MCID: ACT046
MIFTS: 14

Acute Apical Periodontitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Acute Apical Periodontitis

MalaCards integrated aliases for Acute Apical Periodontitis:

Name: Acute Apical Periodontitis 12 14
Acute Apical Periodontitis of Pulpal Origin 12 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11693
ICD10 32 K04.4
ICD9CM 34 522.4
UMLS 69 C0155934

Summaries for Acute Apical Periodontitis

MalaCards based summary : Acute Apical Periodontitis, also known as acute apical periodontitis of pulpal origin, is related to periodontitis and episodic pain syndrome, familial, 1. An important gene associated with Acute Apical Periodontitis is TSPAN7 (Tetraspanin 7). The drugs Clindamycin and Amoxicillin have been mentioned in the context of this disorder.

Related Diseases for Acute Apical Periodontitis

Diseases in the Acute Apical Periodontitis family:

Chronic Apical Periodontitis

Diseases related to Acute Apical Periodontitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 periodontitis 10.3
2 episodic pain syndrome, familial, 1 10.0
3 pulpitis 9.8

Comorbidity relations with Acute Apical Periodontitis via Phenotypic Disease Network (PDN):


Dental Caries Heart Disease
Ischemic Heart Disease

Symptoms & Phenotypes for Acute Apical Periodontitis

Drugs & Therapeutics for Acute Apical Periodontitis

Drugs for Acute Apical Periodontitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clindamycin Approved, Vet_approved Phase 2, Phase 3 18323-44-9 29029
2
Amoxicillin Approved, Vet_approved Phase 2, Phase 3,Not Applicable 26787-78-0 33613 2171
3 Anti-Bacterial Agents Phase 2, Phase 3,Phase 3,Not Applicable
4 Anti-Infective Agents Phase 2, Phase 3,Phase 3,Not Applicable
5 Clindamycin palmitate Phase 2, Phase 3
6 Clindamycin phosphate Phase 2, Phase 3
7 Amoxicillin-Potassium Clavulanate Combination Phase 2, Phase 3,Not Applicable
8 beta-Lactamase Inhibitors Phase 2, Phase 3,Not Applicable
9 Clavulanic Acid Phase 2, Phase 3,Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Preoperative Clindamycin on Postoperative Endodontic Pain Not yet recruiting NCT03033472 Phase 2, Phase 3 600 mg Clindamycin orally;Oral Placebo
2 Effect of Preoperative Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain Not yet recruiting NCT03033147 Phase 2, Phase 3 Amoxicillin/Clavulanate Potassium 875 mg-125 mg oral tablet;Oral placebo
3 Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain Not yet recruiting NCT03007342 Not Applicable Amoxicillin/Clavulanate Potassium 875 mg-125 mg oral tablet;Placebo

Search NIH Clinical Center for Acute Apical Periodontitis

Genetic Tests for Acute Apical Periodontitis

Anatomical Context for Acute Apical Periodontitis

Publications for Acute Apical Periodontitis

Articles related to Acute Apical Periodontitis:

# Title Authors Year
1
Acute apical periodontitis and vertical root fracture of the same tooth: a case report. ( 23748460 )
2013
2
Preoperative pain and medications used in emergency patients with irreversible acute pulpitis or acute apical periodontitis: a prospective comparative study. ( 18018991 )
2007
3
Clinical practice guideline on emergency management of acute apical periodontitis (AAP) in adults. ( 15238966 )
2004
4
Clinical practice guidelines on emergency management of acute apical periodontitis and acute apical abscess. Evidence-based Dentistry 2004;5:7-11. ( 15448658 )
2004
5
Emergency management of acute apical periodontitis in the permanent dentition: a systematic review of the literature. ( 12622880 )
2003
6
Talon cusp causing occlusal trauma and acute apical periodontitis: report of a case. ( 12656857 )
2003
7
A comparison of ketorolac tromethamine and acetaminophen codeine in the management of acute apical periodontitis. ( 10425951 )
1999
8
Acute apical periodontitis: incidence of post-operative pain using two different root canal dressings. ( 9823137 )
1998
9
Corticosteroid use in acute apical periodontitis: a review with clinical implications. ( 3078589 )
1988
10
Remission of pain of acute apical periodontitis after blockage of apex with filings: case report. ( 1062494 )
1976

Variations for Acute Apical Periodontitis

Expression for Acute Apical Periodontitis

Search GEO for disease gene expression data for Acute Apical Periodontitis.

Pathways for Acute Apical Periodontitis

GO Terms for Acute Apical Periodontitis

Sources for Acute Apical Periodontitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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