Aliases & Classifications for Adenoiditis

About this section

Aliases & Descriptions for Adenoiditis:

Name: Adenoiditis 11 13 68
 
Chronic Adenoiditis 11 68

Classifications:



External Ids:

Disease Ontology11 DOID:0050145
ICD1030 J35.02
ICD9CM32 474.01

Summaries for Adenoiditis

About this section
Disease Ontology:11 An upper respiratory tract disease which involves inflammation, pain, and swelling of the adenoid tissue due to the infection by bacteria and viruses. It occurs primarily in children and may be secondary to an allergy, infection of nose or throat and an obstruction of the eustachian tube. The infection has symptom pain, has symptom redness, has symptom swelling, and has symptom difficulty swallowing.

MalaCards based summary: Adenoiditis, also known as chronic adenoiditis, is related to chronic conjunctivitis and adenoid hypertrophy, and has symptoms including pain, redness and swelling. An important gene associated with Adenoiditis is FCN2 (Ficolin 2), and among its related pathways are CLEC7A (Dectin-1) signaling and Tuberculosis. Affiliated tissues include salivary gland, breast and lung, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and Increased shRNA abundance (Z-score > 2).

Wikipedia:71 Adenoiditis is the inflammation of the adenoid tissue, usually caused by an infection. Adenoiditis is... more...

Related Diseases for Adenoiditis

About this section

Diseases related to Adenoiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 152)
idRelated DiseaseScoreTop Affiliating Genes
1chronic conjunctivitis29.2CARD9, CLEC7A
2adenoid hypertrophy12.4
3salivary gland adenoid cystic carcinoma12.2
4cervical adenoid cystic carcinoma11.9
5maxillary sinus adenoid cystic carcinoma11.9
6lacrimal gland adenoid cystic carcinoma11.9
7adenoid basal cell carcinoma11.9
8breast adenoid cystic carcinoma11.9
9esophageal adenoid cystic carcinoma11.9
10laryngeal adenoid cystic carcinoma11.9
11bartholin's gland adenoid cystic carcinoma11.9
12adenoid squamous cell carcinoma11.9
13prostate adenoid cystic carcinoma11.8
14lung adenoid cystic carcinoma11.8
15trachea adenoid cystic carcinoma11.8
16ethmoid sinus adenoid cystic carcinoma11.8
17adenoid basal carcinoma of the cervix uteri11.7
18parotid gland adenoid cystic carcinoma11.7
19lymph node adenoid cystic carcinoma11.7
20cervical adenoid basal carcinoma11.7
21adenoid cystic carcinoma of the corpus uteri11.7
22sublingual gland adenoid cystic carcinoma11.6
23multiple familial trichoepithelioma11.4
24trichoepithelioma, multiple familial, 111.3
25paranasal sinus cancer11.0
26cutaneous adenocystic carcinoma11.0
27prostate cancer 110.7
28prostate cancer10.7
29prostate cancer, hereditary, 1210.7
30prostate cancer, hereditary, 1310.7
31prostate cancer, hereditary, 210.7
32prostate cancer, hereditary, 1110.7
33plague10.7
34ceruminous carcinoma10.7
35calcifying epithelial odontogenic tumor10.7
36tonsillitis10.6
37adenocarcinoma10.2
38polymorphous low-grade adenocarcinoma10.2
39otitis media10.2
40adenoma10.1
41basal cell carcinoma10.1
42pleomorphic adenoma10.1
43mucoepidermoid carcinoma10.0
44nasopharyngitis10.0
45endotheliitis10.0
46sinusitis9.9
47laryngitis9.9
48cervicitis9.9
49rhinitis9.9
50allergic rhinitis9.9

Graphical network of the top 20 diseases related to Adenoiditis:



Diseases related to adenoiditis

Symptoms & Phenotypes for Adenoiditis

About this section

Symptoms:

 11 (show all 4)
  • pain
  • redness
  • swelling
  • difficulty swallowing

UMLS symptoms related to Adenoiditis:


pain of lymph node

GenomeRNAi Phenotypes related to Adenoiditis according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-589.0CARD9, CNOT4
2GR00366-A-359.0CARD9, TYROBP

Drugs & Therapeutics for Adenoiditis

About this section

Drugs for Adenoiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Dexmedetomidineapproved, vet_approvedPhase 454076631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
2Hypnotics and SedativesPhase 42485
3Neurotransmitter AgentsPhase 417734
4Peripheral Nervous System AgentsPhase 422776
5Pharmaceutical SolutionsPhase 47793
6Central Nervous System DepressantsPhase 412806
7Analgesics, Non-NarcoticPhase 46260
8Adrenergic AgonistsPhase 42877
9Adrenergic alpha-2 Receptor AgonistsPhase 4911
10Adrenergic alpha-AgonistsPhase 41625
11AnalgesicsPhase 411287
12Adrenergic AgentsPhase 45140

Interventional clinical trials:

idNameStatusNCT IDPhase
1The Effect of Dexmedetomidine on Airway Complications After Deep or Awake ExtubationRecruitingNCT02162433Phase 4

Search NIH Clinical Center for Adenoiditis

Genetic Tests for Adenoiditis

About this section

Anatomical Context for Adenoiditis

About this section

MalaCards organs/tissues related to Adenoiditis:

36
Salivary gland, Breast, Lung, Tonsil, Trachea, Skin, Tongue

Publications for Adenoiditis

About this section

Articles related to Adenoiditis:

(show top 50)    (show all 977)
idTitleAuthorsYear
1
Adenoid cystic carcinoma of the lacrimal gland: rarea88a8 (23823505)
88lethala88a
2
Intra-arterial Chemotherapy for Lacrimal Gland Adenoid Cystic Carcinoma. (27898620)
2017
3
Type III TGF-I^ receptor inhibits cell proliferation and migration in salivary glands adenoid cystic carcinoma by suppressing NF-I_B signaling. (26531330)
2016
4
Well-differentiated fetal adenocarcinoma of the lung mimicking adenoid cystic carcinoma on fine needle aspiration: A case report. (27374425)
2016
5
Tympanometric Findings among Children with Adenoid Hypertrophy in Port Harcourt, Nigeria. (27563311)
2016
6
Carcinoma-Associated Fibroblasts Lead the Invasion of Salivary Gland Adenoid Cystic Carcinoma Cells by Creating an Invasive Track. (26954362)
2016
7
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma. (26829750)
2016
8
The effect of adenoid hypertrophy and adenoidectomy in patients on cardiovascular risk reduction. (27405084)
2016
9
The relationship of enuresis nocturna and adenoid hypertrophy. (27377086)
2016
10
An infrequent histopathological subtype of ameloblastoma: Adenoid granular cell ameloblastoma with dentinoid. (27605998)
2016
11
Accuracy and reliability of oral maxillofacial radiologists when evaluating cone-beam computed tomography imaging for adenoid hypertrophy screening: a comparison with nasopharyngoscopy. (27181449)
2016
12
Accuracy and reliability of orthodontists using cone-beam computerized tomography for assessment of adenoid hypertrophy. (27871704)
2016
13
MYB expression: Potential role in separating adenoid cystic carcinoma (ACC) from pleomorphic adenoma (PA). (27491495)
2016
14
Differing Lymphatic Vessels Density in Salivary Adenoid Cystic Carcinoma and Pleomorphic Adenoma. (27837476)
2016
15
Adenoid Cystic Carcinoma Metastatic to the Pituitary: A Case Report and Discussion of Potential Diagnostic Value of Magnetic Resonance Elastography in Pituitary Tumors. (27018011)
2016
16
Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screening. (27212063)
2016
17
MRI of nasopharyngeal adenoid hypertrophy. (27531860)
2016
18
Effect of adenoid hypertrophy and pulmonary function tests in children with mild asthma. (27888821)
2016
19
FZD2 inhibits the cell growth and migration of salivary adenoid cystic carcinomas. (25695658)
2016
20
1,25-Dihydroxyvitamin D3 alleviates salivary adenoid cystic carcinoma progression by suppressing GPX1 expression through the NF-I_B pathway. (26782341)
2016
21
Laryngeal Adenoid Cystic Carcinoma: A Systematic Review. (26701176)
2016
22
Re-affirming the necessity of sending even minor surgical specimens for histopathology: a case of inverted papilloma of the adenoids. (27685930)
2016
23
Pleomorphic adenoma and adenoid cystic carcinoma of salivary glands: E-cadherin immunoexpression and analysis of the CDH1 -160C/A polymorphism. (27665273)
2016
24
Inhibitory effects of silibinin on proliferation and lung metastasis of human high metastasis cell line of salivary gland adenoid cystic carcinoma via autophagy induction. (27822066)
2016
25
Endoscopic and clinical benefits of hyaluronic acid in children with chronic adenoiditis and middle ear disease. (27695944)
2016
26
Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma. (26862087)
2016
27
Fine-Needle Aspiration of Epithelial-Myoepithelial Carcinoma of the Parotid Gland With Prominent Adenoid Cystic Carcinoma-Like Cribriform Features: Avoiding a Diagnostic Pitfall. (27614667)
2016
28
MicroRNA-144-3p inhibits proliferation and induces apoptosis of human salivary adenoid carcinoma cells via targeting of mTOR. (26687302)
2016
29
Adenoid hypertrophy and chronic rhinosinusitis: Helicobacter pylori on antral lavages, adenoid tissue and salival inmunoglobuline A on paediatric patients. (26746618)
2016
30
FCN2 c.772G>T polymorphism is associated with chronic adenoiditis and/or tonsillitis, but notA -4 A>G andA -602A G>A. (27368434)
2016
31
Primary Mediastinal Synovial Sarcoma with subsequent development of Primary Adenoid Cystic Carcinoma of Lung presenting as superior vena cava syndrome. (26992072)
2016
32
Expression of Autophagy and Reactive Oxygen Species-Related Proteins in Lacrimal Gland Adenoid Cystic Carcinoma. (26847304)
2016
33
Adding concurrent chemotherapy to postoperative radiotherapy improves locoregional control but Not overall survival in patients with salivary gland adenoid cystic carcinoma-a propensity score matched study. (27000157)
2016
34
The effect of adenoid hypertrophy on maxillofacial development: an objective photographic analysis. (27647047)
2016
35
Sporadic Burkitt Lymphoma Presenting as Acute Pancreatitis, Concurrent Sinusitis, and Enlarged Adenoids. (27213067)
2016
36
Primary effusion lymphoma involving cerebrospinal fluid, deep cervical lymph nodes and adenoids. Report of a case supporting the lymphatic connection between brain and lymph nodes. (27862361)
2016
37
Notch2 signaling contributes to cell growth, invasion, and migration in salivary adenoid cystic carcinoma. (26427670)
2016
38
Integrative versus Conventional Therapy of Chronic Otitis Media with Effusion and Adenoid Hypertrophy in Children: A Prospective Observational Study. (27607438)
2016
39
Expression of Submaxillary Gland Androgen-regulated Protein 3A (SMR3A) in Adenoid Cystic Carcinoma of the Head and Neck. (26851015)
2016
40
Expression of LC3, LAMP2, KEAP1 and NRF2 in Salivary Adenoid Cystic Carcinoma. (26350055)
2016
41
Novel MYBL1 Gene Rearrangements with Recurrent MYBL1-NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations. (26631609)
2016
42
Adenoid basal cell carcinoma: a rare facet of basal cell carcinoma. (27095806)
2016
43
Recurrent Fusions in MYB and MYBL1 Define a Common, Transcription Factor-Driven Oncogenic Pathway in Salivary Gland Adenoid Cystic Carcinoma. (26631070)
2016
44
Clinical utility of myb rearrangement detection and p63/p40 immunophenotyping in the diagnosis of adenoid cystic carcinoma of minor salivary glands: a pilot study. (26711711)
2016
45
Does adenoid hypertrophy affect disease severity in children with allergic rhinitis? (27405740)
2016
46
Cutaneous Metastasis of Breast Adenoid Cystic Carcinoma to the Scalp. (26968987)
2016
47
The common genetic variants of toll-like receptor and susceptibilityto adenoid hypertrophy: a hospital-based cohort study. (27966312)
2016
48
PRL-3 promotes migration and invasion and is associated with poor prognosis in salivary adenoid cystic carcinoma. (26041460)
2016
49
PAK2 promotes migration and proliferation of salivary gland adenoid cystic carcinoma. (27648129)
2016
50
Downregulation of nucleophosmin expression inhibited proliferation and induced apoptosis in salivary gland adenoid cystic carcinoma. (27501253)
2016

Variations for Adenoiditis

About this section

Expression for genes affiliated with Adenoiditis

About this section
Search GEO for disease gene expression data for Adenoiditis.

Pathways for genes affiliated with Adenoiditis

About this section

Pathways related to Adenoiditis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.3CARD9, CLEC7A
29.3CARD9, CLEC7A
38.5CARD9, CLEC7A, TYROBP
4
Show member pathways
8.1CARD9, CLEC7A, FCN2, TYROBP

GO Terms for genes affiliated with Adenoiditis

About this section

Biological processes related to Adenoiditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1defense response to Gram-positive bacteriumGO:005083010.1CARD9, FCN2
2stimulatory C-type lectin receptor signaling pathwayGO:00022239.3CARD9, CLEC7A
3innate immune responseGO:00450879.0CARD9, CLEC7A, TYROBP

Sources for Adenoiditis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet