MCID: ACT071
MIFTS: 48

Acute Kidney Failure

Categories: Nephrological diseases, Genetic diseases

Aliases & Classifications for Acute Kidney Failure

MalaCards integrated aliases for Acute Kidney Failure:

Name: Acute Kidney Failure 38 12 14
Kidney Failure, Acute 69
Renal Failure Acute 52

Classifications:



External Ids:

Disease Ontology 12 DOID:3021
ICD10 33 N17 N17.1 N17.2

Summaries for Acute Kidney Failure

MalaCards based summary : Acute Kidney Failure, also known as kidney failure, acute, is related to kidney cortex necrosis and korean hemorrhagic fever. An important gene associated with Acute Kidney Failure is PIK3C2A (Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha), and among its related pathways/superpathways is Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Dopamine and Fenoldopam have been mentioned in the context of this disorder. Affiliated tissues include Bone and Adipose, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Acute Kidney Failure

Diseases in the Kidney Disease family:

Acute Kidney Failure Chronic Kidney Failure
Renal Infectious Disease Ren-Related Kidney Disease

Diseases related to Acute Kidney Failure via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 91)
id Related Disease Score Top Affiliating Genes
1 kidney cortex necrosis 10.9
2 korean hemorrhagic fever 10.8
3 hemolytic-uremic syndrome 10.8
4 phosphoribosylpyrophosphate synthetase superactivity 10.8
5 cranial nerve disease 10.7 EGF PIK3C2A
6 mesomelia 10.7 B2M IL18
7 visual snow syndrome 10.7 MB PIK3C2A
8 endometrial type cervical adenomyoma 10.6 MB PIK3C2A
9 cataract 25 10.6 ALB B2M
10 myopathy, distal, tateyama type 10.6 MB PIK3C2A
11 velocardiofacial syndrome 10.6 MB PIK3C2A
12 properdin deficiency 10.6 MB NPPA
13 inferior myocardial infarction 10.6 MB PIK3C2A
14 astrocytoma 10.6 ALB B2M
15 immune-complex glomerulonephritis 10.6 ALB B2M
16 hereditary choroidal atrophy 10.5 MB PIK3C2A
17 cataract 10.5 ALB HGF
18 adrenal gland disease 10.5 ALB B2M
19 localized chondrosarcoma 10.5 ALB PIK3C2A
20 glomerulonephritis 10.5 MB PIK3C2A
21 atrial septal defect 7, with or without av conduction defects 10.5 NPPA REN
22 hypodontia of incisors and premolars 10.5 NPPA REN
23 repetitive stress injuries 10.5 NPPA REN
24 synovial chondromatosis 10.5 ALB NPPA
25 esophageal atresia 10.5 EGF PIK3C2A
26 clitoris cancer 10.5 NPPA REN
27 pyrimidine metabolic disorder 10.4 ALB PIK3C2A
28 thrombotic thrombocytopenic purpura 10.4 B2M REN
29 acrofacial dysostosis 10.4 ALB EGF
30 yellow fever 10.4 ALB IL18
31 acute kidney tubular necrosis 10.4
32 common cold 10.4 ALB PIK3C2A
33 adult respiratory distress syndrome 10.4 MB NPPA PIK3C2A
34 wernicke-korsakoff syndrome 10.4 ALB REN
35 pulpitis 10.4 ALB B2M EGF
36 iga glomerulonephritis 10.3 ALB REN
37 glycogen storage disease viii 10.3 B2M REN
38 eustachian tube disease 10.3 B2M REN
39 brachial plexus neuropathy 10.3 MB PIK3C2A
40 acanthoma 10.3 CFH EGF
41 rete ovarii adenoma 10.3 ALB MB PIK3C2A
42 specific bursitis often of occupational origin 10.3 B2M CST3
43 urinary bladder posterior wall cancer 10.3 NPPA PIK3C2A REN
44 uterine corpus sarcoma 10.2 HGF IL18
45 plantar fasciitis 10.2 MB PIK3C2A
46 craniosynostosis 10.2 NPPA PIK3C2A REN
47 microphthalmia, isolated, with coloboma 7 10.2 MB PIK3C2A REN
48 non-congenital cyst of kidney 10.2 ALB B2M REN
49 childhood brainstem astrocytoma 10.2 HGF TYR
50 porphyria, acute hepatic 10.1 ADAMTS13 CFH

Comorbidity relations with Acute Kidney Failure via Phenotypic Disease Network (PDN): (show top 50) (show all 99)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Cystitis Acute Myocardial Infarction
Acute Pancreatitis Acute Proliferative Glomerulonephritis
Alcoholic Liver Cirrhosis Alzheimer Disease
Aortic Aneurysm Aplastic Anemia
Bacteremia Benign Renovascular Hypertension
Bladder Neck Obstruction Bleeding Disorder, Platelet-Type, 11
Bronchitis Bronchopneumonia
Candidiasis Cardiac Arrest
Cardiogenic Shock Chronic Kidney Failure
Chronic Myocardial Ischemia Chronic Rapidly Progressive Glomerulonephritis
Colorectal Cancer Cystitis
Decubitus Ulcer Deficiency Anemia
Dermatomycosis Diabetic Polyneuropathy
Disseminated Intravascular Coagulation Encephalopathy
Esophageal Candidiasis Familial Atrial Fibrillation
First-Degree Atrioventricular Block Generalized Atherosclerosis
Goodpasture Syndrome Gout
Heart Disease Hemolytic-Uremic Syndrome
Hepatic Encephalopathy Hepatitis
Hepatorenal Syndrome Hydronephrosis
Hypertension, Essential Hypertensive Encephalopathy
Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis Hypoglycemia
Hypoglycemic Coma Hypothyroidism
Intermediate Coronary Syndrome Intestinal Obstruction

Graphical network of the top 20 diseases related to Acute Kidney Failure:



Diseases related to Acute Kidney Failure

Symptoms & Phenotypes for Acute Kidney Failure

MGI Mouse Phenotypes related to Acute Kidney Failure:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.14 TYR B2M CFH CST3 HGF IL18
2 homeostasis/metabolism MP:0005376 10.03 ADAMTS13 ALB B2M CFH CST3 IL18
3 growth/size/body region MP:0005378 10.02 B2M EGF HGF IL18 MB PIK3C2A
4 hematopoietic system MP:0005397 10.02 HGF IL18 MB NPPA PIK3C2A REN
5 mortality/aging MP:0010768 9.93 ADAMTS13 ALB B2M CFH CST3 HGF
6 muscle MP:0005369 9.43 ALB CST3 IL18 MB NPPA REN
7 renal/urinary system MP:0005367 9.17 ALB CFH NPPA PIK3C2A REN SLC22A12

Drugs & Therapeutics for Acute Kidney Failure

Drugs for Acute Kidney Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 664)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
2
Fenoldopam Approved Phase 4,Phase 3,Phase 2 67227-56-9, 67227-57-0 3341
3
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3 76631-46-4, 113775-47-6 68602 5311068 56032
4
Heparin Approved, Investigational Phase 4,Phase 3 9005-49-6 772 46507594
5
Bisacodyl Approved Phase 4 603-50-9
6
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 159351-69-6 6442177
7
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 22916-47-8 4189
8
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 128794-94-5 5281078
9
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 24280-93-1 446541
10
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
11
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 53123-88-9 5284616 6436030 46835353
12
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 104987-11-3 445643 439492
13
Alprostadil Approved, Investigational Phase 4 745-65-3 149351
14
Spironolactone Approved Phase 4,Phase 2,Phase 3 1952-01-7, 52-01-7 5833
15
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1 103-90-2 1983
16
Clonidine Approved Phase 4 4205-90-7 2803
17
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
18
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
19
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
20
Ticagrelor Approved Phase 4,Phase 3 274693-27-5 9871419
21
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
22
Acetylcysteine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 616-91-1 12035
23
Benzocaine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 1994-09-7, 94-09-7 2337
24
Nafamostat Approved, Investigational Phase 4,Phase 3 81525-10-2
25
Dalteparin Approved Phase 4,Phase 3 9005-49-6
26
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
27
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2 28523-86-6 5206
28
Daptomycin Approved, Investigational Phase 4,Phase 3 103060-53-3 16129629
29
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
30
Desflurane Approved Phase 4 57041-67-5 42113
31
Remifentanil Approved Phase 4 132875-61-7 60815
32
Zinc Approved Phase 4,Phase 3,Phase 2 7440-66-6 32051 23994
33
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 54-31-9 3440
34
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
35
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
36
Basiliximab Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 152923-56-3, 179045-86-4
37
Nitroglycerin Approved, Investigational Phase 4,Phase 3,Phase 2 55-63-0 4510
38
Cisplatin Approved Phase 4,Phase 2,Phase 3,Phase 1 15663-27-1 84093 441203 2767
39
Milrinone Approved Phase 4,Phase 2 78415-72-2 4197
40
Iron Approved Phase 4,Phase 3,Phase 2 7439-89-6 23925
41
Aspirin Approved, Vet_approved Phase 4,Phase 3 50-78-2 2244
42
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-02-2 5743
43
Piperacillin Approved Phase 4,Phase 1 66258-76-2 43672
44
Tazobactam Approved Phase 4,Phase 1 89786-04-9 123630
45
Vancomycin Approved Phase 4,Phase 3,Phase 1 1404-90-6 441141 14969
46
Metolazone Approved Phase 4 17560-51-9 4170
47
Epoprostenol Approved Phase 4 61849-14-7, 35121-78-9 5280427 5282411
48
Aminophylline Approved Phase 4,Early Phase 1 317-34-0 9433
49
Terlipressin Approved, Investigational Phase 4,Phase 2 14636-12-5 72081
50
Ertapenem Approved, Investigational Phase 4 153832-46-3 150610

Interventional clinical trials:

(show top 50) (show all 1182)

id Name Status NCT ID Phase Drugs
1 Fenoldopam for Prevention of Acute Kidney Injury Unknown status NCT01690832 Phase 4 standard saline infusion;fenoldopam infusion
2 Pirfenidone Effect on the Recovery of Renal Function in Septic Acute Kidney Injury Unknown status NCT02530359 Phase 4 Pirfenidone extended release;Placebo equivalent
3 Short-Term Alpha Lipoic Acid Therapy for Prevention of Contrast-induced Acute Kidney Injury and Endothelial Dysfunction in Type 2 Diabetes Unknown status NCT01978405 Phase 4 Alpha lipoic acid
4 Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury Unknown status NCT00837057 Phase 4
5 The Effects of Dexmedetomidine on Postoperative Renal Function in Valvular Heart Surgery Unknown status NCT01886079 Phase 4 dexmedetomidine;Saline
6 Limiting IV Chloride to Reduce AKI After Cardiac Surgery Unknown status NCT02020538 Phase 4
7 Citrate Versus Heparin for the Lock of Non-tunneled Hemodialysis Catheters in Patients Hospitalised in ICU Unknown status NCT01962116 Phase 4 Citrate 4%;unfractionated heparin
8 Comparison of Slow Efficiency Daily Dialysis (SLEDD) With Unfractionated Heparin Versus Citrasate in Critically Ill Patients. Unknown status NCT01228292 Phase 4 Unfractionated heparin;Citrasate
9 Efficacy and Safety of Heparin-coated Surface-treated Polyacrylonitrile Membrane Hemofilter in Critical Ill CRRT Patients Unknown status NCT02355873 Phase 4
10 Protective Effects of Oral L-Arginine CI-AKI Unknown status NCT02455960 Phase 4
11 Safety and Efficacy of OsmoPrep® Tablets Versus HalfLytely® and Bisacodyl Tablet Bowel Prep Kit for Colon Cleansing Unknown status NCT01427296 Phase 4 Polyethylene glycol;Oral sodium phosphate solution
12 Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant Unknown status NCT01239472 Phase 4 everolimus
13 Efficacy and Safety of Alprostadil Prevent Contrast Induced Nephropathy Unknown status NCT01722513 Phase 4 Alprostadil ﹠control
14 Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure Unknown status NCT00527059 Phase 4 Levosimendan in addition to standard therapy;spironolactone, beta-blockers,ecc
15 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
16 Platelet Resistance With Ticagrelor or Standard-Dose Clopidogrel Among CKD and ACS Patients Unknown status NCT02459288 Phase 4 Clopidogrel first;Ticagrelor first
17 Augmented Vs. Normal Renal Replacement Therapy in Severe Acute Renal Failure (ARF). Completed NCT00221013 Phase 4
18 Metabolic Pattern of Cyclosporine A and Acute Renal Failure Completed NCT00264355 Phase 4 cyclosporine A
19 Effect of the Intensity of Continuous Renal Replacement Therapy in Patients With Acute Kidney Injury Completed NCT01560650 Phase 4
20 Effect of N-acetylcysteine on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass Graft Completed NCT01394419 Phase 4 N-acetylcysteine;Saline
21 The Optimal Mode of Renal Replacement Therapy in Acute Kidney Injury (OMAKI) Study Completed NCT00675818 Phase 4
22 Hannover Dialysis Outcome Study Completed NCT00529139 Phase 4
23 The Effect of Atorvastatin on Prevention of Postoperative Acute Kidney Injury in Patients Undergoing Aortic Surgery Completed NCT02157337 Phase 4 Atorvastatin;placebo
24 Prostacyclin's Effect on Platelet Responsiveness Completed NCT00890214 Phase 4 prostacyclin;heparin
25 Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2) Completed NCT01870804 Phase 4 Rosuvastatin;Atorvastatin
26 Rosuvastatin Prevent Contrast Induced Acute Kidney Injury in Patients With Diabetes Completed NCT00786136 Phase 4 rosuvastatin
27 Aminophylline and Contrast Induced Nephropathy in Acute Myocardial Infarction Completed NCT01594489 Phase 4 Aminophylline;Hydration plus N-acetylcisteine
28 Prevention of Acute Kidney Injury by Erythropoietin in Thoracic Aorta Surgery With Hypothermic Cardiac Arrest Completed NCT01369732 Phase 4 recombinant human erythropoietin;saline
29 Personalized Versus Standard Hydration for Prevention of CI-AKI: a Randomized Trial With Bioimpedance Analysis Completed NCT02225431 Phase 4 sodium chloride infusion
30 Citrate-based Regional Anticoagulation Versus Heparin for Continuous Renal Replacement Therapy Completed NCT01269112 Phase 4
31 Early Hydration in Acute Myocardial Infarction Completed NCT01742130 Phase 4 sodium bicarbonate solution;Isotonic saline
32 Efficacy of RIPC to Reduce AKI for Patients Undergoing PCI Completed NCT02195726 Phase 4
33 Perioperative Evaluation of Terlipressin Infusion During Living Donor Liver Transplantation on Incidence of Acute Kidney Completed NCT02059460 Phase 4 Terlipressin;placebo
34 Pharmacokinetics of Ertapenem in Continuous Venovenous Hemodialysis Completed NCT00877370 Phase 4 ertapenem
35 Trial to Assess the Efficacy and Safety of Nafamostat Mesilate During Continuous Renal Replacement Therapy Completed NCT02478242 Phase 4 Nafamostat mesilate;Normal saline
36 Nadroparin Anticoagulation for Continuous Venovenous Hemofiltration Completed NCT00965328 Phase 4
37 A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized Trial Completed NCT02009280 Phase 4 Administration of anesthesia: Propofol;Administration of anesthesia: Sevoflurane
38 The Effect of Nafamostat Mesilate in Prolonging Filter Patency With Patients on Continuous Renal Replacement Therapy Completed NCT01761994 Phase 4 Anticoagulation with nafamostat mesilate
39 Biological and Clinical Measurements Following Systemic Leakage When a Citrate or Heparin Lock is Used Completed NCT02860299 Phase 4 citrate 4%;unfractionated heparin
40 IVUS Guidance to Reduce Contrast in Coronary Angioplasty Completed NCT01947335 Phase 4
41 PROMISS: Simvastatin Prevents the Contrast Induced Acute Renal Failure in Patients With Renal Insufficiency Undergoing Coronary Angiography Completed NCT00259441 Phase 4 Simvastatin
42 Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration Completed NCT01866397 Phase 4
43 INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery Completed NCT01020409 Phase 4
44 Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery Completed NCT01669434 Phase 4 Take ACE-I;Hold ACE-I
45 Fenoldopam and Splanchnic Perfusion During Cardiopulmonary Bypass Completed NCT00747331 Phase 4 Fenoldopam mesilate;Placebo
46 Pharmacokinetics of Daptomycin in Critically Ill Patients Receiving Continuous Venovenous Hemodialysis (CVVHD) Completed NCT00663403 Phase 4 Daptomycin
47 Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach Completed NCT02135146 Phase 4 Plasmalyte 3ml/kg/hr group;Plasmalyte 6ml/kg/hr group
48 Everolimus in de Novo Heart Transplant Recipients Completed NCT01017029 Phase 4 Everolimus;Mycophenolate mofetil + Everolimus
49 Renal Safety Evaluation After Dotarem®-Enhanced MRI Completed NCT00650845 Phase 4 Dotarem®-enhanced MRI
50 A Randomized Trial of Rosuvastatin in Elective Angioplasty to Prevent Contrast-induced Nephropathy (CLEAR-CIN). Completed NCT02737319 Phase 4 Rosuvastatin

Search NIH Clinical Center for Acute Kidney Failure

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Acute Kidney Failure cell therapies at LifeMap Discovery.

Genetic Tests for Acute Kidney Failure

Anatomical Context for Acute Kidney Failure

MalaCards organs/tissues related to Acute Kidney Failure:

39
Kidney, Heart, Liver, Neutrophil, Testes, Lung, Endothelial
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Acute Kidney Failure:
id Tissue Anatomical CompartmentCell Relevance
1 Bone Bone Marrow Bone Marrow Stromal Cells Potential therapeutic candidate
2 Adipose Subcutaneous White Adipose Mesenchymal Stem Cells Potential therapeutic candidate
3 Kidney Proximal Tubule Proximal Tubule Cells Potential therapeutic candidate, affected by disease

Publications for Acute Kidney Failure

Articles related to Acute Kidney Failure:

(show all 50)
id Title Authors Year
1
Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure. ( 28551825 )
2017
2
Acute kidney failure due to polyarteritis nodosa. ( 27939915 )
2017
3
Pemetrexed-induced acute kidney failure following irreversible renal damage: two case reports and literature review. ( 28491851 )
2017
4
Proliferative C4 Dense Deposit Disease, Acute ThromboticA Microangiopathy, a Monoclonal Gammopathy, andA Acute Kidney Failure. ( 26704376 )
2016
5
Inhibition of Notch Signaling Ameliorates Acute Kidney Failure and Downregulates Platelet-Derived Growth Factor Receptor I^ in the Mouse Model. ( 26939110 )
2016
6
Clinical case report: a rare cause of acute kidney failure - tissue is the issue. ( 27253186 )
2016
7
Hyperkalemia and acute kidney failure associated with preoperative uterine artery embolization for a large uterine fibroid: a case report. ( 27799061 )
2016
8
Elevated biomarkers and contrast-induced acute kidney failure: what comes first the chicken or the egg? ( 25684714 )
2015
9
Acute kidney failure associated with anaphylactic shock caused by diclofenac sodium. ( 25899205 )
2015
10
Tuberous sclerosis presenting with acute kidney failure, pyelonephritis, and polycystic kidney disease. ( 25001142 )
2014
11
Successful reversal of acute kidney failure by ultrasound-accelerated thrombolysis of an occluded renal artery. ( 25276140 )
2014
12
Novel presentation of rituximab-induced herpes zoster: urinary retention and acute kidney failure. ( 25079963 )
2014
13
Crohnic kidney disease: recurrent acute kidney failure in a patient with Crohn's disease. ( 25599054 )
2014
14
Older Adults with CKD and Acute Kidney Failure: Do We Know Enough for Critical Shared Decision Making? ( 24262792 )
2014
15
Cardiac catheterization and postoperative acute kidney failure in congenital heart pediatric patients. ( 23780421 )
2013
16
Monitoring of metformin-induced lactic acidosis in a diabetic patient with acute kidney failure and effect of hemodialysis. ( 23149294 )
2013
17
Joint pain, digital necrosis and acute kidney failure in small-vessel autoimmune disease. ( 26019859 )
2013
18
Malignant hypertension with protracted but not definitive oligoanuric acute kidney failure. ( 27293574 )
2013
19
Acute kidney failure with renal carcinomatous lymphangitis secondary to advanced colon cancer. ( 23903432 )
2013
20
New insights in acute kidney failure in the critically ill. ( 22923149 )
2012
21
Female with rash, acute kidney failure and rheumatoid arthritis. ( 23023360 )
2012
22
Acute kidney failure complicating carbon monoxide poisoning. ( 22992968 )
2012
23
Primary renal lymphoma: an uncommon diagnosis for acute kidney failure. ( 26019832 )
2012
24
Renal Replacement Therapy in Acute Kidney Failure due to Rhabdomyolysis. ( 24826338 )
2012
25
Early biomarkers of acute kidney failure after heart angiography or heart surgery in patients with acute coronary syndrome or acute heart failure. ( 22130209 )
2012
26
Renal tubular Fas ligand mediates fratricide in cisplatin-induced acute kidney failure. ( 20811331 )
2011
27
Acute kidney failure in the context of a Tako-Tsubo syndrome. ( 21738255 )
2011
28
Effective use of continuous arteriovenous hemodialysis in a critically ill human immunodeficiency virus-positive patient with acute kidney failure. ( 20622320 )
2010
29
Hemolysis and acute kidney failure. ( 20605299 )
2010
30
Acute kidney failure in neonatal period. ( 19617661 )
2009
31
Acute bacterial pyelonephritis resulting in acute kidney failure: a complication of chronic non-steroidal anti-inflammatory drug use? ( 19335847 )
2009
32
Acute kidney failure in the third trimester of pregnancy. ( 19008026 )
2009
33
Recurrent acute kidney failure due to McArdle disease. ( 19377243 )
2008
34
RIFLE classification of acute kidney failure in intensive care. ( 17639826 )
2007
35
Focus on hepatitis. Low CD4 count + HCV coinfection = acute kidney failure. ( 17366669 )
2006
36
Summaries for patients. Plasma exchange treatment is not effective in treating acute kidney failure caused by multiple myeloma. ( 16330784 )
2005
37
Postpartum acute kidney failure and hyponatremia: a clinical enigma. ( 15473598 )
2004
38
Acute kidney failure: a pediatric experience over 20 years. ( 12197796 )
2002
39
[Acute kidney failure in the course of rhabdomyolysis with hemodialysis in personal material from 1995-1999]. ( 11255648 )
2000
40
[Acute kidney failure. Non-invasive diagnosis of acute kidney failure in operative intensive care patients]. ( 9567152 )
1998
41
Vasculitis with acute kidney failure and torasemide. ( 9863798 )
1998
42
[Plasma myoglobin and continuous hemofiltration in patients with rhabdomyolysis and acute kidney failure]. ( 9297272 )
1997
43
[Urodilatin (INN: ularitide). A new peptide in the treatment of acute kidney failure following liver transplantation]. ( 8702053 )
1996
44
[Experimental models of acute kidney failure]. ( 7569687 )
1995
45
[Acute kidney failure associated with the HELLP syndrome. A case report]. ( 7959159 )
1994
46
Aggressive peritoneal dialysis for treatment of acute kidney failure after neonatal heart transplantation. ( 1576138 )
1992
47
Hyperosmolar nonketotic syndrome associated with rhabdomyolysis and acute kidney failure. ( 2060421 )
1991
48
Dramatic reduction in sandimmune (CyA) dosage may be effective in reversal of severe hyperbilirubinemia and post-transplant acute kidney failure linked to CyA toxicity. ( 3313989 )
1987
49
Acute kidney failure: prerenal, renal, or postrenal? ( 3932406 )
1985
50
Acute kidney failure. ( 13368869 )
1956

Variations for Acute Kidney Failure

Expression for Acute Kidney Failure

Search GEO for disease gene expression data for Acute Kidney Failure.

Pathways for Acute Kidney Failure

Pathways related to Acute Kidney Failure according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.93 ALB EGF HGF

GO Terms for Acute Kidney Failure

Cellular components related to Acute Kidney Failure according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.81 ALB B2M CFH CST3 EGF IL18
2 extracellular region GO:0005576 9.65 ADAMTS13 ALB B2M CFH CST3 EGF
3 endoplasmic reticulum lumen GO:0005788 9.62 ADAMTS13 ALB B2M CST3
4 platelet alpha granule lumen GO:0031093 9.43 ALB EGF HGF
5 extracellular space GO:0005615 9.32 ADAMTS13 ALB B2M CFH CST3 EGF

Biological processes related to Acute Kidney Failure according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 9.54 CST3 MB NPPA
2 platelet degranulation GO:0002576 9.5 ALB EGF HGF
3 response to drug GO:0042493 9.46 B2M CST3 REN SLC22A12
4 phosphatidylinositol-mediated signaling GO:0048015 9.43 EGF HGF PIK3C2A
5 sodium-independent organic anion transport GO:0043252 9.4 ALB SLC22A12
6 phosphatidylinositol phosphorylation GO:0046854 9.13 EGF HGF PIK3C2A
7 cellular protein metabolic process GO:0044267 8.92 ALB B2M CST3 NPPA

Sources for Acute Kidney Failure

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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