MCID: ACQ016
MIFTS: 13

Acquired Pure Red Cell Aplasia malady

Immune, Blood categories

Summaries for Acquired Pure Red Cell Aplasia

Sources:
43NIH Rare Diseases, 33MalaCards
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NIH Rare Diseases:43 Acquired pure red cell aplasia (prca) is a bone marrow disorder characterized by a reduction of red blood cells (erythrocytes) produced by the bone marrow. signs and symptoms may include fatigue, lethargy, and/or abnormal paleness of the skin (pallor) due to the anemia the caused by the disorder. in most cases, the cause of acquired prca is unknown (idiopathic). in other cases it may occur secondary to autoimmune disorders, tumors of the thymus gland (thymomas), hematologic cancers, solid tumors, viral infections, or certain drugs. treatment depends on the cause of the condition (if known) but often includes transfusions for individuals who are severely anemic and have cardiorespiratory failure. last updated: 12/14/2011

MalaCards: Acquired Pure Red Cell Aplasia, also known as adult pure red cell aplasia, is related to transient erythroblastopenia of childhood and acquired thrombocytopenia. An important gene associated with Acquired Pure Red Cell Aplasia is EPO (erythropoietin). Affiliated tissues include bone marrow, thymus and skin.

Aliases & Classifications for Acquired Pure Red Cell Aplasia

Sources:
43NIH Rare Diseases, 49Orphanet, 26ICD10 via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Immune, Blood


Aliases & Descriptions:

acquired pure red cell aplasia 43
adult pure red cell aplasia 43 49
idiopathic pure red cell aplasia 43
acquired prca 43


External Ids:

ICD10 via Orphanet26 D60.0
ICD1025 D60

Related Diseases for Acquired Pure Red Cell Aplasia

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17GeneCards, 18GeneDecks
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Diseases related to Acquired Pure Red Cell Aplasia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1transient erythroblastopenia of childhood10.5
2acquired thrombocytopenia10.3
3thymoma10.3
4thrombocytopenia, acquired amegakaryocytic10.3

Clinical Features for Acquired Pure Red Cell Aplasia

Drugs & Therapeutics for Acquired Pure Red Cell Aplasia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Genetic Tests for Acquired Pure Red Cell Aplasia

Anatomical Context for Acquired Pure Red Cell Aplasia

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33MalaCards
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MalaCards organs/tissues related to Acquired Pure Red Cell Aplasia:

33
Bone marrow, Thymus, Skin

Animal Models for Acquired Pure Red Cell Aplasia or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Acquired Pure Red Cell Aplasia

Genetic Variations for Acquired Pure Red Cell Aplasia

Expression for genes affiliated with Acquired Pure Red Cell Aplasia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Acquired Pure Red Cell Aplasia

Search GEO for disease gene expression data for Acquired Pure Red Cell Aplasia.

Pathways for genes affiliated with Acquired Pure Red Cell Aplasia

Compounds for genes affiliated with Acquired Pure Red Cell Aplasia

GO Terms for genes affiliated with Acquired Pure Red Cell Aplasia

Products for genes affiliated with Acquired Pure Red Cell Aplasia

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Sources for Acquired Pure Red Cell Aplasia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet