MCID: ACT042
MIFTS: 45

Acute Pyelonephritis malady

Category: Nephrological diseases

Aliases & Classifications for Acute Pyelonephritis

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Aliases & Descriptions for Acute Pyelonephritis:

Name: Acute Pyelonephritis 11 50 13 68
 
Acute Pyelonephritis Nos 11

Classifications:



External Ids:

Disease Ontology11 DOID:559
ICD1030 N10
ICD9CM32 590.1
NCIt45 C123215

Summaries for Acute Pyelonephritis

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MalaCards based summary: Acute Pyelonephritis, also known as acute pyelonephritis nos, is related to pyelonephritis and coloboma of iris. An important gene associated with Acute Pyelonephritis is CRP (C-Reactive Protein), and among its related pathways are Cytokines and Inflammatory Response and Overview of nanoparticle effects. Affiliated tissues include kidney, neutrophil and testes, and related mouse phenotypes are liver/biliary system and neoplasm.

Related Diseases for Acute Pyelonephritis

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Diseases in the Pyelonephritis family:

Chronic Pyelonephritis acute pyelonephritis

Diseases related to Acute Pyelonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 190)
idRelated DiseaseScoreTop Affiliating Genes
1pyelonephritis31.5CRP, CXCL8, IL10
2coloboma of iris10.3CRP, IL6
3cutaneous sclerosis10.3CRP, IL6
4unilateral multicystic dysplastic kidney10.3CRP, IL6
5oculomotor nerve paralysis10.3CXCL8, IL6
6common peroneal nerve lesion10.3CXCL8, IL6
7sosby syndrome10.3CRP, CXCL8
8neutrophilia, hereditary10.3CRP, IL6
9swine influenza10.3CRP, IL6
10cardiac tuberculosis10.3CRP, IL6
11thymic neuroendocrine carcinoma10.3CXCL8, IL6
12psychotic disorder10.2CXCL8, IL6
13retinal vascular disease10.2CXCL8, IL6
14ureter inverted papilloma10.2IL10, IL6
15cicatricial lagophthalmos10.2CRP, CXCL8, IL6
16neuropathy10.2CRP, CXCL8, IL6
17cataract, total congenital10.2CRP, IL6
18schwannoma of ureter10.2CXCL8, CXCR1, IL6
19limb ischemia10.2CRP, CXCL8, IL6
20inner ear disease10.2ALB, IL6
21diabetic encephalopathy10.2CRP, CXCL8, IL6
22neovascular glaucoma10.2CRP, CXCL8, IL6
23laryngotracheoesophageal cleft type 210.2CRP, IL6
24conidiobolomycosis10.2CXCL8, IL10
25synovium cancer10.2CRP, CXCL8, IL6
26inflammatory bowel disease 2010.2CXCL8, IL10
27microglandular adenosis of breast10.2CXCL8, IL10
28cataract10.2ALB, CRP
29coronary arterial fistulas10.2CXCL8, IL10
30shoulder impingement syndrome10.2ALB, CRP, IL6
31histiocytosis10.2CRP, CXCL8, IL6
32hidradenitis suppurativa10.2CXCL8, IL10
33transient tic disorder10.2IL10, IL6
34hyperlipoproteinemia type iv10.1ALB, CRP, IL6
35ischemic optic neuropathy10.1ALB, CRP, IL6
36gait apraxia10.1ALB, CRP, IL6
37rift valley fever10.1ALB, CRP, IL6
38capillary leak syndrome10.1ALB, CRP, CXCL8
39cervix small cell carcinoma10.1ADM, CRP, IL6
40central nervous system leiomyoma10.1ALB, CRP, IL6
41spondyloarthropathy 210.1ALB, NAGLU
42familial nephrotic syndrome10.1ALB, CRP, IL6
43bacterial meningitis10.1ALB, CRP, IL6
44labyrinthine bilateral reactive loss10.1ALB, CXCL8, IL6
45congenital chloride diarrhea10.1ALB, CRP, IL6
46multiple mitochondrial dysfunctions syndrome10.1CRP, IL10, IL6
47chronic myocardial ischemia10.1ALB, CRP, IL6
48follicular adenoma10.1CRP, IL10, IL6
49peroneal neuropathy10.1ALB, CRP, IL6
50paranasal sinus sarcoma10.1ALB, CXCL8, IL6

Graphical network of the top 20 diseases related to Acute Pyelonephritis:



Diseases related to acute pyelonephritis

Symptoms & Phenotypes for Acute Pyelonephritis

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MGI Mouse Phenotypes related to Acute Pyelonephritis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.5ADM, ALB, CXCR2, IL10, IL6, NAGLU
2MP:00020067.9ALB, CXCR2, IL10, IL6, PGF
3MP:00053857.3ADM, CRP, CXCL10, CXCR2, IL10, IL6
4MP:00053877.0ADM, CRP, CXCL10, CXCR1, CXCR2, IL10

Drugs & Therapeutics for Acute Pyelonephritis

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Drugs for Acute Pyelonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 91)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
SulfamethoxazoleapprovedPhase 4, Phase 3161723-46-65329
Synonyms:
129378-89-8
3-(Para-Aminophenylsulphonamido)-5-methylisoxazole
3-(p-Aminobenzenesulfonamido)-5-methylisoxazole
3-(p-Aminophenylsulfonamido)-5-methylisoxazole
3-(para-Aminophenylsulphonamido)-5-methylisoxazole
3-Sulfanilamido-5-methylisoxazole
3-Sulphanilamido-5-methylisoxazole
4-Amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
4-Amino-N-(5-methyl-3-isoxazolyl)-Benzenesulfonamide
4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide
4-Amino-N-(5-methyl-isoxazol-3-yl)-benzenesulfonamide
4-Amino-N-[5-methyl-3- isoxazolyl]benzenesulfonamide
4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
4-amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide
46850_RIEDEL
5-Methyl-3-sulfanilamidoisoxazole
5-Methyl-3-sulfanylamidoisoxazole
5-Methyl-3-sulfonylamidoisoxazole
5-Methyl-3-sulphanil-amidoisoxazole
723-46-6
A047
AB00052099
AC-11118
AC1L1K42
AC1Q2J5R
AKOS000200952
ALBB-002089
ARONIS018156
Apo-Sulfamethoxazole
Azo Gantanol
Azo-Gantanol
Azo-gantanol
BAS 00836086
BB_SC-1251
BIDD:GT0731
BPBio1_000081
BRD-K28494619-001-05-0
BRN 0226453
BSPBio_000073
BSPBio_002028
Bactrim
Bactrimel
C07315
C10H11N3O3S
CAS-723-46-6
CCRIS 567
CHEBI:9332
CHEMBL443
CID5329
CPD000058223
D00447
D013420
DB01015
DivK1c_000649
EINECS 211-963-3
Gamazole
Gantanol
Gantanol (TN)
Gantanol (tn)
Gantanol-DS
HMS1568D15
HMS1921A21
HMS2092K03
HMS502A11
HMS561O18
HSDB 3186
I01-0154
IDI1_000649
InChI=1/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
KBio1_000649
KBio2_001474
KBio2_004042
KBio2_006610
KBio3_001528
KBioGR_000749
KBioSS_001474
LS-1620
MLS000069732
MLS001055354
MLS001074165
MS 53
Maybridge1_007190
Metoxal
MolPort-000-145-787
N'-(5-Methyl-3-isoxazole)sulfanilamide
 
N'-(5-Methyl-3-isoxazolyl)-Sulfanilamide
N'-(5-Methyl-3-isoxazolyl)sulfanilamide
N'-(5-Methylisoxazol-3-yl)sulphanilamide
N(Sup1)-(5-Methyl-3-isoxazolyl)sulfanilamide
N(sup 1)-(5-Methyl-3-isoxazolyl)sulfanilamide
N(sup 1)-(5-Methyl-3-isoxazolyl)sulphanilamide
N(sup1)-(5-Methyl-3-isoxazolyl)sulfanilamide
N1-(5-Methyl-3-isoxazolyl)sulfanilamide
N1-(5-Methyl-3-isoxazolyl)sulphanilamide
N1-(5-Methylisoxazol-3-yl)sulfanilamide
N1-(5-methyl-3-isoxazolyl)-Sulfanilamide
NCGC00016533-01
NCGC00016533-02
NCGC00021995-03
NCGC00021995-04
NCGC00021995-05
NINDS_000649
NSC 147832
NSC147832
N^1-(5-Methyl-3-isoxazolyl)-Sulfanilamide
Ndimethyl1-(5-methyl-3-isoxazolyl)-Sulfanilamide
Oprea1_114486
Oprea1_285680
Prestwick0_000177
Prestwick1_000177
Prestwick2_000177
Prestwick3_000177
Prestwick_453
Radonil
Ro 4-2130
Ro 6-2580/11
Ro-4-2130
S0361
S1915_Selleck
S7507_FLUKA
S7507_SIGMA
SAM002554930
SIM
SMR000058223
SMX
SPBio_000896
SPBio_001994
SPECTRUM1500550
STK007988
SULFAMETHOXAZOLE (8064-90-2 (TRIMETHOPRIM/SULFAMETHOXAZOLE)
Septran
Simsinomin
Sinomin
Solfametossazolo
Solfametossazolo [DCIT]
Spectrum2_000788
Spectrum3_000584
Spectrum4_000345
Spectrum5_000982
Spectrum_000994
Sulfamethalazole
Sulfamethoxazol
Sulfamethoxazole
Sulfamethoxazole (JP15/USP/INN)
Sulfamethoxazole [USAN:INN:JAN]
Sulfamethoxazole sodium
Sulfamethoxazole(USAN)
Sulfamethoxazolum
Sulfamethoxazolum [INN-Latin]
Sulfamethoxizole
Sulfamethylisoxazole
Sulfametoxazol
Sulfametoxazol [INN-Spanish]
Sulfanilamide, N1-(5-methyl-3-isoxazolyl)- (8CI)
Sulfisomezole
Sulpha-Methoxizole
Sulpha-methoxizole
Sulphamethalazole
Sulphamethoxazol
Sulphamethoxazole
Sulphamethoxazole BP 98
Sulphamethylisoxazole
Sulphisomezole
TL8005058
TMP/SMX (MIXTURE))
Trib
UNII-JE42381TNV
Urobak
WLN: T5NOJ C1 EMSWR DZ
ZINC00089763
nchembio.221-comp24
sulfamethoxazole
2
Levofloxacinapproved, investigationalPhase 4, Phase 3, Phase 2236100986-85-4149096
Synonyms:
(−
(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyridol[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7Hpyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate
(-)-Ofloxacin
(3S)-(-)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(R)-isomer
(S)-(-)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid
(S)-(-)-Ofloxacin
(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(S)-Ofloxacin
)-Ofloxacin
100986-85-4
100986-86-5
28266_FLUKA
28266_SIGMA
AC-7593
AC1L3YF8
Aeroquin
Ambap100986-85-4
BRD-K09471561-001-06-7
BSPBio_002689
C07660
C18H20FN3O4
C18H20FN3O4.H2O
CCRIS 4073
CCRIS 4074
CHEMBL33
CID149096
CPD000466387
Cravit
Cravit (TN)
Cravit Ophthalmic
D08120
DB01137
DR 3354
DR-3355
DR-3355: L-isomer of ofloxacin
DR3355
Elequine
Floxacin
Floxel
Floxin
HMS1922J07
HMS2051G04
HMS2090O10
HMS2093E18
HR 355
HR-355
Iquix
KBio2_002199
KBio2_004767
KBio2_007335
KBio3_001909
 
KBioGR_001605
KBioSS_002199
L-Ofloxacin
L-ofloxacin
L0193
LEVAQUIN IN DEXTROSE 5% IN PLASTIC CONTAINER
LEVOFLOXACIN
LFX
LS-133260
LS-171761
LVX
Leroxacin
Lesacin
Levaquin
Levofloxacin
Levofloxacin (INN)
Levofloxacin [USAN:INN:JAN]
Levofloxacin hydrate
Levofloxacin tablet, suspension or intravenous
Levofloxacine
Levofloxacine [INN-French]
Levofloxacino
Levofloxacino [INN-Spanish]
Levofloxacinum
Levofloxacinum [INN-Latin]
Levokacin
Levox
Levoxacin
MLS000759524
MLS001165709
MLS001423977
MP-376
MolPort-002-885-835
Mosardal
NCGC00178529-01
Nofaxin
Ofloxacin
Ofloxacin S-(-)-form
Oftaquix
Quixin
R-Ofloxacin
RWJ 25213-097
RWJ-25213
Reskuin
S-(-)-Ofloxacin
S1940_Selleck
SAM001246758
SMR000466387
SPBio_001891
SPECTRUM1504260
Spectrum2_001676
Spectrum3_000995
Spectrum4_001123
Spectrum5_001438
Spectrum_001719
Tavanic
Volequin
d-Levofloxacin
3
Nitrofurantoinapproved, vet_approvedPhase 43667-20-95353830
Synonyms:
1-(((5-nitro-2-furanyl)methylene)amino)-2,4-imidazolidinedione
1-((5-Nitrofurfurylidene)amino)hydantoin
1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedione
1-((5-nitrofurfurylidene)amino)hydantoin
1-(5-Nitro-2-furfurylidenamino)hydantoin
1-(5-Nitro-2-furfurylideneamino)hydantoin
1-[(5-:nitrofurfurylidene)amino]hydantoin
1-[(5-Nitrofurfurylidene)amino]hydantoin
1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
1-[[(5-Nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione
1-{[(1E)-(5-nitro-2-furyl)methylene]amino}imidazolidine-2,4-dione
1-{[(1E)-(5-nitrofuran-2-yl)methylidene]amino}imidazolidine-2,4-dione
17140-81-7 (mono-hydrate)
5-Nitrofurantoin
54-87-5 (hydrochloride salt)
67-20-9
AB00513815
AC1O7GAU
AI3-26388
AKOS001678301
Alfuran
Apo-Nitrofurantoin
BIDD:GT0181
BPBio1_000039
BRD-K76927775-001-05-0
BSPBio_000035
BSPBio_002073
Benkfuran
Berkfuran
Berkfurin
Bio-0352
C8H6N4O5
CCRIS 1192
CHEMBL572
CID6604200
Ceduran
Chemiofuran
Cistofuran
Cyantin
Cystit
D00439
Dantafur
EINECS 200-646-5
Fua Med
Fuamed
Fur-Ren
Fur-ren
Furabid
Furachel
Furadantin
Furadantin (TN)
Furadantin Retard
Furadantina MC
Furadantine
Furadantine Mc
Furadantine mc
Furadantine-MC
Furadantine-Mc
Furadantoin
Furadoin
Furadoine
Furadonin
Furadonine
Furadoninum
Furadontin
Furalan
Furaloid
Furan
Furanite
Furantoin
Furantoina
Furatoin
Furedan
Furina
Furobactina
Furodantin
Furophen T
Furophen T-Caps
Gerofuran
HMS1568B17
HMS1920P21
HMS2091H16
HMS500L06
HSDB 3135
I07-0015
IDI1_000224
It-Uran
Ituran
Ivadantin
 
LS-1560
Macpac
Macrobid
Macrodantin
Macrodantina
Macrofuran
Macrofurin
MolPort-001-018-217
N-(5-Nitro-2-furfurylidene)-1-aminohydantoin
N-(5-Nitro-2-furfurylideno)-1-aminohydantoina
N-(5-Nitro-2-furfurylideno)-1-aminohydantoina [Polish]
N-(5-Nitrofurfurylidene)-1-aminohydantoin
N-(5-nitro-2-furfurylidene)-1-aminohyda ntoin
N-Toin
NCGC00091505-01
NCGC00091505-03
NCGC00091505-04
NCGC00091505-05
NCI-C55196
ND-3320
ND-7248
NITROFURANTION
NITROFURANTOIN MACROCRYSTALLINE
NITROFURANTOIN, MACROCRYSTALLINE
NSC 2107
NSC 44150
NSC2107
NSC44150
Nierofu
Nifurantin
Nifuretten
Nitoin
Nitrex
Nitrofan
Nitrofur-C
Nitrofuradantin
Nitrofurantoin (JAN/USP/INN)
Nitrofurantoin [USAN:INN:BAN:JAN]
Nitrofurantoin anhydrous
Nitrofurantoin macrocrystal
Nitrofurantoin macrocrystalline
Nitrofurantoin, macrocrystalline
Nitrofurantoin, macrocrystals
Nitrofurantoina
Nitrofurantoina [DCIT]
Nitrofurantoine
Nitrofurantoine [INN-French]
Nitrofurantoinum
Nitrofurantoinum [INN-Latin]
Nitrofurantoinum anhydrous
Novo-Furantoin
Novofuran
Orafuran
Parfuran
Phenurin
PiyEloseptyl
Prestwick2_000168
Prestwick3_000168
Prestwick_358
Ro-Antoin
SPECTRUM1500433
Siraliden
Spectrum5_001367
Trantoin
UNII-927AH8112L
USAF EA-2
Uerineks
Upiol
Urantoin
Urizept
Uro-Selz
Uro-Tablinen
Urodin
Urofuran
Urofurin
Urolisa
Urolong
Usaf ea-2
Uvaleral
Welfurin
ZINC07997568
Zoofurin
fua-med
furophen
nitrofurantoin
nitrofurantoina
nitrofurantoine
nitrofurantoinum
uro-tablineu
urodil
4
OfloxacinapprovedPhase 4, Phase 3, Phase 223682419-36-14583
Synonyms:
( -)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazin-6-carbonsaeure
(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperaz inyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- -oxo-7H-pyrido(1,2,3-de)- -1,4-benzoxazine-6-carboxylic acid
(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
(+/-)-Floxin
118120-51-7 (hydrochloride)
33703_FLUKA
33703_RIEDEL
8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
82419-36-1
83380-47-6
85344-55-4
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
AB00513820
AC-7616
AC1L1IHM
AKOS001033517
BB_SC-1252
BPBio1_000345
BRD-A24228527-001-05-9
BRN 3657947
BSPBio_000313
BSPBio_003117
Bactocin
C07321
C18H20FN3O4
CCRIS 5233
CHEBI:7731
CHEMBL4
CID4583
CPD000058192
D00453
DB01165
DEXTROFLOXACINE
DL 8280
DL-8280
DL-8280, HOE-280, Exocin, Flobacin, Floxin, Floxil, Monoflocet, Ofloxacin
Danoflox
DivK1c_000721
EU-0100904
Effexin
Exocin
Exocine
FLOXIN IN DEXTROSE 5%
FLOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER
Flobacin
Flodemex
Flotavid
Flovid
Floxal
Floxil
Floxin
Floxin (TN)
Floxin otic
Floxstat
Fugacin
HMS1568P15
HMS1921H12
HMS2090F07
HMS2092B10
HMS502E03
HOE 280
Hoe-280
I06-0112
I06-0380
IDI1_000721
Inoflox
KBio1_000721
KBio2_001666
KBio2_004234
KBio2_006802
KBio3_002617
KBioGR_000667
KBioSS_001666
Kinflocin
Kinoxacin
LS-133259
Liflox
Lopac0_000904
Loxinter
MLS000028749
MLS001074203
Marfloxacin
Medofloxine
Mergexin
MolPort-000-422-241
MolPort-000-873-068
NCGC00015772-02
NCGC00015772-10
 
NCGC00094219-01
NCGC00094219-02
NCGC00094219-03
NCGC00094219-04
NCGC00094219-05
NCGC00094219-06
NCGC00178284-01
NCGC00178284-02
NINDS_000721
NSC727071
Novecin
Nufafloqo
O 8757
O-Flox
O8757_SIGMA
OFLX
OFX
ORF 18489
ORF-28489
Obide
Occidal
Ocuflox
Ofcin
Oflin
Oflocee
Oflocet
Oflocin
Oflodal
Oflodex
Oflodura
Oflox
Ofloxacin (JP15/USP/INN)
Ofloxacin Otic
Ofloxacin [USAN:BAN:INN:JAN]
Ofloxacin, (S)-Isomer
Ofloxacina
Ofloxacina [DCIT]
Ofloxacine
Ofloxacine [French]
Ofloxacino
Ofloxacino [Spanish]
Ofloxacinum
Ofloxacinum [Latin]
Ofloxin
Ofus
Onexacin
Operan
Oprea1_242882
Orocin
Otonil
Oxaldin
PT 01
Pharflox
Praxin
Prestwick0_000237
Prestwick1_000237
Prestwick2_000237
Prestwick3_000237
Puiritol
Qinolon
Qipro
Quinolon
Quotavil
Rilox
Ru-43280
S1463_Selleck
SAM002264629
SMR000058192
SPBio_001387
SPBio_002234
SPECTRUM1502044
STK256723
Sinflo
Spectrum2_001464
Spectrum3_001499
Spectrum4_000324
Spectrum5_001063
Spectrum_001186
Tabrin
Taravid
Tariflox
Tarivid
Telbit
Tructum
UNII-A4P49JAZ9H
Uro Tarivid
Viotisone
Visiren
WP-0405
XED
Zanocin
ofloxacin
5
Ciprofloxacinapproved, investigationalPhase 4, Phase 3, Phase 223685721-33-12764
Synonyms:
1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperzinyl)-3-quinolinecarboxylic acid HCl H2O
1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinoline carboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
17850_FLUKA
3-Quinolinecarboxylic acid,1,4-dihydro-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)
33434_FLUKA
33434_RIEDEL
85721-33-1
AC-7613
AC1L1EEW
AKOS000269653
ARONIS020379
Alcon Cilox
BAS 06989041
BAY q 3939
BAY-Q-3939
BAYQ3939
BIDD:GT0205
BPBio1_000140
BRD-K04804440-311-02-3
BRN 3568352
BSPBio_000126
BSPBio_003344
Bacquinor
Baflox
Bay o 9867
Bay o 9867 (*Hydrochloride*)
Bay-09867
Baycip
Bernoflox
Bi-Cipro
Bio-0540
C05349
C17H18FN3O3
CAS-93107-08-5
CBMicro_048498
CCRIS 5241
CHEBI:100241
CHEMBL8
CID2764
CIPRO IN DEXTROSE 5% IN PLASTIC CONTAINER
CIPRO IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
CPF
CPFX
CRL-1605 & Ciprofloxacin
Ciflox
Cifloxin
Cilab
Ciloxan
Ciloxan (*Hydrochloride*)
Ciplus
Ciprecu
Ciprinol
Cipro
Cipro (*Hydrochloride*)
Cipro (TN)
Cipro I.V.
Cipro IV
Cipro XL
Cipro XR
Ciprobay
Ciprobay Uro
Ciprocinol
Ciprodar
Ciproflox
Ciprofloxacin (JAN/USP/INN)
Ciprofloxacin HCl
Ciprofloxacin Hydrchloride
Ciprofloxacin [USAN:INN:BAN]
Ciprofloxacin dihydrochloride
Ciprofloxacin hydrochloride
Ciprofloxacin monohydrochloride
Ciprofloxacina
Ciprofloxacine
Ciprofloxacine [INN-French]
Ciprofloxacino
Ciprofloxacino [INN-Spanish]
Ciprofloxacinum
 
Ciprofloxacinum [INN-Latin]
Ciprogis
Ciprolin
Ciprolon
Cipromycin
Ciproquinol
Ciprowin
Ciproxan
Ciproxin
Ciproxina
Ciproxine
Ciriax
Citopcin
Cixan
Corsacin
Cycin
Cyprobay
D00186
DB00537
DivK1c_000095
Eni
Fimoflox
Flociprin
Floxin
HMS1922E18
HMS2090O07
HMS2093I03
HMS500E17
HSDB 6987
IDI1_000095
Ipiflox
Italnik
KBio1_000095
KBio2_000642
KBio2_003210
KBio2_005778
KBio3_002846
KBioGR_001567
KBioSS_000642
LS-141563
Liposomal-ciprofloxacin
Loxan
MLS001336035
MolPort-000-819-654
NCGC00016959-01
NCGC00095058-01
NCGC00095058-02
NCGC00178128-01
NINDS_000095
NSC620634
Ocuflox
Oprea1_008239
Oprea1_313572
Prestwick0_000113
Prestwick1_000113
Prestwick2_000113
Prestwick3_000113
Probiox
Proflaxin
Proflox
Proksi 250
Proksi 500
Proquin XR
Quinolid
Quintor
Rancif
Roxytal
SMP1_000125
SMR000471901
SPBio_001474
SPBio_002065
SPECTRUM1503614
STK021082
Septicide
Sophixin Ofteno
Spectrum2_001567
Spectrum3_001872
Spectrum4_000874
Spectrum5_001089
Spectrum_000162
Spitacin
Superocin
UNII-5E8K9I0O4U
Unex
Velomonit
Zumaflox
ciprofloxacin
nchembio820-comp1
6
Trimethoprimapproved, vet_approvedPhase 4, Phase 3177738-70-55578
Synonyms:
2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
46984_FLUKA
46984_RIEDEL
5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine
738-70-5
92131_FLUKA
92131_SIGMA
AB00052118
AB1004879
AC-13572
AC1L1KNQ
AC1Q48DF
AI3-52594
AKOS001650069
ARONIS24118
AZT + TMP/SMX (mixture) combination
Abacin
Abaprim
Alcorim-F
Alprim
Anitrim
Antrima
Antrimox
Apo-Sulfatrim
BB_SC-2116
BIDD:GT0190
BPBio1_000215
BRD-K07208025-001-06-5
BRN 0625127
BSPBio_000195
BSPBio_002245
BW 56-72
BW 5672
BW-56-72
Bacdan
Bacidal
Bacide
Bacin
Bacta
Bacterial
Bacterial [Antibiotic]
Bacticel
Bactin
Bactoprim
Bactramin
Bactrim
Bactrim DS
Bactrim Pediatric
Baktar
Bencole
Bethaprim
Biosulten
Briscotrim
C01965
CAS-738-70-5
CCRIS 2410
CHEBI:45924
CHEMBL22
CID5578
CPD0-1581
CPD000035999
Chemotrim
Chemotrin
Cidal
Co-Trimoxizole
Co-trimoxazole
Colizole
Colizole DS
Comox
Conprim
Cotrim
Cotrim D.S.
Cotrimel
D00145
D014295
DB00440
Deprim
DivK1c_000589
Drylin
Duocide
EINECS 212-006-2
EU-0101271
Esbesul
Espectrin
Euctrim
Eusaprim
Exbesul
Fectrim
Fermagex
Fortrim
Futin
Gantaprim
Gantrim
HMS1568J17
HMS1921I03
HMS2090D14
HMS2092A10
HMS501N11
HSDB 6781
I06-0086
IDI1_000589
Idotrim
Ikaprim
Imexim
Instalac
Ipral
KBio1_000589
KBio2_000647
KBio2_003215
KBio2_005783
KBio3_001465
KBioGR_000863
KBioSS_000647
KSC-4-158
KUC103659N
Kepinol
Kombinax
LS-1627
Lagatrim
Lagatrim Forte
Laratrim
Lastrim
Lidaprim
Linaris
Lopac-T-7883
Lopac0_001271
MLS000079023
MLS001201740
MLS002303068
Methoprim
Metoprim
Microtrim
MolPort-001-826-685
Monoprim
Monotrim
Monotrimin
NCGC00016055-01
NCGC00016055-02
NCGC00016055-06
NCGC00016055-12
NCGC00024707-01
NCGC00024707-03
NCGC00024707-04
NCGC00024707-05
NCGC00024707-06
NCGC00024707-07
NCGC00024707-08
NIH 204
 
NIH 204 (VAN)
NINDS_000589
NSC 106568
NSC-106568
NSC106568
Nopil
Novotrimel
Omstat
Oprea1_495058
Oraprim
Pancidim
Polytrim
Prestwick0_000208
Prestwick1_000208
Prestwick2_000208
Prestwick3_000208
Prestwick_485
Priloprim
Primosept
Primsol
Proloprim
Proloprim (TN)
Protrin
Purbal
Resprim
Resprim Forte
Roubac
Roubal
SAM002264649
SMP2_000262
SMR000035999
SPBio_000874
SPBio_002116
SPECTRUM1500595
STK177322
Salvatrim
Septra
Septra DS
Septra Grape
Septrin
Septrin DS
Septrin Forte
Septrin S
Setprin
Sigaprim
Sinotrim
Smz-Tmp
Spectrum2_000937
Spectrum3_000643
Spectrum4_000372
Spectrum5_001559
Spectrum_000167
Stopan
Streptoplus
Sugaprim
Sulfamar
Sulfamethoprim
Sulfamethoprim-DS
Sulfamethoxazole & Trimethoprim
Sulfatrim
Sulfatrim Pediatric
Sulfatrim-DS
Sulfatrim-SS
Sulfotrim
Sulfoxaprim
Sulmeprim
Sulmeprim Pediatric
Sulprim
Sulthrim
Sultrex
Sumetrolim
Supracombin
Suprim
Syraprim
T 7883
T2286
T7883_SIGMA
TCMDC-125538
TL8005108
TMP/SMX (MIXTURE))
Teleprim
Thiocuran
Tiempe
Tmp-Ratiopharm
Tocris-0650
Toprim
Trigonyl
Trimanyl
Trimesulf
Trimeth/Sulfa
Trimethioprim
Trimethopim(TMP)
Trimethoprim
Trimethoprim & VRC3375
Trimethoprim (JAN/USP/INN)
Trimethoprim [USAN:BAN:INN:JAN]
Trimethoprime
Trimethoprime [INN-French]
Trimethoprimum
Trimethoprimum [INN-Latin]
Trimethopriom
Trimetoprim
Trimetoprim [DCIT]
Trimetoprim [Polish]
Trimetoprima
Trimetoprima [INN-Spanish]
Trimexazole
Trimexol
Trimez-IFSA
Trimezol
Trimogal
Trimono
Trimopan
Trimpex
Trimpex (TN)
Trimpex 200
Triméthoprime
Triprim
Trisul
Trisulcom
Trisulfam
Trisural
U-Prin
UNII-AN164J8Y0X
UPCMLD-DP132
UPCMLD-DP132:001
Unitrim
Uretrim
Uro-D S
Uro-Septra
Urobactrim
Uroplus
Uroplus DS
Uroplus SS
Utetrin
Velaten
WLN: T6N CNJ BZ DZ E1R CO1 DO1 EO1
WR 5949
Wellcoprim
Wellcoprin
Xeroprim
ZINC06627681
Zamboprim
component of Bactrim
component of Septra
nchembio.108-comp1
nchembio.215-comp11
nchembio.221-comp23
trimethoprim
7
CefiximeapprovedPhase 42279350-37-154362, 5362065
Synonyms:
(-)-Cefixim
(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethyloxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(carboxymethyl)oxy]imino}acetyl]amino}-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6r,7r)-7-[-2-(2-amino-thiazol-4-yl)-2-carboxymethoxyimino-acetylamino]-8-oxo-3-vinyl-5-thia-1-aza-b
79350-37-1
7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido}-3-ethenyl-3,4-didehydrocepham-4-carboxylic acid
AB00513842
AC-4350
AC1NSFNI
BPBio1_000622
BRD-K71059170-001-02-5
BSPBio_000564
C06881
CEFIXIME
CFIX
CHEBI:472657
CHEBI:530642
CHEMBL1541
CID5362065
 
CL-284635
Cefixim
Cefixima
Cefixima [Spanish]
Cefixime (JP15/USP/INN)
Cefixime Anhydrous
Cefiximum
Cefiximum [Latin]
Céfixime
D00258
Denvar
FK-027
FR-17027
LS-187248
MLS002222332
MolPort-003-845-687
NCGC00179521-01
Necopen
Prestwick3_000462
SMR001307271
Suprax (TN)
Tricef
8
CeftriaxoneapprovedPhase 411973384-59-55479530, 5361919
Synonyms:
(6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-yl)thio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7(sup 2)-(Z)-(O-methyloxime), sesquaterhydrate
(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(methyloxy)imino]acetyl}amino)-3-{[(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
104376-79-6
104376-79-6 (di-hydrochloride salt)
73384-59-5
74578-69-1 (di-hydrochloride salt, hemiheptahydrate)
7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid
AC-1592
AC1NUIFE
Biotrakson
C06683
C18H18N8O7S3
CEFTRIAXONE SODIUM
CHEBI:29007
CHEMBL161
CID5479530
CTRX
Cefatriaxone
Ceftriaxon
Ceftriaxona
Ceftriaxona [INN-Spanish]
 
Ceftriaxone (INN)
Ceftriaxone (TN)
Ceftriaxone [USAN:JAN]
Ceftriaxone intravenous
Ceftriaxone, Disodium Salt
Ceftriaxone, Disodium Salt, Hemiheptahydrate
Ceftriaxonum
Ceftriaxonum [INN-Latin]
Ceftriazone
D07659
DB01212
DRG-0071
EINECS 277-405-6
LS-150031
Longacef
Longaceph
MolPort-005-933-495
Ro 139904
Ro-13-9904
Ro13-9904
Rocefin
Rocephin
Rocephine
UNII-75J73V1629
ceftriaxone
9
leucovorinapproved, NutraceuticalPhase 4, Phase 3323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
10
Folic Acidapproved, nutraceutical, vet_approvedPhase 4, Phase 3439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
11Anti-Bacterial AgentsPhase 4, Phase 3, Phase 211226
12Antibiotics, AntitubercularPhase 4, Phase 3, Phase 27180
13Anti-Infective AgentsPhase 4, Phase 3, Phase 222062
14Trimethoprim, Sulfamethoxazole Drug CombinationPhase 4, Phase 3168
15Antiprotozoal AgentsPhase 4, Phase 32051
16Folic Acid AntagonistsPhase 4, Phase 32257
17Vitamin B ComplexPhase 4, Phase 34337
18Renal AgentsPhase 4, Phase 3, Phase 2754
19Cytochrome P-450 Enzyme InhibitorsPhase 4, Phase 3, Phase 23917
20Cytochrome P-450 CYP1A2 InhibitorsPhase 4, Phase 3, Phase 2572
21Antitubercular AgentsPhase 4, Phase 31343
22FluoroquinolonesPhase 4, Phase 2392
23Nucleic Acid Synthesis InhibitorsPhase 4, Phase 24962
24AntimalarialsPhase 4, Phase 31246
25Topoisomerase InhibitorsPhase 4, Phase 3, Phase 25069
26LactamsPhase 4113
27Antiparasitic AgentsPhase 4, Phase 32199
28FolateNutraceuticalPhase 4, Phase 34392
29Vitamin B9NutraceuticalPhase 4, Phase 34392
30
TazobactamapprovedPhase 3, Phase 210389786-04-9123630
Synonyms:
(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4
(2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
89785-84-2
89786-04-9
AC-7620
AC1L3X07
BIDD:GT0212
C07771
CHEBI:100207
CHEMBL404
 
CID123630
CL-298741
CL298741
D00660
DB01606
MolPort-002-500-123
TAZ
Tazobactam
Tazobactam (JAN/USAN/INN)
YTR-830H
YTR830H
31
CeftazidimeapprovedPhase 36578439-06-25481173
Synonyms:
(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
7-[[2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
72558-82-8
7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate
AB00513848
AC1L1E5K
AC1L3MNA
AC1NUK7U
AC1NUN9Q
BIDD:GT0734
BRN 4344904
C06889
C2225
C22H22N6O7S2
CAZ
CEFTAZIDIME (ARGININE FORMULATION)
CHEBI:3508
CHEMBL201
CID2650
CID5481173
CID5484131
 
Ceftazidim
Ceftazidima
Ceftazidima [INN-Spanish]
Ceftazidime
Ceftazidime (INN)
Ceftazidime (TN)
Ceftazidime Sodium In Plastic Container
Ceftazidime anhydrous
Ceftazidime pentahydrate
Ceftazidimum
Ceftazidimum [INN-Latin]
Ceptaz
Ceptaz (TN)
D07654
DB00438
EINECS 276-715-9
Fortaz
Fortaz (TN)
Fortaz In Plastic Container
HMS2090M13
I06-1102
LS-132194
SN 401
UNII-9M416Z9QNR
ceftazidima
ceftazidime
ceftazidimum
32
Meropenemapproved, investigationalPhase 397119478-56-764778, 441130
Synonyms:
(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate
(1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid
(2S,3R,4R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid
(4R,5S,6S)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5S,6S)-3-((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-ylthio)-6-((S)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid
96036-03-2
AB00514051
AB1004614
AC1L9ALL
Ambap119478-56-7
Antibiotic SM 7338
Antibiotic sm 7338
BIDD:GT0851
BPBio1_001334
BSPBio_001212
CHEBI:43968
CHEMBL127
CID441130
CPD000469184
D08185
HMS1571M14
HMS2051G08
HMS2090C05
 
ICI-194660
MEPM
MERONEM
MLS001401437
Meronem (TN)
Meropen
Meropenem
Meropenem (INN)
Meropenem Hydrate
Meropenem anhydrous
Meropenem trihydrate
Meropenemum
Meropenemum [INN-Latin]
Meropenemum trihydricum
Merrem
Merrem I.V. (TN)
MolPort-006-709-417
NCGC00179259-01
Prestwick0_001106
Prestwick1_001106
Prestwick2_001106
Prestwick3_001106
SAM001246650
SM-7338
SMR000469184
SPBio_003086
33
ColistinapprovedPhase 3641264-72-8, 1066-17-75311054
Synonyms:
1066-17-7
AC1NSJWT
CID5311054
Colistin
Colistin sulfate, nonsterile
Colistin sulphate
 
Colistina
Colistine
Colistinum
DB00803
N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-5-methylheptanamide
Polymyxin E
Polymyxin E. Sulfate
colistin
34AvibactamapprovedPhase 3, Phase 2261192500-31-4
35
PiperacillinapprovedPhase 3, Phase 210166258-76-243672
Synonyms:
(2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S-(2alpha,5alpha,6beta(S*)))-6-(((((4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl)amino)phenylacetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
4-ethyl-2,3-dioxopiperazine carbonyl ampicillin
59703-84-3
59703-84-3 (mono-hydrochloride salt)
6-(D-(-)-alpha-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)phenylacetamido)penicillanic acid
61477-96-1
6beta-{(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylic acid
AC1L2ACR
AC1Q5QXJ
BIDD:GT0167
BPBio1_000848
BRD-K86873305-236-03-0
BSPBio_000770
C14034
C23H27N5O7S
CCRIS 7362
CHEBI:8232
CHEMBL702
CID43672
Cl-227193
D08380
EINECS 262-811-8
HMS2090H19
LS-149794
 
PIPC
PIPERACILLIN SODIUM
Peperacillin
Peracin
Peracin (TN)
Piperacilina
Piperacillin
Piperacillin (INN)
Piperacillin (anhydrous)
Piperacillin Anhydrous
Piperacillin Monosodium Salt
Piperacillin anhydrous
Piperacillina
Piperacillinum
Pipercillin
Pipracil
Pipracil, Piper
Pipril
Pipéracilline
Prestwick0_000755
Prestwick1_000755
Prestwick2_000755
Prestwick3_000755
SPBio_002709
T-1220
UNII-9I628532GX
piperacillin
36
TigecyclineapprovedPhase 357220620-09-75282044
Synonyms:
(4S,12aS)-4,7-Bis(dimethylamino)-9-{2-[(tert-butyl)amino]acetylamino}-3,10,12,12a-tetrahydroxy-1,11-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide
(4S,4AS,5ar,12as)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
(4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
(4S,4aS,5aR,12aS)-9-[(N-tert-butylglycyl)amino]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
121GE002
220620-09-7
9-t-Butylglycylamido minocycline
AC-1798
AC1NQZEU
C12012
CHEBI:149836
CHEMBL1212946
CHEMBL376140
CID5282044
D01079
DB00560
GAR 936
GAR-936
 
GAR-936,Tigecycline
LS-186580
LS-187002
LS-187782
N-[(5aR,6aS,7S,9Z,10aS)-9-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-1,10a,12-trihydroxy-8,10,11-trioxo-5a,6,6a,7-tetrahydro-5H-tetracen-2-yl]-2-(tert-butylamino)acetamide
S1403_Selleck
TBG-MINO
Tigeciclina
Tigecycline
Tigecycline (JAN/USAN)
Tigecycline [USAN]
Tigecyclinum
Tigilcycline
Tygacil
Tygacil (TN)
Tygacil(TM)
Tygacil, GAR-936, WAY-GAR-936, TBG-MINO, Tigecycline
UNII-70JE2N95KR
WAY-GAR-936
37
Minocyclineapproved, investigationalPhase 323110118-90-85281021
Synonyms:
(2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE
(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
10118-90-8
13614-98-7 (mono-hydrochloride)
4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
4708-96-7
7-Dimethylamino-6-demethyl-6-deoxytetracycline
AC1NQXWM
Alti-Minocycline
Apo-Minocycline
Arestin
BRN 3077644
Bio-0062
Borymycin
C07225
C23H27N3O7
CHEBI:50694
CHEBI:529981
CHEMBL1434
CHEMBL259172
CID5281021
CL 59806
CRL-1605 & Minocycline
D05045
Dynacin
Gen-Minocycline
HMS2090D03
HSDB 3130
Klinomycin
 
LMPK07000002
LS-93850
Lactoferrin B & Minocycline
Lactoferrin H & Minocycline
MINO
MIY
Minociclina
Minociclina [INN-Spanish]
Minociclinum
Minocin
Minocin (Hydrochloride)
Minocline
Minocyclin
Minocycline (USAN/INN)
Minocycline HCl
Minocycline Monohydrochloride
Minocycline [USAN:BAN:INN]
Minocyclinum
Minocyclinum [INN-Latin]
Minocyn
Minomycin
NCGC00178854-01
NSC 141993
NSC141993
Novo-Minocycline
Solodyn
UNII-FYY3R43WGO
Vectrin
Vectrin (Hydrochloride)
minociclinum
minocycline
nchembio.559-comp1
38
FosfomycinapprovedPhase 2, Phase 33423155-02-4446987
Synonyms:
(−
(-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid
(1R,2S)(-)-(1,2-Epoxypropyl)phosphonic acid disodium salt
(1R,2S)-Epoxypropylphosphonic acid
(1R,2S)-epoxypropylphosphonate
(1R,2S)-epoxypropylphosphonic acid
(2R-cis)-(3-Methyloxiranyl)phosphonic acid
(2R-cis)-(3-Methyloxiranyl)phosphonic acid disodium salt
)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid
1R-cis-(1,2-Epoxypropyl)phosphonic acid
23155-02-4
26016-99-9
34089_FLUKA
34089_RIEDEL
6F066DFF-696A-4A94-AF78-A28430EBE5BA
AC1L2JXY
AC1L9KC0
AC1Q1URS
AR-1I6648
BIDD:GT0448
BRN 1680831, Fosfocina
C06454
CHEBI:681859
CHEMBL1757
CID446987
CID73491
CPD0-1113
D02188
D04253
DB00828
Disodium (1R,2S)-(1,2-epoxypropyl)phosphonate
Disodium fosfomycin
Disodium phosphonomycin
EINECS 247-409-2
FCM
FOM-Na
FOSFOMYCIN
 
Fosfocina
Fosfocina disodium salt
Fosfomicina
Fosfomycin (USAN/INN)
Fosfomycin disodium
Fosfomycin disodium salt
Fosfomycin sodium
Fosfomycin sodium (JP15)
Fosfomycin sodium salt
Fosfomycine
Fosfomycinum
Fosfonomycin
Fosmicin S
Fosmicin S (TN)
I06-1211
L-cis-1,2-Epoxypropylphosphonic acid
L-cis-1,2-epoxypropylphosphonic acid
LS-106593
MK 955
MolPort-003-847-502
NSC 136017
P5396_SIGMA
Phosphomycin
Phosphomycin disodium salt
Phosphonemycin
Phosphonic acid, (3-methyloxiranyl)-, disodium salt, (2R-cis)- (9CI)
Phosphonomycin
Phosphonomycin disodium salt
Phosphonomycin sodium
Priomicina
Sodium fosfomycin
Veramina
ZINC19594585
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid
cis-(1R,2S)-Epoxypropylphosphonic acid
disodium[(2r,3s)-3-methyloxiran-2-yl]phosphonate
nchem.1024-comp6
phosphomycin
39
CeftibutenapprovedPhase 3797519-39-65282241, 5282242
Synonyms:
(+)-(6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
(+)-(6R,7R)-7-((Z)-2-(2-amino-4-Thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[(E)-2-(2-amino-1,3-thiazol-4-yl)-5-hydroxy-5-oxopent-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-5-hydroxy-5-oxopent-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-5-hydroxy-5-oxopent-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-[[(E)-2-(2-amino-1,3-thiazol-4-yl)-5-hydroxy-5-oxopent-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-5-hydroxy-5-oxopent-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-[[2-(2-amino-1,3-thiazol-4-yl)-5-hydroxy-5-oxopent-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7432-S
7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-3,4-didehydrocepham-4-carboxylic acid
97519-39-6
97519-40-9
AC1L1E5W
AC1L44AE
AC1NQY0W
AC1NQZPP
AC1O44MA
AC1O4QO4
AKOS005146205
Antibiotic 7432S
BIDD:GT0855
BSPBio_002733
C08117
C15H14N4O6S2
CETB
CHEBI:3510
CHEMBL1605
CID178967
CID2654
CID5281102
CID5282242
CID6375005
CID6398762
Cedax
Ceftem
Ceftibuten (USAN/INN)
Ceftibuten [USAN:INN:BAN]
Ceftibutene
Ceftibutene [INN-French]
 
Ceftibuteno
Ceftibuteno [INN-Spanish]
Ceftibutenum
Ceftibutenum [INN-Latin]
Cephalosporin 7432-S
Cephem
Ceprifran
D00922
DB01415
HMS1922L17
HMS2093K18
Isocef
KBio2_002285
KBio2_004853
KBio2_007421
KBio3_001953
KBioGR_001649
KBioSS_002287
Keimax
LS-149976
LS-187379
MolPort-003-666-607
NCGC00095137-01
NCGC00095137-02
NCGC00178501-01
S 7432
SPBio_001608
SPECTRUM1505207
Sch 39720
Sch-39720
Spectrum2_001684
Spectrum3_001007
Spectrum4_001135
Spectrum5_001558
Spectrum_001794
UNII-IW71N46B4Y
ceftibuten
cis-Ceftibuten
cis-Ceftibutin
cis-ceftibuten
trans-Ceftibuten
40Liver ExtractsPhase 34067
41Penicillanic AcidPhase 3, Phase 274
42Avibactam, ceftazidime drug combinationPhase 315
43CephalosporinsPhase 3, Phase 2168
44beta-Lactamase InhibitorsPhase 3, Phase 2294
45ThienamycinsPhase 356
46Piperacillin, tazobactam drug combinationPhase 3, Phase 283
47carnitineNutraceuticalPhase 3162
48Omega 3 Fatty AcidNutraceuticalPhase 31018
49
Acetylcysteineapproved, investigationalPhase 2330616-91-112035
Synonyms:
(2R)-2-acetylamino-3-sulfanylpropanoic acid
(R)-2-acetylamino-3-mercaptopropanoic acid
(R)-mercapturic acid
2-Acetylamino-3-mercapto-propionate
2-Acetylamino-3-mercapto-propionic acid
ACC
Acetadote
Acetilcisteina
Acetylcysteine
Acetylcysteinum
Fluimicil Infantil
Fluimucetin
Fluimucil
Flumucetin
Fluprowit
 
L-Acetylcysteine
L-acetylcysteine
L-α-acetamido-β-mercaptopropionic acid
Lysox
Mercapturic acid
Mucolysin
Mucomyst
N-Acety-L-Cysteine
N-Acetyl-3-mercaptoalanine
N-Acetyl-L-(+)-cysteine
N-Acetylcysteine
N-acetyl-L-(+)-cysteine
N-acetyl-L-cysteine
N-acetylcysteine
NAC
Parvolex
Sodium 2-acetamido-3-mercaptopropionate
50
CilastatinapprovedPhase 23082009-34-55280454, 6435415
Synonyms:
(2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid
(L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid
(Z)-(S)-6-Carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine
(Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine
(Z)-7-((R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid
(Z)-7-[(2R)-2-amino-3-hydroxy-3-oxopropyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid
81129-83-1 (mono-hydrochloride salt)
82009-34-5
AC-268
AC1O5JQX
BIDD:GT0782
C01675
C16H26N2O5S
CHEBI:3697
CHEMBL766
CID6435415
Cilastatin
Cilastatin (INN)
 
Cilastatin Monosodium Salt
Cilastatin [INN:BAN]
Cilastatin acid
Cilastatina
Cilastatina [Spanish]
Cilastatine
Cilastatine [French]
Cilastatinum
Cilastatinum [Latin]
D07698
DB01597
EINECS 279-875-8
LS-74560
MK-791
MK0791
MolPort-003-987-260
NCGC00181346-01
TL8005438
UNII-141A6AMN38

Interventional clinical trials:

(show all 47)
idNameStatusNCT IDPhase
1Treatment of Acute Pyelonephritis With Gram Negative Strains in Infants and Children Less Than 3 Years OldCompletedNCT00136656Phase 4
2Treatment's Duration of Acute Uncomplicated PyelonephritisCompletedNCT00873626Phase 4
3A Randomized Controlled Trial on Antibiotic Prophylaxis in Children With Vesico-Ureteral RefluxCompletedNCT00382343Phase 4
4Febrile Urinary Tract Infection Randomized Short Treatment TrialCompletedNCT00809913Phase 4
5Efficacy and Safety Study of Short-term Antibiotic for Pyelonephritis in WomenCompletedNCT01390623Phase 4
6Impact of Six Patient Information Leaflets (PIL) on Doctor Patient CommunicationCompletedNCT02246361Phase 4
7Study To Evaluate The Efficacy And Safety Of Ciprofloxacin Extended-Release (Cipro® XR) 1000 mg Tablets Given Once Daily For 7 To 14 Days In The Treatment Of Patients 18 Years Or Older With Complicated Urinary Tract Infections Caused By Pseudomonas AerugiCompletedNCT00481689Phase 4
8Impact on the Intestinal Microbiota of Treatment With Ceftriaxone in Women's Acute Community PyelonephritisNot yet recruitingNCT03179384Phase 4
9Safety and Efficacy Study of the Treatment of Kidney Infections With Short Course LevofloxacinTerminatedNCT00239161Phase 4
10L-carnitine on the Prevention of Renal Scarring in Acute PyelonephritisUnknown statusNCT02007889Phase 3
11Oral Omega-3 for Reduction of Kidney Scar Due to Pyelonephritis in ChildrenUnknown statusNCT02192580Phase 3
12Contrast-Enhanced US of Spleen, Liver and KidneyUnknown statusNCT00190281Phase 3
13Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)CompletedNCT01599806Phase 3
14Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)CompletedNCT01595438Phase 3
15A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP)CompletedNCT02486627Phase 3
16A Comparison of the Effectiveness and Safety of Levofloxacin to That of Ciprofloxacin in Treating Complicated Urinary Tract Infection and Acute Pyelonephritis.CompletedNCT00210886Phase 3
17Efficacy, Safety, Tolerability of Carbavance Compared to Piperacillin/Tazobactam in Complicated Urinary Tract Infections (cUTIs), Including Acute Pyelonephritis (AP), in AdultsCompletedNCT02166476Phase 3
18A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE)CompletedNCT01970371Phase 3
19Efficacy, Safety, Tolerability of Carbavance Compared to Best Available Therapy in Serious Infections Due to Carbapenem Resistant Enterobacteriaceae, in AdultsRecruitingNCT02168946Phase 3
20Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP InfectionsActive, not recruitingNCT02753946Phase 2, Phase 3
21Short-term Antibiotic Therapy for Pyelonephritis in ChildhoodTerminatedNCT00724256Phase 3
22Study of Plazomicin (ACHN-490) Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection and Acute PyelonephritisCompletedNCT01096849Phase 2
23Effect of Acetylcysteine in Pediatric Acute Pyelonephritis.CompletedNCT02080182Phase 2
24Finafloxacin for the Treatment of cUTI and/or Acute PyelonephritisCompletedNCT01928433Phase 2
25Comparative Study of Coadministered Ceftaroline Fosamil and NXL104 vs. Intravenous Doripenem in Adult Subjects With Complicated Urinary Tract InfectionsCompletedNCT01281462Phase 2
26A Study of Efficacy/Safety of Intravenous S-649266 Versus Imipenem/Cilastatin in Complicated Urinary Tract InfectionsCompletedNCT02321800Phase 2
27Sitafloxacin and Ertapenem Treatment for Acute Pyelonephritis Caused by Escherichia ColiRecruitingNCT02537847Phase 2
28Prospective Study in the EmergencyTerminatedNCT01628900Phase 2
29GSK2251052 in Complicated Urinary Tract InfectionTerminatedNCT01381549Phase 2
30Dexamethasone Administration in 1st Episode of Febrile Urinary Tract InfectionUnknown statusNCT02034851
31Urinary Cytokine Levels as a Prognostic Marker for Kidney Scarring After PyelonephritisUnknown statusNCT00868270
32Community-Associated Uropathogen Antimicrobial Resistance Among Emergency Department Patients With Acute PyelonephritisCompletedNCT01641029
33Kinetics of Biomarkers in Acute PyelonephritisCompletedNCT00805181
34Prospective Comparative Study About Treatment of Asymptomatic Bacteriuria in Kidney Transplant Recipients.CompletedNCT02373085
35Study of Cases of Serious Infections Due to Carbapenem-Resistant EnterobacteriaceaeCompletedNCT02420366
36Epidemiology of Acute Bacterial Uncomplicated Cystitis in General PracticeCompletedNCT00958295
37Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Children in the Paediatric A&E.CompletedNCT01396798
38Histology of Implantation Biopsies and Kidney Allograft OutcomesCompletedNCT03155763
39Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary CareCompletedNCT02024282
40Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media)CompletedNCT01406275
41Antibiotic Education for Children in an Emergency Care UnitCompletedNCT00948779
42Prognostic Indicators as Provided by the EPIC ClearViewCompletedNCT01476995
43Proteinuria During Acute Pyelonephritis In PregnancyRecruitingNCT02536638
44Cranberry-lingonberry Juice Started During Acute Infection in Prevention of Urinary Tract Infections in ChildrenRecruitingNCT01861353
45Efficacy and Pharmacokinetic/Pharmacodynamic Parameters of Cefoxitin in Women With Acute Pyelonephritis Without Severity Symptoms Due to Extended-spectrum β-lactamase Producing Escherichia ColiTerminatedNCT01820793
46Urell and PregnancyTerminatedNCT01818180
47Bacterial and Host Genetic Risk Factors in Acute PyelonephritisWithdrawnNCT01137929

Search NIH Clinical Center for Acute Pyelonephritis

Genetic Tests for Acute Pyelonephritis

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Anatomical Context for Acute Pyelonephritis

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MalaCards organs/tissues related to Acute Pyelonephritis:

36
Kidney, Neutrophil, Testes, Prostate, Liver, Colon, Endothelial

Publications for Acute Pyelonephritis

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Articles related to Acute Pyelonephritis:

(show top 50)    (show all 592)
idTitleAuthorsYear
1
Plasmatic presepsin (sCD14-ST) concentrations in acute pyelonephritis in adult patients. (27889429)
2017
2
18F-FDG PET/CT in Renal Infections: Evidence of Acute Pyelonephritis in a Horseshoe Kidney. (27879491)
2017
3
Eliciting renal tenderness by sonopalpation in diagnosing acute pyelonephritis. (28050884)
2017
4
Multiple Renal Abscesses due to ESBL Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Causing Acute Pyelonephritis and Bacteremia: A Case Report with a Good Outcome (No Drainage Required). (28018690)
2016
5
Are the unenhanced and excretory CT phases necessary for the evaluation of acute pyelonephritis? (27563103)
2016
6
Acute pyelonephritis in transplanted kidneys: can diffusion-weighted magnetic resonance imaging be useful for diagnosis and follow-up? (27039324)
2016
7
Acute pyelonephritis resulting in intense vascular blush during dynamic renal scintigraphy. (26917903)
2016
8
Acute Pyelonephritis with Bacteremia Caused by Enterococcus hirae: A Rare Infection in Humans. (27127665)
2016
9
Health care-associated acute pyelonephritis is associated with inappropriate empiric antibiotic therapy in the ED. (27130586)
2016
10
Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population-Based Case-Control Study in Taiwan. (27539679)
2016
11
Reverse kinetics of angiopoietin-2 and endotoxins in acute pyelonephritis: Implications for anti-inflammatory treatment? (26844659)
2016
12
Diagnostic performance of initial serum lactate for predicting bacteremia in female patients with acute pyelonephritis. (27133532)
2016
13
Renal tuberculosis presenting as acute pyelonephritis - A rarity. (27865246)
2016
14
The gender specific risk factors for prolonged hospitalization due to acute pyelonephritis in a Japanese tertiary emergency center. (26712583)
2016
15
Use of cefuroxime for women with community-onset acute pyelonephritis caused by cefuroxime-susceptible or -resistant Escherichia coli. (26767868)
2016
16
Author's reply to the letter to the editor regarding "Hemoglobin level is a more predictive diagnostic marker for acute pyelonephritis than mean platelet volume". (27116249)
2016
17
Usefulness of analytical parameters in the management of paediatric patients with suspicion of acute pyelonephritis. Is procalcitonin reliable? (27329559)
2016
18
Ceftazidime-avibactam Versus Doripenem for the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis: RECAPTURE, a Phase 3 Randomized Trial Program. (27313268)
2016
19
Hemoglobin level is a more predictive diagnostic marker for acute pyelonephritis than mean platelet volume. (26868147)
2016
20
AJKD Atlas of Renal Pathology: Acute Pyelonephritis. (27664480)
2016
21
Outpatient treatment in women with acute pyelonephritis after visiting emergency department. (27534596)
2016
22
Predictive Accuracy of Urinary neutrophil gelatinase associated lipocalin (NGAL) for renal parenchymal involvement in Children with Acute Pyelonephritis. (27053998)
2016
23
Are first-generation cephalosporins obsolete? A retrospective, non-inferiority, cohort study comparing empirical therapy with cefazolin versus ceftriaxone for acute pyelonephritis in hospitalized patients. (26983859)
2016
24
Exploiting the antivirulence efficacy of an ajoene-ciprofloxacin combination against Pseudomonas aeruginosa biofilm associated murine acute pyelonephritis. (26930141)
2016
25
Association between Elevated Alanine Aminotransferase and Urosepsis in Children with Acute Pyelonephritis. (27066449)
2016
26
Evaluation of the efficacy and tolerance of a short 7 day third-generation cephalosporin treatment in the management of acute pyelonephritis in young women in the emergency department. (26903277)
2016
27
Plasma neutrophil gelatinase-associated lipocalin: a marker of acute pyelonephritis in children. (27744618)
2016
28
Validity of Neutrophil Gelatinase Associated Lipocaline as a Biomarker for Diagnosis of Children with Acute Pyelonephritis. (27734430)
2016
29
Acute focal bacterial nephritis in a cohort of hospitalized adult patients with acute pyelonephritis. Assessment of risk factors and a predictive model. (27986362)
2016
30
Retrospective Comparison of Clinical Characteristics and In-Hospital Outcomes among Diabetic and Non-Diabetic Adults with Acute Pyelonephritis. (27891373)
2016
31
Development of Epidural and Paraspinal Abscesses after Insufficient Evaluation and Treatment of Acute Pyelonephritis Caused by Staphylococcus aureus. (27688864)
2016
32
A Case of Acute Pyelonephritis in Bilateral Renal Malrotation. (27689034)
2016
33
Urachal abscess precipitated as acute pyelonephritis in an adult patient with diabetes. (26813570)
2016
34
Acute pyelonephritis and renal vein thrombosis: A case report and review of the literature. (27234357)
2016
35
Recurrent obstructive acute pyelonephritis: A rare form of Actinobaculum schaalii infection in a HIV-1 infected patient. (27940245)
2016
36
The combination of urinary IL - 6 and renal biometry as useful diagnostic tools to differentiate acute pyelonephritis from lower urinary tract infection. (27564295)
2016
37
Comparison of computed tomography findings between bacteremic and non-bacteremic acute pyelonephritis due to Escherichia coli. (27158427)
2016
38
Adult Idiopathic Renal Vein Thrombosis Mimicking Acute Pyelonephritis. (27790518)
2016
39
Core curriculum illustration: acute pyelonephritis. (28032258)
2016
40
Impact of Extended-Spectrum I^-Lactamase Production on Treatment Outcomes of Acute Pyelonephritis Caused by Escherichia coli in Patients without Health Care-Associated Risk Factors. (25583722)
2015
41
Vitamin e as adjuvant treatment for urinary tract infection in girls with acute pyelonephritis. (25851287)
2015
42
Effect of N-Acetylcysteine on Inflammation Biomarkers in Pediatric Acute Pyelonephritis: a Randomized Controlled Trial. (26552352)
2015
43
The evidence for treating acute pyelonephritis with oral antibiotic therapy and short intravenous treatment is growing for low-risk children. (25736044)
2015
44
Megalocytic interstitial nephritis following acute pyelonephritis with Escherichia coli bacteremia: a case report. (25552891)
2015
45
A comparison of the clinical characteristics of elderly and non-elderly women with community-onset, non-obstructive acute pyelonephritis. (25995668)
2015
46
Erratum: Intrathoracic kidney with left-sided Bochdalek hernia in a woman with bacteremic acute pyelonephritis due to Escherichia coli. (25995678)
2015
47
Differentiation of acute pyelonephritis from other febrile states in children using urinary neutrophil gelatinase-associated lipocalin (uNGAL). (26053013)
2015
48
Urinary neutrophil gelatinase-associated lipocalin (NGAL) might be an independent marker for anticipating scar formation in children with acute pyelonephritis. (26060836)
2015
49
Intrathoracic kidney with left-sided Bochdalek hernia in a woman with bacteremic acute pyelonephritis due to Escherichia coli. (25750574)
2015
50
Propensity-Matched Analysis To Compare the Therapeutic Efficacies of Cefuroxime versus Cefotaxime as Initial Antimicrobial Therapy for Community-Onset Complicated Nonobstructive Acute Pyelonephritis Due to Enterobacteriaceae Infection in Women. (25645837)
2015

Variations for Acute Pyelonephritis

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Expression for genes affiliated with Acute Pyelonephritis

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Search GEO for disease gene expression data for Acute Pyelonephritis.

Pathways for genes affiliated with Acute Pyelonephritis

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Pathways related to Acute Pyelonephritis according to GeneCards Suite gene sharing:

(show all 16)
idSuper pathwaysScoreTop Affiliating Genes
19.6IL10, IL6
29.5CRP, CXCL8, IL6
39.5CXCL8, CXCR1, IL6
49.2CXCL10, CXCL8, IL6
5
Show member pathways
9.2CXCL10, CXCL8, IL6
6
Show member pathways
9.2CXCL8, IL10, IL6
79.2CXCL8, IL10, IL6
89.2CXCL8, IL10, IL6
99.2CXCL8, IL10, IL6
109.2CXCL8, IL10, IL6
119.2CXCL8, IL10, IL6
12
Show member pathways
8.9CXCL10, CXCL8, CXCR1, CXCR2
138.7CXCL10, CXCL8, IL10, IL6
148.7CXCL10, CXCL8, IL10, IL6
15
Show member pathways
7.1CXCL10, CXCL8, CXCR1, CXCR2, IL10, IL6
16
Show member pathways
7.1CXCL10, CXCL8, CXCR1, CXCR2, IL10, IL6

GO Terms for genes affiliated with Acute Pyelonephritis

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Cellular components related to Acute Pyelonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.3ADM, ALB, CRP, CXCL10, CXCL8, IL10
2extracellular spaceGO:00056156.6ADM, ALB, CRP, CXCL10, CXCL8, IL10

Biological processes related to Acute Pyelonephritis according to GeneCards Suite gene sharing:

(show all 26)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of lipid storageGO:001088810.5CRP, IL6
2dendritic cell chemotaxisGO:000240710.5CXCR1, CXCR2
3interleukin-8-mediated signaling pathwayGO:003811210.4CXCR1, CXCR2
4neutrophil activationGO:004211910.4CXCL8, CXCR2
5cellular response to hepatocyte growth factor stimulusGO:003572910.3IL10, IL6
6defense response to protozoanGO:004283210.3IL10, IL6
7response to auditory stimulusGO:001099610.2CXCL10, IL6
8branching involved in labyrinthine layer morphogenesisGO:006067010.1ADM, IL10
9induction of positive chemotaxisGO:005093010.0CXCL8, PGF
10defense response to Gram-positive bacteriumGO:00508309.9ADM, CRP, IL6
11agingGO:00075689.7ADM, IL10, IL6
12chemokine-mediated signaling pathwayGO:00700989.6CXCL10, CXCL8, CXCR1, CXCR2
13response to molecule of bacterial originGO:00022379.6CXCL8, IL10
14chemotaxisGO:00069359.6CXCL10, CXCL8, CXCR1, CXCR2
15response to coldGO:00094099.6ADM, CXCL10, IL6
16response to glucocorticoidGO:00513849.6ADM, IL10, IL6
17response to insulinGO:00328689.5ADM, IL10, IL6
18cellular response to lipopolysaccharideGO:00712229.5CXCL10, CXCL8, IL10, IL6
19immune responseGO:00069559.5CXCL10, CXCL8, IL10, IL6
20receptor internalizationGO:00316239.4ADM, CXCL8, CXCR1, CXCR2
21positive regulation of angiogenesisGO:00457669.4ADM, CXCL8, PGF
22negative regulation of cell proliferationGO:00082859.3ADM, CXCL8, IL10, IL6
23cell-cell signalingGO:00072678.7ADM, CXCL10, IL10, PGF
24response to lipopolysaccharideGO:00324968.7ADM, CXCL10, IL10, IL6
25inflammatory responseGO:00069548.4CRP, CXCL10, CXCL8, CXCR1, CXCR2, IL10
26positive regulation of cell proliferationGO:00082848.3ADM, CXCL10, CXCR2, IL6, PGF

Molecular functions related to Acute Pyelonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1C-X-C chemokine receptor activityGO:001649410.4CXCR1, CXCR2
2interleukin-8 receptor activityGO:00049189.7CXCR1, CXCR2
3interleukin-8 bindingGO:00199599.6CXCR1, CXCR2
4cytokine activityGO:00051259.3CXCL10, CXCL8, IL10, IL6
5growth factor activityGO:00080838.9IL10, IL6, PGF

Sources for Acute Pyelonephritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet