ADE
MCID: ACT049
MIFTS: 56

Acute Disseminated Encephalomyelitis (ADE) malady

Neuronal category

Summaries for Acute Disseminated Encephalomyelitis

Sources:
43NIH Rare Diseases, 44NINDS, 64Wikipedia, 33MalaCards
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NIH Rare Diseases:43 Acute disseminated encephalomyelitis (adem) is a neurological condition characterized by a brief but intense attack of inflammation in the brain and spinal cord that damages myelin – the protective covering of nerve fibers.  it often follows viral infection, or less often, vaccination for measles, mumps, or rubella. treatment for adem is targeted at suppressing inflammation in the brain using anti-inflammatory drugs. plasmapheresis or intravenous immunoglobulin therapy may also be used.  additional treatment is symptomatic and supportive.  last updated: 10/31/2011

MalaCards: Acute Disseminated Encephalomyelitis, also known as acute disseminated encephalitis, is related to alzheimer's disease and neuromyelitis optica. An important gene associated with Acute Disseminated Encephalomyelitis is HCRT (hypocretin (orexin) neuropeptide precursor), and among its related pathways are Rheumatoid arthritis and Cytokines and Inflammatory Response. The compounds pge2 and octadecaneuropeptide have been mentioned in the context of this disorder. Affiliated tissues include liver, spinal cord and brain, and related mouse phenotypes are no phenotypic analysis and muscle.

NINDS:44 Acute disseminated encephalomyelitis (ADEM) is characterized by a brief but widespread attack of inflammation in the brain and spinal cord that damages myelin ? the protective covering of nerve fibers.

Wikipedia:64 Acute disseminated encephalomyelitis (ADEM) is an immune mediated disease of the brain. It usually... more...

Aliases & Classifications for Acute Disseminated Encephalomyelitis

Sources:
8Disease Ontology, 43NIH Rare Diseases, 44NINDS, 10DISEASES, 45Novoseek, 49Orphanet, 61UMLS, 35MeSH, 57SNOMED-CT, 40NCIt, 26ICD10 via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal


Characteristics (Orphanet epidemiological data):

49
acute disseminated encephalomyelitis:
Inheritance: Sporadic; Age of onset: Variable; Age of death: Normal


Aliases & Descriptions:

acute disseminated encephalomyelitis 8 43 44 10 49
acute disseminated encephalitis 8 49
adem 43 49
encephalomyelitis, acute disseminated 61
encephalomyelitis acute disseminated 45
ade 43


External Ids:

Disease Ontology8 DOID:639
MeSH35 D004673
NCIt40 C34578
SNOMED-CT57 83942000
ICD10 via Orphanet26 G04.0
ICD1025 G04.0

Related Diseases for Acute Disseminated Encephalomyelitis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Acute Disseminated Encephalomyelitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 475)
idRelated DiseaseScoreTop Affiliating Genes
1alzheimer's disease30.8HLA-DRB1, MPZ, HCRT, CNTF, AQP4
2neuromyelitis optica30.8MOG, MBP, AQP4
3measles30.7MBP
4transverse myelitis30.7MBP, AQP4
5subacute sclerosing panencephalitis30.7MOG, MBP
6hepatitis c30.6IL10, HLA-DRB1, TNF
7vaccinia30.4HLA-B
8plasmodium falciparum malaria30.4IL10, HLA-DRB1, HLA-B
9tetanus30.4MOG, MBP, HLA-B, MPZ, IL10
10systemic lupus erythematosus30.4TNF, HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1, IL10
11brain disease30.3MBP, HCRT, AQP4
12blindness30.2CNTF
13rheumatic fever30.2POMC
14narcolepsy30.2HCRT, HLA-DRB1
15relapsing-remitting multiple sclerosis30.2IL10, MBP, MOG
16adenocarcinoma30.2HLA-B, AQP4
17vasculitis30.2SAG, TNF, HLA-B
18tuberculosis30.2SAG, MBP, TNF, HLA-DQB1, HLA-DRB1, POMC
19asthma30.1MBP, TNF, HLA-B, HLA-DRB1, HLA-DQA1, POMC
20sleep disorder30.0HCRT
21arthritis30.0TNF, HLA-B, HLA-DRB1, POMC, IL10
22stroke, ischemic29.6AQP4
23allergic rhinitis29.6IL10
24acquired immunodeficiency syndrome29.6HLA-B
25polymyalgia rheumatica29.6HLA-DRB1
26polycystic ovary syndrome29.6POMC
27cystic fibrosis29.6HLA-DQA1
28atopy29.6HLA-DQA1, IL10
29cholera29.6CYTH1, POMC
30adenoma29.6POMC, HLA-B, SAG
31alcoholic hepatitis29.6IL10, TNF
32graft versus host disease29.6TNF, HLA-DRB1, IL10
33hyperlipidemia type 310.8
34hepatitis e10.6
35hepatitis d10.6
36hepatitis a10.6
37myelitis10.6
38acute transverse myelitis10.5
39japanese encephalitis10.4
40plasmodium vivax malaria10.4
41n syndrome10.4
42guillain-barr� syndrome10.4
43hypersomnia10.4
44acute hemorrhagic leukoencephalitis10.3
45alexia10.3
46aseptic meningitis10.3
47leptospirosis10.3
48gliomatosis cerebri10.3
49infectious mononucleosis10.3
50mutism10.3

Graphical network of the top 20 diseases related to Acute Disseminated Encephalomyelitis:



Diseases related to acute disseminated encephalomyelitis

Clinical Features for Acute Disseminated Encephalomyelitis

Drugs & Therapeutics for Acute Disseminated Encephalomyelitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Acute Disseminated Encephalomyelitis

Drug clinical trials:

Search ClinicalTrials for Acute Disseminated Encephalomyelitis

Search NIH Clinical Center for Acute Disseminated Encephalomyelitis

Search CenterWatch for Acute Disseminated Encephalomyelitis

Genetic Tests for Acute Disseminated Encephalomyelitis

Anatomical Context for Acute Disseminated Encephalomyelitis

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Acute Disseminated Encephalomyelitis:

33
Liver, Spinal cord, Brain, Lung, Bone marrow, Retina, Heart, Myeloid, T cells, B lymphoblasts, B cells

Animal Models for Acute Disseminated Encephalomyelitis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Acute Disseminated Encephalomyelitis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030129.6POMC, AQP4, CNTF
2MP:00053698.1HCRT, CNTF, IL10, TNF, PMP22, MOG
3MP:00053976.6POMC, HLA-B, IL10, CNTF, MPZ, MOG
4MP:00053846.6MOG, CNTF, POMC, MPZ, HLA-B, HLA-DQB1
5MP:00053876.4MBP, HLA-DQB1, MOG, HLA-DQA1, MPZ, HLA-B
6MP:00053866.4AQP4, HCRT, POMC, IL10, HLA-B, HLA-DQB1
7MP:00036315.7TNF, POMC, HCRT, AQP4, IL10, CYTH1

Publications for Acute Disseminated Encephalomyelitis

Sources:
51PubMed
See all sources

Articles related to Acute Disseminated Encephalomyelitis:

(show top 50)    (show all 500)
idTitleAuthorsYear
1
Isolated brain stem lesion in children: is it acute disseminated encephalomyelitis or not? (22766674)
2013
2
Acute disseminated encephalomyelitis. (23622336)
2013
3
Acute disseminated encephalomyelitis following biting by a scolopendra subspinipes mutilans. (23731374)
2013
4
Acute disseminated encephalomyelitis in two renal transplant patients: is there a role for Epstein-Barr virus reactivation? (23449733)
2013
5
Multiphasic acute disseminated encephalomyelitis (ADEM) following influenza type A (swine specific H1N1). (21997495)
2012
6
Severe acute disseminated encephalomyelitis: a paediatric intensive care population-based study. (20876155)
2011
7
Life-saving hemicraniectomy for fulminant acute disseminated encephalomyelitis. (21344963)
2011
8
Acute disseminated encephalomyelitis presenting as fever of unknown origin: case report. (22074226)
2011
9
An adverse event following 2009 H1N1 influenza vaccination: a case of acute disseminated encephalomyelitis. (22232625)
2011
10
Chronic sequelae of acute disseminated encephalomyelitis in a child. (20869688)
2010
11
Acute disseminated encephalomyelitis and multiple sclerosis. (20129937)
2010
12
Small cell lung carcinoma presenting with acute disseminated encephalomyelitis. (20197428)
2010
13
A (H1N1) influenza pneumonia with acute disseminated encephalomyelitis: a case report. (20934122)
2010
14
Acute disseminated encephalomyelitis: a 10-year cohort study in Thai children. (20350829)
2010
15
Acute disseminated encephalomyelitis following dengue hemorrhagic fever. (20739802)
2010
16
Differential diagnosis between acute disseminated encephalomyelitis and multiple sclerosis during the first episode. (18474751)
2008
17
Medical image. Thalamic lesion in a child. Acute disseminated encephalomyelitis (ADEM). (18256716)
2008
18
Neuroinvasion by Mycoplasma pneumoniae in acute disseminated encephalomyelitis. (18394283)
2008
19
Vasculitis and rheumatologic diseases may play role in the pathogenesis of acute disseminated encephalomyelitis (ADEM). (17258400)
2007
20
Alexia without agraphia in a child with acute disseminated encephalomyelitis. (16924040)
2006
21
Serum levels of matrix metalloproteinase-9 and its tissue inhibitor (TIMP-1) in acute disseminated encephalomyelitis. (16321449)
2006
22
Acute disseminated encephalomyelitis: an update. (16286539)
2005
23
Neuroimaging features of acute disseminated encephalomyelitis in childhood. (15607601)
2005
24
The transformation of pediatric gliomatosis cerebri to cerebellar glioblastoma multiforme presenting as supra- and infratentorial acute disseminated encephalomyelitis. Case report. (16206737)
2005
25
A common variable immunodeficient patient who developed acute disseminated encephalomyelitis followed by the Lennox-Gastaut syndrome. (15943601)
2005
26
Acute disseminated encephalomyelitis: clinical features and HLA-DR linkage. (15142232)
2004
27
Systemic lymphoma mimicking acute disseminated encephalomyelitis. (14984907)
2004
28
Acute disseminated encephalomyelitis in childhood: epidemiologic, clinical and laboratory features. (15295226)
2004
29
Heterogeneity in clinical presentation of acute disseminated encephalomyelitis (ADEM). (15626858)
2004
30
Acute disseminated encephalomyelitis: an MRI/MRS longitudinal study. (15165634)
2004
31
An unusual case of acute disseminated encephalomyelitis confined to brainstem. (15607107)
2004
32
Microangiopathy of brain, retina, and inner ear (Susac's syndrome) in an adolescent female presenting as acute disseminated encephalomyelitis. (15231946)
2004
33
Positive PCR for enterovirus in the cerebrospinal fluid of a child with acute disseminated encephalomyelitis. (15503109)
2004
34
Acute disseminated encephalomyelitis: recognition in the hands of general paediatricians. (12538312)
2003
35
Hemicraniectomy as a successful treatment of mass effect in acute disseminated encephalomyelitis. (12913218)
2003
36
Acute disseminated encephalomyelitis (ADEM) presenting with seizures secondary to anti-tetanus toxin vaccination. (15190671)
2003
37
Plasmapheresis in fulminant acute disseminated encephalomyelitis. (11578855)
2001
38
Myelin basic protein reactive Th2 T cells are found in acute disseminated encephalomyelitis. (9846815)
1998
39
Acute disseminated encephalomyelitis: an unusual cause of encephalitic syndrome in childhood. (9516630)
1998
40
Grand rounds--Hammersmith Hospitals. Distinguishing acute disseminated encephalomyelitis from multiple sclerosis. (8924845)
1996
41
Survey of herpes simplex virus infections of the central nervous system, including acute disseminated encephalomyelitis, in the Kyushu and Okinawa regions of Japan. (9345385)
1996
42
Cranial MRI findings in acute disseminated encephalomyelitis. (7744460)
1994
43
Acute disseminated encephalomyelitis probably related to a Mycoplasma pneumoniae infection. (8453818)
1993
44
Cranial computed tomography in acute disseminated encephalomyelitis. (2717010)
1989
45
Acute disseminated encephalomyelitis as a complication of treatment with gold. (3921144)
1985
46
Acute disseminated encephalomyelitis, with massive necrosis of the spinal cord, probably due to antitetanus serum. (14473939)
1962
47
The immunologic response to mice from stocks resistant and susceptible to acute disseminated encephalomyelitis. (13233630)
1955
48
Acute disseminated encephalomyelitis following immunization with homologous brain extracts; studies on the role of a circulating antibody in the production of the condition in dogs. (15428583)
1950
49
Experimental studies on acute disseminated encephalomyelitis in rhesus monkeys. (15413008)
1950
50
Acute disseminated encephalomyelitis produced in albino mice. (18149443)
1949

Genetic Variations for Acute Disseminated Encephalomyelitis

Expression for genes affiliated with Acute Disseminated Encephalomyelitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Acute Disseminated Encephalomyelitis

Search GEO for disease gene expression data for Acute Disseminated Encephalomyelitis.

Pathways for genes affiliated with Acute Disseminated Encephalomyelitis

Sources:
30KEGG, 38NCBI BioSystems Database, 12EMD Millipore, 54Reactome, 52QIAGEN, 56SinoBiological, 53R&D Systems
See all sources

Pathways related to Acute Disseminated Encephalomyelitis according to GeneCards/GeneDecks:

(show all 30)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9HLA-DPA1
29.2IL10, HLA-DRB1, TNF
39.2MPZ, MBP, PMP22
48.9AQP4, TNF, MBP
5
Immune response ICOS pathway in T-helper cell
Hide members
8.8HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
68.8HLA-DQA1, HLA-DRB1, HLA-DQB1, HLA-DPA1
78.8HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
8
Hide members
8.8HLA-DQA1, HLA-DRB1, HLA-DQB1, HLA-DPA1
98.8HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
10
Hide members
8.8HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
11
Hide members
8.8HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
128.8HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
13
Immune response NFAT in immune response
Hide members
8.8HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
14
Hide members
8.8HLA-DQA1, HLA-DRB1, HLA-DQB1, HLA-DPA1
15
Hide members
8.8HLA-DQA1, HLA-DRB1, HLA-DQB1, HLA-DPA1
16
Hide members
8.8HLA-DQA1, HLA-DRB1, HLA-DQB1, HLA-DPA1
17
Immune response Antigen presentation by MHC class II
Hide members
8.8HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
18
Hide members
8.8HLA-DQA1, HLA-DQB1, HLA-DPA1, TNF
198.7HLA-DQA1, HLA-B, HLA-DQB1, HLA-DPA1
208.4HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1, IL10
21
Hide members
8.4HLA-DQA1, HLA-DRB1, HLA-DQB1, HLA-DPA1, TNF
22
Hide members
8.3HLA-DPA1, HLA-DQB1, HLA-B, HLA-DRB1, HLA-DQA1
238.3HLA-DPA1, HLA-DQB1, HLA-B, HLA-DRB1, HLA-DQA1
24
Hide members
8.3HLA-DQA1, HLA-DRB1, HLA-B, HLA-DQB1, HLA-DPA1
258.1HLA-DPA1, HLA-DQB1, HLA-B, HLA-DRB1, HLA-DQA1, MPZ
26
Hide members
8.0TNF, HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1, IL10
278.0TNF, HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1, IL10
287.9HLA-DPA1, HLA-DQB1, HLA-B, HLA-DRB1, HLA-DQA1, IL10
29
Hide members
7.8TNF, HLA-DPA1, HLA-DQB1, HLA-B, HLA-DRB1, HLA-DQA1
30
Hide members
7.5IL10, TNF, HLA-DPA1, HLA-DQB1, HLA-B, HLA-DRB1

Compounds for genes affiliated with Acute Disseminated Encephalomyelitis

Sources:
45Novoseek, 50PharmGKB, 11DrugBank, 29IUPHAR, 60Tocris Bioscience, 24HMDB
See all sources

Compounds related to Acute Disseminated Encephalomyelitis according to GeneCards/GeneDecks:

(show top 50)    (show all 54)
idCompoundScoreTop Affiliating Genes
1pge24510.3POMC, SAG
2octadecaneuropeptide4510.2CNTF, HCRT
3clomipramine45 50 1112.1MPZ, IL10, HCRT
4amphetamine45 1111.0CNTF, POMC, HCRT
5dexamethasone45 50 29 1113.0POMC, AQP4, HCRT
6cdp5714510.0TNF, IL10
7opiate459.9POMC, SAG, HCRT
8interferon gamma459.9TNF, IL10
9cerebrosides459.8MBP, MPZ
10plp (139-151)609.7MBP, MOG
11mog (35-55)609.7MBP, MOG
12catecholamine459.7CNTF, HCRT, POMC
13nogo-66 (1-40)609.7MBP, MOG
14c3bot (154-182)609.7MOG, MBP
15ono 2506609.7MOG, MBP
162,3-cyclic nucleotide459.6MBP, MOG, MPZ
17dpa 1459.6HLA-DPA1, HLA-DRB1, HLA-DQA1
18lipoteichoic acid459.5IL10, HLA-B, TNF
19abacavir45 50 1111.5HLA-B, TNF
202,5-oligoadenylate459.5IL10, TNF, HLA-B
21polyinosinic-polycytidylic acid459.5TNF, HLA-B, IL10
22h2o2459.5MBP, CNTF
23carbamazepine45 50 1111.5POMC, HLA-B, TNF
24dodecylphosphocholine459.5POMC, MBP
25ganglioside459.4PMP22, MPZ, MBP, CNTF
26aspartate459.4PMP22, POMC, HLA-B, MPZ, SAG
27blys459.3TNF, IL10
28cyclosporin a45 29 6011.3SAG, MBP, HLA-B
29histamine45 29 2411.3AQP4, IL10, CNTF, HCRT, TNF
30cocaine45 1110.3CNTF, HCRT, MBP, POMC
31silver459.2HLA-DQA1, MOG, MBP
32corticosterone45 60 2411.1POMC, MBP, IL10, HCRT
33gaba459.1CNTF, PMP22, POMC, MBP, HCRT
34ivig459.0SAG, TNF, IL10, MBP
35acetylcholine45 50 29 11 2413.0MOG, MBP, CNTF, HCRT, POMC
36serine458.9MPZ, MOG, POMC, HLA-B, TNF, PMP22
37prednisolone45 29 1110.9POMC, MBP, TNF, IL10
38glatiramer acetate45 119.9MPZ, MBP, IL10, HLA-DRB1, MOG
39oligonucleotide458.8HLA-B, HLA-DQB1, HLA-DQA1, HLA-DRB1, AQP4, HCRT
40nitric oxide45 11 2410.8CNTF, HLA-B, IL10, HCRT, MOG, TNF
41norepinephrine45 11 2410.8POMC, HCRT, MBP, CNTF
42methotrexate45 50 1110.7TNF, IL10, MBP, HLA-DRB1
43glutamate458.6CNTF, MBP, CYTH1, SAG, AQP4, HCRT
44alanine458.6MBP, HLA-DRB1, HCRT, SAG, CNTF, POMC
45adenylate458.5POMC, SAG, MBP, CNTF, HCRT, HLA-B
46paraffin458.3HLA-DQA1, HLA-B, MBP, SAG, POMC, IL10
47retinoic acid45 249.1AQP4, CNTF, HLA-B, TNF, MBP, PMP22
48arginine457.8PMP22, CNTF, POMC, MPZ, HLA-DQA1, HLA-DRB1
49lipid457.5HCRT, CNTF, CYTH1, HLA-B, TNF, MBP
50tyrosine457.4HLA-DQB1, HLA-B, CYTH1, MBP, CNTF, SAG

GO Terms for genes affiliated with Acute Disseminated Encephalomyelitis

Sources:
16Gene Ontology
See all sources

Cellular components related to Acute Disseminated Encephalomyelitis according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1compact myelinGO:0432189.3PMP22, MBP
2MHC class II protein complexGO:0426139.0HLA-DQA1, HLA-DPA1, HLA-DRB1, HLA-DQB1
3clathrin-coated endocytic vesicle membraneGO:0306699.0HLA-DQA1, HLA-DRB1, HLA-DQB1, HLA-DPA1
4transport vesicle membraneGO:0306589.0HLA-DQA1, HLA-DPA1, HLA-DQB1, HLA-DRB1
5trans-Golgi network membraneGO:0325889.0HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
6endocytic vesicle membraneGO:0306668.9HLA-DPA1, HLA-DQA1, HLA-DRB1, HLA-DQB1
7lysosomal membraneGO:0057658.8HLA-DQA1, HLA-DPA1, HLA-DQB1, HLA-DRB1
8integral to lumenal side of endoplasmic reticulum membraneGO:0715568.6HLA-DQB1, HLA-B, HLA-DRB1, HLA-DQA1, HLA-DPA1
9ER to Golgi transport vesicle membraneGO:0125078.5HLA-DRB1, HLA-DQB1, HLA-DPA1, HLA-B, HLA-DQA1
10Golgi membraneGO:0001398.0HLA-DQA1, HLA-DPA1, HLA-DQB1, HLA-B, HLA-DRB1
11integral to plasma membraneGO:0058877.7TNF, HLA-DPA1, HLA-B, HLA-DRB1, MPZ, AQP4
12plasma membraneGO:0058865.6HLA-B, AQP4, CYTH1, MPZ, HLA-DQA1, HLA-DRB1

Biological processes related to Acute Disseminated Encephalomyelitis according to GeneCards/GeneDecks:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of cytokine secretion involved in immune responseGO:00274010.3IL10
2immunoglobulin production involved in immunoglobulin mediated immune responseGO:0023819.9HLA-DRB1, HLA-DQB1
3cellular response to estradiol stimulusGO:0713929.8AQP4, IL10
4receptor biosynthetic processGO:0328009.8TNF, IL10
5humoral immune response mediated by circulating immunoglobulinGO:0024559.8HLA-DRB1, HLA-DQB1
6detection of bacteriumGO:0160459.4HLA-DRB1, HLA-B
7response to glucocorticoid stimulusGO:0513849.4TNF, IL10, AQP4
8negative regulation of growth of symbiont in hostGO:0441309.3IL10, TNF
9T cell costimulationGO:0312959.1HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
10T cell receptor signaling pathwayGO:0508529.0HLA-DPA1, HLA-DQB1, HLA-DRB1, HLA-DQA1
11antigen processing and presentation of exogenous peptide antigen via MHC class IIGO:0198869.0HLA-DQA1, HLA-DRB1, HLA-DQB1, HLA-DPA1
12interferon-gamma-mediated signaling pathwayGO:0603338.6HLA-DQA1, HLA-DRB1, HLA-B, HLA-DQB1, HLA-DPA1
13cytokine-mediated signaling pathwayGO:0192218.5HLA-DQA1, HLA-DRB1, HLA-B, HLA-DQB1, HLA-DPA1
14immune responseGO:0069557.7MBP, HLA-DPA1, HLA-DQB1, HLA-B, HLA-DRB1, HLA-DQA1

Molecular functions related to Acute Disseminated Encephalomyelitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class II receptor activityGO:0323958.8HLA-DQA1, HLA-DRB1, HLA-DQB1, HLA-DPA1

Products for genes affiliated with Acute Disseminated Encephalomyelitis

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Sources for Acute Disseminated Encephalomyelitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet