MCID: ACT004
MIFTS: 35

Acute Diarrhea malady

Summaries for Acute Diarrhea

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8Disease Ontology, 32MalaCards
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Disease Ontology:8 A diarrhea that is of rapid onset and course characterized by frequent loose or liquid bowel movements. acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide.

MalaCards: Acute Diarrhea is related to diarrhea and hepatitis. An important gene associated with Acute Diarrhea is PITX1 (paired-like homeodomain 1), and among its related pathways are Selected targets of ESR1 and Selected targets of C/EBPalpha. The compounds toluene diisocyanate and heroin have been mentioned in the context of this disorder. Affiliated tissues include breast, small intestine and bone.

Aliases & Classifications for Acute Diarrhea

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS
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Aliases & Descriptions:

acute diarrhea 8 10 60


External Ids:

Disease Ontology8 DOID:0050140

Related Diseases for Acute Diarrhea

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Sources:
17GeneCards, 18GeneDecks
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Diseases in the Chronic Diarrhea Due to Guanylate Cyclase 2c Overactivity family:

acute diarrhea Inflammatory Diarrhea
Diarrhea

Diseases related to Acute Diarrhea via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 119)
idRelated DiseaseScoreTop Affiliating Genes
1diarrhea31.9ALB, LTF
2hepatitis30.1ALB, LTF
3protein-energy malnutrition29.9ALB
4malaria29.8ALB, G6PD
5cholera10.3
6cryptosporidiosis10.1
7shigellosis10.1
8influenza10.1
9pneumonia10.0MME
10leukemia10.0MME
11meningitis10.0ALB
12hepatitis c10.0ALB
13lung cancer10.0ALB
14cholangitis10.0ALB
15viral hepatitis10.0G6PD
16peritonitis10.0ALB
17sickle cell disease10.0G6PD
18tuberculosis10.0ALB
19senile cataract10.0G6PD
20nephrotic syndrome10.0ALB
21colorectal cancer10.0LTF
22adenocarcinoma10.0MME
23neonatal jaundice10.0G6PD
24short bowel syndrome10.0ALB
25gastritis10.0LTF
26homocystinuria10.0G6PD
27sjogren's syndrome10.0LTF
28cataract10.0G6PD
29churg-strauss syndrome10.0LTF
30autoimmune hemolytic anemia10.0G6PD
31allergic rhinitis10.0IGHE
32congenital hypothyroidism10.0G6PD
33eosinophilic gastroenteritis10.0IGHE
34strongyloidiasis10.0IGHE
35conjunctivitis10.0IGHE
36bronchiolitis10.0IGHE
37amyloidosis10.0ALB, MME
38membranous glomerulonephritis10.0ALB, MME
39sinusitis10.0IGHE
40dental caries10.0LTF
41kernicterus10.0ALB, G6PD
42bilirubin metabolic disorder10.0ALB, G6PD
43iron deficiency anemia10.0LTF, G6PD
44amyloid tumor10.0LTF, MME
45vasculitis10.0LTF, ALB
46acute kidney failure10.0G6PD, ALB
47asthma10.0IGHE, MME
48diabetes mellitus10.0ALB, G6PD
49rhinitis10.0IGHE, ALB
50otitis media10.0IGHE, LTF

Graphical network of the top 20 diseases related to Acute Diarrhea:



Diseases related to acute diarrhea

Clinical Features for Acute Diarrhea

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Drugs & Therapeutics for Acute Diarrhea

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Acute Diarrhea

Drug clinical trials:

Search ClinicalTrials for Acute Diarrhea

Search NIH Clinical Center for Acute Diarrhea

Search CenterWatch for Acute Diarrhea

Genetic Tests for Acute Diarrhea

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Anatomical Context for Acute Diarrhea

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Sources:
32MalaCards
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MalaCards organs/tissues related to Acute Diarrhea:

32
Breast, Small intestine, Bone, Bone marrow, T cells, Appendix

Animal Models for Acute Diarrhea or affiliated genes

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Publications for Acute Diarrhea

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Sources:
50PubMed
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Articles related to Acute Diarrhea:

(show top 50)    (show all 540)
idTitleAuthorsYear
1
The effect of acute serotonergic modulation on rectal motor function in diarrhea-predominant irritable bowel syndrome and healthy controls. (22890209)
2012
2
Translational approaches for pharmacotherapy development for acute diarrhea. (22266149)
2012
3
Detection of a bocavirus circular genome in fecal specimens from children with acute diarrhea in Beijing, China. (23133667)
2012
4
The fecal microbiome in dogs with acute diarrhea and idiopathic inflammatory bowel disease. (23300577)
2012
5
Genetic analysis of hepatitis A virus variants circulating among children presenting with acute diarrhea in Cameroon. (22431020)
2012
6
Genotype diversity of group A rotavirus strains in children with acute diarrhea in urban Burkina Faso, 2008-2010. (21678452)
2011
7
Characterization of human rotavirus recovered from children with acute diarrhea in Kinshasa, Democratic Republic Of Congo. (20684702)
2010
8
Diarrhea during the conditioning regimen is correlated with the occurrence of severe acute graft-versus-host disease through systemic release of inflammatory cytokines. (20546909)
2010
9
Analysis of factors influencing the overall effect of racecadotril on childhood acute diarrhea. Results from a real-world and post-authorization surveillance study in Venezuela. (20668711)
2010
10
Zinc and copper supplementation in acute diarrhea in children: a double-blind randomized controlled trial. (19416499)
2009
11
Molecular studies of fecal anaerobic commensal bacteria in acute diarrhea in children. (18493205)
2008
12
Identification of a novel picornavirus related to cosaviruses in a child with acute diarrhea. (19102772)
2008
13
Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort. (17519069)
2007
14
Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis. (17388664)
2007
15
Etiology of acute diarrhea in children and adults in Tunis, Tunisia, with emphasis on diarrheagenic Escherichia coli: prevalence, phenotyping, and molecular epidemiology. (17827382)
2007
16
Therapeutic value of a Lactobacillus gasseri and Bifidobacterium longum fixed bacterium combination in acute diarrhea: a randomized, double-blind, controlled clinical trial. (16724575)
2006
17
Thin layer chromatography in children with sugar intolerance in acute diarrhea. (16763348)
2006
18
Zinc in the treatment of acute diarrhea: current status and assessment. (16762641)
2006
19
Incidence and clinical manifestations of rotavirus infection among children with acute diarrhea admitted at Buri Ram Hospital, Thailand. (17333764)
2006
20
Consensus Statement of IAP National Task Force: status report on management of acute diarrhea. (15123862)
2004
21
Effects of long-term consumption of a fermented infant formula (with Bifidobacterium breve c50 and Streptococcus thermophilus 065) on acute diarrhea in healthy infants. (15269618)
2004
22
Epidemiologic and clinical characteristics of acute diarrhea with emphasis on Entamoeba histolytica infections in preschool children in an urban slum of Dhaka, Bangladesh. (14640500)
2003
23
Severe acute diarrhea. (14696306)
2003
24
Detection, subgroup specificity, and genotype diversity of rotavirus strains in children with acute diarrhea in Paraguay. (11980947)
2002
25
A double blind, randomized, placebo-controlled study of SP-303 (Provir) in the symptomatic treatment of acute diarrhea among travelers to Jamaica and Mexico. (12385443)
2002
26
Effectiveness and efficacy of zinc for the treatment of acute diarrhea in young children. (11986453)
2002
27
Effect of probiotic Lactobacillus strains in young children hospitalized with acute diarrhea. (12150178)
2002
28
Diversity of rotavirus strains among children with acute diarrhea in China: 1998-2000 surveillance study. (11980983)
2002
29
Molecular Epidemiology of Group A Rotavirus Causing Acute Diarrhea in Infants and Young Children in Rio de Janeiro, Brazil, 1997-1998. (11096435)
1999
30
Absorption of nutrients from an energy-dense diet liquefied with amylase from germinated wheat in infants with acute diarrhea. (9106095)
1997
31
Parental awareness and practices in acute diarrhea. (8617539)
1995
32
A randomized controlled trial of vitamin A supplementation in acute diarrhea. (8617529)
1995
33
Loperamide oxide in the treatment of acute diarrhea in adults. (7697694)
1994
34
The nutritional management of acute diarrhea in young infants. (7815235)
1994
35
Use of nonhuman milks in the dietary management of young children with acute diarrhea: a meta-analysis of clinical trials. (8265318)
1994
36
Association of rotavirus and human immunodeficiency virus infection in children hospitalized with acute diarrhea, Lusaka, Zambia. (8133106)
1994
37
Acute diarrhea and oral rehydration solutions. (8280043)
1993
38
Learning by teaching. A resident-taught oral therapy program for acute diarrhea. (1395367)
1992
39
Confirmation of a viral agent as a cause of acute diarrhea. (1573501)
1992
40
Mortality associated with acute watery diarrhea, dysentery and persistent diarrhea in rural north India. (1421937)
1992
41
Bismuth subsalicylate in the treatment of acute diarrhea in children: a clinical study. (1984613)
1991
42
Acute diarrhea in adults. Management, with emphasis on oral rehydration therapy. (2587459)
1989
43
Frequency of Campylobacter jejuni and other agents of acute diarrhea in Venezuelan children. (3442715)
1987
44
Symposium on Calf Diarrhea. Appendix 4. Field technique for estimating severity of dehydration, volume of fluid necessary for rehydration, and average bicarbonate deficit for a 40-kg neonatal calf with acute diarrhea. (3878218)
1985
45
Acute diarrhea in horses of the Potomac River area: examination for clostridial toxins. (6469842)
1984
46
Bacterial agents in acute diarrhea. (7079686)
1982
47
Maternal beliefs regarding diet during acute diarrhea. (7327655)
1981
48
Ad libitum oral glucose-electrolyte therapy for acute diarrhea in Apache children. (4581015)
1973
49
SPECTRUM OF ACUTE DIARRHEA IN A GENERAL HOSPITAL. 2. SALMONELLOSIS; REVIEW OF 124 CASES. (14340520)
1965
50
CLINICO-PATHOLOGICAL CONFERENCE. ACUTE ABDOMINAL PAIN, BLOODY DIARRHEA AND ANURIA. (14076465)
1964

Genetic Variations for Acute Diarrhea

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Expression for genes affiliated with Acute Diarrhea

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Acute Diarrhea

Search GEO for disease gene expression data for Acute Diarrhea.

Pathways for genes affiliated with Acute Diarrhea

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12EMD Millipore
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Pathways related to Acute Diarrhea according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5MME, LTF
29.3ALB, LTF

Compounds for genes affiliated with Acute Diarrhea

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 59Tocris Bioscience, 24HMDB, 28IUPHAR
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Compounds related to Acute Diarrhea according to GeneCards/GeneDecks:

(show top 50)    (show all 62)
idCompoundScoreTop Affiliating Genes
1toluene diisocyanate449.9IGHE, MME
2heroin44 49 1111.9MME, IGHE
3periodate449.8LTF, IGHE
4fosinopril44 1110.8MME, ALB
5sulfisoxazole44 59 49 1112.8ALB, G6PD
6cefazolin44 1110.8ALB, G6PD
7lisinopril44 11 2411.8ALB, MME
8hhpa449.8ALB, IGHE
9ceftriaxone44 1110.7G6PD, ALB
10bismuth44 2410.7ALB, LTF
11enalapril44 49 1111.7MME, ALB
12mannitol44 1110.7ALB, IGHE
13leupeptin449.7LTF, MME
14iohexol449.7LTF, ALB
15sucralfate44 1110.7IGHE, ALB
16ampicillin44 1110.7ALB, LTF
17budesonide44 49 1111.7IGHE, LTF
18cellulose acetate449.7ALB, G6PD
19furosemide44 49 59 28 11 2414.6ALB, MME
20glutaraldehyde449.6G6PD, ALB
21mycophenolic acid44 49 1111.6IGHE, ALB
22captopril44 28 49 59 1113.6ALB, MME
23propofol44 49 1111.6ALB, IGHE
24probenecid44 28 59 49 1113.5ALB, G6PD
25pertussis449.5LTF, IGHE
26methacholine44 1110.5IGHE, LTF, MME
27capsaicin44 2810.5MME, LTF, IGHE
28naloxone44 49 28 1112.4MME, ALB
29aprotinin44 1110.4MME, LTF, IGHE
30cyclophosphamide44 49 1111.3G6PD, IGHE, LTF
31diazepam44 49 28 1112.3ALB, LTF
32protamine449.3IGHE, LTF
33sulfamethoxazole44 49 1111.3G6PD, IGHE, ALB
34vitamin b12449.3ALB, LTF, G6PD
35n acetylcysteine449.3LTF, IGHE, G6PD
36thyroxine44 2410.2G6PD, IGHE, ALB
37folate449.2G6PD, IGHE, ALB
38hypoxanthine44 11 2411.2LTF, G6PD
39actinomycin d449.0G6PD, IGHE, LTF, MME
40adenylate448.9MME, LTF, IGHE, G6PD
41citrate448.9G6PD, LTF, MME, ALB
42lactate448.9G6PD, IGHE, MME, ALB
43vitamin a44 11 2410.8IGHE, LTF, MME, ALB
44indomethacin44 59 28 1111.8ALB, MME, LTF, IGHE
45estrogen448.8G6PD, IGHE, LTF, MME
46histamine44 28 2410.8IGHE, LTF, MME, ALB
47testosterone44 59 11 2411.8ALB, MME, IGHE, G6PD
48aspartate448.8G6PD, IGHE, LTF, ALB
49ascorbic acid44 249.4ALB, MME, LTF, IGHE, G6PD
50creatinine448.4ALB, MME, LTF, IGHE, G6PD

GO Terms for genes affiliated with Acute Diarrhea

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Products for genes affiliated with Acute Diarrhea

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Acute Diarrhea

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet