MCID: ACT059
MIFTS: 36

Acute Maxillary Sinusitis

Categories: Respiratory diseases

Aliases & Classifications for Acute Maxillary Sinusitis

MalaCards integrated aliases for Acute Maxillary Sinusitis:

Name: Acute Maxillary Sinusitis 12 14 69
Acute Antritis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2050
ICD10 33 J01.0 J01.00
ICD9CM 35 461.0
UMLS 69 C0155804

Summaries for Acute Maxillary Sinusitis

Disease Ontology : 12 A maxillary sinusitis which lasts for less than 4 weeks.

MalaCards based summary : Acute Maxillary Sinusitis, also known as acute antritis, is related to sinusitis and maxillary sinusitis. An important gene associated with Acute Maxillary Sinusitis is MAT2A (Methionine Adenosyltransferase 2A), and among its related pathways/superpathways are Primary immunodeficiency and Warfarin Pathway, Pharmacodynamics. The drugs Biaxin XL and Azithromycin have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and tonsil, and related phenotypes are cardiovascular system and immune system

Related Diseases for Acute Maxillary Sinusitis

Diseases in the Maxillary Sinusitis family:

Chronic Maxillary Sinusitis Acute Maxillary Sinusitis

Diseases related to Acute Maxillary Sinusitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 186)
id Related Disease Score Top Affiliating Genes
1 sinusitis 10.8
2 maxillary sinusitis 10.8
3 cystoisosporiasis 10.7 CRP HCCS
4 acquired hemophilia 10.5 C3 CRP
5 acquired polycythemia 10.5 CD40LG CRP
6 cannabis dependence 10.5 CD40LG CRP
7 hypertensive heart disease 10.5 CD40LG CRP
8 rocky mountain spotted fever 10.5 CD40LG CRP
9 beach ear 10.5 CD40LG CRP
10 central nervous system leiomyosarcoma 10.5 CD40LG CRP
11 arcus senilis 10.5 C3 CRP
12 female breast upper-inner quadrant cancer 10.4 CRP F9
13 functional gastric disease 10.4 CD40LG CRP
14 secretory diarrhea 10.4 CD40LG GAS6
15 megaloblastic anemia 10.4 CD40LG CRP
16 hypolipoproteinemia 10.4 CD40LG CRP
17 compensatory emphysema 10.4 CD40LG CRP
18 plummer's disease 10.3 CD40LG CRP
19 diphtheritic cystitis 10.2 CD79A CRP
20 focal embolic glomerulonephritis 10.2 CD79A CRP
21 atrophy of prostate 10.2 CD40LG CRP
22 brain glioblastoma multiforme 10.2 CRP PPIG
23 pediatric supratentorial ependymoma 10.2 CD40LG CRP
24 tarp syndrome 10.1 CD79A HCCS
25 intracranial primitive neuroectodermal tumor 10.1 CD79A GAS6
26 ocular hyperemia 10.1 CD40LG F9
27 alcoholic neuropathy 10.1 CD40LG CD79A
28 calloso-genital dysplasia 10.1 CD40LG CD79A
29 variola major 10.1 CD40LG CD79A
30 mu chain disease 10.1 CD40LG CD79A
31 rabies 10.1 CD40LG CD79A
32 familial retinoblastoma 10.1 CD40LG CD79A
33 anti-basement membrane glomerulonephritis 10.1 CD40LG CD79A
34 microinvasive cervical squamous cell carcinoma 10.1 CD40LG CD79A
35 fetal erythroblastosis 10.1 CD40LG CD79A
36 spinal canal and spinal cord meningioma 10.1 CD40LG CD79A
37 trichostrongyloidiasis 10.1 CD40LG CD79A
38 leukodystrophy 10.1 CD40LG CD79A
39 retinal microaneurysm 10.1 CD40LG CD79A
40 heart septal defect 10.1 CD40LG CD79A
41 cryptorchidism arachnodactyly mental retardation 10.1 CD40LG CD79A
42 acute kidney tubular necrosis 10.1 CD40LG CD79A
43 secretory meningioma 10.1 CD40LG CD79A
44 hodgkin's lymphoma, nodular sclerosis 10.1 CD40LG CD79A
45 imperforate oropharynx-costo vetebral anomalies 10.1 CD40LG CD79A
46 malignant otitis externa 10.1 CD40LG CD79A
47 transient hypogammaglobulinemia 10.1 CD40LG CD79A
48 benign epilepsy with centrotemporal spikes 10.1 CD40LG CD79A
49 tongue cancer 10.1 CD40LG CD79A
50 hydrops of gallbladder 10.1 CD40LG CD79A

Comorbidity relations with Acute Maxillary Sinusitis via Phenotypic Disease Network (PDN): (show all 11)


Acute Cystitis Acute Ethmoiditis
Acute Frontal Sinusitis Acute Sphenoidal Sinusitis
Bronchitis Chronic Ethmoiditis
Chronic Maxillary Sinusitis Deficiency Anemia
Esophagitis Heart Disease
Hypertension, Essential

Graphical network of the top 20 diseases related to Acute Maxillary Sinusitis:



Diseases related to Acute Maxillary Sinusitis

Symptoms & Phenotypes for Acute Maxillary Sinusitis

MGI Mouse Phenotypes related to Acute Maxillary Sinusitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.43 C3 CD40LG CRP F9 GAS6 HCCS
2 immune system MP:0005387 9.17 C3 CD40LG CD79A CRP F9 GAS6

Drugs & Therapeutics for Acute Maxillary Sinusitis

FDA approved drugs:

id Drug Name Active Ingredient(s) 17 Company Approval Date
1
Biaxin XL 17 CLARITHROMYCIN Abbott Laboratories March 2000

Drugs for Acute Maxillary Sinusitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 49)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 53477736 447043
2
Clarithromycin Approved Phase 4 81103-11-9 84029
3
Erythromycin Approved, Vet_approved Phase 4 114-07-8 12560
4
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
5
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
6
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
7
Norgestimate Approved Phase 4 35189-28-7 6540478
8
Telithromycin Approved Phase 4 191114-48-4 5462516
9 Anti-Bacterial Agents Phase 4,Phase 3
10 Antibiotics, Antitubercular Phase 4
11 Anti-Infective Agents Phase 4,Phase 3
12 Antitubercular Agents Phase 4
13 Cytochrome P-450 CYP3A Inhibitors Phase 4
14 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
15 Erythromycin Estolate Phase 4
16 Erythromycin Ethylsuccinate Phase 4
17 Erythromycin stearate Phase 4
18 Contraceptive Agents Phase 4
19 Contraceptives, Oral Phase 4
20 Contraceptives, Oral, Combined Phase 4
21 Estradiol 17 beta-cypionate Phase 4
22 Estradiol 3-benzoate Phase 4
23 Estradiol valerate Phase 4 979-32-8
24 Fluoroquinolones Phase 4
25 Norgestimate, ethinyl estradiol drug combination Phase 4
26 Nucleic Acid Synthesis Inhibitors Phase 4
27 Polyestradiol phosphate Phase 4
28 Topoisomerase Inhibitors Phase 4,Phase 3
29
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
30
Ofloxacin Approved Phase 3 82419-36-1 4583
31
Amoxicillin Approved, Vet_approved Phase 3 26787-78-0 33613 2171
32 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
33 Renal Agents Phase 3
34 Amoxicillin-Potassium Clavulanate Combination Phase 3
35 beta-Lactamase Inhibitors Phase 3
36 Clavulanic Acid Phase 3
37
Ephedrine Approved 299-42-3 9294
38
Pseudoephedrine Approved 90-82-4 7028
39
Xylometazoline Approved 526-36-3 5709
40 Adrenergic Agents
41 Anti-Asthmatic Agents
42 Autonomic Agents
43 Bronchodilator Agents
44 Central Nervous System Stimulants
45 Nasal Decongestants
46 Neurotransmitter Agents
47 Peripheral Nervous System Agents
48 Respiratory System Agents
49 Vasoconstrictor Agents

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Aizthromycin or Clarithromycin in H-pylori Eradication Regimen Completed NCT01667692 Phase 4 azithromycin;clarithmycin
2 Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox Completed NCT00668304 Phase 4 Avelox (Moxifloxacin, BAY12-8039)
3 Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis Terminated NCT00245440 Phase 4 Azithromycin;Telithromycin
4 A Study Evaluating the Safety and Efficacy of Treating Sinus Infection With Levofloxacin 750 mg for 5 Days. Completed NCT00236652 Phase 3 levofloxacin
5 A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Sinus Infections in Adults Completed NCT00643409 Phase 3 azithromycin SR (Zithromax; compound: CP-62,993);levofloxacin
6 A Study of the Safety and Effectiveness of Levofloxacin Compared With Amoxicillin/Clavulanate Potassium in the Treatment of Adults With Rapid Onset of Severe Inflammation/Infection of the Sinuses Completed NCT00249210 Phase 3 levofloxacin
7 Acute Upper Respiratory Tract Infection - When is Bacteria Involved? Unknown status NCT01580137
8 Non-Interventional Open Label Prospective Comparative Observational Study Of Evaluation Of Compliance In The Empiric Treatment With Azithromycin SR Versus Amoxiclav 1000 Mg In Adult Patients With Of Acute Bacterial Maxillary Sinusitis Completed NCT01032174 Azithromycin SR;Amoxiclav 1000 mg
9 Levofloxacin in Bacterial Rhinosinussitis Completed NCT02712502 Levofloxacin;Amoxicillin-Potassium Clavulanate Combination

Search NIH Clinical Center for Acute Maxillary Sinusitis

Genetic Tests for Acute Maxillary Sinusitis

Anatomical Context for Acute Maxillary Sinusitis

MalaCards organs/tissues related to Acute Maxillary Sinusitis:

39
Testes, Skin, Tonsil, Bone

Publications for Acute Maxillary Sinusitis

Articles related to Acute Maxillary Sinusitis:

(show top 50) (show all 130)
id Title Authors Year
1
Management of acute maxillary sinusitis after sinus bone grafting procedures with simultaneous dental implants placement - a retrospective study. ( 27169511 )
2016
2
Root Cause Analysis: An Examination of Odontogenic Origins of Acute Maxillary Sinusitis in Both Immunocompetent & Immunocompromised Patients. ( 27798445 )
2016
3
WITHDRAWN: Antibiotics for acute maxillary sinusitis in adults. ( 26471061 )
2015
4
Antibiotics for acute maxillary sinusitis in adults. ( 24515610 )
2014
5
Cluster headache associated with acute maxillary sinusitis. ( 24133652 )
2013
6
Cluster headache and acute maxillary sinusitis. ( 23381843 )
2013
7
Radiology quiz case 1. Acute maxillary sinusitis secondary to a migrated dental implant obstructing the ostiomeatal complex. ( 21844418 )
2011
8
Presentation and treatment of acute maxillary sinusitis in general practice: a French observational study. ( 21468380 )
2011
9
The association between paranasal computerized tomography scans and symptoms and signs in a general practice population with acute maxillary sinusitis. ( 21143525 )
2011
10
Acute maxillary sinusitis detected by bedside emergency department ultrasonography. ( 21373341 )
2010
11
Antibiotics for acute maxillary sinusitis. ( 20141093 )
2009
12
Economic evaluation of Sinfrontal in the treatment of acute maxillary sinusitis in adults. ( 19799472 )
2009
13
Frequency of a dental source for acute maxillary sinusitis. ( 19160401 )
2009
14
Symptoms and signs in culture-proven acute maxillary sinusitis in a general practice population. ( 19775340 )
2009
15
Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis. ( 18313879 )
2008
16
Antibiotics for acute maxillary sinusitis. ( 18425861 )
2008
17
Extracts from The Cochrane Library: Antibiotics for acute maxillary sinusitis. ( 18922332 )
2008
18
Acute maxillary sinusitis associated with internal sinus lifting: report of a case. ( 19212512 )
2008
19
Frequency of recovery of pathogens from the nasopharynx of children with acute maxillary sinusitis before and after the introduction of vaccination with the 7-valent pneumococcal vaccine. ( 17267051 )
2007
20
Serial sinus aspirate samples during high-dose, short-course levofloxacin treatment of acute maxillary sinusitis. ( 17178300 )
2007
21
Recommended and prescribed symptomatic treatment for acute maxillary sinusitis in Finnish primary care. ( 17956017 )
2007
22
Efficacy of a complex homeopathic medication (Sinfrontal) in patients with acute maxillary sinusitis: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial. ( 17362845 )
2007
23
Antibiotics and topical nasal steroid for treatment of acute maxillary sinusitis: a randomized controlled trial. ( 18056902 )
2007
24
Implementing guidelines on acute maxillary sinusitis in general practice--a randomized controlled trial. ( 17237494 )
2007
25
Macrolide immunomodulatory effects and symptom resolution in acute exacerbation of chronic bronchitis and acute maxillary sinusitis: a focus on clarithromycin. ( 16771618 )
2006
26
Effect of telithromycin and azithromycin on nasopharyngeal bacterial flora in patients with acute maxillary sinusitis. ( 16618915 )
2006
27
Frequency of recovery of pathogens causing acute maxillary sinusitis in adults before and after introduction of vaccination of children with the 7-valent pneumococcal vaccine. ( 16772423 )
2006
28
Eradication of pathogens from the nasopharynx after therapy of acute maxillary sinusitis with low- or high-dose amoxicillin/clavulanic acid. ( 16226017 )
2005
29
Clinical and bacteriological efficacy of 5-day telithromycin in acute maxillary sinusitis: a pooled analysis. ( 15780415 )
2005
30
Current position of the management of community-acquired acute maxillary sinusitis or rhinosinusitis in France and literature review. ( 16405280 )
2005
31
Bacteriological efficacy of 5-day therapy with telithromycin in acute maxillary sinusitis. ( 15737519 )
2005
32
Recovery of interfering bacteria in the nasopharynx following antimicrobial therapy of acute maxillary sinusitis with telithromycin or amoxicillin-clavulanate. ( 16251334 )
2005
33
Patients' and physicians' views on the management of acute maxillary sinusitis. ( 15119516 )
2004
34
Antimicrobial resistance in the nasopharyngeal flora of children with acute maxillary sinusitis and maxillary sinusitis recurring after amoxicillin therapy. ( 14729759 )
2004
35
Use of pharmacodynamic end points in the evaluation of gatifloxacin for the treatment of acute maxillary sinusitis. ( 15156435 )
2004
36
Management of acute maxillary sinusitis in Finnish primary care. Results from the nationwide MIKSTRA study. ( 15255494 )
2004
37
Antibiotics for acute maxillary sinusitis. ( 12804392 )
2003
38
Efficacy and tolerability of telithromycin for 5 or 10 days vs amoxicillin/clavulanic acid for 10 days in acute maxillary sinusitis. ( 14503094 )
2003
39
Clinical inquiries. Are antibiotics helpful for acute maxillary sinusitis? ( 12791232 )
2003
40
Evidence-based emergency medicine/systematic review abstract: Antibiotic treatment for acute maxillary sinusitis. ( 14581925 )
2003
41
Efficacy and tolerability of once-daily therapy with telithromycin for 5 or 10 days for the treatment of acute maxillary sinusitis. ( 12011543 )
2002
42
The treatment duration of acute maxillary sinusitis: how long should it be? A nasal smear controlled study. ( 12526248 )
2002
43
Diagnostic accuracy of acute maxillary sinusitis in adults in primary care. ( 12086283 )
2002
44
Moxifloxacin versus amoxicillin clavulanate in the treatment of acute maxillary sinusitis: a primary care experience. ( 11452678 )
2001
45
Comparison of ultrasound, radiography, and clinical examination in the diagnosis of acute maxillary sinusitis: a systematic review. ( 11004420 )
2000
46
Antibiotics for acute maxillary sinusitis. ( 10796515 )
2000
47
Which antibiotics lead to higher clinical cure rates in adults with acute maxillary sinusitis? ( 10903293 )
2000
48
Phase III, randomized, double-blind study of clarithromycin extended-release and immediate-release formulations in the treatment of adult patients with acute maxillary sinusitis. ( 11192134 )
2000
49
Validity of ultrasonography in diagnosis of acute maxillary sinusitis. ( 11115287 )
2000
50
Comparison of moxifloxacin and cefuroxime axetil in the treatment of acute maxillary sinusitis. Sinusitis Infection Study Group. ( 10566563 )
1999

Variations for Acute Maxillary Sinusitis

Expression for Acute Maxillary Sinusitis

Search GEO for disease gene expression data for Acute Maxillary Sinusitis.

Pathways for Acute Maxillary Sinusitis

Pathways related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.52 CD40LG CD79A
2 9.8 F9 GAS6

GO Terms for Acute Maxillary Sinusitis

Cellular components related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 8.8 C3 F9 GAS6

Biological processes related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 B cell proliferation GO:0042100 9.16 CD40LG CD79A
2 positive regulation of phagocytosis GO:0050766 8.96 C3 GAS6
3 signal peptide processing GO:0006465 8.62 F9 GAS6

Sources for Acute Maxillary Sinusitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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