MCID: ACT040
MIFTS: 32

Acute Poststreptococcal Glomerulonephritis malady

Categories: Nephrological diseases

Aliases & Classifications for Acute Poststreptococcal Glomerulonephritis

Aliases & Descriptions for Acute Poststreptococcal Glomerulonephritis:

Name: Acute Poststreptococcal Glomerulonephritis 12 52 14
Acute Post-Streptococcal Glomerulonephritis 69
Post-Streptococcal Glomerulonephritis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14064
NCIt 47 C35443
SNOMED-CT 64 68544003
UMLS 69 C0403414

Summaries for Acute Poststreptococcal Glomerulonephritis

MalaCards based summary : Acute Poststreptococcal Glomerulonephritis, also known as acute post-streptococcal glomerulonephritis, is related to acute proliferative glomerulonephritis and glomerulonephritis. An important gene associated with Acute Poststreptococcal Glomerulonephritis is CFP (Complement Factor Properdin), and among its related pathways/superpathways are Complement and coagulation cascades and Endothelins. Affiliated tissues include monocytes, skin and brain, and related phenotypes are homeostasis/metabolism and renal/urinary system

Related Diseases for Acute Poststreptococcal Glomerulonephritis

Diseases related to Acute Poststreptococcal Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
id Related Disease Score Top Affiliating Genes
1 acute proliferative glomerulonephritis 11.2
2 glomerulonephritis 10.8
3 rheumatic fever 10.2
4 miller-dieker lissencephaly syndrome 10.2 PLG SERPINF2
5 influenza 10.2 PLG SERPINF2
6 angiokeratoma 10.2 CD79A CFP
7 mixed hepatoblastoma 10.2 PLG SERPINF2
8 chronic fatigue syndrome 10.2 PLG SERPINF2
9 eastern equine encephalitis 10.2 EDN1 NPPA
10 sezary's disease 10.2 PLG SERPINF2
11 myopia 10.2 EDN1 NPPA
12 dextrocardia 10.1 CD79A PLG
13 iida kannari syndrome 10.1 EDN1 NPPA
14 nephrosclerosis 10.1 CD79A CFP
15 lymphadenitis 10.1 EDN1 NPPA
16 intravascular angioleiomyoma 10.1 CD79A PLG
17 bronchiolitis 10.1 CD79A CFP
18 supratentorial primitive neuroectodermal tumor 10.1 CD79A EDN1
19 pleural disease 10.1 CFP SERPINF2
20 high-grade dysplasia in patients with barrett esophagus 10.1 EDN1 NPPA
21 pregnancy loss, recurrent 1 10.1 PLG SERPINF2
22 aids dementia complex 10.1 CFP SERPINF2
23 cholera 10.1 CD79A SERPINF2
24 ureteral lymphoma 10.0 CD79A CFP
25 mixed germ cell-sex cord neoplasm 10.0 CD79A CFP
26 impetigo 10.0
27 adenocarcinoma 10.0 EDN1 EDNRB
28 epstein-barr virus hepatitis 10.0 NPPA PLG SERPINF2
29 pyelonephritis 10.0 EDN1 NPPA
30 paranasal sinus sarcoma 10.0 CD79A EDN1
31 adult t-cell leukemia 10.0 EDN1 NPPA SERPINF2
32 lymphoblastic lymphoma 10.0 EDN1 NPPA SERPINF2
33 zellweger syndrome 10.0 EDN1 EDNRB
34 hypertensive encephalopathy 9.9
35 encephalopathy 9.9
36 diffuse alveolar hemorrhage 9.9
37 purpura 9.9
38 rheumatoid arthritis 9.9
39 arthritis 9.9
40 wound botulism 9.9 CD79A EDNRB
41 herpes simplex 9.9 EDN1 NPPA
42 hypertension, essential 9.8 EDN1 EDNRB NPPA
43 myocardial infarction 9.8 EDN1 NPPA PLG SERPINF2
44 cerebral hemorrhage 9.8
45 mesangial proliferative glomerulonephritis 9.8
46 pneumonia 9.8
47 thrombocytopenia 9.8
48 interstitial nephritis 9.8
49 nephrotic syndrome 9.8
50 sickle cell disease 9.8

Graphical network of the top 20 diseases related to Acute Poststreptococcal Glomerulonephritis:



Diseases related to Acute Poststreptococcal Glomerulonephritis

Symptoms & Phenotypes for Acute Poststreptococcal Glomerulonephritis

MGI Mouse Phenotypes related to Acute Poststreptococcal Glomerulonephritis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.5 CD79A CFP EDN1 EDNRB NPPA PLG
2 renal/urinary system MP:0005367 9.02 CD79A EDN1 EDNRB NPPA PLG

Drugs & Therapeutics for Acute Poststreptococcal Glomerulonephritis

Interventional clinical trials:


id Name Status NCT ID Phase
1 Hospital Based Incidence of Group A Streptococcal Disease in Fiji Completed NCT00264771

Search NIH Clinical Center for Acute Poststreptococcal Glomerulonephritis

Genetic Tests for Acute Poststreptococcal Glomerulonephritis

Anatomical Context for Acute Poststreptococcal Glomerulonephritis

MalaCards organs/tissues related to Acute Poststreptococcal Glomerulonephritis:

39
Monocytes, Skin, Brain, Spleen

Publications for Acute Poststreptococcal Glomerulonephritis

Articles related to Acute Poststreptococcal Glomerulonephritis:

(show top 50) (show all 129)
id Title Authors Year
1
Acute poststreptococcal glomerulonephritis and acute rheumatic fever: An uncommon coincidence. ( 27625530 )
2016
2
Acute poststreptococcal glomerulonephritis: the most common acute glomerulonephritis. ( 25554106 )
2015
3
IgA-dominant acute poststreptococcal glomerulonephritis with concomitant rheumatic fever successfully treated with steroids: a case report. ( 26718763 )
2015
4
Diffuse alveolar hemorrhage in a patient with acute poststreptococcal glomerulonephritis caused by impetigo. ( 25876581 )
2015
5
Diffuse alveolar hemorrhage as a presentation of acute poststreptococcal glomerulonephritis. ( 24927907 )
2014
6
Acute poststreptococcal glomerulonephritis with acute interstitial nephritis related to streptococcal pyrogenic exotoxin B. ( 26064502 )
2013
7
Acute poststreptococcal glomerulonephritis: a manifestation of immune reconstitution inflammatory syndrome. ( 22891230 )
2012
8
Acute reversible changes of brachial-ankle pulse wave velocity in children with acute poststreptococcal glomerulonephritis. ( 20640906 )
2011
9
Unfavorable outcome in a child with megaureter-megacystis syndrome complicated by mild acute poststreptococcal glomerulonephritis. ( 21166952 )
2010
10
Localization of nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis. ( 20708459 )
2010
11
Evidence-based treatment limitations prevent any therapeutic recommendation for acute poststreptococcal glomerulonephritis in children. ( 20357732 )
2010
12
Elevated plasma levels of N-terminal pro-brain natriuretic peptide in children with acute poststreptococcal glomerulonephritis. ( 19346734 )
2009
13
Elevated expressions of 15-lipoxygenase and lipoxin A4 in children with acute poststreptococcal glomerulonephritis. ( 19095947 )
2009
14
Acute poststreptococcal glomerulonephritis superimposed on IgA nephropathy. ( 18793531 )
2008
15
Acute poststreptococcal glomerulonephritis: an update. ( 18332711 )
2008
16
Elevated urinary plasmin activity resistant to alpha2-antiplasmin in acute poststreptococcal glomerulonephritis. ( 18223261 )
2008
17
Sequence and expression of NAPlr is conserved among group A streptococci isolated from patients with acute poststreptococcal glomerulonephritis (APSGN) and non-APSGN. ( 17557271 )
2007
18
Nephritogenic antigen for acute poststreptococcal glomerulonephritis. ( 16518356 )
2006
19
Antibodies against four proteins from a Streptococcus pyogenes serotype M1 strain and levels of circulating mannan-binding lectin in acute poststreptococcal glomerulonephritis. ( 16508336 )
2006
20
Glomerular plasmin-like activity in relation to nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis. ( 15574512 )
2005
21
An adult with acute poststreptococcal glomerulonephritis complicated by hemolytic uremic syndrome and nephrotic syndrome. ( 16183409 )
2005
22
Nephritis-associated plasmin receptor and acute poststreptococcal glomerulonephritis: characterization of the antigen and associated immune response. ( 15213266 )
2004
23
Monocyte chemoattractant protein-1 and interleukin-8 levels in children with acute poststreptococcal glomerulonephritis. ( 15206029 )
2004
24
Endothelin-1 in children with acute poststreptococcal glomerulonephritis and hypertension. ( 12654066 )
2003
25
Thrombocytopenia during the course of acute poststreptococcal glomerulonephritis. ( 12921303 )
2003
26
Acute poststreptococcal glomerulonephritis mimicking Henoch-SchAPnlein purpura. ( 12572934 )
2003
27
Acute poststreptococcal glomerulonephritis and acute rheumatic fever in the same patient: a case report and review of the literature. ( 12967898 )
2003
28
Acute poststreptococcal glomerulonephritis in a child with Bardet-Biedl syndrome. ( 11793138 )
2002
29
Another case of acute poststreptococcal glomerulonephritis with recurrence. ( 12162274 )
2002
30
Acute poststreptococcal glomerulonephritis: public health implications of recent clusters in New South Wales and epidemiology of hospital admissions. ( 11467793 )
2001
31
Recurrence of acute poststreptococcal glomerulonephritis. ( 11465811 )
2001
32
Prognosis of acute poststreptococcal glomerulonephritis (APSGN) is excellent in children, when adequately diagnosed. ( 11472580 )
2001
33
Acute poststreptococcal glomerulonephritis following circumcision. ( 11149125 )
2000
34
The potential role for nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis. ( 10816380 )
2000
35
Acute poststreptococcal glomerulonephritis associated with thrombotic microangiopathy in an adult. ( 10968697 )
2000
36
Renal function during and after childhood acute poststreptococcal glomerulonephritis. ( 10603146 )
1999
37
Frequency of microscopic hematuria in acute poststreptococcal glomerulonephritis. ( 10353421 )
1999
38
Evaluating the use of penicillin to control outbreaks of acute poststreptococcal glomerulonephritis. ( 10223684 )
1999
39
Anticardiolipin antibodies in acute poststreptococcal glomerulonephritis and streptococcal impetigo. ( 10461035 )
1999
40
Acute poststreptococcal glomerulonephritis presenting with hemoptysis. ( 9686966 )
1998
41
C3 mesangial proliferative glomerulonephritis--an evaluation of acute poststreptococcal glomerulonephritis? ( 9518184 )
1997
42
Renal functional reserve after acute poststreptococcal glomerulonephritis. ( 9260248 )
1997
43
Acute poststreptococcal glomerulonephritis in children. ( 9331614 )
1997
44
Searching for acute poststreptococcal glomerulonephritis-associated Streptococcus pyogenes in Australian aboriginal communities. ( 9331610 )
1997
45
Asymptomatic acute poststreptococcal glomerulonephritis following upper respiratory tract infections caused by Group A streptococci. ( 8953117 )
1996
46
An experimental model for acute poststreptococcal glomerulonephritis in mice. ( 8982244 )
1996
47
Myocardial dysfunction in a 23-month child with acute poststreptococcal glomerulonephritis. ( 7793601 )
1995
48
Renal hydatid cyst detected in a child during the course of acute poststreptococcal glomerulonephritis. ( 7723915 )
1995
49
Cell-mediated immune response in acute poststreptococcal glomerulonephritis. ( 8022104 )
1994
50
Cranial computed tomographic findings in a patient with hypertensive encephalopathy in acute poststreptococcal glomerulonephritis. ( 7825239 )
1994

Variations for Acute Poststreptococcal Glomerulonephritis

Expression for Acute Poststreptococcal Glomerulonephritis

Search GEO for disease gene expression data for Acute Poststreptococcal Glomerulonephritis.

Pathways for Acute Poststreptococcal Glomerulonephritis

Pathways related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.27 C4BPA PLG SERPINF2
2 11.05 EDN1 EDNRB
3 10.79 EDN1 EDNRB
4 10.63 EDN1 EDNRB
5 9.74 PLG SERPINF2

GO Terms for Acute Poststreptococcal Glomerulonephritis

Cellular components related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.43 C4BPA CFP EDN1 NPPA PLG SERPINF2
2 blood microparticle GO:0072562 9.33 C4BPA PLG SERPINF2
3 platelet alpha granule lumen GO:0031093 9.26 PLG SERPINF2
4 extracellular space GO:0005615 9.1 C4BPA CFP EDN1 NPPA PLG SERPINF2

Biological processes related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 19)
id Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.73 CD79A EDN1 EDNRB
2 positive regulation of smooth muscle cell proliferation GO:0048661 9.58 EDN1 SERPINF2
3 sensory perception of pain GO:0019233 9.58 EDN1 EDNRB
4 calcium-mediated signaling GO:0019722 9.57 EDN1 EDNRB
5 blood vessel morphogenesis GO:0048514 9.55 EDN1 SERPINF2
6 regulation of sensory perception of pain GO:0051930 9.54 EDN1 EDNRB
7 fibrinolysis GO:0042730 9.52 PLG SERPINF2
8 regulation of pH GO:0006885 9.51 EDN1 EDNRB
9 positive regulation of heart rate GO:0010460 9.49 EDN1 NPPA
10 vasoconstriction GO:0042310 9.48 EDN1 EDNRB
11 regulation of blood vessel size GO:0050880 9.46 EDN1 NPPA
12 response to muscle stretch GO:0035994 9.43 EDN1 NPPA
13 positive regulation of urine volume GO:0035810 9.4 EDN1 EDNRB
14 positive regulation of renal sodium excretion GO:0035815 9.37 EDN1 EDNRB
15 negative regulation of fibrinolysis GO:0051918 9.32 PLG SERPINF2
16 epithelial fluid transport GO:0042045 9.26 EDN1 EDNRB
17 negative regulation of cellular protein metabolic process GO:0032269 9.16 EDN1 EDNRB
18 regulation of blood pressure GO:0008217 9.13 EDN1 EDNRB NPPA
19 vein smooth muscle contraction GO:0014826 8.62 EDN1 EDNRB

Molecular functions related to Acute Poststreptococcal Glomerulonephritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 8.8 EDN1 NPPA PLG

Sources for Acute Poststreptococcal Glomerulonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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