MCID: ACT004
MIFTS: 34

Acute Diarrhea malady

Summaries for Acute Diarrhea

Sources:
8Disease Ontology, 33MalaCards
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Disease Ontology:8 A diarrhea that is of rapid onset and course characterized by frequent loose or liquid bowel movements. acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide.

MalaCards: Acute Diarrhea is related to hepatitis c and cholera. An important gene associated with Acute Diarrhea is PITX1 (paired-like homeodomain 1), and among its related pathways are Selected targets of ESR1 and Selected targets of C/EBPalpha. The compounds toluene diisocyanate and heroin have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, whole blood and small intestine.

Aliases & Classifications for Acute Diarrhea

Sources:
8Disease Ontology, 10DISEASES, 61UMLS
See all sources

Aliases & Descriptions:

acute diarrhea 8 10 61


External Ids:

Disease Ontology8 DOID:0050140

Related Diseases for Acute Diarrhea

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the diarrhea 5, with tufting enteropathy, congenital family:

chronic diarrhea due to guanylate cyclase 2c overactivity diarrhea with microvillus atrophy 2
acute diarrhea inflammatory diarrhea
diarrhea chronic diarrhea with villous atrophy
congenital chronic diarrhea with protein-losing enteropathy

Diseases related to Acute Diarrhea via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 117)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis c29.9ALB
2cholera10.4
3clostridium difficile10.3
4cryptosporidiosis10.1
5hepatitis d10.1
6shigellosis10.1
7hepatitis a10.1
8pneumonia10.0MME
9leukemia10.0MME
10meningitis10.0ALB
11lung cancer10.0ALB
12cholangitis10.0ALB
13viral hepatitis10.0G6PD
14peritonitis10.0ALB
15sickle cell disease10.0G6PD
16tuberculosis10.0ALB
17senile cataract10.0G6PD
18nephrotic syndrome10.0ALB
19colorectal cancer10.0LTF
20protein-energy malnutrition10.0ALB
21adenocarcinoma10.0MME
22neonatal jaundice10.0G6PD
23short bowel syndrome10.0ALB
24gastritis10.0LTF
25homocystinuria10.0G6PD
26sjogren's syndrome10.0LTF
27cataract10.0G6PD
28churg-strauss syndrome10.0LTF
29autoimmune hemolytic anemia10.0G6PD
30allergic rhinitis10.0IGHE
31congenital hypothyroidism10.0G6PD
32eosinophilic gastroenteritis10.0IGHE
33strongyloidiasis10.0IGHE
34conjunctivitis10.0IGHE
35bronchiolitis10.0IGHE
36amyloidosis10.0ALB, MME
37membranous glomerulonephritis10.0ALB, MME
38sinusitis10.0IGHE
39dental caries10.0LTF
40kernicterus10.0ALB, G6PD
41bilirubin metabolic disorder10.0ALB, G6PD
42diarrhea10.0ALB, LTF
43iron deficiency anemia10.0LTF, G6PD
44amyloid tumor10.0LTF, MME
45vasculitis10.0LTF, ALB
46acute kidney failure10.0G6PD, ALB
47asthma10.0IGHE, MME
48diabetes mellitus10.0ALB, G6PD
49rhinitis10.0IGHE, ALB
50otitis media10.0IGHE, LTF

Graphical network of the top 20 diseases related to Acute Diarrhea:



Diseases related to acute diarrhea

Clinical Features for Acute Diarrhea

Drugs & Therapeutics for Acute Diarrhea

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Acute Diarrhea

Drug clinical trials:

Search ClinicalTrials for Acute Diarrhea

Search NIH Clinical Center for Acute Diarrhea

Search CenterWatch for Acute Diarrhea

Genetic Tests for Acute Diarrhea

Anatomical Context for Acute Diarrhea

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Acute Diarrhea:

33
Bone marrow, Whole blood, Small intestine, Breast, T cells, Appendix

Animal Models for Acute Diarrhea or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Acute Diarrhea

Sources:
51PubMed
See all sources

Articles related to Acute Diarrhea:

(show top 50)    (show all 543)
idTitleAuthorsYear
1
Plasmid-Mediated Sulfamethoxazole Resistance Encoded by the sul2 Gene in the Multidrug-Resistant Shigella flexneri 2a Isolated from Patients with Acute Diarrhea in Dhaka, Bangladesh. (24416393)
2014
2
Sociocultural determinants of anticipated vaccine acceptance for acute watery diarrhea in early childhood in Katanga Province, Democratic Republic of Congo. (23878187)
2013
3
The ideal zinc preparation in the management of acute diarrhea in children. (24130400)
2013
4
Acute appendicitis presenting as acute diarrhea accompanying hypokalemia. (24332249)
2013
5
Viral agents associated with acute diarrhea among outpatient children in southeastern China. (23407102)
2013
6
Can Giardia lamblia infection lower the risk of acute diarrhea among preschool children? (24158113)
2013
7
Laboratory-confirmed cholera and rotavirus among patients with acute diarrhea in four hospitals in Haiti, 2012-2013. (24106190)
2013
8
Enteropathogens in acute diarrhea: a general practice-based study in a Nordic country. (22057365)
2012
9
A meta-analysis and systematic review on the effect of probiotics in acute diarrhea. (22309079)
2012
10
Antibiotic therapy in acute diarrhea associated with Shigella: what is the best option? (22915254)
2012
11
A prospective study of acute diarrhea in a cohort of United States military personnel on deployment to the Multinational Force and Observers, Sinai, Egypt. (21212203)
2011
12
ORS containing zinc does not reduce duration or stool volume of acute diarrhea in hospitalized children. (21788757)
2011
13
Clinical trial on the efficacy of a new symbiotic formulation, Flortec, in patients with acute diarrhea: a multicenter, randomized study in primary care. (20616746)
2010
14
Prevalence of rotavirus in acute diarrhea and its association with clinical signs and symptoms. (19793895)
2010
15
Predicting grade 3 acute diarrhea during radiation therapy for rectal cancer using a cutoff-dose logistic regression normal tissue complication probability model. (19665323)
2010
16
Validation of a commercial enzyme immunoassay for detection of Clostridium difficile toxins in feces of horses with acute diarrhea. (20384955)
2010
17
Albumin versus normal saline for dehydrated term infants with metabolic acidosis due to acute diarrhea. (19158801)
2009
18
Prevalence of VP7 and VP4 genotypes of human group A rotavirus in infants and children with acute diarrhea in a northern city of Bangladesh. (19623146)
2009
19
Dietary intake and clinical response of hospitalized patients with acute diarrhea. (18510202)
2008
20
Detection and characterization of Human caliciviruses associated with sporadic acute diarrhea in adults in Djibouti (horn of Africa). (18337354)
2008
21
Advances in defining etiology and new therapeutic approaches in acute diarrhea. (17825422)
2007
22
Effectiveness and safety of Lactobacillus LB in the treatment of mild acute diarrhea in children. (17460488)
2007
23
Biochemical Identification of Enteroaggregative Escherichia Coli among Infants with Acute Diarrhea from Manipal, India. (21475434)
2007
24
The first outbreak of acute diarrhea due to a pandemic strain of Vibrio parahaemolyticus O3:K6 in Kolkata, India. (16793305)
2007
25
Acute diarrhea during army field exercise in southern China. (14695783)
2004
26
Effect of glutamine supplementation on diarrhea, interleukin-8 and secretory immunoglobulin A in children with acute diarrhea. (15097437)
2004
27
Diffusely adherent Escherichia coli as a cause of acute diarrhea in young children in Northeast Brazil: a case-control study. (11825986)
2002
28
Acute appendicitis presenting as secretory diarrhea. (12037768)
2002
29
A prospective case-control study of the role of astrovirus in acute diarrhea among hospitalized young children. (11398103)
2001
30
Surveillance of bacterial pathogens associated with acute diarrhea in Lima, Peru. (10737846)
2000
31
Can malabsorbed carbohydrates be useful in the treatment of acute diarrhea? (11144433)
2000
32
Loperamide-simethicone vs loperamide alone, simethicone alone, and placebo in the treatment of acute diarrhea with gas-related abdominal discomfort. A randomized controlled trial. (10333820)
1999
33
Evaluation of a simplified HEp-2 cell adherence assay for Escherichia coli isolated from south Indian children with acute diarrhea and controls. (7559981)
1995
34
Management of acute diarrhea in children: lessons learned. (8417427)
1993
35
Smectite in acute diarrhea in children: a double-blind placebo-controlled clinical trial. (8229544)
1993
36
Treatment of acute diarrhea with norfloxacin during Desert Storm deployment. (1510647)
1992
37
Fluid therapy in acute diarrhea. (1818866)
1991
38
Comparison of two oral rehydration solutions in eutrophic infants with moderate acute diarrhea: results of an interim analysis. (2187603)
1990
39
Acute diarrhea in children. (2664748)
1989
40
Strategies for improving the therapeutic patterns used in acute diarrhea in primary medical care units. X. Conclusions and research perspectives. (3245758)
1988
41
Bacterial lipopolysaccharide-induced intestinal microvascular lesions leading to acute diarrhea. (3183065)
1988
42
Predictive value of stool examination in acute diarrhea. (3632285)
1987
43
Efficacy of trimethoprim-sulfamethoxazole in treatment of acute diarrhea in a Mexican pediatric population. (3295163)
1987
44
Enteropathogens associated with acute diarrhea in hospitalized infants. (3007718)
1986
45
Oral glucose-electrolyte solutions as maintenance therapy of acute diarrhea. (3890521)
1985
46
Nutritional management of acute diarrhea: an appraisal of the alternatives. (6364024)
1984
47
Evaluation of clinical criteria for the management of acute diarrhea in infants and children. (6654481)
1983
48
Corn syrup sugars: in vitro and in vivo digestibility and clinical tolerance in acute diarrhea of infancy. (6345742)
1983
49
Protocol: acute diarrhea. (247217)
1978
50
Pyuria in acute infantile diarrhea. (5232170)
1966

Genetic Variations for Acute Diarrhea

Expression for genes affiliated with Acute Diarrhea

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Acute Diarrhea

Search GEO for disease gene expression data for Acute Diarrhea.

Pathways for genes affiliated with Acute Diarrhea

Sources:
12EMD Millipore
See all sources

Pathways related to Acute Diarrhea according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5MME, LTF
29.3ALB, LTF

Compounds for genes affiliated with Acute Diarrhea

Sources:
45Novoseek, 50PharmGKB, 11DrugBank, 60Tocris Bioscience, 24HMDB, 29IUPHAR
See all sources

Compounds related to Acute Diarrhea according to GeneCards/GeneDecks:

(show top 50)    (show all 62)
idCompoundScoreTop Affiliating Genes
1toluene diisocyanate459.9IGHE, MME
2heroin45 50 1111.9MME, IGHE
3periodate459.8LTF, IGHE
4fosinopril45 1110.8MME, ALB
5sulfisoxazole45 60 50 1112.8ALB, G6PD
6cefazolin45 1110.8ALB, G6PD
7lisinopril45 11 2411.8ALB, MME
8hhpa459.8ALB, IGHE
9ceftriaxone45 1110.7G6PD, ALB
10bismuth45 2410.7ALB, LTF
11enalapril45 50 1111.7MME, ALB
12mannitol45 1110.7ALB, IGHE
13leupeptin459.7LTF, MME
14iohexol459.7LTF, ALB
15sucralfate45 1110.7IGHE, ALB
16ampicillin45 1110.7ALB, LTF
17budesonide45 50 1111.7IGHE, LTF
18cellulose acetate459.7ALB, G6PD
19furosemide45 50 60 29 11 2414.6ALB, MME
20glutaraldehyde459.6G6PD, ALB
21mycophenolic acid45 50 1111.6IGHE, ALB
22captopril45 29 50 60 1113.6ALB, MME
23propofol45 50 1111.6ALB, IGHE
24probenecid45 29 60 50 1113.5ALB, G6PD
25pertussis459.5LTF, IGHE
26methacholine45 1110.5IGHE, LTF, MME
27capsaicin45 2910.5MME, LTF, IGHE
28naloxone45 50 29 1112.4MME, ALB
29aprotinin45 1110.4MME, LTF, IGHE
30cyclophosphamide45 50 1111.3G6PD, IGHE, LTF
31diazepam45 50 29 1112.3ALB, LTF
32protamine459.3IGHE, LTF
33sulfamethoxazole45 50 1111.3G6PD, IGHE, ALB
34vitamin b12459.3ALB, LTF, G6PD
35n acetylcysteine459.3LTF, IGHE, G6PD
36thyroxine45 2410.2G6PD, IGHE, ALB
37folate459.2G6PD, IGHE, ALB
38hypoxanthine45 11 2411.2LTF, G6PD
39actinomycin d459.0G6PD, IGHE, LTF, MME
40adenylate458.9MME, LTF, IGHE, G6PD
41citrate458.9G6PD, LTF, MME, ALB
42lactate458.9G6PD, IGHE, MME, ALB
43vitamin a45 11 2410.8IGHE, LTF, MME, ALB
44indomethacin45 60 29 1111.8ALB, MME, LTF, IGHE
45estrogen458.8G6PD, IGHE, LTF, MME
46histamine45 29 2410.8IGHE, LTF, MME, ALB
47testosterone45 60 11 2411.8ALB, MME, IGHE, G6PD
48aspartate458.8G6PD, IGHE, LTF, ALB
49ascorbic acid45 249.4ALB, MME, LTF, IGHE, G6PD
50creatinine458.4ALB, MME, LTF, IGHE, G6PD

GO Terms for genes affiliated with Acute Diarrhea

Products for genes affiliated with Acute Diarrhea

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Acute Diarrhea

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet