MCID: ACT103
MIFTS: 49

Acute Lymphoblastic Leukemia, Childhood malady

Immune category

Summaries for Acute Lymphoblastic Leukemia, Childhood

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33MalaCards
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MalaCards: Acute Lymphoblastic Leukemia, Childhood, also known as childhood acute lymphoblastic leukemia, is related to acute leukemia and lymphoblastic lymphoma. An important gene associated with Acute Lymphoblastic Leukemia, Childhood is CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)), and among its related pathways are GPCR Pathway and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways. The compounds estrogen and sodium bisulfite have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, spleen and skeletal muscle, and related mouse phenotypes are pigmentation and renal/urinary system.

Aliases & Classifications for Acute Lymphoblastic Leukemia, Childhood

Sources:
43NIH Rare Diseases, 31LifeMap Discovery™, 45Novoseek
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Immune


Aliases & Descriptions:

acute lymphoblastic leukemia, childhood 43 31
childhood acute lymphoblastic leukemia 43
lymphoblastic leukemia acute childhood 45


Related Diseases for Acute Lymphoblastic Leukemia, Childhood

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Acute Lymphoblastic Leukemia, Childhood via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 132)
idRelated DiseaseScoreTop Affiliating Genes
1acute leukemia32.3KMT2A, ETV6, CDKN2B, CDKN2C, TAL1
2lymphoblastic lymphoma31.0CDKN2B, TAL1, KMT2A
3precursor t-cell acute lymphoblastic leukemia30.5TAL1, IKZF1, CDKN1B, CDKN2B, CDKN2A, ETV6
4anaplastic oligodendroglioma30.3CDKN2C, CDKN2B, CDKN2A, MDM2
5precursor b-cell acute lymphoblastic leukemia30.3ETV6, CDKN2A, CDKN2B, KMT2A
6acute t cell leukemia10.8
7t-cell leukemia10.8
8central nervous system leukemia10.6
9testicular leukemia10.5
10testicular disease10.5
11glucocorticoid resistance10.5
12leukemia, acute lymphoblastic 210.5
13acute myeloid leukemia10.5
14nijmegen breakage syndrome10.5
15n syndrome10.5
16acute myeloid leukemia, childhood10.5
17acute non lymphoblastic leukemia10.5
18hypercalcemia10.4
19bone marrow necrosis10.4
20hypoxia10.4
21insulin resistance10.4
22lymphoid leukemia10.2
23childhood oligodendroglioma10.2
24osteonecrosis10.2
25meningoencephalitis10.2
26spindle cell carcinoma10.2
27hypoglycemia10.2
28siderosis10.2
29nephrocalcinosis10.2
30adult syndrome10.2
31mucoepidermoid carcinoma10.2
32acinar cell carcinoma10.2
333-m syndrome10.2
34wilms tumor10.2
35breast cancer, childhood10.2
36hodgkin lymphoma, childhood10.2
37triploidy10.2
38cytomegalovirus retinitis10.2
39demodicidosis10.2
40fasting hypoglycemia10.2
41growth hormone deficiency10.2
42lymphomatoid granulomatosis10.2
43soft tissue sarcoma childhood10.2
44stenotrophomonas maltophilia10.2
45tetraploidy10.2
46cardiovascular disease risk factor10.2
47mannose-binding lectin deficiency10.2
48leukemia, acute pre-b-cell10.2
493-m syndrome 210.2
50memory impairment10.2

Graphical network of the top 20 diseases related to Acute Lymphoblastic Leukemia, Childhood:



Diseases related to acute lymphoblastic leukemia, childhood

Clinical Features for Acute Lymphoblastic Leukemia, Childhood

Drugs & Therapeutics for Acute Lymphoblastic Leukemia, Childhood

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 31LifeMap Discovery™, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Acute Lymphoblastic Leukemia, Childhood

Drug clinical trials:

Search ClinicalTrials for Acute Lymphoblastic Leukemia, Childhood

Search NIH Clinical Center for Acute Lymphoblastic Leukemia, Childhood

Search CenterWatch for Acute Lymphoblastic Leukemia, Childhood

Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Stem-cell-based therapeutic approaches for Acute Lymphoblastic Leukemia, Childhood:
Hematopoietic stem cells for treatment of hematologic malignancies
Embryonic/Adult Cultured Cells Related to Acute Lymphoblastic Leukemia, Childhood:
Bone marrow-derived hematopoietic stem cells

Genetic Tests for Acute Lymphoblastic Leukemia, Childhood

Anatomical Context for Acute Lymphoblastic Leukemia, Childhood

Sources:
33MalaCards
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MalaCards organs/tissues related to Acute Lymphoblastic Leukemia, Childhood:

33
Bone marrow, Spleen, Skeletal muscle, Liver, Lung, Breast, Myeloid, T cells, B lymphoblasts, B cells, Endothelial, Tongue, Fetal liver, Fetal lung

Animal Models for Acute Lymphoblastic Leukemia, Childhood or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Acute Lymphoblastic Leukemia, Childhood:

37 (show all 22)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000118610.3TAL1
2MP:000536710.3KMT2A
3MP:00053809.5KMT2A, INS
4MP:00036319.5INS, KMT2A
5MP:00053889.0CDKN2C, IKZF1, CEBPE, CDKN1B
6MP:00053799.0CDKN2B, CDKN2A, CDKN2C, ETV6, CDKN1B
7MP:00053908.6TAL1, ARID5B, CEBPE, KMT2A
8MP:00053898.3ARID5B, CDKN2A, CDKN2B, CDKN1B, KMT2A, CDKN2C
9MP:00053697.9MDM2, CDKN2A, INS, LEP, ARID5B
10MP:00030127.9KMT2A, INS, CDKN1B, CDKN2B, ETV6, CDKN2A
11MP:00053707.7KMT2A, MDM2, LEP, IKZF1, INS, CDKN1B
12MP:00053767.4KMT2A, CDKN2C, INS, TAL1, LEP, ARID5B
13MP:00053857.3MDM2, TAL1, CDKN2C, INS, CDKN1B, ETV6
14MP:00020067.3MDM2, ETV6, CDKN2A, CDKN2B, CDKN1B, CDKN2C
15MP:00053867.0INS, MDM2, CDKN2A, CDKN1B, CDKN2C, KMT2A
16MP:00053816.6CEBPE, INS, CDKN1B, CDKN2A, ETV6, ARID5B
17MP:00107716.6CEBPE, KMT2A, TAL1, INS, CDKN2C, CDKN1B
18MP:00053786.0LEP, TAL1, CDKN2A, CDKN2C, INS, CDKN1B
19MP:00053975.4KMT2A, CEBPE, TAL1, LEP, IKZF1, INS
20MP:00053845.3MDM2, ARID5B, CDKN2A, CDKN2B, CDKN1B, ETV6
21MP:00053875.1ETV6, IKZF1, CDKN2C, TAL1, LEP, CDKN1B
22MP:00107685.1CDKN1B, MDM2, ARID5B, MTAP, ETV6, CDKN2A

Publications for Acute Lymphoblastic Leukemia, Childhood

Sources:
51PubMed
See all sources

Articles related to Acute Lymphoblastic Leukemia, Childhood:

(show top 50)    (show all 589)
idTitleAuthorsYear
1
Clinical characteristics and treatment outcome of childhood acute lymphoblastic leukemia in Saudi Arabia: a multi-institutional retrospective national collaborative study. (23940019)
2014
2
Zebularine induces chemosensitization to methotrexate and efficiently decreases AhR gene methylation in childhood acute lymphoblastic leukemia cells. (24052107)
2014
3
Childhood high-risk acute lymphoblastic leukemia in first remission: results after chemotherapy or transplant from the AIEOP ALL 2000 study. (24415536)
2014
4
RE: "Lack of prognostic significance of absolute lymphocyte count after intensive induction therapy in childhood acute lymphoblastic leukemia" (PBC-12-0049.R2). (23997034)
2014
5
Focal Cranial Hyperostosis From Meningioma: A Complication From Previous Radiation Treatment for Childhood T-Cell Acute Lymphoblastic Leukemia. (23459379)
2013
6
FLT3 mutations in patients with childhood acute lymphoblastic leukemia (ALL). (23335073)
2013
7
Long-term decline in intelligence among adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiation. (23744583)
2013
8
Correspondence: The preventive role of MTR A2756G polymorphisms in childhood acute lymphoblastic leukemia remains inconclusive. (24303783)
2013
9
A 50-year journey to cure childhood acute lymphoblastic leukemia. (23953334)
2013
10
Key treatment questions in childhood acute lymphoblastic leukemia: results in 5 consecutive trials performed by the ALL-BFM study group from 1981 to 2000. (23700060)
2013
11
Bortezomib with chemotherapy is highly active in advanced B-precursor acute lymphoblastic leukemia: Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Study. (22653976)
2012
12
Differential miRNA expression in childhood acute lymphoblastic leukemia and association with clinical and biological features. (22099053)
2012
13
Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia. (22076464)
2012
14
Lack of association between MTHFR C677T and A1298C polymorphisms and risk of childhood acute lymphoblastic leukemia in the Kurdish population from Western Iran. (22017305)
2012
15
Mucoepidermoid carcinoma of the parotid gland in childhood survivor of acute lymphoblastic leukemia with need of radiotherapy for treatment and review of the literature. (22568803)
2012
16
Nijmegen breakage syndrome (NBS) as a risk factor for CNS involvement in childhood acute lymphoblastic leukemia. (21557461)
2011
17
ARID5B SNP rs10821936 is associated with risk of childhood acute lymphoblastic leukemia in blacks and contributes to racial differences in leukemia incidence. (20054350)
2010
18
Prognostic significance of TEL/AML1 rearrangement and its additional genetic changes in Korean childhood precursor B-acute lymphoblastic leukemia]. (20197715)
2010
19
Relation of HLA-DRB1*15 with pathogenesis in 162 childhood cases of acute lymphoblastic leukemia]. (20030936)
2009
20
Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia. (18923441)
2009
21
Garlic compounds selectively kill childhood pre-B acute lymphoblastic leukemia cells in vitro without reducing T-cell function: Potential therapeutic use in the treatment of ALL. (19707437)
2008
22
ZAP-70 is highly expressed in most cases of childhood pre-B cell acute lymphoblastic leukemia. (18333847)
2008
23
Successful treatment of acanthamoeba meningoencephalitis during induction therapy of childhood acute lymphoblastic leukemia. (18253958)
2008
24
Prognostic role of the reduced folate carrier, the major membrane transporter for methotrexate, in childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. (17255265)
2007
25
Expression of apoptosis regulators Bcl-2 and Bax in childhood acute lymphoblastic leukemia. (17364991)
2007
26
Hypoxia-mediated fenretinide (4-HPR) resistance in childhood acute lymphoblastic leukemia cells. (16520989)
2006
27
The prognostic significance of CDKN2A, CDKN2B and MTAP inactivation in B-lineage acute lymphoblastic leukemia of childhood. Results of the EORTC studies 58881 and 58951. (16818274)
2006
28
MLL gene rearrangements have no direct impact on Ara-C sensitivity in infant acute lymphoblastic leukemia and childhood M4/M5 acute myeloid leukemia. (16307022)
2006
29
GSTP1 and MDR1 genotypes and central nervous system relapse in childhood acute lymphoblastic leukemia. (15717687)
2005
30
Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia. (15899912)
2005
31
Second malignant neoplasms in childhood acute lymphoblastic leukemia: primitive neuroectodermal tumor of the chest wall with germline p53 mutation as a second malignant neoplasm. (15114597)
2004
32
Multiple drug resistance protein (MDR-1), multidrug resistance-related protein (MRP) and lung resistance protein (LRP) gene expression in childhood acute lymphoblastic leukemia. (15543372)
2004
33
Growth hormone deficiency predicts cardiovascular risk in young adults treated for acute lymphoblastic leukemia in childhood. (15472198)
2004
34
Reassessment of loss of heterozygosity within MLL in childhood acute lymphoblastic leukemia. (12732503)
2003
35
Assessment of clonal stability of minimal residual disease targets between 1st and 2nd relapse of childhood precursor B-cell acute lymphoblastic leukemia. (12857551)
2003
36
Modification of topoisomerase genes copy number in newly diagnosed childhood acute lymphoblastic leukemia. (12646941)
2003
37
Autologous bone marrow transplantation for childhood acute lymphoblastic leukemia: a novel combined approach consisting of ex vivo marrow purging, modulation of multi-drug resistance, induction of autograft vs leukemia effect, and post-transplant immuno- and chemotherapy (PTIC). (11281383)
2001
38
Initial P-glycoprotein expression in childhood acute lymphoblastic leukemia: no evidence of prognostic impact in follow-up. (11205837)
2001
39
Parotid mucoepidermoid carcinoma following chemotherapy for childhood acute lymphoblastic leukemia. (11293291)
2001
40
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia. (10764140)
2000
41
Clinical significance of P-glycoprotein (P-gp) expression in childhood acute lymphoblastic leukemia. Results of a 6-year prospective study. (10500775)
1999
42
Bone and mineral abnormalities in childhood acute lymphoblastic leukemia: influence of disease, drugs and nutrition. (9876475)
1998
43
Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia. (9664088)
1998
44
Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia. (9108419)
1997
45
Deoxycytidine kinase mRNA expression in childhood acute lymphoblastic leukemia. (9215616)
1997
46
Biallelic alterations of both ETV6 and CDKN1B genes in a t(12;21) childhood acute lymphoblastic leukemia case. (8653712)
1996
47
Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene. (7888679)
1995
48
Expression of myeloperoxidase mRNA by leukemic cells from childhood acute lymphoblastic leukemia. (8394481)
1993
49
Clinical features and outcome of T-cell acute lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus: a Pediatric Oncology Group study. (8471769)
1993
50
Multiple rearranged immunoglobulin genes in childhood acute lymphoblastic leukemia of precursor B-cell origin. (1909409)
1991

Genetic Variations for Acute Lymphoblastic Leukemia, Childhood

Expression for genes affiliated with Acute Lymphoblastic Leukemia, Childhood

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Acute Lymphoblastic Leukemia, Childhood

Search GEO for disease gene expression data for Acute Lymphoblastic Leukemia, Childhood.

Pathways for genes affiliated with Acute Lymphoblastic Leukemia, Childhood

Sources:
52QIAGEN, 53R&D Systems, 12EMD Millipore, 38NCBI BioSystems Database, 54Reactome, 30KEGG, 4Cell Signaling Technology
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Pathways related to Acute Lymphoblastic Leukemia, Childhood according to GeneCards/GeneDecks:

(show all 19)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.2CDKN2B
2
Hide members
10.2CDKN1B
39.8MDM2, CDKN2A
49.8MDM2, CDKN2A
59.8CDKN1B, MDM2
6
Cell cycle Cell cycle (generic schema)
Hide members
9.6CDKN2B, CDKN2A, CDKN1B
79.5CDKN2A, MDM2, CDKN1B
8
Hide members
9.5MDM2, CDKN2A, CDKN1B
9
Hide members
9.5MDM2, CDKN2A, CDKN1B
10
Hide members
9.5CDKN1B, MDM2, CDKN2A
11
Hide members
9.4CDKN2B, CDKN1B, CDKN2C, CDKN2A
129.3MDM2, CDKN2A, CDKN1B, CDKN2B
139.3CDKN1B, CDKN2B, MDM2, CDKN2A
14
Hide members
9.3CDKN2C, CDKN1B, CDKN2A, MDM2
15
Hide members
9.3CDKN1B, CDKN2C, CDKN2A, MDM2
16
Hide members
9.0CDKN2A, CDKN2B, CDKN1B, CDKN2C, MDM2
17
Hide members
8.6MDM2, CDKN2A, CDKN2B, CDKN1B, CDKN2C, INS
188.6INS, MDM2, CDKN1B, KMT2A, CDKN2A
198.0CEBPE, KMT2A, CDKN2C, CDKN1B, ETV6, MDM2

Compounds for genes affiliated with Acute Lymphoblastic Leukemia, Childhood

Sources:
45Novoseek, 11DrugBank, 50PharmGKB, 29IUPHAR, 24HMDB, 60Tocris Bioscience, 2BitterDB
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Compounds related to Acute Lymphoblastic Leukemia, Childhood according to GeneCards/GeneDecks:

(show top 50)    (show all 52)
idCompoundScoreTop Affiliating Genes
1estrogen4510.4KMT2A
2sodium bisulfite4510.2CDKN2B, CDKN2A
3fatty acid4510.1CDKN2A, CDKN1B
4exenatide45 1111.1LEP, INS
55-methylthioadenosine4510.1CDKN2B, MTAP, CDKN2A
67,12-dimethylbenz(a)anthracene4510.1MDM2, CDKN2A
7pramlintide45 1111.0LEP, INS
8sibutramine45 1111.0LEP, INS
9beta-hydroxybutyrate4510.0INS, LEP
10cytarabine45 50 1112.0CDKN2A, CDKN1B, CDKN2B
11acipimox45 2911.0LEP, INS
12flavopiridol45 1110.9MDM2, CDKN2A, CDKN1B
13nucleoside459.9CDKN1B, MTAP, MDM2
14intralipid459.8INS, LEP
155-methylcytosine45 2410.8CDKN2B, CDKN2A
16nash459.8INS, LEP
17camptothecin45 60 1111.8CDKN1B, CDKN2A, MDM2
18adenine45 11 2411.8CDKN2A, MTAP, LEP
19mg 13245 6010.7MDM2, CDKN1B, CDKN2A
20telmisartan45 29 1111.7INS, LEP
21troglitazone45 29 60 1112.7INS, CDKN1B, LEP
22vincristine45 50 1111.7CDKN2A, MDM2, KMT2A
23p003459.6LEP, CDKN2B, MDM2, CDKN1B
24pd 98,059459.6MDM2, CDKN2B, CDKN1B, LEP
255-aza-2deoxycytidine459.5MDM2, CDKN2B, KMT2A, CDKN2A
26paraffin459.5CDKN2A, LEP, MDM2, CDKN1B
27p00001459.4KMT2A, MDM2, CDKN1B, CDKN2A
28etoposide45 50 60 1112.4TAL1, CDKN1B, MDM2, KMT2A
29rapamycin459.4MDM2, LEP, INS, CDKN1B
30ly294002459.4INS, MDM2, LEP, CDKN1B
31wortmannin459.4INS, CDKN1B, MDM2, LEP
32doxorubicin45 50 1111.4KMT2A, CDKN1B, MDM2, CDKN2A
33actinomycin d459.4CDKN1B, KMT2A, CDKN2A, MDM2
34cisplatin45 50 60 1112.3LEP, CDKN1B, CDKN2A, MDM2
35genistein45 29 60 2 11 2414.3CDKN1B, MDM2, KMT2A, CDKN2A
36imatinib45 50 1111.3MDM2, ETV6, CDKN1B
37testosterone45 60 11 2412.1LEP, INS, CDKN2A, MDM2, CDKN1B
38oligonucleotide459.1TAL1, KMT2A, MDM2, CDKN2A, CDKN1B
39agar459.0CDKN1B, ETV6, CDKN2A, MTAP, MDM2
40progesterone45 60 29 11 2413.0IKZF1, LEP, CDKN1B, CDKN2A, MDM2
41dexamethasone45 50 29 1112.0IKZF1, INS, CDKN1B, CDKN2A, MDM2
42alanine458.9MDM2, CDKN2A, INS, IKZF1, CDKN1B
43leucine458.8IKZF1, CDKN2A, CDKN1B, KMT2A
44vegf458.7CDKN1B, MDM2, LEP, CDKN2A, ETV6, TAL1
45threonine458.7CDKN2C, CDKN1B, CDKN2B, CDKN2A, MTAP, MDM2
46arginine458.6LEP, KMT2A, CDKN2A, INS, MDM2, CDKN1B
47retinoic acid45 249.6CDKN2B, CDKN1B, TAL1, KMT2A, ETV6, CDKN2A
48methotrexate45 50 1110.2LEP, ARID5B, MTAP, CDKN2A, MDM2, CDKN2B
49atp45 299.2IKZF1, CDKN1B, KMT2A, MTAP, CDKN2A
50serine457.9KMT2A, CDKN2C, MDM2, CDKN2A, LEP, CDKN2B

GO Terms for genes affiliated with Acute Lymphoblastic Leukemia, Childhood

Sources:
16Gene Ontology
See all sources

Cellular components related to Acute Lymphoblastic Leukemia, Childhood according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleusGO:0056345.5CEBPE, ARID5B, MTAP, ETV6, CDKN2A, CDKN2B

Biological processes related to Acute Lymphoblastic Leukemia, Childhood according to GeneCards/GeneDecks:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1megakaryocyte differentiationGO:03021910.2TAL1, CDKN2B
2cellular response to antibioticGO:07123610.0CDKN1B, MDM2
3positive regulation of insulin receptor signaling pathwayGO:0466289.9INS, LEP
4regulation of cyclin-dependent protein serine/threonine kinase activityGO:0000799.9CDKN2C, CDKN1B, CDKN2B
5negative regulation of cyclin-dependent protein serine/threonine kinase activityGO:0457369.9CDKN2A, CDKN1B
6negative regulation of cell growthGO:0303089.8CDKN2C, CDKN1B, CDKN2A
7protein destabilizationGO:0316489.7MDM2, CDKN2A
8embryonic hemopoiesisGO:0351629.7KMT2A, TAL1
9negative regulation of phosphorylationGO:0423269.7CDKN2C, CDKN1B, CDKN2B, CDKN2A
10cell cycle arrestGO:0070509.7CDKN2A, CDKN2B, CDKN1B, CDKN2C
11mitotic cell cycleGO:0002789.5CDKN2A, CDKN2B, CDKN1B, CDKN2C
12adipose tissue developmentGO:0606129.3LEP, ARID5B
13positive regulation of cell proliferationGO:0082849.1MDM2, CDKN1B, INS, LEP
14negative regulation of cell proliferationGO:0082859.1CDKN2A, CDKN2B, CDKN1B, CDKN2C, KMT2A
15positive regulation of transcription from RNA polymerase II promoterGO:0459448.8CDKN2A, CDKN2B, IKZF1, TAL1, KMT2A
16negative regulation of transcription, DNA-dependentGO:0458928.4CDKN1B, CDKN2A, ARID5B, MDM2

Molecular functions related to Acute Lymphoblastic Leukemia, Childhood according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein serine/threonine kinase inhibitor activityGO:0048619.4CDKN2B, CDKN2C, CDKN1B, CDKN2A
2transcription regulatory region DNA bindingGO:0442128.9KMT2A, TAL1, ARID5B
3sequence-specific DNA binding transcription factor activityGO:0037007.8CEBPE, ETV6, IKZF1, TAL1, KMT2A
4protein bindingGO:0055156.3CDKN2C, CDKN2B, TAL1, KMT2A, INS, CDKN2A

Products for genes affiliated with Acute Lymphoblastic Leukemia, Childhood

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Sources for Acute Lymphoblastic Leukemia, Childhood

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet