Aliases & Classifications for Adenoiditis

About this section

Aliases & Descriptions for Adenoiditis:

Name: Adenoiditis 10 12 65
 
Chronic Adenoiditis 10 65

Classifications:



External Ids:

Disease Ontology10 DOID:0050145
ICD1027 J35.02
ICD9CM29 474.01
UMLS65 C0396023, C0001427

Summaries for Adenoiditis

About this section
Disease Ontology:10 An upper respiratory tract disease which involves inflammation, pain, and swelling of the adenoid tissue due to the infection by bacteria and viruses. It occurs primarily in children and may be secondary to an allergy, infection of nose or throat and an obstruction of the eustachian tube. The infection has symptom pain, has symptom redness, has symptom swelling, and has symptom difficulty swallowing.

MalaCards based summary: Adenoiditis, also known as chronic adenoiditis, is related to chronic conjunctivitis and sialadenitis, and has symptoms including pain, redness and swelling. An important gene associated with Adenoiditis is CARD9 (Caspase Recruitment Domain Family Member 9), and among its related pathways are Atypical NF-kappaB pathway and ICos-ICosL Pathway in T-Helper Cell. Affiliated tissues include salivary gland, breast and prostate, and related mouse phenotypes are endocrine/exocrine gland and cellular.

Wikipedia:68 Adenoiditis is the inflammation of the adenoid tissue, usually caused by an infection. Adenoiditis is... more...

Related Diseases for Adenoiditis

About this section

Diseases related to Adenoiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 221)
idRelated DiseaseScoreTop Affiliating Genes
1chronic conjunctivitis31.0CD79A, LTF, TSPO
2sialadenitis30.4CD40LG, CD79A
3adenoid hypertrophy12.3
4salivary gland adenoid cystic carcinoma12.3
5cervical adenoid cystic carcinoma12.1
6maxillary sinus adenoid cystic carcinoma12.0
7lacrimal gland adenoid cystic carcinoma12.0
8adenoid basal cell carcinoma12.0
9breast adenoid cystic carcinoma12.0
10esophageal adenoid cystic carcinoma12.0
11laryngeal adenoid cystic carcinoma12.0
12bartholin's gland adenoid cystic carcinoma12.0
13adenoid squamous cell carcinoma12.0
14prostate adenoid cystic carcinoma11.9
15lung adenoid cystic carcinoma11.9
16trachea adenoid cystic carcinoma11.9
17ethmoid sinus adenoid cystic carcinoma11.9
18adenoid basal carcinoma of the cervix uteri11.9
19parotid gland adenoid cystic carcinoma11.8
20lymph node adenoid cystic carcinoma11.8
21cervical adenoid basal carcinoma11.8
22adenoid cystic carcinoma of the corpus uteri11.8
23sublingual gland adenoid cystic carcinoma11.8
24multiple familial trichoepithelioma11.3
25trichoepithelioma, multiple familial, 111.2
26paranasal sinus cancer11.1
27cutaneous adenocystic carcinoma11.1
28primary cutaneous gamma/delta-positive t-cell lymphoma10.8BCL10, MALT1
29meckel's diverticulum10.8CD79A, LTF
30bard1-related susceptibility to breast cancer10.8BCL10, MALT1
31tonsillitis10.8
32typhus10.8CD40LG, CD79A
33pulmonary edema10.8CD40LG, CD79A
34congenital hypogammaglobulinemia10.7CD40LG, CD79A
35calabro syndrome10.7CD40LG, CD79A
36gamma heavy chain disease10.7CD40LG, CD79A
37exanthema subitum10.7CD40LG, CD79A
38osteomalacia10.7CD40LG, CD79A
39epidermolysis bullosa simplex10.7CD40LG, CD79A
40proliferative glomerulonephritis10.7CD40LG, CD79A
41cryopyrin-associated periodic syndrome10.7CD40LG, CD79A
42acute salpingitis10.7CD40LG, CD79A
43beriberi10.7CD40LG, CD79A
44cystitis10.7CD40LG, CD79A
45purpura10.7CD40LG, CD79A
46choroid plexus meningioma10.7CD40LG, CD79A
47immunotactoid glomerulopathy10.7CD40LG, CD79A
48erdheim-chester disease10.7CD209, CD40LG
49subacute delirium10.7CD40LG, CD79A
50acute diarrhea10.7CARD9, SYK

Graphical network of the top 20 diseases related to Adenoiditis:



Diseases related to adenoiditis

Symptoms for Adenoiditis

About this section

Symptoms:

 10
  • pain
  • redness
  • swelling
  • difficulty swallowing

UMLS symptoms related to Adenoiditis:


pain of lymph node

Drugs & Therapeutics for Adenoiditis

About this section

Drugs for Adenoiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DexmedetomidineapprovedPhase 4470113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
2Hypnotics and SedativesPhase 42032
3Neurotransmitter AgentsPhase 414795
4Peripheral Nervous System AgentsPhase 418510
5Central Nervous System DepressantsPhase 410016
6Analgesics, Non-NarcoticPhase 45184
7Adrenergic AgonistsPhase 42331
8Adrenergic alpha-2 Receptor AgonistsPhase 4790
9Adrenergic alpha-AgonistsPhase 41300
10AnalgesicsPhase 49358
11Adrenergic AgentsPhase 44204

Interventional clinical trials:

idNameStatusNCT IDPhase
1The Effect of Dexmedetomidine on Airway Complications After Deep or Awake ExtubationRecruitingNCT02162433Phase 4

Search NIH Clinical Center for Adenoiditis

Genetic Tests for Adenoiditis

About this section

Anatomical Context for Adenoiditis

About this section

MalaCards organs/tissues related to Adenoiditis:

33
Salivary gland, Breast, Prostate, Lung, Tonsil, B cells, Trachea

Animal Models for Adenoiditis or affiliated genes

About this section

MGI Mouse Phenotypes related to Adenoiditis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.1BCL10, CD40LG, FKBP4, GNAS, SRC, SYK
2MP:00053846.7BCL10, CD40LG, CD69, CD79A, FKBP4, GNAS
3MP:00053906.7CD40LG, CD68, CD69, GNAS, RING1, SRC
4MP:00053874.8BCL10, CARD9, CD40LG, CD68, CD69, CD79A
5MP:00053974.6BCL10, CARD9, CD40LG, CD68, CD69, CD79A

Publications for Adenoiditis

About this section

Articles related to Adenoiditis:

(show top 50)    (show all 936)
idTitleAuthorsYear
1
miR-21 regulates tumor progression through the miR-21-PDCD4-Stat3 pathway in human salivary adenoid cystic carcinoma. (26367487)
2015
2
C-kit induces epithelial-mesenchymal transition and contributes to salivary adenoid cystic cancer progression. (24721839)
2014
3
CXCR4 antagonist inhibits perineural invasion of adenoid cystic carcinoma. (25118295)
2014
4
RASSF1A promoter hypermethylation is a strong biomarker of poor survival in patients with salivary adenoid cystic carcinoma in a Chinese population. (25302792)
2014
5
Induction of autophagy-dependent cell death by the survivin suppressant YM155 in salivary adenoid cystic carcinoma. (24370995)
2013
6
Adenoid cystic carcinoma in the bronchus behaves more aggressively than its tracheal counterpart. (24094522)
2013
7
Adenoid cystic carcinoma of palate: A case report and review of literature. (23946749)
2013
8
High grade transformation in a case of adenoid cystic carcinoma associated with Epstein-Barr virus expression. (24247629)
2013
9
Immunohistochemical clue for the histological overlap of salivary adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma. (24265903)
2013
10
Analysis of failure in patients with adenoid cystic carcinoma of the head and neck. An international collaborative study. (23784851)
2013
11
EMMPRIN contributes to the in vitro invasion of human salivary adenoid cystic carcinoma cells. (22200897)
2012
12
Molecular biology of adenoid cystic carcinoma. (22006498)
2012
13
Differential expression of aquaporin 5 and aquaporin 3 in squamous cell carcinoma and adenoid cystic carcinoma. (22576684)
2012
14
Adenoid cystic carcinoma of the airway: a 30-year review at one institution. (21907453)
2012
15
Dysphagia due to adenoid cystic carcinoma of the base of the tongue. (22737963)
2012
16
A primary cutaneous adenoid-cystic carcinoma in a young woman. Differential diagnosis and clinical implications. (21464876)
2011
17
Dedifferentiated adenoid cystic carcinoma of the lacrimal gland. (21283029)
2011
18
Adenoid cystic carcinoma of the base of the tongue: Late metastasis to the pancreas. (22096672)
2011
19
Prognostic value of quantitative p63 immunostaining in adenoid cystic carcinoma of salivary gland assessed by computerized image analysis. (19877114)
2010
20
Prognostic significance of nuclear survivin expression in resected adenoid cystic carcinoma of the head and neck. (21034499)
2010
21
Adjuvant radiation therapy is associated with improved survival for adenoid cystic carcinoma of the breast. (20589709)
2010
22
Primary cutaneous adenoid cystic carcinoma in the United States: incidence, survival, and associated cancers, 1976 to 2005. (20447723)
2010
23
Expression of p-AKT characterizes adenoid cystic carcinomas of head and neck with a higher risk for tumor relapses. (19545368)
2009
24
Metastasectomy for hepatic metastases from adenoid cystic carcinoma of the trachea. (20431735)
2009
25
The development of primary cutaneous adenoid cystic carcinoma in a patient with ankylosing spondylitis treated with etanercept. (19488017)
2009
26
Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. (19031084)
2009
27
Effects of basic fibroblast growth factor on the proliferation of human salivary adenoid cystic carcinoma cell line ACC-2 and extracellular signal-regulated kinase, Cyclin D1, p2waf/cip1 signaling pathway]. (18605443)
2008
28
Adenoid cystic carcinoma of trachea treated with adjuvant hypofractionated tomotherapy. Case report and literature review. (18468347)
2008
29
Adenoid cystic/basal cell carcinoma of the prostate. (18295260)
2008
30
High expression of Polycomb group protein EZH2 predicts poor survival in salivary gland adenoid cystic carcinoma. (18326020)
2008
31
The selective expression of CD43 in adenoid cystic carcinoma. (18227725)
2008
32
Papillary adenoid hyperplasia in focal dermal hypoplasia. (18503862)
2008
33
Expression of neural cell adhesion molecule in salivary adenoid cystic carcinoma and its correlation with perineural invasion. (17982624)
2007
34
A phase II study of Imatinib for advanced adenoid cystic carcinoma of head and neck salivary glands. (16757202)
2007
35
Cytodiagnosis of adenoid cystic carcinoma of the breast. (17883166)
2007
36
Unresectable adenoid cystic carcinoma of the trachea treated with chemoradiation. (18048830)
2007
37
Toll-like receptor expression in the human nasopharyngeal tonsil (adenoid) and palantine tonsils: a preliminary report. (16325925)
2006
38
Tracheobronchial adenoid cystic carcinoma: a clinicopathologic study of 14 cases. (15006985)
2004
39
Differential expression of basement membrane type-IV collagen alpha1, alpha2, alpha5 and alpha6 chains among the histological subtypes of adenoid cystic carcinoma. (15138813)
2004
40
Adenoid cystic carcinoma with hyperostosis after stereotactic radiosurgery. (15287538)
2004
41
Assessment of p63 expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and basal cell and canalicular adenomas. (15153875)
2004
42
Urokinase-type plasminogen activator receptor expression in adenoid cystic carcinoma of the skull base. (12578452)
2003
43
A case of adenoid cystic carcinoma (ACC) of the breast and review of the utility of preoperative imaging diagnose. (11180772)
2001
44
Effect of amoxycillin with or without clavulanate on adenoid bacterial flora. (11481299)
2001
45
Detection of neuroendocrine feature about salivary adenoid cystic carcinoma]. (12539703)
1999
46
Oral adenoid squamous cell carcinoma: a report of three cases and review of the literature. (8492207)
1993
47
Expressions of oncogene products in adenoid cystic carcinomas of salivary glands: immunohistochemical study]. (1665502)
1991
48
Adenoid basal cell carcinoma of the vulva. (7185765)
1982
49
Multiple adenoid squamous cell carcinoma. (5093173)
1971
50

Variations for Adenoiditis

About this section

Expression for genes affiliated with Adenoiditis

About this section
Search GEO for disease gene expression data for Adenoiditis.

Pathways for genes affiliated with Adenoiditis

About this section

Pathways related to Adenoiditis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.8SRC, SYK
2
Show member pathways
9.4BCL10, CD40LG, MALT1, SYK
39.4BCL10, CD40LG, MALT1, SYK
4
Show member pathways
9.1BCL10, CD40LG, CD79A, MALT1, SYK
5
Show member pathways
8.9BCL10, CARD9, CD209, MALT1, SRC, SYK
68.9BCL10, CARD9, CD209, MALT1, SRC, SYK
7
Show member pathways
8.9BCL10, CARD9, CD209, MALT1, SRC, SYK
88.7CD209, CD68, CD69, CD79A
9
Show member pathways
8.1BCL10, CD79A, GNAS, MALT1, SRC, SYK
10
Show member pathways
7.1BCL10, CARD9, CD209, CD40LG, CD79A, HAVCR2

GO Terms for genes affiliated with Adenoiditis

About this section

Biological processes related to Adenoiditis according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of innate immune responseGO:004508910.6CARD9, HAVCR2
2macrophage activation involved in immune responseGO:000228110.6HAVCR2, SYK
3leukocyte cell-cell adhesionGO:000715910.4CD40LG, SYK
4positive regulation of cytokine secretionGO:005071510.4SRC, SYK
5integrin-mediated signaling pathwayGO:000722910.1SRC, SYK, TYROBP
6stimulatory C-type lectin receptor signaling pathwayGO:000222310.0CARD9, SRC, SYK
7intracellular signal transductionGO:00355569.9CD209, SRC, SYK, TYROBP
8regulation of immune responseGO:00507769.8CD40LG, TREM1, TYROBP
9adaptive immune responseGO:00022509.6BCL10, CD209, CD79A, HAVCR2, SYK
10positive regulation of NF-kappaB transcription factor activityGO:00510929.6BCL10, CD40LG, LTF, MALT1
11cellular response to lipopolysaccharideGO:00712229.3HAVCR2, SRC, TSPO
12innate immune responseGO:00450878.5CARD9, CD209, HAVCR2, SRC, SYK, TREM1

Sources for Adenoiditis

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet