BOIL
MCID: ACT055
MIFTS: 40

Actinomycosis (BOIL) malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Actinomycosis

Aliases & Descriptions for Actinomycosis:

Name: Actinomycosis 12 50 56 42 14 69
Keratoactinomycosis 50 69
Actinomycetoma 12 69
Canaliculitis 50 69
Boil 12 14
Madura Foot Due to Actinomadura 12
Anaerobic Actinomyces Infection 50
Actinomycotic Mycetoma of Foot 12
Actinomycotic Madura Foot 12
Actinomycotic Infection 12
Actinomycotic Mycetema 12
Actinomyces Israeli 50
Actinomycetes 50
Furuncle 69

Characteristics:

Orphanet epidemiological data:

56
actinomycosis
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 56  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:8478
ICD10 33 A42 A42.9 B47.1
ICD9CM 35 039 039.9
MeSH 42 D000196
NCIt 47 C34350
Orphanet 56 ORPHA457095
ICD10 via Orphanet 34 A42.8 A42.7 A42.0 more
UMLS 69 C0001261

Summaries for Actinomycosis

Disease Ontology : 12 A commensal bacterial infectious disease that results_in infection, which is characterized by contiguous spread, suppurative and granulomatous inflammation, and formation of multiple abscesses and sinus tracts that may discharge sulfur granules, has material basis in Actinomyces israelii, has material basis in Actinomyces gerencseriae, has material basis in Actinomyces naeslundii, has material basis in Actinomyces odontolyticus, has material basis in Actinomyces viscosus, has material basis in Actinomyces meyeri, has material basis in Propionibacterium propionicum, which require a break in the integrity of the mucous membranes and the presence of devitalized tissue to invade deeper body structures.

MalaCards based summary : Actinomycosis, also known as keratoactinomycosis, is related to lung disease and chronic canaliculitis. An important gene associated with Actinomycosis is CNTN5 (Contactin 5). The drugs Miconazole and Ciclopirox have been mentioned in the context of this disorder. Affiliated tissues include skin, colon and lung.

NIH Rare Diseases : 50 actinomycosis is a chronic bacterial infection that commonly affects the face and neck. it is usually caused by an anaerobic bacteria called actinomyces israelii. actinomyces are normal inhabitants of the mouth, gastrointestinal tract, and female genital tract, and do not cause an infection unless there is a break in the skin or mucosa. the infection usually occurs in the face and neck, but can sometimes occur in the chest, abdomen, pelvis, or other areas of the body. the infection is not contagious. last updated: 4/28/2011

Wikipedia : 71 Actinomycosis is a rare infectious bacterial disease caused by Actinomyces species. About 70% of... more...

Related Diseases for Actinomycosis

Diseases related to Actinomycosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 135)
id Related Disease Score Top Affiliating Genes
1 lung disease 27.5 C10orf90 CNTN5 CTTNBP2 IL4 PHF20 RDH11
2 chronic canaliculitis 12.0
3 acute canaliculitis 11.9
4 hidradenitis suppurativa 11.4
5 farmer's lung 11.2
6 mycetoma 11.1
7 bagassosis 11.1
8 carbuncle 11.1
9 olecranon bursitis 10.8
10 hordeolum 10.8
11 ventilation pneumonitis 10.8
12 mushroom workers' lung 10.8
13 cutaneous leishmaniasis 10.8
14 biotin deficiency 10.8
15 diarrhea 10.8
16 perichondritis of auricle 10.8
17 hepatitis 10.2
18 fallopian tube adenomatoid tumor 10.0 RERE SMUG1
19 esophagitis 10.0
20 mycobacterium chelonae 9.9
21 burns 9.9
22 lung cancer 9.9
23 osteomyelitis 9.9
24 tonsillitis 9.9
25 nocardiosis 9.9
26 tuberculosis 9.9
27 hydronephrosis 9.8
28 cervicitis 9.8
29 laryngitis 9.8
30 pancreatitis 9.8
31 ovarian cancer 9.8
32 appendicitis 9.8
33 lymphogranuloma venereum 9.8
34 cryptosporidiosis 9.8
35 egg allergy 9.8
36 impetigo 9.8
37 bullous pemphigoid 9.8
38 nasopharyngitis 9.7
39 thyroiditis 9.7
40 dry eye syndrome 9.7
41 plasmacytoma 9.7
42 conjunctivitis 9.7
43 dacryocystitis 9.7
44 mycobacterium fortuitum 9.7
45 pyogenic granuloma 9.7
46 echinococcosis 9.7
47 bronchiectasis 9.7
48 sinusitis 9.7
49 pulmonary aspergilloma 9.7
50 thrombosis 9.7

Graphical network of the top 20 diseases related to Actinomycosis:



Diseases related to Actinomycosis

Symptoms & Phenotypes for Actinomycosis

Drugs & Therapeutics for Actinomycosis

Drugs for Actinomycosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
2
Ciclopirox Approved, Investigational Phase 4 29342-05-0 2749
3 Anti-Infective Agents Phase 4,Phase 3,Phase 1
4 Antifungal Agents Phase 4
5
Triclosan Approved Phase 3 3380-34-5 5564
6 Fluorides Phase 3
7
Tin Phase 3 7440-31-5
8 Tin Fluorides Phase 3
9 Hypolipidemic Agents Phase 3
10 Protective Agents Phase 3
11 Anti-Infective Agents, Local Phase 3,Phase 1
12 Lipid Regulating Agents Phase 3
13 Antimetabolites Phase 3
14 Cariostatic Agents Phase 3
15 Alkylating Agents Phase 3
16 Mitomycins Phase 3
17 Adjuvants, Immunologic Phase 3
18 Nucleic Acid Synthesis Inhibitors Phase 3
19 Vaccines Phase 3
20 Anti-Bacterial Agents Phase 3
21 Antibiotics, Antitubercular Phase 3
22 BCG Vaccine Phase 3
23
Chlorhexidine Approved, Vet_approved Phase 1,Early Phase 1 55-56-1 9552079 2713
24 Chlorhexidine gluconate Phase 1,Early Phase 1
25 Dermatologic Agents Phase 1
26 Disinfectants Phase 1
27
Menthol Approved Early Phase 1 2216-51-5 16666
28 Pharmaceutical Solutions Early Phase 1

Interventional clinical trials:


id Name Status NCT ID Phase
1 Safety Study of Ciclopirox Olamine Cream for Dermatomycoses in Children Terminated NCT01646580 Phase 4
2 Investigate Oral Bacteria in Adult Population Completed NCT00762177 Phase 3
3 Adding Mitomycin C to Bacillus of Calmette-Guerin (BCG) as Adjuvant Intravesical Therapy for High-risk, Non-Muscle-invasive Bladder Cancer Recruiting NCT02948543 Phase 3
4 Chlorhexidine Gel Therapy for Cariogenic Oral Microflora Completed NCT01036412 Phase 1
5 Oral Hygiene Intervention Pilot Study Active, not recruiting NCT02668809 Early Phase 1

Search NIH Clinical Center for Actinomycosis

Cochrane evidence based reviews: actinomycosis

Genetic Tests for Actinomycosis

Anatomical Context for Actinomycosis

MalaCards organs/tissues related to Actinomycosis:

39
Skin, Colon, Lung, Bone, Liver, Breast, Tonsil

Publications for Actinomycosis

Articles related to Actinomycosis:

(show top 50) (show all 629)
id Title Authors Year
1
Treatment of cutaneous actinomycosis with amoxicillin/clavulanic acid. ( 27151779 )
2016
2
Primary hepatic actinomycosis mimicking liver tumour. ( 27080813 )
2016
3
Pulmonary actinomycosis: a rare case diagnosed on bronchoalveolar lavage cytology. ( 28028884 )
2016
4
Abdominal actinomycosis presenting as appendicitis: two case reports and review. ( 27147718 )
2016
5
Primary actinomycosis of breast-A diagnosis on cytology. ( 27238823 )
2016
6
PELVIC ACTINOMYCOSIS MIMICKING A LOCALLY ADVANCED PELVIC MALIGNANCY--CASE REPORT. ( 27483724 )
2016
7
Actinomycosis Mimicking Tolosa-Hunt Syndrome in a 6-Year-Old Boy: Case Report. ( 27070954 )
2016
8
Primary Cutaneous Actinomycosis along with the Surgical Scar on the Hand. ( 27957360 )
2016
9
Primary cutaneous actinomycosis of scrotal skin: A rare entity often misdiagnosed. ( 27166055 )
2016
10
Actinomycosis Associated with Foreign Body Simulating Lung Cancer. ( 27816277 )
2016
11
Abdominal Actinomycosis in Children: A Case Report and Literature Review. ( 27870811 )
2016
12
Male Breast Abscess Secondary to Actinomycosis: A Case Report. ( 27190917 )
2016
13
Clinical features of actinomycosis: A retrospective, multicenter study of 28 cases of miscellaneous presentations. ( 27311002 )
2016
14
Pulmonary actinomycosis presenting as post-obstructive pneumonia. ( 27085876 )
2016
15
IMAGES IN CLINICAL MEDICINE. Cutaneous Actinomycosis. ( 27144852 )
2016
16
Empyema necessitans caused by actinomycosis: A case report. ( 27180228 )
2016
17
Cytopathology of Hepatobiliary-Related Actinomycosis. ( 27199159 )
2016
18
Primary Hepatic Actinomycosis Mimicking Hepatic Malignancy with Metastatic Lymph Nodes by F-18 FDG PET/CT. ( 26941867 )
2016
19
Overlapping lung parenchymal and bronchial lesion and hilar lymphadenopathy in pulmonary actinomycosis mimicking lung cancer. ( 27353181 )
2016
20
Actinomycosis of Finger: Case Report and Review of the Literature. ( 27656447 )
2016
21
Primary actinomycosis of vulva with inguinal lymphadenopathy. ( 27730039 )
2016
22
Actinomycosis mimicking an ovarian malignancy: Case report and literature review. ( 27751439 )
2016
23
Actinomycosis arising from the nasal cavity, with rare fatal progression. ( 26860115 )
2016
24
Actinomyces meyeri, a Common Agent of Actinomycosis. ( 27432035 )
2016
25
Actinomycosis resembling liver tumor with multiple metastasis. ( 26948481 )
2016
26
Actinomycosis after allogeneic hematopoietic stem cell transplantation despite penicillin prophylaxis. ( 27203624 )
2016
27
Endobronchial actinomycosis secondary to foreign body aspiration. ( 27744537 )
2016
28
Actinomycosis presenting as recurrent hepatic abscess. ( 27593605 )
2016
29
A case of ileocecal actinomycosis treated by preoperative antibiotic treatment to reduce mass size followed by surgical resection. ( 27151478 )
2016
30
A Case of Recalcitrant Actinomycosis Unresponsive to Antibiotic Therapy. ( 27832223 )
2016
31
The treatment of actinomycosis mimicking a retained root tip: a confusing case. ( 27595087 )
2016
32
Primary cutaneous actinomycosis over right gluteal region. ( 27294068 )
2016
33
Cervical vertebral actinomycosis mimicking malignancy in a paediatric patient. ( 27033296 )
2016
34
Pulmonary actinomycosis masquerading as lung cancer: Case letter. ( 27578949 )
2016
35
Actinomycosis of the abdominal wall after cholecystectomy: transferral theory. ( 27966440 )
2016
36
Thoracic Actinomycosis: A Rare Occurrence. ( 27103971 )
2016
37
Successful treatment of pelvic actinomycosis using transgluteal drainage: A case report. ( 26919913 )
2016
38
Unusual clinical presentation of actinomycosis mimicking mucocele. ( 25903033 )
2015
39
Complicated actinomycosis of the temporal bone: A historical case report. ( 25825360 )
2015
40
Pelvic Actinomycosis Associated with an Intrauterine Contraceptive Device Demonstrated on F-18 FDG PET/CT. ( 26854159 )
2015
41
Actinomycosis associated with a retained pencil core for a period of 13 years. ( 25640697 )
2015
42
Dysphagia Caused by Esophageal Actinomycosis. ( 25625626 )
2015
43
Actinomycosis: a frequently forgotten disease. ( 25865197 )
2015
44
Actinomycosis of submandibular gland: An unusual presentation of a rare entity. ( 26097319 )
2015
45
Abdominal actinomycosis after laparoscopic cholecystectomy: an uncommon presentation of an uncommon problem. ( 25988074 )
2015
46
Case 219: Pelvic Actinomycosis Mimicking Malignant Tumor. ( 26101924 )
2015
47
Xanthogranulomatous gastritis associated with actinomycosis: report of a case presenting as a large submucosal mass. ( 25755811 )
2015
48
Primary gastric actinomycosis: report of a case diagnosed in a gastroscopic biopsy. ( 25774092 )
2015
49
Pilonidal Abscess Associated With Primary Actinomycosis. ( 26817020 )
2015
50
A suspicious pancreatic mass in chronic pancreatitis: pancreatic actinomycosis. ( 25705533 )
2015

Variations for Actinomycosis

Expression for Actinomycosis

Search GEO for disease gene expression data for Actinomycosis.

Pathways for Actinomycosis

GO Terms for Actinomycosis

Sources for Actinomycosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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