MCID: ACT075
MIFTS: 64

Acute Myocardial Infarction

Categories: Cardiovascular diseases, Genetic diseases

Aliases & Classifications for Acute Myocardial Infarction

MalaCards integrated aliases for Acute Myocardial Infarction:

Name: Acute Myocardial Infarction 37 12 51 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9408
ICD10 32 I21.3 I21
ICD9CM 34 410 410.9 410.90
NCIt 46 C35204
UMLS 69 C0155626

Summaries for Acute Myocardial Infarction

MalaCards based summary : Acute Myocardial Infarction is related to acute anterolateral myocardial infarction and coronary thrombosis, and has symptoms including chest pain and angina pectoris. An important gene associated with Acute Myocardial Infarction is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Dilated cardiomyopathy (DCM). The drugs Pravastatin and Abciximab have been mentioned in the context of this disorder. Affiliated tissues include heart, bone and bone marrow, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Acute Myocardial Infarction

Diseases in the Myocardial Infarction family:

Myocardial Infarction 2 Acute Myocardial Infarction
Posterior Myocardial Infarction

Diseases related to Acute Myocardial Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 406)
# Related Disease Score Top Affiliating Genes
1 acute anterolateral myocardial infarction 32.7 ACE PIK3C2A
2 coronary thrombosis 31.8 F3 PLAT SERPINC1 SERPINE1 VWF
3 cardiogenic shock 31.7 CRP NPPB PIK3C2A PLAT
4 myocarditis 31.1 MB NPPB TNNI3
5 thrombosis 30.8 F3 PLAT SELP SERPINC1 SERPINE1 VWF
6 ischemic heart disease 30.8 ACE CRP NPPB
7 coronary stenosis 30.7 ACE CRP SERPINE1 TNNI3 VWF
8 ischemia 30.7 ACE EDN1 MB PLAT SELP
9 coronary heart disease 1 30.7 ACE ADRB1 CRP SERPINE1
10 thrombocytosis 30.7 CRP F3 SELP SERPINC1
11 kawasaki disease 30.7 CRP MMP9 NPPB
12 pericarditis 30.7 CRP NPPB TNNT2
13 chronic kidney failure 30.6 ACE CRP EDN1 NPPB
14 heparin-induced thrombocytopenia 30.6 F3 SELP SERPINC1
15 essential thrombocythemia 30.6 F3 SELP SERPINE1 VWF
16 myocardial stunning 30.5 EDN1 SERPINC1 TNNI3 TNNT2
17 kidney disease 30.5 ACE EDN1 NPPA NPPB
18 thrombotic thrombocytopenic purpura 30.5 F3 SELP VWF
19 antiphospholipid syndrome 30.5 F3 PLAT SELP SERPINC1
20 endocarditis 30.4 CRP PIK3C2A SERPINC1 TNNI3
21 cardiac arrest 30.4 ACE CKB PIK3C2A TNNT2
22 syndrome of inappropriate antidiuretic hormone 30.4 ACE NPPA NPPB
23 purpura 30.4 CRP F3 SERPINC1 VWF
24 von willebrand's disease 30.4 F3 SELP VWF
25 angina pectoris 30.3 ACE CRP F3 PLAT SERPINC1 SERPINE1
26 systolic heart failure 30.3 ACE ADRB1 CRP NPPB
27 atrial fibrillation 30.3 ACE ADRB1 NPPA NPPB PLAT SELP
28 infective endocarditis 30.2 CRP SERPINE1 TNNI3
29 toxic myocarditis 30.2 NPPB PIK3C2A TNNI3
30 sleep apnea 30.2 ACE CRP EDN1 NPPB
31 carotid artery disease 30.2 ACE CRP MMP9
32 portal vein thrombosis 30.2 SELP SERPINC1 SERPINE1
33 pulmonary edema 30.2 ACE CRP EDN1 NPPB PIK3C2A SERPINC1
34 aortic coarctation 30.2 ACE ADRB1 EDN1
35 factor xiii deficiency 30.1 F3 SERPINE1 SERPINF2
36 pericardial effusion 30.1 CRP NPPA NPPB PIK3C2A
37 dressler's syndrome 30.1 CKB CRP PLAT
38 hypertrophic cardiomyopathy 30.0 ACE NPPB TNNI3 TNNT2
39 congestive heart failure 30.0 ACE ADRB1 EDN1 FABP3 NPPA NPPB
40 ischemic colitis 30.0 ACE MMP9 SERPINC1 SERPINE1
41 thrombophilia 29.9 F3 PLAT SERPINC1 SERPINE1 SERPINF2 VWF
42 respiratory failure 29.9 ACE CRP EDN1 F3 PIK3C2A
43 cerebrovascular disease 29.8 ACE CRP MMP9 PLAT SELP SERPINE1
44 arteriosclerosis 29.7 ACE CRP EDN1 F3 MMP9 SELP
45 disseminated intravascular coagulation 29.6 F3 MB PIK3C2A PLAT SERPINC1 SERPINE1
46 coronary artery anomaly 29.4 ACE ADRB1 CRP EDN1 MB NPPA
47 peripheral vascular disease 29.3 ACE CRP F3 PLAT SELP SERPINC1
48 stroke, ischemic 29.3 ACE CRP F3 PLAT SELP SERPINC1
49 intermediate coronary syndrome 29.1 ACE CRP F3 MB PIK3C2A PLAT
50 myocardial infarction 29.1 ACE ADRB1 CKB CRP EDN1 F3

Comorbidity relations with Acute Myocardial Infarction via Phenotypic Disease Network (PDN): (show all 22)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Aortic Valve Disease 1
Cardiac Arrest Chronic Kidney Failure
Chronic Myocardial Ischemia Decubitus Ulcer
Deficiency Anemia Familial Atrial Fibrillation
Generalized Atherosclerosis Heart Disease
Hypertension, Essential Intermediate Coronary Syndrome
Ischemic Heart Disease Kidney Disease
Mitral Valve Disease Peripheral Vascular Disease
Protein-Energy Malnutrition Respiratory Failure
Schizophreniform Disorder Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Acute Myocardial Infarction:



Diseases related to Acute Myocardial Infarction

Symptoms & Phenotypes for Acute Myocardial Infarction

UMLS symptoms related to Acute Myocardial Infarction:


chest pain, angina pectoris

MGI Mouse Phenotypes related to Acute Myocardial Infarction:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.36 TNNI3 PLAT TNNT2 SELP VWF SERPINC1
2 homeostasis/metabolism MP:0005376 10.25 SERPINF2 PLAT TNNT2 SELP VWF SERPINC1
3 growth/size/body region MP:0005378 10.18 SERPINE1 PIK3C2A PLAT TNNT2 SELP EDN1
4 mortality/aging MP:0010768 10.13 TNNI3 PLAT TNNT2 SELP VWF SERPINC1
5 hematopoietic system MP:0005397 10.11 SERPINE1 PLAT VWF SELP SERPINC1 NPPA
6 muscle MP:0005369 9.85 TNNI3 PLAT TNNT2 NPPA F3 FABP3
7 renal/urinary system MP:0005367 9.56 SELP SERPINC1 SERPINE1 NPPA PIK3C2A ACE
8 respiratory system MP:0005388 9.17 SERPINE1 TNNI3 PLAT SELP F3 MB

Drugs & Therapeutics for Acute Myocardial Infarction

Drugs for Acute Myocardial Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 486)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pravastatin Approved Phase 4 81093-37-0 54687
2
Abciximab Approved Phase 4,Phase 3,Phase 2 143653-53-6
3
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
4
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 22916-47-8 4189
5
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 46835353 6436030 5284616
6
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-78-2 2244
7
Clopidogrel Approved Phase 4,Phase 3,Phase 2 120202-66-6, 113665-84-2 60606
8
Thrombin Approved, Investigational Phase 4
9
Bivalirudin Approved, Investigational Phase 4,Phase 3 128270-60-0 16129704
10
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 46507594 772
11
Tenecteplase Approved Phase 4,Phase 3,Phase 2 191588-94-0
12
Tirofiban Approved Phase 4,Phase 3 144494-65-5 60947
13
Colchicine Approved Phase 4,Phase 3,Phase 2 64-86-8 2833 6167
14
Ticagrelor Approved Phase 4,Phase 3,Phase 2 274693-27-5 9871419
15
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
16
Nicorandil Approved, Investigational Phase 4,Phase 3 65141-46-0 47528
17
Desflurane Approved Phase 4 57041-67-5 42113
18
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
19
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
20
Insulin Glargine Approved Phase 4,Phase 3 160337-95-1
21
Metformin Approved Phase 4,Phase 2,Phase 3 657-24-9 4091 14219
22
Zinc Approved, Investigational Phase 4,Phase 3,Phase 1 7440-66-6 32051 23994
23
Menthol Approved Phase 4,Phase 2,Phase 3 2216-51-5 16666
24
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
25
Valsartan Approved, Investigational Phase 4,Phase 3 137862-53-4 60846
26
Lenograstim Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 135968-09-1
27
Paclitaxel Approved, Vet_approved Phase 4,Phase 2,Phase 3 33069-62-4 36314
28
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
29
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2 58-61-7 60961
30
Rivaroxaban Approved Phase 4 366789-02-8
31
Amlodipine Approved Phase 4,Phase 3 88150-42-9 2162
32
Bezafibrate Approved, Investigational Phase 4 41859-67-0 39042
33
Streptokinase Approved, Investigational Phase 4,Phase 3 9002-01-1
34
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3 1994-09-7, 94-09-7 2337
35
Diltiazem Approved, Investigational Phase 4 42399-41-7 39186
36
Nitroglycerin Approved, Investigational Phase 4,Phase 3 55-63-0 4510
37
Verapamil Approved Phase 4 52-53-9 2520
38
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
39
Metoprolol Approved, Investigational Phase 4,Phase 3,Phase 1 51384-51-1, 37350-58-6 4171
40
Antipyrine Approved, Investigational Phase 4 60-80-0 2206
41
Aminophylline Approved Phase 4 317-34-0 9433
42
Ezetimibe Approved Phase 4 163222-33-1 150311
43
Insulin Lispro Approved Phase 4 133107-64-9
44
Dalteparin Approved Phase 4,Phase 3 9005-49-6
45
Reteplase Approved, Investigational Phase 4,Phase 3 133652-38-7 65820
46
Eplerenone Approved Phase 4,Phase 2 107724-20-9 443872 150310
47
Spironolactone Approved Phase 4,Phase 3 1952-01-7, 52-01-7 5833
48
Morphine Approved, Investigational Phase 4,Phase 3 57-27-2 5288826
49
Esomeprazole Approved, Investigational Phase 4 161796-78-7, 119141-88-7 9579578 4594
50
Famotidine Approved Phase 4 76824-35-6 3325

Interventional clinical trials:

(show top 50) (show all 1000)

# Name Status NCT ID Phase Drugs
1 Efficacy of Thrombosuction in Primary Percutaneous Coronary Intervention of Acute Myocardial Infarction Unknown status NCT01156662 Phase 4
2 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4 Pravastatin
3 Sirolimus Eluting Stenting in Acute Myocardial Infarction Unknown status NCT00288210 Phase 4
4 Anti-Restenosis After AMI by Erythropoietin Unknown status NCT00423020 Phase 4 Erythropoietin
5 IRIS : Use of Implantable Defibrillator in High-Risk Patients Early After Acute Myocardial Infarction Unknown status NCT00157768 Phase 4
6 Microvascular Reperfusion Utilizing Sonothrombolysis in Acute Myocardial Infarction (MRUSMI TRIAL) Unknown status NCT02170103 Phase 4 Microbubbles
7 Comparison of Primary PCI vs. Post-thrombolysis PCI as Reperfusion Strategies in STEMI Unknown status NCT02268669 Phase 4
8 Treating Acute MI Patients With Aggrastat on Their Way to Hospital Unknown status NCT00300833 Phase 4 Tirofiban
9 N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure Unknown status NCT00692718 Phase 4 Epadel, Eicosapentaenoic acid
10 Post-MI PET Scan Imaging of Inflammation Unknown status NCT02281305 Phase 4 Colchicine
11 Colchicine in ST-elevation Myocardial Infarction Unknown status NCT01936285 Phase 4 Colchicine 2 mg loading dose; 0.5 mg bid for 5 days;Placebo
12 Dissecting the Role of Distal Embolization of Athero-thrombotic Material in Primary PCI: the ThrombOticBurden and mIcrovAscularobStruction (TOBIAS) Study. Unknown status NCT01914055 Phase 4
13 Multicentre 2x2 Factorial Randomised Study Comparing Tirofiban Versus Abciximab and SES Versus BMS in AMI Unknown status NCT00229515 Phase 4
14 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4 Ticagrelor;Clopidogrel
15 Vitamin D and Inflammatory Cytokine Levels After Acute Myocardial Infraction (MI) Unknown status NCT01115842 Phase 4 Vitamin D
16 Effect of Nicorandil for the Patients of Acute ST Segment Elevation Myocardial Infarction Unknown status NCT02435797 Phase 4 Nicorandil;normal saline
17 Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome Unknown status NCT02446730 Phase 4 Prasugel;Clopidogrel
18 Clinical Performance of CRE8 Drug Eluting Stent in All Comer Population Unknown status NCT01556126 Phase 4
19 Efficacy Study of Combined Prasugrel and Bivalirudin Versus Clopidogrel and Heparin in Myocardial Infarction Unknown status NCT00976092 Phase 4 Prasugrel;Bivalirudin;Clopidogrel;Heparin
20 Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab Unknown status NCT01383785 Phase 4
21 Desflurane-induced Myocardial Protection Unknown status NCT02019797 Phase 4 Desflurane
22 Ticagrelor and Clopidogrel on Reperfusion in Patients With AMI Unknown status NCT02233790 Phase 4 Ticagrelor;Clopidogrel
23 Can Insulin Glargine Improve Myocardial Function in Patients With T2D and Coronary Artery Disease (CAD) Unknown status NCT01035528 Phase 4 insulin glargine;metformin
24 A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction Unknown status NCT01942070 Phase 4
25 CT Coronary Angiogram Versus Traditional Care in Emergency Department Assessment of Potential ACS Unknown status NCT00933400 Phase 4
26 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4 valsartan
27 The Pacing vs No Pacing Study - PNP Study Unknown status NCT02498639 Phase 4
28 Bezafibrate for Hyperfibrinogenemia in Acute Myocardial Infarction Completed NCT02291796 Phase 4 Bezafibrate
29 Effect of Complementary Intracoronary Streptokinase Administration Immediately After Primary Percutaneous Coronary Intervention on Microvascular Perfusion and Late Term Infarct Size in Patients With Acute Myocardial Infarction Completed NCT00302419 Phase 4 intracoronary infusion,
30 GPIIbIIIa Inhibitors in the RESCUe and RESURCOR Networks at the Acute Myocardial Infarction Completed NCT00538317 Phase 4 tirofiban;tirofiban
31 REsistance to Aspirin and Clopidogrel in acuTe Myocardial Infarction Completed NCT01381185 Phase 4 Aspirin 200mg qd, Clopidogrel 2x75mg qd
32 Tight Glycemic Control Increases Cardiac Stem Cells During Acute Myocardial Infarction Completed NCT00863629 Phase 4 Insulin
33 The Effect of Erythropoietin at the Time of Reperfusion in Acute Myocardial Infarction Completed NCT00882466 Phase 4 human recombinant erythropoietin
34 BivaliRudin in Acute Myocardial Infarction vs Glycoprotein IIb/IIIa and Heparin :a Randomised Controlled Trial. Completed NCT01696110 Phase 4 Bivalirudin;heparin;heparin plus tirofiban
35 Southwest German Interventional Study in Acute Myocardial Infarction III Completed NCT01124890 Phase 4
36 Effects of Different Vasodilators on Coronary No-reflow During primAry percuTaneous Coronary intErvention in Patients With Acute Myocardial Infarction Completed NCT00712894 Phase 4 Diltiazem;Verapamil;Nitroglycerin
37 Safety and Efficacy of Three Different Loading Doses of Clopidogrel, in Patients With Acute Myocardial Infarction Completed NCT00882739 Phase 4 Clopidogrel 300 mg;Clopidogrel 600 mg;Clopidogrel 900 mg
38 Effect of Adjunctive Intracoronary Streptokinase on Late Term Left Ventricular Infarct Size and Volumes in Patients With Acute Myocardial Infarction Completed NCT00627809 Phase 4 Streptokinase
39 Effects of Atorvastatin 10 mg Versus 40 mg in Eight Months Follow-up Coronary Flow Reserve and Bone Marrow Stem Cell Mobilization in Patients With Acute Myocardial Infarction Completed NCT00536887 Phase 4 atorvastatin
40 Comparison Between Iso-Osmolar and Ipo-Osmolar Contrast Agents in Patients With Acute Myocardial Infarction (AMI) Undergoing Primary Percutaneous Coronary Intervention (PCI) Completed NCT00827788 Phase 4 Iodixanol;Iopromide
41 Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial Infarction Completed NCT02808767 Phase 4 Prasugrel;Ticagrelor
42 The Effects of Facilitated Percutaeous Coronary Intervention in Acute Myocardial Infarction Completed NCT00611169 Phase 4 tirofiban
43 Intensive Insulin Therapy in Non-diabetic Patients With Acute Myocardial Infarction and Hyperglycaemia Completed NCT00362778 Phase 4 Insulin
44 Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction (AMI) Patients According to CYP2C19 Polymorphism Completed NCT00915733 Phase 4 cilostazol;clopidogrel (Plavix);aspirin (Acetylsalicylic acid)
45 Efficacy of Everolimus-Eluting Versus Zotarolimus-Eluting Sten for Coronary Lesions in Acute Myocardial Infarction Completed NCT01347554 Phase 4
46 Effects of Early Statin Treatment After Acute Myocardial Infarction (AMI) in Japanese Patients Completed NCT00128024 Phase 4 lipid-lowering treatment
47 Effect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion. The METOCARD-CNIC Trial. Completed NCT01311700 Phase 4 Injectable (i.v.) metoprolol tartrate (up to 15 mg).
48 Efficacy of Early Administration of Clotinab in Acute Myocardial Infarction Completed NCT00841438 Phase 4 Clotinab;Clotinab
49 Levosimendan in Acute Heart Failure Following Acute Myocardial Infarction. Completed NCT00324766 Phase 4 levosimendan;placebo,
50 Pilot Study of Edaravone to Treat Acute Myocardial Infarction Completed NCT00265239 Phase 4 edaravone

Search NIH Clinical Center for Acute Myocardial Infarction

Genetic Tests for Acute Myocardial Infarction

Anatomical Context for Acute Myocardial Infarction

MalaCards organs/tissues related to Acute Myocardial Infarction:

38
Heart, Bone, Bone Marrow, Endothelial, Brain, Testes, Monocytes

Publications for Acute Myocardial Infarction

Articles related to Acute Myocardial Infarction:

(show top 50) (show all 2887)
# Title Authors Year
1
Effect of a Quality Improvement Intervention on Clinical Outcomes in Patients in India With Acute Myocardial Infarction: The ACS QUIK Randomized Clinical Trial. ( 29450524 )
2018
2
Gambogic acid exerts cardioprotective effects in a rat model of acute myocardial infarction through inhibition of inflammation, iNOS and NF-I_B/p38 pathway. ( 29434760 )
2018
3
rLj-RGD3, a novel recombinant toxin protein from Lampetra japonica, prevents coronary thrombosis-induced acute myocardial infarction by inhibiting platelet functions in rats. ( 29407168 )
2018
4
Doppler Versus Thermodilution-Derived Coronary Microvascular Resistance to Predict Coronary Microvascular Dysfunction in Patients With Acute Myocardial Infarction or Stable Angina Pectoris. ( 29132649 )
2018
5
Buckberg's blood cardioplegia for protection of adult and senile myocardium in a rat in vitro model of acute myocardial infarction. ( 29432894 )
2018
6
Accelerated idioventricular rhythm degenerating into bidirectional ventricular tachycardia following acute myocardial infarction. ( 29429799 )
2018
7
Rapid increases in nitrogen oxides are associated with acute myocardial infarction: A case-crossover study. ( 29446990 )
2018
8
Revision: prognostic impact of baseline glucose levels in acute myocardial infarction complicated by cardiogenic shock-a substudy of the IABP-SHOCK II-trial. ( 29423774 )
2018
9
Effects of smoke-free air law on acute myocardial infarction hospitalization in Indianapolis and Marion County, Indiana. ( 29426315 )
2018
10
Circulating miR-379 as a potential novel biomarker for diagnosis of acute myocardial infarction. ( 29424915 )
2018
11
Correction to: Air quality and acute myocardial infarction in adults during the 2016 Hangzhou G20 summit. ( 29450769 )
2018
12
Persistent Inflammation, Stem Cell-Induced Systemic Anti-Inflammatory Effects, and Need for Repeated Stem Cell Injections: Critical Concepts Influencing Optimal Stem Cell Strategies for Treating Acute Myocardial Infarction and Heart Failure. ( 29440037 )
2018
13
Fried food intake and risk of nonfatal acute myocardial infarction in the Costa Rica Heart Study. ( 29447246 )
2018
14
Acute myocardial infarction in a 25-year-old woman with sitosterolemia. ( 29174072 )
2018
15
Long-term Prognosis and Clinical Characteristics of Patients with Newly Diagnosed Diabetes Mellitus Detected after First Acute Myocardial Infarction: from KAMIR-NIH Registry. ( 29441746 )
2018
16
Clinical Significance of Newly Diagnosed Diabetes Mellitus in the Era of DES for Acute Myocardial Infarction. ( 29441749 )
2018
17
A foreign older diabetic woman with an acute myocardial infarction: when cognitive biases in clinical decision-making become especially important. ( 29437739 )
2018
18
Acute Myocardial Infarction in a Patient with Isolated Dextrocardia. ( 29431312 )
2018
19
Impact of generalized anxiety disorder (GAD) on prehospital delay of acute myocardial infarction patients. Findings from the multicenter MEDEA study. ( 29383439 )
2018
20
Ac-SDKP decreases mortality and cardiac rupture after acute myocardial infarction. ( 29364896 )
2018
21
MicroRNAs in acute myocardial infarction: Evident value as novel biomarkers? ( 29424735 )
2018
22
Blood cardioplegia for cardiac surgery in acute myocardial infarction: rat experiments with two widely used solutions. ( 29452370 )
2018
23
Acute stress disorder and C-reactive protein in patients with acute myocardial infarction. ( 29243511 )
2018
24
Outcome after revascularisation of acute myocardial infarction with cardiogenic shock on extracorporeal life support. ( 29400656 )
2018
25
Chart validation of inpatient ICD-9-CM administrative diagnosis codes for acute myocardial infarction (AMI) among intravenous immune globulin (IGIV) users in the Sentinel Distributed Database. ( 29446185 )
2018
26
Hyperuricemia is associated with short-term outcomes in elderly patients with acute myocardial infarction. ( 29411328 )
2018
27
Complementary Diagnostic Value of Heart Type Fatty Acid-binding Protein in Early Detection of Acute Myocardial Infarction. ( 29432376 )
2018
28
Cardiac rupture during acute myocardial infarction diagnosed clinically. ( 29394186 )
2018
29
Integrating invasive hemodynamic parameters into risk stratification of acute myocardial infarction and cardiogenic shock. ( 28891162 )
2017
30
Inferior Wall Acute Myocardial Infarction: Not as Preload Dependent as Once Thought? ( 28089058 )
2017
31
Prognostic value of total triiodothyronine and free thyroxine levels for the heart failure in patients with acute myocardial infarction. ( 28073241 )
2017
32
Correlation between electrocardiographic changes and coronary findings in patients with acute myocardial infarction and single-vessel disease. ( 28936441 )
2017
33
Incidence of atrial fibrillation detected by continuous rhythm monitoring after acute myocardial infarction in patients with preserved left ventricular ejection fraction: results of the ARREST study. ( 28069838 )
2017
34
Long-term outcome and risk prediction in patients suffering acute myocardial infarction complicated by post-infarction cardiac rupture. ( 27847155 )
2017
35
Cardiac I+VI^3 integrin expression following acute myocardial infarction in humans. ( 27927700 )
2017
36
Circulating Long Noncoding RNA HOTAIR is an Essential Mediator of Acute Myocardial Infarction. ( 29258067 )
2017
37
Gelatinases A and B and Antioxidant Enzyme Activity in the Early Phase of Acute Myocardial Infarction. ( 28374671 )
2017
38
In-hospital outcomes of acute myocardial infarction with cardiogenic shock caused by right coronary artery occlusion vs. left coronary artery occlusion. ( 28918455 )
2017
39
Mobilized Muse Cells After Acute Myocardial Infarction Predict Cardiac Function and Remodeling in the Chronic Phase. ( 28931784 )
2017
40
Predictors of Acute Myocardial Infarction. ( 28925650 )
2017
41
ST-segment elevation acute myocardial infarction associated with hyperthyroidism: beware of coronary spasm! ( 28858949 )
2017
42
Identifying key genes associated with acute myocardial infarction. ( 29049183 )
2017
43
Functional genetic variants within the SIRT2 gene promoter in acute myocardial infarction. ( 28445509 )
2017
44
Direct Comparison of 2 Rule-Out Strategies for Acute Myocardial Infarction: 2-h Accelerated Diagnostic Protocol vs 2-h Algorithm. ( 28515106 )
2017
45
The prognostic value of shock index for the outcomes of acute myocardial infarction patients: A systematic review and meta-analysis. ( 28930837 )
2017
46
Extra-cellular expansion in the normal, non-infarcted myocardium is associated with worsening of regional myocardial function after acute myocardial infarction. ( 28946878 )
2017
47
Cardiac Cell Therapies for the Treatment of Acute Myocardial Infarction: A Meta-Analysis from Mouse Studies. ( 28535507 )
2017
48
Fibromuscular Dysplasia with Spontaneous Coronary Artery Disease Presenting as Acute Myocardial Infarction. ( 28652952 )
2017
49
Ellagic acid promotes ventricular remodeling after acute myocardial infarction by up-regulating miR-140-3p. ( 28922712 )
2017
50
Adherence Tradeoff to Multiple Preventive Therapies and All-Cause Mortality After Acute Myocardial Infarction. ( 28935030 )
2017

Variations for Acute Myocardial Infarction

Copy number variations for Acute Myocardial Infarction from CNVD:

7
# CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 210497 6 30400000 36600000 Amplification C4B Acute myocardial infarction

Expression for Acute Myocardial Infarction

LifeMap Discovery
Genes differentially expressed in tissues of Acute Myocardial Infarction patients vs. healthy controls: 35
# Gene Description Tissue Up/Dn Fold Change (log2) P value
1 EGR3 early growth response 3 Blood + 5.52 0.000
2 LOC286058 uncharacterized LOC286058 Blood + 4.73 0.000
3 CXCL8 chemokine (C-X-C motif) ligand 8 Blood + 3.51 0.004
4 LEP leptin Heart + 3.45 0.011
5 ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein Blood + 3.18 0.007
Search GEO for disease gene expression data for Acute Myocardial Infarction.

Pathways for Acute Myocardial Infarction

GO Terms for Acute Myocardial Infarction

Cellular components related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.93 ACE CRP EDN1 F3 MMP9 NPPA
2 extracellular exosome GO:0070062 9.77 ACE CKB CRP F3 FABP3 MB
3 extracellular matrix GO:0031012 9.73 F3 MMP9 NPPA PLAT SERPINE1 VWF
4 platelet alpha granule lumen GO:0031093 9.63 SERPINE1 SERPINF2 VWF
5 extracellular space GO:0005615 9.47 ACE CKB CRP EDN1 F3 FABP3
6 troponin complex GO:0005861 9.43 TNNI3 TNNT2
7 cardiac myofibril GO:0097512 9.4 TNNI3 TNNT2
8 Weibel-Palade body GO:0033093 9.37 EDN1 VWF
9 cardiac Troponin complex GO:1990584 9.32 TNNI3 TNNT2

Biological processes related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.73 F3 PLAT SERPINC1 VWF
2 response to hypoxia GO:0001666 9.62 EDN1 MB NPPA PLAT
3 response to muscle stretch GO:0035994 9.58 EDN1 NPPA
4 hemostasis GO:0007599 9.58 F3 SERPINC1 VWF
5 heart contraction GO:0060047 9.57 ACE TNNI3
6 negative regulation of blood coagulation GO:0030195 9.56 EDN1 SERPINE1
7 platelet degranulation GO:0002576 9.56 SELP SERPINE1 SERPINF2 VWF
8 regulation of blood vessel diameter GO:0097746 9.55 ACE NPPB
9 positive regulation of renal sodium excretion GO:0035815 9.54 EDN1 NPPB
10 positive regulation of urine volume GO:0035810 9.52 EDN1 NPPB
11 negative regulation of fibrinolysis GO:0051918 9.51 SERPINE1 SERPINF2
12 negative regulation of ATPase activity GO:0032780 9.49 TNNI3 TNNT2
13 receptor guanylyl cyclase signaling pathway GO:0007168 9.48 NPPA NPPB
14 body fluid secretion GO:0007589 9.46 EDN1 NPPB
15 negative regulation of plasminogen activation GO:0010757 9.37 SERPINE1 SERPINF2
16 fibrinolysis GO:0042730 9.33 PLAT SERPINE1 SERPINF2
17 regulation of blood vessel size GO:0050880 9.13 EDN1 NPPA NPPB
18 regulation of blood pressure GO:0008217 8.92 ACE EDN1 NPPA NPPB

Molecular functions related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.65 EDN1 NPPA NPPB PLAT SERPINE1
2 serine-type endopeptidase inhibitor activity GO:0004867 9.54 SERPINC1 SERPINE1 SERPINF2
3 hormone receptor binding GO:0051427 9.16 NPPA NPPB
4 protease binding GO:0002020 9.02 F3 SERPINC1 SERPINE1 SERPINF2 VWF
5 troponin C binding GO:0030172 8.96 TNNI3 TNNT2
6 protein binding GO:0005515 10.25 ADRB1 CKB CRP EDN1 F3 FABP3

Sources for Acute Myocardial Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
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43 MGI
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50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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