Summaries for Adenofibroma

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Disease Ontology:9 A cell type benign neoplasm that is composed of glandular and fibrous tissues, with a relatively large proportion of glands.

MalaCards based summary: Adenofibroma, also known as adenofibroma, no icd-o subtype, is related to adenosarcoma and wilms tumor. An important gene associated with Adenofibroma is SHFM1 (split hand/foot malformation (ectrodactyly) type 1), and among its related pathways are Peptide hormone metabolism and Ovarian Infertility Genes. The compounds 3beta-hydroxysteroid and crcs have been mentioned in the context of this disorder. Affiliated tissues include ovary, cervix and uterus, and related mouse phenotypes are immune system and normal.

Aliases & Classifications for Adenofibroma

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 33MeSH, 55SNOMED-CT, 38NCIt
See all sources

Adenofibroma, Aliases & Descriptions:

Name: Adenofibroma 9 11 43 60
 
Adenofibroma, No Icd-O Subtype 9


External Ids:

Disease Ontology9 DOID:2683
MeSH33 D000232
SNOMED-CT55 2962009, 189823009
NCIt38 C8984

Related Diseases for Adenofibroma

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Diseases in the Adenofibroma family:

Malignant Adenofibroma

Diseases related to Adenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 82)
idRelated DiseaseScoreTop Affiliating Genes
1adenosarcoma30.4MME, PGR
2wilms tumor30.4CALB2, MME, INHA
3cystadenoma30.3INHA, MME
4endometrial stromal sarcoma29.8INHA, PGR, MME
5endometriosis29.6PTEN, PGR, MUC16, CALB2, ARID1A
6adenocarcinoma29.5CALB2, MME, MUC16, PGR, PTEN, INHA
7breast cancer29.4INHA, PTEN, PGR, MUC16, MME
8papillary adenofibroma10.5
9clear cell adenofibroma10.5
10malignant peritoneal mesothelioma10.4CALB2
11nephrogenic adenofibroma10.4
12cystadenocarcinoma10.4MUC16
13ovarian serous cystadenocarcinoma10.4MUC16
14proteus syndrome, somatic10.4PTEN
15cystadenofibroma10.3
16ovarian clear cell adenofibroma10.3
17mucinous adenofibroma10.3
18cervical adenofibroma10.3
19uterine corpus adenofibroma10.3
20fallopian tube adenofibroma10.3
21malignant adenofibroma10.3
22ovarian endometrioid adenofibroma10.3
23ovarian mucinous adenofibroma10.3
24sex cord-gonadal stromal tumor10.3CALB2, INHA
25granular cell tumor10.3CALB2, INHA
26endodermal sinus tumor10.3INHA, MUC16
27clear cell adenocarcinoma10.3
28ovarian serous adenofibroma10.3
29epithelioid sarcoma10.3MUC16, CALB2
30leydig cell tumor10.2CALB2, INHA
31fibroma10.2CALB2, MUC16
32adrenocortical carcinoma10.2INHA, CALB2
33pulmonary tuberculosis10.2MUC16, INHA
34adrenal cortical adenoma10.2CALB2, INHA
35malignant pleural mesothelioma10.2CALB2, MUC16
36peutz-jeghers syndrome10.2PTEN, INHA
37ovarian clear cell malignant adenofibroma10.2
38ovarian mucinous malignant adenofibroma10.2
39ovarian endometrioid malignant adenofibroma10.2
40giant adenofibroma of the breast10.2
41neurilemmoma10.2CALB2, INHA
42chromosomal triplication10.2MAF, CALB2
43mesothelioma, somatic10.1MUC16, CALB2
44ectopic pregnancy10.1
45abrikosov's tumor10.1CALB2, MUC16, INHA
46gynecomastia10.1INHA, PGR
47mesothelioma10.1CALB2, MUC16
48seminoma10.1CALB2, INHA
49malignant mixed mullerian tumor10.1PGR, MME
50benign breast phyllodes tumor10.0MME, PGR

Graphical network of the top 20 diseases related to Adenofibroma:



Diseases related to adenofibroma

Symptoms for Adenofibroma

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Drugs & Therapeutics for Adenofibroma

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Drug clinical trials:

Search ClinicalTrials for Adenofibroma

Search NIH Clinical Center for Adenofibroma

Genetic Tests for Adenofibroma

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Anatomical Context for Adenofibroma

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MalaCards organs/tissues related to Adenofibroma:

31
Ovary, Cervix, Uterus, Lung, Breast, Testis, Liver, Kidney, Thyroid

Animal Models for Adenofibroma or affiliated genes

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MGI Mouse Phenotypes related to Adenofibroma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.2MAF, MME, PGR, PTEN, INHA
2MP:00028737.6ARID1A, CALB2, PGR, PTEN, INHA
3MP:00053767.4INHA, PTEN, PGR, MME, MAF, ARID1A

Publications for Adenofibroma

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Articles related to Adenofibroma:

(show top 50)    (show all 100)
idTitleAuthorsYear
1
Serous surface papillary adenofibroma of the ovary: impersonator of ovarian malignancy. (24484475)
2014
2
Pulmonary adenofibroma: clinicopathological study of 3 cases of a rare benign lung lesion and review of the literature. (24908371)
2014
3
A case of fallopian tube adenofibroma: difficulties associated with differentiation from ectopic pregnancy. (25525402)
2014
4
Adenofibroma in a young patient: a rare entity in an uncommon age. (24459594)
2013
5
Clear Cell Adenocarcinoma Arising from Clear Cell Adenofibroma of the Ovary: Value of DWI and DCE-MRI. (24172789)
2013
6
Metanephric adenofibroma. (23587517)
2013
7
Ovarian benign clear cell adenofibroma in a patient with premature ovarian failure after 8-year hormone replacement therapy. (23153077)
2013
8
Adenofibroma of the uterine cervix coexistent with endometriosis. (22795111)
2012
9
Unusual presentation of rare case of papillary adenofibroma of cervix in a young woman. (22606457)
2012
10
Pathogenesis of ovarian clear cell adenofibroma, atypical proliferative (borderline) tumor, and carcinoma: clinicopathologic features of tumors with endometriosis or adenofibromatous components support two related pathways of tumor development. (21479128)
2011
11
Clear cell adenocarcinoma arising in endometrial adenofibroma. (21355961)
2011
12
Serous adenofibroma of the testicle: case report and review of the literature. (20040787)
2010
13
Borderline clear cell adenofibroma with extensive hemorrhagic necrosis. (20890073)
2010
14
Mullerian adenosarcoma: a clinicopathologic and immunohistochemical study of 55 cases challenging the existence of adenofibroma. (18941402)
2009
15
Adenofibroma of the testis. (19474357)
2009
16
An allelotype analysis indicating the presence of two distinct ovarian clear-cell carcinogenic pathways: endometriosis-associated pathway vs. clear-cell adenofibroma-associated pathway. (19655165)
2009
17
Adenofibroma of the fimbria: a common entity that is indistinguishable from ovarian adenofibroma. (18580316)
2008
18
Benign clear cell adenofibroma of the ovary. A case report with literature review. (17202822)
2007
19
Endometrial adenofibroma: a rare entity. (16858575)
2007
20
Uterine adenofibroma and endometrial stromal sarcoma associated with tamoxifen therapy: MR findings. (16890405)
2006
21
Fine-needle aspiration cytology of endometrioid adenofibroma of the ovary. (15236263)
2004
22
Adenofibroma of the testis discovered at exploration for torsion after trauma. (14532817)
2003
23
Paratesticular adenofibroma. (12745730)
2003
24
Uterine cervical adenofibroma associated with Turner's syndrome in a young woman. (12410376)
2002
25
Nephrogenic adenofibroma in a young child. (11156329)
2000
26
Metanephric adenofibroma: report of a case and review of the literature. (10366157)
1999
27
Sonographic characteristics of adenofibroma of the endometrium following tamoxifen therapy for breast cancer: two case reports. (8774105)
1996
28
Papillary adenofibroma of the uterine cervix. A case report. (8927449)
1996
29
Significant increases in serum CA125 and CA19-9 following torsion from an adenofibroma of the ovary: a case report. (8158859)
1994
30
Biliary adenofibroma. A heretofore unrecognized benign biliary tumor of the liver. (8422113)
1993
31
Pulmonary adenofibroma: report of two cases of an unusual type of hamartomatous lesion of the lung. (8314238)
1993
32
Uterine adenofibroma mimicking endometrial carcinoma: MR findings. (1727352)
1992
33
Nephrogenic adenofibroma. A novel kidney tumor of young people. (1373578)
1992
34
Adenofibroma of the uterus: multiple recurrences following wide local excision. (2351327)
1990
35
Ovarian clear cell adenofibroma of borderline malignancy. A case report. (2793520)
1989
36
Invasive ovarian endometrioid adenofibroma with omental implants and collision with endometrial adenocarcinoma. (3347431)
1988
37
Adenofibroma of the rete testis. A case report with electron microscopy findings. (3364196)
1988
38
Malignant endometrioid adenofibroma of the ovary with serous cystadenoma. (3728014)
1986
39
MA1llerian adenofibroma. Case report. (6518157)
1984
40
Bilateral papillary adenofibroma of the fallopian tube. (7468528)
1981
41
Adenofibroma and adenosarcoma of the uterus: a clinicopathologic study of 35 cases. (6263458)
1981
42
Cystadenofibroma, adenofibroma, and malignant adenofibroma of the ovary. (917592)
1977
43
Papillary adenofibroma of the uterus: a benign mesodermal mixed tumor of MA1llerian orgin. (4364374)
1973
44
Papillary adenofibroma of the uterine cervix. (5558981)
1971
45
Adenofibroma of urinary bladder: a case report. (13131417)
1953
46
Adenofibroma of ovary with partial differentiation to endometriosis. (18125052)
1949
47
Effect of dibenzanthracene on transplantable mammary adenofibroma of the white rat. (19970548)
1941
48
The effect of the sex hormones on the growth of transplanted mammary adenofibroma in rats. (12279175)
1940
49
Tumour of the Ovary.A ? Adenofibroma or Endothelioma. (20898235)
1909
50
Tumour of the Ovary. ? Adenofibroma or Endothelioma. (19973838)
1909

Variations for Adenofibroma

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Expression for genes affiliated with Adenofibroma

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Search GEO for disease gene expression data for Adenofibroma.

Pathways for genes affiliated with Adenofibroma

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Pathways related to Adenofibroma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7MME, INHA
29.6PGR, INHA

Compounds for genes affiliated with Adenofibroma

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Compounds related to Adenofibroma according to GeneCards Suite gene sharing:

(show all 25)
idCompoundScoreTop Affiliating Genes
13beta-hydroxysteroid439.6PGR, INHA
2crcs439.6MME, PTEN
3taxane439.6PGR, PTEN
4gnrh439.5INHA, PGR, MME
5diethylstilbestrol43 28 1211.4PGR, PTEN
6ribonucleic acid439.4MME, PGR, INHA
7b 723439.3MUC16, CALB2
8trastuzumab43 49 1211.2PGR, PTEN
9cyclophosphamide43 49 1211.1MUC16, PGR, PTEN
10fatty acid439.1INHA, PTEN, MME
11cycloheximide438.9MME, PGR, PTEN
12hyaluronic acid43 249.8PTEN, MUC16, CALB2
13leucine438.8MAF, MME, PTEN
14estradiol43 24 1210.7MUC16, PGR, PTEN, INHA
15glucose438.7PTEN, MUC16, MME, MAF
16doxorubicin43 49 1210.7PTEN, PGR, MUC16, MME
17vegf438.7MME, MUC16, PGR, PTEN
18hematoxylin438.5INHA, PTEN, MUC16, CALB2
19paclitaxel43 49 1210.3PTEN, PGR, MUC16, CALB2
20tyrosine438.0INHA, PTEN, MUC16, MME, CALB2
21paraffin437.6CALB2, MME, MUC16, PGR, PTEN, INHA
22progesterone43 28 59 24 1211.6INHA, PTEN, PGR, MUC16, MME, CALB2
23testosterone43 59 24 1210.6INHA, PTEN, PGR, MUC16, MME, CALB2
24steroid437.5INHA, PTEN, PGR, MUC16, MME, CALB2
25estrogen437.5INHA, PTEN, PGR, MUC16, MME, CALB2

GO Terms for genes affiliated with Adenofibroma

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Molecular functions related to Adenofibroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00055157.2ARID1A, MME, MUC16, PGR, PTEN, SHFM1

Products for genes affiliated with Adenofibroma

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Sources for Adenofibroma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet