MCID: ACT028
MIFTS: 25

Acute Closed-Angle Glaucoma

Categories: Eye diseases

Aliases & Classifications for Acute Closed-Angle Glaucoma

MalaCards integrated aliases for Acute Closed-Angle Glaucoma:

Name: Acute Closed-Angle Glaucoma 12 14
Acute Angle-Closure Glaucoma 12 69

Classifications:



External Ids:

Disease Ontology 12 DOID:13862
ICD10 32 H40.21
ICD9CM 34 365.22
SNOMED-CT 64 30041005
UMLS 69 C0154946

Summaries for Acute Closed-Angle Glaucoma

MalaCards based summary : Acute Closed-Angle Glaucoma, also known as acute angle-closure glaucoma, is related to neuropathy and nonarteritic anterior ischemic optic neuropathy. An important gene associated with Acute Closed-Angle Glaucoma is MFRP (Membrane Frizzled-Related Protein). The drugs Topiramate and Anticonvulsants have been mentioned in the context of this disorder. Affiliated tissues include eye and lung.

Related Diseases for Acute Closed-Angle Glaucoma

Diseases in the Acute Closed-Angle Glaucoma family:

Chronic Closed-Angle Glaucoma

Diseases related to Acute Closed-Angle Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
# Related Disease Score Top Affiliating Genes
1 neuropathy 10.2
2 nonarteritic anterior ischemic optic neuropathy 10.1
3 ischemic optic neuropathy 10.1
4 hypopyon 10.1
5 vogt-koyanagi-harada disease 10.1
6 miller fisher syndrome 10.1
7 amblyopia 10.1 MFRP OPTN
8 primary angle-closure glaucoma 10.1 MFRP OPTN
9 chronic closed-angle glaucoma 10.0 CTSA OPTN
10 optic nerve disease 10.0 MFRP OPTN
11 sturge-weber syndrome 10.0
12 pseudoxanthoma elasticum 10.0
13 coats disease 10.0
14 retinal ischemia 10.0
15 weill-marchesani syndrome 10.0
16 renal hypertension 10.0
17 lens subluxation 10.0
18 myopia 10.0
19 ischemic neuropathy 10.0
20 scleritis 10.0
21 posterior scleritis 10.0
22 ischemia 10.0
23 retinitis 10.0
24 blepharospasm 10.0
25 cocaine abuse 10.0
26 weber syndrome 10.0
27 phacogenic glaucoma 9.9 OPTN PEX19
28 arteriovenous fistula 9.9
29 intracranial aneurysm 9.9
30 choroiditis 9.9
31 aneurysm 9.9
32 iris disease 9.9 OPTN PEX19
33 coloboma of macula 9.9 MFRP OPTN
34 lens disease 9.9 OPTN PEX19
35 corneal endothelial dystrophy 9.9 CTSA OPTN
36 nervous system disease 9.7 MFRP OPTN

Comorbidity relations with Acute Closed-Angle Glaucoma via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Acute Closed-Angle Glaucoma:



Diseases related to Acute Closed-Angle Glaucoma

Symptoms & Phenotypes for Acute Closed-Angle Glaucoma

Drugs & Therapeutics for Acute Closed-Angle Glaucoma

Drugs for Acute Closed-Angle Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Topiramate Approved Phase 4 97240-79-4 5284627
2 Anticonvulsants Phase 4
3 Anti-Obesity Agents Phase 4
4 Neuroprotective Agents Phase 4
5 Protective Agents Phase 4
6
Epinephrine Approved, Vet_approved Phase 2, Phase 3 51-43-4 5816
7 Racepinephrine Approved Phase 2, Phase 3 329-65-7
8 Adrenergic Agents Phase 2, Phase 3
9 Adrenergic Agonists Phase 2, Phase 3
10 Adrenergic alpha-Agonists Phase 2, Phase 3
11 Adrenergic beta-Agonists Phase 2, Phase 3
12 Anti-Asthmatic Agents Phase 2, Phase 3
13 Autonomic Agents Phase 2, Phase 3
14 Bronchodilator Agents Phase 2, Phase 3
15 Epinephryl borate Phase 2, Phase 3
16 Mydriatics Phase 2, Phase 3
17 Neurotransmitter Agents Phase 2, Phase 3
18 Peripheral Nervous System Agents Phase 2, Phase 3
19 Respiratory System Agents Phase 2, Phase 3
20 Vasoconstrictor Agents Phase 2, Phase 3
21
Mannitol Approved, Investigational 69-65-8 6251 453
22
Acetazolamide Approved, Vet_approved 59-66-5 1986
23 diuretics
24 Natriuretic Agents
25 Carbonic Anhydrase Inhibitors

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Relationship Between Topiramate Use and Ocular Angle Status Unknown status NCT00153699 Phase 4 Topiramate
2 Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies Recruiting NCT03126968 Phase 2, Phase 3 Topical epinephrine;Placebos
3 Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG) Completed NCT01965106 Phase 2 QPI-1007 Injection;(including placebo)
4 Angle Closure (Glaucoma) in Caucasians Unknown status NCT02054403
5 Comparison of Anterior Chamber Paracentesis and Conventional Mannitol Infusion in Patients With Primary Acute Angle-closure Glaucoma Completed NCT01266343
6 Immediate Anterior Chamber Paracentesis With A 30-Gauge Needle for Acute Primary Angle - Closure Completed NCT01923454 Acetazolamide
7 Sequential Laser Iridotomy Using Argon and Q-Switched 532 nm Frequency Doubled Neodymium Yag Laser: A Pilot Study Completed NCT00452998

Search NIH Clinical Center for Acute Closed-Angle Glaucoma

Genetic Tests for Acute Closed-Angle Glaucoma

Anatomical Context for Acute Closed-Angle Glaucoma

MalaCards organs/tissues related to Acute Closed-Angle Glaucoma:

38
Eye, Lung

Publications for Acute Closed-Angle Glaucoma

Articles related to Acute Closed-Angle Glaucoma:

(show all 41)
# Title Authors Year
1
Acute Angle-closure Glaucoma as a First Presentation of Coats' Disease: A Case Report. ( 29176335 )
2018
2
Miller Fisher syndrome with acute angle-closure glaucoma as the first manifestation: A case report. ( 29390338 )
2017
3
Acute Angle Closure Glaucoma in a Patient with Pseudoxanthoma Elasticum. ( 28914006 )
2017
4
Association of Selective Serotonin Reuptake Inhibitor Use and Acute Angle-Closure Glaucoma. ( 27135704 )
2016
5
Bilateral acute closed angle glaucoma associated with the discontinuation of escitalopram: a case report. ( 27660499 )
2016
6
Refractory acute angle-closure glaucoma with retinal ischemia: January consultation #1. ( 26948794 )
2016
7
Acute angle-closure glaucoma in a highly myopic patient secondary to Weill-Marchesani syndrome: histopathologic lens features. ( 26966104 )
2016
8
Bilateral acute angle closure glaucoma following a snake bite: Are we missing it? ( 26955216 )
2016
9
Retraction: Bilateral acute angle closure glaucoma following a snake bite: Are we missing it? ( 27076740 )
2016
10
Oblique Flashlight Test: Lighting Up Acute Angle-Closure Glaucoma. ( 27173500 )
2016
11
Unilateral Acute Closed-Angle Glaucoma After Elective Lumbar Surgery Reveals Multiple Intracranial Aneurysms. A Case Report and Discussion on Workup of Differential Diagnoses. ( 25959248 )
2015
12
Acute Angle-Closure Glaucoma in a Patient With Miller Fisher Syndrome Without Pupillary Dysfunction. ( 25393040 )
2014
13
Oseltamivir (Tamiflu)-induced bilateral acute angle closure glaucoma and transient myopia. ( 23571265 )
2013
14
Bilateral nonarteritic anterior ischemic neuropathy following acute angle-closure glaucoma in a patient with iridoschisis: case report. ( 21670912 )
2011
15
Vogt-Koyanagi-Harada disease presenting as acute angle closure glaucoma at onset. ( 22452682 )
2011
16
Nonarteritic anterior ischemic optic neuropathy in a patient with primary acute angle-closure glaucoma. ( 19020646 )
2008
17
Anterior segment optical coherence tomography findings of acute angle-closure glaucoma in Vogt-Koyanagi-Harada disease. ( 18661276 )
2008
18
Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma. ( 17608625 )
2008
19
The association of membrane frizzled-related protein (MFRP) gene with acute angle-closure glaucoma--a pilot study. ( 18781223 )
2008
20
Spontaneous, late, in-the-bag intraocular lens subluxation in a patient with a previous acute angle-closure glaucoma attack. ( 15313313 )
2004
21
A case of acute angle-closure glaucoma secondary to posterior scleritis in patient with Sturge-Weber syndrome. ( 11853718 )
2002
22
Anterior ischemic optic neuropathy following acute angle-closure glaucoma. ( 11483097 )
2001
23
Primary care diagnosis of acute closed-angle glaucoma. A case report. ( 9460008 )
1997
24
Acute angle-closure glaucoma associated with intranasal cocaine abuse. ( 8794717 )
1996
25
Hypopyon--an unusual sign in acute angle-closure glaucoma. ( 8262710 )
1993
26
Acute closed angle glaucoma and sunshine. ( 1795149 )
1991
27
Renal hypertension presenting as acute angle closure glaucoma. ( 2043062 )
1991
28
Acute closed-angle glaucoma and Nd-YAG laser iridotomy. ( 2393642 )
1990
29
Acute angle-closure glaucoma following botulinum toxin injection for blepharospasm. ( 2354140 )
1990
30
Acute closed-angle glaucoma after arteriovenous fistulas. ( 2913810 )
1989
31
Acute closed-angle glaucoma complicating hemorrhagic choroidal detachment associated with parenteral thrombolytic agents. ( 3195662 )
1988
32
Psychophysiological stress, elevated intraocular pressure, and acute closed-angle glaucoma. ( 3425684 )
1987
33
Hypopyon keratouveitis in acute angle-closure glaucoma. ( 3661656 )
1987
34
Diurnal variation in onset of acute closed angle glaucoma. ( 3084019 )
1986
35
Acute closed-angle glaucoma: an investigation into the effect of delay in treatment. ( 526462 )
1979
36
Management of acute closed-angle glaucoma with miotics and timolol. ( 526463 )
1979
37
Acute closed-angle glaucoma, a complication of blepharoplasty: report of a case. ( 4817143 )
1974
38
Life events and the onset of acute closed-angle glaucoma. ( 5071431 )
1972
39
THE FELLOW EYE: ANALYSIS OF 50 CASES OF ACUTE CLOSED-ANGLE GLAUCOMA. ( 14192687 )
1964
40
SELF-LIMITING ACUTE CLOSED-ANGLE GLAUCOMA WITH SEGMENTAL IRIS SHORTENING. ( 14189725 )
1963
41
The fellow eye in acute closed-angle glaucoma. ( 13413134 )
1957

Variations for Acute Closed-Angle Glaucoma

Expression for Acute Closed-Angle Glaucoma

Search GEO for disease gene expression data for Acute Closed-Angle Glaucoma.

Pathways for Acute Closed-Angle Glaucoma

GO Terms for Acute Closed-Angle Glaucoma

Sources for Acute Closed-Angle Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....