ALI
MCID: ACT210
MIFTS: 57

Acute Respiratory Distress Syndrome (ALI) malady

Categories: Rare diseases, Respiratory diseases, Cardiovascular diseases

Aliases & Classifications for Acute Respiratory Distress Syndrome

Aliases & Descriptions for Acute Respiratory Distress Syndrome:

Name: Acute Respiratory Distress Syndrome 50
Respiratory Distress Syndrome, Adult 50 69
Non-Cardiogenic Pulmonary Edema 50 69
Acute Respiratory Distress 52 69
Acute Lung Injury 50 56
Increased-Permeability Pulmonary Edema 50
Adult Respiratory Distress Syndrome 50
Respiratory Distress Syndrome Adult 52
Shock Lung 50
Stiff Lung 50
Ards 50
Ali 50

Characteristics:

Orphanet epidemiological data:

56
acute lung injury
Prevalence: 1-5/10000 (Europe);

Classifications:

Orphanet: 56  
Rare respiratory diseases


External Ids:

Orphanet 56 ORPHA178320
MESH via Orphanet 43 D055371
UMLS via Orphanet 70 C0242488

Summaries for Acute Respiratory Distress Syndrome

NIH Rare Diseases : 50 acute respiratory distress syndrome (ards) is a life-threatening lung condition that prevents enough oxygen from getting to the lungs and into the blood.  people who develop ards often are very ill with another disease or have major injuries. the condition leads to a buildup of fluid in the air sacs which prevents enough oxygen from passing into the bloodstream. symptoms may include difficulty breathing, low blood pressure and organ failure, rapid breathing and shortness of breath. last updated: 5/17/2012

MalaCards based summary : Acute Respiratory Distress Syndrome, also known as respiratory distress syndrome, adult, is related to acute cor pulmonale and pulmonary tuberculosis, and has symptoms including cheyne-stokes respiration, coughing and dyspnea. An important gene associated with Acute Respiratory Distress Syndrome is ELANE (Elastase, Neutrophil Expressed), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and Toll Comparative Pathway. The drugs Curosurf and Infasurf have been mentioned in the context of this disorder. Affiliated tissues include lung, neutrophil and endothelial, and related phenotypes are immune system and liver/biliary system

Wikipedia : 71 Acute (or Adult) respiratory distress syndrome (ARDS) is a medical condition occurring in critically ill... more...

Related Diseases for Acute Respiratory Distress Syndrome

Diseases in the Adult Respiratory Distress Syndrome family:

Acute Respiratory Distress Syndrome Adult Acute Respiratory Distress Syndrome

Diseases related to Acute Respiratory Distress Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 267)
id Related Disease Score Top Affiliating Genes
1 acute cor pulmonale 30.4 ELANE IL6 PI3
2 pulmonary tuberculosis 30.0 CXCL8 IL6 TNF
3 pyoderma gangrenosum 29.8 CXCL8 IL6 TNF
4 neuropathy 29.6 CXCL8 IL6 PLA2G7 TNF
5 adult acute respiratory distress syndrome 12.2
6 refsum disease 11.5
7 respiratory distress syndrome in premature infants 11.1
8 pulmonary fibrosis, idiopathic 11.0
9 aspiration pneumonitis 10.8
10 pleural disease 10.8
11 fructose intolerance 10.8
12 aicardi-goutieres syndrome 1, dominant and recessive 10.8
13 al amyloidosis 10.8
14 vps11-related autosomal recessive hypomyelinating leukodystrophy 10.3 IL6 TNF
15 pneumonia 10.3
16 oculomotor nerve paralysis 10.3 CXCL8 IL6
17 common peroneal nerve lesion 10.3 CXCL8 IL6
18 malaria 10.3
19 dyslexia 5 10.3 IL6 TNF
20 aortic atherosclerosis 10.3 IL6 TNF
21 degenerative disc disease 10.2 IL6 TNF
22 tuberculosis 10.2
23 conidiobolomycosis 10.2 CXCL8 TNF
24 trichomalacia 10.2 CXCL8 IL6 TNF
25 cicatricial lagophthalmos 10.2 CXCL8 IL6 TNF
26 gastric dilatation 10.2 CXCL8 IL6 TNF
27 acquired thrombocytopenia 10.2 CXCL8 IL6 TNF
28 autosomal recessive type iv ehlers-danlos syndrome 10.2 CXCL8 IL6 TNF
29 calpainopathy 10.2 CXCL8 ELANE SFTPB
30 erb-duchenne and dejerine-klumpke palsies 10.2 CXCL8 IL6 TNF
31 transverse myelitis 10.2 SFTPB SFTPD
32 inappropriate adh syndrome 10.2 CXCL8 IL6 TNF
33 labyrinthitis 10.2 CXCL8 IL6 TNF
34 atrophy of prostate 10.2 CXCL8 IL6 TNF
35 myiasis 10.2 CXCL8 IL6 TNF
36 blepharochalasis 10.2 CXCL8 IL6 TNF
37 fasciitis 10.2 CXCL8 ELANE TNF
38 choroiditis 10.2 CXCL8 IL6 TNF
39 unilateral multicystic dysplastic kidney 10.2 IL6 TNF
40 depressed scar 10.2 CXCL8 IL6 TNF
41 burns 10.2 CXCL8 IL6 TNF
42 paranasal sinus sarcoma 10.2 CXCL8 IL6 TNF
43 baritosis 10.2 CXCL8 IL6 TNF
44 splenic marginal zone lymphoma 10.2 CXCL8 IL6 TNF
45 colon adenocarcinoma 10.2 CXCL8 IL6 TNF
46 familial renal papillary carcinoma 10.2 CXCL8 ELANE TNF
47 classic type lipoma 10.2 CXCL8 IL6 TNF
48 conjunctival concretion 10.2 CXCL8 IL6 TNF
49 parasitic protozoa infectious disease 10.2 CXCL8 IL6 TNF
50 scrub typhus 10.2

Graphical network of the top 20 diseases related to Acute Respiratory Distress Syndrome:



Diseases related to Acute Respiratory Distress Syndrome

Symptoms & Phenotypes for Acute Respiratory Distress Syndrome

UMLS symptoms related to Acute Respiratory Distress Syndrome:


cheyne-stokes respiration, coughing, dyspnea, hemoptysis, hoarseness, respiratory distress, labored breathing

MGI Mouse Phenotypes related to Acute Respiratory Distress Syndrome:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.81 ELANE IL6 LBP LTA PLA2G7 SFTPC
2 liver/biliary system MP:0005370 9.43 F5 IL6 LBP LTA THBD TNF
3 respiratory system MP:0005388 9.17 IL6 LTA SFTPB SFTPC SFTPD THBD

Drugs & Therapeutics for Acute Respiratory Distress Syndrome

FDA approved drugs:

id Drug Name Active Ingredient(s) 17 Company Approval Date
1
Curosurf 17 PORACTANT ALFA Dey Laboratories Approved October 1998
2
Infasurf 17 CALFACTANT ONY Approved July 1998

Drugs for Acute Respiratory Distress Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 556)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clonidine Approved Phase 4 4205-90-7 2803
2
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1 10102-43-9 145068
3
Zinc Approved Phase 4,Phase 2 7440-66-6 32051 23994
4
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
5
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 1,Phase 2 59467-70-8 4192
6
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Phase 1 103-90-2 1983
7
Metformin Approved Phase 4,Phase 2,Phase 3 657-24-9 14219 4091
8
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
9
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-23-7 5754 657311
10
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2 378-44-9 9782
11
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
12
Budesonide Approved Phase 4,Phase 2 51333-22-3 63006 5281004
13
Remifentanil Approved Phase 4 132875-61-7 60815
14
Ketamine Approved, Vet_approved Phase 4,Phase 3 6740-88-1 3821
15
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
16
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
17
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
18
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
19
Menthol Approved Phase 4,Phase 2,Phase 1 2216-51-5 16666
20
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
21
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
22
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
23 Beractant Approved Phase 4,Phase 2,Phase 3,Phase 1 108778-82-1
24
Povidone-iodine Approved Phase 4,Phase 3,Phase 2 25655-41-8
25 Poractant alfa Approved Phase 4,Phase 3,Phase 2 129069-19-8
26
Carbon monoxide Approved Phase 4,Phase 1 630-08-0 281
27
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
28
Progesterone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 57-83-0 5994
29
Erythromycin Approved, Vet_approved Phase 4 114-07-8 12560
30
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3 57-27-2 5288826
31
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
32
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 76631-46-4, 113775-47-6 68602 5311068 56032
33
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
34
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
35
Fibrinolysin Approved Phase 4,Phase 3,Phase 2 9004-09-5
36
Mechlorethamine Approved Phase 4,Phase 3 51-75-2 4033
37
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 2180-92-9, 38396-39-3 2474
38
Imipenem Approved Phase 4 74431-23-5 104838
39
Colistin Approved Phase 4 1264-72-8, 1066-17-7 5311054
40
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
41
Misoprostol Approved Phase 4 59122-46-2 5282381
42
Tobramycin Approved, Investigational Phase 4 32986-56-4 5496 36294
43
Desflurane Approved Phase 4 57041-67-5 42113
44
Vancomycin Approved Phase 4 1404-90-6 441141 14969
45
Linezolid Approved, Investigational Phase 4 165800-03-3 441401
46
Daptomycin Approved, Investigational Phase 4 103060-53-3 16129629
47 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1
48
Glycine Approved, Nutraceutical, Vet_approved Phase 4,Phase 1,Phase 2 56-40-6 750
49
Butyric Acid Experimental Phase 4,Phase 3,Phase 2 107-92-6 264
50 Cisatracurium Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 1194)
id Name Status NCT ID Phase
1 Effects of Neuromuscular Blocking Agents (NMBA) on the Alteration of Transpulmonary Pressures at the Early Phase of Acute Respiratory Distress Syndrome (ARDS) Unknown status NCT01573715 Phase 4
2 Effect of Treatment With Stress-Doses Glucocorticoid in Patients With Acute Respiratory Distress Syndrome (ARDS) Unknown status NCT00773058 Phase 4
3 The Study of Using Esophageal Pressure to Guide the PEEP Setting in Abdominal Hypertension Patients Who Undergoing Mechanical Ventilation Unknown status NCT01825304 Phase 4
4 Withholding Feeds During Red Blood Cell Transfusion and TRAGI Unknown status NCT02132819 Phase 4
5 Hemostasis in Kocher-Langenbeck Approaches for Acetabular Surgery Using a Topical Surgical Hemostat (Vitagel) Unknown status NCT01230931 Phase 4
6 6-Methyl-Prednisolone for Multiple Organ Dysfunction Syndrome Unknown status NCT00127985 Phase 4
7 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
8 Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure Unknown status NCT01873521 Phase 4
9 FRC Guided Therapy in Acute Respiratory Failure Unknown status NCT01280019 Phase 4
10 Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparations Unknown status NCT01941524 Phase 4
11 Two Strategies of RDS Treatment in Newborns With Birth Weight > 1500 Grams Unknown status NCT00277030 Phase 4
12 Efficacy Evaluation of Surfactant Administration Via Laryngeal Mask Airway Unknown status NCT01173237 Phase 4
13 Propofol Versus Midazolam as Premedication for Preterm Neonates With Respiratory Distress Syndrome (RDS) Unknown status NCT00797160 Phase 4
14 Early CPAP in Respiratory Distress Syndrome Unknown status NCT00368680 Phase 4
15 Prevention of Chronic Lung Disease (CLD) in Preterm Infants Unknown status NCT00883532 Phase 4
16 Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure. Unknown status NCT00331656 Phase 4
17 Normoglycemia and Neurological Outcome Unknown status NCT01137773 Phase 4
18 Surfactant Administration During Spontaneous Breathing Unknown status NCT01329432 Phase 4
19 Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn Unknown status NCT01499238 Phase 4
20 Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in Japan Completed NCT00219375 Phase 4
21 Standard Treatment Compliance of Participants, Effectiveness and Prognosis in Acute Respiratory Distress Syndrome Completed NCT02178982 Phase 4
22 Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) Completed NCT01600651 Phase 4
23 Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study) Completed NCT02166853 Phase 4
24 INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery Completed NCT01020409 Phase 4
25 Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach Completed NCT02135146 Phase 4
26 Inflammatory Response Secondary Using Intravenous Anesthesia Versus Inhalation Anesthesia With Halogenated Agents Completed NCT02168751 Phase 4
27 Steroids in Bilateral Total Knee Replacement Completed NCT01399268 Phase 4
28 Effect of Perioperative Lung Protective Strategies on the Occurrence of Postoperative Pulmonary Complications in Patients Undergoing Lumbar Spinal Surgery in the Prone Position Completed NCT02373475 Phase 4
29 Premedication for Non-Emergency Endotracheal Intubation In the NICU Completed NCT01749501 Phase 4
30 Comparison of Effectiveness of Nasal CPAP and Nasal IMV in Early Rescue Surfactant Treatment in Preterm Infants Completed NCT01741129 Phase 4
31 Non-Positive Pressure Ventilation in Hypoxemic Patients Completed NCT00925860 Phase 4
32 Synchronized Intermittent Mandatory Ventilation (SIMV) Versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) In Preterm Infants With Respiratory Distress Completed NCT00486850 Phase 4
33 Recruitment Maneuver After Intubation Completed NCT01014299 Phase 4
34 Effects of Bolus Surfactant Therapy on Peripheral Perfusion Index and Tissue Carbon Monoxide Completed NCT01923844 Phase 4
35 Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal Intubation Completed NCT01042600 Phase 4
36 Efficacy of Combining Prophylactic Curosurf With Early Nasal CPAP in Delivery Room: the Curpap Study Completed NCT00501982 Phase 4
37 Effect of Combined Remote Ischemic Preconditioning and Postconditioning on Acute Pulmonary Injury in Patients Undergoing Valvular Heart Surgery Completed NCT01427621 Phase 4
38 Intraoperative Protective Ventilation in Abdominal Surgery (IMPROVE Study) Completed NCT01282996 Phase 4
39 Evaluation Of The Total Face Mask For Emergency Application In Acute Respiratory Failure Completed NCT00686257 Phase 4
40 Remifentanil Versus Morphine for Sedation of Premature Neonates With Respiratory Distress Syndrome Completed NCT00391105 Phase 4
41 A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized Trial Completed NCT02009280 Phase 4
42 Safety and Efficacy of Intravenous Tranexamic Acid in Endoscopic Transurethral Resections in Urology Completed NCT02653261 Phase 4
43 Effect of Aerosolised Colistin in Ventilator Associated Pneumonia Completed NCT02683603 Phase 4
44 PROUD Study: A Prospective Study on the Usage Patterns of Doripenem in the Asia Pacific Region Completed NCT00986102 Phase 4
45 Use of Transdermal Clonidine in Trauma Patients Completed NCT01139996 Phase 4
46 Vertebroplasty Compared With a Sham-procedure for Painful Acute Osteoporotic Vertebral Fractures Completed NCT01537770 Phase 4
47 Use of Erythromycin in Mustard-Induced Bronchiolitis Completed NCT00367419 Phase 4
48 The Effect of the Hemobag® Ultrafiltration System on Blood Conservation and Coagulation After Cardiopulmonary Bypass Completed NCT01435304 Phase 4
49 Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication Completed NCT02246361 Phase 4
50 Lumbar Plexus Block Upon the Incidence of Ischemic Cardiovascular Events in Elderly Patients With Hip Fracture Completed NCT01961895 Phase 4

Search NIH Clinical Center for Acute Respiratory Distress Syndrome

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Acute Respiratory Distress Syndrome

Anatomical Context for Acute Respiratory Distress Syndrome

MalaCards organs/tissues related to Acute Respiratory Distress Syndrome:

39
Lung, Neutrophil, Endothelial, Brain, Liver, Monocytes, Kidney

Publications for Acute Respiratory Distress Syndrome

Articles related to Acute Respiratory Distress Syndrome:

(show top 50) (show all 469)
id Title Authors Year
1
Obesity and survival in critically ill patients with acute respiratory distress syndrome: a paradox within the paradox. ( 28532465 )
2017
2
Novel swine model of ricin-induced acute respiratory distress syndrome. ( 28067630 )
2017
3
Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. ( 28062701 )
2017
4
Long-Term Pulmonary Function and Quality of Life in Children After Acute Respiratory Distress Syndrome: A Feasibility Investigation. ( 28060170 )
2017
5
Muscle Weakness and 5-Year Survival in Acute Respiratory Distress Syndrome Survivors. ( 28067712 )
2017
6
Interstitial Lung Abnormalities Are Associated with Acute Respiratory Distress Syndrome. ( 28035861 )
2017
7
CXCL10/IP-10 Neutralization Can Ameliorate Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome in Rats. ( 28046003 )
2017
8
Early Evaluation and Monitoring of Critical Patients with Acute Respiratory Distress Syndrome (ARDS) Using Specific Genetic Polymorphisms. ( 28070694 )
2017
9
The Bumpy Road for Noninvasive Ventilation in Acute Respiratory Distress Syndrome. Coming to an End? ( 28035848 )
2017
10
On the complexity of scoring acute respiratory distress syndrome: do not forget hemodynamics! ( 27618840 )
2016
11
Diagnostic delay of pulmonary tuberculosis in patients with acute respiratory distress syndrome associated with aspiration pneumonia: Two case reports and a mini-review from Japan. ( 27446284 )
2016
12
Resolution acute respiratory distress syndrome through reversing the imbalance of Treg/Th17 by targeting the cAMP signaling pathway. ( 27176453 )
2016
13
Effect of Noninvasive Ventilation Delivered by Helmet vs Face Mask on the Rate of Endotracheal Intubation in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial. ( 27179847 )
2016
14
Noninvasive ventilation on mortality of acute respiratory distress syndrome. ( 27630415 )
2016
15
Efficacy of prone position in acute respiratory distress syndrome patients: A pathophysiology-based review. ( 27152255 )
2016
16
Adult onset Still's disease accompanied by acute respiratory distress syndrome: A case report. ( 27588099 )
2016
17
Ozone and Acute Respiratory Distress Syndrome. It's in the Air We Breathe. ( 27174476 )
2016
18
Severe acute respiratory distress syndrome secondary to Plasmodium vivax malaria. ( 26968294 )
2016
19
Association between functional polymorphisms in the nitric oxide synthase 3 gene and pediatric acute respiratory distress syndrome. ( 27706723 )
2016
20
Mild hypothermia attenuate kidney injury in canines with oleic acid-induced acute respiratory distress syndrome. ( 27180146 )
2016
21
Association of polymorphisms in genes of factors involved in regulation of splicing of cystic fibrosis transmembrane conductance regulator mRNA with acute respiratory distress syndrome in children with pneumonia. ( 27596159 )
2016
22
Effect of Antiplatelet Therapy on Acute Respiratory Distress Syndrome and Mortality in Critically Ill Patients: A Meta-Analysis. ( 27182704 )
2016
23
Effects of neuromuscular blockers on transpulmonary pressures in moderate to severe acute respiratory distress syndrome. ( 28013329 )
2016
24
Plasma cytokines IL-6, IL-8, and IL-10 are associated with the development of acute respiratory distress syndrome in patients with severe traumatic brain injury. ( 27630085 )
2016
25
Trials and Tribulations of Therapies for the Acute Respiratory Distress Syndrome. ( 27182881 )
2016
26
Outcomes and survival prediction models for severe adult acute respiratory distress syndrome treated with extracorporeal membrane oxygenation. ( 27919283 )
2016
27
Mass Spectrometry-based Proteomics in Acute Respiratory Distress Syndrome: A Powerful Modality for Pulmonary Precision Medicine. ( 27647196 )
2016
28
Classifying Acute Respiratory Distress Syndrome Severity: Correcting the Arterial Oxygen Partial Pressure to Fractional Inspired Oxygen at Altitude. ( 27623033 )
2016
29
Acute cor pulmonale and the acute respiratory distress syndrome. ( 26759013 )
2016
30
PaO2/FiO2 Deterioration During Stable Extracorporeal Membrane Oxygenation Associates With Protracted Recovery and Increased Mortality in Severe Acute Respiratory Distress Syndrome. ( 27592605 )
2016
31
Lugrandoside attenuates LPS-induced acute respiratory distress syndrome by anti-inflammation and anti-apoptosis in mice. ( 28078026 )
2016
32
Acute Respiratory Distress Syndrome as the Initial Clinical Manifestation of an Antisynthetase Syndrome. ( 27433180 )
2016
33
Association of rosuvastatin and delirium in severe sepsis with acute respiratory distress syndrome. ( 27618838 )
2016
34
Budesonide Attenuates Ventilator-induced Lung Injury in a Rat Model of Inflammatory Acute Respiratory Distress Syndrome. ( 27664487 )
2016
35
The Effectiveness of Corticosteroid Usage in Complex Therapy for Severe Sepsis and Acute Respiratory Distress Syndrome in Cases of Severe Traumatic Brain Injury. ( 28028977 )
2016
36
A mortality score for acute respiratory distress syndrome: predicting the future without a crystal ball. ( 27618932 )
2016
37
Authors' response to commentaries on rosuvastatin for delirium and cognitive impairment in sepsis-associated acute respiratory distress syndrome. ( 28066653 )
2016
38
Noninvasive ventilation during acute respiratory distress syndrome in patients with cancer: Trends in use and outcome. ( 28038339 )
2016
39
Effect of setting high APRV guided by expiratory inflection point of pressure-volume curve on oxygen delivery in canine models of severe acute respiratory distress syndrome. ( 27588065 )
2016
40
Pulmonary Vascular Dysfunction and Cor Pulmonale During Acute Respiratory Distress Syndrome in Sicklers. ( 27206275 )
2016
41
Acute respiratory distress syndrome caused by Mycoplasma pneumoniae without elevated pulmonary vascular permeability: a case report. ( 27162691 )
2016
42
Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Elevated in Bronchoalveolar Lavage Fluid of Patients with Acute Respiratory Distress Syndrome. ( 26919714 )
2016
43
Lung Metabolic Activation as an Early Biomarker of Acute Respiratory Distress Syndrome and Local Gene Expression Heterogeneity. ( 27611185 )
2016
44
Clinical predictors of hospital mortality differ between direct and indirect acute respiratory distress syndrome. ( 27663180 )
2016
45
Acute respiratory distress syndrome and acute myocarditis developed in a previously healthy adult with influenza B. ( 26728359 )
2016
46
Distensibility index of the inferior vena cava in experimental acute respiratory distress syndrome. ( 28017906 )
2016
47
From Berlin to Kigali: the sobering journey of acute respiratory distress syndrome. ( 27162682 )
2016
48
Mortality predictors in recipients developing acute respiratory distress syndrome due to pneumonia after kidney transplantation. ( 27185552 )
2016
49
Unmasking a Role for Noninvasive Ventilation in Early Acute Respiratory Distress Syndrome. ( 27179463 )
2016
50
Management and Outcomes of Acute Respiratory Distress Syndrome Caused by Blastomycosis: A Retrospective Case Series. ( 27149459 )
2016

Variations for Acute Respiratory Distress Syndrome

Expression for Acute Respiratory Distress Syndrome

Search GEO for disease gene expression data for Acute Respiratory Distress Syndrome.

Pathways for Acute Respiratory Distress Syndrome

Pathways related to Acute Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

(show all 32)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.78 CXCL8 IL6 LBP SFTPD TNF
2
Show member pathways
12.09 CXCL8 IL6 LBP TNF
3
Show member pathways
11.94 CXCL8 IL6 LTA TNF
4 11.9 CXCL8 IL6 TNF
5 11.85 IL6 LTA TNF
6
Show member pathways
11.84 IL6 LTA TNF
7 11.79 CXCL8 IL6 TNF
8
Show member pathways
11.79 SFTPB SFTPC SFTPD
9
Show member pathways
11.77 CXCL8 IL6 LBP
10 11.76 CXCL8 IL6 LBP TNF
11 11.75 CXCL8 IL6 TNF
12 11.72 CXCL8 IL6 LBP
13 11.66 IL6 THBD TNF
14 11.65 CXCL8 IL6 TNF
15 11.62 CXCL8 IL6 THBD TNF
16 11.61 IL6 LTA TNF
17
Show member pathways
11.55 CXCL8 IL6 TNF
18 11.54 CXCL8 LBP LTA TNF
19 11.48 CXCL8 IL6 TNF
20 11.47 LBP LTA TNF
21 11.4 CXCL8 IL6 TNF
22 11.39 CXCL8 IL6 TNF
23 11.37 ELANE IL6 TNF
24
Show member pathways
11.29 SFTPB SFTPC SFTPD
25
Show member pathways
11.24 CXCL8 IL6 LBP SFTPD TNF
26 11.16 CXCL8 IL6 THBD
27 11.08 CXCL8 IL6 LTA TNF
28 11.06 CXCL8 IL6 SFTPC TNF
29 11.03 CXCL8 TNF
30 10.99 IL6 TNF
31
Show member pathways
10.94 SFTPB SFTPC SFTPD
32 10.61 CXCL8 IL6 TNF

GO Terms for Acute Respiratory Distress Syndrome

Cellular components related to Acute Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.73 CXCL8 ELANE F5 IL6 LBP LTA
2 clathrin-coated endocytic vesicle GO:0045334 9.43 SFTPB SFTPC SFTPD
3 extracellular space GO:0005615 9.4 CXCL8 ELANE F5 IL6 LBP LTA
4 lamellar body GO:0042599 9.33 SFTPB SFTPC SFTPD
5 multivesicular body lumen GO:0097486 9.32 SFTPB SFTPC

Biological processes related to Acute Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

(show all 19)
id Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.83 ELANE LBP SFTPD TNF
2 positive regulation of smooth muscle cell proliferation GO:0048661 9.71 ELANE IL6 TNF
3 humoral immune response GO:0006959 9.69 IL6 LTA TNF
4 cellular response to lipopolysaccharide GO:0071222 9.67 CXCL8 IL6 LBP TNF
5 positive regulation of interleukin-6 production GO:0032755 9.65 IL6 LBP TNF
6 cellular protein metabolic process GO:0044267 9.65 F5 IL6 SFTPB SFTPC SFTPD
7 respiratory gaseous exchange GO:0007585 9.61 SFTPB SFTPC SFTPD
8 embryonic digestive tract development GO:0048566 9.58 CXCL8 TNF
9 negative regulation of lipid storage GO:0010888 9.58 IL6 TNF
10 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.57 ELANE TNF
11 response to yeast GO:0001878 9.56 ELANE IL6
12 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.55 IL6 TNF
13 positive regulation of chemokine production GO:0032722 9.5 IL6 LBP TNF
14 positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 9.49 LTA TNF
15 negative regulation of chemokine biosynthetic process GO:0045079 9.46 ELANE IL6
16 defense response to Gram-positive bacterium GO:0050830 9.46 IL6 LBP LTA TNF
17 positive regulation of chronic inflammatory response to antigenic stimulus GO:0002876 9.4 LTA TNF
18 response to lipopolysaccharide GO:0032496 9.35 ELANE IL6 LBP LTA THBD
19 negative regulation of growth of symbiont in host GO:0044130 8.92 ELANE LBP LTA TNF

Molecular functions related to Acute Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.92 CXCL8 IL6 LTA TNF

Sources for Acute Respiratory Distress Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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