acrophialophora fusispora brain abscess in a patient with acquired immunodeficiency syndrome: a case report and review of the literature. (23601455)
2013
5
Treatment of acquired immunodeficiency syndrome with Chinese medicine in China: opportunity, advancement and challenges. (23893134)
2013
6
Molecular characterization of Cystoisospora belli and unizoite tissue cyst in patients with Acquired Immunodeficiency Syndrome. (20825690)
2011
7
Clinical manifestations of treatment-naive patients with acquired immunodeficiency syndrome and responses to highly active antiretroviral therapy in the Taipei Veterans General Hospital: a 5-year prospective study. (21524614)
2011
8
Immune reconstitution--the footing of Chinese medicine treatment for acquired immunodeficiency syndrome. (21611894)
2011
9
Organizing pneumonia in a patient with newly diagnosed acquired immunodeficiency syndrome. (21048369)
2010
10
Association between abnormal contrast sensitivity and mortality among people with acquired immunodeficiency syndrome. (20399927)
2010
11
Paediatric intussusception caused by acquired immunodeficiency syndrome-associated Kaposi sarcoma. (20535484)
2010
12
Case report: Esophageal histoplasmosis associated with disseminated tuberculosis in acquired immunodeficiency syndrome. (19270280)
2009
13
Screening and monitoring antiretrovirals and antivirals in the serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography. (19223034)
2009
14
Prevalence of malnutrition in human immunodeficiency virus/acquired immunodeficiency syndrome orphans in the Nyanza province of Kenya: a comparison of conventional indexes with a composite index of anthropometric failure. (18502236)
2008
15
Case of moyamoya disease in a patient with advanced acquired immunodeficiency syndrome. (18035245)
2007
16
Burkitt's lymphoma: conversion from lymphoma negative to lymphoma positive status over 2 months in a patient with acquired immunodeficiency syndrome (AIDS). (18091062)
2007
17
Rhodococcus equi infection in acquired immunodeficiency syndrome. Computed tomography aspects. (17268743)
2006
18
Sensory neuropathy in human immunodeficiency virus/acquired immunodeficiency syndrome patients: protease inhibitor-mediated neurotoxicity. (16634006)
2006
19
Evaluation of stroma in human immunodeficiency virus/acquired immunodeficiency syndrome-affected bone marrows and correlation with CD4 counts. (16119986)
2005
20
Cardiac tumor as an initial manifestation of acquired immunodeficiency syndrome. (15671621)
2005
21
Acquired immunodeficiency syndrome and the risk of stroke. (14684782)
2004
22
Cardiac tamponade in acquired immunodeficiency syndrome. (12714215)
2003
23
The prevalence of pain in pediatric human immunodeficiency virus/acquired immunodeficiency syndrome as reported by participants in the Pediatric Late Outcomes Study (PACTG 219). (12042556)
2002
24
Association of cytomegalovirus (CMV)-specific CD4+ T lymphocyte reactivity and protective immunity against acquired immunodeficiency syndrome-related CMV retinitis. (12447752)
2002
25
Nonmyeloablative conditioning followed by transplantation of genetically modified HLA-matched peripheral blood progenitor cells for hematologic malignancies in patients with acquired immunodeficiency syndrome. (11781257)
2002
26
Glioblastoma multiforme of the brain stem in a patient with acquired immunodeficiency syndrome. (12376778)
2002
27
Thrombotic microangiopathy in patients with acquired immunodeficiency syndrome before and during the era of introduction of highly active antiretroviral therapy. (12471574)
2002
28
Comparison of bone marrow studies with blood culture for etiological diagnosis of disseminated mycobacterial and fungal infection in patients with acquired immunodeficiency syndrome. (12099341)
2002
29
Association of total dose intensity of chemotherapy in primary central nervous system lymphoma (human non-acquired immunodeficiency syndrome) and survival. (11334269)
2001
30
Mycobacterium simiae infection in a patient with acquired immunodeficiency syndrome. (12010600)
2001
31
Thermophilic multidrug-resistant Campylobacter fetus infection with hypersplenism and histiocytic phagocytosis in a patient with acquired immunodeficiency syndrome. (11170921)
2001
32
Immunomodulatory effect of gold sodium thiomalate on murine acquired immunodeficiency syndrome. (11529562)
2001
33
Association between apolipoprotein E genotypes and cancer risk in patients with acquired immunodeficiency syndrome. (11129992)
2000
34
Molluscum contagiosum eyelid lesions as the initial manifestation of acquired immunodeficiency syndrome. (9262550)
1997
35
Spectrum of Adrenal Dysfunction in Patients with Acquired Immunodeficiency Syndrome Evaluation of Adrenal and Pituitary Reserve with ACTH and Corticotropin-Releasing Hormone Testing. (18406803)
1997
36
New therapies for cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. (9109331)
1997
37
Increased NADPH-diaphorase reactivity and cytokine expression in dorsal root ganglia in acquired immunodeficiency syndrome. (8815158)
1996
38
The assessment and nutritional support of patients with the acquired immunodeficiency syndrome]. (7711150)
1995
39
The detection of acquired immunodeficiency syndrome-associated Kaposi sarcoma cells in pleural effusion by CD34 immunostain. (7690682)
1993
40
Acanthamoeba infection presenting as skin lesions in patients with the acquired immunodeficiency syndrome. (8215828)
1993
41
Acquired immunodeficiency syndrome-associated T-cell lymphoma: evidence for human immunodeficiency virus type 1-associated T-cell transformation. (1373087)
1992
42
Orally administered 566C80 for treatment of ocular toxoplasmosis in a patient with the acquired immunodeficiency syndrome. (1543229)
1992
43
Congenital acquired immunodeficiency syndrome presenting as cor pulmonale in a 10-year-old girl. (2000766)
1991
44
Safety and tolerance of dideoxycytidine as a single agent. Results of early-phase studies in patients with acquired immunodeficiency syndrome (AIDS) or advanced AIDS-related complex. Study Group of the AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases. (2159703)
1990
45
Porphyria cutanea tarda and acquired immunodeficiency syndrome: case reports and literature review. (2256699)
1990
46
Internuclear ophthalmoplegia in acquired immunodeficiency syndrome. (2802452)
1989
47
Mycobacterium marinum infection in a patient with cryptosporidiosis and the acquired immunodeficiency syndrome. (3203532)
1988
48
Eosinophilic pustular folliculitis in the acquired immunodeficiency syndrome. Treatment with ultraviolet B phototherapy. (3362166)
1988
49
Ocular toxoplasmosis in patients with the acquired immunodeficiency syndrome. (3195645)
1988
50
Enteric coccidiosis among patients with the acquired immunodeficiency syndrome. (6334448)
1984

Variations for Acquired Immunodeficiency Syndrome

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Expression for genes affiliated with Acquired Immunodeficiency Syndrome

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Search GEO for disease gene expression data for Acquired Immunodeficiency Syndrome.

Pathways for genes affiliated with Acquired Immunodeficiency Syndrome

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Pathways related to Acquired Immunodeficiency Syndrome according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3CD9, MS4A1

Compounds for genes affiliated with Acquired Immunodeficiency Syndrome

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Sources:
43Novoseek, 49PharmGKB, 24HMDB, 12DrugBank
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Compounds related to Acquired Immunodeficiency Syndrome according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1calcium43 49 24 1211.2CD9, CD79B, CCL3L1, MS4A1, TNFRSF17

GO Terms for genes affiliated with Acquired Immunodeficiency Syndrome

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Cellular components related to Acquired Immunodeficiency Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.0CD9, CD79B, MS4A1

Products for genes affiliated with Acquired Immunodeficiency Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Acquired Immunodeficiency Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet