MCID: ACR005
MIFTS: 34

Acrodermatitis malady

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Acrodermatitis

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Aliases & Descriptions for Acrodermatitis:

Name: Acrodermatitis 11 47 38 13 67

Classifications:



External Ids:

Disease Ontology11 DOID:2722
MeSH38 D000169
SNOMED-CT61 8197001
NCIt44 C84532

Summaries for Acrodermatitis

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Wikipedia:70 Acrodermatitis /ac·ro·der·ma·ti·tis/ is a childhood form of dermatitis selectively affecting the... more...

MalaCards based summary: Acrodermatitis is related to acrodermatitis enteropathica and acrodermatitis chronica atrophicans. An important gene associated with Acrodermatitis is SLC39A4 (Solute Carrier Family 39 Member 4). Affiliated tissues include skin, breast and liver, and related mouse phenotypes are liver/biliary system and endocrine/exocrine gland.

Disease Ontology:11 A dermatitis that selectively affects the hands and feet.

Related Diseases for Acrodermatitis

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Diseases related to Acrodermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 118)
idRelated DiseaseScoreTop Affiliating Genes
1acrodermatitis enteropathica12.4
2acrodermatitis chronica atrophicans12.4
3acrodermatitis continua suppurativa of hallopeau11.9
4gianotti crosti syndrome11.6
5psoriasis 14, pustular11.5
6enteropathica10.8
7zinc deficiency, transient neonatal10.8
8psoriasis susceptibility 110.8
9nephronophthisis10.3ALB, IL36RN
10postencephalitic parkinson disease10.3ALB, CD40LG
11marek disease10.3ALB, CD40LG
12testicular brenner tumor10.3ALB, CD40LG
13adie pupil10.3ALB, CD40LG
14mesangial proliferative glomerulonephritis10.3ALB, CD40LG
15scleral disease10.3ALB, CD40LG
16splenic infarction10.3ALB, CD40LG
17smoldering myeloma10.3ALB, CD40LG
18chromoblastomycosis10.3ALB, CD40LG
19spastic monoplegia10.3ALB, CD40LG
20pyrimidine metabolic disorder10.3ALB, CD40LG
21sweat gland cancer10.3ALB, CD40LG
22balantidiasis10.3ALB, CD40LG
23fibrous histiocytoma10.3ALB, CD40LG
24autoimmune disease of cardiovascular system10.3ALB, CD40LG
2510.2ALB, CXCL10
26adenocarcinoma10.2ALB, CD40LG
27pancreatic vasoactive intestinal peptide producing tumor10.2ALB, CD40LG
28chronic apical periodontitis10.2ALB, CD40LG
29achilles bursitis10.2ALB, CD40LG
30loin pain hematuria syndrome10.2CD40LG, IL36RN
31sarcoid meningitis10.2ALB, CD40LG
32ascending cholangitis10.2ALB, CD40LG
33lymphopenia10.2ALB, CD40LG
34bartter disease10.2ALB, CD40LG
35rocky mountain spotted fever10.2CD40LG, CXCL10
36eczematous dermatitis of eyelid10.2ALB, CD40LG
37alternating exotropia10.2ALB, CD40LG
38small intestine leiomyoma10.2CD40LG, CXCL10
39arcus senilis10.2ALB, CD40LG
40uterine corpus dissecting leiomyoma10.2ALB, CD40LG
41lipid storage disease10.2ALB, CD40LG
42dentin dysplasia10.2CD40LG, CXCL10
43mixed lacrimal gland cancer10.1ALB, CD40LG
44binocular vision disease10.1CD40LG, CXCL10
45membranoproliferative glomerulonephritis10.1CD40LG, CXCL10
46laryngeal tuberculosis10.1ALB, CD40LG
47sheehan syndrome10.1ALB, CD40LG
48progressive relapsing multiple sclerosis10.1CD40LG, CXCL10
49central pontine myelinolysis10.1ALB, CD40LG
50congenital disorder of glycosylation, type ih10.1ALB, CD40LG

Graphical network of the top 20 diseases related to Acrodermatitis:



Diseases related to acrodermatitis

Symptoms for Acrodermatitis

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Drugs & Therapeutics for Acrodermatitis

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Drugs for Acrodermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Zincapproved22317440-66-632051, 23994
Synonyms:
30Zn
Cinc
Zinc
Zinc ion
 
Zincum
Zink
Zn
Zn(ii)
Zn2+
2
Doxycyclineapproved, investigational, vet_approved237564-25-054671203
Synonyms:
(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
10597-92-9
17086-28-1 (mono-hydrate)
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)
24390-14-5
41411-66-9 (6-epimer, mono-hydrochloride)
5-Hydroxy-alpha-6-deoxytetracycline
5-hydroxy-α-6-deoxytetracycline
564-25-0
6-Deoxyoxytetracycline
6-Deoxytetracycline
6-alpha-Deoxy-5-oxytetracycline
6-alpha-deoxy-5-oxytetracycline
69935-17-7 (mono-hydrochloride, di-hydrate)
6alpha-Deoxy-5-oxytetracycline
6alpha-deoxy-5-oxytetracycline
6α-deoxy-5-oxytetracycline
7164-70-7
7264-10-0
94088-85-4 (calcium salt (1:2))
AB08 (*Fosfatex)
AC1NQXW7
AC1NS4CW
AC1NUYS8
AC1O8PYM
Alti-Doxycycline
Anhydrous doxycycline
Apo-Doxy
Atridox
Azudoxat
BCBcMAP01_000024
BIDD:GT0146
BMY-28689
BPBio1_000951
BSPBio_000863
BSPBio_001936
BU-3839T
C06973
CHEBI:50845
CHEMBL1433
CID5281011
CID5353597
CID5463943
CID6713981
CPD001550033
D07876
DB00254
DMSC (*Fosfatex)
DOXCYCLINE ANHYDROUS
DOXY
DOXYCYCLINE CALCIUM
DOXYCYCLINE MONOHYDRATE
Deoxymykoin
DivK1c_000345
Dossiciclina
Dossiciclina [DCIT]
Doxcycline anhydrous
Doxiciclina
Doxiciclina [INN-Spanish]
Doxiciclina [Italian]
Doxitard
Doxivetin
Doxy-Caps
Doxy-Puren
Doxy-Tabs
Doxycen
Doxychel
Doxychel (TN)
Doxycin
Doxycyclin
Doxycycline (200mg/day) or Placebo
 
Doxycycline (INN)
Doxycycline (TN)
Doxycycline (anhydrous)
Doxycycline (internal use)
Doxycycline Hyclate
Doxycycline Monohydrate
Doxycycline anhydrous
Doxycycline hyclate
Doxycycline-Chinoin
Doxycyclinum
Doxycyclinum [INN-Latin]
Doxysol
Doxytec
Doxytetracycline
EINECS 209-271-1
GS-3065 (*monohydrate)
HMS2090E06
HSDB 3071
Hydramycin
IDI1_000345
Investin
Jenacyclin
KBio1_000345
KBio2_001287
KBio2_003855
KBio2_006423
KBio3_001156
KBioGR_001133
KBioSS_001287
LS-187766
LS-93868
Liviatin
Lopac0_000405
MolPort-002-507-423
Monodox
Monodox (*monohydrate)
NCGC00161602-01
NCGC00161602-03
NCGC00161602-04
NCGC00167961-01
NCGC00179395-01
NINDS_000345
NSC633557
Novo-Doxylin
Nu-Doxycycline
Oracea
Prestwick0_000852
Prestwick1_000852
Prestwick2_000852
Prestwick3_000852
Ronaxan
SAM002589932
SMP1_000107
SPBio_000246
SPBio_002784
STOCK1N-34341
Spanor
Spectrum2_000143
Spectrum3_000408
Spectrum4_000527
Spectrum5_000947
Spectrum_000807
Supracyclin
UNII-334895S862
UPCMLD-DP021
UPCMLD-DP021:001
Vibra-tabs
Vibramycin
Vibramycin (*monohydrate)
Vibramycin Novum
Vibramycine
Vibravenos
Vivox (*Hyclate)
alpha-6-Deoxy-5-hydroxytetracycline
alpha-6-Deoxyoxytetracycline
alpha-Doxycycline
doxycycline
3Antiparasitic Agents2127
4Antiprotozoal Agents1986
5Antimalarials1216
6Anti-Bacterial Agents10884
7Anti-Infective Agents21402

Interventional clinical trials:

idNameStatusNCT IDPhase
1Genetic Study of Severe Zinc DeficienciesCompletedNCT02870166
2Laboratory Characteristics in Chronic Atrophic AcrodermatitisRecruitingNCT02147262
3Borrelia Species in Cutaneous Lyme BorreliosisRecruitingNCT00576082

Search NIH Clinical Center for Acrodermatitis


Cochrane evidence based reviews: acrodermatitis

Genetic Tests for Acrodermatitis

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Anatomical Context for Acrodermatitis

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MalaCards organs/tissues related to Acrodermatitis:

35
Skin, Breast, Liver, Bone, T cells, Lymph node, Pancreas

Animal Models for Acrodermatitis or affiliated genes

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MGI Mouse Phenotypes related to Acrodermatitis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.9ALB, OTC, PLIN2, SLC39A4
2MP:00053798.4ALB, CD40LG, OTC, PLIN2, SLC39A4
3MP:00107687.6ALB, CD40LG, CXCL10, IL36RN, OTC, SLC39A4
4MP:00053767.5ALB, CD40LG, CXCL10, IL36RN, OTC, PLIN2

Publications for Acrodermatitis

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Articles related to Acrodermatitis:

(show top 50)    (show all 596)
idTitleAuthorsYear
1
Acrodermatitis chronica atrophicans-probably an overlooked differential diagnosis for arthritis. (27818388)
2016
2
Ferdinando Gianotti and the papular acrodermatitis of childhood: a scientist against all the odds. (24827010)
2014
3
A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity. (22737083)
2012
4
Gray hair and acrodermatitis enteropathica-like dermatitis: an unexpected presentation of cystic fibrosis. (21424670)
2011
5
Acrodermatitis enteropathica: a review of 29 Tunisian cases. (20883266)
2010
6
Acrodermatitis chronica atrophicans: a case report and review of the literature. (20540415)
2010
7
Novel proteolytic processing of the ectodomain of the zinc transporter ZIP4 (SLC39A4) during zinc deficiency is inhibited by acrodermatitis enteropathica mutations. (18936158)
2009
8
Excellent and prolonged response to infliximab in a case of recalcitrant acrodermatitis continua of Hallopeau. (18785890)
2009
9
Acrodermatitis enteropathica in a full-term exclusively breast-fed infant. (18424385)
2008
10
Acrodermatitis enteropathica-like simulating severe atopic dermatitis: a case report. (18680706)
2008
11
Identification of a unique splice site variant in SLC39A4 in bovine hereditary zinc deficiency, lethal trait A46: An animal model of acrodermatitis enteropathica. (16714095)
2006
12
Acrodermatitis enteropathica-like eruption associated with combined nutritional deficiency. (16224175)
2005
13
Acquired syndactyly secondary to acrodermatitis continua of Hallopeau. (15888186)
2005
14
Successful treatment of acrodermatitis continua of Hallopeau by the tumour necrosis factor-alpha inhibitor infliximab (Remicade). (14996123)
2004
15
Acrodermatitis continua of Hallopeau: was it an outcome of a surgical trauma or initially misdiagnosed as onychomycosis? (12705767)
2003
16
Using oral tetracycline and topical betamethasone valerate to treat acrodermatitis continua of hallopeau. (12234156)
2002
17
Joint and bone involvement in Dutch patients with Lyme borreliosis presenting with acrodermatitis chronica atrophicans. (10048289)
1999
18
Peripheral neuropathy in acrodermatitis chronica atrophicans - a late Borrelia manifestation. (9228267)
1997
19
The acrodermatitis enteropathica mutation transiently affects zinc metabolism in human fibroblasts. (8558304)
1996
20
Acrodermatitis enteropathica-like eruption during treatment of maple syrup urine disease: report of one case. (8942030)
1996
21
Success and failure in the treatment of acrodermatitis chronica atrophicans. (8852478)
1996
22
Lymphoproliferative responses to Borrelia burgdorferi in patients with erythema migrans, acrodermatitis chronica atrophicans, lymphadenosis benigna cutis, and morphea. (7778918)
1995
23
Hallopeau's acrodermatitis continua of the nail apparatus: a clinical and pathological study of 20 patients. (7908489)
1994
24
Acrodermatitis chronica atrophicans involving the face. Evidence for Borrelia burgdorferi infection confirmed by DNA amplification. (7873838)
1994
25
Acrodermatitis chronica atrophicans in the United States: clinical and histopathologic features of six cases. (7956339)
1994
26
Serological follow-up after treatment of Borrelia arthritis and acrodermatitis chronica atrophicans. (7939435)
1994
27
Lyme borreliosis presenting as acrodermatitis chronica atrophicans. (1579190)
1992
28
Topically administered fluorouracil in acrodermatitis continua of Hallopeau. (1986705)
1991
29
Long chain fatty acids in serum phospholipids in acrodermatitis enteropathica before and after zinc treatment: a case report. (3392358)
1988
30
Successful cultivation of spirochetes from skin lesions of patients with erythema chronicum migrans Afzelius and acrodermatitis chronica atrophicans. (4013743)
1985
31
Picolinic acid in acrodermatitis enteropathica: evidence for a disorder of tryptophan metabolism. (6694049)
1984
32
Serum and hair zinc as predictors of clinical symptoms in acrodermatitis enteropathica. (6429442)
1984
33
Maternal essential fatty acid supplementation increases zinc absorption in neonatal rats: relevance to the defect in zinc absorption in acrodermatitis enteropathica. (7110781)
1982
34
Papular acrodermatitis (Gianotti-Crosti syndrome) in a child with anicteric hepatitis B, virus subtype adw. (7097415)
1982
35
Is acrodermatitis enteropathica related to the absence of zinc binding ligand in bovine milk? (570352)
1979
36
The acrodermatitis enteropathica-like syndrome. (109049)
1979
37
Acrodermatitis enteropathica--a zinc deficiency state. (675401)
1978
38
Gluconate zinc in acrodermatitis enteropathica. (773310)
1976
39
Letter: Acrodermatitis enteropathica and cellular immune deficiency. (57499)
1976
40
Treatment of acrodermatitis enteropathica with zinc sulfate. (776091)
1976
41
Reversible intestinal mucosal abnormality in acrodermatitis enteropathica. (952555)
1976
42
Letter: Exacerbation of acrodermatitis enteropathica by soya-bean milk feeding. (52794)
1975
43
Tryptophan metabolsim and serum fatty acids in acrodermatitis enteropathica. (4407531)
1974
44
Ultrastructural findings in acrodermatitis enteropathica. (4359206)
1974
45
Agammaglobulinemia with B lymphocytes in a neonate with acrodermatitis enteropathica. (4546718)
1974
46
Iatrogenic, corticosteroid-induced acrodermatitis chronica atrophicans. (4682654)
1973
47
Case for diagnosis: acrodermatitis enteropathica vs sebopsoriasis. (4248273)
1970
48
Acrodermatitis enteropathica. Report of a case in a twin with dramatic response to expressed human milk. (5318960)
1965
49
Infantile lichenoid acrodermatitis. Report of a case of Gianotti-Crosti syndrome. (5835329)
1965
50
Acrodermatitis enteropathica; report of two additional cases. (18101569)
1948

Variations for Acrodermatitis

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Expression for genes affiliated with Acrodermatitis

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Search GEO for disease gene expression data for Acrodermatitis.

Pathways for genes affiliated with Acrodermatitis

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GO Terms for genes affiliated with Acrodermatitis

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Cellular components related to Acrodermatitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.6ALB, CD40LG, CXCL10, IL36RN

Sources for Acrodermatitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet