MCID: ACT075
MIFTS: 60

Acute Myocardial Infarction malady

Categories: Cardiovascular diseases, Genetic diseases

Aliases & Classifications for Acute Myocardial Infarction

Aliases & Descriptions for Acute Myocardial Infarction:

Name: Acute Myocardial Infarction 38 12 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9408
ICD10 33 I21.3 I21
ICD9CM 35 410 410.9 410.90
NCIt 47 C35204
UMLS 69 C0155626

Summaries for Acute Myocardial Infarction

MalaCards based summary : Acute Myocardial Infarction is related to myocardial infarction and essential thrombocythemia, and has symptoms including angina pectoris and chest pain. An important gene associated with Acute Myocardial Infarction is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Dilated cardiomyopathy. The drugs Pravastatin and Abciximab have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and brain, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Acute Myocardial Infarction

Diseases in the Myocardial Infarction family:

Myocardial Infarction 2 Acute Myocardial Infarction
Posterior Myocardial Infarction Myocardial Infarction, Susceptibility to, 1

Diseases related to Acute Myocardial Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 371)
id Related Disease Score Top Affiliating Genes
1 myocardial infarction 30.6 ACE ADRB1 CKB CRP EDN1 F3
2 essential thrombocythemia 30.4 F3 SERPINC1 VWF
3 prostatic hypertrophy 30.0 F3 SELP VWF
4 influenza 30.0 F3 SERPINC1 SERPINF2
5 silent myocardial infarction 29.8 MB PIK3C2A PLAT SERPINC1
6 tuberculosis 29.8 ACE PIK3C2A TNNI3
7 toxic myocarditis 29.7 ACE ADRB1 CRP NPPB
8 lupus erythematosus 29.6 ACE CRP F3 MB PLAT SELP
9 pericarditis 29.4 ACE CRP EDN1 F3 MMP9 PLAT
10 subendocardial infarction acute myocardial infarction 12.1
11 strictly posterior acute myocardial infarction 12.0
12 coronary artery disease, autosomal dominant, 1 11.2
13 acute inferoposterior infarction 11.1
14 acute inferolateral myocardial infarction 11.1
15 acute anterolateral myocardial infarction 11.1
16 coronary artery disease, autosomal dominant, 2 11.0
17 hyperlipidemia type 3 11.0
18 coronary thrombosis 10.8
19 cardiogenic shock 10.6
20 endotheliitis 10.5
21 cardiac rupture 10.4
22 thrombosis 10.4
23 aneurysm 10.4
24 joint disorders 10.4 ACE CRP NPPB
25 angina pectoris 10.4
26 syringomelia hyperkeratosis 10.4 ACE NPPA NPPB
27 citrulline transport defect 10.4 CRP EDN1 NPPB
28 melorheostosis 10.3 ACE PLAT SERPINC1
29 suppurative otitis media 10.3 ACE NPPA NPPB
30 myxoid chondrosarcoma 10.3 NPPB PIK3C2A PLAT
31 myopia 10.3 ACE EDN1 NPPA
32 petrositis 10.3 ACE EDN1 NPPB
33 brazilian hemorrhagic fever 10.3 PLAT SERPINC1 SERPINE1
34 right bundle branch block 10.3
35 arcus senilis 10.3 CRP F3 SERPINE1
36 uterine inflammatory disease 10.3 EDN1 SERPINE1
37 focal dystonia 10.3 ACE CRP SELP
38 pancreas lymphoma 10.3 CRP NPPB TNNT2
39 hereditary endotheliopathy, retinopathy, nephropathy, and stroke 10.3 F3 SELP SERPINC1
40 intestinal disaccharidase deficiency 10.3 CRP F3 SERPINC1
41 bullous skin disease 10.3 ACE SERPINC1 SERPINE1
42 microphthalmia, isolated, with coloboma 7 10.3 ACE MB PIK3C2A
43 colonic lymphangioma 10.3 ACE PIK3C2A
44 familial periodic paralysis 10.3 ACE CRP NPPB
45 periosteal chondrosarcoma 10.3 MB SERPINC1 SERPINE1
46 voyeurism 10.3 MB PLAT TNNI3
47 subclavian artery aneurysm 10.3 F3 SELP SERPINE1
48 perrault syndrome 10.3 PLAT SELP SERPINE1
49 myocardial infarction 2 10.3
50 glomerulonephritis 10.3 MB TNNI3 TNNT2

Comorbidity relations with Acute Myocardial Infarction via Phenotypic Disease Network (PDN): (show all 22)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Cardiac Arrest
Chronic Kidney Failure Chronic Myocardial Ischemia
Decubitus Ulcer Deficiency Anemia
Familial Atrial Fibrillation Generalized Atherosclerosis
Heart Disease Hypertension, Essential
Intermediate Coronary Syndrome Ischemic Heart Disease
Kidney Disease Left Ventricular Outflow Tract Obstruction
Mitral Valve Disease Peripheral Vascular Disease
Protein-Energy Malnutrition Respiratory Failure
Schizophreniform Disorder Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Acute Myocardial Infarction:



Diseases related to Acute Myocardial Infarction

Symptoms & Phenotypes for Acute Myocardial Infarction

UMLS symptoms related to Acute Myocardial Infarction:


angina pectoris, chest pain

MGI Mouse Phenotypes related to Acute Myocardial Infarction:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.36 ACE ADRB1 CRP EDN1 F3 FABP3
2 homeostasis/metabolism MP:0005376 10.25 MMP9 NPPA PIK3C2A PLAT SELP SERPINC1
3 growth/size/body region MP:0005378 10.18 EDN1 F3 MB MMP9 PIK3C2A PLAT
4 mortality/aging MP:0010768 10.13 SELP SERPINC1 SERPINE1 ACE ADRB1 EDN1
5 hematopoietic system MP:0005397 10.11 ACE F3 MB MMP9 NPPA PIK3C2A
6 muscle MP:0005369 9.85 ADRB1 EDN1 F3 FABP3 MB MMP9
7 renal/urinary system MP:0005367 9.56 ACE EDN1 MMP9 NPPA PIK3C2A SELP
8 respiratory system MP:0005388 9.17 F3 MB MMP9 PLAT SELP SERPINE1

Drugs & Therapeutics for Acute Myocardial Infarction

Drugs for Acute Myocardial Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 645)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pravastatin Approved Phase 4,Phase 2 81093-37-0 54687
2
Abciximab Approved Phase 4,Phase 3,Phase 2 143653-53-6
3
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
4
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 22916-47-8 4189
5
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
6
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-78-2 2244
7
Bivalirudin Approved, Investigational Phase 4,Phase 3 128270-60-0 16129704
8
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 772 46507594
9
Tenecteplase Approved Phase 4,Phase 3,Phase 2 191588-94-0
10
Tirofiban Approved Phase 4,Phase 3,Phase 2 144494-65-5 60947
11
Colchicine Approved Phase 4,Phase 3,Phase 2 64-86-8 6167 2833
12
Ticagrelor Approved Phase 4,Phase 3,Phase 2 274693-27-5 9871419
13
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 55142-85-3 5472
14
Nicorandil Approved Phase 4,Phase 3 65141-46-0 47528
15
Desflurane Approved Phase 4 57041-67-5 42113
16
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
17
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
18
Insulin Glargine Approved Phase 4,Phase 3 160337-95-1
19
Metformin Approved Phase 4,Phase 2,Phase 3 657-24-9 14219 4091
20
Zinc Approved Phase 4,Phase 3,Phase 1 7440-66-6 32051 23994
21
Menthol Approved Phase 4,Phase 2,Phase 3,Phase 1 2216-51-5 16666
22
Etanercept Approved, Investigational Phase 4 185243-69-0
23
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2 137862-53-4 60846
24
Citalopram Approved Phase 4,Phase 2 59729-33-8 2771
25
Ramipril Approved Phase 4,Phase 2,Phase 3 87333-19-5 5362129
26
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
27
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3 73590-58-6 4594
28
Pantoprazole Approved Phase 4,Phase 3 102625-70-7 4679
29
Benzocaine Approved Phase 4,Phase 2,Phase 3 1994-09-7, 94-09-7 2337
30
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
31
Pioglitazone Approved, Investigational Phase 4,Phase 3 111025-46-8 4829
32
Verapamil Approved Phase 4 52-53-9 2520
33
Lenograstim Approved Phase 4,Phase 2,Phase 3,Phase 1 135968-09-1
34
Paclitaxel Approved, Vet_approved Phase 4,Phase 2,Phase 3 33069-62-4 36314
35
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
36
Adenosine Approved, Investigational Phase 4,Phase 2,Phase 3 58-61-7 60961
37
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2 188627-80-7 123610
38
Exenatide Approved, Investigational Phase 4,Phase 3 141758-74-9 15991534
39
Nitric Oxide Approved Phase 4,Phase 2,Phase 3,Phase 1 10102-43-9 145068
40
Rivaroxaban Approved Phase 4,Phase 2,Phase 3 366789-02-8
41
Apixaban Approved Phase 4,Phase 2,Phase 3 503612-47-3 10182969
42
Warfarin Approved Phase 4,Phase 3 81-81-2 6691 54678486
43
Nitroprusside Approved Phase 4,Phase 2,Phase 3 15078-28-1 11963622
44
Bezafibrate Approved Phase 4 41859-67-0 39042
45
Streptokinase Approved Phase 4,Phase 3 9002-01-1
46
Diltiazem Approved Phase 4 42399-41-7 39186
47
Nitroglycerin Approved, Investigational Phase 4,Phase 3 55-63-0 4510
48
Cilostazol Approved Phase 4,Phase 3 73963-72-1 2754
49
Antipyrine Approved Phase 4 60-80-0 2206
50
Aminophylline Approved Phase 4 317-34-0 9433

Interventional clinical trials:

(show top 50) (show all 1803)
id Name Status NCT ID Phase
1 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4
2 Sirolimus Eluting Stenting in Acute Myocardial Infarction Unknown status NCT00288210 Phase 4
3 Efficacy of Thrombosuction in Primary Percutaneous Coronary Intervention of Acute Myocardial Infarction Unknown status NCT01156662 Phase 4
4 Anti-Restenosis After AMI by Erythropoietin Unknown status NCT00423020 Phase 4
5 IRIS : Use of Implantable Defibrillator in High-Risk Patients Early After Acute Myocardial Infarction Unknown status NCT00157768 Phase 4
6 Microvascular Reperfusion Utilizing Sonothrombolysis in Acute Myocardial Infarction (MRUSMI TRIAL) Unknown status NCT02170103 Phase 4
7 Comparison of Primary PCI vs. Post-thrombolysis PCI as Reperfusion Strategies in STEMI Unknown status NCT02268669 Phase 4
8 Treating Acute MI Patients With Aggrastat on Their Way to Hospital Unknown status NCT00300833 Phase 4
9 N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure Unknown status NCT00692718 Phase 4
10 Colchicine in ST-elevation Myocardial Infarction Unknown status NCT01936285 Phase 4
11 Multicentre 2x2 Factorial Randomised Study Comparing Tirofiban Versus Abciximab and SES Versus BMS in AMI Unknown status NCT00229515 Phase 4
12 Dissecting the Role of Distal Embolization of Athero-thrombotic Material in Primary PCI: the ThrombOticBurden and mIcrovAscularobStruction (TOBIAS) Study. Unknown status NCT01914055 Phase 4
13 Post-MI PET Scan Imaging of Inflammation Unknown status NCT02281305 Phase 4
14 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4
15 Effect of Nicorandil for the Patients of Acute ST Segment Elevation Myocardial Infarction Unknown status NCT02435797 Phase 4
16 Efficacy Study of Combined Prasugrel and Bivalirudin Versus Clopidogrel and Heparin in Myocardial Infarction Unknown status NCT00976092 Phase 4
17 Vitamin D and Inflammatory Cytokine Levels After Acute Myocardial Infraction (MI) Unknown status NCT01115842 Phase 4
18 Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab Unknown status NCT01383785 Phase 4
19 Ticagrelor and Clopidogrel on Reperfusion in Patients With AMI Unknown status NCT02233790 Phase 4
20 Desflurane-induced Myocardial Protection Unknown status NCT02019797 Phase 4
21 Can Insulin Glargine Improve Myocardial Function in Patients With T2D and Coronary Artery Disease (CAD) Unknown status NCT01035528 Phase 4
22 CT Coronary Angiogram Versus Traditional Care in Emergency Department Assessment of Potential ACS Unknown status NCT00933400 Phase 4
23 A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction Unknown status NCT01942070 Phase 4
24 Early Routine Catheterisation After Alteplase Fibrinolysis vs. Primary PCI in Acute ST-elevation Myocardial Infarct Unknown status NCT01930682 Phase 4
25 Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction Unknown status NCT01372930 Phase 4
26 Thrombus Aspiration During Percutaneous Coronary Intervention in Acute Non-ST-elevation Myocardial Infarction Study Unknown status NCT01013038 Phase 4
27 Effects of Intensive Statin Treatment on Left Ventricular Function Unknown status NCT01936103 Phase 4
28 Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome Unknown status NCT01372839 Phase 4
29 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4
30 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4
31 Clopidogrel Reloading in Patients With NSTEACS Undergoing Percutaneous Coronary Intervention on Chronic Clopidogrel Therapy Unknown status NCT01572129 Phase 4
32 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4
33 Telmisartan Versus Ramipril After Acute Coronary Syndrome Unknown status NCT00702936 Phase 4
34 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4
35 Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN) Unknown status NCT01735227 Phase 4
36 Comparing Ticagrelor and Clopidogrel Pharmacodynamics After Thrombolysis Unknown status NCT02048085 Phase 4
37 Efficacy of Ticagrelor vs Clopidogrel in High-risk NSTE-ACS Patients Undergoing Early PCI Unknown status NCT02201667 Phase 4
38 Optimizing Infarct Size by Transforming Emergent Stenting Into an Elective Procedure Study Unknown status NCT01462188 Phase 4
39 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4
40 Customized Choice of Oral P2Y12 Receptor Blocker Unknown status NCT01477775 Phase 4
41 Effect of Conditioning on Myocardial Damage in STEMI Unknown status NCT02158468 Phase 4
42 Colchicine for Acute Coronary Syndromes Unknown status NCT01906749 Phase 4
43 Comparative Phase IV Study: Efficacy And Safety of TiTAN2 Versus COBALT-CHROME Stents- EVIDENCEII Unknown status NCT01918150 Phase 4
44 Intensive Lipid Lowering Treatment in Non-ST-elevation Acute Coronary Syndrome (NSTE-ACS) Patients Unknown status NCT01040936 Phase 4
45 Randomized Trial of Creatine-kinase Leak After Rosuvastatin At the Time of Percutaneous Coronary Intervention Unknown status NCT01968577 Phase 4
46 Diagnosis and Treatment of ACS in the ED: The Impact of Rapid Bedside cTnI Testing on Outcomes Unknown status NCT00222352 Phase 4
47 Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing Unknown status NCT00698607 Phase 4
48 Effect of Modifying Anti-platelet Treatment to Ticagrelor in Patients With Diabetes and Low Response to Clopidogrel Unknown status NCT01643031 Phase 4
49 Cost-effectiveness of Genotype Guided Treatment With Antiplatelet Drugs in STEMI Patients: Optimization of Treatment Unknown status NCT01761786 Phase 4
50 Normoglycemia and Neurological Outcome Unknown status NCT01137773 Phase 4

Search NIH Clinical Center for Acute Myocardial Infarction

Genetic Tests for Acute Myocardial Infarction

Anatomical Context for Acute Myocardial Infarction

MalaCards organs/tissues related to Acute Myocardial Infarction:

39
Heart, Endothelial, Brain, Monocytes, Testes, Neutrophil, Bone

Publications for Acute Myocardial Infarction

Articles related to Acute Myocardial Infarction:

(show top 50) (show all 2796)
id Title Authors Year
1
Impact of Morning Onset on the Incidence of Recurrent Acute Coronary Syndrome and Progression of Coronary Atherosclerosis in Acute Myocardial Infarction. ( 28090071 )
2017
2
Rationale and Design of a Clinical Trial to Evaluate the Safety and Efficacy of Intracoronary Infusion of Allogeneic Human CARdiac stEm Cells in Patients with Acute Myocardial Infarction and Left Ventricular Dysfunction: The Randomized Multicenter Double-Blind Controlled CAREMI Trial. ( 28533209 )
2017
3
Benefits of Statin Therapy in Patients With Acute Myocardial Infarction With Serum Low-Density Lipoprotein Cholesterol a8o 50A mg/dl. ( 28532771 )
2017
4
Cardiac remodeling following reperfused acute myocardial infarction is linked to the concomitant evolution of vascular function as assessed by cardiovascular magnetic resonance. ( 28063459 )
2017
5
Inferior Wall Acute Myocardial Infarction: Not as Preload Dependent as Once Thought? ( 28089058 )
2017
6
Letter by Koh Regarding Article, "Effect of Omega-3 Acid Ethyl Esters on Left Ventricular Remodeling After Acute Myocardial Infarction: The OMEGA-REMODEL Randomized Clinical Trial". ( 28069716 )
2017
7
Circulating MicroRNA-145 is Associated with Acute Myocardial Infarction and Heart Failure. ( 28051023 )
2017
8
Moving Beyond SHOCK: New Paradigms in the Management of Acute Myocardial Infarction Complicated by Cardiogenic Shock. ( 28024554 )
2017
9
Cardiac Troponin T: Smaller Molecules in Patients with End-Stage Renal Disease than after Onset of Acute Myocardial Infarction. ( 28073901 )
2017
10
Trimethylamine N-oxide and Risk Stratification after Acute Myocardial Infarction. ( 28062632 )
2017
11
Incidence of atrial fibrillation detected by continuous rhythm monitoring after acute myocardial infarction in patients with preserved left ventricular ejection fraction: results of the ARREST study. ( 28069838 )
2017
12
The potential of optimizing prehospital triage of patients with suspected acute myocardial infarction using high-sensitivity cardiac troponin T and copeptin. ( 27903076 )
2017
13
Does This Patient Have Acute Myocardial Infarction? ( 28062638 )
2017
14
Changes in One-Year Mortality in Elderly Patients Admitted with Acute Myocardial Infarction in Relation with Early Management. ( 28065766 )
2017
15
Correlation and prognostic role of neutrophil to lymphocyte ratio and SYNTAX score in patients with acute myocardial infarction treated with percutaneous coronary intervention: A six-year experience. ( 28529092 )
2017
16
Cardiac and Noncardiac Causes of Long-Term Mortality in ST-Segment-Elevation Acute Myocardial Infarction Patients Who Underwent Primary Percutaneous Coronary Intervention. ( 28073848 )
2017
17
History of erectile dysfunction as a predictor of poor physical performance after an acute myocardial infarction. ( 28067536 )
2017
18
Prognostic value of total triiodothyronine and free thyroxine levels for the heart failure in patients with acute myocardial infarction. ( 28073241 )
2017
19
Long-term outcome and risk prediction in patients suffering acute myocardial infarction complicated by post-infarction cardiac rupture. ( 27847155 )
2017
20
Expression pattern of genome-scale long noncoding RNA following acute myocardial infarction in Chinese Uyghur patients. ( 28418905 )
2017
21
Response by Heydari et al to Letter Regarding Article, "Effect of Omega-3 Acid Ethyl Esters on Left Ventricular Remodeling After Acute Myocardial Infarction: The OMEGA-REMODEL Randomized Clinical Trial". ( 28069718 )
2017
22
COLIN trial: Value of colchicine in the treatment of patients with acute myocardial infarction and inflammatory response. ( 28065445 )
2017
23
Educational level and 30-day outcomes after hospitalization for acute myocardial infarction in Italy. ( 28069004 )
2017
24
The Neuroprotective Strategic Analysis for Patients with Acute Myocardial Infarction Combined with Hypoxic Ischemic Encephalopathy in ICU. ( 28065791 )
2017
25
Cardiac Cell Therapies for the Treatment of Acute Myocardial Infarction: A Meta-Analysis from Mouse Studies. ( 28535507 )
2017
26
Letter by NAogele Regarding Article, "Effect of Omega-3 Acid Ethyl Esters on Left Ventricular Remodeling After Acute Myocardial Infarction: The OMEGA-REMODEL Randomized Clinical Trial". ( 28069717 )
2017
27
Is type D personality an independent risk factor for recurrent myocardial infarction or all-cause mortality in post-acute myocardial infarction patients? ( 28071958 )
2017
28
A case of acute myocardial infarction after successful transcatheter closure of ventricular septal defect. ( 28533728 )
2016
29
A case of acute myocardial infarction due to cardiovascular syphilis with aortic regurgitation and bilateral coronary ostial stenosis. ( 27873284 )
2016
30
Myocardial Production of Plasminogen Activator Inhibitor-1 is Associated with Coronary Endothelial and Ventricular Dysfunction after Acute Myocardial Infarction. ( 26632165 )
2016
31
A comparative study of time-specific oxidative stress after acute myocardial infarction in patients with and without diabetes mellitus. ( 27216220 )
2016
32
sMICA as novel and early predictors for acute myocardial infarction. ( 27306684 )
2016
33
Circulating miR-221-3p as a novel marker for early prediction of acute myocardial infarction. ( 27374153 )
2016
34
Effective Factors in Door-to-Needle Time for Streptokinase Administration in Patients With Acute Myocardial Infarction Admitted to the Emergency Department. ( 27218043 )
2016
35
Diagnostic value of miR-30d-5p and miR-125b-5p in acute myocardial infarction. ( 27176713 )
2016
36
The use of very low concentrations of high sensitivity troponin T to rule out acute myocardial infarction using a single blood test. ( 27178492 )
2016
37
Acute myocardial infarction as the initial thrombotic event of thrombotic thrombocytopenic purpura. ( 26757016 )
2016
38
Methylenetetrahydrofolate Dehydrogenase 1 Polymorphisms Modify the Associations of Plasma Glycine and Serine With Risk of Acute Myocardial Infarction in Patients With Stable Angina Pectoris in WENBIT (Western Norway B Vitamin Intervention Trial). ( 27872106 )
2016
39
Clinical outcomes of drug-eluting stents versus bare-metal stents in patients with cardiogenic shock complicating acute myocardial infarction. ( 27111168 )
2016
40
Factors Associated With Initial Prasugrel Versus Clopidogrel Selection for Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention: Insights From the Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) Study. ( 27663414 )
2016
41
Acute myocardial infarction with isolated congenitally corrected transposition of the great arteries. ( 27034557 )
2016
42
TCT-145 Rheolytic Thrombectomy for Acute Myocardial Infarction Complicated by Cardiogenic Shock. ( 27970309 )
2016
43
Endogenous C1-inhibitor production and expression in the heart after acute myocardial infarction. ( 26476955 )
2016
44
Isolated congenitally corrected transposition of the great arteries with dextroversion discovered incidentally in a patient with cocaine-induced acute myocardial infarction. ( 27034558 )
2016
45
Differential Impact of Hyperglycemia in Critically Ill Patients: Significance in Acute Myocardial Infarction but Not in Sepsis? ( 27657056 )
2016
46
Quality indicators for acute myocardial infarction. ( 28087744 )
2016
47
Rationale and design of Apo-I Event Reduction in Ischemic Syndromes I (AEGIS-I): A phase 2b, randomized, placebo-controlled, dose-ranging trial to investigate the safety and tolerability of CSL112, a reconstituted, infusible, human apoA-I, after acute myocardial infarction. ( 27659879 )
2016
48
Prognostic Significance of Right Bundle Branch Block for Patients with Acute Myocardial Infarction: A Systematic Review and Meta-Analysis. ( 27017617 )
2016
49
The Time Course of Markers of Neutrophil Extracellular Traps in Patients Undergoing Revascularisation for Acute Myocardial Infarction or Stable Angina Pectoris. ( 28074081 )
2016
50
Hospital triage of acute myocardial infarction: Is admission to the coronary care unit still necessary? ( 27179737 )
2016

Variations for Acute Myocardial Infarction

Copy number variations for Acute Myocardial Infarction from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 210497 6 30400000 36600000 Amplification C4B Acute myocardial infarction

Expression for Acute Myocardial Infarction

LifeMap Discovery
Genes differentially expressed in tissues of Acute Myocardial Infarction patients vs. healthy controls: 35
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1 EGR3 early growth response 3 Blood + 5.52 0.000
2 LOC286058 uncharacterized LOC286058 Blood + 4.73 0.000
3 CXCL8 chemokine (C-X-C motif) ligand 8 Blood + 3.51 0.004
4 LEP leptin Heart + 3.45 0.011
5 ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein Blood + 3.18 0.007
Search GEO for disease gene expression data for Acute Myocardial Infarction.

Pathways for Acute Myocardial Infarction

GO Terms for Acute Myocardial Infarction

Cellular components related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.93 ACE CRP EDN1 F3 MMP9 NPPA
2 extracellular exosome GO:0070062 9.77 ACE CKB CRP F3 FABP3 MB
3 extracellular matrix GO:0031012 9.72 F3 MMP9 PLAT SERPINE1 VWF
4 platelet alpha granule lumen GO:0031093 9.63 SERPINE1 SERPINF2 VWF
5 extracellular space GO:0005615 9.47 ACE CKB CRP EDN1 F3 FABP3
6 troponin complex GO:0005861 9.43 TNNI3 TNNT2
7 cardiac myofibril GO:0097512 9.4 TNNI3 TNNT2
8 Weibel-Palade body GO:0033093 9.37 EDN1 VWF
9 cardiac Troponin complex GO:1990584 9.26 TNNI3 TNNT2

Biological processes related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

(show all 18)
id Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.73 F3 PLAT SERPINC1 VWF
2 response to hypoxia GO:0001666 9.67 EDN1 MB NPPA PLAT
3 heart contraction GO:0060047 9.58 ACE TNNI3
4 hemostasis GO:0007599 9.58 F3 SERPINC1 VWF
5 regulation of vasodilation GO:0042312 9.57 ACE NPPB
6 positive regulation of urine volume GO:0035810 9.56 EDN1 NPPB
7 platelet degranulation GO:0002576 9.56 SELP SERPINE1 SERPINF2 VWF
8 positive regulation of renal sodium excretion GO:0035815 9.55 EDN1 NPPB
9 negative regulation of blood coagulation GO:0030195 9.54 EDN1 SERPINE1
10 negative regulation of fibrinolysis GO:0051918 9.52 SERPINE1 SERPINF2
11 receptor guanylyl cyclase signaling pathway GO:0007168 9.51 NPPA NPPB
12 regulation of blood vessel diameter GO:0097746 9.49 ACE NPPB
13 body fluid secretion GO:0007589 9.48 EDN1 NPPB
14 negative regulation of ATPase activity GO:0032780 9.46 TNNI3 TNNT2
15 fibrinolysis GO:0042730 9.33 PLAT SERPINE1 SERPINF2
16 negative regulation of plasminogen activation GO:0010757 9.32 SERPINE1 SERPINF2
17 regulation of blood vessel size GO:0050880 9.13 EDN1 NPPA NPPB
18 regulation of blood pressure GO:0008217 8.92 ACE EDN1 NPPA NPPB

Molecular functions related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.55 EDN1 NPPA NPPB PLAT SERPINE1
2 serine-type endopeptidase inhibitor activity GO:0004867 9.54 SERPINC1 SERPINE1 SERPINF2
3 glycoprotein binding GO:0001948 9.43 PLAT SELP VWF
4 protease binding GO:0002020 9.02 F3 SERPINC1 SERPINE1 SERPINF2 VWF
5 troponin C binding GO:0030172 8.96 TNNI3 TNNT2
6 protein binding GO:0005515 10.25 ADRB1 CKB CRP EDN1 F3 FABP3

Sources for Acute Myocardial Infarction

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