AIDS
MCID: ACQ007
MIFTS: 61

Acquired Immunodeficiency Syndrome (AIDS) malady

Infectious diseases, Immune diseases categories
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Summaries for Acquired Immunodeficiency Syndrome

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Sources:
8Disease Ontology, 4CDC, 65Wikipedia, 47OMIM, 33MalaCards
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Disease Ontology:8 A human immunodeficiency virus infectious disease that results in reduction in the numbers of cd4-bearing helper t cells below 200 per µl of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has material basis in human immunodeficiency virus 1 or has material basis in human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. opportunistic infections are common in people with aids.

MalaCards: Acquired Immunodeficiency Syndrome, also known as AIDS, is related to tuberculosis and dementia. An important gene associated with Acquired Immunodeficiency Syndrome is CXCL12 (chemokine (C-X-C motif) ligand 12), and among its related pathways is Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions. The drugs zalcitabine and didanosine and the compounds rituximab and mdms have been mentioned in the context of this disorder. Affiliated tissues include t cells, breast and brain, and related mouse phenotypes are immune system and hematopoietic system.

CDC:4 What's New in HIV e-HAP keeps you informed about the latest releases from CDC on HIV and related topics.

Wikipedia:65 Human immunodeficiency virus infection / acquired immunodeficiency syndrome (HIV/AIDS) is a disease of... more...

Description from OMIM:47 609423

Aliases & Classifications for Acquired Immunodeficiency Syndrome

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8Disease Ontology, 47OMIM, 10DISEASES, 45Novoseek, 39NCBI Bookshelf, 62UMLS, 40NCIt, 58SNOMED-CT, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Immune diseases


Aliases & Descriptions:

acquired immunodeficiency syndrome 8 10 62
aids 8 47 45 39
acquired immune deficiency 8


External Ids:

Disease Ontology8 DOID:635
NCIt40 C2851
OMIM47 609423
MeSH35 D000163

Related Diseases for Acquired Immunodeficiency Syndrome

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Acquired Immunodeficiency Syndrome:



Diseases related to acquired immunodeficiency syndrome

Symptoms for Acquired Immunodeficiency Syndrome

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47OMIM
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Clinical features from OMIM:

609423

Drugs & Therapeutics for Acquired Immunodeficiency Syndrome

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42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Genetic Tests for Acquired Immunodeficiency Syndrome

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Anatomical Context for Acquired Immunodeficiency Syndrome

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33MalaCards
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MalaCards organs/tissues related to Acquired Immunodeficiency Syndrome:

33
T cells, Breast, Brain, B cells, Bone, Thyroid, Bone marrow, Monocytes, Endothelial, Colon, Skin, Testes, Lung, Heart, Lymph node, Smooth muscle, Pituitary, Adrenal gland, Salivary gland, Small intestine, Liver, Spinal cord, Spleen, Myeloid, Eye, Hypothalamus

Animal Models for Acquired Immunodeficiency Syndrome or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Acquired Immunodeficiency Syndrome:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.3MS4A1, CARTPT, TARDBP, CD79B, CD9, CXCL12
2MP:00053978.0CD9, CD79B, TARDBP, CARTPT, MS4A1, CXCL12

Publications for Acquired Immunodeficiency Syndrome

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52PubMed
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Articles related to Acquired Immunodeficiency Syndrome:

(show top 50)    (show all 876)
idTitleAuthorsYear
1
Duodenal Mycobacterium genavense infection in a patient with acquired immunodeficiency syndrome. (23468152)
2013
2
Acrophialophora fusispora brain abscess in a patient with acquired immunodeficiency syndrome: a case report and review of the literature. (23601455)
2013
3
Molecular characterization of Cystoisospora belli and unizoite tissue cyst in patients with Acquired Immunodeficiency Syndrome. (20825690)
2011
4
Clinical manifestations of treatment-naive patients with acquired immunodeficiency syndrome and responses to highly active antiretroviral therapy in the Taipei Veterans General Hospital: a 5-year prospective study. (21524614)
2011
5
Immune reconstitution--the footing of Chinese medicine treatment for acquired immunodeficiency syndrome. (21611894)
2011
6
Organizing pneumonia in a patient with newly diagnosed acquired immunodeficiency syndrome. (21048369)
2010
7
Association between abnormal contrast sensitivity and mortality among people with acquired immunodeficiency syndrome. (20399927)
2010
8
Paediatric intussusception caused by acquired immunodeficiency syndrome-associated Kaposi sarcoma. (20535484)
2010
9
Case report: Esophageal histoplasmosis associated with disseminated tuberculosis in acquired immunodeficiency syndrome. (19270280)
2009
10
Screening and monitoring antiretrovirals and antivirals in the serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography. (19223034)
2009
11
Prevalence of malnutrition in human immunodeficiency virus/acquired immunodeficiency syndrome orphans in the Nyanza province of Kenya: a comparison of conventional indexes with a composite index of anthropometric failure. (18502236)
2008
12
Case of moyamoya disease in a patient with advanced acquired immunodeficiency syndrome. (18035245)
2007
13
Burkitt's lymphoma: conversion from lymphoma negative to lymphoma positive status over 2 months in a patient with acquired immunodeficiency syndrome (AIDS). (18091062)
2007
14
An unusual cause of central retinal artery occlusion: acquired immunodeficiency syndrome. (17671949)
2007
15
Rhodococcus equi infection in acquired immunodeficiency syndrome. Computed tomography aspects. (17268743)
2006
16
Sensory neuropathy in human immunodeficiency virus/acquired immunodeficiency syndrome patients: protease inhibitor-mediated neurotoxicity. (16634006)
2006
17
Evaluation of stroma in human immunodeficiency virus/acquired immunodeficiency syndrome-affected bone marrows and correlation with CD4 counts. (16119986)
2005
18
Cardiac tumor as an initial manifestation of acquired immunodeficiency syndrome. (15671621)
2005
19
Acquired immunodeficiency syndrome and the risk of stroke. (14684782)
2004
20
Cardiac tamponade in acquired immunodeficiency syndrome. (12714215)
2003
21
Adherence to heroin dependence therapies and human immunodeficiency virus/acquired immunodeficiency syndrome infection rates among drug abusers. (14648465)
2003
22
The prevalence of pain in pediatric human immunodeficiency virus/acquired immunodeficiency syndrome as reported by participants in the Pediatric Late Outcomes Study (PACTG 219). (12042556)
2002
23
Association of cytomegalovirus (CMV)-specific CD4+ T lymphocyte reactivity and protective immunity against acquired immunodeficiency syndrome-related CMV retinitis. (12447752)
2002
24
Nonmyeloablative conditioning followed by transplantation of genetically modified HLA-matched peripheral blood progenitor cells for hematologic malignancies in patients with acquired immunodeficiency syndrome. (11781257)
2002
25
Glioblastoma multiforme of the brain stem in a patient with acquired immunodeficiency syndrome. (12376778)
2002
26
Thrombotic microangiopathy in patients with acquired immunodeficiency syndrome before and during the era of introduction of highly active antiretroviral therapy. (12471574)
2002
27
Comparison of bone marrow studies with blood culture for etiological diagnosis of disseminated mycobacterial and fungal infection in patients with acquired immunodeficiency syndrome. (12099341)
2002
28
Association of total dose intensity of chemotherapy in primary central nervous system lymphoma (human non-acquired immunodeficiency syndrome) and survival. (11334269)
2001
29
Mycobacterium simiae infection in a patient with acquired immunodeficiency syndrome. (12010600)
2001
30
Thermophilic multidrug-resistant Campylobacter fetus infection with hypersplenism and histiocytic phagocytosis in a patient with acquired immunodeficiency syndrome. (11170921)
2001
31
Immunomodulatory effect of gold sodium thiomalate on murine acquired immunodeficiency syndrome. (11529562)
2001
32
Association between apolipoprotein E genotypes and cancer risk in patients with acquired immunodeficiency syndrome. (11129992)
2000
33
Molluscum contagiosum eyelid lesions as the initial manifestation of acquired immunodeficiency syndrome. (9262550)
1997
34
Spectrum of Adrenal Dysfunction in Patients with Acquired Immunodeficiency Syndrome Evaluation of Adrenal and Pituitary Reserve with ACTH and Corticotropin-Releasing Hormone Testing. (18406803)
1997
35
New therapies for cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. (9109331)
1997
36
Increased NADPH-diaphorase reactivity and cytokine expression in dorsal root ganglia in acquired immunodeficiency syndrome. (8815158)
1996
37
The assessment and nutritional support of patients with the acquired immunodeficiency syndrome]. (7711150)
1995
38
The detection of acquired immunodeficiency syndrome-associated Kaposi sarcoma cells in pleural effusion by CD34 immunostain. (7690682)
1993
39
Acanthamoeba infection presenting as skin lesions in patients with the acquired immunodeficiency syndrome. (8215828)
1993
40
Diffuse microgliosis associated with cerebral atrophy in the acquired immunodeficiency syndrome. (8517682)
1993
41
Acquired immunodeficiency syndrome-associated T-cell lymphoma: evidence for human immunodeficiency virus type 1-associated T-cell transformation. (1373087)
1992
42
Orally administered 566C80 for treatment of ocular toxoplasmosis in a patient with the acquired immunodeficiency syndrome. (1543229)
1992
43
Congenital acquired immunodeficiency syndrome presenting as cor pulmonale in a 10-year-old girl. (2000766)
1991
44
Safety and tolerance of dideoxycytidine as a single agent. Results of early-phase studies in patients with acquired immunodeficiency syndrome (AIDS) or advanced AIDS-related complex. Study Group of the AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases. (2159703)
1990
45
Porphyria cutanea tarda and acquired immunodeficiency syndrome: case reports and literature review. (2256699)
1990
46
Internuclear ophthalmoplegia in acquired immunodeficiency syndrome. (2802452)
1989
47
Mycobacterium marinum infection in a patient with cryptosporidiosis and the acquired immunodeficiency syndrome. (3203532)
1988
48
Eosinophilic pustular folliculitis in the acquired immunodeficiency syndrome. Treatment with ultraviolet B phototherapy. (3362166)
1988
49
Ocular toxoplasmosis in patients with the acquired immunodeficiency syndrome. (3195645)
1988
50
Enteric coccidiosis among patients with the acquired immunodeficiency syndrome. (6334448)
1984

Variations for Acquired Immunodeficiency Syndrome

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Expression for genes affiliated with Acquired Immunodeficiency Syndrome

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Acquired Immunodeficiency Syndrome

Search GEO for disease gene expression data for Acquired Immunodeficiency Syndrome.

Pathways for genes affiliated with Acquired Immunodeficiency Syndrome

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50PathCards, 54R&D Systems, 55Reactome
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Pathways related to Acquired Immunodeficiency Syndrome according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.9CCL3L1, CXCL12

Compounds for genes affiliated with Acquired Immunodeficiency Syndrome

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45Novoseek, 51PharmGKB, 11DrugBank, 29IUPHAR
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Compounds related to Acquired Immunodeficiency Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1rituximab45 51 1111.9MS4A1, CXCL12
2mdms459.8CD9, CXCL12
3ccl345 2910.8CCL3L1, CXCL12
4ccl445 2910.6CCL3L1, CXCL12
5rantes459.5CD9, CCL3L1, CXCL12
6ribonucleic acid459.4CD9, CXCL12, SERPINA7
7phosphoinositide459.4CXCL12, CD79B, CD9

GO Terms for genes affiliated with Acquired Immunodeficiency Syndrome

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16Gene Ontology
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Cellular components related to Acquired Immunodeficiency Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056159.1CARTPT, MS4A1, CXCL12, SERPINA7
2external side of plasma membraneGO:0098978.7CD9, CD79B, MS4A1, CXCL12

Biological processes related to Acquired Immunodeficiency Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to peptide hormoneGO:0434349.8CXCL12, SERPINA7

Products for genes affiliated with Acquired Immunodeficiency Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Acquired Immunodeficiency Syndrome

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet