MCID: ADD001
MIFTS: 68

Addison's Disease malady

Endocrine, Genetic categories

Summaries for Addison's Disease

Sources:
8Disease Ontology, 43NIH Rare Diseases, 34MedlinePlus, 47OMIM, 33MalaCards
See all sources

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MedlinePlus:34 Your adrenal glands are just above your kidneys. the outside layer of these glands makes hormones that help your body respond to stress and regulate your blood pressure and water and salt balance. addison disease happens if the adrenal glands don't make enough of these hormones. a problem with your immune system usually causes addison disease. the immune system mistakenly attacks your own tissues, damaging your adrenal glands. other causes include infections and cancer. symptoms include weight loss muscle weakness fatigue that gets worse over time low blood pressure patchy or dark skin lab tests can confirm that you have addison disease. if you don't treat it, it can be fatal. you will need to take hormone pills for the rest of your life. if you have addison disease, you should carry an emergency id. it should say that you have the disease, list your medicines and say how much you need in an emergency. nih: national institute of diabetes and digestive and kidney diseases

MalaCards: Addison's Disease, also known as addison disease, is related to x-linked adrenal hypoplasia congenita and hypoadrenalism. An important gene associated with Addison's Disease is CYP21A2 (cytochrome P450, family 21, subfamily A, polypeptide 2), and among its related pathways are Pregnenolone biosynthesis and Androgen biosynthesis. The drugs dexamethasone and fludrocortisone and the compounds estrogen and acth 1-24 have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, cortex and kidney, and related mouse phenotypes are endocrine/exocrine gland and behavior/neurological.

Disease Ontology:8 An adrenal cortical hypofunction that is characterized by insufficient steriod hormone production by the adrenal glands.

NIH Rare Diseases:43 Addison's disease is a condition that occurs when the adrenal glands do not produce enough of their hormones. this condition can be caused by damage to the adrenal glands, autoimmune conditions, and certain genetic conditions. some of the symptoms include changes in blood pressure, chronic diarrhea, darkening of the skin, paleness, extreme weakness, fatigue, nausea and vomiting, salt craving, and weight loss. treatment with replacement corticosteroids usually controls the symptoms. last updated: 4/28/2011

Description from OMIM:47 103230,240200

Aliases & Classifications for Addison's Disease

Sources:
8Disease Ontology, 43NIH Rare Diseases, 10DISEASES, 45Novoseek, 49Orphanet, 47OMIM, 34MedlinePlus, 61UMLS, 40NCIt, 57SNOMED-CT, 35MeSH, 36MESH via Orphanet, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic
Anatomical: Endocrine


Characteristics (Orphanet epidemiological data):

49
addison disease:
Prevalence: 1-5/10000; Age of onset: Variable; Age of death: Normal


Aliases & Descriptions:

addison's disease 8 43
addison disease 43 49 47 34 61
addisons disease 10 45
adrenocortical hypofunction, chronic primary congenital 8
addison disease, chronic adrenal insufficiency 8
addison's disease due to autoimmunity 61
primary adrenocortical insufficiency 8
adrenal cortical hypofunction 61
hypoadrenocorticism, familial 8
autoimmune addison's disease 49
hypoadrenocorticism familial 43
adrenal gland hypofunction 43
classic addison's disease 49
primary addison's disease 49
autoimmune adrenalitis 49
primary hypoadrenalism 8
adrenal hypoplasia 43
adrenal aplasia 43


External Ids:

Disease Ontology8 DOID:13774
NCIt40 C26689
MeSH35 D000224
MESH via Orphanet36 D000224
ICD10 via Orphanet26 E27.1
SNOMED-CT via Orphanet58 363732003, 76715008
UMLS via Orphanet62 C0001403, C0271737

Related Diseases for Addison's Disease

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Addison's Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 165)
idRelated DiseaseScoreTop Affiliating Genes
1x-linked adrenal hypoplasia congenita31.0NR0B1, STAR, GK
2hypoadrenalism30.7CRH, POMC
3triple-a syndrome30.4MC2R, POMC
4arthritis30.4PTPN22, POMC, CTLA4
5adrenoleukodystrophy30.3NR0B1, CYP21A2, REN, ABCD1
6hyperglycerolemia30.3NR0B1, GK, GK2
7precocious puberty30.3NR0B1, POMC, CYP21A2
8duchenne muscular dystrophy30.3GK2, GK, NR0B1
9tuberculosis30.2CYP11A1, POMC
10achalasia30.2MC2R, POMC
11hypoparathyroidism30.2CTLA4, AIRE
12vitiligo30.2CTLA4, DDC, AIRE, POMC, PTPN22
13adrenal carcinoma30.1POMC
14cushing's syndrome30.1POMC, CRH
15autoimmune polyendocrinopathy syndrome , type i, with or without reversible metaphyseal dysplasia29.9CYP11A1, CYP21A2, CYP17A1, AIRE, DDC, TPH1
16adrenal adenoma29.9CRH, POMC, CYP17A1, CYP21A2, CYP11A1, MC2R
17adenoma29.9CTLA4, CRH, NR0B1, POMC, CYP17A1, CYP21A2
18lipoid adrenal hyperplasia29.9STAR
19hypospadias29.9HSD3B2, CYP17A1, CYP21A2
20growth hormone deficiency29.9POMC, CRH
21acth deficiency29.9CRH, POMC
22adrenocortical insufficiency10.8
23adrenal cortical hypofunction10.8
24intrauterine growth restriction, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies10.5
25pituitary hypoplasia10.4
26adrenal hypoplasia, congenital, with hypogonadotropic hypogonadism10.4
27familial adrenal hypoplasia with absent pituitary luteinizing hormone10.3
28waterhouse-friderichsen syndrome10.3
29polymyalgia rheumatica10.3
30hyperprolactinemia10.2
31chronic fatigue syndrome10.2
32laugier-hunziker syndrome10.2
33autoimmune polyendocrinopathy type 210.1
34isolated x-linked adrenal hypoplasia congenita10.1
35complex glycerol kinase deficiency10.1
36congenital adrenal hypoplasia of maternal cause10.1
37pulmonary tuberculosis10.1
38adrenocortical carcinoma10.0POMC
39alopecia10.0AIRE
40candidiasis10.0AIRE
41leukemia10.0CYP27B1
42alopecia areata10.0AIRE
43diabetes insipidus10.0POMC
44klinefelter's syndrome10.0CYP21A2, NR0B1
45pseudohermaphroditism10.0HSD3B2, CYP17A1
46hypothyroidism10.0CTLA4, AIRE, POMC
47metaphyseal dysplasia10.0AIRE, NR0B1
48thyroiditis10.0PTPN22, POMC, CTLA4
49ovarian disease10.0STAR
50hepatitis10.0AIRE, DDC, CTLA4

Graphical network of the top 20 diseases related to Addison's Disease:



Diseases related to addison's disease

Clinical Features for Addison's Disease

Sources:
47OMIM
See all sources

Clinical features from OMIM:

103230,240200

Clinical synopsis from OMIM:

103230

Drugs & Therapeutics for Addison's Disease

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Addison's Disease

Drug clinical trials:

Search ClinicalTrials for Addison's Disease

Search NIH Clinical Center for Addison's Disease

Search CenterWatch for Addison's Disease

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Addison's Disease

Anatomical Context for Addison's Disease

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Addison's Disease:

33
Bone marrow, Cortex, Kidney, Thyroid, Salivary gland, Adrenal gland, Skin, Prostate, T cells, B cells, Fetal thyroid, Adrenal cortex, Pituitary

Animal Models for Addison's Disease or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

Publications for Addison's Disease

Sources:
51PubMed
See all sources

Articles related to Addison's Disease:

(show top 50)    (show all 203)
idTitleAuthorsYear
1
Addison's disease symptoms--a cross sectional study in urban South Africa. (23308244)
2013
2
Salivary cortisol day curves in assessing glucocorticoid replacement therapy in Addison's disease. (23624135)
2013
3
Addison's disease: a survey on 633 patients in Padova. (24014553)
2013
4
Thomas Addison: Addisonian (pernicious) anaemia, Addison's disease of the suprarenal gland. (23413534)
2013
5
The role of functionally defective rare germline variants of sialic acid acetylesterase in autoimmune Addison's disease. (23011869)
2012
6
Quality of life in European patients with Addison's disease: validity of the disease-specific questionnaire AddiQoL. (22090270)
2012
7
Diffuse hair loss in Addison disease: a reason for X-linked adrenoleukodystrophy screening. (22507581)
2012
8
Inadequate stress response to anaesthesia and surgery due to suspected glucocorticoid deficiency in a dog undergoing exploratory laparotomy with known Addison's disease. (22118058)
2012
9
Treatment of addison disease and subsequent hypophosphatemic respiratory failure. (22115755)
2012
10
Subclinical Addison's disease mimicking a silent corticotroph adenoma. (22156908)
2011
11
Dominant suppression of Addison's disease associated with HLA-B15. (21565792)
2011
12
Crisis averted: recognize the symptoms of Addison's disease. (21236379)
2011
13
Severe rhabdomyolysis as a first symptom in Addison's disease. (19625758)
2010
14
Screening for associated autoimmune disorders in Polish patients with Addison's disease. (20960274)
2010
15
Development of a disease-specific quality of life questionnaire in Addison's disease. (20016050)
2010
16
High-calorie glucose-rich food attenuates neuroglycopenic symptoms in patients with Addison's disease. (19965917)
2010
17
Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility. (19850680)
2009
18
The purification and application of biologically active recombinant steroid cytochrome P450 21-hydroxylase: the major autoantigen in autoimmune Addison's disease. (19329278)
2009
19
Apoptosis in subicular neurons: A comparison between suicide and Addison's disease. (20048453)
2009
20
Absence of autoantibodies connected to autoimmune polyendocrine syndrome type I and II and Addison's disease in girls and women with Turner syndrome. (18088406)
2007
21
Bilateral adrenal lymphoma with Addison's disease : a surgical pitfall. (17515276)
2007
22
Addison's disease from non-Hodgkin's lymphoma with normal-size adrenal glands. (17538179)
2007
23
A case of Addison's disease confirmed with low dose cosyntropin stimulation test. (17878604)
2007
24
Premature mortality in patients with Addison's disease: a population-based study. (16968806)
2006
25
Sex-specific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto's thyroiditis or Addison's disease in the German population. (16322396)
2005
26
Successful pregnancy outcome in a patient with primary Addison's disease. (16109594)
2005
27
Retrovirus-like long-terminal repeat DQ-LTR13 and genetic susceptibility to type 1 diabetes and autoimmune Addison's disease. (15734871)
2005
28
Moderate Dose Inhaled Budesonide Disguising Symptoms of Addison's Disease in An Asthmatic Boy with Silent Celiac Disease. (23118631)
2005
29
Unusual presentation of Addison's disease in Schmidt's syndrome. (12880129)
2003
30
Focal segmental glomerular sclerosis in two patients with Addison's disease: any more than fortuitous development of glomerular disease? (12169875)
2002
31
Survival of a 75% burn in a patient with longstanding Addison's disease. (12052380)
2002
32
A study of the epitopes on steroid 21-hydroxylase recognized by autoantibodies in patients with or without Addison's disease. (9486414)
1998
33
Mitochondrial DNA deletion with Kearns Sayre syndrome in a child with Addison disease. (9727847)
1998
34
I. Adrenal cortex and steroid 21-hydroxylase autoantibodies in adult patients with organ-specific autoimmune diseases: markers of low progression to clinical Addison's disease. (9062509)
1997
35
Similarity of symptoms in chronic fatigue syndrome and Addison's disease. (9466137)
1997
36
Clinical problem-solving: identifying Addison's disease. (8614435)
1996
37
Addison's disease. Adrenal insufficiency should be excluded before thyroxine replacement is started. (8761250)
1996
38
Clinical problem-solving: identifying Addison's disease. (8614432)
1996
39
Autopsy findings of Addison's disease caused by systemic cytomegalovirus infection in a patient with acquired immunodeficiency syndrome. (7549137)
1995
40
High diagnostic accuracy for idiopathic Addison's disease with a sensitive radiobinding assay for autoantibodies against recombinant human 21-hydroxylase. (7673419)
1995
41
Autoimmune Addison's disease--evidence for a role of steroid 21-hydroxylase autoantibodies in adrenal insufficiency. (7962352)
1994
42
Autoimmune Addison's disease. Analysis of autoantibody binding sites on human steroid 21-hydroxylase. (8405426)
1993
43
Effect of atrial natriuretic factor on basal and stimulated pituitary-adrenal function in Cushing's and Addison's disease. (8158401)
1993
44
A successful transplant of embryonic adrenal tissue in a patient with Addison's disease. (8256462)
1993
45
Steroid 21-hydroxylase is a major autoantigen involved in adult onset autoimmune Addison's disease. (1511745)
1992
46
Clinical significance of adrenal computed tomography in Addison's disease. (1294374)
1992
47
Erythrocyte insulin receptors and insulin sensitivity in adrenocortical insufficiency. Report of a case of diabetes mellitus type I with superimposed Addison's disease. (6338670)
1983
48
The structure of the juxtaglomerular apparatus in Addison's disease, Bartter's syndrome, and in Conn's syndrome: a comparative, morphometric, light microscopic study on serial secions. (818792)
1976
49
Addison's disease, status asthmaticus, and shock. (4103970)
1971
50
Dyskeratosis congenita with pigmentation, dystrophia unguium and leukoplakia oris; patient with evidence suggestive of Addison's disease. (20286479)
1947

Genetic Variations for Addison's Disease

Expression for genes affiliated with Addison's Disease

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Addison's Disease

Search GEO for disease gene expression data for Addison's Disease.

Pathways for genes affiliated with Addison's Disease

Sources:
54Reactome, 38NCBI BioSystems Database, 50PharmGKB, 30KEGG, 12EMD Millipore
See all sources

Compounds for genes affiliated with Addison's Disease

Sources:
45Novoseek, 11DrugBank, 24HMDB, 29IUPHAR, 60Tocris Bioscience, 50PharmGKB, 2BitterDB
See all sources

Compounds related to Addison's Disease according to GeneCards/GeneDecks:

(show top 50)    (show all 115)
idCompoundScoreTop Affiliating Genes
1estrogen4510.8CRHBP, TPH1
2acth 1-244510.8CYP11A1, CRH, CYP21A2, POMC, CYP17A1
3doca4510.8POMC, CYP17A1, CYP21A2, CYP11A1, REN
4Pregnenolone11 2411.8CYP11A1, CYP21A2, CYP17A1, HSD3B2
511 deoxycortisol4510.8CRH, POMC, CYP17A1, CYP21A2, REN
617-hydroxypregnenolone4510.7HSD3B2, POMC, CYP21A2, CYP17A1
7Corticotropin1110.7CRH, CYP27B1, MC2R, HSD3B2
8ketoconazole45 29 11 2413.7CYP11A1, CRH, POMC, CYP17A1, CYP27B1, CYP21A2
917-hydroxyprogesterone45 2411.7CYP11A1, REN, CYP17A1, POMC, CRH, HSD3B2
10cycloheximide4510.7STAR
113beta-hydroxysteroid4510.7CYP17A1, MC2R, CYP21A2, POMC, CYP11A1, STAR
12metyrapone60 45 1112.7CRH, POMC, CYP21A2, MC2R, TPH1
1321-deoxycortisol45 2411.7CYP17A1, POMC, CYP21A2
14aminoglutethimide45 1111.7MC2R, CYP21A2, POMC, CYP11A1
15dehydroepiandrosterone sulfate4510.7CYP11A1, CYP17A1, MC2R, CRH, HSD3B2, CYP21A2
16forskolin45 50 1112.7ABCD1, POMC, REN, CRH, STAR, CYP17A1
17corticosterone45 60 2412.7CYP11A1, CYP21A2, REN, CYP17A1, POMC, STAR
1811beta-hydroxysteroid4510.7HSD3B2, CRH, CYP17A1, CYP21A2, REN, MC2R
1917beta-hydroxysteroid4510.7HSD3B2, CYP11A1, CYP21A2, STAR, CYP17A1
20dhea4510.7CYP17A1, STAR, POMC, HSD3B2, CYP21A2, CYP11A1
21gnrh4510.7NR0B1, CRH, POMC, CYP11A1, CYP21A2, STAR
22norepinephrine45 11 2412.7DDC, POMC, GK, CYP21A2, TPH1
23catecholamine4510.7CYP21A2, POMC, DDC, CRH, REN, TPH1
24spironolactone50 45 60 29 1114.7CRH, REN, CYP21A2, POMC
25fludrocortisone45 29 1112.7POMC, CYP21A2, REN
26cortisol29 2411.7CYP21A2, HSD3B2, POMC
27androstenedione45 2411.7HSD3B2, CRH, STAR, POMC, CYP17A1, CYP21A2
28hydrocortisone45 2 60 1113.7CRHBP, POMC, CYP21A2, MC2R, REN, CRH
29acth4510.6CRHBP, CRH, HSD3B2, POMC, CYP21A2, CYP17A1
30chloramphenicol45 2 1112.6CYP21A2, DDC, CYP11A1, CRH, CYP17A1, CYP27B1
31ribonucleic acid4510.6MC2R, CYP11A1, CYP17A1, CRH, STAR, POMC
32estradiol45 11 2412.6CYP27B1, REN, CYP11A1, CYP21A2, CYP17A1, POMC
33cholesterol45 29 11 2413.6CYP11A1, HSD3B2, CTLA4, REN, STAR, NR0B1
34testosterone45 60 11 2413.6MC2R, CYP11A1, POMC, HSD3B2, CRH, STAR
35progesterone45 60 29 11 2414.6CYP21A2, STAR, HSD3B2, POMC, CYP17A1, CRHBP
36steroid4510.6HSD3B2, CTLA4, CRH, STAR, NR0B1, REN
375-hydroxytryptophan4510.6CRH, DDC, TPH1
38dexamethasone45 50 29 1113.6CYP17A1, MC2R, CYP11A1, CYP21A2, NR0B1, STAR
39cyclic amp45 2411.6CRH, NR0B1, CYP17A1, CYP27B1, CYP11A1, MC2R
40glycerol45 11 2412.6GK2, NR0B1, POMC, CRH, GK
41progestin4510.6CYP11A1, POMC, CYP17A1, STAR
42fenfluramine29 45 1112.6CRH, POMC, TPH1
43arginine4510.6POMC, PTPN22, TPH1, CYP21A2, REN, ABCD1
44homovanillic acid45 2411.5DDC, TPH1, CRH
45epinephrine45 11 2412.4CRH, DDC, POMC, CYP21A2, REN
465-hydroxyindoleacetic acid45 2411.4CRH, TPH1, DDC
47benzodiazepine4510.4GK, CRH, STAR
48cortisone45 2411.3CYP21A2, POMC, CRH
49tyrosine4510.3CTLA4, PTPN22, DDC, AIRE, CYP21A2, CYP27B1
50lipid4510.0CTLA4, STAR, CYP11A1, GK, CYP17A1, CYP21A2

GO Terms for genes affiliated with Addison's Disease

Sources:
16Gene Ontology
See all sources

Cellular components related to Addison's Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial outer membraneGO:00574110.4GK2, GK, CYP27B1
2perikaryonGO:04320410.4CRH, CRHBP, CYP11A1
3mitochondrial cristaGO:03006110.3CYP11A1, STAR
4varicosityGO:04319610.1CRH, CRHBP

Biological processes related to Addison's Disease according to GeneCards/GeneDecks:

(show all 45)
idNameGO IDScoreTop Affiliating Genes
1biphenyl metabolic processGO:01887910.8CYP11A1, STAR, CYP17A1
2dibenzo-p-dioxin metabolic processGO:01889410.8CYP17A1, STAR, CYP11A1
3response to fungicideGO:06099210.8STAR, CYP17A1, CYP11A1
4fractalkine metabolic processGO:05075610.8STAR, CYP11A1
5Leydig cell differentiationGO:03332710.8CYP11A1, CYP17A1, NR0B1
6sterol metabolic processGO:01612510.8CYP21A2, CYP17A1, CYP11A1
7phenol-containing compound metabolic processGO:01895810.8STAR, CYP17A1, CYP11A1
8phthalate metabolic processGO:01896310.8CYP11A1, CYP17A1, STAR
9glucocorticoid biosynthetic processGO:00670410.8CYP17A1, HSD3B2, CRH, CYP21A2
10cellular response to antibioticGO:07123610.8CYP11A1, CYP17A1, STAR
11steroid biosynthetic processGO:00669410.8CYP17A1, STAR, NR0B1, HSD3B2
12serotonin biosynthetic processGO:04242710.8DDC, TPH1
13adrenal gland developmentGO:03032510.8NR0B1, CYP17A1, CRH
14cellular response to cocaineGO:07131410.8CRHBP, CRH
15response to corticosterone stimulusGO:05141210.8CYP11A1, CRH, STAR
16response to insecticideGO:01708510.8CYP11A1, CYP17A1
17glycerol catabolic processGO:01956310.8GK, GK2
18xenobiotic metabolic processGO:00680510.8CYP21A2, CYP27B1, CYP17A1, CYP11A1
19steroid metabolic processGO:00820210.8STAR, CYP21A2, CYP11A1, HSD3B2, CYP17A1, CYP27B1
20mineralocorticoid biosynthetic processGO:00670510.8HSD3B2, CYP21A2
21diterpenoid metabolic processGO:01610110.8CRH, STAR
22response to immobilization stressGO:03590210.8CRH, TPH1
23cellular response to cAMPGO:07132010.8CYP11A1, STAR, CRHBP
24indolalkylamine biosynthetic processGO:04621910.8DDC, TPH1
25testosterone biosynthetic processGO:06137010.8CYP11A1, STAR
26cellular response to drugGO:03569010.7REN, DDC, CRHBP
27progesterone biosynthetic processGO:00670110.7CYP11A1, STAR
28cellular response to alkaloidGO:07131210.7DDC, STAR
29C21-steroid hormone biosynthetic processGO:00670010.7STAR, CYP11A1
30response to estrogen stimulusGO:04362710.7CRH, STAR, CYP27B1
31cellular response to follicle-stimulating hormone stimulusGO:07137210.7CYP11A1, STAR
32cellular response to lipopolysaccharideGO:07122210.7STAR, CYP17A1, CYP11A1
33cellular response to dexamethasone stimulusGO:07154910.7STAR, CRH
34response to herbicideGO:00963510.7STAR, CYP17A1
35estrogen biosynthetic processGO:00670310.6STAR, CYP11A1
36small molecule metabolic processGO:04428110.6CYP17A1, CYP27B1, CYP21A2, CYP11A1, ABCD1, TPH1
37vitamin D metabolic processGO:04235910.6CYP11A1, CYP27B1
38male gonad developmentGO:00858410.6STAR, REN, NR0B1
39androgen biosynthetic processGO:00670210.6HSD3B2, CYP17A1
40regulation of N-methyl-D-aspartate selective glutamate receptor activityGO:200031010.5CRHBP, CRH
41synaptic transmission, dopaminergicGO:00196310.5CRHBP, CRH
42glycerol metabolic processGO:00607110.4GK, GK2
43response to drugGO:04249310.4CYP11A1, CRH, CYP17A1, STAR
44hypothalamus developmentGO:02185410.3NR0B1, CRH
45cellular response to cadmium ionGO:07127610.1STAR, CYP11A1

Molecular functions related to Addison's Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1electron carrier activityGO:00905510.4CYP27B1, CYP17A1, CYP21A2, CYP11A1
2iron ion bindingGO:00550610.4TPH1, CYP11A1, CYP21A2, CYP27B1, CYP17A1
3heme bindingGO:02003710.3CYP17A1, CYP27B1, CYP21A2, CYP11A1
4glycerol kinase activityGO:00437010.1GK, GK2

Products for genes affiliated with Addison's Disease

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  • Proteins
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Sources for Addison's Disease

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet