MCID: ACT115
MIFTS: 27

Acute Myeloid Leukemia, Adult malady

Genetic diseases, Rare diseases, Immune diseases, Blood diseases, Cancer diseases categories

Summaries for Acute Myeloid Leukemia, Adult

About this section


MalaCards based summary: Acute Myeloid Leukemia, Adult, also known as leukemia acute myelogenous, is related to core binding factor acute myeloid leukemia and myelodysplastic syndrome. An important gene associated with Acute Myeloid Leukemia, Adult is GATA2 (GATA binding protein 2). The drugs cyclophosphamide and etoposide have been mentioned in the context of this disorder. Affiliated tissues include myeloid.

Aliases & Classifications for Acute Myeloid Leukemia, Adult

About this section
Sources:
41NIH Rare Diseases, 43Novoseek, 22GTR, 60UMLS
See all sources

Acute Myeloid Leukemia, Adult, Aliases & Descriptions:

Name: Acute Myeloid Leukemia, Adult 41
Leukemia Acute Myelogenous 41 22
Aml Adult 41 43
Adult Acute Myeloid Leukemia Without Maturation 60
Adult Acute Myeloblastic Leukemia 60
Acute Non-Lymphocytic Leukemia 41
 
Adult Acute Myeloid Leukemia 41
Leukemia, Myelocytic, Acute 60
Acute Granulocytic Leukemia 41
Acute Myelogenous Leukemia 41
Acute Myeloid Leukemia 41
Aml 41


Classifications:



Related Diseases for Acute Myeloid Leukemia, Adult

About this section

Diseases in the Myeloid Leukemia family:

Leukemia, Acute Myeloid Leukemia, Chronic Myeloid
Subacute Myeloid Leukemia acute myeloid leukemia, adult
Npm1-Related Acute Myeloid Leukemia Inherited Acute Myeloid Leukemia
'acute Myeloid Leukemia with T(9;11)(p22;q23)' 'acute Myeloid Leukemia with T(6;9)(p23;q34)'

Diseases related to Acute Myeloid Leukemia, Adult via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 337)
idRelated DiseaseScoreTop Affiliating Genes
1core binding factor acute myeloid leukemia11.0
2myelodysplastic syndrome10.9
3leukemia10.7
4familial acute myeloid leukemia with mutated cebpa10.7
5acute myeloid leukemia with multilineage dysplasia10.7
6myelofibrosis10.7
7hematopoietic stem cell transplantation10.6
8mediastinitis10.6
9sarcoma10.6
10essential thrombocythemia10.6
11neutropenia10.5
12leukostasis10.5
13leukemia, acute promyelocytic10.5
14chronic lymphocytic leukemia10.5
15'acute myeloid leukemia with t(9;11)(p22;q23)'10.5
16leukemia, acute myeloid10.5
17platelet disorder, familial, with associated myeloid malignancy10.5
18familial platelet disorder with propensity to acute myelogenous leukemia10.5
19central nervous system disease10.5
20nervous system disease10.5
21blastic plasmacytoid dendritic cell10.5
22blindness10.5
23inherited acute myeloid leukemia10.5
24acute myeloid leukemia with t(8;16)(p11;p13) translocation10.5
25'acute myeloid leukemia with t(6;9)(p23;q34)'10.5
26acute myeloid leukemia with 11q23 abnormalities10.5
27severe congenital neutropenia10.4
28diabetes insipidus10.4
29hidradenitis10.4
30lymphoblastic leukemia10.4
31acute febrile neutrophilic dermatosis10.4
32mastocytosis10.4
33zygomycosis10.4
34endotheliitis10.4
35refractory anemia10.4
36acute erythroid leukemia10.4
37sinusitis10.4
38mast-cell leukemia10.4
39obstructive jaundice10.4
40thrombophlebitis10.4
41uveitis10.4
42acute myeloid leukemia, childhood10.4
43acute myeloid leukemia, susceptibility, gata2-related10.4
44npm1-related acute myeloid leukemia10.4
45hypoxia10.4
46acute myeloid leukemia and myelodysplastic syndromes related to radiation10.4
47acute myeloid leukemia with cebpa somatic mutations10.4
48'acute myeloid leukemia with inv3(p21;q26.2) or t(3;3)(p21;q26.2)'10.4
49'megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13)'10.4
50acute myeloid leukemia with npm1 somatic mutations10.4

Graphical network of the top 20 diseases related to Acute Myeloid Leukemia, Adult:



Diseases related to acute myeloid leukemia, adult

Symptoms for Acute Myeloid Leukemia, Adult

About this section

Drugs & Therapeutics for Acute Myeloid Leukemia, Adult

About this section

Drug clinical trials:

Search ClinicalTrials for Acute Myeloid Leukemia, Adult

Search NIH Clinical Center for Acute Myeloid Leukemia, Adult

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Acute Myeloid Leukemia, Adult

About this section

Genetic tests related to Acute Myeloid Leukemia, Adult:

id Genetic test Affiliating Genes
1 Acute Myelogenous Leukemia22

Anatomical Context for Acute Myeloid Leukemia, Adult

About this section

MalaCards organs/tissues related to Acute Myeloid Leukemia, Adult:

31
Myeloid

Animal Models for Acute Myeloid Leukemia, Adult or affiliated genes

About this section

Publications for Acute Myeloid Leukemia, Adult

About this section

Variations for Acute Myeloid Leukemia, Adult

About this section

Clinvar genetic disease variations for Acute Myeloid Leukemia, Adult:

6
id Gene Variation Type Significance SNP ID Assembly Location
1GATA2NM_001145661.1(GATA2): c.1061C> T (p.Thr354Met)single nucleotide variantPathogenic, risk factorrs387906631GRCh37Chr 3, 128200744: 128200744

Expression for genes affiliated with Acute Myeloid Leukemia, Adult

About this section
Search GEO for disease gene expression data for Acute Myeloid Leukemia, Adult.

Pathways for genes affiliated with Acute Myeloid Leukemia, Adult

About this section

Compounds for genes affiliated with Acute Myeloid Leukemia, Adult

About this section

GO Terms for genes affiliated with Acute Myeloid Leukemia, Adult

About this section

Products for genes affiliated with Acute Myeloid Leukemia, Adult

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Acute Myeloid Leukemia, Adult

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet