MCID: ACR015
MIFTS: 31

Acrocephalosyndactylia malady

Bone diseases category

Aliases & Classifications for Acrocephalosyndactylia

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Aliases & Descriptions for Acrocephalosyndactylia:

Name: Acrocephalosyndactylia 10 12
 
Apert Syndrome 10


Classifications:



External Ids:

Disease Ontology10 DOID:12960
ICD9CM29 755.55
MeSH36 D000168
NCIt42 C34348

Summaries for Acrocephalosyndactylia

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Wikipedia:68 Acrocephalosyndactylia (or acrocephalosyndactyly) is the common presentation of craniosynostosis and... more...

MalaCards based summary: Acrocephalosyndactylia, also known as apert syndrome, is related to apert syndrome and pfeiffer syndrome. An important gene associated with Acrocephalosyndactylia is FGFR2 (Fibroblast Growth Factor Receptor 2), and among its related pathways are Alzheimers Disease Pathway and Akt Signaling Pathway. Affiliated tissues include bone, and related mouse phenotypes are renal/urinary system and muscle.

Disease Ontology:10 A synostosis that results in craniosynostosis and syndactyly.

Related Diseases for Acrocephalosyndactylia

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Diseases related to Acrocephalosyndactylia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 59)
idRelated DiseaseScoreTop Affiliating Genes
1apert syndrome31.1FGF10, FGF2, FGFR1, FGFR2, FGFR3
2pfeiffer syndrome30.2FGF10, FGFR1, FGFR2, FGFR3, TWIST1
3crouzon syndrome29.5FGF13, FGF2, FGFR1, FGFR2, FGFR3, MSX2
4saethre-chotzen syndrome29.3ARID1B, FGFR1, FGFR2, FGFR3, MSX2, TWIST1
5syndactyly10.4
6craniosynostosis10.4
7polydactyly10.2
8polyhydramnios10.2
9omphalocele10.2
10synostosis10.2
11maroteaux fonfria syndrome10.2
12pfeiffer syndrome type 1, 2 and 310.2FGFR1, FGFR2
13p2y12 defect10.2FGFR3, TWIST1
14von economo's disease10.2FGFR2, FGFR3
15barbiturate abuse10.1FGFR2, FGFR3
16spinocerebellar ataxia 510.1FGFR1, FGFR2
17greig cephalopolysyndactyly syndrome10.1
18carpenter syndrome10.1
19gastroesophageal reflux10.1
20acne10.1
21congenital diaphragmatic hernia10.1
22choanal atresia10.1
23papillary carcinoma10.1
24obstructive sleep apnea10.1
25sleep apnea10.1
26strabismus10.1
27encephalocele10.1
28humeroradial synostosis10.1
29flna-related periventricular nodular heterotopia10.1FGFR1, FGFR2, FGFR3
30osteoglophonic dysplasia10.1FGFR1, FGFR2, FGFR3
31jackson-weiss syndrome10.1FGFR1, FGFR2, FGFR3
32neonatal abstinence syndrome10.1FGFR1, FGFR2, FGFR3
33beare-stevenson cutis gyrata syndrome10.1FGFR2, FGFR3, RAB23
34hypochondroplasia10.1FGFR1, FGFR2, FGFR3
35yellow nail syndrome10.1FGFR1, FGFR2, FGFR3
36achondroplasia10.0FGFR1, FGFR2, FGFR3
37syndromic intellectual disability10.0FGFR2, FGFR3, GLI3
38gonococcal iridocyclitis10.0FGFR2, FGFR3
39osteomalacia10.0FGF10, FGFR2
40achondrogenesis10.0FGF10, FGFR2
41grade iii astrocytoma10.0FGFR1, FGFR3, TWIST1
42plagiocephaly and x-linked mental retardation10.0FGFR1, FGFR2, FGFR3, TWIST1
43muenke syndrome10.0FGFR1, FGFR2, FGFR3, TWIST1
44osteodysplasia familial anderson type10.0FGF2, FGFR1, FGFR3
45slc16a1-related hyperinsulinism9.9FGFR2, FGFR3
46disease of mental health9.9FGF13, FGF2
47autosomal genetic disease9.9FGF10, FGFR2, FGFR3
48diaphragmatic eventration9.9MSX2, TWIST1
49asphyxiating thoracic dystrophy9.9FGF10, FGFR1, FGFR2, GLI3
50long bones of lower limb cancer9.9FGF13, FGF2, FGFR1

Graphical network of the top 20 diseases related to Acrocephalosyndactylia:



Diseases related to acrocephalosyndactylia

Symptoms for Acrocephalosyndactylia

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Drugs & Therapeutics for Acrocephalosyndactylia

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Drugs for Acrocephalosyndactylia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
TicagrelorapprovedPhase 3, Phase 2249274693-27-59871419
Synonyms:
(1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-D)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
AZD 6140
 
AZD-6140
AZD6140
Brilinta
2
Clopidogrelapproved, nutraceuticalPhase 3, Phase 2674120202-66-6, 113665-84-260606
Synonyms:
( )-(S)-Clopidogrel
(+)-(S)-Clopidogrel
(+)-Clopidogrel
(S)-Clopidogrel
(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
113665-84-2
AC-19024
AC1L1TKZ
AC1Q41I9
BIDD:GT0284
BRD-K27721098-065-02-9
BSPBio_003211
C16H16ClNO2S
CGE
CHEBI:37941
CHEMBL1771
CID60606
CLOPIDOGREL SULFATE
CPD000550475
Clopidogrel
Clopidogrel (INN)
Clopidogrel (TN)
Clopidogrel Bisulfate
Clopidogrel [BAN:INN]
Clopidogrel [Ban:Inn]
Clopidogrel [INN:BAN]
Clopidogrel bisulfate
Clopidogrel bisulphate
Clopidogrel sulfate
Clopidogrelum
D07729
DB00758
DivK1c_000787
HMS2090O21
HMS502H09
HSDB 7430
 
IDI1_000787
Isocover
KBio1_000787
KBio2_000545
KBio2_003113
KBio2_005681
KBio3_002431
KBioGR_000689
KBioSS_000545
LS-172232
MLS001165708
MLS001195633
MLS001304711
Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate
MolPort-002-885-817
MolPort-003-845-991
NCGC00163329-02
NINDS_000787
Plavix
Plavix (TN)
SAM002589956
SMR000550475
SPBio_000463
SR 25990
STK580572
STOCK5S-27782
Spectrum2_000512
Spectrum3_001606
Spectrum4_000175
Spectrum_000105
TL8000400
UNII-A74586SNO7
Zyllt
clopidogrel
clopidogrel, (+)(S)-isomer
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate
methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate
nchem.651-comp8
3
Eptifibatideapproved, investigationalPhase 228188627-80-7123610
Synonyms:
148031-34-9
157630-07-4
188627-80-7
2-[(3S,6S,12S,20R,23S)-20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid
2-[20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid
AC1L3WYY
AC1L9MDI
BIDD:GT0422
C35H49N11O9S2
C68-22
CHEBI:291902
CHEMBL1174
CID123610
CID448812
Eptifibatide
FT-0082227
 
HS-2011
I06-0351
Integrelin
Integrilin
Intrifiban
L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic (1-6)-disulfide
L-Cysteinamide,N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-propyl-,cyclic (1-6)-disulfide
LS-173318
LS-182837
N(6)-amidino-N(2)-(3-mercaptopropionyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide
N(sup 6)-Amidino-N(sup 2)-(3-mercaptopropionyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide
NCGC00167505-01
S(1),S(6)-cyclo[N(6)-carbamimidoyl-N(2)-(3-sulfanylpropanoyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide]
SB-1
Sch-60936
UNII-NA8320J834
[(3R,11S,17S,20S,25aS)-11-(4-carbamimidamidobutyl)-3-carbamoyl-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl]acetic acid
nchembio829-comp11
4
Heparinapproved, investigationalPhase 26729005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
5
TiclopidineapprovedPhase 218555142-85-35472
Synonyms:
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
55142-85-3
AC-15204
AC1L1KFB
BIDD:PXR0169
BPBio1_000191
BRD-K00603606-003-03-4
BRN 1216802
BSPBio_000173
C07140
C14H14ClNS
CAS-53885-35-1
CHEBI:9588
CHEMBL833
CID5472
D08594
DB00208
EINECS 259-498-5
HMS2089I18
L001108
LS-152434
MLS001201825
MolPort-002-507-849
 
NCGC00016872-01
NCGC00016872-02
NCGC00024361-04
PCR 5332
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
SMR000641861
SPBio_002094
STK589340
STOCK5S-54105
Ticlid
Ticlopidin-Puren
Ticlopidin-Puren (TN)
Ticlopidina
Ticlopidina [INN-Spanish]
Ticlopidine (INN)
Ticlopidine HCL
Ticlopidine Hydrochloride
Ticlopidine [INN:BAN]
Ticlopidinum
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
UNM-0000345023
ZINC19594599
ticlopidine
6
RivaroxabanapprovedPhase 2190366789-02-8
Synonyms:
BAY 59-7939
 
BAY59-7939
Xarelto
7
PrasugrelapprovedPhase 2160150322-43-36918456
Synonyms:
CS-747
Effient
Efient
 
Prasita
Prasugrel
Prasugrel Hydrochloride
SID124899264
cs-747
8
AspirinapprovedPhase 297150-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
7 Select Adult Chewable Aspirin
7 Select Aspirin
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Adult Chewable Low Dose Aspirin
Adult Low Dose Aspirin
Adult Low Dose Aspirin Enteric Safety Coated
Adult Low Dose Enteric Coated Aspirin
Adult Low Strength Aspirin
Aloxiprimum
Asacard
Asagran
Asaphen
Asatard
Ascoden-30
Ascriptin Maximum Strength Buffered Aspirin
Ascriptin Regular Strength Buffered Aspirin
Aspalon
Aspec
Aspergum
Aspi-cor
Aspir Low
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin 81 Mg
Aspirin 81 Mg Low Dose
Aspirin Adult Low Dose
Aspirin Adult Low Strength
Aspirin Adult Low Strength Aspirin
Aspirin Adult low strength
Aspirin Chewable Low Dose
Aspirin Delayed Release
Aspirin EC
Aspirin EXTRA STRENGTH
Aspirin Ec
Aspirin Enteric
Aspirin Enteric Coated
Aspirin Enteric Coated Low Dose
Aspirin Enteric Safety Coated
Aspirin Enteric Safety-Coated
Aspirin Low Dose
Aspirin Low Dose Chewable
Aspirin Low Dose Enteric Coated
Aspirin Low Dose Safety Coated
Aspirin Low Strength
Aspirin Nsaid
Aspirin Regular Strength
Aspirin Regular Strength regular strength
Aspirin Regular strength
Aspirin Safety Coated
Aspirin Safety Coated Adult Low Dose
Aspirin Safety coated
Aspirin Thin coated
Aspirin [BAN:JAN]
Aspirin adult low dose
Aspirin adult low strength
Aspirin enteric safety coated
Aspirin low dose
Aspirin low dose chewable
Aspirin low dose enteric coated
Aspirin regular strength
Aspirina 03
Aspirine
Aspiring
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Advanced Aspirin Extra Strength
Bayer Advanced Aspirin Regular Strength
Bayer Aspirin 8 Hour
Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange
Bayer Aspirin Regimen Regular Strength
Bayer Buffered
Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavored
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Fast Release
Bayer Genuine Aspirin
Bayer Low Dose
Bayer Plus
Bayer Plus Extra Strength
Bayer Womens
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Buffered Aspirin
Bufferin
Bufferin LOW DOSE BUFFERED ASPIRIN
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Care One Aspirin
Cemirit
Chewable Adult Low Dose Aspirin
Chewable Aspirin
Chewable Low Dose Aspirin
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Critical Care Aspirin To Go
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dg Health Aspirin
Direct Safety Aspirin
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ec-81aspirin Enteric Coated
Ecolen
Ecotrin
Ecotrin Regular Strength
Empirin
Empirin with Codeine
Endosprin
Endydol
Enteric Aspirin
Enteric Coated Aspirin
Enteric Coated Aspirin Regular Strength
Enteric Coated Aspirin Regular strength
Enteric Coated Aspirin regular strength
Enteric Coated Asprin 81 Mg
Enteric Coated Low Dose Aspirin
 
Enteric Safety Coated Aspirin
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Equaline Aspirin
Equaline Aspirin adult low dose
Equate Aspirin
Equate Aspirin chewable
Extren
Fasprin
Flanax Aspirin Pain Reliever
Formucare Aspirin
Genuine Aspirin
Globentyl
Globoid
Good Neighbor Pharmacy Aspirin
Good Neighbor Pharmacy Aspirin Enteric Safety Coated
Good Neighbor Pharmacy Aspirin orange flavor chewable
Good Sense Aspirin
Good Sense Aspirin Enteric Safety Coated
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Handy Solutions Genuine Aspirin Bayer
Health Mart Aspirin
Health Mart Regular Strength Enteric Coated Aspirin
Health Sense Adult Chewable Low Strength Aspirin
Health Sense Aspirin 81
Health Sense Ecpirin
Healthy Accents Aspirin
Helicon
Henry Schein Aspirin
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kroger Value Aspirin
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Leader Aspirin
Leader Cardinal Health Aspirin
Leader Low Dose Aspirin
Levius
Lopac-A-5376
Lopac0_000038
Low Dose Adult Aspirin
Low Dose Aspirin
Low Dose Aspirin 81 Mg Safety Coated
Low Dose Aspirin Enteric Safety Coated
Low Dose Asprin
Low Dose Chewable Aspirin
Low Dose Miniprin Enteric Safety Coated
Low Dose Pain Relief Aspirin
Low Strength Chewable Aspirin
Low-dose Aspirin
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medi First Plus Aspirin
Medi-first Aspirin
Medique Aspirin
Medisyl
Micristin
Micro-coated Aspirin
Miniprin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
North Aspirin
Novasen
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Pain Relief Aspirin
Pain Relief Aspirin Low Dose
Persistin
Pharbest Aspirin 325mg
Pharbest Regular Strength Aspirin
Pharmacin
Pirseal
Plus Pharma NSAID 325 mg
Plus Pharma Nsaid Aspirin
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rapid Comfort Aspirin
Regular Strength Aspirin
Regular Strength Aspirin Ec
Regular Strength Buffered Aspirin
Regular Strength Enteric Aspirin
Regular Strength Enteric Coated Aspirin
Regular Strength Pain Relief
Regular Strength Tri-buffered Aspirin
Rexall Aspirin
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
Rugby Aspirin
Rx Act Aspirin
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Safety Coated Aspirin
Safety Coated Enteric Aspirin
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Smart Health Aspirin regular strength
Smart Sense Aspirin
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Solves - Aspirin Cherry
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
St. Joseph Chewable Aspirin
St. Joseph Safety Coated Aspirin
Sunmark Aspirin
Sunmark Aspirin Regular Strength
Sunmark Aspirin adult low strength
Sunmark Aspirin low dose
Supac
Tasprin
Temperal
Toldex
Topcare Aspirin
Tri-buffered Aspirin
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Uncoated Aspirin
Value Pharma Aspirin Pain Reliever
Value Pharmapain Reliever Extra Strength
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
Zee Aspirin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
9Calcium, DietaryPhase 23529
10calcium heparinPhase 2672
11
Amlodipineapproved43188150-42-92162
Synonyms:
()-Amlodipine
(RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)
3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(O-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (.+/-.)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
88150-42-9
88150-47-4 (maleate (1:1))
AC-4535
AC1L1D26
AC1Q32ZS
AMLODIPINE BASE
AMVAZ
Ambap88150-42-9
Amlocard
Amlodipine
Amlodipine (INN)
Amlodipine Benzenesulfonate
Amlodipine Besilate
Amlodipine Besylate
Amlodipine Free Base
Amlodipine Maleate
Amlodipine [INN:BAN]
Amlodipine besilate
Amlodipine besylate
Amlodipine free base
Amlodipino
Amlodipino [Spanish]
Amlodipinum
Amlodipinum [Latin]
Amlodis
Amlopres
Amlor
 
Amvaz
BIDD:GT0810
BRD-A22032524-074-02-4
BRD-A22032524-074-03-2
BSPBio_002727
C06825
CHEBI:2668
CHEMBL1491
CID2162
CPD000469198
Coroval
D07450
DB00381
HMS2052N03
HMS2089H07
I14-0798
Intervask
Istin
KBio3_001947
KBioGR_001643
LS-131183
Lipinox
Lotrel
MLS001401409
MolPort-001-792-963
NCGC00165957-01
NCGC00165957-02
NCGC00165957-03
Norvasc
Norvasc (TN)
Pelmec
R,S)-Amlodipine
Racemic Amlodipine
SAM001246705
SMR000469198
SPBio_000351
Spectrum2_000486
Spectrum3_001004
Spectrum4_001132
Spectrum5_001550
UK-4834011
UNII-1J444QC288
amlodipine

Interventional clinical trials:

idNameStatusNCT IDPhase
1Safety and Efficacy of Low-Dose Ticagrelor in Chinese Patients With NSTE-ACSRecruitingNCT02415803Phase 3
2Feasibility Assessment of ACS CatheterWithdrawnNCT01960517Phase 2, Phase 3
3Study of Otamixaban Versus Unfractionated Heparin (UFH) and Eptifibatide in Non-ST Elevation Acute Coronary SyndromeCompletedNCT00317395Phase 2
4A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary SyndromeRecruitingNCT02293395Phase 2
5PCI and Renal Denervation in Hypertensive Patients With Acute Coronary SyndromesNot yet recruitingNCT02272920Phase 2
6Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial DifferencesCompletedNCT00340964
7Dairy Products and Metabolic Effects (Norwegian Part)CompletedNCT00140816
8Azilsartan Circadian and Sleep PressureCompletedNCT01762501
9European Quality Improvement Programme for Acute Coronary SyndromesRecruitingNCT00716430

Search NIH Clinical Center for Acrocephalosyndactylia

Genetic Tests for Acrocephalosyndactylia

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Anatomical Context for Acrocephalosyndactylia

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MalaCards organs/tissues related to Acrocephalosyndactylia:

33
Bone

Animal Models for Acrocephalosyndactylia or affiliated genes

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MGI Mouse Phenotypes related to Acrocephalosyndactylia:

38 (show all 15)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.9FGF10, FGFR1, FGFR2, FGFR3, GLI3
2MP:00053697.9FGF10, FGF2, FGFR1, FGFR2, MSX2, TWIST1
3MP:00053827.9FGF10, FGFR1, FGFR2, FGFR3, GLI3, MSX2
4MP:00053817.8FGF10, FGFR1, FGFR2, FGFR3, GLI3, MSX2
5MP:00053807.7FGF10, FGFR1, FGFR2, GLI3, MSX2, RAB23
6MP:00053777.7FGF10, FGF2, FGFR1, FGFR2, FGFR3, GLI3
7MP:00053857.6FGF10, FGF2, FGFR1, FGFR2, GLI3, MSX2
8MP:00053717.5FGF10, FGFR1, FGFR2, FGFR3, GLI3, MSX2
9MP:00107717.5FGF10, FGFR1, FGFR2, FGFR3, GLI3, MSX2
10MP:00053847.5FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
11MP:00053917.0FGF10, FGF2, FGFR1, FGFR2, FGFR3, GLI3
12MP:00053907.0FGF10, FGF2, FGFR1, FGFR2, FGFR3, GLI3
13MP:00053866.8FGF13, FGF2, FGFR1, FGFR2, FGFR3, MSX2
14MP:00107686.7FGF10, FGF2, FGFR1, FGFR2, FGFR3, GLI3
15MP:00036316.0FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3

Publications for Acrocephalosyndactylia

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Articles related to Acrocephalosyndactylia:

idTitleAuthorsYear
1
Acrocephalosyndactylia associated with a chromosomal translocation. 46,XX, t (2p-; Cq+). (5493837)
1970
2
Acrocephalosyndactylia: two case reports. (13594964)
1958

Variations for Acrocephalosyndactylia

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Expression for genes affiliated with Acrocephalosyndactylia

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Search GEO for disease gene expression data for Acrocephalosyndactylia.

Pathways for genes affiliated with Acrocephalosyndactylia

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Pathways related to Acrocephalosyndactylia according to GeneCards Suite gene sharing:

(show all 44)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4FGFR1, FGFR2, FGFR3
29.4FGFR1, FGFR2, FGFR3
39.4FGFR1, FGFR2, FGFR3
4
Angiogenesis (WikiPathways)
Show member pathways
9.0FGFR1, FGFR2, FGFR3
59.0FGF13, FGF2, FGFR2
69.0FGF13, FGF2, FGFR1
79.0FGF13, FGF2, FGFR1
89.0FGF13, FGF2, FGFR1
99.0FGF13, FGF2, FGFR1
108.7FGF13, FGF2, FGFR1, TWIST1
11
Show member pathways
8.3FGF13, FGF2, FGFR1, FGFR2, FGFR3
12
Angiogenesis (CST)
Show member pathways
8.3FGF13, FGF2, FGFR1, FGFR2, FGFR3
138.3FGF13, FGF2, FGFR1, FGFR2, FGFR3
148.3FGF13, FGF2, FGFR1, FGFR2, FGFR3
158.3FGF13, FGF2, FGFR1, FGFR2, FGFR3
168.3FGF13, FGF2, FGFR1, FGFR3, GLI3
17
Show member pathways
8.2FGF10, FGF13, FGF2, FGFR1, FGFR2
18
Show member pathways
8.1FGF10, FGF13, FGF2, FGFR2, FGFR3
19
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
20
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
21
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
22
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
23
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
24
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
25
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
26
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
27
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
28
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
29
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
30
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
31
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
32
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
33
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
347.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
35
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
36
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
377.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
38
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
39
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
40
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
41
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
42
Show member pathways
7.8FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
437.5FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
447.1FGF13, FGF2, FGFR1, FGFR2, FGFR3, MSX2

GO Terms for genes affiliated with Acrocephalosyndactylia

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Cellular components related to Acrocephalosyndactylia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.5FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
2nucleusGO:00056346.3ARID1B, FGF10, FGF13, FGF2, FGFR1, FGFR2

Biological processes related to Acrocephalosyndactylia according to GeneCards Suite gene sharing:

(show top 50)    (show all 98)
idNameGO IDScoreTop Affiliating Genes
1orbitofrontal cortex developmentGO:002176910.6FGFR1, FGFR2
2ventricular zone neuroblast divisionGO:002184710.6FGFR1, FGFR2
3fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex developmentGO:003560710.6FGFR1, FGFR2
4spinal cord dorsal/ventral patterningGO:002151310.5GLI3, RAB23
5positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathwayGO:009008010.5FGFR1, FGFR3
6fibroblast growth factor receptor signaling pathway involved in mammary gland specificationGO:006059510.4FGF10, FGFR2
7mammary gland bud formationGO:006061510.4FGF10, FGFR2
8epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.4FGF10, FGFR2
9branch elongation involved in salivary gland morphogenesisGO:006066710.4FGF10, FGFR2
10mesenchymal cell differentiation involved in lung developmentGO:006091510.4FGF10, FGFR2
11mammary gland specificationGO:006059410.4FGF10, GLI3
12regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signalingGO:006066510.3FGF10, FGFR1
13cranial suture morphogenesisGO:006036310.1MSX2, TWIST1
14frontal suture morphogenesisGO:006036410.1GLI3, MSX2
15embryonic digestive tract morphogenesisGO:004855710.0FGF10, FGFR2, GLI3
16positive regulation of cardiac muscle cell proliferationGO:006004510.0FGF2, FGFR1, FGFR2
17positive regulation of phospholipase activityGO:001051810.0FGFR1, FGFR2, FGFR3
18branching involved in salivary gland morphogenesisGO:006044510.0FGF10, FGFR1, FGFR2
19regulation of smoothened signaling pathwayGO:00085899.9FGF10, FGFR2, RAB23
20negative regulation of cell differentiationGO:00455969.9FGF10, GLI3, TWIST1
21endochondral bone growthGO:00034169.9FGFR3, MSX2
22organ inductionGO:00017599.8FGF10, FGF2, FGFR1
23in utero embryonic developmentGO:00017019.7FGFR1, FGFR2, GLI3, TWIST1
24odontogenesisGO:00424769.7FGFR2, MSX2, TWIST1
25positive regulation of MAPK cascadeGO:00434109.5FGF10, FGFR1, FGFR2, FGFR3
26bone morphogenesisGO:00603499.4FGFR2, FGFR3, MSX2
27positive regulation of epithelial cell proliferationGO:00506799.4FGF10, FGF2, FGFR2, TWIST1
28positive regulation of osteoblast differentiationGO:00456699.4FGF2, GLI3, MSX2
29angiogenesisGO:00015259.3FGF10, FGF2, FGFR1, FGFR2
30positive regulation of canonical Wnt signaling pathwayGO:00902639.2FGF10, FGF2, FGFR2, FGFR3
31embryonic digit morphogenesisGO:00427339.2GLI3, MSX2, RAB23, TWIST1
32embryonic limb morphogenesisGO:00303269.2FGFR1, GLI3, MSX2, TWIST1
33positive regulation of ERK1 and ERK2 cascadeGO:00703749.1FGF10, FGF2, FGFR2, FGFR3
34lung developmentGO:00303249.0FGF10, FGF2, FGFR1, FGFR2, GLI3
35phosphatidylinositol-mediated signalingGO:00480158.9FGF10, FGF2, FGFR1, FGFR2, FGFR3
36positive regulation of cell proliferationGO:00082848.9FGF10, FGF2, FGFR1, FGFR2, FGFR3
37activation of MAPKK activityGO:00001868.8FGF10, FGF2, FGFR1, FGFR2, FGFR3
38Ras protein signal transductionGO:00072658.7FGF10, FGF2, FGFR1, FGFR2, FGFR3
39insulin receptor signaling pathwayGO:00082868.7FGF10, FGF2, FGFR1, FGFR2, FGFR3
40fibroblast growth factor receptor signaling pathwayGO:00085438.7FGF10, FGF2, FGFR1, FGFR2, FGFR3
41Fc-epsilon receptor signaling pathwayGO:00380958.7FGF10, FGF2, FGFR1, FGFR2, FGFR3
42neurotrophin TRK receptor signaling pathwayGO:00480118.7FGF10, FGF2, FGFR1, FGFR2, FGFR3
43wound healingGO:00420608.5FGF10, FGF2, GLI3, MSX2
44epidermal growth factor receptor signaling pathwayGO:00071738.5FGF10, FGF2, FGFR1, FGFR2, FGFR3
45vascular endothelial growth factor receptor signaling pathwayGO:00480108.3FGF10, FGF2, FGFR1, FGFR2, FGFR3
46MAPK cascadeGO:00001658.1FGF10, FGF13, FGF2, FGFR1, FGFR2, FGFR3
47negative regulation of cell proliferationGO:00082858.1FGF10, FGF2, FGFR2, FGFR3, GLI3, MSX2
48axon guidanceGO:00074118.1FGF10, FGF2, FGFR1, FGFR2, FGFR3, GLI3
49negative regulation of transcription from RNA polymerase II promoterGO:00001228.0FGFR1, FGFR2, FGFR3, GLI3, MSX2, TWIST1
50small GTPase mediated signal transductionGO:00072647.7FGF10, FGF2, FGFR1, FGFR2, FGFR3, RAB23

Molecular functions related to Acrocephalosyndactylia according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1fibroblast growth factor receptor bindingGO:000510410.0FGF10, FGF2
2fibroblast growth factor-activated receptor activityGO:000500710.0FGFR1, FGFR2, FGFR3
3fibroblast growth factor bindingGO:00171349.9FGFR1, FGFR2, FGFR3
4chemoattractant activityGO:00420569.5FGF10, FGF2
5protein tyrosine kinase activityGO:00047139.4FGFR1, FGFR2, FGFR3
6heparin bindingGO:00082018.8FGF10, FGF2, FGFR1, FGFR2
7growth factor activityGO:00080838.7FGF10, FGF13, FGF2

Sources for Acrocephalosyndactylia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet