Aliases & Classifications for Acute Pyelonephritis

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Aliases & Descriptions for Acute Pyelonephritis:

Name: Acute Pyelonephritis 8 44 61
 
Acute Pyelonephritis Nos 8


External Ids:

Disease Ontology8 DOID:559
ICD9CM27 590.1

Summaries for Acute Pyelonephritis

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MalaCards based summary: Acute Pyelonephritis, also known as acute pyelonephritis nos, is related to pyelonephritis and bacteriuria. An important gene associated with Acute Pyelonephritis is CXCR1 (chemokine (C-X-C motif) receptor 1), and among its related pathways are Carbon metabolism and Glycolysis and gluconeogenesis short map . The compounds 99mtc-dmsa and dmsa have been mentioned in the context of this disorder. Affiliated tissues include kidney, neutrophil and testes.

Related Diseases for Acute Pyelonephritis

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Diseases in the Pyelonephritis family:

acute pyelonephritis Chronic Pyelonephritis

Diseases related to Acute Pyelonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 73)
idRelated DiseaseScoreTop Affiliating Genes
1pyelonephritis32.1CXCR1, CRP, NAGLU
2bacteriuria31.3CRP
3hydronephrosis30.9NAGLU
4pneumonia30.1NAGLU, CRP
5rheumatoid arthritis30.0NAGLU, CXCR1, CRP
6vesicoureteral reflux10.5
7bacteremia10.5
8cystitis10.5
9blindness10.5
10gallbladder disease10.4GOT1
11metabolic acidosis10.3AQP2
12vascular disease10.2GOT1
13adult respiratory distress syndrome10.2
14arthritis10.2
15acute cystitis10.2
16interstitial nephritis10.2
17osteomyelitis10.2
18prostatitis10.2
19nephritis10.2
20exanthem10.2GOT1, CRP
21pulmonary disease, chronic obstructive10.2CXCR1, CRP
22leukopenia10.1GOT1, CRP
23fatty liver disease10.1CRP, GOT1
24diarrhea10.1GOT1, CRP
25acute myocardial infarction10.1NAGLU, CRP
26pancreatitis10.1GOT1, CRP
27liver disease10.1CRP, GOT1
28proteinuria10.1CRP, NAGLU
29hypertension, essential10.1AQP2, NAGLU
30microvascular complications of diabetes 310.1AQP2, NAGLU
31primary hyperoxaluria10.0NAGLU, AQP2
32kawasaki disease10.0
33glomerulonephritis10.0
34hepatitis10.0
35nephrolithiasis10.0
36pseudohypoaldosteronism10.0
37spinal cord injury10.0
38thrombocytopenia10.0
39anuria10.0
40perinephritis10.0
41renal fibrosis10.0
42melioidosis10.0
43carbuncle10.0
44splenic abscess10.0
45hyperhomocysteinemia10.0
46ureterocele10.0
47pyomyositis10.0
48septic arthritis10.0
49epidural abscess10.0
50subacute glomerulonephritis10.0

Graphical network of the top 20 diseases related to Acute Pyelonephritis:



Diseases related to acute pyelonephritis

Symptoms for Acute Pyelonephritis

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Drugs & Therapeutics for Acute Pyelonephritis

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Drug clinical trials:

Search ClinicalTrials for Acute Pyelonephritis

Search NIH Clinical Center for Acute Pyelonephritis

Genetic Tests for Acute Pyelonephritis

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Anatomical Context for Acute Pyelonephritis

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MalaCards organs/tissues related to Acute Pyelonephritis:

31
Kidney, Neutrophil, Testes, Colon, Liver, Prostate, Whole blood, Cortex, Spinal cord, Thyroid, B cells, Endothelial

Animal Models for Acute Pyelonephritis or affiliated genes

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Publications for Acute Pyelonephritis

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Articles related to Acute Pyelonephritis:

(show top 50)    (show all 539)
idTitleAuthorsYear
1
Oral penicillin-associated acute kidney injury in an infant with acute pyelonephritis. (25711153)
2015
2
The efficacy of non-carbapenem antibiotics for the treatment of community-onset acute pyelonephritis due to extended-spectrum I^-lactamase-producing Escherichia coli. (24928854)
2014
3
Are serum procalcitonin and interleukin-1 beta suitable markers for diagnosis of acute pyelonephritis in children? (24874931)
2014
4
Is the mean platelet volume a predictive marker for the diagnosis of acute pyelonephritis in children? (25367868)
2014
5
Effects of Gentamicin Monotherapy for the Initial Treatment of Community-Onset Complicated Non-Obstructive Acute Pyelonephritis Due to Enterobacteriaceae in Elderly and Non-Elderly Women. (24909648)
2014
6
The first case of atrial fibrillation-related graft kidney infarction following acute pyelonephritis. (24694493)
2014
7
Acute pyelonephritis in diabetes mellitus: Single center experience. (25484530)
2014
8
Urinary concentration of cytokines in children with acute pyelonephritis. (23389820)
2013
9
The effect of vitamin E or vitamin A on the prevention of renal scarring in children with acute pyelonephritis. (23052650)
2013
10
Enterococcus hirae-related acute pyelonephritis and cholangitis with bacteremia: an unusual infection in humans. (22313539)
2012
11
The influence of chronic renal failure on the spectrum and antimicrobial susceptibility of uropathogens in community-acquired acute pyelonephritis presenting as a positive urine culture. (21507269)
2011
12
Selection of first-line i.v. antibiotics for acute pyelonephritis in patients requiring emergency hospital admission. (20839025)
2011
13
A simple model to predict bacteremia in women with acute pyelonephritis. (21722666)
2011
14
Comparison of extended virulence genotypes for bacteria isolated from pediatric patients with urosepsis, acute pyelonephritis, and acute lobar nephronia. (20661102)
2010
15
Antibiotics for acute pyelonephritis in children. (17943796)
2007
16
Association between mannose-binding lectin deficiency and septic shock following acute pyelonephritis due to Escherichia coli. (17202308)
2007
17
Maternal serum concentrations of the chemokine CXCL10/IP-10 are elevated in acute pyelonephritis during pregnancy. (17763275)
2007
18
Maternal serum soluble CD30 is increased in pregnancies complicated with acute pyelonephritis. (17853184)
2007
19
Oestroprogestagens and severe acute pyelonephritis: a casual or causal association? (16868038)
2006
20
Accurate diagnosis of acute pyelonephritis: How helpful is procalcitonin? (16894326)
2006
21
Clarithromycin: immunomodulatory therapy of experimental sepsis and acute pyelonephritis by Escherichia coli. (15764190)
2005
22
Immunomodulatory clarithromycin treatment of experimental sepsis and acute pyelonephritis caused by multidrug-resistant Pseudomonas aeruginosa. (14693524)
2004
23
Treatment of acute pyelonephritis in children. (14739166)
2004
24
Acute pyelonephritis: analysis of 52 cases. (12380905)
2002
25
Follow-up of acute pyelonephritis in children by Tc-99m DMSA scintigraphy: quantitative and qualitative assessment. (11317023)
2001
26
Hospitalization for acute pyelonephritis in Manitoba, Canada, during the period from 1989 to 1992; impact of diabetes, pregnancy, and aboriginal origin. (8783709)
1996
27
Prospective, randomized, controlled study comparing two dosing regimens of gentamicin/oral ciprofloxacin switch therapy for acute pyelonephritis. (8879853)
1996
28
Treatment trials on children with acute pyelonephritis. (7917850)
1994
29
Duration of antimicrobial treatment and the use of drug combinations for the treatment of uncomplicated acute pyelonephritis. (8050796)
1994
30
Functional parameters and 99mtechnetium-dimercaptosuccinic acid scan in acute pyelonephritis. (7696107)
1994
31
Vesicoureteral reflux: an accurate predictor of acute pyelonephritis in childhood urinary tract infection? (8284391)
1994
32
Sexual acquisition of acute pyelonephritis in a man. (8460339)
1993
33
The sensitivity of renal scintigraphy and sonography in detecting nonobstructive acute pyelonephritis. (1640534)
1992
34
Comparison of ciprofloxacin with netilmicin for the treatment of acute pyelonephritis. (1553112)
1992
35
Diagnosis of acute pyelonephritis in children: comparison of sonography and 99mTc-DMSA scintigraphy. (1651644)
1991
36
Attenuation of antibody response to acute pyelonephritis by treatment with antibiotics. (1804007)
1991
37
Long-term risks of acute pyelonephritis. (2179757)
1990
38
Special virulence of the Escherichia coli O1:K1:H7 clone in acute pyelonephritis. (2661790)
1989
39
Acute pyelonephritis in pregnancy at Ramathibodi Hospital: a descriptive epidemiological study. (3183551)
1988
40
The intravenous pyelogram in acute pyelonephritis. (3052346)
1988
41
The characteristics and hospital course of patients admitted for presumed acute pyelonephritis. (3543268)
1987
42
Acute pyelonephritis in pregnancy. (3791931)
1986
43
Urinary immunoglobulins in healthy individuals and children with acute pyelonephritis. (3890147)
1985
44
Urinary tract infection during pregnancy. Asymptomatic bacteriuria, acute cystitis, and acute pyelonephritis. (6374641)
1984
45
Acute pyelonephritis in the elderly. (7079812)
1982
46
Bacteria-specific antibody in the urine of patients with acute pyelonephritis and cystitis. (7014730)
1981
47
A clinical approach to the choice of antimicrobial agents. Case number 13: acute pyelonephritis. (7351516)
1980
48
Gallium-67 radionuclide imaging in acute pyelonephritis. (6766013)
1980
49
An ultrastructural study of the renal medulla in experimental acute pyelonephritis. (1099824)
1975
50
CLINICAL pathologic conference: acute and subacute glomerulonephritis with acute pyelonephritis. (13061782)
1953

Variations for Acute Pyelonephritis

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Expression for genes affiliated with Acute Pyelonephritis

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Search GEO for disease gene expression data for Acute Pyelonephritis.

Pathways for genes affiliated with Acute Pyelonephritis

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Pathways related to Acute Pyelonephritis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
L-serine degradation36
pentose phosphate pathway (oxidative branch)36
formaldehyde oxidation II (glutathione-dependent)36
9.1FBP1, GOT1
2
Show member pathways
glycolysis36
gluconeogenesis36
Glycolysis and Gluconeogenesis36
9.1FBP1, GOT1
3
Show member pathways
malate-aspartate shuttle36
glycogen biosynthesis II (from UDP-D-Glucose)36
9.1FBP1, GOT1
4
Show member pathways
8.7NAGLU, FBP1, GOT1

Compounds for genes affiliated with Acute Pyelonephritis

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Compounds related to Acute Pyelonephritis according to GeneCards Suite gene sharing:

(show all 31)
idCompoundScoreTop Affiliating Genes
199mtc-dmsa449.9CRP, NAGLU
2dmsa449.9NAGLU, CRP
3perindopril44 50 1111.9CRP, NAGLU
4c-peptide449.8NAGLU, CRP
5neopterin449.8CRP, NAGLU
6malondialdehyde449.8NAGLU, CRP
7losartan44 50 28 1112.8NAGLU, CRP
8uric acid44 2410.8CRP, NAGLU
9latex449.8CRP, NAGLU
10mercury449.8NAGLU, AQP2
11desmopressin44 60 28 1112.8NAGLU, AQP2
12homocysteine44 2410.8NAGLU, CRP
13furosemide44 60 28 50 24 1114.8AQP2, NAGLU
14mannitol44 1110.7NAGLU, CRP
15lithium44 50 24 1112.7NAGLU, AQP2
16hydrochlorothiazide44 28 50 24 1113.7AQP2, CRP
17citrate449.6CRP, NAGLU
18biotin44 24 1111.6AQP2, CRP
19cytochalasin d44 6010.6AQP2, CXCR1
20urea44 24 1111.6AQP2, NAGLU
21cyclophosphamide44 50 1111.6NAGLU, CRP
22endotoxin449.5CXCR1, CRP
23vitamin a44 24 1111.5CRP, NAGLU
24creatinine449.2CRP, NAGLU, AQP2
25alanine449.1CRP, NAGLU, AQP2
26folate449.0CRP, FBP1
27Water248.9FBP1, AQP2, NAGLU
28lipid448.8AQP2, NAGLU, CXCR1, CRP
29cysteine448.7NAGLU, CXCR1, AQP2
30calcium44 50 24 1111.7CXCR1, NAGLU, AQP2, CRP
31glucose448.4CRP, NAGLU, FBP1, AQP2

GO Terms for genes affiliated with Acute Pyelonephritis

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Cellular components related to Acute Pyelonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lysosomeGO:00057648.6NAGLU, AQP2, GOT1
2extracellular vesicular exosomeGO:00700628.1NAGLU, AQP2, FBP1, GOT1

Biological processes related to Acute Pyelonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glucose metabolic processGO:00060069.1FBP1, GOT1
2agingGO:00075689.0CRP, AQP2
3gluconeogenesisGO:00060949.0FBP1, GOT1
4carbohydrate metabolic processGO:00059758.7NAGLU, FBP1, GOT1

Sources for Acute Pyelonephritis

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet