MCID: ADN017
MIFTS: 41

Adenofibroma malady

Cancer diseases category
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Summaries for Adenofibroma

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Disease Ontology:8 A cell type benign neoplasm that is composed of glandular and fibrous tissues, with a relatively large proportion of glands.

MalaCards based summary: Adenofibroma, also known as adenofibroma, no icd-o subtype, is related to adenosarcoma and wilms tumor. An important gene associated with Adenofibroma is SHFM1 (split hand/foot malformation (ectrodactyly) type 1), and among its related pathways are Peptide hormone metabolism and Ovarian Infertility Genes. The compounds 3beta-hydroxysteroid and crcs have been mentioned in the context of this disorder. Affiliated tissues include ovary, cervix and uterus, and related mouse phenotypes are immune system and normal.

Aliases & Classifications for Adenofibroma

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 34MeSH, 57SNOMED-CT, 39NCIt
See all sources

Adenofibroma, Aliases & Descriptions:

Name: Adenofibroma 8 10 44 62
 
Adenofibroma, No Icd-O Subtype 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:2683
MeSH34 D000232
SNOMED-CT57 189823009, 2962009
NCIt39 C8984

Related Diseases for Adenofibroma

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Diseases in the Adenofibroma family:

Malignant Adenofibroma

Diseases related to Adenofibroma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 80)
idRelated DiseaseScoreTop Affiliating Genes
1adenosarcoma30.4MME, PGR
2wilms tumor30.4CALB2, MME, INHA
3cystadenoma30.3INHA, MME
4endometrial stromal sarcoma29.8INHA, PGR, MME
5endometriosis29.7PTEN, PGR, MUC16, CALB2, ARID1A
6adenocarcinoma29.5CALB2, MME, MUC16, PGR, PTEN, INHA
7endometrial carcinoma29.4MME, MUC16, PGR, PTEN
8breast cancer29.3INHA, PTEN, PGR, MUC16, MME
9papillary adenofibroma10.5
10clear cell adenofibroma10.5
11malignant peritoneal mesothelioma10.4CALB2
12cystadenocarcinoma10.4MUC16
13ovarian serous cystadenocarcinoma10.4MUC16
14proteus syndrome10.4PTEN
15nephrogenic adenofibroma10.4
16cystadenofibroma10.3
17sex cord-gonadal stromal tumor10.3CALB2, INHA
18uterine corpus adenofibroma10.3
19malignant adenofibroma10.3
20ovarian clear cell adenofibroma10.3
21granular cell tumor10.3CALB2, INHA
22endodermal sinus tumor10.3INHA, MUC16
23epithelioid sarcoma10.3MUC16, CALB2
24mucinous adenofibroma10.3
25cervical adenofibroma10.3
26clear cell adenocarcinoma10.3
27ovarian endometrioid adenofibroma10.3
28ovarian mucinous adenofibroma10.3
29leydig cell tumor10.2CALB2, INHA
30fibroma10.2CALB2, MUC16
31adrenocortical carcinoma10.2INHA, CALB2
32malignant pleural mesothelioma10.2CALB2, MUC16
33pulmonary tuberculosis10.2MUC16, INHA
34adrenal cortical adenoma10.2CALB2, INHA
35peutz-jeghers syndrome10.2PTEN, INHA
36ovarian clear cell malignant adenofibroma10.2
37ovarian mucinous malignant adenofibroma10.2
38ovarian endometrioid malignant adenofibroma10.2
39fallopian tube adenofibroma10.2
40ovarian serous adenofibroma10.2
41neurilemmoma10.2CALB2, INHA
42abrikosov's tumor10.1CALB2, MUC16, INHA
43giant adenofibroma of the breast10.1
44gynecomastia10.1INHA, PGR
45malignant mesothelioma10.1CALB2, MUC16
46seminoma10.1CALB2, INHA
47malignant mixed mullerian tumor10.1PGR, MME
48phyllode tumor10.1MME, PGR
49congestive heart failure10.0MME, MUC16
50tubular adenocarcinoma10.0MME, PGR

Graphical network of the top 20 diseases related to Adenofibroma:



Diseases related to adenofibroma

Symptoms for Adenofibroma

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Drugs & Therapeutics for Adenofibroma

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Drug clinical trials:

Search ClinicalTrials for Adenofibroma

Search NIH Clinical Center for Adenofibroma

Genetic Tests for Adenofibroma

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Anatomical Context for Adenofibroma

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MalaCards organs/tissues related to Adenofibroma:

32
Ovary, Cervix, Uterus, Lung, Testis, Liver, Breast, Kidney, Thyroid

Animal Models for Adenofibroma or affiliated genes

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MGI Mouse Phenotypes related to Adenofibroma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.2MAF, MME, PGR, PTEN, INHA
2MP:00028737.6ARID1A, CALB2, PGR, PTEN, INHA
3MP:00053767.4INHA, PTEN, PGR, MME, MAF, ARID1A

Publications for Adenofibroma

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Articles related to Adenofibroma:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
Serous surface papillary adenofibroma of the ovary: impersonator of ovarian malignancy. (24484475)
2014
2
Pulmonary adenofibroma: clinicopathological study of 3 cases of a rare benign lung lesion and review of the literature. (24908371)
2014
3
Adenofibroma in a young patient: a rare entity in an uncommon age. (24459594)
2013
4
Clear Cell Adenocarcinoma Arising from Clear Cell Adenofibroma of the Ovary: Value of DWI and DCE-MRI. (24172789)
2013
5
Metanephric adenofibroma. (23587517)
2013
6
Ovarian benign clear cell adenofibroma in a patient with premature ovarian failure after 8-year hormone replacement therapy. (23153077)
2013
7
Adenofibroma of the uterine cervix coexistent with endometriosis. (22795111)
2012
8
Unusual presentation of rare case of papillary adenofibroma of cervix in a young woman. (22606457)
2012
9
Pathogenesis of ovarian clear cell adenofibroma, atypical proliferative (borderline) tumor, and carcinoma: clinicopathologic features of tumors with endometriosis or adenofibromatous components support two related pathways of tumor development. (21479128)
2011
10
Clear cell adenocarcinoma arising in endometrial adenofibroma. (21355961)
2011
11
Serous adenofibroma of the testicle: case report and review of the literature. (20040787)
2010
12
Borderline clear cell adenofibroma with extensive hemorrhagic necrosis. (20890073)
2010
13
Mullerian adenosarcoma: a clinicopathologic and immunohistochemical study of 55 cases challenging the existence of adenofibroma. (18941402)
2009
14
Adenofibroma of the testis. (19474357)
2009
15
An allelotype analysis indicating the presence of two distinct ovarian clear-cell carcinogenic pathways: endometriosis-associated pathway vs. clear-cell adenofibroma-associated pathway. (19655165)
2009
16
Adenofibroma of the fimbria: a common entity that is indistinguishable from ovarian adenofibroma. (18580316)
2008
17
Benign clear cell adenofibroma of the ovary. A case report with literature review. (17202822)
2007
18
Endometrial adenofibroma: a rare entity. (16858575)
2007
19
Uterine adenofibroma and endometrial stromal sarcoma associated with tamoxifen therapy: MR findings. (16890405)
2006
20
Fine-needle aspiration cytology of endometrioid adenofibroma of the ovary. (15236263)
2004
21
Adenofibroma of the testis discovered at exploration for torsion after trauma. (14532817)
2003
22
Paratesticular adenofibroma. (12745730)
2003
23
Uterine cervical adenofibroma associated with Turner's syndrome in a young woman. (12410376)
2002
24
Nephrogenic adenofibroma in a young child. (11156329)
2000
25
Metanephric adenofibroma: report of a case and review of the literature. (10366157)
1999
26
Papillary adenofibroma of the uterine cervix. A case report. (8927449)
1996
27
An unusual endometrioid adenofibroma of the uterine cervix: a histologic and immunohistochemical study. (11578483)
1995
28
Significant increases in serum CA125 and CA19-9 following torsion from an adenofibroma of the ovary: a case report. (8158859)
1994
29
Biliary adenofibroma. A heretofore unrecognized benign biliary tumor of the liver. (8422113)
1993
30
Pulmonary adenofibroma: report of two cases of an unusual type of hamartomatous lesion of the lung. (8314238)
1993
31
Uterine adenofibroma mimicking endometrial carcinoma: MR findings. (1727352)
1992
32
Nephrogenic adenofibroma. A novel kidney tumor of young people. (1373578)
1992
33
Adenofibroma of the uterus: multiple recurrences following wide local excision. (2351327)
1990
34
MA1llerian adenofibroma of the uterus with invasion of myometrium and pelvic veins. (2246094)
1990
35
Ovarian clear cell adenofibroma of borderline malignancy. A case report. (2793520)
1989
36
Invasive ovarian endometrioid adenofibroma with omental implants and collision with endometrial adenocarcinoma. (3347431)
1988
37
Adenofibroma of the rete testis. A case report with electron microscopy findings. (3364196)
1988
38
Malignant endometrioid adenofibroma of the ovary with serous cystadenoma. (3728014)
1986
39
MA1llerian adenofibroma. Case report. (6518157)
1984
40
Bilateral papillary adenofibroma of the fallopian tube. (7468528)
1981
41
Adenofibroma and adenosarcoma of the uterus: a clinicopathologic study of 35 cases. (6263458)
1981
42
Cystadenofibroma, adenofibroma, and malignant adenofibroma of the ovary. (917592)
1977
43
Papillary adenofibroma of the uterus: a benign mesodermal mixed tumor of MA1llerian orgin. (4364374)
1973
44
Papillary adenofibroma of the uterine cervix. (5558981)
1971
45
Adenofibroma of urinary bladder: a case report. (13131417)
1953
46
Adenofibroma of ovary with partial differentiation to endometriosis. (18125052)
1949
47
Effect of dibenzanthracene on transplantable mammary adenofibroma of the white rat. (19970548)
1941
48
The effect of the sex hormones on the growth of transplanted mammary adenofibroma in rats. (12279175)
1940
49
Tumour of the Ovary.A ? Adenofibroma or Endothelioma. (20898235)
1909
50
Tumour of the Ovary. ? Adenofibroma or Endothelioma. (19973838)
1909

Variations for Adenofibroma

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Expression for genes affiliated with Adenofibroma

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Expression patterns in normal tissues for genes affiliated with Adenofibroma

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Pathways for genes affiliated with Adenofibroma

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Pathways related to Adenofibroma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7MME, INHA
29.6PGR, INHA

Compounds for genes affiliated with Adenofibroma

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Compounds related to Adenofibroma according to GeneCards/GeneDecks:

(show all 25)
idCompoundScoreTop Affiliating Genes
13beta-hydroxysteroid449.6PGR, INHA
2crcs449.6MME, PTEN
3taxane449.6PGR, PTEN
4gnrh449.5INHA, PGR, MME
5diethylstilbestrol44 28 1111.4PGR, PTEN
6ribonucleic acid449.4MME, PGR, INHA
7b 723449.3MUC16, CALB2
8trastuzumab44 50 1111.2PGR, PTEN
9cyclophosphamide44 50 1111.1MUC16, PGR, PTEN
10fatty acid449.1INHA, PTEN, MME
11cycloheximide448.9MME, PGR, PTEN
12hyaluronic acid44 249.8PTEN, MUC16, CALB2
13leucine448.8MAF, MME, PTEN
14estradiol44 24 1110.7MUC16, PGR, PTEN, INHA
15glucose448.7PTEN, MUC16, MME, MAF
16doxorubicin44 50 1110.7PTEN, PGR, MUC16, MME
17vegf448.7MME, MUC16, PGR, PTEN
18hematoxylin448.5INHA, PTEN, MUC16, CALB2
19paclitaxel44 50 1110.3PTEN, PGR, MUC16, CALB2
20tyrosine448.0INHA, PTEN, MUC16, MME, CALB2
21paraffin447.6CALB2, MME, MUC16, PGR, PTEN, INHA
22progesterone44 28 61 24 1111.6INHA, PTEN, PGR, MUC16, MME, CALB2
23testosterone44 61 24 1110.6INHA, PTEN, PGR, MUC16, MME, CALB2
24steroid447.5INHA, PTEN, PGR, MUC16, MME, CALB2
25estrogen447.5INHA, PTEN, PGR, MUC16, MME, CALB2

GO Terms for genes affiliated with Adenofibroma

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Molecular functions related to Adenofibroma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.2ARID1A, MME, MUC16, PGR, PTEN, SHFM1

Products for genes affiliated with Adenofibroma

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Sources for Adenofibroma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet