MCID: ACT004
MIFTS: 35

Acute Diarrhea malady

Summaries for Acute Diarrhea

About this section
Sources:
8Disease Ontology, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Disease Ontology:8 A diarrhea that is of rapid onset and course characterized by frequent loose or liquid bowel movements. acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide.

MalaCards: Acute Diarrhea is related to diarrhea and hepatitis. An important gene associated with Acute Diarrhea is PITX1 (paired-like homeodomain 1), and among its related pathways are Selected targets of ESR1 and Selected targets of C/EBPalpha. The compounds toluene diisocyanate and heroin have been mentioned in the context of this disorder. Affiliated tissues include breast, small intestine and bone marrow.

Aliases & Classifications for Acute Diarrhea

About this section
Sources:
8Disease Ontology, 10DISEASES, 60UMLS
See all sources

Aliases & Descriptions:

acute diarrhea 8 10 60


External Ids:

Disease Ontology8 DOID:0050140

Related Diseases for Acute Diarrhea

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Chronic Diarrhea Due to Guanylate Cyclase 2c Overactivity family:

acute diarrhea Inflammatory Diarrhea
Diarrhea

Diseases related to Acute Diarrhea via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 119)
idRelated DiseaseScoreTop Affiliating Genes
1diarrhea31.9ALB, LTF
2hepatitis30.1ALB, LTF
3protein-energy malnutrition29.9ALB
4malaria29.8ALB, G6PD
5cholera10.3
6cryptosporidiosis10.1
7shigellosis10.1
8influenza10.1
9pneumonia10.0MME
10leukemia10.0MME
11meningitis10.0ALB
12hepatitis c10.0ALB
13lung cancer10.0ALB
14cholangitis10.0ALB
15viral hepatitis10.0G6PD
16peritonitis10.0ALB
17sickle cell disease10.0G6PD
18tuberculosis10.0ALB
19senile cataract10.0G6PD
20nephrotic syndrome10.0ALB
21colorectal cancer10.0LTF
22adenocarcinoma10.0MME
23neonatal jaundice10.0G6PD
24short bowel syndrome10.0ALB
25gastritis10.0LTF
26homocystinuria10.0G6PD
27sjogren's syndrome10.0LTF
28cataract10.0G6PD
29churg-strauss syndrome10.0LTF
30autoimmune hemolytic anemia10.0G6PD
31allergic rhinitis10.0IGHE
32congenital hypothyroidism10.0G6PD
33eosinophilic gastroenteritis10.0IGHE
34strongyloidiasis10.0IGHE
35conjunctivitis10.0IGHE
36bronchiolitis10.0IGHE
37amyloidosis10.0ALB, MME
38membranous glomerulonephritis10.0ALB, MME
39sinusitis10.0IGHE
40dental caries10.0LTF
41kernicterus10.0ALB, G6PD
42bilirubin metabolic disorder10.0ALB, G6PD
43iron deficiency anemia10.0LTF, G6PD
44amyloid tumor10.0LTF, MME
45vasculitis10.0LTF, ALB
46acute kidney failure10.0G6PD, ALB
47asthma10.0IGHE, MME
48diabetes mellitus10.0ALB, G6PD
49rhinitis10.0IGHE, ALB
50otitis media10.0IGHE, LTF

Graphical network of the top 20 diseases related to Acute Diarrhea:



Diseases related to acute diarrhea

Clinical Features for Acute Diarrhea

About this section

Drugs & Therapeutics for Acute Diarrhea

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Acute Diarrhea

Drug clinical trials:

Search ClinicalTrials for Acute Diarrhea

Search NIH Clinical Center for Acute Diarrhea

Search CenterWatch for Acute Diarrhea

Genetic Tests for Acute Diarrhea

About this section

Anatomical Context for Acute Diarrhea

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Acute Diarrhea:

32
Breast, Small intestine, Bone marrow, Bone, T cells, Appendix

Animal Models for Acute Diarrhea or affiliated genes

About this section

Publications for Acute Diarrhea

About this section
Sources:
50PubMed
See all sources

Articles related to Acute Diarrhea:

(show top 50)    (show all 540)
idTitleAuthorsYear
1
Therapeutic effects of oral zinc supplementation on acute watery diarrhea with moderate dehydration: a double-blind randomized clinical trial. (23825888)
2013
2
Acute diarrhea in hospitalized children of the municipality of Juiz de Fora, MG, Brazil: prevalence and risk factors associated with disease severity. (23329220)
2012
3
Simultaneous investigation of influenza and enteric viruses in the stools of adult patients consulting in general practice for acute diarrhea. (22709374)
2012
4
ESBL-producing Escherichia coli isolated from children with acute diarrhea - antimicrobial susceptibility, adherence patterns and phylogenetic background. (23214282)
2012
5
Seasonal variation of enteropathogens in infants and preschoolers with acute diarrhea in western Mexico. (20706147)
2010
6
An autopsy case of disseminated cryptococcosis manifesting as acute diarrhea in a patient with primary biliary cirrhosis. (20720361)
2010
7
Image of the month. Acute diarrhea caused by a rectovesical fistula after laparoscopic prostatectomy. (19932767)
2010
8
Anti-diarrheal effects of diosmectite in the treatment of acute diarrhea in children: a review. (19301931)
2009
9
Acute diarrhea in children in europe: do we know how to treat it? (18460973)
2008
10
Case-Control Study of acute diarrhea in Children. (23343994)
2008
11
Phase III, double-blind study of depot octreotide versus placebo in the prevention of acute diarrhea in patients receiving pelvic radiation therapy: results of North Central Cancer Treatment Group N00CA. (18768432)
2008
12
Field evaluation of a rota- and adenovirus immunochromatographic assay using stool samples from children with acute diarrhea in Ghana. (17596373)
2007
13
Changing patterns of antimicrobial susceptibility of Shigella serotypes isolated from children with acute diarrhea in Manipal, South India, a 5 year study. (18041303)
2007
14
Estimation of serum zinc and copper in children with acute diarrhea. (17205994)
2006
15
Virus diversity of acute diarrhea in tropical highlands. (17357570)
2006
16
Racecadotril-is there enough evidence to recommend it for treatment of acute diarrhea? (15623899)
2004
17
Oral rehydration solution containing a mixture of non-digestible carbohydrates in the treatment of acute diarrhea: a multicenter randomized placebo controlled study on behalf of the ESPGHAN working group on intestinal infections. (15319622)
2004
18
Current concepts in management of acute diarrhea. (12768058)
2003
19
First detection of group C rotavirus in children with acute diarrhea in Spain. (12557002)
2003
20
Efficacy of zinc-fortified oral rehydration solution in 6- to 35-month-old children with acute diarrhea. (12410197)
2002
21
Oral bacterial therapy promotes recovery from acute diarrhea in children. (11729708)
2001
22
Practical management of acute diarrhea. (11446600)
2001
23
Clinical evaluation of the addition of lyophilized, heat-killed Lactobacillus acidophilus LB to oral rehydration therapy in the treatment of acute diarrhea in children. (10630442)
2000
24
Acute diarrhea: a practical review. (10378626)
1999
25
Oral rehydration solution for acute diarrhea prevents subsequent unscheduled follow-up visits. (10469812)
1999
26
Nutritional management of acute diarrhea. (9785356)
1998
27
Carbohydrate malabsorption in acute diarrhea. (7883363)
1994
28
QA methods improve quality of cholera / acute diarrhea care in local health districts in Ecuador. (12319099)
1994
29
Cryptosporidiosis in Myanmar infants with acute diarrhea. (7667708)
1994
30
Enterocytozoon bieneusi infection in an immunocompetent patient who had acute diarrhea and who was not infected with the human immunodeficiency virus. (7811871)
1994
31
Maternal beliefs regarding diet during acute diarrhea. (8282397)
1993
32
Mortality associated with acute watery diarrhea, dysentery and persistent diarrhea in rural North India. (12286021)
1992
33
Treatment of acute diarrhea in children. (1442538)
1992
34
Action of acetorphan, an enkephalinase inhibitor, in acute diarrhea]. (1285638)
1992
35
Enterotoxins and adhesins of enterotoxigenic Escherichia coli: are they risk factors for acute diarrhea in the community? (1973696)
1990
36
The somatostatin analog octreotide in the management of the secretory diarrhea of the acute intestinal graft-versus-host disease in a patient after bone marrow transplantation. (2360261)
1990
37
Spiramycin vs. placebo for treatment of acute diarrhea caused by Cryptosporidium. (2652084)
1989
38
Aluminium hydroxide and cholestyramine in the treatment of acute diarrhea. (2659716)
1989
39
Trace mineral balance during acute diarrhea in infants. (3411389)
1988
40
Refeeding during recovery from acute diarrhea. (3339504)
1988
41
Simple clinical score and laboratory-based method to predict bacterial etiology of acute diarrhea in childhood. (3431982)
1987
42
More on cola drinks and rehydration in acute diarrhea. (3796708)
1987
43
Comparison between children treated at home and those requiring hospital admission for rotavirus and other enteric pathogens associated with acute diarrhea in Melbourne, Australia. (3020082)
1986
44
Nonfluid therapy and selected chemoprophylaxis of acute diarrhea. (3893119)
1985
45
Oral rehydration, rapid feeding, and cholestyramine for treatment of acute diarrhea. (4020569)
1985
46
Dietary treatment of acute diarrhea: comparison between cow's milk and a soy formula without disaccharides. (6541707)
1984
47
A semi-elemental diet with low osmolarity and high content of hydrolyzed lactalbumin in the treatment of acute diarrhea in malnourished children. (6442856)
1984
48
Fluid therapy in horses with acute diarrhea. (552690)
1979
49
Clinical assessment of hetacillin in acute diarrhea of malnourished infants. (4998182)
1967
50
Spectrum of acute diarrhea in a general hospital. 4. "Antibiotic bowel" and pseudomembranous enterocolitis. (5827657)
1965

Genetic Variations for Acute Diarrhea

About this section

Expression for genes affiliated with Acute Diarrhea

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Acute Diarrhea

Search GEO for disease gene expression data for Acute Diarrhea.

Pathways for genes affiliated with Acute Diarrhea

About this section
Sources:
12EMD Millipore
See all sources

Pathways related to Acute Diarrhea according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5MME, LTF
29.3ALB, LTF

Compounds for genes affiliated with Acute Diarrhea

About this section
Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 59Tocris Bioscience, 24HMDB, 28IUPHAR
See all sources

Compounds related to Acute Diarrhea according to GeneCards/GeneDecks:

(show top 50)    (show all 62)
idCompoundScoreTop Affiliating Genes
1toluene diisocyanate449.9IGHE, MME
2heroin44 49 1111.9IGHE, MME
3periodate449.8LTF, IGHE
4sulfisoxazole44 59 49 1112.8G6PD, ALB
5fosinopril44 1110.8MME, ALB
6cefazolin44 1110.8ALB, G6PD
7lisinopril44 11 2411.8MME, ALB
8hhpa449.8ALB, IGHE
9ceftriaxone44 1110.7ALB, G6PD
10bismuth44 2410.7ALB, LTF
11enalapril44 49 1111.7MME, ALB
12mannitol44 1110.7IGHE, ALB
13leupeptin449.7LTF, MME
14iohexol449.7LTF, ALB
15sucralfate44 1110.7ALB, IGHE
16ampicillin44 1110.7LTF, ALB
17budesonide44 49 1111.7IGHE, LTF
18cellulose acetate449.7ALB, G6PD
19furosemide44 49 59 28 11 2414.6ALB, MME
20glutaraldehyde449.6G6PD, ALB
21mycophenolic acid44 49 1111.6IGHE, ALB
22propofol44 49 1111.6ALB, IGHE
23probenecid44 28 59 49 1113.5ALB, G6PD
24pertussis449.5IGHE, LTF
25captopril44 28 49 59 1113.5ALB, MME
26methacholine44 1110.5IGHE, LTF, MME
27capsaicin44 2810.5LTF, IGHE, MME
28naloxone44 49 28 1112.4ALB, MME
29aprotinin44 1110.4LTF, IGHE, MME
30cyclophosphamide44 49 1111.3LTF, IGHE, G6PD
31diazepam44 49 28 1112.3LTF, ALB
32protamine449.3IGHE, LTF
33sulfamethoxazole44 49 1111.3IGHE, G6PD, ALB
34vitamin b12449.3LTF, ALB, G6PD
35n acetylcysteine449.3G6PD, IGHE, LTF
36thyroxine44 2410.2G6PD, ALB, IGHE
37folate449.2G6PD, ALB, IGHE
38hypoxanthine44 11 2411.2LTF, G6PD
39actinomycin d449.0IGHE, G6PD, MME, LTF
40adenylate448.9IGHE, LTF, G6PD, MME
41citrate448.9LTF, G6PD, MME, ALB
42lactate448.9ALB, MME, IGHE, G6PD
43vitamin a44 11 2410.8LTF, IGHE, ALB, MME
44indomethacin44 59 28 1111.8ALB, IGHE, LTF, MME
45estrogen448.8G6PD, MME, IGHE, LTF
46histamine44 28 2410.8LTF, ALB, MME, IGHE
47testosterone44 59 11 2411.8G6PD, ALB, MME, IGHE
48aspartate448.8ALB, LTF, IGHE, G6PD
49ascorbic acid44 249.4ALB, IGHE, G6PD, LTF, MME
50creatinine448.4G6PD, IGHE, MME, ALB, LTF

GO Terms for genes affiliated with Acute Diarrhea

About this section

Products for genes affiliated with Acute Diarrhea

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Acute Diarrhea

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet