MCID: ACT072
MIFTS: 33

Acute Laryngitis

Categories: Respiratory diseases, Infectious diseases

Aliases & Classifications for Acute Laryngitis

MalaCards integrated aliases for Acute Laryngitis:

Name: Acute Laryngitis 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9396
ICD10 32 J04.0
ICD9CM 34 464.0 464.01
NCIt 46 C26688

Summaries for Acute Laryngitis

Disease Ontology : 12 A laryngitis which lasts less than a few days.

MalaCards based summary : Acute Laryngitis is related to laryngitis and chronic laryngitis. An important gene associated with Acute Laryngitis is VSIR (V-Set Immunoregulatory Receptor). The drugs Dexamethasone and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include neutrophil and colon.

Related Diseases for Acute Laryngitis

Diseases in the Laryngitis family:

Chronic Laryngitis Viral Laryngitis
Acute Laryngitis

Diseases related to Acute Laryngitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 laryngitis 31.7 ATP12A ATP4A
2 chronic laryngitis 28.9 ATP12A ATP4A
3 viral laryngitis 11.0
4 laryngotracheitis 10.3
5 tracheitis 10.1
6 fungal esophagitis 9.9 ATP12A ATP4A
7 bladder calculus 9.9 ATP12A ATP4A
8 gastrointestinal neuroendocrine benign tumor 9.9 ATP12A ATP4A
9 gastric neuroendocrine neoplasm 9.9 ATP12A ATP4A
10 neonatal candidiasis 9.9 ATP12A ATP4A
11 photoallergic dermatitis 9.9 ATP12A ATP4A
12 squamous papillomatosis 9.9 ATP12A ATP4A
13 gastroduodenal crohn's disease 9.8 ATP12A ATP4A
14 toxic megacolon 9.8 ATP12A ATP4A
15 aspiration pneumonitis 9.8 ATP12A ATP4A
16 gastric antral vascular ectasia 9.8 ATP12A ATP4A
17 esophageal candidiasis 9.8 ATP12A ATP4A
18 postsurgical hypothyroidism 9.8 ATP12A ATP4A
19 rumination disorder 9.8 ATP12A ATP4A
20 laryngeal disease 9.8 ATP12A ATP4A
21 duodenitis 9.8 ATP12A ATP4A
22 congenital disorder of deglycosylation 9.8 ATP12A ATP4A
23 bile reflux 9.8 ATP12A ATP4A
24 granulomatous gastritis 9.8 ATP12A ATP4A
25 active peptic ulcer disease 9.8 ATP12A ATP4A
26 dyskinesia of esophagus 9.8 ATP12A ATP4A
27 ischemic neuropathy 9.8 ATP12A ATP4A
28 anismus 9.8 ATP12A ATP4A
29 capillary disease 9.8 ATP12A ATP4A
30 peptic esophagitis 9.8 ATP12A ATP4A
31 duodenal disease 9.8 ATP12A ATP4A
32 hernia, hiatus 9.8 ATP12A ATP4A
33 esophageal atresia/tracheoesophageal fistula 9.8 ATP12A ATP4A
34 laryngeal tuberculosis 9.8 ATP12A ATP4A
35 lymphocytic colitis 9.8 ATP12A ATP4A
36 chronic intestinal vascular insufficiency 9.8 ATP12A ATP4A
37 clostridium difficile colitis 9.8 ATP12A ATP4A
38 lower urinary tract calculus 9.8 ATP12A ATP4A
39 diarrhea 1, secretory chloride, congenital 9.8 ATP12A ATP4A
40 polyposis, skin pigmentation, alopecia, and fingernail changes 9.8 ATP12A ATP4A
41 aspiration pneumonia 9.8 ATP12A ATP4A
42 esophageal varix 9.8 ATP12A ATP4A
43 eosinophilic gastritis 9.8 ATP12A ATP4A
44 myopathy, x-linked, with excessive autophagy 9.7 ATP12A ATP4A
45 esophagus adenocarcinoma 9.7 ATP12A ATP4A
46 jejunoileitis 9.7 ATP12A ATP4A
47 pancreatic steatorrhea 9.7 ATP12A ATP4A
48 pneumatosis cystoides intestinalis 9.7 ATP12A ATP4A
49 superior mesenteric artery syndrome 9.7 ATP12A ATP4A
50 functional gastric disease 9.7 ATP12A ATP4A

Graphical network of the top 20 diseases related to Acute Laryngitis:



Diseases related to Acute Laryngitis

Symptoms & Phenotypes for Acute Laryngitis

Drugs & Therapeutics for Acute Laryngitis

Drugs for Acute Laryngitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 86)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
2
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
3
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
4 Racepinephrine Approved Phase 4 329-65-7
5
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
6
Meloxicam Approved, Vet_approved Phase 4 71125-38-7 54677470 5281106
7
Esomeprazole Approved, Investigational Phase 4 161796-78-7, 119141-88-7 9579578 4594
8
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
9
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
10
Dexlansoprazole Approved, Investigational Phase 4 138530-94-6, 103577-45-3 9578005
11
Salmeterol xinafoate Phase 4 94749-08-3 56801
12 Dexamethasone acetate Phase 4 1177-87-3
13
Fluticasone Phase 4,Phase 3 80474-14-2, 90566-53-3 22833648 62924
14 glucocorticoids Phase 4,Phase 3
15
protease inhibitors Phase 4
16 Respiratory System Agents Phase 4,Phase 3
17 Fluticasone Propionate, Salmeterol Xinafoate Drug Combination Phase 4
18 Adrenergic Agents Phase 4,Phase 2,Phase 3
19 Adrenergic Agonists Phase 4
20 Adrenergic beta-2 Receptor Agonists Phase 4
21 Adrenergic beta-Agonists Phase 4
22 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
23 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
24 HIV Protease Inhibitors Phase 4
25 Hormone Antagonists Phase 4,Phase 3
26 Dermatologic Agents Phase 4,Phase 3
27 Hormones Phase 4,Phase 3
28 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3
29 Anti-Allergic Agents Phase 4,Phase 3
30 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
31 Anti-Asthmatic Agents Phase 4,Phase 3
32 Epinephryl borate Phase 4
33 Antiemetics Phase 4,Phase 3
34 Anti-Inflammatory Agents Phase 4,Phase 3
35 Proton pump inhibitors Phase 4,Phase 2,Phase 3
36 Antineoplastic Agents, Hormonal Phase 4,Phase 3
37 BB 1101 Phase 4
38 Autonomic Agents Phase 4,Phase 3
39 Bronchodilator Agents Phase 4,Phase 3
40 Analgesics Phase 4,Phase 2,Phase 3
41 Cyclooxygenase Inhibitors Phase 4
42 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3
43 Antacids Phase 4,Phase 2,Phase 3
44 Anti-Inflammatory Agents, Non-Steroidal Phase 4
45 Anti-Ulcer Agents Phase 4,Phase 2,Phase 3
46 Antirheumatic Agents Phase 4
47 Adrenergic alpha-Agonists Phase 4
48 Mydriatics Phase 4
49 Vasoconstrictor Agents Phase 4
50
Rabeprazole Approved, Investigational Phase 2, Phase 3 117976-89-3 5029

Interventional clinical trials:

(show all 25)

# Name Status NCT ID Phase Drugs
1 Study to Assess the Incidence of Local Oropharyngeal and Laryngeal Adverse Effects of Advair DISKUS 250/50 Mcg BID Unknown status NCT00235053 Phase 4 fluticasone/salmeterol DISKUS 250/50
2 Chronic Posterior Laryngitis With Suspected Laryngopharyngeal Reflux Completed NCT00628667 Phase 4 Esomeprazole;Placebo
3 Efficacy and Safety of Meloxicam Suspension Versus Diclofenac Suspension or Nimesulide Suspension in Patients With a Diagnosis of Acute, Non-bacterial Pharyngitis, Pharyngotonsillitis or Laryngitis Completed NCT02229747 Phase 4 Meloxicam;Diclofenac;Nimesulide
4 Quality of Life Validation in Laryngitis Completed NCT00641264 Phase 4 Omeprazole
5 Community Care for Croup (RCT) Completed NCT01042145 Phase 4 Prednisone;Dexamethasone
6 The Effect and Safety of Low Dose Nebulized Epinephrine in Croup Recruiting NCT01664507 Phase 4 conventional dose epinephrine;low dose epinephrine
7 Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux Terminated NCT00369265 Phase 4 Lansoprazole
8 Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment Completed NCT00204698 Phase 2, Phase 3 Aciphex
9 CLEARI (Clinical Efficacy Assessment on Recurrent Upper-Respiratory Tract Infections) Study Completed NCT01948856 Phase 3 J022X ST;Placebo
10 Treatment of Chronic Laryngitis With Amitriptyline Suspended NCT02552225 Phase 2, Phase 3 Amitriptyline
11 Trial of the Treatment of Chronic Laryngitis With Amitryptiline Terminated NCT02434523 Phase 2, Phase 3 Amitriptyline
12 Management of Recurrent Croup Terminated NCT01748162 Phase 3 Fluticasone;Prednisolone IF needed
13 Efficacy of Nebulized Beclomethasone Dipropionate (BDP) in the Treatment of Moderate Croup Terminated NCT00938353 Phase 3 beclomethasone dipropionate suspension for nebulisation 800 mcg/2 ml;Placebo solution for nebulisation 2 ml
14 Treatment of Acute Tracheitis and Laryngitis With Essential Oils of Aromatic Plants Completed NCT00611390 Phase 1, Phase 2
15 Comparing Different Ways of Delivering Humidity to Children With Croup Completed NCT00230841 Phase 2
16 Positive Predictive Value of the Dx-pH Probe for Predicting PPI Response in LPR Unknown status NCT01755221
17 Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children Unknown status NCT02056379 Budesonide;Dexamethasone
18 Non Interventional Study (NIS) Regarding the Application of Ectoin Mund- & Rachenspray in Patients With Acute Laryngitis and/or Acute Pharyngitis Completed NCT02160912
19 Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis Completed NCT01806220
20 Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis Completed NCT01389401 omeprazole
21 Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese Patients Completed NCT00517114 Rabeprazole 20mg twice daily
22 Inter-rater Reliability of the Reflux Finding Score Among Gastroenterologists Completed NCT02048449
23 Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media) Completed NCT01406275 Amoxicillin and clavulanate
24 The Effect of Zinc Acetate Lozenges on the Rate of Recovery From the Common Cold Enrolling by invitation NCT03309995
25 A Cluster Controlled Trial Comparing Three Methods of Disseminating Practice Guidelines for Children With Croup Terminated NCT00147849

Search NIH Clinical Center for Acute Laryngitis

Genetic Tests for Acute Laryngitis

Anatomical Context for Acute Laryngitis

MalaCards organs/tissues related to Acute Laryngitis:

38
Neutrophil, Colon

Publications for Acute Laryngitis

Articles related to Acute Laryngitis:

(show all 33)
# Title Authors Year
1
Antibiotics for acute laryngitis in adults. ( 26002823 )
2015
2
Antibiotics for acute laryngitis in adults. ( 23543536 )
2013
3
Acute laryngitis superimposed on chronic laryngitis. ( 23460211 )
2013
4
Prospective study of rapid relief provided by C1 esterase inhibitor in emergency treatment of acute laryngeal attacks in hereditary angioedema. ( 20635155 )
2010
5
Superior laryngeal neuralgia after acute laryngitis and treatment with a single injection of a local anesthetic. ( 17875862 )
2007
6
Antibiotics for acute laryngitis in adults. ( 17443555 )
2007
7
Antibiotics for acute laryngitis in adults. ( 15674965 )
2005
8
Antibiotics for acute laryngitis in adults. ( 16035684 )
2005
9
Effect of meteorological parameters on acute laryngitis in adults. ( 12403130 )
2002
10
Acute laryngitis in a professional singer. ( 11480296 )
2001
11
Acute laryngitis. ( 11933444 )
2000
12
Acute laryngitis. ( 10935296 )
2000
13
Acute laryngeal oedema and the yellow nail syndrome. ( 16351992 )
2000
14
Acute laryngitis in the rat induced by Moraxella catarrhalis and Bordetella pertussis: number of neutrophils, dendritic cells, and T and B lymphocytes accumulating during infection in the laryngeal mucosa strongly differs in adjacent locations. ( 10590036 )
1999
15
Some aerodynamic and acoustic characteristics of acute laryngitis. ( 9297681 )
1997
16
Moraxella catarrhalis in acute laryngitis: infection or colonization? ( 8769627 )
1996
17
Erythromycin in acute laryngitis in adults. ( 8457123 )
1993
18
Acute laryngitis in adults: results of erythromycin treatment. ( 1632252 )
1992
19
Elevated creatine phosphokinase and creatine phosphokinase-MB in acute laryngitis. ( 2046207 )
1991
20
Acute laryngitis in adults: diagnosis, etiology, treatment. ( 3144113 )
1988
21
Acute laryngeal obstruction in junctional epidermolysis bullosa. ( 3658840 )
1987
22
Inefficacy of penicillin V in acute laryngitis in adults. Evaluation from results of double-blind study. ( 3918495 )
1985
23
Acute laryngitis associated with rotavirus gastroenteritis. ( 6631034 )
1983
24
High isolation rate of Branhamella catarrhalis from the nasopharynx in adults with acute laryngitis. ( 7006061 )
1980
25
Acute laryngeal obstruction in Felty's syndrome. ( 701984 )
1978
26
Radiological features of acute laryngitis in infancy. ( 4636301 )
1972
27
The treatment with antiserum of acute laryngitis caused by Hemophilus influenzae. ( 21007906 )
1945
28
Pulsus Paradoxus in Acute Laryngitis. ( 20755517 )
1895
29
PULSUS PARADOXUS in ACUTE LARYNGITIS. ( 20754305 )
1893
30
Clinical Lecture on Acute Laryngitis. ( 20744011 )
1862
31
Case of Acute Laryngitis, with Observations. ( 20794577 )
1849
32
Case of Acute Laryngitis: with Remarks on Dr. Wardell's Cases of Spasma Glottidis. ( 20794401 )
1848
33
Case of acute laryngitis in which tracheotomy was performed. ( 21379785 )
1841

Variations for Acute Laryngitis

Expression for Acute Laryngitis

Search GEO for disease gene expression data for Acute Laryngitis.

Pathways for Acute Laryngitis

GO Terms for Acute Laryngitis

Biological processes related to Acute Laryngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium ion transport GO:0006813 9.26 ATP12A ATP4A
2 sodium ion transport GO:0006814 9.16 ATP12A ATP4A
3 proton transport GO:0015992 8.96 ATP12A ATP4A
4 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.62 ATP12A ATP4A

Molecular functions related to Acute Laryngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 hydrogen:potassium-exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Acute Laryngitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....