MCID: ACQ016
MIFTS: 18

Acquired Pure Red Cell Aplasia malady

Immune diseases, Blood diseases categories

Summaries for Acquired Pure Red Cell Aplasia

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42NIH Rare Diseases, 32MalaCards
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NIH Rare Diseases:42 Acquired pure red cell aplasia (prca) is a bone marrow disorder characterized by a reduction of red blood cells (erythrocytes) produced by the bone marrow. signs and symptoms may include fatigue, lethargy, and/or abnormal paleness of the skin (pallor) due to the anemia the caused by the disorder. in most cases, the cause of acquired prca is unknown (idiopathic). in other cases it may occur secondary to autoimmune disorders, tumors of the thymus gland (thymomas), hematologic cancers, solid tumors, viral infections, or certain drugs. treatment depends on the cause of the condition (if known) but often includes transfusions for individuals who are severely anemic and have cardiorespiratory failure. last updated: 12/14/2011

MalaCards: Acquired Pure Red Cell Aplasia, also known as adult pure red cell aplasia, is related to pure red-cell aplasia and transient erythroblastopenia of childhood. An important gene associated with Acquired Pure Red Cell Aplasia is EPO (erythropoietin). Affiliated tissues include skin, bone and bone marrow.

Aliases & Classifications for Acquired Pure Red Cell Aplasia

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42NIH Rare Diseases, 48Orphanet, 26ICD10 via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Immune diseases, Blood diseases


Aliases & Descriptions:

acquired pure red cell aplasia 42
adult pure red cell aplasia 42 48
idiopathic pure red cell aplasia 42
acquired prca 42


External Ids:

ICD10 via Orphanet26 D60.0
ICD1025 D60

Related Diseases for Acquired Pure Red Cell Aplasia

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17GeneCards, 18GeneDecks
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Diseases related to Acquired Pure Red Cell Aplasia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1pure red-cell aplasia11.1
2transient erythroblastopenia of childhood10.7
3enterocele10.5
4acquired thrombocytopenia10.3
5kidney disease10.3
6thymoma10.3

Graphical network of diseases related to Acquired Pure Red Cell Aplasia:



Diseases related to acquired pure red cell aplasia

Clinical Features for Acquired Pure Red Cell Aplasia

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Drugs & Therapeutics for Acquired Pure Red Cell Aplasia

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Acquired Pure Red Cell Aplasia

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Anatomical Context for Acquired Pure Red Cell Aplasia

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32MalaCards
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MalaCards organs/tissues related to Acquired Pure Red Cell Aplasia:

32
Skin, Bone, Bone marrow, Thymus

Animal Models for Acquired Pure Red Cell Aplasia or affiliated genes

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Publications for Acquired Pure Red Cell Aplasia

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Genetic Variations for Acquired Pure Red Cell Aplasia

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Expression for genes affiliated with Acquired Pure Red Cell Aplasia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Acquired Pure Red Cell Aplasia

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Pathways for genes affiliated with Acquired Pure Red Cell Aplasia

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Compounds for genes affiliated with Acquired Pure Red Cell Aplasia

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GO Terms for genes affiliated with Acquired Pure Red Cell Aplasia

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Products for genes affiliated with Acquired Pure Red Cell Aplasia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Acquired Pure Red Cell Aplasia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet