MCID: ACT040
MIFTS: 32

Acute Poststreptococcal Glomerulonephritis malady

Category: Nephrological diseases

Aliases & Classifications for Acute Poststreptococcal Glomerulonephritis

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Aliases & Descriptions for Acute Poststreptococcal Glomerulonephritis:

Name: Acute Poststreptococcal Glomerulonephritis 11 49 13
Acute Post-Streptococcal Glomerulonephritis 67
 
Post-Streptococcal Glomerulonephritis 11

Classifications:



External Ids:

Disease Ontology11 DOID:14064
SNOMED-CT61 68544003
NCIt44 C35443

Summaries for Acute Poststreptococcal Glomerulonephritis

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MalaCards based summary: Acute Poststreptococcal Glomerulonephritis, also known as acute post-streptococcal glomerulonephritis, is related to mesangial proliferative glomerulonephritis and acute proliferative glomerulonephritis. An important gene associated with Acute Poststreptococcal Glomerulonephritis is CFP (Complement Factor Properdin), and among its related pathways are Endothelins and Endothelin. Affiliated tissues include monocytes, skin and brain, and related mouse phenotypes are renal/urinary system and homeostasis/metabolism.

Related Diseases for Acute Poststreptococcal Glomerulonephritis

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Diseases related to Acute Poststreptococcal Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idRelated DiseaseScoreTop Affiliating Genes
1mesangial proliferative glomerulonephritis30.0CD79A, CFP
2acute proliferative glomerulonephritis11.2
3glomerulonephritis10.8
4silver-russell syndrome due to 7p11.2p13 microduplication10.2EDN1, NPPA
5substance-induced psychosis10.2CD79A, PLG
6rheumatic fever10.2
7lacrimal gland carcinoma10.2CD79A, CFP
8chylocele of tunica vaginalis10.2EDN1, NPPA
9gait apraxia10.2CD79A, PLG
10ariboflavinosis10.2PLG, SERPINF2
11cerebellopontine angle primitive neuroectodermal10.2CD79A, EDN1
12cavernous hemangioma of face10.2PLG, SERPINF2
13mental depression10.1EDN1, NPPA
14sporotrichosis10.1CD79A, CFP
15tinea barbae10.1CD79A, PLG
16penile disease10.1CFP, SERPINF2
17hodgkin's lymphoma, lymphocytic-histiocytic predominance10.0EDN1, NPPA
18impetigo10.0
19extrahepatic cholestasis10.0CD79A, EDN1
20thrombophilia due to activated protein c resistance9.9PLG, SERPINF2
21iga glomerulonephritis9.9EDN1, EDNRB
22rheumatoid arthritis9.9
23arthritis9.9
24purpura9.9
25hypertensive encephalopathy9.9
26encephalopathy9.9
27diffuse alveolar hemorrhage9.9
28spinal canal and spinal cord meningioma9.9EDN1, NPPA
29craniosynostosis9.9EDN1, NPPA
30liver fibroma9.8CD79A, EDNRB
31larynx carcinoma in situ9.8EDN1, EDNRB
32adult respiratory distress syndrome9.8EDN1, PLG, SERPINF2
33cerebral hemorrhage9.8
34thrombocytopenia9.8
35interstitial nephritis9.8
36hemolytic-uremic syndrome9.8
37bardet-biedl syndrome9.8
38pharyngitis9.8
39membranoproliferative glomerulonephritis9.8
40cerebritis9.8
41uremia9.8
42rapidly progressive glomerulonephritis9.8
43proliferative glomerulonephritis9.8
44pneumonia9.8
45sickle cell disease9.8
46lujo hemorrhagic fever9.7NPPA, PLG, SERPINF2
47lubani-al saleh-teebi syndrome9.5EDN1, EDNRB, NPPA
48rectum leiomyosarcoma9.5CD79A, EDNRB
49hypertension, essential9.4EDN1, EDNRB, NPPA
50myocardial infarction9.3EDN1, NPPA, PLG, SERPINF2

Graphical network of the top 20 diseases related to Acute Poststreptococcal Glomerulonephritis:



Diseases related to acute poststreptococcal glomerulonephritis

Symptoms for Acute Poststreptococcal Glomerulonephritis

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Drugs & Therapeutics for Acute Poststreptococcal Glomerulonephritis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Hospital Based Incidence of Group A Streptococcal Disease in FijiCompletedNCT00264771

Search NIH Clinical Center for Acute Poststreptococcal Glomerulonephritis

Genetic Tests for Acute Poststreptococcal Glomerulonephritis

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Anatomical Context for Acute Poststreptococcal Glomerulonephritis

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MalaCards organs/tissues related to Acute Poststreptococcal Glomerulonephritis:

35
Monocytes, Skin, Brain, Spleen

Animal Models for Acute Poststreptococcal Glomerulonephritis or affiliated genes

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MGI Mouse Phenotypes related to Acute Poststreptococcal Glomerulonephritis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053677.9CD79A, EDN1, EDNRB, NPPA, PLG
2MP:00053767.7CD79A, CFP, EDN1, EDNRB, NPPA, PLG

Publications for Acute Poststreptococcal Glomerulonephritis

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Articles related to Acute Poststreptococcal Glomerulonephritis:

(show top 50)    (show all 129)
idTitleAuthorsYear
1
Acute poststreptococcal glomerulonephritis and acute rheumatic fever: An uncommon coincidence. (27625530)
2016
2
Diffuse alveolar hemorrhage in a patient with acute poststreptococcal glomerulonephritis caused by impetigo. (25876581)
2015
3
IgA-dominant acute poststreptococcal glomerulonephritis with concomitant rheumatic fever successfully treated with steroids: a case report. (26718763)
2015
4
Localization of nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis. (20708459)
2010
5
Unfavorable outcome in a child with megaureter-megacystis syndrome complicated by mild acute poststreptococcal glomerulonephritis. (21166952)
2010
6
Acute poststreptococcal glomerulonephritis: an update. (18332711)
2008
7
Sequence and expression of NAPlr is conserved among group A streptococci isolated from patients with acute poststreptococcal glomerulonephritis (APSGN) and non-APSGN. (17557271)
2007
8
Nephritogenic antigen for acute poststreptococcal glomerulonephritis. (16518356)
2006
9
An adult with acute poststreptococcal glomerulonephritis complicated by hemolytic uremic syndrome and nephrotic syndrome. (16183409)
2005
10
Monocyte chemoattractant protein-1 and interleukin-8 levels in children with acute poststreptococcal glomerulonephritis. (15206029)
2004
11
Acute poststreptococcal glomerulonephritis and acute rheumatic fever in the same patient: a case report and review of the literature. (12967898)
2003
12
Another case of acute poststreptococcal glomerulonephritis with recurrence. (12162274)
2002
13
Acute poststreptococcal glomerulonephritis: public health implications of recent clusters in New South Wales and epidemiology of hospital admissions. (11467793)
2001
14
Prognosis of acute poststreptococcal glomerulonephritis (APSGN) is excellent in children, when adequately diagnosed. (11472580)
2001
15
Recurrence of acute poststreptococcal glomerulonephritis. (11465811)
2001
16
Frequency of microscopic hematuria in acute poststreptococcal glomerulonephritis. (10353421)
1999
17
Renal hydatid cyst detected in a child during the course of acute poststreptococcal glomerulonephritis. (7723915)
1995
18
Cell-mediated immune response in acute poststreptococcal glomerulonephritis. (8022104)
1994
19
Etiopathogenesis of acute poststreptococcal glomerulonephritis. (18583766)
1994
20
Cranial computed tomographic findings in a patient with hypertensive encephalopathy in acute poststreptococcal glomerulonephritis. (7825239)
1994
21
Significance of albuminuria in the follow-up of acute poststreptococcal glomerulonephritis. (8050204)
1994
22
Acute poststreptococcal glomerulonephritis followed by acute rheumatic carditis: an unusual case. (8251329)
1993
23
Wegener's granulomatosis and acute poststreptococcal glomerulonephritis. (8393551)
1993
24
Plasma atrial natriuretic peptide and endothelin levels in acute poststreptococcal glomerulonephritis. (1482636)
1992
25
Role of a streptococcal antigen in the pathogenesis of acute poststreptococcal glomerulonephritis. Characterization of the antigen and a proposed mechanism for the disease. (1578137)
1992
26
Plasma terminal complement complexes in acute poststreptococcal glomerulonephritis. (1996575)
1991
27
Acute poststreptococcal glomerulonephritis and acute rheumatic fever: occurrence in the same patient. (2253249)
1990
28
A case of acute poststreptococcal glomerulonephritis associated with cerebral hemorrhage. (3694896)
1987
29
Incidence of circulating immune complexes in patients with acute poststreptococcal glomerulonephritis and in patients with streptococcal impetigo. (3530567)
1986
30
Detection of IgG-rheumatoid factor in sera of patients with acute poststreptococcal glomerulonephritis and its relationship with circulating immunecomplexes. (3757314)
1986
31
Glomerular binding sites for peanut agglutinin in acute poststreptococcal glomerulonephritis. (3542320)
1986
32
Suppression of cellular reactivity to group A streptococcal antigens in patients with acute poststreptococcal glomerulonephritis. (6234370)
1984
33
Circulating immune complexes in patients with uncomplicated group A streptococcal pharyngitis and patients with acute poststreptococcal glomerulonephritis. (6340506)
1983
34
Epidemic of acute poststreptococcal glomerulonephritis in aboriginal communities. (6571580)
1983
35
Neuraminidase and free sialic acid levels in acute poststreptococcal glomerulonephritis. (7278916)
1981
36
Characterization of the glomerular antibody in acute poststreptococcal glomerulonephritis. (6965830)
1980
37
Acute poststreptococcal glomerulonephritis in Maracaibo. II: Studies on the incidence, nature, and significance of circulating anti-immunoglobulins. (314784)
1979
38
Complement components and complement activation in acute poststreptococcal glomerulonephritis. (106018)
1979
39
Ultrasonic appearance of acute poststreptococcal glomerulonephritis. (416050)
1978
40
Does acute poststreptococcal glomerulonephritis lead to chronic renal disease? (628417)
1978
41
Necrotizing arteritis in acute poststreptococcal glomerulonephritis: report of a recovered case. (17662)
1977
42
Immune deposits in the spleen of a patient with acute poststreptococcal glomerulonephritis (APSGN). (975639)
1976
43
Defective phagocyte adherence in acute poststreptococcal glomerulonephritis: clinical and laboratory observations. (978322)
1976
44
The fate of subepithelial deposits in acute poststreptococcal glomerulonephritis. (792564)
1976
45
Intravenous diazoxide in acute poststreptococcal glomerulonephritis. (1185352)
1975
46
Acute poststreptococcal glomerulonephritis. A retrospective study. (4752192)
1973
47
Editorial: Acute poststreptococcal glomerulonephritis. Mechanism and sequelae--attempts at a unifying concept. (4593114)
1972
48
A specific antigen and antibody in acute poststreptococcal glomerulonephritis. (4911994)
1969
49
Acute poststreptococcal glomerulonephritis presenting as hypertensive encephalopathy with minimal urinary abnormalities. (6018971)
1967
50
Acute poststreptococcal glomerulonephritis: immune deposit disease. (4159050)
1966

Variations for Acute Poststreptococcal Glomerulonephritis

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Expression for genes affiliated with Acute Poststreptococcal Glomerulonephritis

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Search GEO for disease gene expression data for Acute Poststreptococcal Glomerulonephritis.

Pathways for genes affiliated with Acute Poststreptococcal Glomerulonephritis

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GO Terms for genes affiliated with Acute Poststreptococcal Glomerulonephritis

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Cellular components related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:003109310.2PLG, SERPINF2
2blood microparticleGO:00725628.9C4BPA, PLG, SERPINF2
3extracellular regionGO:00055767.1C4BPA, CFP, EDN1, NPPA, PLG, SERPINF2
4extracellular spaceGO:00056156.9C4BPA, CFP, EDN1, NPPA, PLG, SERPINF2

Biological processes related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1vein smooth muscle contractionGO:001482610.2EDN1, EDNRB
2negative regulation of cellular protein metabolic processGO:003226910.2EDN1, EDNRB
3vasoconstrictionGO:004231010.0EDN1, EDNRB
4regulation of pHGO:00068859.9EDN1, EDNRB
5regulation of sensory perception of painGO:00519309.9EDN1, EDNRB
6fibrinolysisGO:00427309.8PLG, SERPINF2
7epithelial fluid transportGO:00420459.8EDN1, EDNRB
8negative regulation of fibrinolysisGO:00519189.8PLG, SERPINF2
9regulation of complement activationGO:00304499.8C4BPA, CFP
10sensory perception of painGO:00192339.7EDN1, EDNRB
11positive regulation of smooth muscle cell proliferationGO:00486619.7EDN1, SERPINF2
12positive regulation of heart rateGO:00104609.6EDN1, NPPA
13blood vessel morphogenesisGO:00485149.6EDN1, SERPINF2
14positive regulation of renal sodium excretionGO:00358159.6EDN1, EDNRB
15positive regulation of urine volumeGO:00358109.3EDN1, EDNRB
16response to muscle stretchGO:00359949.1EDN1, NPPA
17regulation of blood pressureGO:00082178.8EDN1, EDNRB, NPPA

Molecular functions related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor bindingGO:00051028.7EDN1, NPPA, PLG

Sources for Acute Poststreptococcal Glomerulonephritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet