Aliases & Classifications for Adenoiditis

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Aliases & Descriptions for Adenoiditis:

Name: Adenoiditis 10 12 65
 
Chronic Adenoiditis 10 65


Classifications:



External Ids:

Disease Ontology10 DOID:0050145
ICD9CM29 474.01

Summaries for Adenoiditis

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Disease Ontology:10 An upper respiratory tract disease which involves inflammation, pain, and swelling of the adenoid tissue due to the infection by bacteria and viruses. it occurs primarily in children and may be secondary to an allergy, infection of nose or throat and an obstruction of the eustachian tube. the infection has symptom pain, has symptom redness, has symptom swelling, and has symptom difficulty swallowing.

MalaCards based summary: Adenoiditis, also known as chronic adenoiditis, is related to nasopharyngitis and atopic dermatitis, and has symptoms including pain, redness and swelling. An important gene associated with Adenoiditis is CARD9 (Caspase Recruitment Domain Family, Member 9), and among its related pathways are Atypical NF-kappaB pathway and ICos-ICosL Pathway in T-Helper Cell. Affiliated tissues include salivary gland, breast and tonsil, and related mouse phenotypes are skeleton and hematopoietic system.

Wikipedia:68 Adenoiditis is the inflammation of the adenoid tissue, usually caused by an infection. Adenoiditis is... more...

Related Diseases for Adenoiditis

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Diseases related to Adenoiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 264)
idRelated DiseaseScoreTop Affiliating Genes
1nasopharyngitis30.6CD40LG, CD79A, FKBP4
2atopic dermatitis30.3CD40LG, CD79A
3sarcoma30.3CD40LG, CD79A
4hyperostosis30.2CD40LG, CD79A
5central sleep apnea30.2CD40LG, CD79A
6salivary gland adenoid cystic carcinoma10.8
7adenoid hypertrophy10.8
8adenocarcinoma10.7
9adenoid squamous cell carcinoma10.6
10otitis media10.6
11polymorphous low-grade adenocarcinoma10.6
12tonsillitis10.6
13cervical adenoid cystic carcinoma10.5
14adenoma10.5
15basal cell carcinoma10.5
16lacrimal gland adenoid cystic carcinoma10.5
17pleomorphic adenoma10.5
18cribriform carcinoma10.5
19adenoid basal cell carcinoma10.5
20laryngeal adenoid cystic carcinoma10.4
21mucoepidermoid carcinoma10.4
22cervical adenocarcinoma10.4
23oral cavity cancer10.4
24oral cancer10.4
25breast adenoid cystic carcinoma10.3
26salivary gland cancer10.3
27endotheliitis10.3
28primary cutaneous gamma/delta-positive t-cell lymphoma10.3BCL10, MALT1
29fibroosseous pseudotumor of digits10.3CD79A, LTF
30olecranon bursitis10.3CD40LG, CD79A
31bilateral hyperactive labyrinth10.3CD40LG, CD79A
32baat-related familial hypercholanemia10.3BCL10, MALT1
33calabro syndrome10.3CD40LG, CD79A
34pulmonary edema10.3CD40LG, CD79A
35ovarian malignant mesothelioma10.3CD40LG, CD79A
36photoallergic dermatitis10.3CD40LG, CD79A
37tuberculous epididymitis10.3CD40LG, CD79A
38mammary paget's disease10.3CD40LG, CD79A
39sinusitis10.3
40maxillary sinus adenoid cystic carcinoma10.3
41laryngitis10.3
42salivary gland cancer, adult10.3
43malignant epithelial tumor of salivary glands10.3
44bilateral retinoblastoma10.3CD40LG, CD79A
45cryoglobulinemia, familial mixed10.3CD40LG, CD79A
46lichen planus10.3CD40LG, CD79A
47clear cell cystadenofibroma10.3CD40LG, CD79A
48immunotactoid glomerulopathy10.3CD40LG, CD79A
49cocaine dependence10.3CD40LG, CD79A
50hepatic cystic hamartoma10.3CD40LG, CD79A

Graphical network of the top 20 diseases related to Adenoiditis:



Diseases related to adenoiditis

Symptoms for Adenoiditis

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Symptoms:

 10
  • pain
  • redness
  • swelling
  • difficulty swallowing

Drugs & Therapeutics for Adenoiditis

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Drugs for Adenoiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DexmedetomidineapprovedPhase 4420113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
2Adrenergic alpha-2 Receptor AgonistsPhase 4732

Interventional clinical trials:

idNameStatusNCT IDPhase
1The Effect of Dexmedetomidine on Airway Complications After Deep or Awake ExtubationRecruitingNCT02162433Phase 4

Search NIH Clinical Center for Adenoiditis

Genetic Tests for Adenoiditis

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Anatomical Context for Adenoiditis

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MalaCards organs/tissues related to Adenoiditis:

33
Salivary gland, Breast, Tonsil, Lung, Trachea, Skin, Tongue

Animal Models for Adenoiditis or affiliated genes

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MGI Mouse Phenotypes related to Adenoiditis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053907.6CD40LG, CD68, CD69, RING1, SRC, SYK
2MP:00053975.5BCL10, CARD9, CD40LG, CD68, CD69, CD79A
3MP:00053874.9BCL10, CARD9, CD209, CD40LG, CD68, CD69

Publications for Adenoiditis

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Articles related to Adenoiditis:

(show top 50)    (show all 895)
idTitleAuthorsYear
1
C-kit induces epithelial-mesenchymal transition and contributes to salivary adenoid cystic cancer progression. (24721839)
2014
2
CXCR4 antagonist inhibits perineural invasion of adenoid cystic carcinoma. (25118295)
2014
3
Induction of autophagy-dependent cell death by the survivin suppressant YM155 in salivary adenoid cystic carcinoma. (24370995)
2013
4
Adenoid cystic carcinoma in the bronchus behaves more aggressively than its tracheal counterpart. (24094522)
2013
5
Adenoid cystic carcinoma of palate: A case report and review of literature. (23946749)
2013
6
High grade transformation in a case of adenoid cystic carcinoma associated with Epstein-Barr virus expression. (24247629)
2013
7
Immunohistochemical clue for the histological overlap of salivary adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma. (24265903)
2013
8
Analysis of failure in patients with adenoid cystic carcinoma of the head and neck. An international collaborative study. (23784851)
2013
9
EMMPRIN contributes to the in vitro invasion of human salivary adenoid cystic carcinoma cells. (22200897)
2012
10
Molecular biology of adenoid cystic carcinoma. (22006498)
2012
11
Differential expression of aquaporin 5 and aquaporin 3 in squamous cell carcinoma and adenoid cystic carcinoma. (22576684)
2012
12
Adenoid cystic carcinoma of the airway: a 30-year review at one institution. (21907453)
2012
13
Dysphagia due to adenoid cystic carcinoma of the base of the tongue. (22737963)
2012
14
Adenoid cystic carcinoma of the breast diagnosed by fine needle aspiration. (21366736)
2012
15
A primary cutaneous adenoid-cystic carcinoma in a young woman. Differential diagnosis and clinical implications. (21464876)
2011
16
Dedifferentiated adenoid cystic carcinoma of the lacrimal gland. (21283029)
2011
17
Adenoid cystic carcinoma of the base of the tongue: Late metastasis to the pancreas. (22096672)
2011
18
Prognostic value of quantitative p63 immunostaining in adenoid cystic carcinoma of salivary gland assessed by computerized image analysis. (19877114)
2010
19
Prognostic significance of nuclear survivin expression in resected adenoid cystic carcinoma of the head and neck. (21034499)
2010
20
Primary cutaneous adenoid cystic carcinoma in the United States: incidence, survival, and associated cancers, 1976 to 2005. (20447723)
2010
21
Conservative treatment of a rare case of multifocal adenoid cystic carcinoma of the breast: case report and literature review. (20190690)
2010
22
Expression of p-AKT characterizes adenoid cystic carcinomas of head and neck with a higher risk for tumor relapses. (19545368)
2009
23
Metastasectomy for hepatic metastases from adenoid cystic carcinoma of the trachea. (20431735)
2009
24
The development of primary cutaneous adenoid cystic carcinoma in a patient with ankylosing spondylitis treated with etanercept. (19488017)
2009
25
Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. (19031084)
2009
26
Effects of basic fibroblast growth factor on the proliferation of human salivary adenoid cystic carcinoma cell line ACC-2 and extracellular signal-regulated kinase, Cyclin D1, p2waf/cip1 signaling pathway]. (18605443)
2008
27
Adenoid cystic carcinoma of trachea treated with adjuvant hypofractionated tomotherapy. Case report and literature review. (18468347)
2008
28
Adenoid cystic/basal cell carcinoma of the prostate. (18295260)
2008
29
High expression of Polycomb group protein EZH2 predicts poor survival in salivary gland adenoid cystic carcinoma. (18326020)
2008
30
The selective expression of CD43 in adenoid cystic carcinoma. (18227725)
2008
31
Papillary adenoid hyperplasia in focal dermal hypoplasia. (18503862)
2008
32
Expression of neural cell adhesion molecule in salivary adenoid cystic carcinoma and its correlation with perineural invasion. (17982624)
2007
33
A phase II study of Imatinib for advanced adenoid cystic carcinoma of head and neck salivary glands. (16757202)
2007
34
Cytodiagnosis of adenoid cystic carcinoma of the breast. (17883166)
2007
35
Unresectable adenoid cystic carcinoma of the trachea treated with chemoradiation. (18048830)
2007
36
Gene expression profile of salivary adenoid cystic carcinoma associated with perineural invasion. (17592219)
2007
37
Toll-like receptor expression in the human nasopharyngeal tonsil (adenoid) and palantine tonsils: a preliminary report. (16325925)
2006
38
Immunoreactivity for c-kit and p63 as an adjunct in the diagnosis of adenoid cystic carcinoma of the breast. (15846389)
2005
39
Tracheobronchial adenoid cystic carcinoma: a clinicopathologic study of 14 cases. (15006985)
2004
40
Differential expression of basement membrane type-IV collagen alpha1, alpha2, alpha5 and alpha6 chains among the histological subtypes of adenoid cystic carcinoma. (15138813)
2004
41
Adenoid cystic carcinoma with hyperostosis after stereotactic radiosurgery. (15287538)
2004
42
Assessment of p63 expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and basal cell and canalicular adenomas. (15153875)
2004
43
Urokinase-type plasminogen activator receptor expression in adenoid cystic carcinoma of the skull base. (12578452)
2003
44
A case of adenoid cystic carcinoma (ACC) of the breast and review of the utility of preoperative imaging diagnose. (11180772)
2001
45
Effect of amoxycillin with or without clavulanate on adenoid bacterial flora. (11481299)
2001
46
Detection of neuroendocrine feature about salivary adenoid cystic carcinoma]. (12539703)
1999
47
Oral adenoid squamous cell carcinoma: a report of three cases and review of the literature. (8492207)
1993
48
Expressions of oncogene products in adenoid cystic carcinomas of salivary glands: immunohistochemical study]. (1665502)
1991
49
Adenoid basal cell carcinoma of the vulva. (7185765)
1982
50
Multiple adenoid squamous cell carcinoma. (5093173)
1971

Variations for Adenoiditis

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Expression for genes affiliated with Adenoiditis

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Search GEO for disease gene expression data for Adenoiditis.

Pathways for genes affiliated with Adenoiditis

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Pathways related to Adenoiditis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8SRC, SYK
2
Show member pathways
9.3BCL10, CD40LG, MALT1, SYK
39.3BCL10, CD40LG, MALT1, SYK
4
B cell receptor signaling pathway (KEGG)
Show member pathways
9.1BCL10, CD40LG, MALT1, SYK
58.9BCL10, CARD9, CD209, MALT1, SRC, SYK
6
Show member pathways
8.9BCL10, CARD9, CD209, MALT1, SRC, SYK
7
Show member pathways
8.9BCL10, CARD9, CD209, MALT1, SRC, SYK
88.7BCL10, CARD9, CD40LG, CD79A, MALT1, SYK
9
Show member pathways
8.3BCL10, CD79A, MALT1, SRC, SYK, TREM1
10
Show member pathways
7.0BCL10, CARD9, CD209, CD40LG, CD79A, HAVCR2

GO Terms for genes affiliated with Adenoiditis

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Cellular components related to Adenoiditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1CBM complexGO:003244910.5BCL10, MALT1
2B cell receptor complexGO:001981510.5CD79A, SYK
3T cell receptor complexGO:004210110.5BCL10, SYK
4protein complexGO:00432348.7BCL10, FKBP4, LTF, MALT1, SYK
5plasma membraneGO:00058866.7BCL10, CARD9, CD209, CD40LG, CD68, CD79A

Biological processes related to Adenoiditis according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1macrophage activation involved in immune responseGO:000228110.6SYK, TYROBP
2neutrophil activation involved in immune responseGO:000228310.6SYK, TYROBP
3regulation of T cell receptor signaling pathwayGO:005085610.5BCL10, MALT1
4response to molecule of bacterial originGO:000223710.3BCL10, MALT1
5response to fungusGO:000962010.2BCL10, CARD9, MALT1
6leukocyte cell-cell adhesionGO:000715910.1CD209, CD40LG, SYK
7adaptive immune responseGO:00022509.9BCL10, CD209, CD79A, SYK
8positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431239.9BCL10, CARD9, LTF, MALT1
9integrin-mediated signaling pathwayGO:00072299.8SRC, SYK, TYROBP
10stimulatory C-type lectin receptor signaling pathwayGO:00022239.3BCL10, CARD9, CD209, MALT1, SRC, SYK
11intracellular signal transductionGO:00355568.8CD209, SRC, SYK, TREM1, TYROBP
12innate immune responseGO:00450878.2BCL10, CARD9, CD209, MALT1, SRC, SYK

Molecular functions related to Adenoiditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1kinase activator activityGO:001920910.7BCL10, MALT1
2protein bindingGO:00055154.4BCL10, CARD9, CD209, CD40LG, CD69, CD79A

Sources for Adenoiditis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet