MCID: ADN064
MIFTS: 28

Adenohypophysitis malady

Categories: Endocrine diseases, Rare diseases

Aliases & Classifications for Adenohypophysitis

Aliases & Descriptions for Adenohypophysitis:

Name: Adenohypophysitis 56
Anterior Pituitary Hypophysitis 56

Classifications:

Orphanet: 56  
Rare endocrine diseases


External Ids:

Orphanet 56 ORPHA95512
ICD10 via Orphanet 34 E23.6

Summaries for Adenohypophysitis

MalaCards based summary : Adenohypophysitis, also known as anterior pituitary hypophysitis, is related to gershoni-baruch syndrome and 7q11.23 duplication syndrome. An important gene associated with Adenohypophysitis is PRL (Prolactin), and among its related pathways/superpathways are Cytokine Signaling in Immune system and PI3K-Akt signaling pathway. Affiliated tissues include pituitary, thyroid and placenta, and related phenotype is endocrine/exocrine gland.

Related Diseases for Adenohypophysitis

Diseases related to Adenohypophysitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
id Related Disease Score Top Affiliating Genes
1 gershoni-baruch syndrome 10.2 PRL TRH
2 7q11.23 duplication syndrome 10.2 GH1 PRL
3 grin2a-related speech disorders and epilepsy 10.2 GH1 PRL
4 cerebral hemisphere lipoma 10.2 GH1 PRL
5 glaucoma, hereditary adult type 1a 10.2 GH1 PRL
6 osseous heteroplasia, progressive 10.1 GH1 PRL
7 plasmalogens synthesis deficiency isolated 10.1 GH1 PRL
8 african histoplasmosis 10.1 POMC PRL
9 vertebral artery occlusion 10.1 POMC PRL
10 extragonadal nonseminomatous germ cell tumor 10.1 POMC PRL
11 wheat allergy 10.1 POMC PRL
12 pancreatic colloid cystadenoma 10.1 POMC PRL
13 nonparalytic poliomyelitis 10.1 POMC PRL
14 dacryoadenitis 10.1 POMC PRL
15 endometrial mixed adenocarcinoma 10.1 POMC TRH
16 kindler syndrome 10.1 POMC PRL
17 bone benign neoplasm 10.1 POMC PRL
18 axial osteomalacia 10.1 GH1 PRL
19 papillary craniopharyngioma 10.1 PRL TRH
20 acute laryngitis 10.1 POMC PRL
21 sphingolipidosis 10.1 POMC PRL
22 chronic duodenal ileus 10.1 CD4 POMC
23 macrocephaly, benign familial 10.1 GH1 POMC
24 merkel cell carcinoma 10.1 POMC PRL
25 esophagus squamous cell papilloma 10.1 POMC PRL
26 astroblastoma 10.1 POMC PRL
27 villonodular synovitis 10.1 CD4 POMC
28 capillary disease 10.1 POMC PRL
29 hypogonadism cardiomyopathy 10.1 GH1 POMC
30 transmitted_by 10.1 POMC PRL
31 elephantiasis 10.1 CD4 POMC
32 adenoma 10.1
33 pelvic muscle wasting 10.0 POMC PRL
34 fatty liver disease 10.0 POMC PRL
35 immune-mediated encephalomyelitis 10.0 IL2RA PRL
36 pituitary adenoma 10.0
37 spondylolysis 10.0 POMC PRL
38 glomangiomyoma 10.0 GH1 PRL TRH
39 lens-induced iridocyclitis 10.0 CD4 IL2RA
40 ciliary discoordination, due to random ciliary orientation 10.0 CD4 IL2RA
41 immune system organ benign neoplasm 10.0 POMC PRL TRH
42 adrenal cortical adenocarcinoma 10.0 POMC PRL TRH
43 acute gonococcal salpingitis 10.0 POMC PRL TRH
44 avoidant personality disorder 10.0 POMC PRL
45 aflatoxins-related hepatocellular carcinoma 10.0 POMC PRL TRH
46 endocrine organ benign neoplasm 10.0 POMC PRL TRH
47 vestibular gland benign neoplasm 10.0 POMC PRL TRH
48 squamous cell papilloma of skin 9.9 CD4 IL2RA
49 intermittent squint 9.9 GH1 POMC PRL
50 caudal regression syndrome 9.9 GH1 POMC PRL

Graphical network of the top 20 diseases related to Adenohypophysitis:



Diseases related to Adenohypophysitis

Symptoms & Phenotypes for Adenohypophysitis

MGI Mouse Phenotypes related to Adenohypophysitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.02 CD4 IL2RA POMC PRL TRH

Drugs & Therapeutics for Adenohypophysitis

Search Clinical Trials , NIH Clinical Center for Adenohypophysitis

Genetic Tests for Adenohypophysitis

Anatomical Context for Adenohypophysitis

MalaCards organs/tissues related to Adenohypophysitis:

39
Pituitary, Thyroid, Placenta

Publications for Adenohypophysitis

Articles related to Adenohypophysitis:

(show top 50) (show all 65)
id Title Authors Year
1
Post-partum hypoglycemia and hypothermia as first manifestations of lymphocytic adenohypophysitis: A case report. ( 26786534 )
2016
2
Congenital adenohypophyseal hypoplasia associated with secondary hypothyroidism in a 2-week-old Portuguese water dog. ( 23204587 )
2012
3
Lymphocytic adenohypophysitis. ( 21592417 )
2011
4
Lymphocytic adenohypophysitis and adrenalitis in a dog with adrenal and thyroid atrophy. ( 20807820 )
2010
5
Adenohypophysitis in rat pituitary allografts. ( 20586813 )
2010
6
[Relationship of plasma ghrelin and adenohypophyseal hormone levels in female precocious puberty]. ( 18925720 )
2008
7
Adrenomedullin expression in pituitary adenomas and nontumoral adenohypophyses. ( 17952853 )
2008
8
Clusterin expression in non-neoplastic adenohypophyses and pituitary adenomas: cytoplasmic clusterin localization in adenohypophysis is related to aging. ( 18239862 )
2008
9
Granulomatous adenohypophysitis after interferon and ribavirin therapy. ( 17490932 )
2007
10
Longitudinal study of patients with idiopathic isolated TSH deficiency: possible progression of pituitary dysfunction in lymphocytic adenohypophysitis. ( 16896268 )
2006
11
Pituitary apoplexy as a consequence of lymphocytic adenohypophysitis in a pregnant woman: a case report. ( 15949237 )
2005
12
Expression of adenohypophyseal-hormone receptors in a murine folliculo-stellate cell line. ( 15326563 )
2004
13
Therapy for lymphocytic adenohypophysitis. ( 12636229 )
2003
14
Lymphocytic adenohypophysitis simulating a pituitary adenoma in a pregnant woman. ( 12528294 )
2002
15
Thyrotropin-releasing hormone-induced down-regulation of pyroglutamyl aminopeptidase II activity involves L-type calcium channels and cam kinase activities in cultures of adenohypophyseal cells. ( 11999717 )
2002
16
Severe lymphocytic adenohypophysitis with selective disappearance of prolactin cells: a histologic, ultrastructural and immunoelectron microscopic study. ( 11515793 )
2001
17
Lymphocytic adenohypophysitis mimicking a pituitary macroadenoma. ( 10926106 )
2000
18
The regulation of adenohypophyseal prolactin secretion: effect of triiodothyronine and methylene blue on estrogenized rat adenohypophysis. ( 10984069 )
2000
19
Spontaneous recovery from pathologically confirmed lymphocytic adenohypophysitis with a dramatic reduction of hypophyseal size. ( 10563747 )
1999
20
Comparative immunohistochemical study of stellate cells in normal canine and equine adenohypophyses and in pituitary tumours. ( 9500236 )
1998
21
Lymphocytic adenohypophysitis: skull radiographs and MRI. ( 9541922 )
1998
22
Multiple hypothalamic factors regulate pyroglutamyl peptidase II in cultures of adenohypophyseal cells: role of the cAMP pathway. ( 9576608 )
1998
23
Lymphocytic adenohypophysitis and neurohypophysitis. ( 9187559 )
1997
24
Lymphocytic adenohypophysitis and lymphocytic infundibuloneurohypophysitis. ( 9152609 )
1997
25
Long-term clinical course of two cases of lymphocytic adenohypophysitis. ( 8930533 )
1996
26
Effects of intravenously infused pituitary adenylate cyclase-activating polypeptide on adenohypophyseal Hormone secretion in normal men. ( 8875442 )
1996
27
Differentiating lymphocytic adenohypophysitis from pituitary adenoma in the peripartum patient. ( 7623353 )
1995
28
Lymphocytic adenohypophysitis: magnetic resonance imaging features of two new cases and a review of the literature. ( 7758238 )
1995
29
Lymphocytic adenohypophysitis: contrast-enhanced MR imaging in five cases. ( 7892490 )
1995
30
Immunohistochemical demonstration of adenohypophyseal hormones during postnatal ontogenesis in the Gray Short-tailed Opossum, Monodelphis domestica (marsupialia). ( 8835137 )
1995
31
Lymphocytic Adenohypophysitis Associated with Rathke's Cleft Cyst. ( 12114815 )
1995
32
Thyrotropin-releasing hormone downregulates pyroglutamyl peptidase II activity in adenohypophyseal cells. ( 7969791 )
1994
33
[Membrane receptors and coupling proteins in adenohypophyseal cells]. ( 8242419 )
1993
34
Adenohypophyseal and sex hormones in pediatric rheumatic diseases. ( 8496873 )
1993
35
Preoperative diagnosis of lymphocytic hypophysitis (adenohypophysitis) unresponsive to short course dexamethasone: case report. ( 1545900 )
1992
36
Lymphocytic adenohypophysitis with sudden onset of diabetes insipidus in menopausal female--case report. ( 1381061 )
1992
37
Lymphocytic adenohypophysitis: a pituitary mass lesion occurring in pregnancy. Proposal for medical treatment. ( 2048602 )
1991
38
Adenohypophysitis associated with sebaceous gland atrophy in a dog. ( 1949513 )
1991
39
Lymphocytic adenohypophysitis presenting as infertility. Case report. ( 2013781 )
1991
40
Lymphocytic adenohypophysitis: an immunohistochemical study. ( 1891758 )
1991
41
[A case of pregnancy-induced lymphocytic adenohypophysitis complicated by postpartum painless thyroiditis]. ( 2070891 )
1991
42
Lymphocytic adenohypophysitis accompanying occlusion of bilateral internal carotid arteries--case report. ( 1699152 )
1990
43
Relationship between adenohypophyseal and steroid hormones and variations in serum and urinary melatonin levels during the ovarian cycle, perimenopause and menopause in healthy women. ( 2308340 )
1990
44
Twenty-four-hour rhythms in plasma concentrations of adenohypophyseal hormones are generated by distinct amplitude and/or frequency modulation of underlying pituitary secretory bursts. ( 2172282 )
1990
45
The effect of oxytocin infusion on adenohypophyseal function in man. ( 2160873 )
1990
46
Lymphocytic adenohypophysitis: report of two cases. ( 2700055 )
1989
47
Lymphocytic adenohypophysitis. Report of a case with demonstration of spontaneous tumour regression and a review of the literature. ( 3077051 )
1988
48
Lymphocytic adenohypophysitis: clinical, radiological, and magnetic resonance imaging characterization. ( 3380286 )
1988
49
A case of hypopituitarism due to granulomatous and lymphocytic adenohypophysitis with minimal pituitary enlargement: a possible variant of lymphocytic adenohypophysitis. ( 3215147 )
1988
50
Lymphocytic adenohypophysitis. ( 3278777 )
1988

Variations for Adenohypophysitis

Expression for Adenohypophysitis

Search GEO for disease gene expression data for Adenohypophysitis.

Pathways for Adenohypophysitis

GO Terms for Adenohypophysitis

Cellular components related to Adenohypophysitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 endosome lumen GO:0031904 8.96 GH1 PRL
2 secretory granule GO:0030141 8.8 POMC PRL TRH

Biological processes related to Adenohypophysitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.43 CD4 IL2RA PRL
2 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.37 CD4 GH1
3 positive regulation of T cell proliferation GO:0042102 9.32 CD4 IL2RA
4 positive regulation of JAK-STAT cascade GO:0046427 9.16 GH1 PRL
5 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 8.96 GH1 PRL
6 response to estradiol GO:0032355 8.8 CD4 GH1 PRL

Molecular functions related to Adenohypophysitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 prolactin receptor binding GO:0005148 8.96 GH1 PRL
2 hormone activity GO:0005179 8.92 GH1 POMC PRL TRH

Sources for Adenohypophysitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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