MCID: ACT040
MIFTS: 32

Acute Poststreptococcal Glomerulonephritis malady

Category: Nephrological diseases

Aliases & Classifications for Acute Poststreptococcal Glomerulonephritis

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Aliases & Descriptions for Acute Poststreptococcal Glomerulonephritis:

Name: Acute Poststreptococcal Glomerulonephritis 11 50 13
Acute Post-Streptococcal Glomerulonephritis 68
 
Post-Streptococcal Glomerulonephritis 11

Classifications:



External Ids:

Disease Ontology11 DOID:14064
SNOMED-CT62 68544003
NCIt45 C35443

Summaries for Acute Poststreptococcal Glomerulonephritis

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MalaCards based summary: Acute Poststreptococcal Glomerulonephritis, also known as acute post-streptococcal glomerulonephritis, is related to acute proliferative glomerulonephritis and glomerulonephritis. An important gene associated with Acute Poststreptococcal Glomerulonephritis is CFP (Complement Factor Properdin), and among its related pathways are Endothelins and Endothelin Pathways. Affiliated tissues include monocytes, skin and brain, and related mouse phenotypes are renal/urinary system and homeostasis/metabolism.

Related Diseases for Acute Poststreptococcal Glomerulonephritis

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Diseases related to Acute Poststreptococcal Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 60)
idRelated DiseaseScoreTop Affiliating Genes
1acute proliferative glomerulonephritis11.2
2glomerulonephritis10.8
3rheumatic fever10.2
4miller-dieker lissencephaly syndrome10.2PLG, SERPINF2
5influenza10.2PLG, SERPINF2
6angiokeratoma10.2CD79A, CFP
7mixed hepatoblastoma10.2PLG, SERPINF2
8chronic fatigue syndrome10.2PLG, SERPINF2
9eastern equine encephalitis10.2EDN1, NPPA
10sezary's disease10.2PLG, SERPINF2
11myopia10.2EDN1, NPPA
12dextrocardia10.1CD79A, PLG
13iida kannari syndrome10.1EDN1, NPPA
14nephrosclerosis10.1CD79A, CFP
15lymphadenitis10.1EDN1, NPPA
16intravascular angioleiomyoma10.1CD79A, PLG
17bronchiolitis10.1CD79A, CFP
18supratentorial primitive neuroectodermal tumor10.1CD79A, EDN1
19pleural disease10.1CFP, SERPINF2
20high-grade dysplasia in patients with barrett esophagus10.1EDN1, NPPA
21pregnancy loss, recurrent 110.1PLG, SERPINF2
22aids dementia complex10.1CFP, SERPINF2
23cholera10.1CD79A, SERPINF2
24ureteral lymphoma10.0CD79A, CFP
25mixed germ cell-sex cord neoplasm10.0CD79A, CFP
26impetigo10.0
27adenocarcinoma10.0EDN1, EDNRB
28epstein-barr virus hepatitis10.0NPPA, PLG, SERPINF2
29pyelonephritis10.0EDN1, NPPA
30paranasal sinus sarcoma10.0CD79A, EDN1
31adult t-cell leukemia10.0EDN1, NPPA, SERPINF2
32lymphoblastic lymphoma10.0EDN1, NPPA, SERPINF2
33zellweger syndrome10.0EDN1, EDNRB
34rheumatoid arthritis9.9
35arthritis9.9
36purpura9.9
37hypertensive encephalopathy9.9
38encephalopathy9.9
39diffuse alveolar hemorrhage9.9
40wound botulism9.9CD79A, EDNRB
41herpes simplex9.9EDN1, NPPA
42hypertension, essential9.8EDN1, EDNRB, NPPA
43myocardial infarction9.8EDN1, NPPA, PLG, SERPINF2
44cerebral hemorrhage9.8
45thrombocytopenia9.8
46interstitial nephritis9.8
47nephrotic syndrome9.8
48hemolytic-uremic syndrome9.8
49bardet-biedl syndrome9.8
50pharyngitis9.8

Graphical network of the top 20 diseases related to Acute Poststreptococcal Glomerulonephritis:



Diseases related to acute poststreptococcal glomerulonephritis

Symptoms & Phenotypes for Acute Poststreptococcal Glomerulonephritis

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MGI Mouse Phenotypes related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.1CD79A, EDN1, EDNRB, NPPA, PLG
2MP:00053767.6CD79A, CFP, EDN1, EDNRB, NPPA, PLG

Drugs & Therapeutics for Acute Poststreptococcal Glomerulonephritis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Hospital Based Incidence of Group A Streptococcal Disease in FijiCompletedNCT00264771

Search NIH Clinical Center for Acute Poststreptococcal Glomerulonephritis

Genetic Tests for Acute Poststreptococcal Glomerulonephritis

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Anatomical Context for Acute Poststreptococcal Glomerulonephritis

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MalaCards organs/tissues related to Acute Poststreptococcal Glomerulonephritis:

36
Monocytes, Skin, Brain, Spleen

Publications for Acute Poststreptococcal Glomerulonephritis

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Articles related to Acute Poststreptococcal Glomerulonephritis:

(show top 50)    (show all 129)
idTitleAuthorsYear
1
Acute poststreptococcal glomerulonephritis and acute rheumatic fever: An uncommon coincidence. (27625530)
2016
2
Acute poststreptococcal glomerulonephritis: the most common acute glomerulonephritis. (25554106)
2015
3
IgA-dominant acute poststreptococcal glomerulonephritis with concomitant rheumatic fever successfully treated with steroids: a case report. (26718763)
2015
4
Diffuse alveolar hemorrhage in a patient with acute poststreptococcal glomerulonephritis caused by impetigo. (25876581)
2015
5
Diffuse alveolar hemorrhage as a presentation of acute poststreptococcal glomerulonephritis. (24927907)
2014
6
Acute poststreptococcal glomerulonephritis with acute interstitial nephritis related to streptococcal pyrogenic exotoxin B. (26064502)
2013
7
Acute poststreptococcal glomerulonephritis: a manifestation of immune reconstitution inflammatory syndrome. (22891230)
2012
8
Acute reversible changes of brachial-ankle pulse wave velocity in children with acute poststreptococcal glomerulonephritis. (20640906)
2011
9
Unfavorable outcome in a child with megaureter-megacystis syndrome complicated by mild acute poststreptococcal glomerulonephritis. (21166952)
2010
10
Localization of nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis. (20708459)
2010
11
Evidence-based treatment limitations prevent any therapeutic recommendation for acute poststreptococcal glomerulonephritis in children. (20357732)
2010
12
Elevated plasma levels of N-terminal pro-brain natriuretic peptide in children with acute poststreptococcal glomerulonephritis. (19346734)
2009
13
Elevated expressions of 15-lipoxygenase and lipoxin A4 in children with acute poststreptococcal glomerulonephritis. (19095947)
2009
14
Acute poststreptococcal glomerulonephritis superimposed on IgA nephropathy. (18793531)
2008
15
Acute poststreptococcal glomerulonephritis: an update. (18332711)
2008
16
Elevated urinary plasmin activity resistant to alpha2-antiplasmin in acute poststreptococcal glomerulonephritis. (18223261)
2008
17
Sequence and expression of NAPlr is conserved among group A streptococci isolated from patients with acute poststreptococcal glomerulonephritis (APSGN) and non-APSGN. (17557271)
2007
18
Nephritogenic antigen for acute poststreptococcal glomerulonephritis. (16518356)
2006
19
Antibodies against four proteins from a Streptococcus pyogenes serotype M1 strain and levels of circulating mannan-binding lectin in acute poststreptococcal glomerulonephritis. (16508336)
2006
20
Glomerular plasmin-like activity in relation to nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis. (15574512)
2005
21
An adult with acute poststreptococcal glomerulonephritis complicated by hemolytic uremic syndrome and nephrotic syndrome. (16183409)
2005
22
Nephritis-associated plasmin receptor and acute poststreptococcal glomerulonephritis: characterization of the antigen and associated immune response. (15213266)
2004
23
Monocyte chemoattractant protein-1 and interleukin-8 levels in children with acute poststreptococcal glomerulonephritis. (15206029)
2004
24
Endothelin-1 in children with acute poststreptococcal glomerulonephritis and hypertension. (12654066)
2003
25
Thrombocytopenia during the course of acute poststreptococcal glomerulonephritis. (12921303)
2003
26
Acute poststreptococcal glomerulonephritis mimicking Henoch-SchAPnlein purpura. (12572934)
2003
27
Acute poststreptococcal glomerulonephritis and acute rheumatic fever in the same patient: a case report and review of the literature. (12967898)
2003
28
Acute poststreptococcal glomerulonephritis in a child with Bardet-Biedl syndrome. (11793138)
2002
29
Another case of acute poststreptococcal glomerulonephritis with recurrence. (12162274)
2002
30
Acute poststreptococcal glomerulonephritis: public health implications of recent clusters in New South Wales and epidemiology of hospital admissions. (11467793)
2001
31
Recurrence of acute poststreptococcal glomerulonephritis. (11465811)
2001
32
Prognosis of acute poststreptococcal glomerulonephritis (APSGN) is excellent in children, when adequately diagnosed. (11472580)
2001
33
Acute poststreptococcal glomerulonephritis following circumcision. (11149125)
2000
34
The potential role for nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis. (10816380)
2000
35
Acute poststreptococcal glomerulonephritis associated with thrombotic microangiopathy in an adult. (10968697)
2000
36
Renal function during and after childhood acute poststreptococcal glomerulonephritis. (10603146)
1999
37
Frequency of microscopic hematuria in acute poststreptococcal glomerulonephritis. (10353421)
1999
38
Evaluating the use of penicillin to control outbreaks of acute poststreptococcal glomerulonephritis. (10223684)
1999
39
Anticardiolipin antibodies in acute poststreptococcal glomerulonephritis and streptococcal impetigo. (10461035)
1999
40
Acute poststreptococcal glomerulonephritis presenting with hemoptysis. (9686966)
1998
41
C3 mesangial proliferative glomerulonephritis--an evaluation of acute poststreptococcal glomerulonephritis? (9518184)
1997
42
Renal functional reserve after acute poststreptococcal glomerulonephritis. (9260248)
1997
43
Acute poststreptococcal glomerulonephritis in children. (9331614)
1997
44
Searching for acute poststreptococcal glomerulonephritis-associated Streptococcus pyogenes in Australian aboriginal communities. (9331610)
1997
45
Asymptomatic acute poststreptococcal glomerulonephritis following upper respiratory tract infections caused by Group A streptococci. (8953117)
1996
46
An experimental model for acute poststreptococcal glomerulonephritis in mice. (8982244)
1996
47
Myocardial dysfunction in a 23-month child with acute poststreptococcal glomerulonephritis. (7793601)
1995
48
Renal hydatid cyst detected in a child during the course of acute poststreptococcal glomerulonephritis. (7723915)
1995
49
Cell-mediated immune response in acute poststreptococcal glomerulonephritis. (8022104)
1994
50
Cranial computed tomographic findings in a patient with hypertensive encephalopathy in acute poststreptococcal glomerulonephritis. (7825239)
1994

Variations for Acute Poststreptococcal Glomerulonephritis

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Expression for genes affiliated with Acute Poststreptococcal Glomerulonephritis

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Search GEO for disease gene expression data for Acute Poststreptococcal Glomerulonephritis.

Pathways for genes affiliated with Acute Poststreptococcal Glomerulonephritis

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Pathways related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.4EDN1, EDNRB
29.4EDN1, EDNRB
39.4EDN1, EDNRB
49.3PLG, SERPINF2
5
Show member pathways
8.8C4BPA, PLG, SERPINF2

GO Terms for genes affiliated with Acute Poststreptococcal Glomerulonephritis

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Cellular components related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:00725629.5C4BPA, PLG, SERPINF2
2platelet alpha granule lumenGO:00310939.3PLG, SERPINF2
3extracellular regionGO:00055768.0C4BPA, CFP, EDN1, NPPA, PLG, SERPINF2
4extracellular spaceGO:00056157.8C4BPA, CFP, EDN1, NPPA, PLG, SERPINF2

Biological processes related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1calcium-mediated signalingGO:001972210.1EDN1, EDNRB
2epithelial fluid transportGO:004204510.1EDN1, EDNRB
3negative regulation of cellular protein metabolic processGO:003226910.1EDN1, EDNRB
4positive regulation of renal sodium excretionGO:003581510.1EDN1, EDNRB
5positive regulation of urine volumeGO:003581010.0EDN1, EDNRB
6regulation of pHGO:000688510.0EDN1, EDNRB
7regulation of sensory perception of painGO:005193010.0EDN1, EDNRB
8positive regulation of heart rateGO:001046010.0EDN1, NPPA
9fibrinolysisGO:00427309.9PLG, SERPINF2
10negative regulation of fibrinolysisGO:00519189.9PLG, SERPINF2
11regulation of blood vessel sizeGO:00508809.9EDN1, NPPA
12response to muscle stretchGO:00359949.8EDN1, NPPA
13sensory perception of painGO:00192339.8EDN1, EDNRB
14blood vessel morphogenesisGO:00485149.7EDN1, SERPINF2
15positive regulation of smooth muscle cell proliferationGO:00486619.6EDN1, SERPINF2
16cell surface receptor signaling pathwayGO:00071669.6CD79A, EDN1, EDNRB
17vasoconstrictionGO:00423109.5EDN1, EDNRB
18regulation of blood pressureGO:00082179.5EDN1, EDNRB, NPPA
19vein smooth muscle contractionGO:00148269.4EDN1, EDNRB

Molecular functions related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor bindingGO:00051029.0EDN1, NPPA, PLG

Sources for Acute Poststreptococcal Glomerulonephritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet