MCID: ACT049
MIFTS: 50

Acute Disseminated Encephalomyelitis malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Acute Disseminated Encephalomyelitis

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Sources:
11Disease Ontology, 46NIH Rare Diseases, 47NINDS, 13DISEASES, 52Orphanet, 66UMLS, 48Novoseek, 37MeSH, 43NCIt, 29ICD10 via Orphanet, 28ICD10, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Acute Disseminated Encephalomyelitis:

Name: Acute Disseminated Encephalomyelitis 11 46 47 13 52
Acute Disseminated Encephalitis 11 52 66
Adem 11 46 52
 
Encephalomyelitis, Acute Disseminated 66
Encephalomyelitis Acute Disseminated 48
Ade 46

Characteristics:

Orphanet epidemiological data:

52
acute disseminated encephalomyelitis:
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe); Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

Disease Ontology11 DOID:639
MeSH37 D004673
NCIt43 C34578
SNOMED-CT60 83942000
Orphanet52 ORPHA83597
ICD10 via Orphanet29 G04.0
ICD1028 G04.0

Summaries for Acute Disseminated Encephalomyelitis

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NIH Rare Diseases:46 Acute disseminated encephalomyelitis (adem) is a neurological condition characterized by a brief but intense attack of inflammation in the brain and spinal cord. this may lead to damage of the layer of insulation around affected the nerves (myelin) within affected areas. adem often follows viral infection, or less often, vaccinations for measles, mumps, or rubella (mmr). symptoms usually appear rapidly, beginning with fever, fatigue, headache, nausea and vomiting. treatment for adem is targeted at suppressing inflammation in the brain using anti-inflammatory drugs.  last updated: 8/16/2016

MalaCards based summary: Acute Disseminated Encephalomyelitis, also known as acute disseminated encephalitis, is related to common variable immunodeficiency and measles, and has symptoms including diffuse inflammation An important gene associated with Acute Disseminated Encephalomyelitis is MOG (Myelin Oligodendrocyte Glycoprotein), and among its related pathways are Cytokines and Inflammatory Response and Immune response Antigen presentation by MHC class II. Affiliated tissues include brain, spinal cord and brain, and related mouse phenotypes are hematopoietic system and immune system.

Disease Ontology:11 An encephalomyelitis characterized by inflammation located in brain and located in spinal cord that damages myelin. it usually occurs after viral infection, but also following vaccination, bacterial or parasitic infection.

NINDS:47 Acute disseminated encephalomyelitis (ADEM) is characterized by a brief but widespread attack of inflammation in the brain and spinal cord that damages myelin ? the protective covering of nerve fibers.

Wikipedia:69 Acute disseminated encephalomyelitis (ADEM), or acute demyelinating encephalomyelitis, is a rare... more...

Related Diseases for Acute Disseminated Encephalomyelitis

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Diseases related to Acute Disseminated Encephalomyelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 262)
idRelated DiseaseScoreTop Affiliating Genes
1common variable immunodeficiency30.3HLA-B, HLA-DRB1
2measles30.2AQP4, HLA-DQB1
3myelitis29.6AQP4, MBP, MOG
4systemic lupus erythematosus29.5HLA-DQA1, HLA-DQB1, HLA-DRB1, IL10
5immunodeficiency 27b, mycobacteriosis, ad12.0
6renal tubular acidosis, distal, ad11.9
7keratosis palmoplantaris striata i, ad11.9
8emery-dreifuss muscular dystrophy 2, ad11.9
9emery-dreifuss muscular dystrophy 7, ad11.9
10epidermolysis bullosa dystrophica, ad11.9
11cutis laxa, ad11.9
12slowed nerve conduction velocity, ad11.9
13spinal muscular atrophy, lower extremity-predominant, 2, ad11.9
14familial mediterranean fever, ad11.9
15spinal muscular atrophy, lower extremity-predominant 1, ad11.8
16dopa-responsive dystonia; segawa syndrome ad11.8
17alzheimer disease11.7
18hyper-ige recurrent infection syndrome11.6
19myopathy, centronuclear11.3
20post-vaccinal encephalitis11.2
21alzheimer disease-410.8
22ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant10.8
23hypocalcemia, autosomal dominant10.8
24alzheimer disease, type 310.8
25alzheimer disease-210.8
26dnm2-related intermediate charcot-marie-tooth neuropathy10.8
27tmem43-related emery-dreifuss muscular dystrophy, autosomal10.8
28alzheimer disease type 110.8
29autosomal dominant proximal renal tubular acidosis10.8
30alzheimer disease mitochondrial10.8
31hyperlipidemia type 310.8
32transverse myelitis10.7
33osteogenesis imperfecta congenita, microcephaly, and cataracts10.7HLA-DQA1, HLA-DQB1
34fruit allergy10.6HLA-DQB1, HLA-DRB1
35quinquaud's decalvans folliculitis10.6HLA-DQB1, HLA-DRB1
36pediatric systemic lupus erythematosus10.6HLA-DQB1, HLA-DRB1
37krieble bixler syndrome10.6HLA-DQB1, HLA-DRB1
38limb dystonia10.6HLA-DQB1, HLA-DRB1
39spondylarthropathy10.6HLA-DQB1, HLA-DRB1
40rheumatic myocarditis10.6HLA-DQB1, HLA-DRB1
41nebulin-related early-onset distal myopathy10.6HLA-DQB1, HLA-DRB1
42purpura fulminans10.6HLA-DQB1, HLA-DRB1
43lymphocytic colitis10.6HLA-DQB1, HLA-DRB1
44thrombocytopenia due to platelet alloimmunization10.6HLA-DQB1, HLA-DRB1
45ampulla of vater neoplasm10.5HLA-DQA1, HLA-DQB1
46mononeuritis of upper limb10.5HLA-DQB1, HLA-DRB1
47juvenile dermatitis herpetiformis10.5HLA-DQA1, HLA-DQB1
48multifocal choroiditis10.5HLA-DRB1, MOG
49hypoxia10.5HLA-DQB1, HLA-DRB1
50atopic dermatitis10.4

Graphical network of the top 20 diseases related to Acute Disseminated Encephalomyelitis:



Diseases related to acute disseminated encephalomyelitis

Symptoms for Acute Disseminated Encephalomyelitis

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UMLS symptoms related to Acute Disseminated Encephalomyelitis:


diffuse inflammation

Drugs & Therapeutics for Acute Disseminated Encephalomyelitis

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Drugs for Acute Disseminated Encephalomyelitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1PREDNISOLONE ACETATEPhase 31118
2
PrednisolonePhase 3111850-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
3
MethylprednisolonePhase 3111883-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
4glucocorticoidsPhase 34756

Interventional clinical trials:

idNameStatusNCT IDPhase
16-year Antibody Check After Third Vaccination Against Japanese EncephalitisCompletedNCT02039440Phase 4
2Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous MethylprednisoloneActive, not recruitingNCT00004645Phase 3
3Centralized Reading Assessment of Chronic CerebroSpinal Venous Insufficiency (CCSVI) in Patients With Multiple Sclerosis and Other Neurological DiseasesCompletedNCT02308579
4Biobank For MS And Other Demyelinating DiseasesActive, not recruitingNCT00445367

Search NIH Clinical Center for Acute Disseminated Encephalomyelitis

Genetic Tests for Acute Disseminated Encephalomyelitis

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Anatomical Context for Acute Disseminated Encephalomyelitis

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MalaCards organs/tissues related to Acute Disseminated Encephalomyelitis:

34
Brain, Spinal cord, T cells, Bone, Bone marrow, Lung, Myeloid

FMA organs/tissues related to Acute Disseminated Encephalomyelitis:

17
Brain, Spinal cord

Animal Models for Acute Disseminated Encephalomyelitis or affiliated genes

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MGI Mouse Phenotypes related to Acute Disseminated Encephalomyelitis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.2AQP4, HLA-DQA1, HLA-DQB1, IL10, MBP, MOG
2MP:00053877.1AQP4, HLA-DQA1, HLA-DQB1, IL10, MBP, MOG

Publications for Acute Disseminated Encephalomyelitis

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Articles related to Acute Disseminated Encephalomyelitis:

(show top 50)    (show all 580)
idTitleAuthorsYear
1
A case of paroxysmal sympathetic storm after acute disseminated encephalomyelitis and hypoxic encephalopathy responding to clonidine hydrochloride. (26754594)
2016
2
Acute Disseminated Encephalomyelitis after Oral Therapy with Herbal Extracts: A Case Report. (27308086)
2016
3
Acute disseminated encephalomyelitis: the time until diagnosis and its subsequent course in children. (23143724)
2014
4
Acute disseminated encephalomyelitis: an uncommon presentation of hyper IgE syndrome. (25518794)
2014
5
Early rehabilitative treatment for pediatric acute disseminated encephalomyelitis: case report. (24937355)
2014
6
Acute Disseminated Encephalomyelitis Mimicking Leukodystrophy. (25238667)
2014
7
A case of acute disseminated encephalomyelitis following influenza virus A-H1N1 infection. (24056381)
2013
8
Can "dissemination" include the PNS in adults with acute disseminated encephalomyelitis? (23325898)
2013
9
Co-morbid Guillain-BarrAc syndrome and acute disseminated encephalomyelitis. (23545617)
2013
10
Acute disseminated encephalomyelitis, transverse myelitis, and neuromyelitis optica. (23917095)
2013
11
Acute disseminated encephalomyelitis onset: evaluation based on vaccine adverse events reporting systems. (24147076)
2013
12
Acute disseminated encephalomyelitis. (22914374)
2012
13
Acute disseminated encephalomyelitis--a prospective study of clinical profile and in-hospital outcome predictors. (22799110)
2012
14
Multiphasic acute disseminated encephalomyelitis (ADEM) following influenza type A (swine specific H1N1). (21997495)
2012
15
Acute disseminated encephalomyelitis presenting as pyrexia of unknown origin. (23248701)
2012
16
Severe acute disseminated encephalomyelitis: a paediatric intensive care population-based study. (20876155)
2011
17
Bithalamic compromise in acute disseminated encephalomyelitis following H1N1 influenza vaccine. (21755147)
2011
18
Chronic sequelae of acute disseminated encephalomyelitis in a child. (20869688)
2010
19
Partial KlA1ver-Bucy syndrome in a patient with acute disseminated encephalomyelitis. (20638284)
2010
20
Relapsing acute disseminated encephalomyelitis in children: further evaluation of the diagnosis. (20823029)
2010
21
Descriptive study of acute disseminated encephalomyelitis and evaluation of functional outcome predictors. (20393243)
2010
22
Acute disseminated encephalomyelitis associated with meningitis due to Mycobacterium intracellulare. (20930438)
2010
23
Cerebellar mutism in pediatric acute disseminated encephalomyelitis. (20837316)
2010
24
Predicting the motor outcome of acute disseminated encephalomyelitis by apparent diffusion coefficient imaging: Two case reports. (19269652)
2009
25
Acute disseminated encephalomyelitis: postinfectious, postimmunization and variant forms. (19769447)
2009
26
Acute disseminated encephalomyelitis-like manifestations in a patient with neuro-BehAset disease. (19741436)
2009
27
Neurocutaneous melanosis with acute disseminated encephalomyelitis. (17103186)
2007
28
Recurrent acute disseminated encephalomyelitis. (17351306)
2007
29
Acute disseminated encephalomyelitis in North Indian children: clinical profile and follow-up. (17005100)
2006
30
The follow-up of acute disseminated encephalomyelitis in a comatose pregnant woman. (16099583)
2006
31
Tracing immature myelin in acute disseminated encephalomyelitis. (17172061)
2006
32
Central brain herniation secondary to fulminant acute disseminated encephalomyelitis: implications for neurosurgical management. Case report. (16961146)
2006
33
Acute disseminated encephalomyelitis after liver transplantation. (15824267)
2005
34
Acute disseminated encephalomyelitis: an update. (16286539)
2005
35
Acute disseminated encephalomyelitis associated with enteroviral infection. (15626964)
2004
36
Acute disseminated encephalomyelitis. (12566545)
2003
37
Acute disseminated encephalomyelitis. (12391446)
2002
38
Effectiveness of intravenous immunoglobulin treatment in adult patients with steroid-resistant monophasic or recurrent acute disseminated encephalomyelitis. (11954856)
2002
39
Increased peripheral blood interferon gamma-producing T cells in acute disseminated encephalomyelitis. (11063842)
2000
40
Intravenous immunoglobulin therapy in acute disseminated encephalomyelitis. (10465150)
1999
41
Acute disseminated encephalomyelitis associated with tetanus vaccination. (10343155)
1999
42
Acute disseminated encephalomyelitis: clinical and MRI study from South India. (10450798)
1999
43
Acute disseminated encephalomyelitis after accidental injection of a hog vaccine: successful treatment with plasmapheresis. (9868420)
1998
44
Early high-dose intravenous methylprednisolone in acute disseminated encephalomyelitis: a successful recovery. (9339706)
1997
45
Intravenous gammaglobulin therapy in recurrent acute disseminated encephalomyelitis. (8780119)
1996
46
Acute disseminated encephalomyelitis probably related to a Mycoplasma pneumoniae infection. (8453818)
1993
47
Acute disseminated encephalomyelitis following HTLV-I associated myelopathy. (1506865)
1992
48
Cell-mediated immunity to myelin basic protein in acute disseminated encephalomyelitis. (4133960)
1974
49
Effect of nutrition on the production of acute disseminated encephalomyelitis in mice. (13416471)
1957
50
Studies on acute disseminated encephalomyelitis produced experimentally in rhesus monkeys. (14832406)
1951

Variations for Acute Disseminated Encephalomyelitis

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Expression for genes affiliated with Acute Disseminated Encephalomyelitis

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Search GEO for disease gene expression data for Acute Disseminated Encephalomyelitis.

Pathways for genes affiliated with Acute Disseminated Encephalomyelitis

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Pathways related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

(show all 22)
idSuper pathwaysScoreTop Affiliating Genes
19.7HLA-DRB1, IL10
2
Show member pathways
9.2HLA-DQA1, HLA-DQB1, HLA-DRB1
3
Show member pathways
9.2HLA-DQA1, HLA-DQB1, HLA-DRB1
49.2HLA-DQA1, HLA-DQB1, HLA-DRB1
5
Show member pathways
9.2HLA-DQA1, HLA-DQB1, HLA-DRB1
6
Show member pathways
9.2HLA-DQA1, HLA-DQB1, HLA-DRB1
79.2HLA-DQA1, HLA-DQB1, HLA-DRB1
8
Show member pathways
9.2HLA-DQA1, HLA-DQB1, HLA-DRB1
99.2HLA-DQA1, HLA-DQB1, HLA-DRB1
109.2HLA-DQA1, HLA-DQB1, HLA-DRB1
118.9HLA-DQA1, HLA-DQB1, HLA-DRB1, IL10
128.9HLA-DQA1, HLA-DQB1, HLA-DRB1, IL10
13
Show member pathways
8.9HLA-DQA1, HLA-DQB1, HLA-DRB1, IL10
14
Show member pathways
8.9HLA-DQA1, HLA-DQB1, HLA-DRB1, IL10
15
Show member pathways
8.6HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
168.6HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
178.6HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
18
Show member pathways
8.6HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
19
Show member pathways
8.6HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
208.3HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1, IL10
21
Show member pathways
8.3HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1, IL10
228.1HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1, MPZ

GO Terms for genes affiliated with Acute Disseminated Encephalomyelitis

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Cellular components related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:00426139.9HLA-DQA1, HLA-DQB1, HLA-DRB1
2clathrin-coated endocytic vesicle membraneGO:00306699.8HLA-DQA1, HLA-DQB1, HLA-DRB1
3trans-Golgi network membraneGO:00325889.8HLA-DQA1, HLA-DQB1, HLA-DRB1
4transport vesicle membraneGO:00306589.8HLA-DQA1, HLA-DQB1, HLA-DRB1
5endocytic vesicle membraneGO:00306669.7HLA-DQA1, HLA-DQB1, HLA-DRB1
6myelin sheathGO:00432099.3MBP, MOG, MPZ
7integral component of lumenal side of endoplasmic reticulum membraneGO:00715569.3HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
8lysosomal membraneGO:00057659.2HLA-DQA1, HLA-DQB1, HLA-DRB1
9ER to Golgi transport vesicle membraneGO:00125079.2HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
10Golgi membraneGO:00001399.0HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
11plasma membraneGO:00058866.4AQP4, HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1, MBP

Biological processes related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1T cell receptor signaling pathwayGO:00508529.5HLA-DQA1, HLA-DQB1, HLA-DRB1
2antigen processing and presentation of exogenous peptide antigen via MHC class IIGO:00198869.3HLA-DQA1, HLA-DQB1, HLA-DRB1
3agingGO:00075689.2IL10, MBP, MOG
4interferon-gamma-mediated signaling pathwayGO:00603339.1HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
5T cell costimulationGO:00312958.9HLA-DQA1, HLA-DQB1, HLA-DRB1
6immune responseGO:00069558.8HLA-DQA1, HLA-DQB1, IL10, MBP

Molecular functions related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II receptor activityGO:003239510.0HLA-DQA1, HLA-DQB1
2peptide antigen bindingGO:00426058.6HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1

Sources for Acute Disseminated Encephalomyelitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet