Aliases & Classifications for Adenoiditis

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Aliases & Descriptions for Adenoiditis:

Name: Adenoiditis 11 13 68
 
Chronic Adenoiditis 11 68

Classifications:



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Disease Ontology11 DOID:0050145
ICD1030 J35.02
ICD9CM32 474.01

Summaries for Adenoiditis

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Disease Ontology:11 An upper respiratory tract disease which involves inflammation, pain, and swelling of the adenoid tissue due to the infection by bacteria and viruses. It occurs primarily in children and may be secondary to an allergy, infection of nose or throat and an obstruction of the eustachian tube. The infection has symptom pain, has symptom redness, has symptom swelling, and has symptom difficulty swallowing.

MalaCards based summary: Adenoiditis, also known as chronic adenoiditis, is related to adenoid hypertrophy and salivary gland adenoid cystic carcinoma, and has symptoms including pain, redness and swelling. An important gene associated with Adenoiditis is FCN2 (Ficolin 2), and among its related pathways is Tuberculosis. Affiliated tissues include salivary gland, breast and lung, and related mouse phenotypes are Increased shRNA abundance (Z-score > 2) and hematopoietic system.

Wikipedia:71 Adenoiditis is the inflammation of the adenoid tissue, usually caused by an infection. Adenoiditis is... more...

Related Diseases for Adenoiditis

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Diseases related to Adenoiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 161)
idRelated DiseaseScoreTop Affiliating Genes
1adenoid hypertrophy12.3
2salivary gland adenoid cystic carcinoma12.2
3cervical adenoid cystic carcinoma11.9
4maxillary sinus adenoid cystic carcinoma11.9
5lacrimal gland adenoid cystic carcinoma11.9
6adenoid basal cell carcinoma11.9
7breast adenoid cystic carcinoma11.9
8esophageal adenoid cystic carcinoma11.9
9laryngeal adenoid cystic carcinoma11.9
10bartholin's gland adenoid cystic carcinoma11.9
11adenoid squamous cell carcinoma11.9
12prostate adenoid cystic carcinoma11.8
13lung adenoid cystic carcinoma11.8
14trachea adenoid cystic carcinoma11.8
15ethmoid sinus adenoid cystic carcinoma11.8
16adenoid basal carcinoma of the cervix uteri11.7
17parotid gland adenoid cystic carcinoma11.7
18lymph node adenoid cystic carcinoma11.7
19cervical adenoid basal carcinoma11.7
20adenoid cystic carcinoma of the corpus uteri11.7
21sublingual gland adenoid cystic carcinoma11.6
22tonsillitis11.5
23multiple familial trichoepithelioma11.4
24trichoepithelioma, multiple familial, 111.3
25sleep apnea11.1
26paranasal sinus cancer11.0
27cutaneous adenocystic carcinoma11.0
28prostate cancer 110.7
29prostate cancer10.7
30prostate cancer, hereditary, 1210.7
31prostate cancer, hereditary, 1310.7
32prostate cancer, hereditary, 210.7
33prostate cancer, hereditary, 1110.7
34plague10.7
35ceruminous carcinoma10.7
36calcifying epithelial odontogenic tumor10.7
37squamous cell carcinoma10.3
38adenocarcinoma10.2
39polymorphous low-grade adenocarcinoma10.2
40otitis media10.2
41adenoma10.2
42basal cell carcinoma10.1
43pleomorphic adenoma10.1
44chronic conjunctivitis10.0
45mucoepidermoid carcinoma10.0
46nasopharyngitis9.9
47endotheliitis9.9
48sinusitis9.9
49cervicitis9.9
50laryngitis9.9

Graphical network of the top 20 diseases related to Adenoiditis:



Diseases related to adenoiditis

Symptoms & Phenotypes for Adenoiditis

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Symptoms:

 11 (show all 4)
  • pain
  • redness
  • swelling
  • difficulty swallowing

GenomeRNAi Phenotypes related to Adenoiditis according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-1929.3LY75, TYROBP

MGI Mouse Phenotypes related to Adenoiditis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.4CARD9, CLEC7A, CNOT4, LY75, TYROBP
2MP:00053878.4CARD9, CLEC7A, CNOT4, LY75, TYROBP

Drugs & Therapeutics for Adenoiditis

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Drugs for Adenoiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Dexmedetomidineapproved, vet_approvedPhase 459276631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
2Hypnotics and SedativesPhase 42616
3Neurotransmitter AgentsPhase 418340
4Peripheral Nervous System AgentsPhase 423689
5Pharmaceutical SolutionsPhase 48192
6Central Nervous System DepressantsPhase 413403
7Analgesics, Non-NarcoticPhase 46501
8Adrenergic AgonistsPhase 43027
9Adrenergic alpha-2 Receptor AgonistsPhase 4980
10Adrenergic alpha-AgonistsPhase 41734
11AnalgesicsPhase 411733
12Adrenergic AgentsPhase 45352

Interventional clinical trials:

idNameStatusNCT IDPhase
1The Effect of Dexmedetomidine on Airway Complications After Deep or Awake ExtubationRecruitingNCT02162433Phase 4

Search NIH Clinical Center for Adenoiditis

Genetic Tests for Adenoiditis

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Anatomical Context for Adenoiditis

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MalaCards organs/tissues related to Adenoiditis:

36
Salivary gland, Breast, Lung, Tonsil, Trachea, Skin, Tongue

Publications for Adenoiditis

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Articles related to Adenoiditis:

(show top 50)    (show all 1008)
idTitleAuthorsYear
1
c-Myb Overexpression in Cytology Smears of Tracheobronchial and Pulmonary Adenoid Cystic Carcinomas. (27974718)
2017
2
Downregulation of miR-222 Induces Apoptosis and Cellular Migration in Adenoid Cystic Carcinoma Cells. (28277192)
2017
3
HIF1I+ in Tumorigenesis of Adenoid Cystic Carcinoma. (28179306)
2017
4
Intra-arterial Chemotherapy for Lacrimal Gland Adenoid Cystic Carcinoma. (27898620)
2017
5
The unique luminal staining pattern of cytokeratin 5/6 in adenoid cystic carcinoma of the breast may aid in differentiating it from its mimickers. (27240462)
2016
6
Expression of SKA1 and MMP-9 in primary salivary adenoid cystic carcinoma: Correlation with tumor progression and patient prognosis. (26881872)
2016
7
Application of p16 Immunohistochemistry and RNA In Situ Hybridization in the Classification of Adenoid Basal Tumors of the Cervix. (26352551)
2016
8
PRL-3 promotes migration and invasion and is associated with poor prognosis in salivary adenoid cystic carcinoma. (26041460)
2016
9
Re-affirming the necessity of sending even minor surgical specimens for histopathology: a case of inverted papilloma of the adenoids. (27685930)
2016
10
FCN2 c.772G>T polymorphism is associated with chronic adenoiditis and/or tonsillitis, but notA -4 A>G andA -602A G>A. (27368434)
2016
11
Myoepithelial differentiation in cribriform, tubular and solid pattern of adenoid cystic carcinoma: A potential involvement in histological grading and prognosis. (27180054)
2016
12
MYB expression: Potential role in separating adenoid cystic carcinoma (ACC) from pleomorphic adenoma (PA). (27491495)
2016
13
Adenoid cystic carcinoma presenting as an orbital apex mass with intracranial extension. (27085282)
2016
14
Does adenoid hypertrophy affect disease severity in children with allergic rhinitis? (27405740)
2016
15
Adenoid Cystic Carcinoma of Trachea: A Diagnostic and Therapeutic Challenge. (27066420)
2016
16
Association between clinical features, treatment, and recurrence rate of adenoid cystic carcinoma of the palate: a 10-year retrospective study. (27094499)
2016
17
Laryngeal Adenoid Cystic Carcinoma: A Systematic Review. (26701176)
2016
18
Clinical utility of myb rearrangement detection and p63/p40 immunophenotyping in the diagnosis of adenoid cystic carcinoma of minor salivary glands: a pilot study. (26711711)
2016
19
Differing Lymphatic Vessels Density in Salivary Adenoid Cystic Carcinoma and Pleomorphic Adenoma. (27837476)
2016
20
Downregulation of nucleophosmin expression inhibited proliferation and induced apoptosis in salivary gland adenoid cystic carcinoma. (27501253)
2016
21
Adenoid hypertrophy and chronic rhinosinusitis: Helicobacter pylori on antral lavages, adenoid tissue and salival inmunoglobuline A on paediatric patients. (26746618)
2016
22
EphA2 silencing promotes growth, migration, and metastasis in salivary adenoid cystic carcinoma: in vitro and in vivo study. (27186278)
2016
23
Bmi-1 expression predicts prognosis in salivary adenoid cystic carcinoma and correlates with epithelial-mesenchymal transition-related factors. (27180058)
2016
24
Carcinoma-Associated Fibroblasts Lead the Invasion of Salivary Gland Adenoid Cystic Carcinoma Cells by Creating an Invasive Track. (26954362)
2016
25
Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma. (26862087)
2016
26
SOD2 deregulation enhances migration, invasion and has poor prognosis in salivary adenoid cystic carcinoma. (27181103)
2016
27
Adenoid basal cell carcinoma: a rare facet of basal cell carcinoma. (27095806)
2016
28
MicroRNA-144-3p inhibits proliferation and induces apoptosis of human salivary adenoid carcinoma cells via targeting of mTOR. (26687302)
2016
29
Definitive Radiotherapy for Skin and Adenoid Cystic Carcinoma with Perineural Invasion. (27123393)
2016
30
The common genetic variants of toll-like receptor and susceptibilityto adenoid hypertrophy: a hospital-based cohort study. (27966312)
2016
31
Expression of Submaxillary Gland Androgen-regulated Protein 3A (SMR3A) in Adenoid Cystic Carcinoma of the Head and Neck. (26851015)
2016
32
The effect of adenoid hypertrophy on maxillofacial development: an objective photographic analysis. (27647047)
2016
33
1,25-Dihydroxyvitamin D3 alleviates salivary adenoid cystic carcinoma progression by suppressing GPX1 expression through the NF-I_B pathway. (26782341)
2016
34
Well-differentiated fetal adenocarcinoma of the lung mimicking adenoid cystic carcinoma on fine needle aspiration: A case report. (27374425)
2016
35
Primary Mediastinal Synovial Sarcoma with subsequent development of Primary Adenoid Cystic Carcinoma of Lung presenting as superior vena cava syndrome. (26992072)
2016
36
Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review. (27084720)
2016
37
Expression of Autophagy and Reactive Oxygen Species-Related Proteins in Lacrimal Gland Adenoid Cystic Carcinoma. (26847304)
2016
38
Accuracy and reliability of orthodontists using cone-beam computerized tomography for assessment of adenoid hypertrophy. (27871704)
2016
39
Inhibitory effects of silibinin on proliferation and lung metastasis of human high metastasis cell line of salivary gland adenoid cystic carcinoma via autophagy induction. (27822066)
2016
40
Type III TGF-I^ receptor inhibits cell proliferation and migration in salivary glands adenoid cystic carcinoma by suppressing NF-I_B signaling. (26531330)
2016
41
Nonencapsulated Streptococcus pneumoniae as a cause of chronic adenoiditis. (27144125)
2016
42
The effect of adenoid hypertrophy and adenoidectomy in patients on cardiovascular risk reduction. (27405084)
2016
43
Adding concurrent chemotherapy to postoperative radiotherapy improves locoregional control but Not overall survival in patients with salivary gland adenoid cystic carcinoma-a propensity score matched study. (27000157)
2016
44
Sporadic Burkitt Lymphoma Presenting as Acute Pancreatitis, Concurrent Sinusitis, and Enlarged Adenoids. (27213067)
2016
45
Fine-Needle Aspiration of Epithelial-Myoepithelial Carcinoma of the Parotid Gland With Prominent Adenoid Cystic Carcinoma-Like Cribriform Features: Avoiding a Diagnostic Pitfall. (27614667)
2016
46
Twist Expression in Pleomorphic Adenoma, Adenoid Cystic Carcinoma and Mucoepidermoid Carcinoma of Salivary Glands. (26832177)
2016
47
In Vivo Visualization of Prostate-Specific Membrane Antigen in Adenoid Cystic Carcinoma of the Salivary Gland. (27055136)
2016
48
Adenoid Cystic Carcinoma of the Trachea. (27065684)
2016
49
Tympanometric Findings among Children with Adenoid Hypertrophy in Port Harcourt, Nigeria. (27563311)
2016
50
Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screening. (27212063)
2016

Variations for Adenoiditis

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Expression for genes affiliated with Adenoiditis

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Search GEO for disease gene expression data for Adenoiditis.

Pathways for genes affiliated with Adenoiditis

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Pathways related to Adenoiditis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.1CARD9, CLEC7A

GO Terms for genes affiliated with Adenoiditis

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Biological processes related to Adenoiditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1defense response to Gram-positive bacteriumGO:005083010.2CARD9, FCN2
2immune system processGO:00023769.4CARD9, CLEC7A, FCN2
3stimulatory C-type lectin receptor signaling pathwayGO:00022239.1CARD9, CLEC7A
4innate immune responseGO:00450878.6CARD9, CLEC7A, FCN2, TYROBP

Molecular functions related to Adenoiditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1carbohydrate bindingGO:00302468.7CLEC7A, FCN2, LY75

Sources for Adenoiditis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet