MCID: ACT004
MIFTS: 44

Acute Diarrhea malady

Genetic diseases, Gastrointestinal diseases, Rare diseases categories
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Summaries for Acute Diarrhea

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Disease Ontology:8 A diarrhea that is of rapid onset and course characterized by frequent loose or liquid bowel movements. acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide.

MalaCards based summary: Acute Diarrhea is related to diarrhea and hepatitis. An important gene associated with Acute Diarrhea is PITX1 (paired-like homeodomain 1), and among its related pathways are Selected targets of ESR1 and Selected targets of C EBPalpha. The compounds toluene diisocyanate and heroin have been mentioned in the context of this disorder. Affiliated tissues include small intestine, breast and t cells, and related mouse phenotype homeostasis/metabolism.

Wikipedia:65 Gastroenteritis or infectious diarrhea is a medical condition from inflammation (\"-itis\") of the... more...

Aliases & Classifications for Acute Diarrhea

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Acute Diarrhea, Aliases & Descriptions:

Name: Acute Diarrhea 8 10 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Gastrointestinal diseases


External Ids:

Disease Ontology8 DOID:0050140

Related Diseases for Acute Diarrhea

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Diseases in the Chronic Diarrhea Due to Guanylate Cyclase 2c Overactivity family:

Inflammatory Diarrhea acute diarrhea
Diarrhea Diarrhea 7

Diseases related to Acute Diarrhea via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 101)
idRelated DiseaseScoreTop Affiliating Genes
1diarrhea32.2LTF, ALB
2hepatitis30.3ALB, LTF
3primary biliary cirrhosis30.0ALB, LTF
4blindness10.6
5cholera10.4
6cholangitis10.4ALB
7eosinophilic gastroenteritis10.3IGHE
8strongyloidiasis10.3IGHE
9bronchiolitis10.2IGHE
10cryptosporidiosis10.2
11membranous glomerulonephritis10.2ALB, MME
12kernicterus10.2ALB, G6PD
13malaria10.2G6PD, ALB
14bilirubin metabolic disorder10.2G6PD, ALB
15iron deficiency anemia10.1LTF, G6PD
16acute kidney failure10.1ALB, G6PD
17mastitis10.1LTF, ALB
18amyloid tumor10.1MME, LTF
19shigellosis10.1
20metabolic acidosis10.1
21gastroenteritis10.1
22influenza10.1
23agammaglobulinemia, x-linked 110.1
24amyloidosis10.1ALB, MME
25asthma10.1IGHE, MME
26ulcerative colitis10.1LTF, ALB
27crohn's disease10.1LTF, ALB
28angioedema10.0IGHE, MME
29essential hypertension10.0ALB, MME
30respiratory failure10.0G6PD, IGHE
31vasculitis10.0LTF, ALB
32rhinitis10.0IGHE, ALB
33primary hyperoxaluria10.0ALB, MME, G6PD
34otitis media10.0LTF, IGHE
35deficiency anemia10.0G6PD, MME, ALB
36viral infectious disease10.0PITX1, G6PD, MME
37bronchitis10.0LTF, IGHE
38autoimmune hepatitis10.0
39cerebral palsy10.0
40hiv-110.0
41bloom syndrome10.0
42dracunculiasis10.0
43rift valley fever10.0
44acute urate nephropathy10.0
45kawasaki disease10.0
46congenital toxoplasmosis10.0
47typhoid fever10.0
48lassa fever10.0
49hypoglycemia10.0
50yellow fever10.0

Graphical network of the top 20 diseases related to Acute Diarrhea:



Diseases related to acute diarrhea

Symptoms for Acute Diarrhea

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Drugs & Therapeutics for Acute Diarrhea

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Drug clinical trials:

Search ClinicalTrials for Acute Diarrhea

Search NIH Clinical Center for Acute Diarrhea

Genetic Tests for Acute Diarrhea

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Anatomical Context for Acute Diarrhea

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MalaCards organs/tissues related to Acute Diarrhea:

32
Small intestine, Breast, T cells, Appendix

Animal Models for Acute Diarrhea or affiliated genes

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MGI Mouse Phenotypes related to Acute Diarrhea:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.9LTF, ALB, MME, G6PD, IGHE

Publications for Acute Diarrhea

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Articles related to Acute Diarrhea:

(show top 50)    (show all 512)
idTitleAuthorsYear
1
Effectiveness of multifaceted interventions on rational use of antibiotics for patients with upper respiratory tract infections and acute diarrhea. (24772576)
2014
2
Thymic stromal lymphopoietin-mediated epicutaneous inflammation promotes acute diarrhea and anaphylaxis. (25365222)
2014
3
Therapeutic zinc and copper supplementation in acute diarrhea does not influence short-term morbidity and growth: double-blind randomized controlled trial. (22926212)
2013
4
Enteroaggregative Escherichia coli and acute diarrhea in children: a meta-analysis of South Asian populations. (23179250)
2013
5
Potential impact of influenza A/H1N1 pandemic and hand-gels on acute diarrhea epidemic in France. (24124479)
2013
6
Acute diarrhea in West African children: diverse enteric viruses and a novel parvovirus genus. (22855485)
2012
7
Acute diarrhea among military recruits. (23214210)
2012
8
Molecular characterization of Salmonella strains in individuals with acute diarrhea syndrome in the State of Sucre, Venezuela. (22760131)
2012
9
Acute diarrhea in hospitalized children of the municipality of Juiz de Fora, MG, Brazil: prevalence and risk factors associated with disease severity. (23329220)
2012
10
A prospective study of acute diarrhea in a cohort of United States military personnel on deployment to the Multinational Force and Observers, Sinai, Egypt. (21212203)
2011
11
Seasonal variation of enteropathogens in infants and preschoolers with acute diarrhea in western Mexico. (20706147)
2010
12
Clinical trial on the efficacy of a new symbiotic formulation, Flortec, in patients with acute diarrhea: a multicenter, randomized study in primary care. (20616746)
2010
13
Zinc and copper supplementation in acute diarrhea in children: a double-blind randomized controlled trial. (19416499)
2009
14
Acute diarrhea in hospitalized horses. (19580946)
2009
15
Advances in defining etiology and new therapeutic approaches in acute diarrhea. (17825422)
2007
16
Acute diarrhea in the adult horse: case example and review. (16627106)
2006
17
Cytotoxicity and antimicrobial susceptibility of Clostridium difficile isolated from hospitalized children with acute diarrhea. (16701515)
2004
18
Epidemiologic and clinical characteristics of acute diarrhea with emphasis on Entamoeba histolytica infections in preschool children in an urban slum of Dhaka, Bangladesh. (14640500)
2003
19
Detection, subgroup specificity, and genotype diversity of rotavirus strains in children with acute diarrhea in Paraguay. (11980947)
2002
20
A double blind, randomized, placebo-controlled study of SP-303 (Provir) in the symptomatic treatment of acute diarrhea among travelers to Jamaica and Mexico. (12385443)
2002
21
Spectrum of vibrio species associated with acute diarrhea in North Jakarta, Indonesia. (12088614)
2002
22
Surveillance of bacterial pathogens associated with acute diarrhea in Lima, Peru. (10737846)
2000
23
Can malabsorbed carbohydrates be useful in the treatment of acute diarrhea? (11144433)
2000
24
Molecular Epidemiology of Group A Rotavirus Causing Acute Diarrhea in Infants and Young Children in Rio de Janeiro, Brazil, 1997-1998. (11096435)
1999
25
Acute diarrhea: a practical review. (10378626)
1999
26
Use of undiluted whole cow's milk is effective for the routine treatment of children with acute diarrhea and severe dehydration. (9814379)
1998
27
Dietary management of acute diarrhea with local foods in a Guatemalan rural community. (9401505)
1997
28
Evaluation of a simplified HEp-2 cell adherence assay for Escherichia coli isolated from south Indian children with acute diarrhea and controls. (7559981)
1995
29
Composition and preliminary evaluation of a hydrolyzed rice-based oral rehydration solution for the treatment of acute diarrhea in children. (8586781)
1995
30
New developments in acute diarrhea. (8055704)
1994
31
Two-year study of endemic enteric pathogens associated with acute diarrhea in New Caledonia. (8077399)
1994
32
Control randomized study of rehydration/rehydration with dioctahedral smectite in ambulatory Thai infants with acute diarrhea. (7825006)
1994
33
Loperamide oxide in the treatment of acute diarrhea in adults. (7697694)
1994
34
Earth, wind, and fiber: is there a drug to treat acute diarrhea? (7815252)
1994
35
The management of acute diarrhea in children: oral rehydration, maintenance, and nutritional therapy. Centers for Disease Control and Prevention. (1435668)
1992
36
Effect of diosmectite on intestinal permeability changes in acute diarrhea: a double-blind placebo-controlled trial. (1517944)
1992
37
Comparison of glucose/electrolyte and maltodextrin/glycine/glycyl-glycine/electrolyte oral rehydration solutions in acute diarrhea in children. (1779314)
1991
38
Enterotoxins and adhesins of enterotoxigenic Escherichia coli: are they risk factors for acute diarrhea in the community? (1973696)
1990
39
Acute diarrhea in children. (2664748)
1989
40
Enteropathogenic serotypes of E. coli in acute diarrhea in Ajmer. (3068136)
1988
41
Detection of enterotoxigenic strains of Escherichia coli in children with acute diarrhea. (3334593)
1987
42
A two-year longitudinal study on the etiology of acute diarrhea in young children in Northern Italy. (2983179)
1985
43
The evaluation and management of acute diarrhea. (6730484)
1984
44
Etiological agents responsible for acute diarrhea in children in an urban community in Burma. (6226849)
1983
45
Nonenteric sources of rotavirus in acute diarrhea. (6273477)
1981
46
Acute diarrhea on an Apache Indian reservation. (4594476)
1974
47
The participation of lactic acid in disturbances of the acid-base balance in acute diarrhea in infants. (5370557)
1969
48
Hypoglycemia in neonatal calves associated with acute diarrhea. (5655836)
1968
49
Spectrum of acute diarrhea in a general hospital. 4. "Antibiotic bowel" and pseudomembranous enterocolitis. (5827657)
1965
50
Spectrum of acute diarrhea in general hospitals. 5. Conclusion. (5827658)
1965

Variations for Acute Diarrhea

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Expression for genes affiliated with Acute Diarrhea

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Expression patterns in normal tissues for genes affiliated with Acute Diarrhea

Search GEO for disease gene expression data for Acute Diarrhea.

Pathways for genes affiliated with Acute Diarrhea

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Pathways related to Acute Diarrhea according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5LTF, MME
29.3LTF, ALB

Compounds for genes affiliated with Acute Diarrhea

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Compounds related to Acute Diarrhea according to GeneCards/GeneDecks:

(show top 50)    (show all 82)
idCompoundScoreTop Affiliating Genes
1toluene diisocyanate449.9MME, IGHE
2heroin44 50 1111.8MME, IGHE
3periodate449.8IGHE, LTF
4sulfisoxazole44 50 61 1112.8ALB, G6PD
5fosinopril44 1110.8MME, ALB
6cefazolin44 1110.8ALB, G6PD
7ciprofloxacin44 50 1111.8G6PD, LTF
8lisinopril44 50 24 1112.8ALB, MME
9hhpa449.8ALB, IGHE
10bismuth44 2410.7LTF, ALB
11ceftriaxone44 1110.7G6PD, ALB
12iohexol449.7LTF, ALB
13enalapril44 50 1111.7ALB, MME
14leupeptin449.7MME, LTF
15sucralfate44 1110.7IGHE, ALB
16ampicillin44 1110.7LTF, ALB
17budesonide44 50 1111.7LTF, IGHE
18cellulose acetate449.7G6PD, ALB
19glutaraldehyde449.6ALB, G6PD
20furosemide44 61 28 50 24 1114.6MME, ALB
21mycophenolic acid44 50 1111.6ALB, IGHE
22propofol44 50 1111.5ALB, IGHE
23probenecid28 44 61 50 1113.5ALB, G6PD
24methacholine44 50 1111.5IGHE, MME, LTF
25capsaicin44 2810.5IGHE, MME, LTF
26captopril44 61 50 28 1113.4MME, ALB
27naloxone44 28 50 1112.4ALB, MME
28aprotinin44 1110.4LTF, MME, IGHE
29pertussis449.3IGHE, LTF
30cyclophosphamide44 50 1111.3IGHE, G6PD, LTF
31sulfamethoxazole50 44 1111.3ALB, G6PD, IGHE
32vitamin b12449.3LTF, ALB, G6PD
33n acetylcysteine449.3LTF, G6PD, IGHE
34mannitol44 1110.3IGHE, G6PD, ALB
35thyroxine44 2410.2ALB, G6PD, IGHE
36folate449.2ALB, G6PD, IGHE
37cyclosporin a44 28 6111.1LTF, MME, IGHE
38actinomycin d449.0IGHE, G6PD, MME, LTF
39adenylate449.0IGHE, G6PD, MME, LTF
40citrate448.9G6PD, MME, ALB, LTF
41lactate448.9IGHE, G6PD, MME, ALB
42estrogen448.9IGHE, G6PD, MME, LTF
43vitamin a44 24 1110.8IGHE, MME, ALB, LTF
44testosterone44 61 24 1111.8IGHE, G6PD, MME, ALB
45indomethacin44 28 61 1111.8LTF, ALB, MME, IGHE
46histamine44 28 2410.8LTF, ALB, MME, IGHE
47aspartate448.8LTF, ALB, G6PD, IGHE
48glutamine448.7LTF, G6PD, IGHE
49ascorbic acid44 249.4LTF, ALB, MME, G6PD, IGHE
50creatinine448.4IGHE, G6PD, MME, ALB, LTF

GO Terms for genes affiliated with Acute Diarrhea

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Cellular components related to Acute Diarrhea according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular vesicular exosomeGO:0700628.5LTF, ALB, MME, G6PD

Biological processes related to Acute Diarrhea according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1kidney developmentGO:0018229.2MME, PYGO1
2retina homeostasisGO:0018959.0LTF, ALB

Products for genes affiliated with Acute Diarrhea

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  • Antibodies
  • Proteins
  • Lysates

Sources for Acute Diarrhea

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet