MCID: ACT027
MIFTS: 57

Acute Pancreatitis malady

Categories: Gastrointestinal diseases, Endocrine diseases, Genetic diseases, Rare diseases, Bone diseases, Immune diseases

Aliases & Classifications for Acute Pancreatitis

Aliases & Descriptions for Acute Pancreatitis:

Name: Acute Pancreatitis 12 52 14 69
Acute Pancreatitis [ambiguous] 12 29
Pancreatitis, Acute Necrotizing 69
Acute Necrotizing Pancreatitis 12
Acute Pancreatitis Unspecified 12
Pancreatitis Necrotizing 12
Necrotizing Pancreatitis 52
Acute Pancreatitis Nos 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2913
ICD10 33 K85 K85.9
ICD9CM 35 577.0
NCIt 47 C95437
UMLS 69 C0001339

Summaries for Acute Pancreatitis

MalaCards based summary : Acute Pancreatitis, also known as acute pancreatitis [ambiguous], is related to gastric dilatation and neuropathy. An important gene associated with Acute Pancreatitis is CRP (C-Reactive Protein), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Cefoperazone and Chlorhexidine have been mentioned in the context of this disorder. Affiliated tissues include pancreas, lung and neutrophil, and related phenotypes are Increased shRNA abundance (Z-score > 2) and homeostasis/metabolism

Wikipedia : 71 Acute pancreatitis or acute pancreatic necrosis is a sudden inflammation of the pancreas. It can have... more...

Related Diseases for Acute Pancreatitis

Diseases in the Pancreatitis family:

Pancreatitis, Hereditary Acute Pancreatitis
Prss1-Related Hereditary Pancreatitis Autoimmune Pancreatitis
Cftr-Related Hereditary Pancreatitis Ctrc-Related Hereditary Pancreatitis
Spink1-Related Hereditary Pancreatitis Autoimmune Pancreatitis Type 2
Autoimmune Pancreatitis Type 1 Recurrent Acute Pancreatitis

Diseases related to Acute Pancreatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 383)
id Related Disease Score Top Affiliating Genes
1 gastric dilatation 29.9 CXCL8 IL10 IL6
2 neuropathy 29.5 CRP CXCL8 IL6
3 blue toe syndrome 29.4 CXCL8 IL10 IL6
4 keratomalacia 29.4 CRP CXCL8 IL10 IL6
5 alcoholic hepatitis 29.4 CXCL8 ELANE IL10 IL6
6 typhoid fever 29.3 CCK CXCL8 SST TMPRSS15
7 netherton syndrome 28.8 CCK ELANE PNLIP REG3A SCT SPINK1
8 recurrent acute pancreatitis 12.1
9 pancreatitis 11.8
10 hypertriglyceridemia 11.2
11 lipoprotein lipase deficiency 11.1
12 pancreatitis, pediatric 10.8
13 coloboma of iris 10.3 CRP IL6
14 joint disorders 10.3 CRP IL6 LPL
15 multiple mitochondrial dysfunctions syndrome 10.3 CRP IL10 IL6
16 neonatal hypoxic and ischemic brain injury 10.3 CXCL8 IL10 IL6
17 esotropia 10.3 CRP IL6 MPO
18 childhood electroclinical syndrome 10.3 CXCL8 IL10 IL6
19 cicatricial lagophthalmos 10.3 CRP CXCL8 IL6
20 laryngotracheoesophageal cleft type 2 10.3 CRP IL18 IL6
21 plummer's disease 10.3 CRP IL10 IL6
22 mixed mineral dust pneumoconiosis 10.3 CRP CXCL8 IL6
23 trichomalacia 10.3 CXCL8 IL10 IL6
24 follicular adenoma 10.3 CRP IL10 IL6
25 subacute glomerulonephritis 10.3 CRP ELANE MPO
26 cardiomyopathy diabetes deafness 10.3 CRP CXCL8 ELANE
27 parkinson disease 11 10.3 CXCL8 IL10 MPO
28 benign neonatal seizures 10.3 CRP IL18 IL6
29 autosomal recessive type iv ehlers-danlos syndrome 10.3 CXCL8 IL10 IL6
30 erb-duchenne and dejerine-klumpke palsies 10.3 CXCL8 IL10 IL6
31 strawberry gallbladder 10.3 CRP CXCL8 MPO
32 inappropriate adh syndrome 10.3 CXCL8 IL10 IL6
33 stomatitis 10.3 CXCL8 IL18 IL6
34 labyrinthitis 10.3 CXCL8 IL10 IL6
35 premature menopause 10.3 CRP IL6 REG3A
36 acquired thrombocytopenia 10.3 CXCL8 IL18 IL6
37 myxofibrosarcoma 10.3 LPL SCT SPINK1
38 depressed scar 10.3 CXCL8 IL10 IL6
39 omsk hemorrhagic fever 10.3 CXCL8 ELANE MPO
40 orthostatic proteinuria 10.3 CXCL8 IL18 IL6
41 burns 10.3 CXCL8 IL10 IL6
42 usher syndrome, type 2a 10.3 IL10 IL18 IL6
43 unilateral hypoactive labyrinth 10.3 CRP CXCL8 IL10
44 pyelonephritis 10.3 CRP CXCL8 IL10
45 adnp syndrome 10.3 CXCL8 ELANE IL6
46 classic type lipoma 10.3 CXCL8 IL10 IL6
47 fallopian tube serous adenocarcinoma 10.3 CRP CXCL8 IL10 IL6
48 limb ischemia 10.3 CRP CXCL8 IL6
49 atrophy of prostate 10.2 CRP CXCL8 IL10 IL6
50 myiasis 10.2 CRP CXCL8 IL10 IL6

Comorbidity relations with Acute Pancreatitis via Phenotypic Disease Network (PDN): (show all 39)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Alcohol Abuse
Alcoholic Gastritis Alcoholic Hepatitis
Alcoholic Liver Cirrhosis Atrophic Gastritis
Biliary Tract Disease Biliary Tract Neoplasm
Cholangitis Cholecystitis
Cholestasis Chronic Kidney Failure
Chronic Myocardial Ischemia Deficiency Anemia
Duodenitis Esophageal Disease
Esophagitis Gallbladder Disease
Heart Disease Hepatitis
Hyperlipoproteinemia Type Iv Hypertension, Essential
Hypothyroidism Intestinal Obstruction
Iron Deficiency Anemia Irritable Bowel Syndrome
Ischemic Heart Disease Liver Disease
Mesenteric Artery Ischemia Pancreatic Agenesis 1
Pancreatic Cancer Pancreatitis, Hereditary
Paralytic Ileus Postcholecystectomy Syndrome
Protein-Energy Malnutrition Respiratory Failure
Strawberry Gallbladder

Graphical network of the top 20 diseases related to Acute Pancreatitis:



Diseases related to Acute Pancreatitis

Symptoms & Phenotypes for Acute Pancreatitis

GenomeRNAi Phenotypes related to Acute Pancreatitis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.78 MPO
2 Increased shRNA abundance (Z-score > 2) GR00366-A-113 9.78 CPB1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.78 PLA2G6
4 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.78 SPINK1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.78 MPO
6 Increased shRNA abundance (Z-score > 2) GR00366-A-131 9.78 SPINK1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-157 9.78 MPO
8 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.78 CPB1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.78 PLA2G6
10 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.78 MPO
11 Increased shRNA abundance (Z-score > 2) GR00366-A-186 9.78 MPO
12 Increased shRNA abundance (Z-score > 2) GR00366-A-194 9.78 PLA2G6
13 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.78 SPINK1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.78 SPINK1 CPB1 MPO PLA2G6
15 Increased shRNA abundance (Z-score > 2) GR00366-A-3 9.78 CPB1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.78 CPB1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-36 9.78 MPO
18 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.78 CPB1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-57 9.78 MPO
20 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.78 PLA2G6
21 Increased shRNA abundance (Z-score > 2) GR00366-A-67 9.78 SPINK1
22 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.78 MPO
23 Increased shRNA abundance (Z-score > 2) GR00366-A-70 9.78 MPO
24 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.78 CPB1 PLA2G6
25 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.78 CPB1

MGI Mouse Phenotypes related to Acute Pancreatitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.83 IL10 IL18 IL6 LPL MPO PLA2G6
2 immune system MP:0005387 9.36 CRP CTSB ELANE IL10 IL18 IL6

Drugs & Therapeutics for Acute Pancreatitis

Drugs for Acute Pancreatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 294)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cefoperazone Approved Phase 4 62893-19-0 44185
2
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
3
Meropenem Approved, Investigational Phase 4,Phase 1,Phase 2 119478-56-7 64778 441130
4
Metronidazole Approved Phase 4 443-48-1 4173
5
Somatostatin Approved Phase 4,Phase 3 38916-34-6, 51110-01-1 53481605
6
Acetaminophen Approved Phase 4,Phase 3 103-90-2 1983
7
Clonidine Approved Phase 4 4205-90-7 2803
8
Ropivacaine Approved Phase 4,Phase 2,Phase 3,Phase 1 84057-95-4 71273 175805
9
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
10
Tramadol Approved, Investigational Phase 4,Phase 2,Phase 3 27203-92-5 33741
11
Pancrelipase Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 53608-75-6
12
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
13
Octreotide Approved, Investigational Phase 4 83150-76-9 383414 6400441
14
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
15
Indomethacin Approved, Investigational Phase 4,Phase 3 53-86-1 3715
16
Cilastatin Approved Phase 4 82009-34-5 5280454 6435415
17
Imipenem Approved Phase 4 74431-23-5 104838
18
Ketorolac Approved Phase 4,Phase 2,Phase 3 74103-06-3, 66635-83-4 3826
19
Azathioprine Approved Phase 4 446-86-6 2265
20
Thioguanine Approved Phase 4 154-42-7 2723601
21
Etanercept Approved, Investigational Phase 4 185243-69-0
22
Menthol Approved Phase 4 2216-51-5 16666
23
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
24
Resveratrol Experimental, Investigational Phase 4 501-36-0, 955365-80-7 24856436 445154
25 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1
26 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3,Phase 1
27 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1
28 Anti-Infective Agents, Local Phase 4
29 Antiparasitic Agents Phase 4
30 Antiprotozoal Agents Phase 4
31 Chlorhexidine gluconate Phase 4
32 Dermatologic Agents Phase 4,Phase 2,Phase 3
33 Disinfectants Phase 4
34 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
35 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
36 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
37 Renal Agents Phase 4
38 Sulperazone Phase 4
39 Thienamycins Phase 4
40 Fat Emulsions, Intravenous Phase 4
41 Parenteral Nutrition Solutions Phase 4
42 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3
43 Soybean oil, phospholipid emulsion Phase 4
44 Adjuvants, Anesthesia Phase 4,Phase 2,Phase 3,Phase 1
45 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
46 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1
47 Analgesics, Opioid Phase 4,Phase 2,Phase 3,Phase 1
48 Anesthetics Phase 4,Phase 2,Phase 3,Phase 1
49 Anesthetics, General Phase 4,Phase 2,Phase 3,Phase 1
50 Anesthetics, Intravenous Phase 4,Phase 2,Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 200)
id Name Status NCT ID Phase
1 Multi-center Clinical Study of Early Antibios of Severe Acute Pancreatitis Unknown status NCT01992198 Phase 4
2 Comparative Study About the Impact of Two Oil Emulsions Administered Intravenously on Severe Acute Pancreatitis Unknown status NCT01376817 Phase 4
3 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
4 A Study to Determine if Antibiotics Prevent Infection in the Pancreas of Patients Where Part of the Pancreas Has Died Completed NCT00061438 Phase 4
5 Early Enteral Nutrition for Severe Acute Pancreatitis Completed NCT00995098 Phase 4
6 Enteral Nutrition in Acute Pancreatitis Completed NCT01965873 Phase 4
7 Activated Protein C in Severe Acute Pancreatitis Completed NCT01017107 Phase 4
8 The Correlations Between Early Enteral Nutrition and Intra-abdominal Pressure in Severe Acute Pancreatitis Completed NCT01507766 Phase 4
9 Acute Pancreatitis and Acute Fluid Collections Completed NCT00786929 Phase 4
10 Somatostatin, Octreotide, Pentoxyfilline in the Prevention of Post-ERCP Pancreatitis and Molecular Markers Completed NCT00222092 Phase 4
11 A Trial of 0.025 Wire Guided Cannulation Versus Current Practice 0.035 Wire Guided Cannulation Completed NCT01408264 Phase 4
12 UDCA for Symptomatic Gallstone Disease Completed NCT00161083 Phase 4
13 Nutritional and Metabolic Evaluation of a Tube Feeding Immune Enhancing Diet in ICU Patients Completed NCT00560157 Phase 4
14 Sitagliptin Therapy to Improve Outcomes After Islet Autotransplant Completed NCT01186562 Phase 4
15 Imipenem Prophylaxis in Patients With Acute Pancreatitis Recruiting NCT02897206 Phase 4
16 Treatment of Acute Pancreatitis With Ketorolac Recruiting NCT02885441 Phase 4
17 Epinephrine Sprayed on the Papilla for the Prevention of Post-ERCP Pancreatitis Recruiting NCT02839356 Phase 4
18 Timing of Indomethacin Administration for the Prevention of Post-ERCP Pancreatitis (PEP) Recruiting NCT02111707 Phase 4
19 Thiopurine Induced Pancreatitis in IBD Patients Recruiting NCT02281799 Phase 4
20 Anti-inflammatory Therapy to Improve Outcomes After TPIAT Recruiting NCT02713997 Phase 4
21 Dexmedetomidine Hydrochloride in the Prevention of Organ Failure Following Severe Acute Pancreatitis Not yet recruiting NCT02691598 Phase 4
22 Oral Resveratrol to Prevent Post-ERCP Pancreatitis Not yet recruiting NCT02947932 Phase 4
23 Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine Removal Not yet recruiting NCT03082469 Phase 4
24 COX-2 Inhibitor to Prevent Post-ERCP Pancreatitis Not yet recruiting NCT02964403 Phase 4
25 Ulinastatin in Severe Acute Pancreatitis Suspended NCT01132521 Phase 4
26 IHPOTOTAM : Induced HyPOthermia TO Treat Adult Meningitis Terminated NCT00774631 Phase 4
27 Study Comparing Early Laparoscopy With Active Observation in Acute Non-specific Abdominal Pain Terminated NCT01675466 Phase 4
28 Evaluation of Effect of Integrated Treatment by Traditional Chinese and Western Medicine for Severe Acute Pancreatitis Unknown status NCT00506337 Phase 2, Phase 3
29 Effect of Traditional Chinese Medicine on GI Function Recovery and Nutrition Support in SAP Unknown status NCT00508729 Phase 2, Phase 3
30 Efficacy of Administration of Somatostatin in the Prevention of Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis Unknown status NCT01060826 Phase 3
31 Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X] Unknown status NCT01109498 Phase 2, Phase 3
32 A Prospective Validation Study of Albumin Kinetics With Tracer 123 I-HSA Unknown status NCT01686776 Phase 3
33 EUROPAC-2 - Pain Treatment of Hereditary and Idiopathic Pancreatitis Unknown status NCT00142233 Phase 2, Phase 3
34 The Effect of Ulinastatin on Bronchoalveolar Lavage Fluid of Inflammatory Factors in Patients With Ventilator-associated Pneumonia Unknown status NCT01865266 Phase 2, Phase 3
35 MIld to MOderate Acute Pancreatitis: Early naSogastric Tube Feeding Compared With pAncreas Rest (MIMOSA) Completed NCT01128478 Phase 2, Phase 3
36 Indomethacin Decreases Post-ERCP Pancreatitis Completed NCT02110810 Phase 3
37 Use of Streptokinase for Enhancement of Percutaneous Drainage of Pancreatic Necrosis Completed NCT01977118 Phase 2, Phase 3
38 Does Glyceryl Nitrate Prevent Post-Endoscopic Retrograde Cholangiopancreaticography (ERCP) Pancreatitis? Completed NCT00121901 Phase 3
39 Effects of Delayed Enteral Nutrition on Inflammatory Responses and Immune Function Competence in Critically Ill Patients With Prolonged Fasting Completed NCT01834430 Phase 3
40 A Study of Dulaglutide (LY2189265) in Participants With Type II Diabetes Completed NCT02152371 Phase 3
41 Study of How Dulaglutide Compares to Placebo in Participants With Type 2 Diabetes Who Are Also on Sulfonylurea Therapy (AWARD-8) Completed NCT01769378 Phase 3
42 A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes Completed NCT01624259 Phase 3
43 Comparison of Endoscopic Sphincterotomy Plus Large-balloon Dilatation and Conventional Treatment for Large CBD Stones Completed NCT02592811 Phase 3
44 A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus Completed NCT02597049 Phase 3
45 Safety and Efficacy of Synthetic Human Secretin-Enhanced MRCP in Subjects With Abnormalities of the Pancreas Completed NCT00660335 Phase 3
46 ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia Intermittent Versus Continuous PEG Asparaginase Completed NCT00819351 Phase 3
47 Epidural Anesthesia in Acute Pancreatitis Recruiting NCT02617199 Phase 2, Phase 3
48 A Randomized Controlled Pilot Trial of Indomethacin in Acute Pancreatitis Recruiting NCT02692391 Phase 3
49 Fluid Resuscitation in Acute Pancreatitis Recruiting NCT02709044 Phase 2, Phase 3
50 Lactated Ringers With or Without Rectal Indomethacin to Prevent Post-ERCP Pancreatitis Recruiting NCT02641561 Phase 3

Search NIH Clinical Center for Acute Pancreatitis

Genetic Tests for Acute Pancreatitis

Genetic tests related to Acute Pancreatitis:

id Genetic test Affiliating Genes
1 Acute Pancreatitis 29

Anatomical Context for Acute Pancreatitis

MalaCards organs/tissues related to Acute Pancreatitis:

39
Pancreas, Lung, Neutrophil, Liver, Monocytes, Testes, Kidney

Publications for Acute Pancreatitis

Articles related to Acute Pancreatitis:

(show top 50) (show all 1661)
id Title Authors Year
1
Therapeutic plasmapheresis for hypertriglyceridemia-associated acute pancreatitis: case series and review of the literature. ( 28507728 )
2017
2
The Role of Gut-brain Axis in Regulating Glucose Metabolism After Acute Pancreatitis. ( 28055028 )
2017
3
Circulating microRNA 216 as a Marker for the Early Identification of Severe Acute Pancreatitis. ( 28183420 )
2017
4
The Diagnostic Usefulness of Serum Total Bile Acid Concentrations in the Early Phase of Acute Pancreatitis of Varied Etiologies. ( 28067818 )
2017
5
CTRC gene polymorphism (p.G60=; c.180 Ca88>a88T) in acute pancreatitis. ( 28095786 )
2017
6
Abdominal paracentesis drainage improves tolerance of enteral nutrition in acute pancreatitis: a randomized controlled trial. ( 28050922 )
2017
7
A Rare Cause of Recurrent Acute Pancreatitis in a Child: Isovaleric Acidemia with Novel Mutation. ( 28401058 )
2017
8
Intramural gastric hematoma in the context of an acute pancreatitis. ( 28071060 )
2017
9
Thrombopoietin as Early Biomarker of Disease Severity in Patients With Acute Pancreatitis. ( 28079612 )
2017
10
Hypertriglyceridemia, an important and independent risk factor for acute pancreatitis in patients with type 2 diabetes mellitus. ( 28450786 )
2017
11
'Treat the Cause': the NCEPOD report on acute pancreatitis. ( 28067554 )
2017
12
The Value of Secretin-Enhanced MRCP in Patients With Recurrent Acute Pancreatitis. ( 27824485 )
2017
13
Development of a novel model of hypertriglyceridemic acute pancreatitis in mice. ( 28079184 )
2017
14
Epidemiology and outcome of acute pancreatitis in end-stage renal disease dialysis patients: a 10-year national cohort study. ( 28088773 )
2017
15
Left Hepatic Artery Pseudoaneurysm Caused by Acute Pancreatitis. ( 28068658 )
2017
16
Disseminated Intravascular Coagulation on Admission Predicts Complications and Poor Prognosis of Acute Pancreatitis: Analysis of the Nationwide Epidemiological Survey in Japan. ( 28085757 )
2017
17
NF-I_B in acute pancreatitis: Mechanisms and therapeutic potential. ( 27282980 )
2016
18
Effect of Previous High Glutamine Infusion on Inflammatory Mediators and Mortality in an Acute Pancreatitis Model. ( 28070142 )
2016
19
Intestinal permeability and systemic endotoxemia in patients with acute pancreatitis. ( 27179282 )
2016
20
Clinical features and treatment of hypertriglyceridemia-induced acute pancreatitis during pregnancy: A retrospective study. ( 26946248 )
2016
21
Scrub typhus masquerading as acute pancreatitis. ( 27161204 )
2016
22
A paediatric systemic lupus erythematosus patient presenting with acute pancreatitis: a rare case. ( 28053686 )
2016
23
Microscopic polyangiitis with crescentic glomerulonephritis initially presenting as acute pancreatitis. ( 26864299 )
2016
24
Novel mutations in the GPIHBP1 gene identified in 2 patients with recurrent acute pancreatitis. ( 26892125 )
2016
25
Hiatus Hernia: A Rare Cause of Acute Pancreatitis. ( 27066077 )
2016
26
An Unusual Cause of Recurrent Acute Pancreatitis. ( 26658042 )
2016
27
Recognition and Importance of New Definitions of Peripancreatic Fluid Collections in Managing Patients with Acute Pancreatitis. ( 27216496 )
2016
28
Early nasogastric feeding versus parenteral nutrition in severe acute pancreatitis: A retrospective study. ( 28083056 )
2016
29
Acute Pancreatitis and Gastroduodenal Intussusception Induced by an Underlying Gastric Gastrointestinal Stromal Tumor: A Case Report. ( 27104028 )
2016
30
Pathophysiological mechanisms in acute pancreatitis: Current understanding. ( 27206712 )
2016
31
Ansa pancreatica as a predisposing factor for recurrent acute pancreatitis. ( 27833385 )
2016
32
The role of Card9 overexpression in peripheral blood mononuclear cells from patients with aseptic acute pancreatitis. ( 26893103 )
2016
33
Effect of ceramide-1-phosphate transfer protein on intestinal bacterial translocation in severe acute pancreatitis. ( 27637474 )
2016
34
Bleeding due to acquired hemophilia A in acute pancreatitis: a case report. ( 26743559 )
2016
35
Cardiac tamponade, an unusual complication of acute pancreatitis. ( 26969361 )
2016
36
Protective Effects of Emodin-Induced Neutrophil Apoptosis via the Ca(2+)-Caspase 12 Pathway against SIRS in Rats with Severe Acute Pancreatitis. ( 28078280 )
2016
37
Recurrent acute pancreatitis in bowel malrotation. ( 27906430 )
2016
38
Case-fatality from acute pancreatitis is decreasing but its population mortality shows little change. ( 27161172 )
2016
39
Lipid metabolism in patients with chronic hyperglycemia after an episode of acute pancreatitis. ( 28065464 )
2016
40
Antibiotic use in acute pancreatitis: An audit of current practice in a tertiary centre. ( 27613614 )
2016
41
Up-regulation of Tight-Junction Proteins by p38 Mitogen-Activated Protein Kinase/p53 Inhibition Leads to a Reduction of Injury to the Intestinal Mucosal Barrier in Severe Acute Pancreatitis. ( 27171513 )
2016
42
Severe hypertriglyceridemia and factors associated with acute pancreatitis in an integrated health care system. ( 27578119 )
2016
43
Pancreatic panniculitis preceding acute pancreatitis and subsequent detection of an intraductal papillary mucinous neoplasm: A case report. ( 27408933 )
2016
44
Combined Analysis of Three Large Interventional Trials With Gliptins Indicates Increased Incidence of Acute Pancreatitis in Patients With Type 2 Diabetes. ( 27659407 )
2016
45
A rare case report on recurrent acute pancreatitis secondary to primary hyperparathyroidism. ( 27728265 )
2016
46
Acute pancreatitis-induced thrombotic thrombocytopenic purpura with recurrent acute pancreatitis. ( 26905311 )
2016
47
Revised Atlanta Classification for Acute Pancreatitis: A Pictorial Essay. ( 27163588 )
2016
48
4-Phenylbutyric Acid Attenuates Pancreatic Beta-Cell Injury in Rats with Experimental Severe Acute Pancreatitis. ( 27656209 )
2016
49
Polypharmacy and risk of acute pancreatitis. ( 27651204 )
2016
50
Hypertriglyceridemia-induced Acute Pancreatitis. ( 27876326 )
2016

Variations for Acute Pancreatitis

Expression for Acute Pancreatitis

Search GEO for disease gene expression data for Acute Pancreatitis.

Pathways for Acute Pancreatitis

GO Terms for Acute Pancreatitis

Cellular components related to Acute Pancreatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.89 CCK CPB1 CRP CTSB CXCL8 ELANE
2 extracellular space GO:0005615 9.55 CCK CPB1 CRP CTSB CXCL8 ELANE
3 secretory granule GO:0030141 9.33 ELANE MPO PLA2G2A

Biological processes related to Acute Pancreatitis according to GeneCards Suite gene sharing:

(show all 17)
id Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.81 ELANE IL10 IL6 MPO
2 inflammatory response GO:0006954 9.73 CRP CXCL8 IL10 IL18 IL6 REG3A
3 defense response to Gram-positive bacterium GO:0050830 9.72 CRP IL6 PLA2G2A
4 positive regulation of smooth muscle cell proliferation GO:0048661 9.67 ELANE IL18 IL6
5 positive regulation of inflammatory response GO:0050729 9.65 IL18 LPL PLA2G2A
6 antimicrobial humoral response GO:0019730 9.63 ELANE PLA2G2A REG3A
7 lipid catabolic process GO:0016042 9.62 LPL PLA2G2A PLA2G6 PNLIP
8 acute-phase response GO:0006953 9.58 CRP IL6 REG3A
9 low-density lipoprotein particle remodeling GO:0034374 9.57 MPO PLA2G2A
10 response to molecule of bacterial origin GO:0002237 9.56 CXCL8 IL10
11 negative regulation of lipid storage GO:0010888 9.54 CRP IL6
12 positive regulation of T-helper 2 cell differentiation GO:0045630 9.52 IL18 IL6
13 type 2 immune response GO:0042092 9.43 IL10 IL18
14 negative regulation of chemokine biosynthetic process GO:0045079 9.37 ELANE IL6
15 negative regulation of growth of symbiont in host GO:0044130 9.33 ELANE IL10 MPO
16 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.13 IL18 LPL PLA2G2A
17 response to yeast GO:0001878 8.8 ELANE IL6 MPO

Molecular functions related to Acute Pancreatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.56 CPB1 CTSB ELANE LPL PLA2G2A PLA2G6
2 cytokine activity GO:0005125 8.92 CXCL8 IL10 IL18 IL6

Sources for Acute Pancreatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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