MCID: ACT103
MIFTS: 41

Acute Lymphoblastic Leukemia, Childhood malady

Categories: Rare diseases, Cancer diseases, Immune diseases

Aliases & Classifications for Acute Lymphoblastic Leukemia, Childhood

Aliases & Descriptions for Acute Lymphoblastic Leukemia, Childhood:

Name: Acute Lymphoblastic Leukemia, Childhood 38
Childhood Acute Lymphoblastic Leukemia 12 50 14
Childhood Acute Lymphocytic Leukemia 12 50 14
Pediatric Acute Lymphoblastic Leukemia 50
Lymphoblastic Leukemia Acute Childhood 52
Leukemia, Lymphocytic, Acute, L1 69
Childhood All 50

Classifications:



External Ids:

Disease Ontology 12 DOID:0080144
NCIt 47 C3168

Summaries for Acute Lymphoblastic Leukemia, Childhood

NIH Rare Diseases : 50 childhood acute lymphoblastic leukemia (all) is a type of cancer of the blood and bone marrow, and the most common type of cancer in children. in children with this condition, too many stem cells made by the bone marrow become lymphoblasts, b lymphocytes, or t lymphocytes. these cells do not function normally and have trouble fighting off infections. signs and symptoms may include fever; easy bruising or bleeding; bone or joint pain; painless lumps in the neck, underarm, stomach, or groin; weakness; fatigue; and/or loss of appetite. treatment depends on several factors and may include combination chemotherapy, targeted therapy, and/or stem cell transplant. last updated: 4/20/2015

MalaCards based summary : Acute Lymphoblastic Leukemia, Childhood, also known as childhood acute lymphoblastic leukemia, is related to b-cell childhood acute lymphoblastic leukemia and t-cell childhood acute lymphocytic leukemia. An important gene associated with Acute Lymphoblastic Leukemia, Childhood is ETV6 (ETS Variant 6), and among its related pathways/superpathways are One carbon pool by folate and Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex. The drugs Asparaginase and Cytarabine have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are growth/size/body region and homeostasis/metabolism

Disease Ontology : 12 An acute lymphocytic leukemia occuring during childhood.

Related Diseases for Acute Lymphoblastic Leukemia, Childhood

Diseases related to Acute Lymphoblastic Leukemia, Childhood via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
id Related Disease Score Top Affiliating Genes
1 b-cell childhood acute lymphoblastic leukemia 12.4
2 t-cell childhood acute lymphocytic leukemia 12.1
3 cono-spondylar dysplasia 10.3 MTHFR SLC19A1
4 plasmodium vivax malaria 10.3 MME RUNX1
5 hereditary acrokeratotic poikiloderma, weary type 10.3 MTHFD1 MTHFR
6 posterior myocardial infarction 10.3 CDKN2A MME
7 myelocystocele 10.2 MTHFD1 MTHFR
8 posterior meningocele 10.2 MTHFD1 MTHFR
9 pericardial and diaphragmatic defect 10.2 MTHFD1 MTHFR
10 hereditary thrombocytopenia with normal platelets 10.2 MTHFD1 MTHFR
11 thoracolumbosacral spina bifida aperta 10.2 MTHFD1 MTHFR
12 lumbosacral spina bifida aperta 10.2 MTHFD1 MTHFR
13 comt-related pain sensitivity alteration 10.2 ETV6 RUNX1
14 cervical spina bifida aperta 10.2 MTHFD1 MTHFR
15 mycophenolate mofetil embryopathy 10.2 MTHFD1 MTHFR
16 complication in hemodialysis 10.2 MTHFD1 MTHFR
17 intermediate maple syrup urine disease 10.2 MTHFD1 MTHFR
18 intracranial cysts 10.2 MTHFR TYMS
19 46,xx disorder of sex development-anorectal anomalies syndrome 10.2 MTHFD1 MTHFR
20 glycogen storage disease due to liver phosphorylase kinase deficiency 10.2 MTHFD1 MTHFR
21 childhood testicular mixed germ cell tumor 10.1 CDKN2A NQO1
22 subareolar duct papillomatosis 10.1 CDKN2A MME
23 unilateral hemispheric polymicrogyria 10.1 FLT3 RUNX1
24 alcohol abuse 10.1 CDKN2B MME TYMS
25 montefiore syndrome 10.1 ETV6 FLT3
26 deafness, autosomal recessive 45 10.1 MTHFD1 MTHFR
27 oro-mandibular-limb hypogenesis syndrome 10.1 CDKN2A GSTM1 XRCC1
28 adducted thumbs dundar type 10.0 ETV6 FLT3 RUNX1
29 colorectal adenoma 10.0 ETV6 FLT3 RUNX1
30 leukemia 10.0
31 lymphoblastic leukemia 10.0
32 actinobacillosis 10.0 ETV6 FLT3 RUNX1
33 non-distal monosomy 10q 10.0 CDKN2A ETV6 MTHFR XRCC1
34 mixed astrocytoma-ependymoma-oligodendroglioma 10.0 ETV6 MTHFR NQO1 RUNX1
35 testicular fibroma 10.0 ABCB1 CDKN2A
36 hmg-coa synthase-2 deficiency 10.0 MTHFD1 MTHFR SLC19A1 TYMS
37 hepatic flexure cancer 9.9 CDKN2A GSTM1 XRCC1
38 peroxisome biogenesis disorder 7a 9.9 ABCB1 ETV6 FLT3 RUNX1
39 milker's nodule 9.9 ABCB1 ETV6 FLT3 RUNX1
40 pharc syndrome 9.8 ABCB1 MTHFR TYMS XRCC1
41 monoclonal paraproteinemia 9.8 ABCB1 NQO1 TYMS
42 hemophagocytic lymphohistiocytosis 9.8 ABCB1 CDKN2B ETV6 FLT3 RUNX1
43 hyperphosphatasia with mental retardation syndrome 2 9.7 CDKN2A CDKN2B ETV6 FLT3 MME RUNX1
44 amblyopia 9.7 CDKN2A ETV6 FLT3 MME MTHFR RUNX1
45 liver disease 9.7 CDKN2A ETV6 FLT3 MME MTHFR RUNX1
46 acute lymphocytic leukemia 9.6 ABCB1 ETV6 FLT3 GSTM1 MTHFR RUNX1
47 leukemia, acute myeloid 9.5 CDKN2B ETV6 FLT3 GSTM1 NQO1 RUNX1
48 cranioectodermal dysplasia 1 9.5 ABCB1 CDKN2A CDKN2B ETV6 FLT3 MME
49 phosphoserine phosphatase deficiency 9.3 ABCB1 ASNS CDKN2A CDKN2B ETV6 FLT3
50 adult acute lymphocytic leukemia 8.9 ABCB1 ASNS CDKN2A CDKN2B ETV6 GSTM1

Graphical network of the top 20 diseases related to Acute Lymphoblastic Leukemia, Childhood:



Diseases related to Acute Lymphoblastic Leukemia, Childhood

Symptoms & Phenotypes for Acute Lymphoblastic Leukemia, Childhood

MGI Mouse Phenotypes related to Acute Lymphoblastic Leukemia, Childhood:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.27 ABCB1 ASNS CDKN2A ETV6 FLT3 MTHFD1
2 homeostasis/metabolism MP:0005376 10.25 ABCB1 CDKN2A CDKN2B ETV6 FLT3 MME
3 hematopoietic system MP:0005397 10.21 RUNX1 SLC19A1 TPMT ABCB1 ASNS CDKN2A
4 immune system MP:0005387 10.11 ABCB1 CDKN2A CDKN2B ETV6 FLT3 MME
5 endocrine/exocrine gland MP:0005379 10.08 ABCB1 CDKN2A CDKN2B ETV6 FLT3 NR3C1
6 integument MP:0010771 9.97 CDKN2A CDKN2B ETV6 MME MTHFR NQO1
7 mortality/aging MP:0010768 9.93 ABCB1 CDKN2A CDKN2B ETV6 FLT3 MTHFD1
8 liver/biliary system MP:0005370 9.8 RUNX1 SLC19A1 ABCB1 CDKN2A MME NQO1
9 neoplasm MP:0002006 9.5 CDKN2A CDKN2B ETV6 FLT3 NQO1 RUNX1
10 no phenotypic analysis MP:0003012 9.23 ETV6 FLT3 MTHFR NR3C1 RUNX1 ABCB1

Drugs & Therapeutics for Acute Lymphoblastic Leukemia, Childhood

Drugs for Acute Lymphoblastic Leukemia, Childhood (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 382)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Asparaginase Approved Phase 4,Phase 3,Phase 2,Phase 1 9015-68-3
2
Cytarabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 147-94-4 6253
3
Daunorubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 20830-81-3 30323
4
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
5
Idarubicin Approved Phase 4,Phase 3,Phase 2 58957-92-9 42890
6
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
7
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978
8
Pegaspargase Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 130167-69-0
9
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
10
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23214-92-8 31703
11
Lenograstim Approved Phase 4,Phase 3,Phase 2,Phase 1 135968-09-1
12
Thiotepa Approved Phase 4,Phase 3,Phase 2,Phase 1 52-24-4 5453
13
Fludarabine Approved Phase 4,Phase 3,Phase 2,Phase 1 21679-14-1, 75607-67-9 30751
14
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
15
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
16
Thioguanine Approved Phase 4,Phase 3,Phase 2,Phase 1 154-42-7 2723601
17
Oprelvekin Approved, Investigational Phase 4 145941-26-0
18
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
19
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
20
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
21
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
22
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 59-30-3 6037
23
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 58-05-9 54575, 6560146 143
24
Doxil Approved June 1999 Phase 4,Phase 3,Phase 2,Phase 1 31703
25 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
26 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1
27 BB 1101 Phase 4,Phase 3,Phase 2,Phase 1
28 Dexamethasone 21-phosphate Phase 4,Phase 3,Phase 2,Phase 1
29 Dexamethasone acetate Phase 4,Phase 3,Phase 2,Phase 1 1177-87-3
30 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
31 Antibodies Phase 4,Phase 3,Phase 1,Phase 2
32
Ethylene Phase 4 74-85-1 6325
33 Immunoglobulins Phase 4,Phase 3,Phase 1,Phase 2
34 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
35 Hormones Phase 4,Phase 3,Phase 2,Phase 1
36 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
37 Imatinib Mesylate Phase 4,Phase 3,Phase 1,Phase 2 123596
38 Antiemetics Phase 4,Phase 3,Phase 2,Phase 1
39 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
40 Antimitotic Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1
42 Antineoplastic Agents, Phytogenic Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
43 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
44 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
45 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
46 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
47 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
48
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
49 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
50 Antilymphocyte Serum Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 533)
id Name Status NCT ID Phase
1 Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia Unknown status NCT01990807 Phase 4
2 Poly(Ethylene Glycol)(PEG)-Asparaginase During Two Treatment Courses Unknown status NCT00192673 Phase 4
3 Medical Research Council (MRC) Working Party on Leukaemia in Children UK National Acute Lymphoblastic Leukaemia (ALL) Trial: UKALL 2003 Unknown status NCT00222612 Phase 4
4 Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission Unknown status NCT01901666 Phase 4
5 Effect of rhIL-11 in Patients With Thrombocytopenia for Childhood ALL Completed NCT02314273 Phase 4
6 Pulses of Vincristine and Dexamethasone in BFM Protocols for Children With Acute Lymphoblastic Leukemia Completed NCT00411541 Phase 4
7 Learning Impairments Among Survivors of Childhood Cancer Completed NCT00576472 Phase 4
8 Bone Marrow Transplantation in Treating Patients With Hematologic Cancer Completed NCT00003398 Phase 4
9 The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia Recruiting NCT00846703 Phase 4
10 Study on Two Different Formulations of 6-mercaptopurine. Tablet Versus Oral Liquid Recruiting NCT01906671 Phase 4
11 Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study Recruiting NCT02894645 Phase 4
12 Identification of New Immune Factors Specific of Relapse in Childhood B Lineage Acute Lymphoblastic Leukemia Recruiting NCT02618109 Phase 4
13 Intranasal Ketamine for Anxiolysis in Pediatric Emergency Department Patients Recruiting NCT03043430 Phase 4
14 A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT Not yet recruiting NCT03176849 Phase 4
15 Two Combination Chemotherapy Regimens in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia Unknown status NCT00707083 Phase 3
16 Hormone Therapy Plus Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia Unknown status NCT00003437 Phase 3
17 Risk-Adjusted Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia Unknown status NCT00764907 Phase 3
18 Combination Chemotherapy in Treating Children With Relapsed Acute Lymphocytic Leukemia Unknown status NCT00002499 Phase 2, Phase 3
19 Allogeneic Stem Cell Transplantation in Children and Adolescents With Acute Lymphoblastic Leukaemia Unknown status NCT01423747 Phase 3
20 ALL-SCT BFM International- HSCT in Children and Adolescents With ALL Unknown status NCT01423500 Phase 3
21 Treatment of Acute Lymphoblastic Leukemia in Children Unknown status NCT00400946 Phase 3
22 Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma Unknown status NCT00003728 Phase 3
23 Combination Chemotherapy With or Without Idarubicin and Peripheral Stem Cell Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome Unknown status NCT00002989 Phase 3
24 Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia Completed NCT00002816 Phase 3
25 ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia Intermittent Versus Continuous PEG Asparaginase Completed NCT00819351 Phase 3
26 Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia Completed NCT00005585 Phase 3
27 ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia (ALL) - 6MP Consolidation Therapy Completed NCT00816049 Phase 3
28 Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia Completed NCT00613457 Phase 3
29 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia Completed NCT00022737 Phase 3
30 A Severity-Adapted Clinical Trial of Diminished Bone Mineral Density in Acute Lymphoblastic Leukemia Survivors Completed NCT00186901 Phase 3
31 Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia Completed NCT00005945 Phase 3
32 Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia Completed NCT00015873 Phase 3
33 Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia Completed NCT00005596 Phase 3
34 Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia Completed NCT00381680 Phase 3
35 Combination Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia Completed NCT00967057 Phase 3
36 Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia Completed NCT00005603 Phase 3
37 Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia Completed NCT00002744 Phase 3
38 Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia Completed NCT00002812 Phase 3
39 Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia Completed NCT00430118 Phase 3
40 Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Completed NCT00720109 Phase 2, Phase 3
41 Dexamethasone Compared With Prednisone During Induction Therapy and MTX With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Completed NCT00075725 Phase 3
42 Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma Completed NCT01230983 Phase 3
43 Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant Completed NCT01305200 Phase 3
44 Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia Completed NCT00005977 Phase 3
45 Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma Completed NCT00003187 Phase 2, Phase 3
46 Bone Marrow Transplantation in Treating Patients With Acute Leukemia in First or Second Remission Completed NCT00002534 Phase 3
47 Treatment of Bone Marrow to Prevent Graft-Versus-Host Disease in Patients With Acute or Chronic Leukemia Undergoing Bone Marrow Transplantation Completed NCT00004255 Phase 2, Phase 3
48 TITLE:Less Intensive Therapy for Children With Non-Hodgkin's Lymphoma Completed NCT00002757 Phase 3
49 Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial Completed NCT00750009 Phase 3
50 Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation Completed NCT00045292 Phase 3

Search NIH Clinical Center for Acute Lymphoblastic Leukemia, Childhood

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Stem-cell-based therapeutic approaches for Acute Lymphoblastic Leukemia, Childhood:
Hematopoietic stem cells for treatment of hematologic malignancies
Embryonic/Adult Cultured Cells Related to Acute Lymphoblastic Leukemia, Childhood:
Bone marrow-derived hematopoietic stem cells

Genetic Tests for Acute Lymphoblastic Leukemia, Childhood

Anatomical Context for Acute Lymphoblastic Leukemia, Childhood

MalaCards organs/tissues related to Acute Lymphoblastic Leukemia, Childhood:

39
Bone, Bone Marrow

Publications for Acute Lymphoblastic Leukemia, Childhood

Variations for Acute Lymphoblastic Leukemia, Childhood

Copy number variations for Acute Lymphoblastic Leukemia, Childhood from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 250737 9 21967751 21994490 Deletion CDKN2A pediatric acute lymphoblastic leukemia

Expression for Acute Lymphoblastic Leukemia, Childhood

Search GEO for disease gene expression data for Acute Lymphoblastic Leukemia, Childhood.

Pathways for Acute Lymphoblastic Leukemia, Childhood

GO Terms for Acute Lymphoblastic Leukemia, Childhood

Cellular components related to Acute Lymphoblastic Leukemia, Childhood according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.44 ASNS CDKN2A CDKN2B ETV6 FLT3 GSTM1

Biological processes related to Acute Lymphoblastic Leukemia, Childhood according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.76 ABCB1 MTHFR TYMS XRCC1
2 response to toxic substance GO:0009636 9.61 ASNS NQO1 TYMS
3 negative regulation of phosphorylation GO:0042326 9.48 CDKN2A CDKN2B
4 hematopoietic stem cell proliferation GO:0071425 9.4 ETV6 RUNX1
5 replicative senescence GO:0090399 9.37 CDKN2A MME
6 tetrahydrofolate metabolic process GO:0046653 9.32 MTHFR TYMS
7 response to folic acid GO:0051593 9.26 MTHFR TYMS
8 methionine metabolic process GO:0006555 9.16 MTHFD1 MTHFR
9 folic acid metabolic process GO:0046655 9.13 MTHFD1 MTHFR SLC19A1
10 tetrahydrofolate interconversion GO:0035999 8.8 MTHFD1 MTHFR TYMS

Molecular functions related to Acute Lymphoblastic Leukemia, Childhood according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cofactor binding GO:0048037 9.16 ASNS TYMS
2 folic acid binding GO:0005542 8.96 SLC19A1 TYMS
3 cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861 8.62 CDKN2A CDKN2B

Sources for Acute Lymphoblastic Leukemia, Childhood

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....