MCID: ACT004
MIFTS: 37

Acute Diarrhea malady

Genetic diseases, Gastrointestinal diseases, Rare diseases categories

Aliases & Classifications for Acute Diarrhea

About this section

Acute Diarrhea, Aliases & Descriptions:

Name: Acute Diarrhea 9 11 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Gastrointestinal diseases


External Ids:

Disease Ontology9 DOID:0050140

Summaries for Acute Diarrhea

About this section


Disease Ontology:9 A diarrhea that is of rapid onset and course characterized by frequent loose or liquid bowel movements. acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide.

MalaCards based summary: Acute Diarrhea is related to diarrhea and hepatitis. An important gene associated with Acute Diarrhea is PITX1 (paired-like homeodomain 1), and among its related pathways are Selected targets of ESR1 and Selected targets of C EBPalpha. The compounds toluene diisocyanate and heroin have been mentioned in the context of this disorder. Affiliated tissues include small intestine, breast and t cells, and related mouse phenotype homeostasis/metabolism.

Wikipedia:63 Gastroenteritis or infectious diarrhea is a medical condition from inflammation (\"-itis\") of the... more...

Related Diseases for Acute Diarrhea

About this section

Diseases in the Diarrhea family:

Diarrhea 7 Diarrhea 6
Chronic Diarrhea Due to Guanylate Cyclase 2c Overactivity Inflammatory Diarrhea
acute diarrhea

Diseases related to Acute Diarrhea via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 101)
idRelated DiseaseScoreTop Affiliating Genes
1diarrhea32.2LTF, ALB
2hepatitis30.2ALB, LTF
3malaria30.2G6PD, ALB
4primary biliary cirrhosis30.0ALB, LTF
5blindness10.6
6cholera10.4
7cholangitis10.4ALB
8eosinophilic gastroenteritis10.3IGHE
9strongyloidiasis10.3IGHE
10bronchiolitis10.2IGHE
11cryptosporidiosis10.2
12membranous glomerulonephritis, antenatal10.2ALB, MME
13kernicterus10.2ALB, G6PD
14bilirubin metabolic disorder10.1G6PD, ALB
15iron deficiency anemia10.1LTF, G6PD
16acute kidney failure10.1ALB, G6PD
17shigellosis10.1
18metabolic acidosis10.1
19gastroenteritis10.1
20influenza10.1
21mastitis10.1LTF, ALB
22amyloidosis10.1ALB, MME
23asthma10.1IGHE, MME
24ulcerative colitis10.1LTF, ALB
25crohn's disease10.0LTF, ALB
26angioedema10.0IGHE, MME
27hypertension, essential10.0ALB, MME
28respiratory failure10.0G6PD, IGHE
29vasculitis10.0LTF, ALB
30rhinitis10.0IGHE, ALB
31primary hyperoxaluria10.0ALB, MME, G6PD
32otitis media10.0LTF, IGHE
33deficiency anemia10.0G6PD, MME, ALB
34viral infectious disease10.0PITX1, G6PD, MME
35reticular dysgenesis10.0
36hirschsprung disease 110.0
37hyper-igd syndrome10.0
38bloom syndrome10.0
39kawasaki disease10.0
40diabetes insipidus, neurohypophyseal10.0
41acrodermatitis enteropathica10.0
42hiv-110.0
43multiple endocrine neoplasia iia10.0
44familial mediterranean fever, ar10.0
45agammaglobulinemia, x-linked 110.0
46autoimmune hepatitis10.0
47cerebral palsy10.0
48dengue disease10.0
49rift valley fever10.0
50good syndrome10.0

Graphical network of the top 20 diseases related to Acute Diarrhea:



Diseases related to acute diarrhea

Symptoms for Acute Diarrhea

About this section

Drugs & Therapeutics for Acute Diarrhea

About this section

Drug clinical trials:

Search ClinicalTrials for Acute Diarrhea

Search NIH Clinical Center for Acute Diarrhea

Genetic Tests for Acute Diarrhea

About this section

Anatomical Context for Acute Diarrhea

About this section

MalaCards organs/tissues related to Acute Diarrhea:

31
Small intestine, Breast, T cells, Appendix

Animal Models for Acute Diarrhea or affiliated genes

About this section

MGI Mouse Phenotypes related to Acute Diarrhea:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.9LTF, ALB, MME, G6PD, IGHE

Publications for Acute Diarrhea

About this section

Articles related to Acute Diarrhea:

(show top 50)    (show all 521)
idTitleAuthorsYear
1
Effectiveness of multifaceted interventions on rational use of antibiotics for patients with upper respiratory tract infections and acute diarrhea. (24772576)
2014
2
Thymic stromal lymphopoietin-mediated epicutaneous inflammation promotes acute diarrhea and anaphylaxis. (25365222)
2014
3
Therapeutic zinc and copper supplementation in acute diarrhea does not influence short-term morbidity and growth: double-blind randomized controlled trial. (22926212)
2013
4
Enteroaggregative Escherichia coli and acute diarrhea in children: a meta-analysis of South Asian populations. (23179250)
2013
5
Potential impact of influenza A/H1N1 pandemic and hand-gels on acute diarrhea epidemic in France. (24124479)
2013
6
Acute diarrhea in West African children: diverse enteric viruses and a novel parvovirus genus. (22855485)
2012
7
Acute diarrhea among military recruits. (23214210)
2012
8
Acute diarrhea in hospitalized children of the municipality of Juiz de Fora, MG, Brazil: prevalence and risk factors associated with disease severity. (23329220)
2012
9
A prospective study of acute diarrhea in a cohort of United States military personnel on deployment to the Multinational Force and Observers, Sinai, Egypt. (21212203)
2011
10
Seasonal variation of enteropathogens in infants and preschoolers with acute diarrhea in western Mexico. (20706147)
2010
11
Clinical trial on the efficacy of a new symbiotic formulation, Flortec, in patients with acute diarrhea: a multicenter, randomized study in primary care. (20616746)
2010
12
Zinc and copper supplementation in acute diarrhea in children: a double-blind randomized controlled trial. (19416499)
2009
13
Acute diarrhea in hospitalized horses. (19580946)
2009
14
Advances in defining etiology and new therapeutic approaches in acute diarrhea. (17825422)
2007
15
Acute diarrhea in the adult horse: case example and review. (16627106)
2006
16
Cytotoxicity and antimicrobial susceptibility of Clostridium difficile isolated from hospitalized children with acute diarrhea. (16701515)
2004
17
Epidemiologic and clinical characteristics of acute diarrhea with emphasis on Entamoeba histolytica infections in preschool children in an urban slum of Dhaka, Bangladesh. (14640500)
2003
18
Acute diarrhea in frail elderly nursing home patients. (12807595)
2003
19
Detection, subgroup specificity, and genotype diversity of rotavirus strains in children with acute diarrhea in Paraguay. (11980947)
2002
20
A double blind, randomized, placebo-controlled study of SP-303 (Provir) in the symptomatic treatment of acute diarrhea among travelers to Jamaica and Mexico. (12385443)
2002
21
Spectrum of vibrio species associated with acute diarrhea in North Jakarta, Indonesia. (12088614)
2002
22
Surveillance of bacterial pathogens associated with acute diarrhea in Lima, Peru. (10737846)
2000
23
Can malabsorbed carbohydrates be useful in the treatment of acute diarrhea? (11144433)
2000
24
Molecular Epidemiology of Group A Rotavirus Causing Acute Diarrhea in Infants and Young Children in Rio de Janeiro, Brazil, 1997-1998. (11096435)
1999
25
Acute diarrhea: a practical review. (10378626)
1999
26
Use of undiluted whole cow's milk is effective for the routine treatment of children with acute diarrhea and severe dehydration. (9814379)
1998
27
Dietary management of acute diarrhea with local foods in a Guatemalan rural community. (9401505)
1997
28
Evaluation of a simplified HEp-2 cell adherence assay for Escherichia coli isolated from south Indian children with acute diarrhea and controls. (7559981)
1995
29
Composition and preliminary evaluation of a hydrolyzed rice-based oral rehydration solution for the treatment of acute diarrhea in children. (8586781)
1995
30
New developments in acute diarrhea. (8055704)
1994
31
Two-year study of endemic enteric pathogens associated with acute diarrhea in New Caledonia. (8077399)
1994
32
Control randomized study of rehydration/rehydration with dioctahedral smectite in ambulatory Thai infants with acute diarrhea. (7825006)
1994
33
Loperamide oxide in the treatment of acute diarrhea in adults. (7697694)
1994
34
Earth, wind, and fiber: is there a drug to treat acute diarrhea? (7815252)
1994
35
The management of acute diarrhea in children: oral rehydration, maintenance, and nutritional therapy. Centers for Disease Control and Prevention. (1435668)
1992
36
Effect of diosmectite on intestinal permeability changes in acute diarrhea: a double-blind placebo-controlled trial. (1517944)
1992
37
Comparison of glucose/electrolyte and maltodextrin/glycine/glycyl-glycine/electrolyte oral rehydration solutions in acute diarrhea in children. (1779314)
1991
38
Enterotoxins and adhesins of enterotoxigenic Escherichia coli: are they risk factors for acute diarrhea in the community? (1973696)
1990
39
Enteropathogenic serotypes of E. coli in acute diarrhea in Ajmer. (3068136)
1988
40
Detection of enterotoxigenic strains of Escherichia coli in children with acute diarrhea. (3334593)
1987
41
A two-year longitudinal study on the etiology of acute diarrhea in young children in Northern Italy. (2983179)
1985
42
The evaluation and management of acute diarrhea. (6730484)
1984
43
Etiological agents responsible for acute diarrhea in children in an urban community in Burma. (6226849)
1983
44
Nonenteric sources of rotavirus in acute diarrhea. (6273477)
1981
45
Maternal beliefs regarding diet during acute diarrhea. (7327655)
1981
46
Acute diarrhea on an Apache Indian reservation. (4594476)
1974
47
The participation of lactic acid in disturbances of the acid-base balance in acute diarrhea in infants. (5370557)
1969
48
Hypoglycemia in neonatal calves associated with acute diarrhea. (5655836)
1968
49
Spectrum of acute diarrhea in a general hospital. 4. "Antibiotic bowel" and pseudomembranous enterocolitis. (5827657)
1965
50
Spectrum of acute diarrhea in general hospitals. 5. Conclusion. (5827658)
1965

Variations for Acute Diarrhea

About this section

Expression for genes affiliated with Acute Diarrhea

About this section
Search GEO for disease gene expression data for Acute Diarrhea.

Pathways for genes affiliated with Acute Diarrhea

About this section

Pathways related to Acute Diarrhea according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes

Compounds for genes affiliated with Acute Diarrhea

About this section

Compounds related to Acute Diarrhea according to GeneCards Suite gene sharing:

(show top 50)    (show all 82)
idCompoundScoreTop Affiliating Genes
1toluene diisocyanate439.9MME, IGHE
2heroin43 49 1211.8MME, IGHE
3periodate439.8IGHE, LTF
4sulfisoxazole43 49 59 1212.8ALB, G6PD
5fosinopril43 1210.8MME, ALB
6cefazolin43 1210.8ALB, G6PD
7ciprofloxacin43 49 1211.8G6PD, LTF
8lisinopril43 49 24 1212.8ALB, MME
9hhpa439.8ALB, IGHE
10bismuth43 2410.7LTF, ALB
11ceftriaxone43 1210.7G6PD, ALB
12iohexol439.7LTF, ALB
13enalapril43 49 1211.7ALB, MME
14leupeptin439.7MME, LTF
15sucralfate43 1210.7IGHE, ALB
16ampicillin43 1210.7LTF, ALB
17budesonide43 49 1211.7LTF, IGHE
18cellulose acetate439.7G6PD, ALB
19glutaraldehyde439.6ALB, G6PD
20furosemide43 59 28 49 24 1214.6MME, ALB
21mycophenolic acid43 49 1211.6ALB, IGHE
22propofol43 49 1211.5ALB, IGHE
23probenecid28 43 59 49 1213.5ALB, G6PD
24methacholine43 49 1211.5IGHE, MME, LTF
25capsaicin43 2810.5IGHE, MME, LTF
26captopril43 59 49 28 1213.4MME, ALB
27aprotinin43 1210.4LTF, MME, IGHE
28protamine439.4LTF, IGHE
29pertussis439.3IGHE, LTF
30cyclophosphamide43 49 1211.3IGHE, G6PD, LTF
31sulfamethoxazole49 43 1211.3ALB, G6PD, IGHE
32vitamin b12439.3LTF, ALB, G6PD
33n acetylcysteine439.3LTF, G6PD, IGHE
34mannitol43 1210.3IGHE, G6PD, ALB
35thyroxine43 2410.2ALB, G6PD, IGHE
36folate439.2ALB, G6PD, IGHE
37cyclosporin a43 28 5911.1LTF, MME, IGHE
38actinomycin d439.0IGHE, G6PD, MME, LTF
39adenylate439.0IGHE, G6PD, MME, LTF
40citrate438.9G6PD, MME, ALB, LTF
41lactate438.9IGHE, G6PD, MME, ALB
42estrogen438.9IGHE, G6PD, MME, LTF
43vitamin a43 24 1210.8IGHE, MME, ALB, LTF
44testosterone43 59 24 1211.8IGHE, G6PD, MME, ALB
45indomethacin43 28 59 1211.8LTF, ALB, MME, IGHE
46histamine43 28 2410.8LTF, ALB, MME, IGHE
47aspartate438.8LTF, ALB, G6PD, IGHE
48glutamine438.7LTF, G6PD, IGHE
49ascorbic acid43 249.4LTF, ALB, MME, G6PD, IGHE
50creatinine438.4IGHE, G6PD, MME, ALB, LTF

GO Terms for genes affiliated with Acute Diarrhea

About this section

Cellular components related to Acute Diarrhea according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular vesicular exosomeGO:00700628.5LTF, ALB, MME, G6PD

Biological processes related to Acute Diarrhea according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1kidney developmentGO:00018229.2MME, PYGO1
2retina homeostasisGO:00018959.0LTF, ALB

Products for genes affiliated with Acute Diarrhea

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Acute Diarrhea

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet