MCID: ADN064
MIFTS: 28

Adenohypophysitis malady

Categories: Endocrine diseases, Rare diseases

Aliases & Classifications for Adenohypophysitis

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Sources:
31ICD10 via Orphanet, 54Orphanet
See all MalaCards sources

Aliases & Descriptions for Adenohypophysitis:

Name: Adenohypophysitis 54
 
Anterior Pituitary Hypophysitis 54

Classifications:



External Ids:

Orphanet54 ORPHA95512
ICD10 via Orphanet31 E23.6

Summaries for Adenohypophysitis

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MalaCards based summary: Adenohypophysitis, also known as anterior pituitary hypophysitis, is related to gershoni-baruch syndrome and 7q11.23 duplication syndrome. An important gene associated with Adenohypophysitis is PRL (Prolactin), and among its related pathways are Growth hormone receptor signaling and Glucocorticoid receptor regulatory network. Affiliated tissues include pituitary, thyroid and placenta, and related mouse phenotype endocrine/exocrine gland.

Related Diseases for Adenohypophysitis

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Diseases related to Adenohypophysitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 86)
idRelated DiseaseScoreTop Affiliating Genes
1gershoni-baruch syndrome10.2PRL, TRH
27q11.23 duplication syndrome10.2GH1, PRL
3grin2a-related speech disorders and epilepsy10.2GH1, PRL
4cerebral hemisphere lipoma10.2GH1, PRL
5glaucoma, hereditary adult type 1a10.2GH1, PRL
6osseous heteroplasia, progressive10.1GH1, PRL
7plasmalogens synthesis deficiency isolated10.1GH1, PRL
8african histoplasmosis10.1POMC, PRL
9vertebral artery occlusion10.1POMC, PRL
10extragonadal nonseminomatous germ cell tumor10.1POMC, PRL
11wheat allergy10.1POMC, PRL
12pancreatic colloid cystadenoma10.1POMC, PRL
13nonparalytic poliomyelitis10.1POMC, PRL
14dacryoadenitis10.1POMC, PRL
15endometrial mixed adenocarcinoma10.1POMC, TRH
16kindler syndrome10.1POMC, PRL
17bone benign neoplasm10.1POMC, PRL
18axial osteomalacia10.1GH1, PRL
19papillary craniopharyngioma10.1PRL, TRH
20acute laryngitis10.1POMC, PRL
21sphingolipidosis10.1POMC, PRL
22chronic duodenal ileus10.1CD4, POMC
23macrocephaly, benign familial10.1GH1, POMC
24merkel cell carcinoma10.1POMC, PRL
25esophagus squamous cell papilloma10.1POMC, PRL
26astroblastoma10.1POMC, PRL
27villonodular synovitis10.1CD4, POMC
28capillary disease10.1POMC, PRL
29hypogonadism cardiomyopathy10.1GH1, POMC
30transmitted_by10.1POMC, PRL
31elephantiasis10.1CD4, POMC
32adenoma10.1
33pelvic muscle wasting10.0POMC, PRL
34fatty liver disease10.0POMC, PRL
35immune-mediated encephalomyelitis10.0IL2RA, PRL
36pituitary adenoma10.0
37spondylolysis10.0POMC, PRL
38glomangiomyoma10.0GH1, PRL, TRH
39lens-induced iridocyclitis10.0CD4, IL2RA
40ciliary discoordination, due to random ciliary orientation10.0CD4, IL2RA
41immune system organ benign neoplasm10.0POMC, PRL, TRH
42adrenal cortical adenocarcinoma10.0POMC, PRL, TRH
43acute gonococcal salpingitis10.0POMC, PRL, TRH
44avoidant personality disorder10.0POMC, PRL
45aflatoxins-related hepatocellular carcinoma10.0POMC, PRL, TRH
46endocrine organ benign neoplasm10.0POMC, PRL, TRH
47vestibular gland benign neoplasm10.0POMC, PRL, TRH
48squamous cell papilloma of skin9.9CD4, IL2RA
49intermittent squint9.9GH1, POMC, PRL
50caudal regression syndrome9.9GH1, POMC, PRL

Graphical network of the top 20 diseases related to Adenohypophysitis:



Diseases related to adenohypophysitis

Symptoms & Phenotypes for Adenohypophysitis

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MGI Mouse Phenotypes related to Adenohypophysitis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053797.6CD4, IL2RA, POMC, PRL, TRH

Drugs & Therapeutics for Adenohypophysitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Adenohypophysitis

Genetic Tests for Adenohypophysitis

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Anatomical Context for Adenohypophysitis

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MalaCards organs/tissues related to Adenohypophysitis:

36
Pituitary, Thyroid, Placenta

Publications for Adenohypophysitis

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Articles related to Adenohypophysitis:

(show top 50)    (show all 65)
idTitleAuthorsYear
1
Post-partum hypoglycemia and hypothermia as first manifestations of lymphocytic adenohypophysitis: A case report. (26786534)
2016
2
Congenital adenohypophyseal hypoplasia associated with secondary hypothyroidism in a 2-week-old Portuguese water dog. (23204587)
2012
3
Lymphocytic adenohypophysitis. (21592417)
2011
4
Lymphocytic adenohypophysitis and adrenalitis in a dog with adrenal and thyroid atrophy. (20807820)
2010
5
Adenohypophysitis in rat pituitary allografts. (20586813)
2010
6
Relationship of plasma ghrelin and adenohypophyseal hormone levels in female precocious puberty]. (18925720)
2008
7
Adrenomedullin expression in pituitary adenomas and nontumoral adenohypophyses. (17952853)
2008
8
Clusterin expression in non-neoplastic adenohypophyses and pituitary adenomas: cytoplasmic clusterin localization in adenohypophysis is related to aging. (18239862)
2008
9
Granulomatous adenohypophysitis after interferon and ribavirin therapy. (17490932)
2007
10
Longitudinal study of patients with idiopathic isolated TSH deficiency: possible progression of pituitary dysfunction in lymphocytic adenohypophysitis. (16896268)
2006
11
Pituitary apoplexy as a consequence of lymphocytic adenohypophysitis in a pregnant woman: a case report. (15949237)
2005
12
Expression of adenohypophyseal-hormone receptors in a murine folliculo-stellate cell line. (15326563)
2004
13
Therapy for lymphocytic adenohypophysitis. (12636229)
2003
14
Lymphocytic adenohypophysitis simulating a pituitary adenoma in a pregnant woman. (12528294)
2002
15
Thyrotropin-releasing hormone-induced down-regulation of pyroglutamyl aminopeptidase II activity involves L-type calcium channels and cam kinase activities in cultures of adenohypophyseal cells. (11999717)
2002
16
Severe lymphocytic adenohypophysitis with selective disappearance of prolactin cells: a histologic, ultrastructural and immunoelectron microscopic study. (11515793)
2001
17
Lymphocytic adenohypophysitis mimicking a pituitary macroadenoma. (10926106)
2000
18
The regulation of adenohypophyseal prolactin secretion: effect of triiodothyronine and methylene blue on estrogenized rat adenohypophysis. (10984069)
2000
19
Spontaneous recovery from pathologically confirmed lymphocytic adenohypophysitis with a dramatic reduction of hypophyseal size. (10563747)
1999
20
Comparative immunohistochemical study of stellate cells in normal canine and equine adenohypophyses and in pituitary tumours. (9500236)
1998
21
Lymphocytic adenohypophysitis: skull radiographs and MRI. (9541922)
1998
22
Multiple hypothalamic factors regulate pyroglutamyl peptidase II in cultures of adenohypophyseal cells: role of the cAMP pathway. (9576608)
1998
23
Lymphocytic adenohypophysitis and neurohypophysitis. (9187559)
1997
24
Lymphocytic adenohypophysitis and lymphocytic infundibuloneurohypophysitis. (9152609)
1997
25
Long-term clinical course of two cases of lymphocytic adenohypophysitis. (8930533)
1996
26
Effects of intravenously infused pituitary adenylate cyclase-activating polypeptide on adenohypophyseal Hormone secretion in normal men. (8875442)
1996
27
Differentiating lymphocytic adenohypophysitis from pituitary adenoma in the peripartum patient. (7623353)
1995
28
Lymphocytic adenohypophysitis: magnetic resonance imaging features of two new cases and a review of the literature. (7758238)
1995
29
Lymphocytic adenohypophysitis: contrast-enhanced MR imaging in five cases. (7892490)
1995
30
Immunohistochemical demonstration of adenohypophyseal hormones during postnatal ontogenesis in the Gray Short-tailed Opossum, Monodelphis domestica (marsupialia). (8835137)
1995
31
Lymphocytic Adenohypophysitis Associated with Rathke's Cleft Cyst. (12114815)
1995
32
Thyrotropin-releasing hormone downregulates pyroglutamyl peptidase II activity in adenohypophyseal cells. (7969791)
1994
33
Membrane receptors and coupling proteins in adenohypophyseal cells]. (8242419)
1993
34
Adenohypophyseal and sex hormones in pediatric rheumatic diseases. (8496873)
1993
35
Preoperative diagnosis of lymphocytic hypophysitis (adenohypophysitis) unresponsive to short course dexamethasone: case report. (1545900)
1992
36
Lymphocytic adenohypophysitis with sudden onset of diabetes insipidus in menopausal female--case report. (1381061)
1992
37
Lymphocytic adenohypophysitis: a pituitary mass lesion occurring in pregnancy. Proposal for medical treatment. (2048602)
1991
38
Adenohypophysitis associated with sebaceous gland atrophy in a dog. (1949513)
1991
39
Lymphocytic adenohypophysitis presenting as infertility. Case report. (2013781)
1991
40
Lymphocytic adenohypophysitis: an immunohistochemical study. (1891758)
1991
41
A case of pregnancy-induced lymphocytic adenohypophysitis complicated by postpartum painless thyroiditis]. (2070891)
1991
42
Lymphocytic adenohypophysitis accompanying occlusion of bilateral internal carotid arteries--case report. (1699152)
1990
43
Relationship between adenohypophyseal and steroid hormones and variations in serum and urinary melatonin levels during the ovarian cycle, perimenopause and menopause in healthy women. (2308340)
1990
44
Twenty-four-hour rhythms in plasma concentrations of adenohypophyseal hormones are generated by distinct amplitude and/or frequency modulation of underlying pituitary secretory bursts. (2172282)
1990
45
The effect of oxytocin infusion on adenohypophyseal function in man. (2160873)
1990
46
Lymphocytic adenohypophysitis: report of two cases. (2700055)
1989
47
Lymphocytic adenohypophysitis. Report of a case with demonstration of spontaneous tumour regression and a review of the literature. (3077051)
1988
48
Lymphocytic adenohypophysitis: clinical, radiological, and magnetic resonance imaging characterization. (3380286)
1988
49
A case of hypopituitarism due to granulomatous and lymphocytic adenohypophysitis with minimal pituitary enlargement: a possible variant of lymphocytic adenohypophysitis. (3215147)
1988
50
Lymphocytic adenohypophysitis. (3278777)
1988

Variations for Adenohypophysitis

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Expression for genes affiliated with Adenohypophysitis

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Search GEO for disease gene expression data for Adenohypophysitis.

Pathways for genes affiliated with Adenohypophysitis

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GO Terms for genes affiliated with Adenohypophysitis

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Cellular components related to Adenohypophysitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endosome lumenGO:003190410.1GH1, PRL
2secretory granuleGO:00301419.0POMC, PRL, TRH

Biological processes related to Adenohypophysitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1JAK-STAT cascade involved in growth hormone signaling pathwayGO:006039710.2GH1, PRL
2positive regulation of JAK-STAT cascadeGO:004642710.1GH1, PRL
3positive regulation of peptidyl-tyrosine phosphorylationGO:005073110.0CD4, GH1
4positive regulation of T cell proliferationGO:00421029.7CD4, IL2RA
5cell surface receptor signaling pathwayGO:00071669.3CD4, IL2RA, PRL
6response to estradiolGO:00323559.0CD4, GH1, PRL

Molecular functions related to Adenohypophysitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1prolactin receptor bindingGO:00051489.5GH1, PRL
2hormone activityGO:00051798.4GH1, POMC, PRL, TRH

Sources for Adenohypophysitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet