MCID: ACT105
MIFTS: 54

Acute Mountain Sickness malady

Rare diseases category

Summaries for Acute Mountain Sickness

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Wikipedia:63 Altitude sickness?also known as acute mountain sickness (AMS), altitude illness, hypobaropathy, \"the... more...

MalaCards based summary: Acute Mountain Sickness, also known as high altitude pulmonary edema, is related to cor pulmonale and obesity. An important gene associated with Acute Mountain Sickness is BDKRB2 (bradykinin receptor B2), and among its related pathways are Effects of nitric oxide and Hypoxic and oxygen homeostasis regulation of HIF-1-alpha. The drugs acetazolamide and acetazolamide sodium and the compounds nebivolol and atenolol have been mentioned in the context of this disorder. Affiliated tissues include endothelial, brain and heart, and related mouse phenotypes are adipose tissue and digestive/alimentary.

Aliases & Classifications for Acute Mountain Sickness

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Sources:
41NIH Rare Diseases, 47Orphanet, 60UMLS, 26ICD10 via Orphanet
See all sources

Acute Mountain Sickness, Aliases & Descriptions:

Name: Acute Mountain Sickness 41 60
High Altitude Pulmonary Edema 41 47 60
High Altitude Cerebral Edema 41 60
Altitude Sickness 41 60
Lead Intoxication 41
 
Mountain Sickness 41
Altitude Anoxia 41
Lead Poisoning 41
Saturnism 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Characteristics (Orphanet epidemiological data):

47
high altitude pulmonary edema:
Prevalence: 1-9/1000000 (Europe)


External Ids:

Orphanet47 330012
ICD10 via Orphanet26 J81

Related Diseases for Acute Mountain Sickness

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Diseases related to Acute Mountain Sickness via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 182)
idRelated DiseaseScoreTop Affiliating Genes
1cor pulmonale30.7EDN1, AGTR1
2obesity30.5HIF1A, FLT1, ADRB2, CCK, NOS3
3polycythemia30.3VHL, HIF1A
4kidney disease30.2NOS3, AGTR1, VEGFA
5pulmonary hypertension30.1HIF1A, EDN1, NOS3, FLT1
6hypoxia11.0
7cerebritis11.0
8blindness10.7
9headache10.7
10endotheliitis10.7
11pulmonary edema10.5
12pericardial effusion10.5PIK3C2A
13coats disease10.5ENO2
14subependymal giant cell astrocytoma10.5ENO2
15ataxia10.5
16acute chest syndrome10.5NOS3
17pre-eclampsia10.4FLT1
18alveolar soft-part sarcoma10.4ENO2, MB
19hepatorenal syndrome10.4EDN1
20oligohydramnios10.4ACE
21granular cell tumor10.4ENO2, MB
22creatine phosphokinase, elevated serum10.4PIK3C2A, MB
23intracranial hypertension10.4
24retinitis10.4
25gas gangrene10.4PIK3C2A, MB
26rhabdomyosarcoma 2, alveolar10.4ENO2, MB
27intermediate coronary syndrome10.4MB, PIK3C2A
28anuria10.4MB, ACE
29spinocerebellar ataxia10.4ENO2, MB
30renal tubular dysgenesis10.4ACE, AGTR1
31renovascular hypertension10.3AGTR1, ACE
32nephrosclerosis10.3ACE, AGTR1
33diabetic macular edema10.3VEGFA
34medullary thyroid carcinoma, familial10.3CCK, VHL, ENO2
35raynaud disease10.3EDN1, AGTR1
36glucagonoma10.3ENO2, CCK
37malignant mixed mullerian tumor10.3MB, ENO2
38hypertensive heart disease10.3AGTR1, ACE
39prinzmetal's variant angina10.3NOS3, EDN1
40systemic lupus erythematosus10.3
41bronchopulmonary dysplasia10.3
42adie syndrome10.3
43patent foramen ovale10.3
44influenza10.3
45lupus erythematosus10.3
46pulmonary edema of mountaineers10.3
47diffuse alveolar hemorrhage10.3
48pulmonary artery hypoplasia10.3
49coronary artery vasospasm10.3EDN1, NOS3
50neuroleptic malignant syndrome10.3MB, PIK3C2A

Graphical network of the top 20 diseases related to Acute Mountain Sickness:



Diseases related to acute mountain sickness

Symptoms for Acute Mountain Sickness

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Drugs & Therapeutics for Acute Mountain Sickness

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Drug clinical trials:

Search ClinicalTrials for Acute Mountain Sickness

Search NIH Clinical Center for Acute Mountain Sickness

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Acute Mountain Sickness

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Anatomical Context for Acute Mountain Sickness

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MalaCards organs/tissues related to Acute Mountain Sickness:

31
Endothelial, Brain, Heart, Lung, Testes, Pituitary, Skeletal muscle, Kidney, Neutrophil

Animal Models for Acute Mountain Sickness or affiliated genes

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MGI Mouse Phenotypes related to Acute Mountain Sickness:

35 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.9PIK3C2A, ADRB2, ACE, NOS3, BDKRB2
2MP:00053818.3EDN1, VEGFA, HIF1A, VHL, NOS3, BDKRB2
3MP:00053708.2VEGFA, HIF1A, ACE, VHL, NOS3
4MP:00053908.2EDN1, VEGFA, HIF1A, ADRB2, VHL, NOS3
5MP:00053808.1EDN1, VEGFA, HIF1A, FLT1, VHL, MB
6MP:00053888.0ENO2, MB, NOS3, HIF1A, VEGFA
7MP:00028738.0EDN1, VEGFA, HIF1A, FLT1, VHL, NOS3
8MP:00053827.8EDN1, VEGFA, HIF1A, VHL, ENO2
9MP:00053697.8EDN1, VEGFA, HIF1A, FLT1, ADRB2, VHL
10MP:00053897.7VEGFA, HSPA1B, HSPA1A, FLT1, ACE, VHL
11MP:00053797.7EDN1, VEGFA, HIF1A, ADRB2, CCK, ACE
12MP:00053867.2VEGFA, HIF1A, FLT1, ADRB2, ACE, NOS3
13MP:00053677.1EDN1, PIK3C2A, VEGFA, HSPA1B, HIF1A, ACE
14MP:00053977.1PIK3C2A, VEGFA, HIF1A, FLT1, ADRB2, ACE
15MP:00053876.8PIK3C2A, VEGFA, HSPA1B, HIF1A, FLT1, ADRB2
16MP:00036316.6EDN1, VEGFA, HSPA1B, HSPA1A, HIF1A, FLT1
17MP:00107686.4HIF1A, HSPA1B, VEGFA, PIK3C2A, EDN1, FLT1
18MP:00053786.3HIF1A, HSPA1A, HSPA1B, VEGFA, PIK3C2A, FLT1
19MP:00053856.2EDN1, VEGFA, HSPA1B, HSPA1A, HIF1A, FLT1
20MP:00053846.0FLT1, HIF1A, HSPA1A, HSPA1B, VEGFA, ADRB2
21MP:00053765.4AGTR1, EDN1, PIK3C2A, VEGFA, HSPA1B, HSPA1A

Publications for Acute Mountain Sickness

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Articles related to Acute Mountain Sickness:

(show top 50)    (show all 503)
idTitleAuthorsYear
1
Rating of perceived exertion and acute mountain sickness during a high-altitude trek. (25479264)
2014
2
The effect of hypoxemia and exercise on acute mountain sickness symptoms. (23154995)
2013
3
Rhodiola crenulata extract for prevention of acute mountain sickness: a randomized, double-blind, placebo-controlled, crossover trial. (24176010)
2013
4
Associations between vascular endothelial growth factor gene polymorphisms and susceptibility to acute mountain sickness. (23321170)
2012
5
Acute mountain sickness without headache at low altitude. (23323193)
2012
6
Acute mountain sickness impact among travelers to Cusco, Peru. (22776382)
2012
7
Changes in cardiac autonomic activity during a passive 8 hour acute exposure to 5a88500 m normobaric hypoxia are not related to the development of acute mountain sickness. (22290324)
2012
8
Spironolactone does not prevent acute mountain sickness: a prospective, double-blind, randomized, placebo-controlled trial by SPACE Trial Group (spironolactone and acetazolamide trial in the prevention of acute mountain sickness group). (21377114)
2011
9
Sea-level assessment of dynamic cerebral autoregulation predicts susceptibility to acute mountain sickness at high altitude. (21960569)
2011
10
The prevalence of and risk factors for acute mountain sickness in the Eastern and Western Alps. (21190503)
2010
11
Impaired cerebral autoregulation in acute mountain sickness: incidental yet adaptive? (20814008)
2010
12
Acute mountain sickness: pathophysiology, prevention, and treatment. (20417340)
2010
13
Alternations of heart rate variability at lower altitude in the predication of trekkers with acute mountain sickness at high altitude. (20051736)
2010
14
Genotype at the missense G894T polymorphism (Glu298Asp) in the NOS3 gene is associated with susceptibility to acute mountain sickness. (19775216)
2009
15
Prevalence of acute mountain sickness among Finnish trekkers on Mount Kilimanjaro, Tanzania: an observational study. (19115914)
2008
16
Prevention of acute mountain sickness in Nepali porters: a controlled trial. (17447720)
2007
17
Acute mountain sickness with reversible vasospasm. (17617424)
2007
18
Acute mountain sickness: medical problems associated with acute and subacute exposure to hypobaric hypoxia. (17099095)
2006
19
Variables contributing to acute mountain sickness on the summit of Mt Whitney. (17219785)
2006
20
Acetazolamide 125 mg BD is not significantly different from 375 mg BD in the prevention of acute mountain sickness: the prophylactic acetazolamide dosage comparison for efficacy (PACE) trial. (16544963)
2006
21
New epilepsy seizure at high altitude without signs of acute mountain sickness or high altitude cerebral edema. (16544970)
2006
22
Effect of magnesium, high altitude and acute mountain sickness on blood flow velocity in the middle cerebral artery. (14572304)
2004
23
Pathophysiology of acute mountain sickness (AMS). (15136783)
2004
24
Hypoxic ventilatory response, ventilation, gas exchange, and fluid balance in acute mountain sickness. (12631422)
2002
25
Does theophylline really improve acute mountain sickness? (11405540)
2001
26
Arterial oxygen saturation for prediction of acute mountain sickness. (9856544)
1998
27
Gammow bag for acute mountain sickness. (9635981)
1998
28
Seizure and hemiparesis at high-altitude outside the setting of acute mountain sickness. (11990167)
1997
29
The illness of ascent: acute mountain sickness. (9429378)
1997
30
How can acute mountain sickness be quantified at moderate altitude? (8683517)
1996
31
Simulated descent v dexamethasone in treatment of acute mountain sickness: a randomised trial. (7767194)
1995
32
Effects of acetazolamide on overnight oxygenation and acute mountain sickness in patients with asthma. (8491304)
1993
33
Acute mountain sickness in children at 2835 meters. (8427234)
1993
34
Pressurization and acute mountain sickness. (8240197)
1993
35
Acetazolamide in the treatment of acute mountain sickness: clinical efficacy and effect on gas exchange. (1739236)
1992
36
Acute mountain sickness susceptibility, fitness and hypoxic ventilatory response. (1783072)
1991
37
Cognitive changes at high altitude in healthy climbers and in climbers developing acute mountain sickness. (2031628)
1991
38
Severe acute mountain sickness. (2133049)
1990
39
Incidence of acute mountain sickness at intermediate altitudes. (2724500)
1989
40
Acute mountain sickness and acetazolamide. (3399193)
1988
41
Effect of carbon dioxide in acute mountain sickness: a rediscovery. (2901515)
1988
42
Effect of dexamethasone on symptoms of acute mountain sickness at Pikes Peak, Colorado (4,300 m). (3619842)
1987
43
Effect of spironolactone on acute mountain sickness. (3718378)
1986
44
Acute mountain sickness, antacids, and ventilation during rapid, active ascent of Mount Rainier. (6347173)
1983
45
Acetazolamide for acute mountain sickness. (6653952)
1983
46
Plasma volume, body weight, and acute mountain sickness. (6131227)
1983
47
Acute mountain sickness and the edemas of high altitude: a common pathogenesis? (7323495)
1981
48
Acute mountain sickness. (64667)
1977
49
Acute mountain sickness. (5782719)
1969
50
Effect of acetazolamide on acute mountain sickness. (4877992)
1968

Variations for Acute Mountain Sickness

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Expression for genes affiliated with Acute Mountain Sickness

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Search GEO for disease gene expression data for Acute Mountain Sickness.

Pathways for genes affiliated with Acute Mountain Sickness

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Pathways related to Acute Mountain Sickness according to GeneCards Suite gene sharing:

(show all 29)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Quercetin and Nf-kB/ AP-1 induced cell apoptosis36
9.9MB, NOS3
29.8VHL, HIF1A
39.4FLT1, VEGFA
4
Show member pathways
9.4FLT1, VEGFA
59.4HSPA1B, HSPA1A, BDKRB2
69.4ADRB2, NOS3, BDKRB2, AGTR1
7
Show member pathways
9.4AGTR1, BDKRB2, CCK, EDN1
8
Show member pathways
9.3NOS3, HSPA1A, HSPA1B
9
Show member pathways
9.3AGTR1, BDKRB2, NOS3, ACE
10
Show member pathways
9.2NOS3, FLT1, PIK3C2A
11
Show member pathways
9.2NOS3, FLT1, PIK3C2A
129.2VHL, FLT1, VEGFA
13
Show member pathways
9.1VHL, HIF1A, VEGFA
149.1VHL, HIF1A, VEGFA
15
Show member pathways
9.1EDN1, ADRB2, CCK, BDKRB2, AGTR1
169.0NOS3, VHL, FLT1, HIF1A
17
Show member pathways
9.0EDN1, VEGFA, HIF1A
189.0EDN1, VEGFA, HIF1A
19
Show member pathways
9.0HIF1A, FLT1, ACE, AGTR1
209.0HSPA1B, HSPA1A, FLT1, ADRB2
21
Show member pathways
8.9VEGFA, FLT1, CCK, NOS3
22
Show member pathways
Angiogenesis36
8.7NOS3, FLT1, HIF1A, VEGFA
23
Show member pathways
8.6PIK3C2A, VEGFA, FLT1, NOS3
24
Show member pathways
VEGFR1 specific signals36
8.4VEGFA, HIF1A, FLT1, VHL, NOS3
258.2EDN1, HSPA1B, HSPA1A, HIF1A, VHL, NOS3
26
Show member pathways
Cytoskeleton remodeling FAK signaling58
Development Endothelin 1 EDNRA transactivation of EGFR58
8.1EDN1, VEGFA, HSPA1B, HSPA1A, NOS3, BDKRB2
27
Show member pathways
7.9EDN1, VEGFA, HSPA1B, HSPA1A, FLT1, NOS3
28
Show member pathways
7.6EDN1, VEGFA, HIF1A, FLT1, ADRB2, CCK
297.2ENO2, EDN1, VEGFA, HIF1A, FLT1, VHL

Compounds for genes affiliated with Acute Mountain Sickness

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Compounds related to Acute Mountain Sickness according to GeneCards Suite gene sharing:

(show top 50)    (show all 215)
idCompoundScoreTop Affiliating Genes
1nebivolol43 1210.6ACE, ADRB2, EDN1, NOS3
2atenolol43 49 28 24 1213.5AGTR1, ACE, ADRB2, EDN1
3lacidipine439.5EDN1, ACE, AGTR1
4diltiazem43 28 49 1212.5AGTR1, CCK, EDN1, ACE
5enalapril43 49 1211.4EDN1, ACE, ADRB2, AGTR1
6lisinopril43 49 24 1212.4VEGFA, BDKRB2, AGTR1, ACE
7captopril43 59 49 28 1213.3BDKRB2, ACE, EDN1, AGTR1
8perindopril43 49 1211.2VEGFA, NOS3, ACE, AGTR1
9fluvastatin43 49 28 1212.1AGTR1, MB, ACE, NOS3, PIK3C2A
108-isoprostane439.1NOS3, HSPA1A, EDN1, AGTR1
11sunitinib43 49 1211.0HIF1A, VHL, VEGFA, FLT1
12l-nmma439.0HIF1A, CCK, NOS3, BDKRB2, AGTR1, EDN1
13sildenafil28 43 49 24 1213.0NOS3, ACE, EDN1, VEGFA
14ang ii438.9AGTR1, EDN1, VEGFA, ACE, NOS3
15halothane43 49 28 1211.9MB, ADRB2, HSPA1A, PIK3C2A, HIF1A
16radicicol43 59 1210.7HIF1A, NOS3, HSPA1A, VEGFA
17thapsigargin43 599.7BDKRB2, NOS3, HSPA1A, EDN1, CCK, HIF1A
18carvedilol43 49 28 1211.7NOS3, AGTR1, VEGFA, ACE, ADRB2, EDN1
19candesartan43 49 28 1211.7BDKRB2, HIF1A, ACE, NOS3, VEGFA, AGTR1
20nitroglycerin43 129.6EDN1, AGTR1, PIK3C2A, HIF1A, NOS3, ACE
21geldanamycin43 49 59 1211.6VHL, VEGFA, HSPA1A, HIF1A, NOS3
22epinephrine43 24 1210.5AGTR1, ADRB2, HSPA1A, MB, PIK3C2A, EDN1
23atorvastatin43 49 28 24 1212.5PIK3C2A, ACE, NOS3, EDN1, VEGFA
24pge2438.4MB, EDN1, VEGFA, BDKRB2, ADRB2, CCK
25sodium nitroprusside438.3PIK3C2A, EDN1, BDKRB2, HIF1A, AGTR1, MB
26genistein43 28 59 2 24 1213.1AGTR1, BDKRB2, NOS3, FLT1, HIF1A, EDN1
27phosphoinositide438.1ADRB2, BDKRB2, AGTR1, PIK3C2A, EDN1, HIF1A
28actinomycin d438.0VEGFA, AGTR1, VHL, NOS3, HIF1A, HSPA1A
29prostacyclin438.0ACE, NOS3, AGTR1, FLT1, VEGFA, PIK3C2A
30phosphatidylinositol438.0EDN1, HIF1A, FLT1, VHL, BDKRB2, AGTR1
31sb 20358043 598.9EDN1, AGTR1, NOS3, FLT1, HIF1A, HSPA1A
32glutamate437.9CCK, PIK3C2A, ADRB2, NOS3, MB, ENO2
33potassium43 24 129.8AGTR1, HSPA1A, ENO2, VHL, ACE, ADRB2
34pd 98,059437.8HSPA1A, ENO2, BDKRB2, NOS3, EDN1, HIF1A
35doxorubicin43 49 129.8NOS3, HIF1A, FLT1, VEGFA, PIK3C2A, MB
36sodium43 248.7AGTR1, ENO2, BDKRB2, ACE, HSPA1A, PIK3C2A
37acetylcholine43 49 28 24 1211.5ADRB2, EDN1, PIK3C2A, CCK, ACE, NOS3
38arginine437.5HSPA1A, PIK3C2A, EDN1, HIF1A, MB, ADRB2
39dexamethasone43 49 28 1210.4ENO2, CCK, BDKRB2, HIF1A, HSPA1A, VEGFA
40norepinephrine43 24 129.3ACE, MB, PIK3C2A, CCK, ADRB2, EDN1
41superoxide43 248.3PIK3C2A, HSPA1A, HIF1A, FLT1, AGTR1, ADRB2
42cisplatin43 49 59 1210.0PIK3C2A, VEGFA, HSPA1A, HIF1A, FLT1, MB
43creatinine436.9PIK3C2A, ENO2, ACE, AGTR1, BDKRB2, EDN1
44estrogen436.9HSPA1A, ENO2, HIF1A, FLT1, ADRB2, VHL
45glucose436.8VHL, ADRB2, CCK, HIF1A, HSPA1A, PIK3C2A
46nitric oxide43 24 128.6EDN1, ENO2, AGTR1, BDKRB2, NOS3, VHL
47calcium43 49 24 129.5EDN1, ENO2, BDKRB2, AGTR1, NOS3, VHL
48oxygen43 247.4PIK3C2A, ENO2, MB, NOS3, VHL, ADRB2
49tyrosine436.3HIF1A, PIK3C2A, ENO2, FLT1, ADRB2, CCK
50vegf436.1EDN1, PIK3C2A, VEGFA, VHL, NOS3, ADRB2

GO Terms for genes affiliated with Acute Mountain Sickness

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Cellular components related to Acute Mountain Sickness according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endosomeGO:00057689.1BDKRB2, ACE, ADRB2, FLT1
2extracellular spaceGO:00056157.4EDN1, VEGFA, FLT1, CCK, ACE, ENO2
3plasma membraneGO:00058867.3FLT1, ADRB2, ACE, NOS3, ENO2, BDKRB2

Biological processes related to Acute Mountain Sickness according to GeneCards Suite gene sharing:

(show all 30)
idNameGO IDScoreTop Affiliating Genes
1regulation of systemic arterial blood pressure by renin-angiotensinGO:000308110.2AGTR1, ACE
2regulation of sodium ion transportGO:000202810.2NOS3, ADRB2
3arachidonic acid secretionGO:005048210.2ACE, BDKRB2
4regulation of systemic arterial blood pressure by endothelinGO:000310010.1NOS3, EDN1
5positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling paGO:005148210.1EDN1, AGTR1
6vasoconstrictionGO:004231010.1BDKRB2, EDN1
7positive regulation of chemokine-mediated signaling pathwayGO:007010110.0HIF1A, EDN1
8brown fat cell differentiationGO:005087310.0MB, ADRB2
9regulation of vasodilationGO:004231210.0ADRB2, ACE, AGTR1
10positive regulation of receptor biosynthetic processGO:001087010.0EDN1, HIF1A
11positive regulation of cytosolic calcium ion concentrationGO:00072049.9EDN1, BDKRB2, AGTR1
12regulation of sensory perception of painGO:00519309.8CCK, EDN1
13positive regulation of transcription from RNA polymerase II promoter in response to hypoxiaGO:00614199.7HIF1A, VEGFA
14positive regulation of erythrocyte differentiationGO:00456489.7HIF1A, HSPA1B
15cell surface receptor signaling pathwayGO:00071669.7EDN1, ADRB2, BDKRB2
16dopaminergic neuron differentiationGO:00715429.7VEGFA, HIF1A
17regulation of vasoconstrictionGO:00192299.6AGTR1, BDKRB2, ACE, EDN1
18cellular response to vascular endothelial growth factor stimulusGO:00359249.6FLT1, VEGFA
19positive regulation of neuroblast proliferationGO:00020529.5HIF1A, VEGFA
20kidney developmentGO:00018229.5VEGFA, ACE, AGTR1
21regulation of transcription from RNA polymerase II promoter in response to hypoxiaGO:00614189.5VHL, HIF1A, VEGFA
22cellular response to hypoxiaGO:00714569.5VEGFA, HIF1A, VHL
23patterning of blood vesselsGO:00015699.4FLT1, VEGFA, EDN1
24positive regulation of MAP kinase activityGO:00434069.4EDN1, VEGFA, FLT1
25positive regulation of vascular endothelial growth factor receptor signaling pathwayGO:00309499.4FLT1, HIF1A, VEGFA
26positive regulation of cell migrationGO:00303359.3FLT1, VEGFA, EDN1
27response to hypoxiaGO:00016669.2EDN1, VEGFA, HIF1A, MB
28vascular endothelial growth factor receptor signaling pathwayGO:00480109.1FLT1, VEGFA
29positive regulation of angiogenesisGO:00457669.0VEGFA, HIF1A, FLT1, NOS3
30positive regulation of cell proliferationGO:00082849.0EDN1, VEGFA, FLT1, CCK

Molecular functions related to Acute Mountain Sickness according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1bradykinin receptor bindingGO:00317119.5ACE, AGTR1
2protein heterodimerization activityGO:00469828.9AGTR1, BDKRB2, HIF1A, VEGFA
3protein bindingGO:00055156.3AGTR1, EDN1, VEGFA, HSPA1B, HIF1A, FLT1

Products for genes affiliated with Acute Mountain Sickness

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Sources for Acute Mountain Sickness

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet