Aliases & Classifications for Adenoiditis

Aliases & Descriptions for Adenoiditis:

Name: Adenoiditis 12 14 69
Chronic Adenoiditis 12 69

Classifications:



External Ids:

Disease Ontology 12 DOID:0050145
ICD10 33 J35.02
ICD9CM 35 474.01
SNOMED-CT 64 195794009 232420002
UMLS 69 C0396023

Summaries for Adenoiditis

Disease Ontology : 12 An upper respiratory tract disease which involves inflammation, pain, and swelling of the adenoid tissue due to the infection by bacteria and viruses. It occurs primarily in children and may be secondary to an allergy, infection of nose or throat and an obstruction of the eustachian tube. The infection has symptom pain, has symptom redness, has symptom swelling, and has symptom difficulty swallowing.

MalaCards based summary : Adenoiditis, also known as chronic adenoiditis, is related to adenoid hypertrophy and salivary gland adenoid cystic carcinoma, and has symptoms including pain, redness and swelling. An important gene associated with Adenoiditis is FCN2 (Ficolin 2), and among its related pathways/superpathways is Tuberculosis. The drugs Dexmedetomidine and Analgesics have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, breast and lung, and related phenotypes are Increased shRNA abundance (Z-score > 2) and hematopoietic system

Wikipedia : 71 Adenoiditis is the inflammation of the adenoid tissue, usually caused by an infection. Adenoiditis is... more...

Related Diseases for Adenoiditis

Diseases related to Adenoiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 161)
id Related Disease Score Top Affiliating Genes
1 adenoid hypertrophy 12.3
2 salivary gland adenoid cystic carcinoma 12.2
3 cervical adenoid cystic carcinoma 11.9
4 maxillary sinus adenoid cystic carcinoma 11.9
5 lacrimal gland adenoid cystic carcinoma 11.9
6 adenoid basal cell carcinoma 11.9
7 breast adenoid cystic carcinoma 11.9
8 esophageal adenoid cystic carcinoma 11.9
9 laryngeal adenoid cystic carcinoma 11.9
10 bartholin's gland adenoid cystic carcinoma 11.9
11 adenoid squamous cell carcinoma 11.9
12 prostate adenoid cystic carcinoma 11.8
13 lung adenoid cystic carcinoma 11.8
14 trachea adenoid cystic carcinoma 11.8
15 ethmoid sinus adenoid cystic carcinoma 11.8
16 adenoid basal carcinoma of the cervix uteri 11.7
17 parotid gland adenoid cystic carcinoma 11.7
18 lymph node adenoid cystic carcinoma 11.7
19 adenoid cystic carcinoma of the corpus uteri 11.7
20 cervical adenoid basal carcinoma 11.7
21 sublingual gland adenoid cystic carcinoma 11.6
22 tonsillitis 11.5
23 multiple familial trichoepithelioma 11.4
24 trichoepithelioma, multiple familial, 1 11.3
25 sleep apnea 11.1
26 paranasal sinus cancer 11.0
27 cutaneous adenocystic carcinoma 11.0
28 prostate cancer, hereditary, 2 10.7
29 prostate cancer, hereditary, 11 10.7
30 prostate cancer 1 10.7
31 plague 10.7
32 prostate cancer 10.7
33 prostate cancer, hereditary, 12 10.7
34 calcifying epithelial odontogenic tumor 10.7
35 prostate cancer, hereditary, 13 10.7
36 ceruminous carcinoma 10.7
37 squamous cell carcinoma 10.3
38 adenocarcinoma 10.2
39 polymorphous low-grade adenocarcinoma 10.2
40 otitis media 10.2
41 adenoma 10.2
42 pleomorphic adenoma 10.1
43 basal cell carcinoma 10.1
44 chronic conjunctivitis 10.0
45 mucoepidermoid carcinoma 10.0
46 endotheliitis 9.9
47 nasopharyngitis 9.9
48 laryngitis 9.9
49 cervicitis 9.9
50 sinusitis 9.9

Graphical network of the top 20 diseases related to Adenoiditis:



Diseases related to Adenoiditis

Symptoms & Phenotypes for Adenoiditis

Symptoms:

12
  • pain
  • redness
  • swelling
  • difficulty swallowing

GenomeRNAi Phenotypes related to Adenoiditis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.4 LY75
2 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.4 TYROBP
3 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.4 LY75
4 Increased shRNA abundance (Z-score > 2) GR00366-A-110 9.4 LY75
5 Increased shRNA abundance (Z-score > 2) GR00366-A-129 9.4 TYROBP LY75
6 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.4 LY75
7 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.4 LY75
8 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.4 TYROBP
9 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.4 TYROBP
10 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.4 LY75
11 Increased shRNA abundance (Z-score > 2) GR00366-A-93 9.4 LY75

MGI Mouse Phenotypes related to Adenoiditis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.35 CARD9 CLEC7A CNOT4 LY75 TYROBP
2 immune system MP:0005387 9.02 CARD9 CLEC7A CNOT4 LY75 TYROBP

Drugs & Therapeutics for Adenoiditis

Drugs for Adenoiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
2 Analgesics Phase 4
3 Adrenergic Agents Phase 4
4 Adrenergic Agonists Phase 4
5 Adrenergic alpha-2 Receptor Agonists Phase 4
6 Adrenergic alpha-Agonists Phase 4
7 Neurotransmitter Agents Phase 4
8 Analgesics, Non-Narcotic Phase 4
9 Peripheral Nervous System Agents Phase 4
10 Pharmaceutical Solutions Phase 4
11 Hypnotics and Sedatives Phase 4
12 Central Nervous System Depressants Phase 4

Interventional clinical trials:


id Name Status NCT ID Phase
1 The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation Recruiting NCT02162433 Phase 4

Search NIH Clinical Center for Adenoiditis

Genetic Tests for Adenoiditis

Anatomical Context for Adenoiditis

MalaCards organs/tissues related to Adenoiditis:

39
Salivary Gland, Breast, Lung, Tonsil, Trachea, Skin, Tongue

Publications for Adenoiditis

Articles related to Adenoiditis:

(show top 50) (show all 1008)
id Title Authors Year
1
c-Myb Overexpression in Cytology Smears of Tracheobronchial and Pulmonary Adenoid Cystic Carcinomas. ( 27974718 )
2017
2
Downregulation of miR-222 Induces Apoptosis and Cellular Migration in Adenoid Cystic Carcinoma Cells. ( 28277192 )
2017
3
HIF1I+ in Tumorigenesis of Adenoid Cystic Carcinoma. ( 28179306 )
2017
4
Intra-arterial Chemotherapy for Lacrimal Gland Adenoid Cystic Carcinoma. ( 27898620 )
2017
5
The unique luminal staining pattern of cytokeratin 5/6 in adenoid cystic carcinoma of the breast may aid in differentiating it from its mimickers. ( 27240462 )
2016
6
Expression of SKA1 and MMP-9 in primary salivary adenoid cystic carcinoma: Correlation with tumor progression and patient prognosis. ( 26881872 )
2016
7
Application of p16 Immunohistochemistry and RNA In Situ Hybridization in the Classification of Adenoid Basal Tumors of the Cervix. ( 26352551 )
2016
8
PRL-3 promotes migration and invasion and is associated with poor prognosis in salivary adenoid cystic carcinoma. ( 26041460 )
2016
9
Re-affirming the necessity of sending even minor surgical specimens for histopathology: a case of inverted papilloma of the adenoids. ( 27685930 )
2016
10
FCN2 c.772G>T polymorphism is associated with chronic adenoiditis and/or tonsillitis, but notA -4 A>G andA -602A G>A. ( 27368434 )
2016
11
Myoepithelial differentiation in cribriform, tubular and solid pattern of adenoid cystic carcinoma: A potential involvement in histological grading and prognosis. ( 27180054 )
2016
12
MYB expression: Potential role in separating adenoid cystic carcinoma (ACC) from pleomorphic adenoma (PA). ( 27491495 )
2016
13
Adenoid cystic carcinoma presenting as an orbital apex mass with intracranial extension. ( 27085282 )
2016
14
Does adenoid hypertrophy affect disease severity in children with allergic rhinitis? ( 27405740 )
2016
15
Adenoid Cystic Carcinoma of Trachea: A Diagnostic and Therapeutic Challenge. ( 27066420 )
2016
16
Association between clinical features, treatment, and recurrence rate of adenoid cystic carcinoma of the palate: a 10-year retrospective study. ( 27094499 )
2016
17
Laryngeal Adenoid Cystic Carcinoma: A Systematic Review. ( 26701176 )
2016
18
Clinical utility of myb rearrangement detection and p63/p40 immunophenotyping in the diagnosis of adenoid cystic carcinoma of minor salivary glands: a pilot study. ( 26711711 )
2016
19
Differing Lymphatic Vessels Density in Salivary Adenoid Cystic Carcinoma and Pleomorphic Adenoma. ( 27837476 )
2016
20
Downregulation of nucleophosmin expression inhibited proliferation and induced apoptosis in salivary gland adenoid cystic carcinoma. ( 27501253 )
2016
21
Adenoid hypertrophy and chronic rhinosinusitis: Helicobacter pylori on antral lavages, adenoid tissue and salival inmunoglobuline A on paediatric patients. ( 26746618 )
2016
22
EphA2 silencing promotes growth, migration, and metastasis in salivary adenoid cystic carcinoma: in vitro and in vivo study. ( 27186278 )
2016
23
Bmi-1 expression predicts prognosis in salivary adenoid cystic carcinoma and correlates with epithelial-mesenchymal transition-related factors. ( 27180058 )
2016
24
Carcinoma-Associated Fibroblasts Lead the Invasion of Salivary Gland Adenoid Cystic Carcinoma Cells by Creating an Invasive Track. ( 26954362 )
2016
25
Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma. ( 26862087 )
2016
26
SOD2 deregulation enhances migration, invasion and has poor prognosis in salivary adenoid cystic carcinoma. ( 27181103 )
2016
27
Adenoid basal cell carcinoma: a rare facet of basal cell carcinoma. ( 27095806 )
2016
28
MicroRNA-144-3p inhibits proliferation and induces apoptosis of human salivary adenoid carcinoma cells via targeting of mTOR. ( 26687302 )
2016
29
Definitive Radiotherapy for Skin and Adenoid Cystic Carcinoma with Perineural Invasion. ( 27123393 )
2016
30
The common genetic variants of toll-like receptor and susceptibilityto adenoid hypertrophy: a hospital-based cohort study. ( 27966312 )
2016
31
Expression of Submaxillary Gland Androgen-regulated Protein 3A (SMR3A) in Adenoid Cystic Carcinoma of the Head and Neck. ( 26851015 )
2016
32
The effect of adenoid hypertrophy on maxillofacial development: an objective photographic analysis. ( 27647047 )
2016
33
1,25-Dihydroxyvitamin D3 alleviates salivary adenoid cystic carcinoma progression by suppressing GPX1 expression through the NF-I_B pathway. ( 26782341 )
2016
34
Well-differentiated fetal adenocarcinoma of the lung mimicking adenoid cystic carcinoma on fine needle aspiration: A case report. ( 27374425 )
2016
35
Primary Mediastinal Synovial Sarcoma with subsequent development of Primary Adenoid Cystic Carcinoma of Lung presenting as superior vena cava syndrome. ( 26992072 )
2016
36
Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review. ( 27084720 )
2016
37
Expression of Autophagy and Reactive Oxygen Species-Related Proteins in Lacrimal Gland Adenoid Cystic Carcinoma. ( 26847304 )
2016
38
Accuracy and reliability of orthodontists using cone-beam computerized tomography for assessment of adenoid hypertrophy. ( 27871704 )
2016
39
Inhibitory effects of silibinin on proliferation and lung metastasis of human high metastasis cell line of salivary gland adenoid cystic carcinoma via autophagy induction. ( 27822066 )
2016
40
Type III TGF-I^ receptor inhibits cell proliferation and migration in salivary glands adenoid cystic carcinoma by suppressing NF-I_B signaling. ( 26531330 )
2016
41
Nonencapsulated Streptococcus pneumoniae as a cause of chronic adenoiditis. ( 27144125 )
2016
42
The effect of adenoid hypertrophy and adenoidectomy in patients on cardiovascular risk reduction. ( 27405084 )
2016
43
Adding concurrent chemotherapy to postoperative radiotherapy improves locoregional control but Not overall survival in patients with salivary gland adenoid cystic carcinoma-a propensity score matched study. ( 27000157 )
2016
44
Sporadic Burkitt Lymphoma Presenting as Acute Pancreatitis, Concurrent Sinusitis, and Enlarged Adenoids. ( 27213067 )
2016
45
Fine-Needle Aspiration of Epithelial-Myoepithelial Carcinoma of the Parotid Gland With Prominent Adenoid Cystic Carcinoma-Like Cribriform Features: Avoiding a Diagnostic Pitfall. ( 27614667 )
2016
46
Twist Expression in Pleomorphic Adenoma, Adenoid Cystic Carcinoma and Mucoepidermoid Carcinoma of Salivary Glands. ( 26832177 )
2016
47
In Vivo Visualization of Prostate-Specific Membrane Antigen in Adenoid Cystic Carcinoma of the Salivary Gland. ( 27055136 )
2016
48
Adenoid Cystic Carcinoma of the Trachea. ( 27065684 )
2016
49
Tympanometric Findings among Children with Adenoid Hypertrophy in Port Harcourt, Nigeria. ( 27563311 )
2016
50
Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screening. ( 27212063 )
2016

Variations for Adenoiditis

Expression for Adenoiditis

Search GEO for disease gene expression data for Adenoiditis.

Pathways for Adenoiditis

Pathways related to Adenoiditis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.88 CARD9 CLEC7A

GO Terms for Adenoiditis

Biological processes related to Adenoiditis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.33 CARD9 CLEC7A FCN2
2 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.26 CARD9 CLEC7A
3 defense response to Gram-positive bacterium GO:0050830 8.96 CARD9 FCN2
4 innate immune response GO:0045087 8.92 CARD9 CLEC7A FCN2 TYROBP

Molecular functions related to Adenoiditis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 carbohydrate binding GO:0030246 8.8 CLEC7A FCN2 LY75

Sources for Adenoiditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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