ADE
MCID: ACT049
MIFTS: 49

Acute Disseminated Encephalomyelitis (ADE) malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Acute Disseminated Encephalomyelitis

Aliases & Descriptions for Acute Disseminated Encephalomyelitis:

Name: Acute Disseminated Encephalomyelitis 12 50 51 56 14
Acute Disseminated Encephalitis 12 56 69
Adem 12 50 56
Encephalomyelitis, Acute Disseminated 69
Encephalomyelitis Acute Disseminated 52
Ade 50

Characteristics:

Orphanet epidemiological data:

56
acute disseminated encephalomyelitis
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe); Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 56  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:639
MeSH 42 D004673
NCIt 47 C34578
SNOMED-CT 64 83942000
Orphanet 56 ORPHA83597
ICD10 via Orphanet 34 G04.0
ICD10 33 G04.0
UMLS 69 C0014059

Summaries for Acute Disseminated Encephalomyelitis

NINDS : 51 Acute disseminated encephalomyelitis (ADEM) is characterized by a brief but widespread attack of inflammation in the brain and spinal cord that damages myelin – the protective covering of nerve fibers.  ADEM often follows viral or bacterial infections, or less often, vaccination for measles, mumps, or rubella.  The symptoms of ADEM appear rapidly, beginning with encephalitis-like symptoms such as fever, fatigue, headache, nausea and vomiting, and in the most severe cases, seizures and coma.  ADEM typically damages white matter (brain tissue that takes its name from the white color of myelin), leading to neurological symptoms such as visual loss (due to inflammation of the optic nerve) in one or both eyes, weakness even to the point of paralysis, and difficulty coordinating voluntary muscle movements (such as those used in walking).  ADEM is sometimes misdiagnosed as a severe first attack of multiple sclerosis (MS), since the symptoms and the appearance of the white matter injury on brain imaging may be similar.  However, ADEM has several features which differentiate it from MS.  First, unlike MS patients, persons with ADEM will have rapid onset of fever, a history of recent infection or immunization, and some degree of impairment of consciousness, perhaps even coma; these features are not typically seen in MS.  Children are more likely than adults to have ADEM, whereas MS is a rare diagnosis in children.  In addition, ADEM usually consists of a single episode or attack of widespread myelin damage, while MS features many attacks over the course of time. Doctors will often use imaging techniques, such as MRI (magnetic resonance imaging), to search for old and new lesions (areas of damage) on the brain.  The presence of older brain lesions on MRI suggest that the condition may be MS rather than ADEM, since MS can cause brain lesions before symptoms become obvious.  In rare situations, a brain biopsy may be necessary to differentiate between ADEM and some other diseases that involve inflammation and damage to myelin.

MalaCards based summary : Acute Disseminated Encephalomyelitis, also known as acute disseminated encephalitis, is related to hepatitis and aseptic meningitis. An important gene associated with Acute Disseminated Encephalomyelitis is MOG (Myelin Oligodendrocyte Glycoprotein), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Actin Nucleation by ARP-WASP Complex. The drugs Antibodies and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and eye.

Disease Ontology : 12 An encephalomyelitis characterized by inflammation located in brain and located in spinal cord that damages myelin. It usually occurs after viral infection, but also following vaccination, bacterial or parasitic infection.

NIH Rare Diseases : 50 acute disseminated encephalomyelitis (adem) is a neurological condition characterized by a brief but intense attack of inflammation in the brain and spinal cord. this may lead to damage of the layer of insulation around affected the nerves (myelin) within affected areas. adem often follows viral infection, or less often, vaccinations for measles, mumps, or rubella (mmr). symptoms usually appear rapidly, beginning with fever, fatigue, headache, nausea and vomiting. treatment for adem is targeted at suppressing inflammation in the brain using anti-inflammatory drugs.  last updated: 8/16/2016

Wikipedia : 71 Acute disseminated encephalomyelitis (ADEM), or acute demyelinating encephalomyelitis, is a rare... more...

Related Diseases for Acute Disseminated Encephalomyelitis

Diseases related to Acute Disseminated Encephalomyelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 232)
id Related Disease Score Top Affiliating Genes
1 hepatitis 30.2 HLA-B HLA-DRB1 IL10
2 aseptic meningitis 29.8 HLA-B HLA-DRB1
3 swine influenza 29.7 HLA-B HLA-DRB1
4 immunodeficiency 27b, mycobacteriosis, ad 12.0
5 alzheimer disease 11.9
6 renal tubular acidosis, distal, ad 11.8
7 keratosis palmoplantaris striata i, ad 11.8
8 emery-dreifuss muscular dystrophy 2, ad 11.7
9 emery-dreifuss muscular dystrophy 7, ad 11.7
10 epidermolysis bullosa dystrophica, ad 11.7
11 cutis laxa, ad 11.7
12 slowed nerve conduction velocity, ad 11.7
13 spinal muscular atrophy, lower extremity-predominant, 2, ad 11.7
14 familial mediterranean fever, ad 11.7
15 spinal muscular atrophy, lower extremity-predominant 1, ad 11.7
16 dopa-responsive dystonia; segawa syndrome ad 11.7
17 hyper-ige recurrent infection syndrome 11.6
18 alzheimer disease-2 11.5
19 myopathy, centronuclear 11.5
20 transverse myelitis 11.4
21 acute hemorrhagic leukoencephalitis 11.2
22 post-vaccinal encephalitis 11.1
23 immune-mediated encephalomyelitis 11.1
24 postinfectious encephalomyelitis 11.1
25 atopic dermatitis 11.0
26 early-onset, autosomal dominant alzheimer disease 11.0
27 pick disease 11.0
28 influenza 10.3
29 encephalitis 10.3
30 imaizumi kuroki syndrome 10.2 HCRT HLA-DQB1
31 osteogenesis imperfecta congenita, microcephaly, and cataracts 10.2 HLA-DQA1 HLA-DQB1
32 hodgkin's paragranuloma 10.2 HCRT HLA-DQB1
33 myeloid and lymphoid neoplasms with eosinophilia and abnormalities of pdgfra, pdgfrb, and fgfr1 10.2 HLA-B HLA-DQB1
34 childhood electroclinical syndrome 10.2 IL10 IL1B
35 apple allergy 10.2 HLA-DQB1 HLA-DRB1
36 parkinson disease 11 10.2 IL10 IL1B
37 lin-gettig syndrome 10.2 HLA-DQB1 HLA-DRB1
38 midline interhemispheric variant of holoprosencephaly 10.2 HLA-DQB1 HLA-DRB1
39 autosomal dominant intermediate charcot-marie-tooth 10.2 HLA-DQB1 HLA-DRB1
40 renal agenesis meningomyelocele mullerian defect 10.2 HLA-DQB1 HLA-DRB1
41 distal trisomy 14q 10.2 HLA-DQB1 HLA-DRB1
42 cyclosporiasis 10.2 HLA-B IL10
43 malaria 10.2
44 pneumonia 10.2
45 rosacea 10.2 IL10 IL1B
46 linear lichen planus 10.1 HLA-DQB1 HLA-DRB1
47 night blindness 10.1 HLA-DQB1 HLA-DRB1
48 neonatal antiphospholipid syndrome 10.1 HLA-DQB1 HLA-DRB1
49 sacral nerve root cysts 10.1 HLA-B HLA-DRB1
50 penis agenesis 10.1 HLA-DRB1 MOG

Graphical network of the top 20 diseases related to Acute Disseminated Encephalomyelitis:



Diseases related to Acute Disseminated Encephalomyelitis

Symptoms & Phenotypes for Acute Disseminated Encephalomyelitis

Drugs & Therapeutics for Acute Disseminated Encephalomyelitis

Drugs for Acute Disseminated Encephalomyelitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies Phase 4
2 Immunoglobulins Phase 4
3 Vaccines Phase 4
4
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
5
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
6 Antiemetics Phase 3
7 Anti-Inflammatory Agents Phase 3
8 Autonomic Agents Phase 3
9 Gastrointestinal Agents Phase 3
10 glucocorticoids Phase 3
11 Hormone Antagonists Phase 3
12 Hormones Phase 3
13 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
14 Methylprednisolone acetate Phase 3
15 Methylprednisolone Hemisuccinate Phase 3
16 Neuroprotective Agents Phase 3
17 Peripheral Nervous System Agents Phase 3
18 Prednisolone acetate Phase 3
19 Prednisolone hemisuccinate Phase 3
20 Prednisolone phosphate Phase 3
21 Protective Agents Phase 3
22 Antibodies, Antiphospholipid
23 Adjuvants, Immunologic
24 Anti-Bacterial Agents
25 Antibiotics, Antitubercular
26 Anti-Infective Agents
27 Antiviral Agents
28 Interferon Inducers
29 interferons
30 Krestin
31 Radiation-Protective Agents

Interventional clinical trials:


id Name Status NCT ID Phase
1 6-year Antibody Check After Third Vaccination Against Japanese Encephalitis Completed NCT02039440 Phase 4
2 Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone Unknown status NCT00004645 Phase 3
3 Centralized Reading Assessment of Chronic CerebroSpinal Venous Insufficiency (CCSVI) in Patients With Multiple Sclerosis and Other Neurological Diseases Completed NCT02308579
4 A Multicenter Observational Study to Evaluate Pediatric Multiple Sclerosis in Brazil Recruiting NCT03087136
5 Quantitation of McArdle's Sign and Evaluation of Specificity for Multiple Sclerosis Recruiting NCT03122873
6 Biobank For MS And Other Demyelinating Diseases Active, not recruiting NCT00445367

Search NIH Clinical Center for Acute Disseminated Encephalomyelitis

Genetic Tests for Acute Disseminated Encephalomyelitis

Anatomical Context for Acute Disseminated Encephalomyelitis

MalaCards organs/tissues related to Acute Disseminated Encephalomyelitis:

39
Brain, Spinal Cord, Eye, T Cells, Bone, Bone Marrow, Lung

The Foundational Model of Anatomy Ontology organs/tissues related to Acute Disseminated Encephalomyelitis:

18
Brain, Spinal Cord

Publications for Acute Disseminated Encephalomyelitis

Articles related to Acute Disseminated Encephalomyelitis:

(show top 50) (show all 598)
id Title Authors Year
1
Acute disseminated encephalomyelitis in China, Singapore and Japan: a comparison with the USA. ( 28009079 )
2017
2
Acute Disseminated Encephalomyelitis Following Zika Virus Infection. ( 27894121 )
2017
3
Weston-Hurst syndrome: a rare fulminant form of acute disseminated encephalomyelitis (ADEM). ( 27797801 )
2016
4
Acute disseminated encephalomyelitis complicating dengue infection with neuroimaging mimicking multiple sclerosis: A report of two cases. ( 27919476 )
2016
5
Acute disseminated encephalomyelitis in 228 patients: A retrospective, multicenter US study. ( 27906662 )
2016
6
Atypical presentations of acute disseminated encephalomyelitis (ADEM) in HIV infection. ( 27687126 )
2016
7
Acute Disseminated Encephalomyelitis following Vaccination against Hepatitis B in a Child: A Case Report and Literature Review. ( 27478662 )
2016
8
Acute disseminated encephalomyelitis secondary to serogroup B meningococcal vaccine. ( 27772786 )
2016
9
Pandemic H1N1 Vaccination and Incidence of Acute Disseminated Encephalomyelitis in Manitoba. ( 27608932 )
2016
10
Bilateral abducens nerve palsy in an infant case of fulminant acute disseminated encephalomyelitis: a case report. ( 27782818 )
2016
11
Acute disseminated encephalomyelitis in 228 patients: A retrospective, multicenter US study. ( 27164698 )
2016
12
Neuroleptic Malignant Syndrome Associated with Refractory Acute Disseminated Encephalomyelitis. ( 27239186 )
2016
13
Recurrent acute disseminated encephalomyelitis: A favorable outcome among recurrent brain diseases in pediatric patient. ( 27857797 )
2016
14
Acute Disseminated Encephalomyelitis. ( 27253358 )
2016
15
Acute disseminated encephalomyelitis following Campylobacter jejuni gastroenteritis: Case report and review of the literature. ( 27888275 )
2016
16
Acute Disseminated Encephalomyelitis After Human Parechovirus Infection. ( 26741581 )
2016
17
Acute Disseminated Encephalomyelitis. ( 27322219 )
2016
18
Acute Disseminated Encephalomyelitis after Oral Therapy with Herbal Extracts: A Case Report. ( 27308086 )
2016
19
Acute Disseminated Encephalomyelitis in an Incarcerated Adolescent Presents as Acute Psychosis: Case Report and Literature Review. ( 27749808 )
2016
20
Acute disseminated encephalomyelitis in children. ( 27841185 )
2016
21
Acute disseminated encephalomyelitis: A clinical and neuroradiological profile of pediatric patients. ( 27841184 )
2016
22
An Acute Disseminated Encephalomyelitis-Like Illness in the Elderly: Neuroimaging and Neuropathology Findings. ( 27896893 )
2016
23
Two Cases of Acute Disseminated Encephalomyelitis Following Vaccination Against Human Papilloma Virus. ( 27803416 )
2016
24
Acute Disseminated Encephalomyelitis After Influenza Vaccination: A Case Report. ( 27252106 )
2016
25
Posttraumatic Acute Disseminated Encephalomyelitis in a Child Resolved by Steroid Therapy: Case Report. ( 26833988 )
2016
26
ADHD as Sequel to Acute Disseminated Encephalomyelitis. ( 27053911 )
2016
27
Treatment of hemorrhagic acute disseminated encephalomyelitis with cyclophosphamide. ( 26843496 )
2016
28
Acute Disseminated Encephalomyelitis. ( 27253359 )
2016
29
Dopa-responsive acute disseminated encephalomyelitis with marked atrophy of the striate body. ( 27256998 )
2016
30
Diagnosis and therapy of acute disseminated encephalomyelitis and its variants. ( 26620160 )
2016
31
Long-Term Neurocognitive, Psychosocial, and Magnetic Resonance Imaging Outcomes in Pediatric-Onset Acute Disseminated Encephalomyelitis. ( 26996404 )
2016
32
Acute disseminated encephalomyelitis in a case of autoimmune haemolytic anaemia: a rare association. ( 27268491 )
2016
33
Evolution of MRI abnormalities in paediatric acute disseminated encephalomyelitis. ( 27670632 )
2016
34
Acute disseminated encephalomyelitis: Updates on an inflammatory CNS syndrome. ( 27572859 )
2016
35
Atypical global Takotsubo syndrome in a patient with acute disseminated encephalomyelitis. ( 26992710 )
2016
36
Acute disseminated encephalomyelitis presenting as a brainstem encephalitis. ( 26903073 )
2016
37
An Adult Case of Anti-Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Multiphasic Acute Disseminated Encephalomyelitis at 33-year Intervals. ( 26984094 )
2016
38
An atypical case of acute disseminated encephalomyelitis associated with cytomegalovirus infection. ( 26856946 )
2016
39
Long-term motor, cognitive and behavioral outcome of acute disseminated encephalomyelitis. ( 26876769 )
2016
40
Pattern and Outcome of Acute Disseminated Encephalomyelitis (ADEM) in Children: Experience in a Tertiary Center, Upper Egypt. ( 27648197 )
2016
41
Cardiogenic shock from atypical Takotsubo cardiomyopathy attributed to acute disseminated encephalomyelitis lesion involving the medulla. ( 26868678 )
2016
42
Acute disseminated encephalomyelitis following Plasmodium vivax malaria. ( 27727782 )
2016
43
Clinical Profiles and Short-Term Outcomes of Acute Disseminated Encephalomyelitis in Adult Chinese Patients. ( 27449911 )
2016
44
A case of paroxysmal sympathetic storm after acute disseminated encephalomyelitis and hypoxic encephalopathy responding to clonidine hydrochloride. ( 26754594 )
2016
45
Acute Disseminated Encephalomyelitis Following Immunization with Human Papillomavirus Vaccines. ( 27803397 )
2016
46
Acute disseminated encephalomyelitis: current knowledge and open questions. ( 26037112 )
2015
47
Acute disseminated encephalomyelitis following inactivated influenza vaccination in the Brazilian Amazon: a case report. ( 26312942 )
2015
48
Acute disseminated encephalomyelitis following influenza vaccination. ( 25904259 )
2015
49
Multiphasic acute disseminated encephalomyelitis associated with atypical rubella virus infection. ( 25662343 )
2015
50
Simultaneous presentation of acute disseminated encephalomyelitis (ADEM) and systemic lupus erythematosus (SLE) after enteroviral infection: can ADEM present as the first manifestation of SLE? ( 25488421 )
2015

Variations for Acute Disseminated Encephalomyelitis

Expression for Acute Disseminated Encephalomyelitis

Search GEO for disease gene expression data for Acute Disseminated Encephalomyelitis.

Pathways for Acute Disseminated Encephalomyelitis

Pathways related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

(show all 28)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.12 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1 IL10 IL1B
2
Show member pathways
12.77 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1
3
Show member pathways
12.6 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1 IL1B
4
Show member pathways
12.54 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1 IL10 IL1B
5
Show member pathways
12.44 HLA-DQA1 HLA-DQB1 HLA-DRB1 IL10
6
Show member pathways
12.37 HLA-DQA1 HLA-DQB1 HLA-DRB1 IL10 IL1B
7
Show member pathways
12.35 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1
8 12.23 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1
9
Show member pathways
12.18 HLA-DQA1 HLA-DQB1 HLA-DRB1
10
Show member pathways
12.14 HLA-DQA1 HLA-DQB1 HLA-DRB1
11
Show member pathways
12.01 HLA-DQA1 HLA-DQB1 HLA-DRB1
12
Show member pathways
11.98 HLA-B IL10 IL1B
13 11.98 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1
14 11.96 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1 IL10
15 11.94 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1
16
Show member pathways
11.79 HLA-DQA1 HLA-DQB1 HLA-DRB1
17 11.76 HLA-DQA1 HLA-DQB1 HLA-DRB1
18
Show member pathways
11.74 HLA-DQA1 HLA-DQB1 HLA-DRB1
19 11.69 HLA-DQA1 HLA-DQB1 HLA-DRB1 IL1B
20
Show member pathways
11.63 HLA-DQA1 HLA-DQB1 HLA-DRB1 IL10 IL1B
21 11.62 HLA-DQA1 HLA-DQB1 HLA-DRB1 IL1B
22 11.57 HLA-DQA1 HLA-DQB1 HLA-DRB1
23 11.27 HLA-DQA1 HLA-DQB1 HLA-DRB1 IL10 IL1B
24 11.2 HLA-B IL1B
25 11.2 HLA-DQA1 HLA-DQB1 HLA-DRB1 IL10
26 11.17 IL10 IL1B
27 11.16 IL10 IL1B
28 11.11 HLA-DRB1 IL10 IL1B

GO Terms for Acute Disseminated Encephalomyelitis

Cellular components related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 Golgi membrane GO:0000139 9.73 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1
2 endosome membrane GO:0010008 9.63 HLA-DQA1 HLA-DQB1 HLA-DRB1
3 trans-Golgi network membrane GO:0032588 9.58 HLA-DQA1 HLA-DQB1 HLA-DRB1
4 endocytic vesicle membrane GO:0030666 9.54 HLA-DQA1 HLA-DQB1 HLA-DRB1
5 transport vesicle membrane GO:0030658 9.5 HLA-DQA1 HLA-DQB1 HLA-DRB1
6 clathrin-coated endocytic vesicle membrane GO:0030669 9.43 HLA-DQA1 HLA-DQB1 HLA-DRB1
7 MHC class II protein complex GO:0042613 9.33 HLA-DQA1 HLA-DQB1 HLA-DRB1
8 ER to Golgi transport vesicle membrane GO:0012507 9.26 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1
9 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 8.92 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1

Biological processes related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 T cell receptor signaling pathway GO:0050852 9.67 HLA-DQA1 HLA-DQB1 HLA-DRB1
2 antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 9.61 HLA-DQA1 HLA-DQB1 HLA-DRB1
3 T cell costimulation GO:0031295 9.58 HLA-DQA1 HLA-DQB1 HLA-DRB1
4 negative regulation of T cell proliferation GO:0042130 9.54 HLA-DRB1 IL10
5 negative regulation of interferon-gamma production GO:0032689 9.52 HLA-DRB1 IL10
6 positive regulation of interleukin-6 secretion GO:2000778 9.51 IL1B MBP
7 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.48 IL10 IL1B
8 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.46 IL10 MBP
9 interferon-gamma-mediated signaling pathway GO:0060333 9.46 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1
10 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 9.43 HLA-DQA1 HLA-DQB1 HLA-DRB1
11 humoral immune response mediated by circulating immunoglobulin GO:0002455 9.37 HLA-DQB1 HLA-DRB1
12 immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 9.32 HLA-DQB1 HLA-DRB1
13 antigen processing and presentation GO:0019882 9.26 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1
14 immune response GO:0006955 9.17 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1 IL10 IL1B

Molecular functions related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 MHC class II receptor activity GO:0032395 9.13 HLA-DQA1 HLA-DQB1 HLA-DRB1
2 peptide antigen binding GO:0042605 8.92 HLA-B HLA-DQA1 HLA-DQB1 HLA-DRB1

Sources for Acute Disseminated Encephalomyelitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....