MCID: ACT049
MIFTS: 47

Acute Disseminated Encephalomyelitis malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Acute Disseminated Encephalomyelitis

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 46NINDS, 12DISEASES, 51Orphanet, 65UMLS, 47Novoseek, 36MeSH, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 27ICD10
See all MalaCards sources

Aliases & Descriptions for Acute Disseminated Encephalomyelitis:

Name: Acute Disseminated Encephalomyelitis 10 45 46 12 51
Acute Disseminated Encephalitis 10 51 65
Adem 10 45 51
 
Encephalomyelitis, Acute Disseminated 65
Encephalomyelitis Acute Disseminated 47
Ade 45

Characteristics:

Orphanet epidemiological data:

51
acute disseminated encephalomyelitis:
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe); Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

Disease Ontology10 DOID:639
MeSH36 D004673
NCIt42 C34578
SNOMED-CT59 83942000
Orphanet51 83597
ICD10 via Orphanet28 G04.0
ICD1027 G04.0
UMLS65 C0014059, C3536864

Summaries for Acute Disseminated Encephalomyelitis

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NIH Rare Diseases:45 Acute disseminated encephalomyelitis (adem) is a neurological condition characterized by a brief but intense attack of inflammation in the brain and spinal cord that damages myelin – the protective covering of nerve fibers.  it often follows viral infection, or less often, vaccination for measles, mumps, or rubella. treatment for adem is targeted at suppressing inflammation in the brain using anti-inflammatory drugs. plasmapheresis or intravenous immunoglobulin therapy may also be used.  additional treatment is symptomatic and supportive.  last updated: 10/31/2011

MalaCards based summary: Acute Disseminated Encephalomyelitis, also known as acute disseminated encephalitis, is related to postinfectious encephalomyelitis and subcorneal pustular dermatosis. An important gene associated with Acute Disseminated Encephalomyelitis is MBP (Myelin Basic Protein), and among its related pathways are Tuberculosis and Immune response Antigen presentation by MHC class II. Affiliated tissues include brain, spinal cord and brain, and related mouse phenotype hematopoietic system.

Disease Ontology:10 An encephalomyelitis characterized by inflammation located in brain and located in spinal cord that damages myelin. It usually occurs after viral infection, but also following vaccination, bacterial or parasitic infection.

NINDS:46 Acute disseminated encephalomyelitis (ADEM) is characterized by a brief but widespread attack of inflammation in the brain and spinal cord that damages myelin ? the protective covering of nerve fibers.

Wikipedia:68 Acute disseminated encephalomyelitis (ADEM), or acute demyelinating encephalomyelitis, is a rare... more...

Related Diseases for Acute Disseminated Encephalomyelitis

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Diseases related to Acute Disseminated Encephalomyelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 454)
idRelated DiseaseScoreTop Affiliating Genes
1postinfectious encephalomyelitis31.4HLA-B, HLA-DRB1
2subcorneal pustular dermatosis30.7HLA-B, HLA-DQB1
3bullous pemphigoid30.2HLA-DQA1, HLA-DQB1
4psoriasis30.2HLA-B, HLA-DQB1, HLA-DRB1
5fatty liver disease30.1HLA-B, HLA-DQB1
6atopic dermatitis30.0AQP4, HCRT, MBP, MOG
7rheumatoid arthritis29.7HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
8immunodeficiency 27b, mycobacteriosis, ad12.4
9renal tubular acidosis, distal, ad12.3
10keratosis palmoplantaris striata i, ad12.3
11emery-dreifuss muscular dystrophy 2, ad12.3
12emery-dreifuss muscular dystrophy 7, ad12.3
13epidermolysis bullosa dystrophica, ad12.3
14cutis laxa, ad12.3
15slowed nerve conduction velocity, ad12.3
16spinal muscular atrophy, lower extremity-predominant, 2, ad12.3
17familial mediterranean fever, ad12.3
18spinal muscular atrophy, lower extremity-predominant 1, ad12.2
19hyper-ige recurrent infection syndrome12.0
20alzheimer disease11.9
21myopathy, centronuclear11.7
22post-vaccinal encephalitis11.6
23alzheimer disease-211.6
24alzheimer disease-411.2
25ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant11.2
26hypocalcemia, autosomal dominant11.2
27alzheimer disease, type 311.2
28alzheimer disease type 111.2
29dnm2-related intermediate charcot-marie-tooth neuropathy11.2
30tmem43-related emery-dreifuss muscular dystrophy, autosomal11.2
31autosomal dominant proximal renal tubular acidosis11.2
32alzheimer disease mitochondrial11.2
33hyperlipidemia type 311.2
34acute hemorrhagic leukoencephalitis10.7
35fructose intolerance10.6
36transverse myelitis10.6
37immune-mediated encephalomyelitis10.6
38early-onset, autosomal dominant alzheimer disease10.5
39endotheliitis10.4
40immunodeficiency 31a, mycobacteriosis, autosomal dominant10.4
41hepatitis10.4
42leukemia10.4
43lichen planus pemphigoides10.4HLA-DQB1, HLA-DRB1
44heavy chain deposition disease10.4HLA-DQB1, HLA-DRB1
45autoimmune polyglandular syndrome type 210.4HLA-DQB1, HLA-DRB1
46best1 retinopathy10.4HLA-DQB1, HLA-DRB1
47non-distal monosomy 10q10.4HLA-DQB1, HLA-DRB1
48lichtenstein syndrome10.4HLA-DQB1, HLA-DRB1
49red cell phospholipid defect with hemolysis10.4HLA-DQB1, HLA-DRB1
50pediatric t-cell leukemia10.4HLA-DRB1, MOG

Graphical network of the top 20 diseases related to Acute Disseminated Encephalomyelitis:



Diseases related to acute disseminated encephalomyelitis

Symptoms for Acute Disseminated Encephalomyelitis

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Drugs & Therapeutics for Acute Disseminated Encephalomyelitis

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Drugs for Acute Disseminated Encephalomyelitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1VaccinesPhase 46085
2ImmunoglobulinsPhase 44477
3AntibodiesPhase 44477
4
PrednisoloneapprovedPhase 3108250-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
Flo-pred
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
MLS001304083
 
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
Millipred
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Omnipred
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
5
MethylprednisoloneapprovedPhase 3108283-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
A-methapred
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Depo-medrol
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Solu-medrol
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
6Prednisolone hemisuccinatePhase 31082
7Prednisolone phosphatePhase 31082
8Methylprednisolone HemisuccinatePhase 31082
9Prednisolone acetatePhase 31082
10Methylprednisolone acetatePhase 31082
11Antibodies, Antiphospholipid25

Interventional clinical trials:

idNameStatusNCT IDPhase
16-year Antibody Check After Third Vaccination Against Japanese EncephalitisCompletedNCT02039440Phase 4
2Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous MethylprednisoloneActive, not recruitingNCT00004645Phase 3
3Centralized Reading Assessment of Chronic CerebroSpinal Venous Insufficiency (CCSVI) in Patients With Multiple Sclerosis and Other Neurological DiseasesCompletedNCT02308579
4Biobank For MS And Other Demyelinating DiseasesActive, not recruitingNCT00445367

Search NIH Clinical Center for Acute Disseminated Encephalomyelitis

Genetic Tests for Acute Disseminated Encephalomyelitis

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Anatomical Context for Acute Disseminated Encephalomyelitis

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MalaCards organs/tissues related to Acute Disseminated Encephalomyelitis:

33
Brain, Spinal cord, Breast, Prostate, T cells, Lung, Heart

FMA organs/tissues related to Acute Disseminated Encephalomyelitis:

16
Brain, Spinal cord

Animal Models for Acute Disseminated Encephalomyelitis or affiliated genes

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MGI Mouse Phenotypes related to Acute Disseminated Encephalomyelitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.4AQP4, HLA-DQA1, HLA-DQB1, MBP, MOG, MPZ

Publications for Acute Disseminated Encephalomyelitis

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Articles related to Acute Disseminated Encephalomyelitis:

(show top 50)    (show all 549)
idTitleAuthorsYear
1
Limited value of pro-inflammatory oxylipins and cytokines as circulating biomarkers in endometriosis - a targeted 'omics study. (27193963)
2016
2
Monozygotic twins presenting with isolated sagittal and bicoronal synostosis, respectively. (26925815)
2016
3
Developmental dyslexia: predicting individual risk. (25832320)
2015
4
Morbid obesity attenuates the skeletal abnormalities associated with leptin deficiency in mice. (24990938)
2014
5
Correction: Soluble Expression of Human Leukemia Inhibitory Factor with Protein Disulfide Isomerase in Escherichia coli and Its Simple Purification. (24400060)
2014
6
Contribution of Bcl-2 phosphorylation to Bak binding and drug resistance. (24097825)
2013
7
Rapidly fatal community-acquired pneumonia due to Klebsiella pneumoniae complicated with acute myocarditis and accelerated idioventricular rhythm. (22153763)
2012
8
Symptom Dimensions in Two Samples of Africans Americans with Obsessive-Compulsive Disorder. (22708117)
2012
9
Female epispadias. (22005369)
2011
10
Phosphorylation of I^-catenin results in lack of I^-catenin signaling in melanoma. (21584489)
2011
11
Prolonged inactivity up-regulates cholesteryl ester transfer protein independently of body fat changes in humans. (20228163)
2010
12
Berberine suppresses neuroinflammatory responses through AMP-activated protein kinase activation in BV-2 microglia. (20512929)
2010
13
Fibroblast growth factor 19 serum levels: relation to renal function and metabolic parameters. (20013647)
2010
14
The level and compartmentalization of phosphatidate phosphatase-1 (lipin-1) control the assembly and secretion of hepatic VLDL. (18769019)
2009
15
The class I bHLH factors E2-2A and E2-2B regulate EMT. (19295128)
2009
16
Neuroimaging findings of Sturge-Weber Syndrome in a child with Tuberous Sclerosis. (18644690)
2009
17
Immunohistochemical localization of interleukin-6 in human pancreatitis. (18091322)
2008
18
Pyridoxal 5'-phosphate values in cerebrospinal fluid: reference values and diagnosis of PNPO deficiency in paediatric patients. (18294893)
2008
19
Otitis externa: the analysis of relationship between particular signs/symptoms and species and genera of identified microorganisms. (18664104)
2008
20
Modern bariatric surgery and nephrolithiasis--are we on the verge of a new epidemic? (18076950)
2008
21
Synthesis, X-ray crystal structures and biomimetic and anticancer activities of novel copper(II)benzoate complexes incorporating 2-(4'-thiazolyl)benzimidazole (thiabendazole), 2-(2-pyridyl)benzimidazole and 1,10-phenanthroline as chelating nitrogen donor ligands. (17397929)
2007
22
The analysis for mRNA mutation of MLH1, MSH2 genes and the gene diagnosis for hereditary nonpolyposis colorectal cancer]. (16456782)
2006
23
Influence of acute serotonin reuptake inhibition on colonic sensorimotor function in man. (16393306)
2006
24
Ethnic differences in the distribution of CYP3A5 gene polymorphisms. (17162466)
2006
25
Failure of physiologic doses of pure UVA or UVB to induce lesions in photosensitive cutaneous lupus erythematosus: implications for phototesting. (17100736)
2006
26
Relationship between the proliferation and immunoinduction of epithelial cells and the destruction of hair follicles and sebaceous glands in keloids]. (16736611)
2006
27
Effect of arginine loss in myelin basic protein, as occurs in its deiminated charge isoform, on mediation of actin polymerization and actin binding to a lipid membrane in vitro. (15736962)
2005
28
Plasma adiponectin levels and sonographic phenotypes of subclinical carotid artery atherosclerosis: data from the SAPHIR Study. (16282542)
2005
29
MLL translocations with concurrent 3' deletions: interpretation of FISH results. (15334550)
2004
30
DNA microarray analysis of vitamin D-induced gene expression in a human colon carcinoma cell line. (14996990)
2004
31
37-kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake. (12615923)
2003
32
Mitochondrial complex I inhibition produces selective damage to hippocampal subfield CA1 in organotypic slice cultures. (14715437)
2003
33
Effects of rhein on human articular chondrocytes in alginate beads. (12527330)
2003
34
Regulation of the Neurospora circadian clock by casein kinase II. (11959847)
2002
35
Pharmacology and clinical experience with fedotozine. (11116283)
2001
36
Human onchocerciasis in the Amazonian area of southern Venezuela: spatial and temporal variations in biting and parity rates of black fly (Diptera: Simuliidae) vectors. (11476332)
2001
37
Comparative study of three common G6PD gene mutations in Yao and Han People in Guangxi]. (11876979)
2000
38
Diversity of glutamate transporter expression and function in the mammalian retina. (11026473)
2000
39
Ciprofloxacin for treatment of tularemia in children. (10819342)
2000
40
Calcium depletion dissociates and activates heterodimeric notch receptors. (10669757)
2000
41
Identification of residues in the Gla-domain of human factor IX involved in the binding to conformation specific antibodies. (9507074)
1998
42
Painful ophthalmoplegia caused by idiopathic hypertrophic cranial pachymeningitis in the cavernous sinus. (18639052)
1998
43
Serological evidence of human granulocytic ehrlichiosis in Switzerland. (9665305)
1998
44
Coordinated effects of electromagnetic field exposure on erythropoietin-induced activities of phosphatidylinositol-phospholipase C and phosphatidylinositol 3-kinase. (9279457)
1995
45
Human alpha beta T-cell receptor CD4-CD8 T-cell clones are predominantly Th0-like. (7790021)
1995
46
Constitutive expression of leukemia inhibitory factor RNA by human bone marrow stromal cells and modulation by IL-1, TNF-alpha, and TGF-beta. (1709108)
1991
47
Acute urethral obstruction due to condylomata acuminata. (1923242)
1991
48
Brachial artery rupture due to an exostosis: brief report. (3403628)
1988
49
Neonatal herpes simplex virus infection occurring in second twin of an asymptomatic mother. Failure of a modern protocol. (3025467)
1987
50

Variations for Acute Disseminated Encephalomyelitis

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Expression for genes affiliated with Acute Disseminated Encephalomyelitis

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Search GEO for disease gene expression data for Acute Disseminated Encephalomyelitis.

Pathways for genes affiliated with Acute Disseminated Encephalomyelitis

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Pathways related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

(show all 19)
idSuper pathwaysScoreTop Affiliating Genes
19.0HLA-DQA1, HLA-DQB1, HLA-DRB1
2
Show member pathways
9.0HLA-DQA1, HLA-DQB1, HLA-DRB1
3
Show member pathways
9.0HLA-DQA1, HLA-DQB1, HLA-DRB1
4
Show member pathways
9.0HLA-DQA1, HLA-DQB1, HLA-DRB1
5
Show member pathways
9.0HLA-DQA1, HLA-DQB1, HLA-DRB1
6
Show member pathways
9.0HLA-DQA1, HLA-DQB1, HLA-DRB1
79.0HLA-DQA1, HLA-DQB1, HLA-DRB1
8
Show member pathways
9.0HLA-DQA1, HLA-DQB1, HLA-DRB1
99.0HLA-DQA1, HLA-DQB1, HLA-DRB1
109.0HLA-DQA1, HLA-DQB1, HLA-DRB1
119.0HLA-DQA1, HLA-DQB1, HLA-DRB1
128.5HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
138.5HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
14
Show member pathways
8.5HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
15
Show member pathways
8.5HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
168.5HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
17
Show member pathways
8.5HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
18
Show member pathways
8.5HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1
197.7HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1, MPZ

GO Terms for genes affiliated with Acute Disseminated Encephalomyelitis

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Cellular components related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:00426139.9HLA-DQA1, HLA-DQB1
2integral component of lumenal side of endoplasmic reticulum membraneGO:00715569.7HLA-DQA1, HLA-DQB1
3endosome membraneGO:00100089.4HLA-DQA1, HLA-DQB1
4ER to Golgi transport vesicle membraneGO:00125079.0HLA-DQA1, HLA-DQB1, HLA-DRB1
5trans-Golgi network membraneGO:00325888.9HLA-DQA1, HLA-DQB1, HLA-DRB1

Biological processes related to Acute Disseminated Encephalomyelitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1immunoglobulin production involved in immunoglobulin mediated immune responseGO:00023819.7HLA-DQB1, HLA-DRB1
2antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIGO:00025049.5HLA-DQA1, HLA-DRB1
3antigen processing and presentationGO:00198828.5HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1

Sources for Acute Disseminated Encephalomyelitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet