MCID: ACT076
MIFTS: 42

Acute Myocarditis malady

Categories: Cardiovascular diseases, Rare diseases

Aliases & Classifications for Acute Myocarditis

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Aliases & Descriptions for Acute Myocarditis:

Name: Acute Myocarditis 10 47 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:3951
ICD1027 I40, I40.9
ICD9CM29 422, 422.90
NCIt42 C35206
UMLS65 C0155686

Summaries for Acute Myocarditis

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MalaCards based summary: Acute Myocarditis is related to septic myocarditis and myocarditis. An important gene associated with Acute Myocarditis is TNC (Tenascin C), and among its related pathways are IL-15 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and African trypanosomiasis. Affiliated tissues include heart, breast and thyroid, and related mouse phenotype mortality/aging.

Related Diseases for Acute Myocarditis

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Diseases in the Myocarditis family:

acute myocarditis Autoimmune Myocarditis
Infectious Myocarditis Post-Infectious Myocarditis

Diseases related to Acute Myocarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 108)
idRelated DiseaseScoreTop Affiliating Genes
1septic myocarditis29.9ACE, CUX2
2myocarditis10.9
3giant cell myocarditis10.6
4developmental and speech delay due to sox5 deficiency10.5FAS, FASLG
5vulvar benign neoplasm10.5FAS, FASLG
6obesity due to prohormone convertase i deficiency10.5TNNI3, TNNT2
7coronary thrombosis10.4TNNI3, TNNT2
8transient retinal arterial occlusion10.4TNNI3, TNNT2
9skeletal tuberculosis10.4FAS, FASLG
10gastric cancer10.4TNNI3, TNNT2
11lymphomatous thyroiditis10.4FAS, FASLG
12peripheral artery disease10.4TNNI3, TNNT2
13chromosome 3q29 microduplication syndrome10.3TNNI3, TNNT2
14myocardial infarction10.3
15heart aneurysm10.3TNNI3, TNNT2
16hepatic vascular disease10.3TNNT2, ZIC3
17withdrawal disorder10.3TNNI3, TNNT2
18cardiomyopathy10.3
19fiedler's myocarditis10.3
20gonococcal keratitis10.2TNNI3, ZIC3
21septal myocardial infarction10.2ACE, TNNT2
22acute myocardial infarction10.2
23rh deficiency syndrome10.2TNNI3, TNNT2
24dilated cardiomyopathy10.2
25transverse vaginal septum10.2SDHA, TNNI3, TNNT2
26atrioventricular block10.1
27cryoglobulinemia10.1ACE, FAS
28influenza10.0
29intraocular lymphoma10.0ACE, TNNT2
30aneurysm10.0
31single ventricular heart10.0ACE, FAS, FASLG
32systemic lupus erythematosus10.0
33lupus erythematosus10.0
34cardiogenic shock10.0
35ceroid lipofuscinosis, neuronal, 610.0ACE, TNC
36prostate squamous cell carcinoma9.9ACE, TNNT2
37spondyloarthropathy 19.9FAS, FASLG
38pericarditis9.9
39heterophyiasis9.9ACE, TNNI3, TNNT2
40meige syndrome9.9ACE, TNNI3, TNNT2
41specific developmental disorder9.9ACE, TNNI3, TNNT2
42pneumonia9.9
43eosinophilia9.9
44adult acute lymphocytic leukemia9.8ACE, TNNI3, TNNT2
45mitochondrial metabolism disease9.8ACE, TNNI3, TNNT2
46adams-oliver syndrome 59.8ACE, TNNI3
47drug-induced hepatitis9.8ACE, TNNI3, TNNT2
48pheochromocytoma9.8
49malaria9.8
50cardiac tamponade9.8

Comorbidity relations with Acute Myocarditis via Phenotypic Disease Network (PDN):


Heart DiseaseIschemic Heart Disease

Graphical network of the top 20 diseases related to Acute Myocarditis:



Diseases related to acute myocarditis

Symptoms for Acute Myocarditis

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Drugs & Therapeutics for Acute Myocarditis

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Drugs for Acute Myocarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Ferrosoferric OxidePhase 2, Phase 362
2Parenteral Nutrition SolutionsPhase 2, Phase 371
3Pharmaceutical SolutionsPhase 2, Phase 37004
4HematinicsPhase 2, Phase 31121
5
IronapprovedPhase 210217439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Dexiron
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
Ed-In-Sol
 
Eisen
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feraheme
Feronate
Ferretts
Ferrlecit
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Infufer
Iron
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Venofer
Vitedyn-Slo
Yieronia
fer
ferrous ascorbate
ferrous fumarate
ferrous gluconate
ferrous glycine sulfate
ferrous iron
ferrous succinate
ferrous sulfate
hierro
6Tissue Inhibitor of Metalloproteinase-110
7Tissue Inhibitor of Metalloproteinases10
8TIMP1 protein, human10
9Matrix Metalloproteinase Inhibitors14
10Protease Inhibitors4558
11HIV Protease Inhibitors4558
12Protective Agents5651
13Antioxidants2442

Interventional clinical trials:

(show all 17)
idNameStatusNCT IDPhase
1DEtection of Cellular Inflammation With FERumoxytol in the HEARTRecruitingNCT02319278Phase 2, Phase 3
2IRon Nanoparticle Enhanced MRI in the Assessment of Myocardial infarctioNRecruitingNCT01995799Phase 2
3Dilated cardiomYopathy iNtervention With Allogeneic MyocardIally-regenerative Cells (DYNAMIC)Active, not recruitingNCT02293603Phase 1
4Cardiac Magnetic Resonance in Acute MyocarditisCompletedNCT02299856
5CMR in Patients With MyocarditisCompletedNCT01962584
6Role of Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of Metalloproteinases (TIMPs) in Children With MyocarditisCompletedNCT00693134
7Detection of Enterovirus RNA in Atheromatous LesionsCompletedNCT00674531
8German Centre for Cardiovascular Research Cardiomyopathy RegisterRecruitingNCT02187263
9Short and Long Term Outcomes of Acute Coronary Syndrome in Patients With Non Obstructive Coronary AtherosclerosisRecruitingNCT02655718
10Oxidant-antioxidant Activity, Free Radicle Activity, Immune Response and Biomarkers in Extracorporeal Membrane Oxygenation (ECMO) PatientsRecruitingNCT01089036
11Evaluation of Myocardial Iron Deposition in Patients of Heart Failure Using T2* MR ImagingRecruitingNCT02527330
12Stockholm Myocardial Infarction With Normal Coronaries (SMINC)-2 Study on Diagnosis Made by Cardiac MRIRecruitingNCT02318498
13Cohort of Patients Infected by an ArbovirusRecruitingNCT01099852
14Inflammation, Cardiac Sympathetic Innervation, and Arrhythmic Sudden DeathRecruitingNCT01919983
15International Myocarditis RegistryEnrolling by invitationNCT01307735
16French National Observatory Tracking Viral Myocarditis: Mortality, Cardiovascular Events, Sequels on (Magnetic Resonance Imaging) MRINot yet recruitingNCT02717143
17Transient ECG Changes in Patients With Acute Biliary DiseaseNot yet recruitingNCT01706068

Search NIH Clinical Center for Acute Myocarditis

Genetic Tests for Acute Myocarditis

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Anatomical Context for Acute Myocarditis

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MalaCards organs/tissues related to Acute Myocarditis:

33
Heart, Breast, Thyroid, T cells, Prostate, Liver, Kidney

Animal Models for Acute Myocarditis or affiliated genes

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MGI Mouse Phenotypes related to Acute Myocarditis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107686.7ACE, CUX2, FAS, FASLG, SDHA, TNNI3

Publications for Acute Myocarditis

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Articles related to Acute Myocarditis:

(show top 50)    (show all 439)
idTitleAuthorsYear
1
Relationship between T-wave inversion and transmural myocardial edema as evidenced by cardiac magnetic resonance in patients with clinically suspected acute myocarditis: clinical and prognostic implications. (27178316)
2016
2
Acute respiratory distress syndrome and acute myocarditis developed in a previously healthy adult with influenza B. (26728359)
2016
3
Acute myocarditis associated with novel Middle east respiratory syndrome coronavirus. (26922692)
2016
4
Diagnostic implications of magnetic resonance feature tracking derived myocardial strain parameters in acute myocarditis. (26724669)
2016
5
Atrial Fibrillation Due to Acute Myocarditis During Dengue Haemorrhagic Fever. (26500943)
2015
6
Diagnosis of acute myocarditis with dual source cardiac tomography. (25464460)
2015
7
Acute Myocarditis in a Patient with Newly Diagnosed Granulomatosis with Polyangiitis. (26770838)
2015
8
Ultra-low dose comprehensive cardiac CT imaging in a patient with acute myocarditis. (25439792)
2014
9
Formation of a fibrin net on the polypropylene membrane oxygenator used for percutaneous cardiopulmonary support in a patient with acute myocarditis. (24875892)
2014
10
Acute myocarditis associated with coxsackievirus b4 mimicking influenza myocarditis: electron microscopy detection of causal virus of myocarditis. (24366591)
2013
11
Electrocardiographic findings and myocardial damage in acute myocarditis detected by cardiac magnetic resonance. (22388951)
2012
12
Altered left ventricular tissue velocities, deformation and twist in children and young adults with acute myocarditis and normal ejection fraction. (22101088)
2012
13
Rapidly fatal community-acquired pneumonia due to Klebsiella pneumoniae complicated with acute myocarditis and accelerated idioventricular rhythm. (22153763)
2012
14
A delayed diagnosis of acute myocarditis: diagnostic value of cardiovascular magnetic resonance imaging. (22892447)
2012
15
Churg-Strauss syndrome presenting with acute myocarditis and cardiogenic shock. (21963398)
2012
16
Acute myocarditis mimicking reverse Takotsubo cardiomyopathy. (21242509)
2011
17
Late enhancement detected by cardiac magnetic resonance imaging in acute myocarditis mimicking acute myocardial infarction: location patterns and lack of correlation with systolic function. (18163015)
2007
18
Diagnostic value of ECG-gated multidetector computed tomography in the early phase of suspected acute myocarditis. A preliminary comparative study with cardiac MRI. (16953372)
2007
19
Muronomab-CD3 for pediatric acute myocarditis. (17165111)
2007
20
Acute myocarditis associated with cardiac amyloidosis manifesting as transient complete atrioventricular block and slow ventricular tachycardia. (15964086)
2006
21
Recovery of acute myocarditis with biventricular assist device in infant. (16274783)
2005
22
Short-term prognostic value of initial serum levels of interleukin-10 in patients with acute myocarditis. (15642541)
2005
23
Structural and electrical ventricular remodeling in rat acute myocarditis and subsequent heart failure. (15306225)
2004
24
Expression of tumor necrosis factor ligand superfamily costimulatory molecules CD27L, CD30L, OX40L and 4-1BBL in the heart of patients with acute myocarditis and dilated cardiomyopathy. (12031769)
2002
25
Acute myocarditis (predominately lymphocytic) causing sudden death without heart failure. (11704019)
2001
26
Healing of acute myocarditis with left ventricular assist device: morphological recovery and evolution to the aspecific features of dilated cardiomyopathy. (11214703)
2001
27
Acute myocarditis and left ventricular "hypertrophy". (11000592)
2000
28
Effects of intranasal administration of recombinant murine interferon-gamma on murine acute myocarditis caused by encephalomyocarditis virus. (9529271)
1998
29
Extracorporeal membrane oxygenation in treatment of cardiogenic shock caused by acute myocarditis. (9610063)
1998
30
Expression of cytokine mRNAs in murine hearts with acute myocarditis caused by coxsackievirus b3. (9370955)
1997
31
Images in cardiovascular medicine. Acute myocarditis masquerading as acute myocardial infarction. (7882500)
1995
32
Restricted usage of T cell receptor V alpha-V beta genes in infiltrating cells in the hearts of patients with acute myocarditis and dilated cardiomyopathy. (7635939)
1995
33
Acute myocarditis. Rapid diagnosis by PCR in children. (8026015)
1994
34
Coronary arterial occlusion and myocardial infarction in acute myocarditis. (2303303)
1990
35
The use of intravenous ribavirin to treat influenza virus-associated acute myocarditis. (2775346)
1989
36
Detection of acute myocarditis using nuclear magnetic resonance imaging. (3400714)
1988
37
Increase in serum free fatty acids, phospholipids and reduction in total cholesterol in acute myocarditis produced by scorpion (Buthus tamulus) venom injection in dogs. (3570321)
1986
38
Hemodynamic studies and response to a combined therapy of nitroglycerin ointment and dopamine in patients with acute myocarditis. (3939646)
1985
39
Liver glycogen depletion in acute myocarditis produced by scorpion venom (buthus tamulus). (6724623)
1984
40
Acute myocarditis associated with hepatitis B virus infection--a case report. (6629408)
1983
41
Left atrial myxoma. Clinical presentation suggesting acute myocarditis. (4479150)
1974
42
Acute myocarditis in rats inoculated with Trypanosoma cruzi: study of animals sacrificed between the fourth and twenty-ninth day after infection. (4627073)
1972
43
Coxsackie B5 virus responsible for acute myocarditis inucklings. (5439221)
1970
44
Contribution to the enzymic diagnosis of acute myocarditis, myocardial infarction and cardiogenic shock. (5384064)
1969
45
THE EFFECT OF PHENOBARBITAL ON THE ELECTROCARDIOGRAM IN ACUTE MYOCARDITIS. (14333176)
1965
46
ACUTE MYOCARDITIS IN INFANCY AND CHILDHOOD. (14209575)
1964
47
ACUTE MYOCARDITIS IN THE ADULT. (14214812)
1964
48
Working capacity and heart volume in patients with electrocardiographic abnormalities suggestive of acute myocarditis during various acute infectious diseases. (13508117)
1957
49
Meningococcemia with acute leptomeningitis and acute myocarditis. (21000434)
1946
50

Variations for Acute Myocarditis

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Expression for genes affiliated with Acute Myocarditis

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Search GEO for disease gene expression data for Acute Myocarditis.

Pathways for genes affiliated with Acute Myocarditis

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GO Terms for genes affiliated with Acute Myocarditis

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Biological processes related to Acute Myocarditis according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1necroptotic signaling pathwayGO:009752710.3FAS, FASLG
2response to growth factorGO:007084810.2FAS, FASLG
3negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:190204210.1FAS, FASLG
4activation of cysteine-type endopeptidase activity involved in apoptotic processGO:00069199.8FAS, FASLG
5extrinsic apoptotic signaling pathwayGO:00971919.7FAS, FASLG
6cardiac muscle contractionGO:00600489.7TNNI3, TNNT2
7heart contractionGO:00600479.7ACE, TNNI3
8necroptotic processGO:00702669.5FAS, FASLG

Sources for Acute Myocarditis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet