Aliases & Classifications for Adenoiditis

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Aliases & Descriptions for Adenoiditis:

Name: Adenoiditis 10 12 65
 
Chronic Adenoiditis 10 65

Classifications:



External Ids:

Disease Ontology10 DOID:0050145
ICD1027 J35.02
ICD9CM29 474.01
UMLS65 C0396023, C0001427

Summaries for Adenoiditis

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Disease Ontology:10 An upper respiratory tract disease which involves inflammation, pain, and swelling of the adenoid tissue due to the infection by bacteria and viruses. It occurs primarily in children and may be secondary to an allergy, infection of nose or throat and an obstruction of the eustachian tube. The infection has symptom pain, has symptom redness, has symptom swelling, and has symptom difficulty swallowing.

MalaCards based summary: Adenoiditis, also known as chronic adenoiditis, is related to chronic conjunctivitis and purpura, and has symptoms including pain, redness and swelling. An important gene associated with Adenoiditis is CARD9 (Caspase Recruitment Domain Family Member 9), and among its related pathways are Atypical NF-kappaB pathway and ICos-ICosL Pathway in T-Helper Cell. Affiliated tissues include endothelial, breast and bone, and related mouse phenotypes are endocrine/exocrine gland and cellular.

Wikipedia:68 Adenoiditis is the inflammation of the adenoid tissue, usually caused by an infection. Adenoiditis is... more...

Related Diseases for Adenoiditis

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Diseases related to Adenoiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 619)
idRelated DiseaseScoreTop Affiliating Genes
1chronic conjunctivitis31.3CD79A, LTF, TSPO
2purpura30.6CD40LG, CD79A
3meckel's diverticulum30.4CD79A, LTF
4cryopyrin-associated periodic syndrome30.4CD40LG, CD79A
5cystitis30.4CD40LG, CD79A
6megakaryocytic leukemia30.4BCL10, CD40LG, MALT1
7acute diarrhea30.3CARD9, SYK
8otomycosis24.5BCL10, CARD9, CD209, CD40LG, CD68, CD69
9adenoid hypertrophy12.6
10salivary gland adenoid cystic carcinoma12.5
11cervical adenoid cystic carcinoma12.3
12prostate adenoid cystic carcinoma12.3
13lung adenoid cystic carcinoma12.3
14trachea adenoid cystic carcinoma12.3
15maxillary sinus adenoid cystic carcinoma12.3
16ethmoid sinus adenoid cystic carcinoma12.3
17adenoid basal cell carcinoma12.3
18lacrimal gland adenoid cystic carcinoma12.3
19breast adenoid cystic carcinoma12.3
20esophageal adenoid cystic carcinoma12.3
21laryngeal adenoid cystic carcinoma12.3
22bartholin's gland adenoid cystic carcinoma12.3
23adenoid basal carcinoma of the cervix uteri12.3
24parotid gland adenoid cystic carcinoma12.2
25lymph node adenoid cystic carcinoma12.2
26adenoid squamous cell carcinoma12.2
27cervical adenoid basal carcinoma12.2
28adenoid cystic carcinoma of the corpus uteri12.2
29sublingual gland adenoid cystic carcinoma12.2
30multiple familial trichoepithelioma11.7
31trichoepithelioma, multiple familial, 111.5
32paranasal sinus cancer11.5
33cutaneous adenocystic carcinoma11.5
34tonsillitis10.8
35prostate cancer10.7
36primary cutaneous gamma/delta-positive t-cell lymphoma10.5BCL10, MALT1
37bard1-related susceptibility to breast cancer10.5BCL10, MALT1
38typhus10.5CD40LG, CD79A
39pulmonary edema10.5CD40LG, CD79A
40congenital hypogammaglobulinemia10.5CD40LG, CD79A
41calabro syndrome10.5CD40LG, CD79A
42gamma heavy chain disease10.5CD40LG, CD79A
43exanthema subitum10.5CD40LG, CD79A
44osteomalacia10.5CD40LG, CD79A
45epidermolysis bullosa simplex10.5CD40LG, CD79A
46proliferative glomerulonephritis10.5CD40LG, CD79A
47acute salpingitis10.5CD40LG, CD79A
48beriberi10.5CD40LG, CD79A
49choroid plexus meningioma10.5CD40LG, CD79A
50immunotactoid glomerulopathy10.5CD40LG, CD79A

Graphical network of the top 20 diseases related to Adenoiditis:



Diseases related to adenoiditis

Symptoms for Adenoiditis

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Symptoms:

 10
  • pain
  • redness
  • swelling
  • difficulty swallowing

Drugs & Therapeutics for Adenoiditis

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Drugs for Adenoiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DexmedetomidineapprovedPhase 4470113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
2Hypnotics and SedativesPhase 42032
3Neurotransmitter AgentsPhase 414795
4Peripheral Nervous System AgentsPhase 418510
5Central Nervous System DepressantsPhase 410016
6Analgesics, Non-NarcoticPhase 45184
7Adrenergic AgonistsPhase 42331
8Adrenergic alpha-2 Receptor AgonistsPhase 4790
9Adrenergic alpha-AgonistsPhase 41300
10AnalgesicsPhase 49358
11Adrenergic AgentsPhase 44204

Interventional clinical trials:

idNameStatusNCT IDPhase
1The Effect of Dexmedetomidine on Airway Complications After Deep or Awake ExtubationRecruitingNCT02162433Phase 4

Search NIH Clinical Center for Adenoiditis

Genetic Tests for Adenoiditis

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Anatomical Context for Adenoiditis

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MalaCards organs/tissues related to Adenoiditis:

33
Endothelial, Breast, Bone, T cells, Lung, Liver, Brain

Animal Models for Adenoiditis or affiliated genes

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MGI Mouse Phenotypes related to Adenoiditis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.1BCL10, CD40LG, FKBP4, GNAS, SRC, SYK
2MP:00053846.7BCL10, CD40LG, CD69, CD79A, FKBP4, GNAS
3MP:00053906.7CD40LG, CD68, CD69, GNAS, RING1, SRC
4MP:00053874.8BCL10, CARD9, CD40LG, CD68, CD69, CD79A
5MP:00053974.6BCL10, CARD9, CD40LG, CD68, CD69, CD79A

Publications for Adenoiditis

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Articles related to Adenoiditis:

(show top 50)    (show all 905)
idTitleAuthorsYear
1
Microcystic Stromal Tumor: A Distinctive Ovarian Sex Cord-Stromal Neoplasm Characterized by FOXL2, SF-1, WT-1, Cyclin D1, and I^-catenin Nuclear Expression and CTNNB1 Mutations. (26200099)
2015
2
Synthesis and biological evaluation of nitric oxide-donating analogues of sulindac for prostate cancer treatment. (24387865)
2014
3
The antigenic switching network of Plasmodium falciparum and its implications for the immuno-epidemiology of malaria. (24062941)
2013
4
Projected Cost Comparison of Trabectome, iStent, and Endoscopic Cyclophotocoagulation Versus Glaucoma Medication in the Ontario Health Insurance Plan. (23807348)
2013
5
Sectoral loss of myelin and axons in anterior ischemic optic neuropathy. (23528450)
2013
6
Assessment of the response of patients with Crohn's disease to biological therapy using new non-invasive markers: lactoferrin and calprotectin. (23903623)
2013
7
Are nasopharyngeal cultures useful in diagnosis of acute bacterial sinusitis in children? (24137025)
2013
8
Calcium binding to leptospira outer membrane antigen LipL32 is not necessary for its interaction with plasma fibronectin, collagen type IV, and plasminogen. (22147698)
2012
9
Management of ocular sarcoidosis. (23311120)
2012
10
Pathogenesis of bronchiectasis. (22640841)
2012
11
A comparative search for human FcI/RII+ gene (FCER1A) 3'-UTR polymorphisms in Japanese and Polish populations. (21725845)
2012
12
Molecular and genetic evidence for abnormalities in the nodes of Ranvier in schizophrenia. (21893642)
2012
13
Copy number variation in patients with disorders of sex development due to 46,XY gonadal dysgenesis. (21408189)
2011
14
Chilaiditi syndrome and associated caecal volvulus. (22295356)
2011
15
Hypertrophic cardiomyopathy: from genetics to treatment. (20503496)
2010
16
Interaction of intestinal and pancreatic transcription factors in the regulation of CFTR gene expression. (19782160)
2009
17
Structure of the sulphiredoxin-peroxiredoxin complex reveals an essential repair embrace. (18172504)
2008
18
Chronic actinic dermatitis. (18627761)
2008
19
Regression of white matter MRI abnormalities in nonvasculitic autoimmune inflammatory meningoencephalitis following intravenous immunoglobulin. (17389804)
2007
20
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (17043677)
2007
21
Purification, crystallization and preliminary X-ray diffraction study of human ribosomal protein L10 core domain. (18007048)
2007
22
Microtubules: an overview. (18085218)
2007
23
PACAP support of neuronal survival requires MAPK- and activity-generated signals. (16431129)
2006
24
Management of amiodarone-induced thyrotoxicosis in Latin America: an electronic survey. (16984234)
2006
25
Endotoxin evaluation of eleven lipopolysaccharides by whole blood assay does not always correlate with Limulus amebocyte lysate assay. (16719988)
2006
26
Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization. (16634642)
2006
27
The influence of estrogen on migraine: a systematic review. (16622144)
2006
28
Elephantiasis Nostras Verrucosa: a rare thyroid dermopathy in Graves' disease. (16121817)
2005
29
A novel GALNT3 mutation in a pseudoautosomal dominant form of tumoral calcinosis: evidence that the disorder is autosomal recessive. (15687324)
2005
30
Soft tissue sacrococcygeal chordoma with intracytoplasmic filamentous inclusions. (16325512)
2005
31
Curcumin suppresses growth and induces apoptosis in primary effusion lymphoma. (16044161)
2005
32
Non-fusion expression in Escherichia coli, purification, and characterization of a novel Ca2+- and phospholipid-binding protein annexin B1. (14766301)
2004
33
Serotonin-1D hypothesis of obsessive-compulsive disorder: an update. (15554784)
2004
34
Cataract in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD). (12660866)
2003
35
The value of pituitary magnetic resonance imaging in men with hypogonadism. (12913700)
2003
36
Transforming growth factor-beta induces secretion of activated ADAMTS-2. A procollagen III N-proteinase. (12646579)
2003
37
Phencyclidine increases vesicular dopamine uptake. (11906713)
2002
38
Decreased levels of CXCR3 transcripts in peripheral blood mononuclear cells from patients with atopic dermatitis and with cutaneous diseases associated with eosinophilia. (11480592)
2001
39
Changes in systemic levels of insulin-like growth factors and their binding proteins in patients with rheumatoid arthritis. (11247331)
2001
40
Hyperplasia of type II pneumocytes in pulmonary lymphangioleiomyomatosis. (11079017)
2000
41
Structure/function studies of glycosyltransferases. (10508766)
1999
42
Structural organization and splice variants of the POLE1 gene encoding the catalytic subunit of human DNA polymerase epsilon. (10215605)
1999
43
Prenatal plasma matrix metalloproteinase-9 levels to predict spontaneous preterm birth. (9721787)
1998
44
Mutations of the alpha2(V) chain of type V collagen impair matrix assembly and produce Ehlers-Danlos syndrome type I. (9425231)
1998
45
Detection of serum antibodies to Chlamydia pneumoniae in patients with endogenous uveitis and acute conjunctivitis. (9356816)
1997
46
Metarhodopsin III formation and decay kinetics: comparison of bovine and human rhodopsin. (9068826)
1997
47
Purine deoxynucleoside metabolism in human melanoma cells with a high spontaneous mutation rate. (8657185)
1996
48
Interferon alpha and etretinate combination treatment of cutaneous T-cell lymphoma. (2258637)
1990
49
Neonatal thyrotoxicosis treated with exchange transfusion and Lugol's iodine. (2859196)
1985
50

Variations for Adenoiditis

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Expression for genes affiliated with Adenoiditis

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Search GEO for disease gene expression data for Adenoiditis.

Pathways for genes affiliated with Adenoiditis

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Pathways related to Adenoiditis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.8SRC, SYK
2
Show member pathways
9.4BCL10, CD40LG, MALT1, SYK
39.4BCL10, CD40LG, MALT1, SYK
4
Show member pathways
9.1BCL10, CD40LG, MALT1, SYK
5
Show member pathways
8.9BCL10, CARD9, CD209, MALT1, SRC, SYK
68.9BCL10, CARD9, CD209, MALT1, SRC, SYK
7
Show member pathways
8.9BCL10, CARD9, CD209, MALT1, SRC, SYK
88.7CD209, CD68, CD69, CD79A
9
Show member pathways
8.1BCL10, CD79A, GNAS, MALT1, SRC, SYK
10
Show member pathways
7.1BCL10, CARD9, CD209, CD40LG, CD79A, HAVCR2

GO Terms for genes affiliated with Adenoiditis

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Biological processes related to Adenoiditis according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of innate immune responseGO:004508910.6CARD9, HAVCR2
2macrophage activation involved in immune responseGO:000228110.6HAVCR2, SYK
3leukocyte cell-cell adhesionGO:000715910.4CD40LG, SYK
4positive regulation of cytokine secretionGO:005071510.4SRC, SYK
5integrin-mediated signaling pathwayGO:000722910.1SRC, SYK, TYROBP
6stimulatory C-type lectin receptor signaling pathwayGO:000222310.0CARD9, SRC, SYK
7intracellular signal transductionGO:00355569.9CD209, SRC, SYK, TYROBP
8regulation of immune responseGO:00507769.8CD40LG, TREM1, TYROBP
9adaptive immune responseGO:00022509.6BCL10, CD209, CD79A, HAVCR2, SYK
10positive regulation of NF-kappaB transcription factor activityGO:00510929.6BCL10, CD40LG, LTF, MALT1
11cellular response to lipopolysaccharideGO:00712229.3HAVCR2, SRC, TSPO
12innate immune responseGO:00450878.5CARD9, CD209, HAVCR2, SRC, SYK, TREM1

Sources for Adenoiditis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet