MCID: ACT076
MIFTS: 37

Acute Myocarditis malady

Categories: Cardiovascular diseases, Rare diseases

Aliases & Classifications for Acute Myocarditis

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Aliases & Descriptions for Acute Myocarditis:

Name: Acute Myocarditis 10 47 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:3951
ICD1027 I40, I40.9
ICD9CM29 422, 422.90
NCIt42 C35206
UMLS65 C0155686

Summaries for Acute Myocarditis

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MalaCards based summary: Acute Myocarditis is related to septic myocarditis and gastric cancer. An important gene associated with Acute Myocarditis is TNC (Tenascin C), and among its related pathways are IL-15 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and African trypanosomiasis. Affiliated tissues include heart, thyroid and breast, and related mouse phenotype mortality/aging.

Related Diseases for Acute Myocarditis

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Diseases in the Myocarditis family:

acute myocarditis Autoimmune Myocarditis
Infectious Myocarditis Post-Infectious Myocarditis

Diseases related to Acute Myocarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 304)
idRelated DiseaseScoreTop Affiliating Genes
1septic myocarditis30.5ACE, CUX2
2gastric cancer30.1TNNI3, TNNT2
3fiedler's myocarditis10.6
4giant cell myocarditis10.6
5developmental and speech delay due to sox5 deficiency10.4FAS, FASLG
6vulvar benign neoplasm10.3FAS, FASLG
7obesity due to prohormone convertase i deficiency10.3TNNI3, TNNT2
8coronary thrombosis10.3TNNI3, TNNT2
9transient retinal arterial occlusion10.3TNNI3, TNNT2
10skeletal tuberculosis10.3FAS, FASLG
11endotheliitis10.2
12lymphomatous thyroiditis10.2FAS, FASLG
13peripheral artery disease10.2TNNI3, TNNT2
14chromosome 3q29 microduplication syndrome10.2TNNI3, TNNT2
15hepatic vascular disease10.2TNNT2, ZIC3
16heart aneurysm10.2TNNI3, TNNT2
17lymphoma10.2
18neuronitis10.2
19withdrawal disorder10.2TNNI3, TNNT2
20lung cancer10.2
21arthritis10.2
22leukemia10.2
23gonococcal keratitis10.2TNNI3, ZIC3
24septal myocardial infarction10.1ACE, TNNT2
25spondyloarthropathy 110.1FAS, FASLG
26rheumatoid arthritis10.1
27breast cancer10.1
28prostatitis10.1
29tuberculosis10.1
30transverse vaginal septum10.1SDHA, TNNI3, TNNT2
31rh deficiency syndrome10.1TNNI3, TNNT2
32cryoglobulinemia10.1ACE, FAS
33prostate cancer10.0
34keloids10.0
35artery disease10.0
36cervicitis10.0
37ischemia10.0
38pneumonia10.0
39myeloid leukemia10.0
40spasticity10.0
41intraocular lymphoma10.0ACE, TNNT2
42single ventricular heart10.0ACE, FAS, FASLG
43colorectal cancer10.0
44asthma10.0
45coronary artery disease10.0
46congestive heart failure10.0
47hepatitis10.0
48thrombocytopenia10.0
49colitis10.0
50myeloma10.0

Graphical network of the top 20 diseases related to Acute Myocarditis:



Diseases related to acute myocarditis

Symptoms for Acute Myocarditis

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Drugs & Therapeutics for Acute Myocarditis

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Drugs for Acute Myocarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Ferrosoferric OxidePhase 2, Phase 362
2Parenteral Nutrition SolutionsPhase 2, Phase 371
3Pharmaceutical SolutionsPhase 2, Phase 37004
4HematinicsPhase 2, Phase 31121
5
IronapprovedPhase 210217439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Dexiron
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
Ed-In-Sol
 
Eisen
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feraheme
Feronate
Ferretts
Ferrlecit
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Infufer
Iron
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Venofer
Vitedyn-Slo
Yieronia
fer
ferrous ascorbate
ferrous fumarate
ferrous gluconate
ferrous glycine sulfate
ferrous iron
ferrous succinate
ferrous sulfate
hierro
6Tissue Inhibitor of Metalloproteinase-110
7Tissue Inhibitor of Metalloproteinases10
8TIMP1 protein, human10
9Matrix Metalloproteinase Inhibitors14
10Protease Inhibitors4558
11HIV Protease Inhibitors4558
12Protective Agents5651
13Antioxidants2442

Interventional clinical trials:

(show all 17)
idNameStatusNCT IDPhase
1DEtection of Cellular Inflammation With FERumoxytol in the HEARTRecruitingNCT02319278Phase 2, Phase 3
2IRon Nanoparticle Enhanced MRI in the Assessment of Myocardial infarctioNRecruitingNCT01995799Phase 2
3Dilated cardiomYopathy iNtervention With Allogeneic MyocardIally-regenerative Cells (DYNAMIC)Active, not recruitingNCT02293603Phase 1
4Cardiac Magnetic Resonance in Acute MyocarditisCompletedNCT02299856
5CMR in Patients With MyocarditisCompletedNCT01962584
6Role of Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of Metalloproteinases (TIMPs) in Children With MyocarditisCompletedNCT00693134
7Detection of Enterovirus RNA in Atheromatous LesionsCompletedNCT00674531
8German Centre for Cardiovascular Research Cardiomyopathy RegisterRecruitingNCT02187263
9Short and Long Term Outcomes of Acute Coronary Syndrome in Patients With Non Obstructive Coronary AtherosclerosisRecruitingNCT02655718
10Oxidant-antioxidant Activity, Free Radicle Activity, Immune Response and Biomarkers in Extracorporeal Membrane Oxygenation (ECMO) PatientsRecruitingNCT01089036
11Evaluation of Myocardial Iron Deposition in Patients of Heart Failure Using T2* MR ImagingRecruitingNCT02527330
12Stockholm Myocardial Infarction With Normal Coronaries (SMINC)-2 Study on Diagnosis Made by Cardiac MRIRecruitingNCT02318498
13Cohort of Patients Infected by an ArbovirusRecruitingNCT01099852
14Inflammation, Cardiac Sympathetic Innervation, and Arrhythmic Sudden DeathRecruitingNCT01919983
15International Myocarditis RegistryEnrolling by invitationNCT01307735
16French National Observatory Tracking Viral Myocarditis: Mortality, Cardiovascular Events, Sequels on (Magnetic Resonance Imaging) MRINot yet recruitingNCT02717143
17Transient ECG Changes in Patients With Acute Biliary DiseaseNot yet recruitingNCT01706068

Search NIH Clinical Center for Acute Myocarditis

Genetic Tests for Acute Myocarditis

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Anatomical Context for Acute Myocarditis

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MalaCards organs/tissues related to Acute Myocarditis:

33
Heart, Thyroid, Breast, Bone, Lung, T cells, Colon

Animal Models for Acute Myocarditis or affiliated genes

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MGI Mouse Phenotypes related to Acute Myocarditis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107686.7ACE, CUX2, FAS, FASLG, SDHA, TNNI3

Publications for Acute Myocarditis

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Articles related to Acute Myocarditis:

(show top 50)    (show all 419)
idTitleAuthorsYear
1
Expression of 3-phosphoinositide-dependent protein kinase 1 in colorectal cancer as a potential therapeutic target. (26055151)
2015
2
OP010. Medication-induced microscopic colitis: do recency and duration of use matter? (25718276)
2015
3
Low Vitamin D Status is Associated with Increased Titers of Thyroid Stimulating Hormone Receptor Antibodies in Graves' Disease. (25370319)
2014
4
Ligand-dependent EphB1 signaling suppresses glioma invasion and correlates with patient survival. (24121831)
2013
5
Release of macrophage migration inhibitory factor by neuroendocrine-differentiated LNCaP cells sustains the proliferation and survival of prostate cancer cells. (23207293)
2013
6
The mental retardation-associated protein srGAP3 regulates survival, proliferation, and differentiation of rat embryonic neural stem/progenitor cells. (23311320)
2013
7
Compartment syndrome of the hand from prolonged immobilization secondary to drug overdose. (23340119)
2013
8
MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery. (23532818)
2013
9
Liposomal doxorubicin-based treatment in a preclinical model of adrenocortical carcinoma. (22407999)
2012
10
Association of CACNG6 polymorphisms with aspirin-intolerance asthmatics in a Korean population. (20860846)
2010
11
Antibiotic treatment for bacterial meningitis caused by Listeria monocytogenes in a patient with multiple myeloma. (20112040)
2010
12
Percutaneous radiofrequency lesions adjacent to the dorsal root ganglion alleviate spasticity and pain in children with cerebral palsy: pilot study in 17 patients. (20569438)
2010
13
Differential sensitivity of "old" versus "new" APOBEC3G to human immunodeficiency virus type 1 vif. (19004939)
2009
14
Relevance of declines in serum human chorionic gonadotropin levels to the management of persistent ectopic pregnancy. (20149048)
2009
15
Castleman's disease arising from an intrapulmonary lymph node. (19830523)
2009
16
Complete deletion of the aprataxin gene: ataxia with oculomotor apraxia type 1 with severe phenotype and cognitive deficit. (18202221)
2008
17
IL-1beta (+3954C/T) polymorphism could protect human immunodeficiency virus (HIV)-infected patients on highly active antiretroviral treatment (HAART) against lipodystrophic syndrome. (18344712)
2008
18
Amplification of EMSY gene in a subset of sporadic pancreatic adenocarcinomas. (18787609)
2008
19
Sustained metabolic control and low rates of severe hypoglycaemic episodes in preschool diabetic children treated with continuous subcutaneous insulin infusion. (17537017)
2007
20
Stimulating erythropoiesis in inflammatory bowel disease associated anemia. (17828809)
2007
21
Expression of beta-catenin, E-cadherin and APC in canine mammary tumors. (17970048)
2007
22
MTHFR 677C-->T and 1298A-->C polymorphisms: evaluation of maternal genotypic risk and association with level of neural tube defect. (17085942)
2007
23
Neurological manifestations of cervical spondylosis: an overview of signs, symptoms, and pathophysiology. (17204875)
2007
24
An analysis of the UNOS liver transplant registry: high serum alpha-fetoprotein does not justify an increase in MELD points for suspected hepatocellular carcinoma. (17004260)
2006
25
An activation domain in the C-terminal subunit of HCF-1 is important for transactivation by VP16 and LZIP. (12271126)
2002
26
Heterologous expression of WT and mutant photoreceptor peripherin/rds in Madin Darby canine kidney cells: an assessment of fusogenic function. (11950237)
2002
27
Chronic idiopathic urticaria: a family study. (12197577)
2002
28
GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model. (12087127)
2002
29
E3 ligase activity of RING finger proteins that interact with Hip-2, a human ubiquitin-conjugating enzyme. (11513855)
2001
30
Risk factors in childhood that lead to the development of conduct disorder and antisocial personality disorder. (11196010)
2001
31
Galactosylation of N-linked oligosaccharides by human beta-1,4- galactosyltransferases I, II, III, IV, V, and VI expressed in Sf-9 cells. (11588157)
2001
32
Allele-dependent transcriptional regulation of the human integrin alpha2 gene. (11238113)
2001
33
Suppressing HER2/neu-mediated cell transformation by transcriptional repressors. (15687599)
2000
34
Elevated neointimal endothelin-1 in transplantation-associated arteriosclerosis of renal allograft recipients. (9734624)
1998
35
A PMLRARalpha transgene initiates murine acute promyelocytic leukemia. (9122233)
1997
36
Betaine for homocystinuria. (9025725)
1997
37
Generation of active oxygen species from advanced glycation end-products (AGE) under ultraviolet light A (UVA) irradiation. (9199187)
1997
38
Plasmin-catalyzed proteolysis in colorectal neoplasia. (7553650)
1995
39
Cushing's syndrome due to primary pigmented nodular adrenocortical disease--a case report reviews of the literature. (7626560)
1995
40
Is there IgA of gut mucosal origin in the serum of HIV1 infected patients? (7517378)
1994
41
One-stage transverse distal penile/preputial island flap urethroplasty for urethral stricture. (8239549)
1993
42
Treatment of enterocutaneous and colocutaneous fistulas with early surgery or somatostatin analog. (1351835)
1992
43
Cervical instability as an unusual manifestation of Hajdu-Cheney syndrome of acroosteolysis. (2347142)
1990
44
Glutaric acidemia type II. Comparison of pathologic features in two infants. (3178428)
1988
45
Antibiotic treatment of acute salpingitis. A study of plasma concentrations of two tetracyclines (doxycycline and lymecycline). (7090752)
1982
46
Instillation of fibrinolytic enzymes in the treatment of pleural empyema. (6179231)
1982
47
Tricuspid atresia. An electrocardiographic study. (13915106)
1962
48
Anuria following phenylbutazone therapy. (14383969)
1955
49
Embryoma of kidney (Wilms' tumor) in children. (18137842)
1949
50

Variations for Acute Myocarditis

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Expression for genes affiliated with Acute Myocarditis

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Search GEO for disease gene expression data for Acute Myocarditis.

Pathways for genes affiliated with Acute Myocarditis

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GO Terms for genes affiliated with Acute Myocarditis

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Biological processes related to Acute Myocarditis according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1necroptotic signaling pathwayGO:009752710.3FAS, FASLG
2response to growth factorGO:007084810.2FAS, FASLG
3negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:190204210.1FAS, FASLG
4activation of cysteine-type endopeptidase activity involved in apoptotic processGO:00069199.8FAS, FASLG
5extrinsic apoptotic signaling pathwayGO:00971919.7FAS, FASLG
6cardiac muscle contractionGO:00600489.7TNNI3, TNNT2
7heart contractionGO:00600479.7ACE, TNNI3
8necroptotic processGO:00702669.5FAS, FASLG

Sources for Acute Myocarditis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet