MCID: ACT012
MIFTS: 39

Acute Hemorrhagic Conjunctivitis malady

Summaries for Acute Hemorrhagic Conjunctivitis

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8Disease Ontology, 32MalaCards
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Disease Ontology:8 A viral infectious disease that results in inflammation located in conjunctiva, has material basis in human coxsackievirus a24 or has material basis in human enterovirus 70, which are transmitted by contaminated fomites or transmitted by contact with contaminated hands. the infection has symptom vascular dilation, has symptom eyelid edema, has symptom photophobia, has symptom redness of the eyes, has symptom watering of the eye, has symptom conjunctival congestion, and has symptom superficial punctate epithelial keratitis.

MalaCards: Acute Hemorrhagic Conjunctivitis, also known as epidemic hemorrhagic conjunctivitis, is related to acute conjunctivitis and conjunctivitis, and has symptoms including superficial punctate epithelial keratitis, conjunctival congestion and watering of the eye. An important gene associated with Acute Hemorrhagic Conjunctivitis is NR0B1 (nuclear receptor subfamily 0, group B, member 1), and among its related pathways are Hematopoietic cell lineage and Cytokine Network. The drugs emedastine and emedastine difumarate and the compounds n-formylmethionyl-leucylphenylalanine and progesterone have been mentioned in the context of this disorder. Affiliated tissues include eye, kidney and colon.

Aliases & Classifications for Acute Hemorrhagic Conjunctivitis

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 27ICD9CM, 39NCIt, 34MeSH
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Aliases & Descriptions:

acute hemorrhagic conjunctivitis 8 10
epidemic hemorrhagic conjunctivitis 8
conjunctivitis, acute hemorrhagic 60
apollo disease 8


External Ids:

Disease Ontology8 DOID:11227
ICD9CM27 077.4
NCIt39 C34505
MeSH34 D003232

Related Diseases for Acute Hemorrhagic Conjunctivitis

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17GeneCards, 18GeneDecks
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Diseases related to Acute Hemorrhagic Conjunctivitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1acute conjunctivitis11.1
2conjunctivitis11.1
3hemorrhagic disease10.3
4adult syndrome10.1
5dermatitis10.1
6eye disease10.1
7keratoconjunctivitis10.1
8measles10.0CD55
9meningitis10.0CD55
10pyelonephritis10.0CD55, DPEP1
11ulcerative colitis10.0DPEP1, CD55, IL1A
12osteosarcoma10.0IL1A, CD55, DPEP1
13hypersensitivity reaction type ii disease10.0NR0B1, CD55, IL1A
14ovarian cancer10.0IL1A, CD55, NR0B1

Graphical network of diseases related to Acute Hemorrhagic Conjunctivitis:



Diseases related to acute hemorrhagic conjunctivitis

Clinical Features for Acute Hemorrhagic Conjunctivitis

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8Disease Ontology
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Symptoms:

8 (show all 7)
  • superficial punctate epithelial keratitis
  • conjunctival congestion
  • watering of the eye
  • eyelid edema
  • vascular dilation
  • redness of the eyes
  • photophobia

Drugs & Therapeutics for Acute Hemorrhagic Conjunctivitis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Acute Hemorrhagic Conjunctivitis

Drug clinical trials:

Search ClinicalTrials for Acute Hemorrhagic Conjunctivitis

Search NIH Clinical Center for Acute Hemorrhagic Conjunctivitis

Search CenterWatch for Acute Hemorrhagic Conjunctivitis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Acute Hemorrhagic Conjunctivitis

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Anatomical Context for Acute Hemorrhagic Conjunctivitis

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32MalaCards
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MalaCards organs/tissues related to Acute Hemorrhagic Conjunctivitis:

32
Eye, Kidney, Colon, Endothelial

Animal Models for Acute Hemorrhagic Conjunctivitis or affiliated genes

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Publications for Acute Hemorrhagic Conjunctivitis

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50PubMed
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Articles related to Acute Hemorrhagic Conjunctivitis:

(show top 50)    (show all 111)
idTitleAuthorsYear
1
Molecular characterization and phylogenetic study of coxsackievirus A24v causing outbreaks of acute hemorrhagic conjunctivitis (AHC) in Brazil. (21858030)
2011
2
An outbreak of acute hemorrhagic conjunctivitis (AHC) caused by coxsackievirus A24 variant in Pakistan. (18638510)
2008
3
Outbreak of acute hemorrhagic conjunctivitis in Maharashtra and Gujarat states of India, caused by Coxsackie virus A-24 variant. (17457917)
2007
4
Two outbreaks of acute hemorrhagic conjunctivitis in Africa due to genotype III coxsackievirus A24 variant. (17294159)
2007
5
Acute hemorrhagic conjunctivitis epidemic caused by coxsackievirus A24 variants in Korea during 2002-2003. (16299722)
2006
6
Rapid identification of the coxsackievirus A24 variant by molecular serotyping in an outbreak of acute hemorrhagic conjunctivitis. (15750062)
2005
7
Towards an in vitro model for acute hemorrhagic conjunctivitis: cytokine-mediated vascular endothelial cell activation triggered by enterovirus type 70 infection. (15072749)
2004
8
Acute hemorrhagic conjunctivitis outbreak caused by Coxsackievirus A24--Puerto Rico, 2003. (15269699)
2004
9
Acute hemorrhagic conjunctivitis caused by coxsackievirus A24 variant, South Korea, 2002. (12967504)
2003
10
Acute hemorrhagic conjunctivitis epidemic--2003 in Nepal. (15024766)
2003
11
Acute hemorrhagic conjunctivitis--St. Croix, U.S. Virgin Islands, September-October 1998. (9810014)
1998
12
Corneal superinfection in acute hemorrhagic conjunctivitis. (9820942)
1998
13
From the Centers for Disease Control and Prevention. Acute hemorrhagic conjunctivitis--St Croix, US Virgin Islands, September-October 1998. (9842938)
1998
14
Acute hemorrhagic conjunctivitis outbreak in Thailand, 1992. (9279984)
1996
15
Analysis of neutralizing antibodies to Enterovirus 70 and Coxsackievirus A24 variant, levels of immunoglobulins and total protein in tears of patients with acute hemorrhagic conjunctivitis. (22823272)
1995
16
Inhibition of the enteroviruses that cause acute hemorrhagic conjunctivitis (AHC) by benzimidazoles; enviroxime (LY 122772) and enviradone (LY 127123). (8540755)
1995
17
Acute hemorrhagic conjunctivitis due to enterovirus 70 in American Samoa: serum-neutralizing antibodies and sex-specific protection. (1337662)
1992
18
Acute hemorrhagic conjunctivitis. (1309404)
1992
19
Evolutionary study on the Coxsackievirus A 24 variant causing acute hemorrhagic conjunctivitis by oligonucleotide mapping analysis of RNA genome. (2171464)
1990
20
Leads from the MMWR. Acute hemorrhagic conjunctivitis caused by coxsackievirus A24--Caribbean. (3586222)
1987
21
Acute hemorrhagic conjunctivitis caused by coxsackievirus A24--Caribbean. (3104763)
1987
22
Acute hemorrhagic conjunctivitis epidemic in Colon, Republic of Panama. (3946379)
1986
23
Acute hemorrhagic conjunctivitis caused by enterovirus type 70: an epidemic in American Samoa. (2994502)
1985
24
Acute hemorrhagic conjunctivitis in Central America: first enterovirus epidemic in the western hemisphere. (3994224)
1985
25
Rapid immunofluorescence diagnosis of acute hemorrhagic conjunctivitis caused by enterovirus 70. (6307917)
1983
26
Dysautonomia in acute hemorrhagic conjunctivitis. (6674310)
1983
27
Polio-like motor paralysis associated with acute hemorrhagic conjunctivitis in an outbreak in 1981 in Bombay, India: clinical and serologic studies. (6842006)
1983
28
Oligonucleotide fingerprint analysis of enterovirus 70 isolates from the 1980 to 1981 pandemic of acute hemorrhagic conjunctivitis: evidence for a close genetic relationship among Asian and American strains. (6307877)
1983
29
Acute hemorrhagic conjunctivitis--American Samoa. (6799764)
1982
30
Acute hemorrhagic conjunctivitis--Panama and Belize, 1981. (6793825)
1981
31
Isolation of enterovirus 70 from patients with acute hemorrhagic conjunctivitis in Key West, Florida. (6273726)
1981
32
Acute hemorrhagic conjunctivitis--Florida, North Carolina. (6793826)
1981
33
Acute hemorrhagic conjunctivitis--Key West, Florida. (6792491)
1981
34
Acute hemorrhagic conjunctivitis--Florida. (6792492)
1981
35
Acute hemorrhagic conjunctivitis--Latin America. (6792487)
1981
36
Seroepidemiologic studies of acute hemorrhagic conjunctivitis virus (enterovirus type 70) in West Africa. I. Studies with human sera from Ghana collected eight years after the first outbreak. (7304562)
1981
37
Replication of acute hemorrhagic conjunctivitis viruses in conjunctival-corneal cell cultures of mice, rabbits, and monkeys. (6254904)
1980
38
Antigenic analysis of acute hemorrhagic conjunctivitis viruses (enterovirus type 70). (94146)
1979
39
Serological studies of radiculomyelitis occurring during the outbreak of acute hemorrhagic conjunctivitis in Senegal in 1970. (184327)
1976
40
Acute hemorrhagic conjunctivitis in Tunisia. Report of viral isolations. (1247410)
1976
41
An epidemic of acute hemorrhagic conjunctivitis in Sendai area, 1973-1974. (189457)
1976
42
Growth characteristics of acute hemorrhagic conjunctivitis (AHC) virus in monkey kidney cells. II. Temperature sensitivity of the isolates obtained at various epidemic areas. (188780)
1976
43
Letter: Acute hemorrhagic conjunctivitis associated with adenovirus Type 19. (163967)
1975
44
Neurologic complications with elevated antibody titer after acute hemorrhagic conjunctivitis. (171960)
1975
45
Serologic characterization and sero-epidemiologic studies on acute hemorrhagic conjunctivitis (AHC) virus. (165719)
1975
46
An outbreak of acute hemorrhagic conjunctivitis in Thailand. 2. Epidemiologic investigation. (4832763)
1974
47
Acute hemorrhagic conjunctivitis. (4612807)
1974
48
A new form of acute conjunctivitis epidemic in Taiwan. A simultaneous outbreak of adenovirus type II and "acute hemorrhagic conjunctivitis" virus infections. (4369724)
1974
49
Neurologic complications associated with acute hemorrhagic conjunctivitis virus infection and its serologic confirmation. (4363000)
1974
50
The stability of acute hemorrhagic conjunctivitis virus. (4479311)
1974

Genetic Variations for Acute Hemorrhagic Conjunctivitis

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Expression for genes affiliated with Acute Hemorrhagic Conjunctivitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Acute Hemorrhagic Conjunctivitis

Search GEO for disease gene expression data for Acute Hemorrhagic Conjunctivitis.

Pathways for genes affiliated with Acute Hemorrhagic Conjunctivitis

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29KEGG, 51QIAGEN
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Pathways related to Acute Hemorrhagic Conjunctivitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5IL1A, CD55
29.4IL1A, IFNA7
3
Hide members
8.9IL1A, CD55, IFNA7

Compounds for genes affiliated with Acute Hemorrhagic Conjunctivitis

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44Novoseek, 59Tocris Bioscience, 28IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Acute Hemorrhagic Conjunctivitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1n-formylmethionyl-leucylphenylalanine449.4IL1A, CD55
2progesterone44 59 28 11 2413.2IL1A, CD55, NR0B1
3creatinine448.4IL1A, CD55, DPEP1

GO Terms for genes affiliated with Acute Hemorrhagic Conjunctivitis

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16Gene Ontology
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Cellular components related to Acute Hemorrhagic Conjunctivitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1anchored to membraneGO:0312259.1CD55, DPEP1
2apical plasma membraneGO:0163248.3CD55, DPEP1, MTDH

Biological processes related to Acute Hemorrhagic Conjunctivitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of angiogenesisGO:0457669.5IL1A, MTDH

Products for genes affiliated with Acute Hemorrhagic Conjunctivitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Acute Hemorrhagic Conjunctivitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet