MCID: ACT040
MIFTS: 32

Acute Poststreptococcal Glomerulonephritis malady

Category: Nephrological diseases

Aliases & Classifications for Acute Poststreptococcal Glomerulonephritis

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Aliases & Descriptions for Acute Poststreptococcal Glomerulonephritis:

Name: Acute Poststreptococcal Glomerulonephritis 11 50 13
Acute Post-Streptococcal Glomerulonephritis 68
 
Post-Streptococcal Glomerulonephritis 11

Classifications:



External Ids:

Disease Ontology11 DOID:14064
SNOMED-CT62 68544003
NCIt45 C35443

Summaries for Acute Poststreptococcal Glomerulonephritis

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MalaCards based summary: Acute Poststreptococcal Glomerulonephritis, also known as acute post-streptococcal glomerulonephritis, is related to mesangial proliferative glomerulonephritis and acute proliferative glomerulonephritis. An important gene associated with Acute Poststreptococcal Glomerulonephritis is CFP (Complement Factor Properdin), and among its related pathways are Endothelins and Endothelin. Affiliated tissues include monocytes, skin and brain, and related mouse phenotypes are renal/urinary system and homeostasis/metabolism.

Related Diseases for Acute Poststreptococcal Glomerulonephritis

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Diseases related to Acute Poststreptococcal Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idRelated DiseaseScoreTop Affiliating Genes
1mesangial proliferative glomerulonephritis30.0CD79A, CFP
2acute proliferative glomerulonephritis11.2
3glomerulonephritis10.8
4silver-russell syndrome due to 7p11.2p13 microduplication10.2EDN1, NPPA
5substance-induced psychosis10.2CD79A, PLG
6rheumatic fever10.2
7lacrimal gland carcinoma10.2CD79A, CFP
8chylocele of tunica vaginalis10.2EDN1, NPPA
9gait apraxia10.2CD79A, PLG
10ariboflavinosis10.2PLG, SERPINF2
11cerebellopontine angle primitive neuroectodermal10.2CD79A, EDN1
12cavernous hemangioma of face10.2PLG, SERPINF2
13mental depression10.1EDN1, NPPA
14sporotrichosis10.1CD79A, CFP
15tinea barbae10.1CD79A, PLG
16penile disease10.1CFP, SERPINF2
17hodgkin's lymphoma, lymphocytic-histiocytic predominance10.0EDN1, NPPA
18impetigo10.0
19extrahepatic cholestasis10.0CD79A, EDN1
20thrombophilia due to activated protein c resistance9.9PLG, SERPINF2
21iga glomerulonephritis9.9EDN1, EDNRB
22rheumatoid arthritis9.9
23arthritis9.9
24purpura9.9
25hypertensive encephalopathy9.9
26encephalopathy9.9
27diffuse alveolar hemorrhage9.9
28spinal canal and spinal cord meningioma9.9EDN1, NPPA
29craniosynostosis9.9EDN1, NPPA
30liver fibroma9.8CD79A, EDNRB
31larynx carcinoma in situ9.8EDN1, EDNRB
32adult respiratory distress syndrome9.8EDN1, PLG, SERPINF2
33cerebral hemorrhage9.8
34thrombocytopenia9.8
35interstitial nephritis9.8
36hemolytic-uremic syndrome9.8
37bardet-biedl syndrome9.8
38pharyngitis9.8
39membranoproliferative glomerulonephritis9.8
40cerebritis9.8
41uremia9.8
42rapidly progressive glomerulonephritis9.8
43proliferative glomerulonephritis9.8
44pneumonia9.8
45sickle cell disease9.8
46lujo hemorrhagic fever9.7NPPA, PLG, SERPINF2
47lubani-al saleh-teebi syndrome9.5EDN1, EDNRB, NPPA
48rectum leiomyosarcoma9.5CD79A, EDNRB
49hypertension, essential9.4EDN1, EDNRB, NPPA
50myocardial infarction9.3EDN1, NPPA, PLG, SERPINF2

Graphical network of the top 20 diseases related to Acute Poststreptococcal Glomerulonephritis:



Diseases related to acute poststreptococcal glomerulonephritis

Symptoms & Phenotypes for Acute Poststreptococcal Glomerulonephritis

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MGI Mouse Phenotypes related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053677.9CD79A, EDN1, EDNRB, NPPA, PLG
2MP:00053767.7CD79A, CFP, EDN1, EDNRB, NPPA, PLG

Drugs & Therapeutics for Acute Poststreptococcal Glomerulonephritis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Hospital Based Incidence of Group A Streptococcal Disease in FijiCompletedNCT00264771

Search NIH Clinical Center for Acute Poststreptococcal Glomerulonephritis

Genetic Tests for Acute Poststreptococcal Glomerulonephritis

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Anatomical Context for Acute Poststreptococcal Glomerulonephritis

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MalaCards organs/tissues related to Acute Poststreptococcal Glomerulonephritis:

36
Monocytes, Skin, Brain, Spleen

Publications for Acute Poststreptococcal Glomerulonephritis

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Articles related to Acute Poststreptococcal Glomerulonephritis:

(show top 50)    (show all 129)
idTitleAuthorsYear
1
Acute poststreptococcal glomerulonephritis and acute rheumatic fever: An uncommon coincidence. (27625530)
2016
2
Diffuse alveolar hemorrhage in a patient with acute poststreptococcal glomerulonephritis caused by impetigo. (25876581)
2015
3
IgA-dominant acute poststreptococcal glomerulonephritis with concomitant rheumatic fever successfully treated with steroids: a case report. (26718763)
2015
4
Acute poststreptococcal glomerulonephritis: the most common acute glomerulonephritis. (25554106)
2015
5
Diffuse alveolar hemorrhage as a presentation of acute poststreptococcal glomerulonephritis. (24927907)
2014
6
Acute poststreptococcal glomerulonephritis with acute interstitial nephritis related to streptococcal pyrogenic exotoxin B. (26064502)
2013
7
Acute poststreptococcal glomerulonephritis: a manifestation of immune reconstitution inflammatory syndrome. (22891230)
2012
8
Acute reversible changes of brachial-ankle pulse wave velocity in children with acute poststreptococcal glomerulonephritis. (20640906)
2011
9
Localization of nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis. (20708459)
2010
10
Unfavorable outcome in a child with megaureter-megacystis syndrome complicated by mild acute poststreptococcal glomerulonephritis. (21166952)
2010
11
Evidence-based treatment limitations prevent any therapeutic recommendation for acute poststreptococcal glomerulonephritis in children. (20357732)
2010
12
Elevated plasma levels of N-terminal pro-brain natriuretic peptide in children with acute poststreptococcal glomerulonephritis. (19346734)
2009
13
Elevated expressions of 15-lipoxygenase and lipoxin A4 in children with acute poststreptococcal glomerulonephritis. (19095947)
2009
14
Acute poststreptococcal glomerulonephritis: an update. (18332711)
2008
15
Acute poststreptococcal glomerulonephritis superimposed on IgA nephropathy. (18793531)
2008
16
Elevated urinary plasmin activity resistant to alpha2-antiplasmin in acute poststreptococcal glomerulonephritis. (18223261)
2008
17
Sequence and expression of NAPlr is conserved among group A streptococci isolated from patients with acute poststreptococcal glomerulonephritis (APSGN) and non-APSGN. (17557271)
2007
18
Nephritogenic antigen for acute poststreptococcal glomerulonephritis. (16518356)
2006
19
Antibodies against four proteins from a Streptococcus pyogenes serotype M1 strain and levels of circulating mannan-binding lectin in acute poststreptococcal glomerulonephritis. (16508336)
2006
20
An adult with acute poststreptococcal glomerulonephritis complicated by hemolytic uremic syndrome and nephrotic syndrome. (16183409)
2005
21
Glomerular plasmin-like activity in relation to nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis. (15574512)
2005
22
Monocyte chemoattractant protein-1 and interleukin-8 levels in children with acute poststreptococcal glomerulonephritis. (15206029)
2004
23
Nephritis-associated plasmin receptor and acute poststreptococcal glomerulonephritis: characterization of the antigen and associated immune response. (15213266)
2004
24
Acute poststreptococcal glomerulonephritis and acute rheumatic fever in the same patient: a case report and review of the literature. (12967898)
2003
25
Endothelin-1 in children with acute poststreptococcal glomerulonephritis and hypertension. (12654066)
2003
26
Thrombocytopenia during the course of acute poststreptococcal glomerulonephritis. (12921303)
2003
27
Acute poststreptococcal glomerulonephritis mimicking Henoch-SchAPnlein purpura. (12572934)
2003
28
Another case of acute poststreptococcal glomerulonephritis with recurrence. (12162274)
2002
29
Acute poststreptococcal glomerulonephritis in a child with Bardet-Biedl syndrome. (11793138)
2002
30
Acute poststreptococcal glomerulonephritis: public health implications of recent clusters in New South Wales and epidemiology of hospital admissions. (11467793)
2001
31
Prognosis of acute poststreptococcal glomerulonephritis (APSGN) is excellent in children, when adequately diagnosed. (11472580)
2001
32
Recurrence of acute poststreptococcal glomerulonephritis. (11465811)
2001
33
The potential role for nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis. (10816380)
2000
34
Acute poststreptococcal glomerulonephritis following circumcision. (11149125)
2000
35
Acute poststreptococcal glomerulonephritis associated with thrombotic microangiopathy in an adult. (10968697)
2000
36
Frequency of microscopic hematuria in acute poststreptococcal glomerulonephritis. (10353421)
1999
37
Evaluating the use of penicillin to control outbreaks of acute poststreptococcal glomerulonephritis. (10223684)
1999
38
Renal function during and after childhood acute poststreptococcal glomerulonephritis. (10603146)
1999
39
Anticardiolipin antibodies in acute poststreptococcal glomerulonephritis and streptococcal impetigo. (10461035)
1999
40
Acute poststreptococcal glomerulonephritis presenting with hemoptysis. (9686966)
1998
41
Searching for acute poststreptococcal glomerulonephritis-associated Streptococcus pyogenes in Australian aboriginal communities. (9331610)
1997
42
Acute poststreptococcal glomerulonephritis in children. (9331614)
1997
43
Renal functional reserve after acute poststreptococcal glomerulonephritis. (9260248)
1997
44
C3 mesangial proliferative glomerulonephritis--an evaluation of acute poststreptococcal glomerulonephritis? (9518184)
1997
45
Asymptomatic acute poststreptococcal glomerulonephritis following upper respiratory tract infections caused by Group A streptococci. (8953117)
1996
46
An experimental model for acute poststreptococcal glomerulonephritis in mice. (8982244)
1996
47
Renal hydatid cyst detected in a child during the course of acute poststreptococcal glomerulonephritis. (7723915)
1995
48
Myocardial dysfunction in a 23-month child with acute poststreptococcal glomerulonephritis. (7793601)
1995
49
Cell-mediated immune response in acute poststreptococcal glomerulonephritis. (8022104)
1994
50
Etiopathogenesis of acute poststreptococcal glomerulonephritis. (18583766)
1994

Variations for Acute Poststreptococcal Glomerulonephritis

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Expression for genes affiliated with Acute Poststreptococcal Glomerulonephritis

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Search GEO for disease gene expression data for Acute Poststreptococcal Glomerulonephritis.

Pathways for genes affiliated with Acute Poststreptococcal Glomerulonephritis

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GO Terms for genes affiliated with Acute Poststreptococcal Glomerulonephritis

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Cellular components related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:00725629.7C4BPA, PLG, SERPINF2
2platelet alpha granule lumenGO:00310939.5PLG, SERPINF2
3extracellular regionGO:00055768.0C4BPA, CFP, EDN1, NPPA, PLG, SERPINF2
4extracellular spaceGO:00056157.7C4BPA, CFP, EDN1, NPPA, PLG, SERPINF2

Biological processes related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1epithelial fluid transportGO:004204510.2EDN1, EDNRB
2negative regulation of cellular protein metabolic processGO:003226910.2EDN1, EDNRB
3positive regulation of renal sodium excretionGO:003581510.2EDN1, EDNRB
4positive regulation of urine volumeGO:003581010.2EDN1, EDNRB
5fibrinolysisGO:004273010.2PLG, SERPINF2
6negative regulation of fibrinolysisGO:005191810.2PLG, SERPINF2
7regulation of pHGO:000688510.1EDN1, EDNRB
8regulation of sensory perception of painGO:005193010.1EDN1, EDNRB
9blood vessel morphogenesisGO:004851410.1EDN1, SERPINF2
10regulation of complement activationGO:003044910.1C4BPA, CFP
11positive regulation of smooth muscle cell proliferationGO:004866110.0EDN1, SERPINF2
12sensory perception of painGO:00192339.9EDN1, EDNRB
13positive regulation of heart rateGO:00104609.8EDN1, NPPA
14vasoconstrictionGO:00423109.6EDN1, EDNRB
15response to muscle stretchGO:00359949.6EDN1, NPPA
16vein smooth muscle contractionGO:00148269.6EDN1, EDNRB
17regulation of blood pressureGO:00082179.3EDN1, EDNRB, NPPA

Molecular functions related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor bindingGO:00051028.7EDN1, NPPA, PLG

Sources for Acute Poststreptococcal Glomerulonephritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet