MCID: ACT093
MIFTS: 29

Actinic Cheilitis malady

Rare diseases category
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Summaries for Actinic Cheilitis

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Sources:
65Wikipedia, 33MalaCards
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Wikipedia:65 Actinic cheilitis (also known as \"actinic cheilosis\", \"sailor\'s lip\"), is a form of cheilitis which... more...

MalaCards: Actinic Cheilitis, also known as actinic cheilosis, is related to cheilitis and acne. An important gene associated with Actinic Cheilitis is CD1A (CD1a molecule), and among its related pathways are Cell adhesion molecules (CAMs) and CD28 co-stimulation. The compounds tamoxifen and aspirin have been mentioned in the context of this disorder. Affiliated tissues include skin and salivary gland, and related mouse phenotype skeleton.

Aliases & Classifications for Actinic Cheilitis

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43NIH Rare Diseases, 62UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Aliases & Descriptions:

actinic cheilitis 43 62
actinic cheilosis 43


Related Diseases for Actinic Cheilitis

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Actinic Cheilitis:



Diseases related to actinic cheilitis

Symptoms for Actinic Cheilitis

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Drugs & Therapeutics for Actinic Cheilitis

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Actinic Cheilitis

Search NIH Clinical Center for Actinic Cheilitis

Genetic Tests for Actinic Cheilitis

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Anatomical Context for Actinic Cheilitis

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33MalaCards
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MalaCards organs/tissues related to Actinic Cheilitis:

33
Skin, Salivary gland

Animal Models for Actinic Cheilitis or affiliated genes

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Sources:
37MGI
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MGI Mouse Phenotypes related to Actinic Cheilitis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.8CD274, PDCD1, CHKB

Publications for Actinic Cheilitis

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52PubMed
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Articles related to Actinic Cheilitis:

(show top 50)    (show all 102)
idTitleAuthorsYear
1
Erbium laser resurfacing for actinic cheilitis. (24196339)
2013
2
Oral medicine case book 51: actinic cheilitis in a patient with oculocutaneous albinism. (23971281)
2013
3
Photodynamic therapy in actinic cheilitis: clinical and anatomopathological evaluation of 19 patients. (22714758)
2012
4
Methyl-aminolevulinate photodynamic therapy for the treatment of actinic cheilitis: a retrospective evaluation of 29 patients. (22370573)
2012
5
Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects. (22481658)
2012
6
Immunohistochemical analysis of p53, APE1, hMSH2 and ERCC1 proteins in actinic cheilitis and lip squamous cell carcinoma. (21323960)
2011
7
Altered I^-catenin expression related to cancer progression on actinic cheilitis and squamous cell carcinoma of the lip. (20970365)
2011
8
Sequential use of photodynamic therapy and imiquimod 5% cream for the treatment of actinic cheilitis: a 12-month follow-up study. (21916880)
2011
9
Actinic cheilitis: a case report and a review of the literature. (21228959)
2011
10
Actinic cheilitis among agricultural workers in Campinas, Brazil. (21485236)
2011
11
A case of metastatic squamous cell carcinoma arising from actinic cheilitis. (21738376)
2011
12
Actinic cheilitis: aesthetic and functional comparative evaluation of vermilionectomy using the classic and W-plasty techniques. (21437524)
2011
13
Actinic cheilitis: evolution to squamous cell carcinoma after carbon dioxide laser vaporization. A study of 43 cases. (19418331)
2010
14
Actinic cheilitis: a treatment review. (20964646)
2010
15
Diclofenac in hyaluronic acid gel: an alternative treatment for actinic cheilitis. (21085813)
2010
16
Morphology of collagen fibers and elastic system fibers in actinic cheilitis. (21187617)
2010
17
Treatment of actinic cheilitis with imiquimod 5% and a retractor on the lower lip: clinical and histological outcomes in 5 patients. (19836865)
2010
18
Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis. (20890667)
2010
19
Identification of novel fibroblast growth factor receptor 3 gene mutations in actinic cheilitis and squamous cell carcinoma of the lip. (19327639)
2009
20
Cheilitis glandularis and actinic cheilitis: differential diagnoses - report of three unusual cases. (19281710)
2009
21
Density and migration of mast cells in lip squamous cell carcinoma and actinic cheilitis. (19224448)
2009
22
Actinic cheilitis treated with one cycle of 5-aminolaevulinic acid-based photodynamic therapy: report of 10 cases. (18489592)
2008
23
Recognition and treatment of actinic cheilitis. (18481555)
2008
24
Acute actinic cheilitis-like chemical irritant reaction following accidental contact with ethylene glycol-favorable response to topical 1% pimecrolimus cream: a case report. (18568894)
2008
25
p53 and MDM2 protein expression in actinic cheilitis. (19082401)
2008
26
Dermabrasion for actinic cheilitis. (18363728)
2008
27
Epithelial expression of p53, mdm-2 and p21 in normal lip and actinic cheilitis. (18234540)
2008
28
Signal transducer and activator of transcription-3 expression and activation is dysregulated in actinic cheilitis. (17640230)
2007
29
A new modality in the treatment of actinic cheilitis using the Er:YAG laser. (17506137)
2007
30
Aminolevulinic acid photodynamic therapy for actinic keratoses/actinic cheilitis/acne: vascular lasers. (17126739)
2007
31
Treatment of actinic cheilitis using photodynamic therapy with methyl aminolevulinate: report of three cases. (16188193)
2005
32
Laser-mediated photodynamic therapy of actinic cheilitis. (15552607)
2004
33
Topical 5% imiquimod for the therapy of actinic cheilitis. (12271290)
2002
34
Surgical management of actinic cheilitis. (11500638)
2001
35
Comparison of electrodessication with CO2 laser for the treatment of actinic cheilitis. (10759824)
2000
36
Actinic cheilitis. (9568209)
1998
37
Actinic cheilitis. A treatment review. (9107289)
1997
38
Actinic cheilitis: a premalignant condition. (9515418)
1997
39
Actinic cheilitis. (8308614)
1993
40
Carbon dioxide laser treatment for actinic cheilitis. (8336236)
1993
41
Actinic cheilitis granulomatosa. (1479115)
1992
42
Custom lip shield for chronic actinic cheilitis. (2051365)
1991
43
Actinic cheilitis. Treatment with the carbon dioxide laser. (2106386)
1990
44
Carbon dioxide laser vermilionectomy for chronic actinic cheilitis. (2487875)
1989
45
Actinic cheilitis. A prospective study comparing four treatment methods. (2736096)
1989
46
Laser vermilion ablation for actinic cheilitis. (4008733)
1985
47
Actinic cheilitis. Diagnosis, prevention, and treatment. (6983788)
1982
48
Histopathology of actinic cheilitis. (6077128)
1967
49
CHRONIC ACTINIC CHEILITIS AND CANCER OF THE LOWER LIP. (14154810)
1964
50
Labial heterotopia of the salivary glands with actinic cheilitis-a new syndrome]. (14379725)
1955

Variations for Actinic Cheilitis

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Expression for genes affiliated with Actinic Cheilitis

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Actinic Cheilitis

Search GEO for disease gene expression data for Actinic Cheilitis.

Pathways for genes affiliated with Actinic Cheilitis

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Sources:
50PathCards, 30KEGG, 55Reactome, 53QIAGEN
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Compounds for genes affiliated with Actinic Cheilitis

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Sources:
45Novoseek, 51PharmGKB, 29IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Actinic Cheilitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1tamoxifen45 51 29 1112.1CHKB, SERPINB5
2aspirin45 51 29 2411.8CHKB, SERPINB5
3nitric oxide45 24 1110.5CD274, CHKB, SERPINB5

GO Terms for genes affiliated with Actinic Cheilitis

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16Gene Ontology
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Cellular components related to Actinic Cheilitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098979.3CD274, PDCD1

Biological processes related to Actinic Cheilitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1immune responseGO:0069559.5CD274, CD1A
2T cell costimulationGO:0312959.0CD274, PDCD1

Products for genes affiliated with Actinic Cheilitis

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  • Antibodies
  • Proteins
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  • Antibodies

Sources for Actinic Cheilitis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet