MCID: ACT164
MIFTS: 32

Actinic Prurigo malady

Categories: Genetic diseases, Skin diseases, Rare diseases

Aliases & Classifications for Actinic Prurigo

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Sources:
51Orphanet, 65UMLS, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Actinic Prurigo:

Name: Actinic Prurigo 51 65
Hereditary Polymorphous Light Eruption of American Indians 51
Familial Polymorphous Light Eruption of American Indians 51
 
Hutchinson Summer Prurigo 51
Hydroa Aestivale 51
Hydroa Estivale 65

Characteristics:

Orphanet epidemiological data:

51
actinic prurigo:
Inheritance: Multigenic/multifactorial,Not applicable; Age of onset: Childhood

Classifications:

Orphanet: 51 
Rare skin diseases


External Ids:

Orphanet51 330061
ICD10 via Orphanet28 L56.4
UMLS65 C0406217, C3247203

Summaries for Actinic Prurigo

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Wikipedia:68 Actinic prurigo (also known as \"Familial polymorphous light eruption of American Indians,\"... more...

MalaCards based summary: Actinic Prurigo, also known as hereditary polymorphous light eruption of american indians, is related to porphyria and congenital porphyria, and has symptoms including juvenile spring eruption An important gene associated with Actinic Prurigo is TNF (Tumor Necrosis Factor), and among its related pathways are HTLV-I infection and Influenza A. Affiliated tissues include skin, breast and thyroid.

Related Diseases for Actinic Prurigo

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Diseases related to Actinic Prurigo via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 64)
idRelated DiseaseScoreTop Affiliating Genes
1porphyria10.3
2congenital porphyria10.3
3hypertrichosis10.1
4hydroa vacciniforme10.1
5cheilitis10.1
6congenital cataract-progressive muscular hypotonia-hearing loss-developmental delay syndrome10.0HLA-DRB1, TNF
7microsomia hemifacial radial defects10.0HLA-DRB1, TNF
8autoimmune polyglandular syndrome type 210.0HLA-DRB1, TNF
9best1 retinopathy10.0HLA-DRB1, TNF
10non-distal monosomy 10q10.0HLA-DRB1, TNF
11androgen insensitivity syndrome, mild10.0HLA-DRB1, TNF
12lujo hemorrhagic fever10.0HLA-DRB1, TNF
13drug-induced mental disorder10.0HLA-DRB1, TNF
14rhizomelic dysplasia patterson lowry type10.0HLA-DRB1, TNF
15collagenous colitis9.9HLA-DRB1, TNF
16hypercementosis9.9HLA-DRB1, TNF
17noonan-like/multiple giant cell lesion syndrome9.9HLA-DRB1, TNF
18lymphocytic choriomeningitis9.9HLA-DRB1, TNF
19moderately severe hemophilia a9.9HLA-DRB1, TNF
20cytoplasmic body myopathy9.9HLA-DRB1, TNF
21hemorrhagic proctocolitis9.9HLA-DRB1, TNF
22cryptosporidiosis9.9HLA-DRB1, TNF
23hepatoid adenocarcinoma9.9HLA-DRB1, TNF
24idiopathic spinal cord herniation9.9HLA-DRB1, TNF
25kernicterus due to isoimmunization9.9HLA-DRB1, TNF
26secretory diarrhea9.9HLA-DRB1, TNF
27hypopharynx cancer9.9HLA-DRB1, TNF
28byssinosis9.9HLA-DRB1, TNF
29cholera9.9HLA-DRB1, TNF
30blue color blindness9.9HLA-DRB1, TNF
31keratomalacia9.9HLA-DRB1, TNF
32lateral sclerosis9.9HLA-DRB1, TNF
33progressive relapsing multiple sclerosis9.9HLA-DRB1, TNF
34artery disease9.9HLA-DRB1, TNF
35inflammatory spondylopathy9.9HLA-DRB1, TNF
36rectal disease9.9HLA-DRB1, TNF
37b-cell lymphomas9.8
38cutaneous lupus erythematosus9.8
39lymphoma9.8
40urticaria9.8
41dermatitis9.8
42contact dermatitis9.8
43allergic contact dermatitis9.8
44conjunctivitis9.8
45lupus erythematosus9.8
46solar urticaria9.8
47pupil disease9.8HLA-DRB1, TNF
48lung lymphoma9.8HLA-DRB1, TNF
49limited scleroderma9.8HLA-DRB1, TNF
50inflammatory bowel disease 39.8HLA-DRB1, TNF

Graphical network of the top 20 diseases related to Actinic Prurigo:



Diseases related to actinic prurigo

Symptoms for Actinic Prurigo

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UMLS symptoms related to Actinic Prurigo:


juvenile spring eruption

Drugs & Therapeutics for Actinic Prurigo

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Actinic Prurigo

Genetic Tests for Actinic Prurigo

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Anatomical Context for Actinic Prurigo

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MalaCards organs/tissues related to Actinic Prurigo:

33
Skin, Breast, Thyroid, Temporal lobe, Neutrophil, Endothelial, T cells

Animal Models for Actinic Prurigo or affiliated genes

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Publications for Actinic Prurigo

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Articles related to Actinic Prurigo:

(show top 50)    (show all 93)
idTitleAuthorsYear
1
Characteristics of actinic prurigo in Scotland: 24 cases seen between 2001 -2015. (26847497)
2016
2
Actinic Prurigo Cheilitis: A Clinicopathologic Review of 75 Cases. (26981737)
2016
3
Actinic Prurigo in Singaporean Chinese: A Positive Association with HLA-DRB1*03:01. (26787110)
2016
4
Adult-onset actinic prurigo: report of 19 patients from Taiwan. (26538497)
2015
5
Inmunohistochemical detection of mastocytes in tissue from patients with actinic prurigo. (26644844)
2015
6
Allergic contact dermatitis to Parthenium hysterophorus mimicking actinic prurigo. (25566915)
2015
7
Actinic Prurigo. (26861426)
2015
8
Actinic prurigo of the lip: Two case reports. (25133153)
2014
9
Clinical characteristics of adult-onset actinic prurigo in Asians: a case series. (24177610)
2013
10
Chronic actinic prurigo presenting in an adopted child. (20199425)
2010
11
Case for diagnosis. Actinic prurigo. (21152806)
2010
12
Epidermal Langerhans cells in Actinic Prurigo: a comparison between lesional and non-lesional skin. (19335731)
2009
13
Epidermal Langerhans cells in actinic prurigo: a comparison between lesional and non-lesional skin. (19744180)
2009
14
Hypodontia in a patient with actinic prurigo: a case report. (19619430)
2009
15
Class I and class II major histocompatibility complex genes in Mexican patients with actinic prurigo. (17355228)
2007
16
Actinic prurigo deterioration due to degradation of DermaGard window film. (17553049)
2007
17
Actinic prurigo in an Albanian girl. (16445427)
2006
18
Successful thalidomide therapy for actinic prurigo in a European woman. (17081272)
2006
19
Actinic prurigo. (16101881)
2005
20
Evidence that thalidomide modifies the immune response of patients suffering from actinic prurigo. (15569010)
2004
21
Actinic prurigo: a retrospective analysis of 21 cases referred to an Australian photobiology clinic. (11982570)
2002
22
A candidate gene analysis of three related photosensitivity disorders: cutaneous lupus erythematosus, polymorphic light eruption and actinic prurigo. (11531784)
2001
23
Long-term thalidomide for actinic prurigo. (11903163)
2001
24
Effectors of inflammation in actinic prurigo. (11369907)
2001
25
Use of topical cyclosporin for conjunctival manifestations of actinic prurigo. (11124306)
2000
26
A case of actinic prurigo showing hypersensitivity of skin fibroblasts to ultraviolet A (UVA). (10721864)
2000
27
A case of actinic prurigo in Thailand. (10692819)
2000
28
The clinical features and management of actinic prurigo: a retrospective study. (10540941)
1999
29
An immunohistochemical study of UV-induced skin lesions in actinic prurigo. Resistance of langerhans cells to UV light. (9649710)
1998
30
Further evidence of the role of HLA-DR4 in the genetic susceptibility to actinic prurigo. (9204058)
1997
31
Actinic prurigo: limited effect of PUVA. (9217842)
1997
32
Managing PLE and actinic prurigo. (9156494)
1997
33
What is actinic prurigo in Britain? (9372521)
1997
34
Profile of cytokine mRNA expression in spontaneous and UV-induced skin lesions from actinic prurigo patients. (9209891)
1997
35
HLA-DR4 may determine expression of actinic prurigo in British patients. (8601742)
1996
36
Actinic prurigo: an update. (7657433)
1995
37
Actinic prurigo. (7607801)
1995
38
Actinic prurigo. The possible etiologic role of an amino acid in the diet. (8231981)
1993
39
Histopathology of actinic prurigo. (8214390)
1993
40
Actinic prurigo: clinical features and prognosis. (1583166)
1992
41
Actinic prurigo. (1587676)
1992
42
Treatment of actinic prurigo with intermittent short-course topical 0.05% clobetasol 17-propionate. A preliminary report. (2396838)
1990
43
Actinic prurigo among the Chimila Indians in Colombia: HLA studies. (2370330)
1990
44
Actinic prurigo at sea level in Colombia. (2722335)
1989
45
Augmentation of ultraviolet erythema by indomethacin in actinic prurigo: evidence of mechanism of photosensitivity. (3380896)
1988
46
Thalidomide in actinic prurigo. (6838772)
1983
47
Actinic prurigo. (6629604)
1983
48
Actinic prurigo, a variety of polymorphous light eruption. (7095955)
1982
49
Actinic prurigo (Hutchinson's summer prurigo). (603975)
1977
50
Photodermatitis in North American Indians: familial actinic prurigo. (5558222)
1971

Variations for Actinic Prurigo

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Expression for genes affiliated with Actinic Prurigo

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Search GEO for disease gene expression data for Actinic Prurigo.

Pathways for genes affiliated with Actinic Prurigo

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GO Terms for genes affiliated with Actinic Prurigo

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Biological processes related to Actinic Prurigo according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1immune responseGO:00069559.1HLA-DRB1, TNF

Sources for Actinic Prurigo

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet