MCID: ADN015
MIFTS: 30

Adenoid Basal Cell Carcinoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Adenoid Basal Cell Carcinoma

MalaCards integrated aliases for Adenoid Basal Cell Carcinoma:

Name: Adenoid Basal Cell Carcinoma 12 14
Skin Adenoid Basal Cell Carcinoma 12
Basal Cell Carcinoma - Adenoid 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4294
UMLS 69 C1304296

Summaries for Adenoid Basal Cell Carcinoma

MalaCards based summary : Adenoid Basal Cell Carcinoma, also known as skin adenoid basal cell carcinoma, is related to cutaneous adenocystic carcinoma and jejunal cancer. An important gene associated with Adenoid Basal Cell Carcinoma is KIT (KIT Proto-Oncogene Receptor Tyrosine Kinase), and among its related pathways/superpathways are Gastric cancer and Cell cycle Role of SCF complex in cell cycle regulation. Affiliated tissues include skin and salivary gland, and related phenotypes are endocrine/exocrine gland and integument

Related Diseases for Adenoid Basal Cell Carcinoma

Diseases related to Adenoid Basal Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 206)
# Related Disease Score Top Affiliating Genes
1 cutaneous adenocystic carcinoma 29.0 B2M CEACAM5 KRT7 LALBA
2 jejunal cancer 10.5 KIT KRT7
3 intratubular embryonal carcinoma 10.5 KIT KRT7
4 pleomorphic carcinoma 10.4 KIT KRT7
5 kidney benign neoplasm 10.4 KIT KRT7
6 benign breast phyllodes tumor 10.4 KIT PGR
7 breast angiosarcoma 10.4 KIT PGR
8 uterine body mixed cancer 10.4 KIT PGR
9 cystic nephroma 10.4 KIT PGR
10 functional colonic disease 10.4 B2M KIT
11 perivascular epithelioid cell tumor 10.4 KIT PGR
12 eccrine papillary adenocarcinoma 10.4 KRT7 PGR
13 liver leiomyoma 10.4 CEACAM5 KIT
14 large cell neuroendocrine carcinoma 10.4 KIT KRT7
15 papillary hidradenoma 10.4 KIT PGR
16 endosalpingiosis 10.4 KRT7 PGR
17 female reproductive endometrioid cancer 10.4 KRT7 PGR
18 basal cell carcinoma 1 10.4
19 adenoiditis 10.4
20 basal cell carcinoma 10.4
21 fox-fordyce disease 10.4 CEACAM5 KIT
22 benign metastasizing leiomyoma 10.4 KRT7 PGR
23 spindle cell synovial sarcoma 10.4 KIT KRT7
24 renal oncocytoma 10.4 KIT KRT7
25 corneal abscess 10.4 KRT7 PGR
26 papillary serous adenocarcinoma 10.4 KRT7 PGR
27 aggressive digital papillary adenocarcinoma 10.4 CEACAM5 KIT
28 acral lentiginous melanoma 10.3 CDKN2A KIT
29 rete testis adenocarcinoma 10.3 CEACAM5 KIT
30 sertoli-leydig cell tumor 10.3 KRT7 PGR
31 cutaneous mucoepidermoid carcinoma 10.3 CEACAM5 KRT7
32 anal gland adenocarcinoma 10.3 CEACAM5 KRT7
33 inverted transitional papilloma 10.3 CDKN2A KRT7
34 small cell neuroendocrine carcinoma 10.3 CDKN2A KIT
35 cecum adenocarcinoma 10.3 B2M KRT7
36 anus adenocarcinoma 10.3 CEACAM5 KRT7
37 malignant spiradenoma 10.3 CEACAM5 KRT7
38 non-gestational choriocarcinoma 10.3 B2M PGR
39 dysgerminoma of ovary 10.3 KIT PGR
40 bile duct mucoepidermoid carcinoma 10.3 CEACAM5 KRT7
41 ovarian cystic teratoma 10.3 B2M KRT7
42 uterine carcinosarcoma 10.3 KIT PGR
43 mucinous bronchioloalveolar adenocarcinoma 10.3 CDKN2A KRT7
44 nodular hidradenoma 10.3 CEACAM5 KRT7
45 bile duct cystadenocarcinoma 10.3 CEACAM5 KRT7
46 bladder carcinoma in situ 10.3 CDKN2A KRT7
47 rete testis neoplasm 10.3 CEACAM5 KIT
48 thymus adenocarcinoma 10.3 CEACAM5 KRT7
49 colonic pseudo-obstruction 10.3 B2M KIT
50 meibomian cyst 10.3 CEACAM5 KRT7

Graphical network of the top 20 diseases related to Adenoid Basal Cell Carcinoma:



Diseases related to Adenoid Basal Cell Carcinoma

Symptoms & Phenotypes for Adenoid Basal Cell Carcinoma

MGI Mouse Phenotypes related to Adenoid Basal Cell Carcinoma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.63 B2M CDKN2A ESR1 KIT LALBA PGR
2 integument MP:0010771 9.43 B2M CDKN2A ESR1 KIT LALBA PGR
3 neoplasm MP:0002006 9.1 B2M CDKN2A ESR1 KIT PGR SPN

Drugs & Therapeutics for Adenoid Basal Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Adenoid Basal Cell Carcinoma

Genetic Tests for Adenoid Basal Cell Carcinoma

Anatomical Context for Adenoid Basal Cell Carcinoma

MalaCards organs/tissues related to Adenoid Basal Cell Carcinoma:

38
Skin, Salivary Gland

Publications for Adenoid Basal Cell Carcinoma

Articles related to Adenoid Basal Cell Carcinoma:

# Title Authors Year
1
Adenoid basal cell carcinoma: a rare facet of basal cell carcinoma. ( 27095806 )
2016
2
CD117 and CD43 are useful adjuncts in the distinction of adenoid cystic carcinoma from adenoid basal cell carcinoma. ( 25551301 )
2015
3
Coexistence of Solid (Nodular) and Differentiated (Adenoid) Basal Cell Carcinoma at the Same Anatomical Site. ( 26538745 )
2015
4
Adenoid basal cell carcinoma and its mimics. ( 23723508 )
2013
5
Adenoid Basal cell carcinoma simulating ameloblastoma. ( 19549180 )
2009
6
A Case of Axillary Adenoid Basal Cell Carcinoma. ( 27303153 )
2008
7
Tenascin expression in adenoid basal cell carcinoma of the skin. ( 8615597 )
1996
8
Giant adenoid basal cell carcinoma. ( 8060083 )
1994
9
Primary adenoid cystic carcinoma of the skin. A clinical, histological, and immunocytochemical comparison with adenoid cystic carcinoma of salivary glands and adenoid basal cell carcinoma. ( 3010759 )
1986
10
Adenoid basal cell carcinoma of the vulva. ( 7185765 )
1982

Variations for Adenoid Basal Cell Carcinoma

Cosmic variations for Adenoid Basal Cell Carcinoma:

9 (show top 50) (show all 225)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1 COSM43635 TP53 skin,NS,carcinoma,basal cell carcinoma c.536A>T p.H179L 9
2 COSM44097 TP53 skin,NS,carcinoma,basal cell carcinoma c.530C>T p.P177L 9
3 COSM43920 TP53 skin,NS,carcinoma,basal cell carcinoma c.680C>T p.S227F 9
4 COSM43582 TP53 skin,NS,carcinoma,basal cell carcinoma c.454C>T p.P152S 9
5 COSM10812 TP53 skin,NS,carcinoma,basal cell carcinoma c.722C>T p.S241F 9
6 COSM45734 TP53 skin,NS,carcinoma,basal cell carcinoma c.622G>T p.D208Y 9
7 COSM44096 TP53 skin,NS,carcinoma,basal cell carcinoma c.748C>G p.P250A 9
8 COSM43616 TP53 skin,NS,carcinoma,basal cell carcinoma c.704A>G p.N235S 9
9 COSM43596 TP53 skin,NS,carcinoma,basal cell carcinoma c.841G>A p.D281N 9
10 COSM10656 TP53 skin,NS,carcinoma,basal cell carcinoma c.742C>T p.R248W 9
11 COSM44310 TP53 skin,NS,carcinoma,basal cell carcinoma c.738G>A p.M246I 9
12 COSM11084 TP53 skin,NS,carcinoma,basal cell carcinoma c.517G>A p.V173M 9
13 COSM45138 TP53 skin,NS,carcinoma,basal cell carcinoma c.853G>C p.E285Q 9
14 COSM43700 TP53 skin,NS,carcinoma,basal cell carcinoma c.712T>A p.C238S 9
15 COSM10768 TP53 skin,NS,carcinoma,basal cell carcinoma c.535C>T p.H179Y 9
16 COSM10887 TP53 skin,NS,carcinoma,basal cell carcinoma c.833C>G p.P278R 9
17 COSM44241 TP53 skin,NS,carcinoma,basal cell carcinoma c.592G>T p.E198* 9
18 COSM10660 TP53 skin,NS,carcinoma,basal cell carcinoma c.818G>A p.R273H 9
19 COSM45751 TP53 skin,NS,carcinoma,basal cell carcinoma c.511G>C p.E171Q 9
20 COSM44130 TP53 skin,NS,carcinoma,basal cell carcinoma c.477C>T p.A159A 9
21 COSM10705 TP53 skin,NS,carcinoma,basal cell carcinoma c.586C>T p.R196* 9
22 COSM10728 TP53 skin,NS,carcinoma,basal cell carcinoma c.839G>A p.R280K 9
23 COSM43842 TP53 skin,NS,carcinoma,basal cell carcinoma c.770T>C p.L257P 9
24 COSM43695 TP53 skin,NS,carcinoma,basal cell carcinoma c.748C>T p.P250S 9
25 COSM11376 TP53 skin,NS,carcinoma,basal cell carcinoma c.737T>G p.M246R 9
26 COSM10704 TP53 skin,NS,carcinoma,basal cell carcinoma c.844C>T p.R282W 9
27 COSM10939 TP53 skin,NS,carcinoma,basal cell carcinoma c.832C>T p.P278S 9
28 COSM10662 TP53 skin,NS,carcinoma,basal cell carcinoma c.743G>A p.R248Q 9
29 COSM45074 TP53 skin,NS,carcinoma,basal cell carcinoma c.829T>G p.C277G 9
30 COSM10863 TP53 skin,NS,carcinoma,basal cell carcinoma c.833C>T p.P278L 9
31 COSM45739 TP53 skin,NS,carcinoma,basal cell carcinoma c.677G>C p.G226A 9
32 COSM45322 TP53 skin,NS,carcinoma,basal cell carcinoma c.757A>G p.T253A 9
33 COSM44606 TP53 skin,NS,carcinoma,basal cell carcinoma c.665C>T p.P222L 9
34 COSM44295 TP53 skin,NS,carcinoma,basal cell carcinoma c.993+1G>A p.? 9
35 COSM10650 TP53 skin,NS,carcinoma,basal cell carcinoma c.529C>T p.P177S 9
36 COSM43665 TP53 skin,NS,carcinoma,basal cell carcinoma c.746G>C p.R249T 9
37 COSM45774 TP53 skin,NS,carcinoma,basal cell carcinoma c.899C>G p.P300R 9
38 COSM10749 TP53 skin,NS,carcinoma,basal cell carcinoma c.830G>T p.C277F 9
39 COSM11449 TP53 skin,NS,carcinoma,basal cell carcinoma c.388C>T p.L130F 9
40 COSM10771 TP53 skin,NS,carcinoma,basal cell carcinoma c.749C>T p.P250L 9
41 COSM44068 TP53 skin,NS,carcinoma,basal cell carcinoma c.532C>A p.H178N 9
42 COSM11152 TP53 skin,NS,carcinoma,basal cell carcinoma c.700T>C p.Y234H 9
43 COSM45834 TP53 skin,NS,carcinoma,basal cell carcinoma c.409C>A p.L137M 9
44 COSM10905 TP53 skin,NS,carcinoma,basal cell carcinoma c.451C>T p.P151S 9
45 COSM10654 TP53 skin,NS,carcinoma,basal cell carcinoma c.637C>T p.R213* 9
46 COSM6932 TP53 skin,NS,carcinoma,basal cell carcinoma c.733G>A p.G245S 9
47 COSM45424 TP53 skin,NS,carcinoma,basal cell carcinoma c.781A>T p.S261C 9
48 COSM10659 TP53 skin,NS,carcinoma,basal cell carcinoma c.817C>T p.R273C 9
49 COSM10794 TP53 skin,NS,carcinoma,basal cell carcinoma c.796G>A p.G266R 9
50 COSM10648 TP53 skin,NS,carcinoma,basal cell carcinoma c.524G>A p.R175H 9

Expression for Adenoid Basal Cell Carcinoma

Search GEO for disease gene expression data for Adenoid Basal Cell Carcinoma.

Pathways for Adenoid Basal Cell Carcinoma

Pathways related to Adenoid Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.92 CDKN2A ESR1 KIT PGR
2
Show member pathways
11.58 CDKN2A ESR1 PGR
3 10.86 CEACAM5 KIT SPN

GO Terms for Adenoid Basal Cell Carcinoma

Biological processes related to Adenoid Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 stem cell differentiation GO:0048863 9.26 ESR1 KIT
2 response to cadmium ion GO:0046686 9.16 B2M KIT
3 somatic stem cell division GO:0048103 8.96 CDKN2A KIT
4 positive regulation of phospholipase C activity GO:0010863 8.62 ESR1 KIT

Molecular functions related to Adenoid Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear receptor activity GO:0004879 8.96 ESR1 PGR
2 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Adenoid Basal Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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