MCID: ACT075
MIFTS: 59

Acute Myocardial Infarction

Categories: Cardiovascular diseases, Genetic diseases

Aliases & Classifications for Acute Myocardial Infarction

MalaCards integrated aliases for Acute Myocardial Infarction:

Name: Acute Myocardial Infarction 38 12 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9408
ICD10 33 I21.3 I21
ICD9CM 35 410 410.9 410.90
NCIt 47 C35204
UMLS 69 C0155626

Summaries for Acute Myocardial Infarction

MalaCards based summary : Acute Myocardial Infarction is related to essential thrombocythemia and adenocarcinoma, and has symptoms including angina pectoris and chest pain. An important gene associated with Acute Myocardial Infarction is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and AGE-RAGE signaling pathway in diabetic complications. The drugs Pravastatin and Abciximab have been mentioned in the context of this disorder. Affiliated tissues include heart, bone and endothelial, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Acute Myocardial Infarction

Diseases in the Myocardial Infarction family:

Myocardial Infarction 2 Acute Myocardial Infarction
Posterior Myocardial Infarction Myocardial Infarction, Susceptibility to, 1

Diseases related to Acute Myocardial Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 402)
id Related Disease Score Top Affiliating Genes
1 essential thrombocythemia 31.0 F3 SERPINC1 VWF
2 adenocarcinoma 30.6 ACE MB PIK3C2A
3 angina pectoris 30.3 ACE CRP F3 PLAT SELP SERPINC1
4 ischemic heart disease 29.5 ACE CRP SELP SERPINC1 SERPINE1 TNNT2
5 pericarditis 28.7 ACE CRP EDN1 F3 MMP9 PLAT
6 myocardial infarction 27.6 ACE ADRB1 CKB CRP EDN1 F3
7 strictly posterior acute myocardial infarction 12.0
8 subendocardial infarction acute myocardial infarction 12.0
9 coronary artery disease, autosomal dominant, 1 11.2
10 coronary artery disease, autosomal dominant, 2 11.0
11 hyperlipoproteinemia, type iii 11.0
12 islet cell tumor 10.9 ACE CRP NPPB
13 global developmental delay-osteopenia-ectodermal defect syndrome 10.9 TNNI3 TNNT2
14 synovial chondromatosis 10.9 ACE NPPA NPPB
15 atrial septal defect 7, with or without av conduction defects 10.9 ACE NPPA
16 iron metabolism disease 10.9 ACE CRP SELP
17 suppurative otitis media 10.9 ACE NPPA NPPB
18 primary hyperoxaluria 10.9 ACE SERPINC1
19 colon leiomyoma 10.9 ACE PIK3C2A
20 ciliary discoordination, due to random ciliary orientation 10.9 CRP EDN1 NPPB
21 hypodontia of incisors and premolars 10.9 ACE NPPA
22 prostate malignant phyllodes tumor 10.9 ACE CRP NPPB
23 uterine inflammatory disease 10.9 EDN1 SERPINE1
24 coronary thrombosis 10.9
25 conjunctival disease 10.8 ACE PLAT SERPINC1
26 broad ligament malignant neoplasm 10.8 ACE EDN1 NPPB
27 chylocele of tunica vaginalis 10.8 ACE EDN1 NPPA
28 visual snow syndrome 10.8 MB PIK3C2A
29 myopia 10.8 ACE EDN1 NPPA
30 arteriovenous malformation 10.8 PIK3C2A TNNI3
31 lymphadenitis 10.8 ACE EDN1 NPPA
32 malignant hypertension 10.8 MB PLAT TNNI3
33 lateral myocardial infarction 10.8 NPPB PIK3C2A PLAT
34 dementia pugilistica 10.8 NPPB PIK3C2A PLAT
35 pancreas lymphoma 10.8 CRP NPPB TNNT2
36 focal dystonia 10.8 ACE CRP SELP
37 arcus senilis 10.8 CRP F3 SERPINE1
38 microphthalmia, isolated, with coloboma 7 10.8 ACE MB PIK3C2A
39 congenital syphilis 10.8 CRP F3 SERPINC1
40 venezuelan hemorrhagic fever 10.8 PLAT SERPINC1 SERPINE1
41 aryepiglottic fold cancer 10.8 F3 PLAT SERPINC1
42 al gazali sabrinathan nair syndrome 10.8 TNNT2 VWF
43 sagittal sinus thrombosis 10.8 F3 SERPINC1
44 oppositional defiant disorder 10.8 PLAT SELP SERPINE1
45 fragile x syndrome type 2 10.8 F3 SERPINC1
46 hereditary amyloidosis 10.7 F3 SELP SERPINC1
47 inferolateral myocardial infarct 10.7 MB SERPINC1 SERPINE1
48 elizabethkingia anophelis infection 10.7 EDN1 PLAT VWF
49 calcinosis 10.7 ACE CRP EDN1
50 laryngostenosis 10.7 ACE MMP9 NPPB

Comorbidity relations with Acute Myocardial Infarction via Phenotypic Disease Network (PDN): (show all 22)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Cardiac Arrest
Chronic Kidney Failure Chronic Myocardial Ischemia
Decubitus Ulcer Deficiency Anemia
Familial Atrial Fibrillation Generalized Atherosclerosis
Heart Disease Hypertension, Essential
Intermediate Coronary Syndrome Ischemic Heart Disease
Kidney Disease Left Ventricular Outflow Tract Obstruction
Mitral Valve Disease Peripheral Vascular Disease
Protein-Energy Malnutrition Respiratory Failure
Schizophreniform Disorder Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Acute Myocardial Infarction:



Diseases related to Acute Myocardial Infarction

Symptoms & Phenotypes for Acute Myocardial Infarction

UMLS symptoms related to Acute Myocardial Infarction:


angina pectoris, chest pain

MGI Mouse Phenotypes related to Acute Myocardial Infarction:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.36 TNNI3 TNNT2 VWF ACE ADRB1 CRP
2 homeostasis/metabolism MP:0005376 10.25 ACE ADRB1 CRP EDN1 F3 FABP3
3 growth/size/body region MP:0005378 10.18 ACE ADRB1 CKB EDN1 F3 MB
4 mortality/aging MP:0010768 10.13 ACE ADRB1 EDN1 F3 FABP3 MB
5 hematopoietic system MP:0005397 10.11 ACE F3 MB MMP9 NPPA PIK3C2A
6 muscle MP:0005369 9.85 TNNT2 ADRB1 EDN1 F3 FABP3 MB
7 renal/urinary system MP:0005367 9.56 SERPINC1 SERPINE1 ACE EDN1 MMP9 NPPA
8 respiratory system MP:0005388 9.17 SELP SERPINE1 TNNI3 F3 MB MMP9

Drugs & Therapeutics for Acute Myocardial Infarction

Drugs for Acute Myocardial Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 571)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pravastatin Approved Phase 4 81093-37-0 54687
2
Abciximab Approved Phase 4,Phase 3,Phase 2 143653-53-6
3
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
4
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 22916-47-8 4189
5
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
6
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-78-2 2244
7
Thrombin Approved Phase 4,Phase 3
8
Bivalirudin Approved, Investigational Phase 4,Phase 3 128270-60-0 16129704
9
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 772 46507594
10
Tenecteplase Approved Phase 4,Phase 3,Phase 2 191588-94-0
11
Tirofiban Approved Phase 4,Phase 3,Phase 2 144494-65-5 60947
12
Colchicine Approved Phase 4,Phase 3,Phase 2 64-86-8 6167 2833
13
Ticagrelor Approved Phase 4,Phase 3,Phase 2 274693-27-5 9871419
14
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
15
Nicorandil Approved Phase 4,Phase 3 65141-46-0 47528
16
Desflurane Approved Phase 4 57041-67-5 42113
17
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
18
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
19
Insulin Glargine Approved Phase 4,Phase 3 160337-95-1
20
Metformin Approved Phase 4,Phase 2,Phase 3 657-24-9 14219 4091
21
Zinc Approved Phase 4,Phase 3,Phase 1 7440-66-6 32051 23994
22
Menthol Approved Phase 4,Phase 2,Phase 3 2216-51-5 16666
23
Etanercept Approved, Investigational Phase 4 185243-69-0
24
Valsartan Approved, Investigational Phase 4,Phase 3 137862-53-4 60846
25
Citalopram Approved Phase 4,Phase 2 59729-33-8 2771
26
Ramipril Approved Phase 4,Phase 2,Phase 3 87333-19-5 5362129
27
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
28
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3 73590-58-6 4594
29
Pantoprazole Approved Phase 4,Phase 3 102625-70-7 4679
30
Chromium Approved Phase 4 7440-47-3 27668
31
Lenograstim Approved Phase 4,Phase 2,Phase 3,Phase 1 135968-09-1
32
Morphine Approved, Investigational Phase 4,Phase 3 57-27-2 5288826
33
Paclitaxel Approved, Vet_approved Phase 4,Phase 2,Phase 3 33069-62-4 36314
34
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
35
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2 58-61-7 60961
36
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2 188627-80-7 123610
37
Exenatide Approved, Investigational Phase 4,Phase 3 141758-74-9 15991534
38
Rivaroxaban Approved Phase 4,Phase 3,Phase 2 366789-02-8
39
Amlodipine Approved Phase 4,Phase 3 88150-42-9 2162
40
Warfarin Approved Phase 4,Phase 3 81-81-2 6691 54678486
41
Nitric Oxide Approved Phase 4,Phase 2,Phase 3 10102-43-9 145068
42
Bezafibrate Approved Phase 4 41859-67-0 39042
43
Streptokinase Approved Phase 4,Phase 3 9002-01-1
44
Benzocaine Approved Phase 4,Phase 2,Phase 3 1994-09-7, 94-09-7 2337
45
Diltiazem Approved Phase 4 42399-41-7 39186
46
Nitroglycerin Approved, Investigational Phase 4,Phase 3 55-63-0 4510
47
Verapamil Approved Phase 4 52-53-9 2520
48
Cilostazol Approved Phase 4 73963-72-1 2754
49
Antipyrine Approved Phase 4 60-80-0 2206
50
Aminophylline Approved Phase 4 317-34-0 9433

Interventional clinical trials:

(show top 50) (show all 1504)

id Name Status NCT ID Phase Drugs
1 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4 Pravastatin
2 Sirolimus Eluting Stenting in Acute Myocardial Infarction Unknown status NCT00288210 Phase 4
3 Efficacy of Thrombosuction in Primary Percutaneous Coronary Intervention of Acute Myocardial Infarction Unknown status NCT01156662 Phase 4
4 Anti-Restenosis After AMI by Erythropoietin Unknown status NCT00423020 Phase 4 Erythropoietin
5 IRIS : Use of Implantable Defibrillator in High-Risk Patients Early After Acute Myocardial Infarction Unknown status NCT00157768 Phase 4
6 Reverse the HYpoTHyroid Status in Acute Myocardial InfarCtion (RHYTHMIC) Unknown status NCT02512978 Phase 4 Levothyroxine
7 Microvascular Reperfusion Utilizing Sonothrombolysis in Acute Myocardial Infarction (MRUSMI TRIAL) Unknown status NCT02170103 Phase 4 Microbubbles
8 Comparison of Primary PCI vs. Post-thrombolysis PCI as Reperfusion Strategies in STEMI Unknown status NCT02268669 Phase 4
9 Treating Acute MI Patients With Aggrastat on Their Way to Hospital Unknown status NCT00300833 Phase 4 Tirofiban
10 N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure Unknown status NCT00692718 Phase 4 Epadel, Eicosapentaenoic acid
11 Colchicine in ST-elevation Myocardial Infarction Unknown status NCT01936285 Phase 4 Colchicine 2 mg loading dose; 0.5 mg bid for 5 days;Placebo
12 Multicentre 2x2 Factorial Randomised Study Comparing Tirofiban Versus Abciximab and SES Versus BMS in AMI Unknown status NCT00229515 Phase 4
13 Dissecting the Role of Distal Embolization of Athero-thrombotic Material in Primary PCI: the ThrombOticBurden and mIcrovAscularobStruction (TOBIAS) Study. Unknown status NCT01914055 Phase 4
14 Post-MI PET Scan Imaging of Inflammation Unknown status NCT02281305 Phase 4 Colchicine
15 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4 Ticagrelor;Clopidogrel
16 Effect of Nicorandil for the Patients of Acute ST Segment Elevation Myocardial Infarction Unknown status NCT02435797 Phase 4 Nicorandil;normal saline
17 Efficacy Study of Combined Prasugrel and Bivalirudin Versus Clopidogrel and Heparin in Myocardial Infarction Unknown status NCT00976092 Phase 4 Prasugrel;Bivalirudin;Clopidogrel;Heparin
18 Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome Unknown status NCT02446730 Phase 4 Prasugel;Clopidogrel
19 Vitamin D and Inflammatory Cytokine Levels After Acute Myocardial Infraction (MI) Unknown status NCT01115842 Phase 4 Vitamin D
20 Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab Unknown status NCT01383785 Phase 4
21 Ticagrelor and Clopidogrel on Reperfusion in Patients With AMI Unknown status NCT02233790 Phase 4 Ticagrelor;Clopidogrel
22 Desflurane-induced Myocardial Protection Unknown status NCT02019797 Phase 4 Desflurane
23 Can Insulin Glargine Improve Myocardial Function in Patients With T2D and Coronary Artery Disease (CAD) Unknown status NCT01035528 Phase 4 insulin glargine;metformin
24 CT Coronary Angiogram Versus Traditional Care in Emergency Department Assessment of Potential ACS Unknown status NCT00933400 Phase 4
25 A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction Unknown status NCT01942070 Phase 4
26 Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction Unknown status NCT01372930 Phase 4 Etanercept;saline
27 Thrombus Aspiration During Percutaneous Coronary Intervention in Acute Non-ST-elevation Myocardial Infarction Study Unknown status NCT01013038 Phase 4
28 Effects of Intensive Statin Treatment on Left Ventricular Function Unknown status NCT01936103 Phase 4 standard group;intensive group
29 Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome Unknown status NCT01372839 Phase 4 Atorvastatin;Statin
30 The Pacing vs No Pacing Study - PNP Study Unknown status NCT02498639 Phase 4
31 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4 valsartan
32 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4 Escitalopram
33 Clopidogrel Reloading in Patients With NSTEACS Undergoing Percutaneous Coronary Intervention on Chronic Clopidogrel Therapy Unknown status NCT01572129 Phase 4 Clopidogrel;Placebo
34 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4 Ticagrelor loading;Prasugrel loading
35 Telmisartan Versus Ramipril After Acute Coronary Syndrome Unknown status NCT00702936 Phase 4 TELMISARTAN;RAMIPRIL
36 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4 Ivabradine;Placebo
37 Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN) Unknown status NCT01735227 Phase 4 omeprazole;Pantoprazole
38 Comparing Ticagrelor and Clopidogrel Pharmacodynamics After Thrombolysis Unknown status NCT02048085 Phase 4 Ticagrelor;Clopidogrel
39 Efficacy of Ticagrelor vs Clopidogrel in High-risk NSTE-ACS Patients Undergoing Early PCI Unknown status NCT02201667 Phase 4 Ticagrelor;clopidogrel;Aspirin
40 Optimizing Infarct Size by Transforming Emergent Stenting Into an Elective Procedure Study Unknown status NCT01462188 Phase 4
41 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4 ticagrelor loading;Clopidogrel loading
42 Customized Choice of Oral P2Y12 Receptor Blocker Unknown status NCT01477775 Phase 4 Oral P2Y12 receptor blocker;Customized choice for the oral P2Y12 receptor blocker
43 Effect of Conditioning on Myocardial Damage in STEMI Unknown status NCT02158468 Phase 4
44 Colchicine for Acute Coronary Syndromes Unknown status NCT01906749 Phase 4 Colchicine;Placebo
45 Comparative Phase IV Study: Efficacy And Safety of TiTAN2 Versus COBALT-CHROME Stents- EVIDENCEII Unknown status NCT01918150 Phase 4
46 Intensive Lipid Lowering Treatment in Non-ST-elevation Acute Coronary Syndrome (NSTE-ACS) Patients Unknown status NCT01040936 Phase 4 Atorvastatin;Atorvastatin
47 Randomized Trial of Creatine-kinase Leak After Rosuvastatin At the Time of Percutaneous Coronary Intervention Unknown status NCT01968577 Phase 4 Rosuvastatin
48 Diagnosis and Treatment of ACS in the ED: The Impact of Rapid Bedside cTnI Testing on Outcomes Unknown status NCT00222352 Phase 4
49 Sleep Disordered Breathing in Transient Ischemic Attack (TIA)/Ischemic Stroke and Continuous Positive Airway Pressure (CPAP) Treatment Efficacy Unknown status NCT01097967 Phase 4
50 Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing Unknown status NCT00698607 Phase 4 6-month clopidogrel therapy;12-month clopidogrel therapy

Search NIH Clinical Center for Acute Myocardial Infarction

Genetic Tests for Acute Myocardial Infarction

Anatomical Context for Acute Myocardial Infarction

MalaCards organs/tissues related to Acute Myocardial Infarction:

39
Heart, Bone, Endothelial, Bone Marrow, Testes, Brain, Kidney

Publications for Acute Myocardial Infarction

Articles related to Acute Myocardial Infarction:

(show top 50) (show all 2843)
id Title Authors Year
1
Long-term outcome and risk prediction in patients suffering acute myocardial infarction complicated by post-infarction cardiac rupture. ( 27847155 )
2017
2
Coronary Aneurysm Formation After Bioresorbable Vascular Scaffold Implantation Resulting in Acute Myocardial Infarction. ( 28512285 )
2017
3
Fibromuscular Dysplasia with Spontaneous Coronary Artery Disease Presenting as Acute Myocardial Infarction. ( 28652952 )
2017
4
Response by Heydari et al to Letter Regarding Article, "Effect of Omega-3 Acid Ethyl Esters on Left Ventricular Remodeling After Acute Myocardial Infarction: The OMEGA-REMODEL Randomized Clinical Trial". ( 28069718 )
2017
5
Cardiac remodeling following reperfused acute myocardial infarction is linked to the concomitant evolution of vascular function as assessed by cardiovascular magnetic resonance. ( 28063459 )
2017
6
Trimethylamine N-oxide and Risk Stratification after Acute Myocardial Infarction. ( 28062632 )
2017
7
Acute myocardial infarction in patients of nephrotic syndrome: a case series. ( 28868077 )
2017
8
Correlation between electrocardiographic changes and coronary findings in patients with acute myocardial infarction and single-vessel disease. ( 28936441 )
2017
9
Beta-blockers reduced the risk of cardiac rupture in patients with acute myocardial infarction: A meta-analysis of randomized control trials. ( 28109576 )
2017
10
Prognostic impact of unrecognized myocardial scar in the non-culprit territories by cardiac magnetic resonance imaging in patients with acute myocardial infarction. ( 28950314 )
2017
11
Circulating MicroRNA-145 is Associated with Acute Myocardial Infarction and Heart Failure. ( 28051023 )
2017
12
Expression pattern of genome-scale long noncoding RNA following acute myocardial infarction in Chinese Uyghur patients. ( 28418905 )
2017
13
Cardiac Troponin T: Smaller Molecules in Patients with End-Stage Renal Disease than after Onset of Acute Myocardial Infarction. ( 28073901 )
2017
14
Incidence of atrial fibrillation detected by continuous rhythm monitoring after acute myocardial infarction in patients with preserved left ventricular ejection fraction: results of the ARREST study. ( 28069838 )
2017
15
Integrating invasive hemodynamic parameters into risk stratification of acute myocardial infarction and cardiogenic shock. ( 28891162 )
2017
16
Letter by Koh Regarding Article, "Effect of Omega-3 Acid Ethyl Esters on Left Ventricular Remodeling After Acute Myocardial Infarction: The OMEGA-REMODEL Randomized Clinical Trial". ( 28069716 )
2017
17
Gelatinases A and B and Antioxidant Enzyme Activity in the Early Phase of Acute Myocardial Infarction. ( 28374671 )
2017
18
History of erectile dysfunction as a predictor of poor physical performance after an acute myocardial infarction. ( 28067536 )
2017
19
The potential of optimizing prehospital triage of patients with suspected acute myocardial infarction using high-sensitivity cardiac troponin T and copeptin. ( 27903076 )
2017
20
The relationship between apnoea hypopnoea index and Gensini score in patients with acute myocardial infarction undergoing emergency primary percutaneous coronary intervention. ( 28932553 )
2017
21
Extra-cellular expansion in the normal, non-infarcted myocardium is associated with worsening of regional myocardial function after acute myocardial infarction. ( 28946878 )
2017
22
Cardiac and Noncardiac Causes of Long-Term Mortality in ST-Segment-Elevation Acute Myocardial Infarction Patients Who Underwent Primary Percutaneous Coronary Intervention. ( 28073848 )
2017
23
Cardiac I+VI^3 integrin expression following acute myocardial infarction in humans. ( 27927700 )
2017
24
Correlation and prognostic role of neutrophil to lymphocyte ratio and SYNTAX score in patients with acute myocardial infarction treated with percutaneous coronary intervention: A six-year experience. ( 28529092 )
2017
25
Adherence Tradeoff to Multiple Preventive Therapies and All-Cause Mortality After Acute Myocardial Infarction. ( 28935030 )
2017
26
Mobilized Muse Cells After Acute Myocardial Infarction Predict Cardiac Function and Remodeling in the Chronic Phase. ( 28931784 )
2017
27
Letter by NAogele Regarding Article, "Effect of Omega-3 Acid Ethyl Esters on Left Ventricular Remodeling After Acute Myocardial Infarction: The OMEGA-REMODEL Randomized Clinical Trial". ( 28069717 )
2017
28
Magnitude and Characteristics of Patients Who Survived an Acute Myocardial Infarction. ( 28947562 )
2017
29
Acute myocardial infarction can be ruled out with a single high-sensitivity cardiac troponin T level. ( 28924057 )
2017
30
Association between retinal vein occlusion and an increased risk of acute myocardial infarction: A nationwide population-based follow-up study. ( 28898259 )
2017
31
Does This Patient Have Acute Myocardial Infarction? ( 28062638 )
2017
32
Predictors of Acute Myocardial Infarction. ( 28925650 )
2017
33
Impact of Morning Onset on the Incidence of Recurrent Acute Coronary Syndrome and Progression of Coronary Atherosclerosis in Acute Myocardial Infarction. ( 28090071 )
2017
34
Cardiac Cell Therapies for the Treatment of Acute Myocardial Infarction: A Meta-Analysis from Mouse Studies. ( 28535507 )
2017
35
A Whole Blood Molecular Signature for Acute Myocardial Infarction. ( 28947747 )
2017
36
Rationale and Design of a Clinical Trial to Evaluate the Safety and Efficacy of Intracoronary Infusion of Allogeneic Human CARdiac stEm Cells in Patients with Acute Myocardial Infarction and Left Ventricular Dysfunction: The Randomized Multicenter Double-Blind Controlled CAREMI Trial. ( 28533209 )
2017
37
Serum Uric Acid Could Differentiate Acute Myocardial Infarction and Unstable Angina Pectoris in Hyperuricemic Acute Coronary Syndrome Patients. ( 28790542 )
2017
38
COLIN trial: Value of colchicine in the treatment of patients with acute myocardial infarction and inflammatory response. ( 28065445 )
2017
39
The prognostic value of shock index for the outcomes of acute myocardial infarction patients: A systematic review and meta-analysis. ( 28930837 )
2017
40
In-hospital outcomes of acute myocardial infarction with cardiogenic shock caused by right coronary artery occlusion vs. left coronary artery occlusion. ( 28918455 )
2017
41
Changes in One-Year Mortality in Elderly Patients Admitted with Acute Myocardial Infarction in Relation with Early Management. ( 28065766 )
2017
42
Prognostic value of plasma apelin concentrations at admission in patients with ST-segment elevation acute myocardial infarction. ( 27889567 )
2017
43
Educational level and 30-day outcomes after hospitalization for acute myocardial infarction in Italy. ( 28069004 )
2017
44
The Neuroprotective Strategic Analysis for Patients with Acute Myocardial Infarction Combined with Hypoxic Ischemic Encephalopathy in ICU. ( 28065791 )
2017
45
Is type D personality an independent risk factor for recurrent myocardial infarction or all-cause mortality in post-acute myocardial infarction patients? ( 28071958 )
2017
46
Moving Beyond SHOCK: New Paradigms in the Management of Acute Myocardial Infarction Complicated by Cardiogenic Shock. ( 28024554 )
2017
47
"30-minute-delta" of high-sensitivity troponin I improves diagnostic performance in acute myocardial infarction. ( 28941733 )
2017
48
Benefits of Statin Therapy in Patients With Acute Myocardial Infarction With Serum Low-Density Lipoprotein Cholesterol a8o 50A mg/dl. ( 28532771 )
2017
49
Quality of Acute Myocardial Infarction Care in Canada: A 10-Year Review of 30-Day In-Hospital Mortality and 30-Day Hospital Readmission. ( 28941611 )
2017
50
Inferior Wall Acute Myocardial Infarction: Not as Preload Dependent as Once Thought? ( 28089058 )
2017

Variations for Acute Myocardial Infarction

Copy number variations for Acute Myocardial Infarction from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 210497 6 30400000 36600000 Amplification C4B Acute myocardial infarction

Expression for Acute Myocardial Infarction

LifeMap Discovery
Genes differentially expressed in tissues of Acute Myocardial Infarction patients vs. healthy controls: 35
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1 EGR3 early growth response 3 Blood + 5.52 0.000
2 LOC286058 uncharacterized LOC286058 Blood + 4.73 0.000
3 CXCL8 chemokine (C-X-C motif) ligand 8 Blood + 3.51 0.004
4 LEP leptin Heart + 3.45 0.011
5 ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein Blood + 3.18 0.007
Search GEO for disease gene expression data for Acute Myocardial Infarction.

Pathways for Acute Myocardial Infarction

GO Terms for Acute Myocardial Infarction

Cellular components related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.93 ACE CRP EDN1 F3 MMP9 NPPA
2 extracellular exosome GO:0070062 9.77 ACE CKB CRP F3 FABP3 MB
3 extracellular matrix GO:0031012 9.65 F3 MMP9 PLAT SERPINE1 VWF
4 platelet alpha granule lumen GO:0031093 9.63 SERPINE1 SERPINF2 VWF
5 extracellular space GO:0005615 9.47 ACE CKB CRP EDN1 F3 FABP3
6 troponin complex GO:0005861 9.43 TNNI3 TNNT2
7 cardiac myofibril GO:0097512 9.4 TNNI3 TNNT2
8 Weibel-Palade body GO:0033093 9.37 EDN1 VWF
9 cardiac Troponin complex GO:1990584 9.32 TNNI3 TNNT2

Biological processes related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

(show all 21)
id Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.73 F3 PLAT SERPINC1 VWF
2 heart development GO:0007507 9.71 EDN1 MB TNNI3
3 platelet degranulation GO:0002576 9.62 SELP SERPINE1 SERPINF2 VWF
4 response to muscle stretch GO:0035994 9.6 EDN1 NPPA
5 heart contraction GO:0060047 9.58 ACE TNNI3
6 regulation of blood vessel diameter GO:0097746 9.58 ACE NPPB
7 hemostasis GO:0007599 9.58 F3 SERPINC1 VWF
8 negative regulation of blood coagulation GO:0030195 9.57 EDN1 SERPINE1
9 positive regulation of renal sodium excretion GO:0035815 9.56 EDN1 NPPB
10 positive regulation of urine volume GO:0035810 9.55 EDN1 NPPB
11 negative regulation of fibrinolysis GO:0051918 9.52 SERPINE1 SERPINF2
12 negative regulation of ATPase activity GO:0032780 9.51 TNNI3 TNNT2
13 receptor guanylyl cyclase signaling pathway GO:0007168 9.49 NPPA NPPB
14 body fluid secretion GO:0007589 9.48 EDN1 NPPB
15 fibrinolysis GO:0042730 9.43 PLAT SERPINE1 SERPINF2
16 negative regulation of plasminogen activation GO:0010757 9.37 SERPINE1 SERPINF2
17 regulation of blood vessel size GO:0050880 9.33 EDN1 NPPA NPPB
18 cell growth involved in cardiac muscle cell development GO:0061049 9.29 NPPA
19 regulation of blood pressure GO:0008217 9.26 ACE EDN1 NPPA NPPB
20 negative regulation of systemic arterial blood pressure GO:0003085 9.16 NPPA
21 response to hypoxia GO:0001666 8.92 EDN1 MB NPPA PLAT

Molecular functions related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.55 EDN1 NPPA NPPB PLAT SERPINE1
2 serine-type endopeptidase inhibitor activity GO:0004867 9.54 SERPINC1 SERPINE1 SERPINF2
3 peptide hormone receptor binding GO:0051428 9.02 NPPA
4 protease binding GO:0002020 9.02 F3 SERPINC1 SERPINE1 SERPINF2 VWF
5 troponin C binding GO:0030172 8.96 TNNI3 TNNT2
6 protein binding GO:0005515 10.19 ADRB1 CKB CRP EDN1 F3 FABP3

Sources for Acute Myocardial Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
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36 IUPHAR
37 KEGG
38 LifeMap
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59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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