Aliases & Classifications for Adenoma

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 61UMLS, 39NCIt, 56SNOMED-CT, 33MeSH
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Aliases & Descriptions for Adenoma:

Name: Adenoma 8 10 44 61
Acinar Cell Adenoma 8 61
 
Acinic Cell Adenoma 8
Adenomas 8


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Disease Ontology8 DOID:657
NCIt39 C2855
MeSH33 D000236

Summaries for Adenoma

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Disease Ontology:8 A cell type benign neoplasm that is composed of epithelial tissue in which tumor cells form glands or glandlike structures.

MalaCards based summary: Adenoma, also known as acinar cell adenoma, is related to pleomorphic adenoma and lung adenoma. An important gene associated with Adenoma is PLAGL1 (pleiomorphic adenoma gene-like 1), and among its related pathways are G-AlphaQ Signaling and Calcium signaling pathway. The drugs octreotide and octreotide acetate and the compounds acth and isoproterenol have been mentioned in the context of this disorder. Affiliated tissues include pituitary, thyroid and colon, and related mouse phenotypes are behavior/neurological and growth/size/body.

Wikipedia:64 An adenoma (from Greek ??????, adeno-, \"gland\" + -???, -oma, \"tumor\") (/? more...

Related Diseases for Adenoma

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Graphical network of the top 20 diseases related to Adenoma:



Diseases related to adenoma

Symptoms for Adenoma

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Drugs & Therapeutics for Adenoma

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Drug clinical trials:

Search ClinicalTrials for Adenoma

Search NIH Clinical Center for Adenoma

Inferred drug relations via UMLS61/NDF-RT40:

Genetic Tests for Adenoma

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Anatomical Context for Adenoma

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MalaCards organs/tissues related to Adenoma:

31
Pituitary, Thyroid, Colon, Salivary gland, Prostate, Lung, Pancreas, Kidney, Liver, Bone, Breast, Testes, Endothelial, Adrenal gland, Cervix, Ovary, Trachea, Appendix, Cortex, Skin, Adrenal cortex, Tongue, Bone marrow, Lymph node, Small intestine, Smooth muscle, Brain, Uterus, Placenta, Testis, B cells, Eye, Thymus, Monocytes, Myeloid, T cells, Hypothalamus, Pons, Neutrophil

Animal Models for Adenoma or affiliated genes

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MGI Mouse Phenotypes related to Adenoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053869.4ADCY5, ADCY8, ADCY7, ADCY1, ADCY6, KRAS
2MP:00053788.9LHCGR, LIFR, ADCY3, ADCY8, PLAGL1, PLAG1
3MP:00053768.9SLC26A3, LHCGR, LIFR, ADCY5, ADCY8, ADCY1

Publications for Adenoma

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Articles related to Adenoma:

(show top 50)    (show all 6465)
idTitleAuthorsYear
1
A rare case of a parathyroid adenoma inside a parathyroid cyst. (25372589)
2014
2
Nephrogenic adenoma of the urethra presenting as hematuria. (25177122)
2014
3
Brown tumor in a patient with ectopic mediastinal parathyroid adenoma: A case report. (25408600)
2014
4
Coexisting pancreatic mucinous cyst adenoma and adrenal lymphangioma. (25224209)
2014
5
Unusual case of Cowden-like syndrome, neck paraganglioma, and pituitary adenoma. (23804288)
2014
6
Treatment protocols for growth hormone-secreting pituitary adenomas combined with craniofacial fibrous dysplasia: A case report of atypical McCune-Albright syndrome. (25120617)
2014
7
Analysis of operative efficacy for giant pituitary adenoma. (25163653)
2014
8
Melanoma of the sellar region mimicking pituitary adenoma. (22624497)
2013
9
Neurocognitive function in acromegaly after surgical resection of GH-secreting adenoma versus naA^ve acromegaly. (23593161)
2013
10
Metachronous adenoma on ileorectal anastomosis suture line and submucosal deep invasive cancer suspected of rapid growth in rectal remnant following long-term interval after curative surgery for advanced colon cancer. (23617649)
2013
11
Mucinous adenocarcinoma arising from diffuse serrated adenoma of the appendix which mimics appendicular abscess. (23012662)
2012
12
Somatotroph pituitary adenoma with acromegaly and autosomal dominant polycystic kidney disease: SSTR5 polymorphism and PKD1 mutation. (21744088)
2012
13
TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression. (22207630)
2012
14
Case of telangiectatic/inflammatory hepatocellular adenoma arising in a patient with primary sclerosing cholangitis. (22568458)
2012
15
Elevated C-peptide and insulin predict increased risk of colorectal adenomas in normal mucosa. (22950808)
2012
16
Giant parathyroid adenoma. (22610816)
2011
17
Generalized glucocorticoid resistance accompanied with an adrenocortical adenoma and caused by a novel point mutation of human glucocorticoid receptor gene. (21362280)
2011
18
Use of morning serum cortisol level after transsphenoidal resection of pituitary adenoma to predict the need for long-term glucocorticoid supplementation. (19326985)
2009
19
Familial adenomatous polyposis-associated ampullary adenoma: response to chemotherapy for concurrent metastatic adenocarcinoma. (19245848)
2009
20
An immunohistochemical study of colon adenomas and carcinomas: E-cadherin, Syndecan-1, Ets-1. (19253033)
2009
21
Primary hyperaldosteronism in a domestic ferret with an adrenocortical adenoma. (19180717)
2008
22
Presence of HIF-1 and related genes in normal mucosa, adenomas and carcinomas of the colorectum. (18351386)
2008
23
Enteroendocrine precursors differentiate independently of Wnt and form serotonin expressing adenomas in response to active beta-catenin. (17592150)
2007
24
Ghrelin stimulates adrenocorticotrophic hormone (ACTH) secretion by human ACTH-secreting pituitary adenomas in vitro. (17280594)
2007
25
Pituitary tumour transforming gene (PTTG) expression correlates with the proliferative activity and recurrence status of pituitary adenomas: a clinical and immunohistochemical study. (16984249)
2006
26
Genetic mutation in hepatic adenoma: seeing is believing. (17034896)
2006
27
Interesting Case: Maxillary swing approach for resection of a large pleomorphic adenoma arising in the soft palate. (16055235)
2006
28
Magnetic resonance findings of bile duct adenoma with calcification. (16958429)
2006
29
An unusual somatotropin and thyreotropin secreting pituitary adenoma efficiently controlled by Octreotide and Pegvisomant. (16840917)
2006
30
Adrenal pheochromocytoma with contralateral cortisol-producing adrenal adenoma: diagnostic and therapeutic management. (16001333)
2005
31
Carcinosarcoma of the lacrimal gland arising from a pleomorphic adenoma. (16086968)
2005
32
Intrathyroidal parathyroid adenoma. (15965320)
2005
33
Genetic polymorphisms of flavin monooxygenase 3 in sulindac-induced regression of colorectal adenomas in familial adenomatous polyposis. (16214918)
2005
34
KRAS transitions and villous growth in colorectal adenomas. (16373972)
2005
35
Immunohistochemical staining of cathepsins B, L and stefin A in human hypophysis and pituitary adenomas. (15816632)
2005
36
Non-functioning pituitary adenomas: clinical features and immunohistochemistry]. (16400431)
2005
37
Chimerism of metanephric adenoma but not of carcinoma in kidney transplants. (15579450)
2004
38
Visual vignette. Hyperparathyroidism due to a parathyroid adenoma. (11441818)
2000
39
A case of aldosterone-producing adenoma with severe postoperative hyperkalemia. (10348217)
1998
40
Papillary adenoma of the large intestine: a historical perspective. (9731879)
1998
41
Pancreastatin secretion by pituitary adenomas and regulation of chromogranin B mRNA expression. (8669489)
1996
42
Effects of long-term treatment with the gonadotropin-releasing hormone analog nafarelin in patients with non-functioning pituitary adenomas. (8162161)
1994
43
Unusual scintigraphic findings in a thyroid adenoma. (8441041)
1993
44
Clinical application of 11C-NMSP to the patients with pituitary adenoma other than prolactinoma]. (8345693)
1993
45
Decay-accelerating factor (DAF, CD55) in normal colorectal mucosa, adenomas and carcinomas. (1384641)
1992
46
Peutz-Jeghers syndrome in association with adenoma malignum (minimal deviation adenocarcinoma) of the cervix. Case report. (2804013)
1989
47
Solitary hyperfunctioning thyroid adenoma in a child. Elevated T3 and T4 levels with normal TSH level. (1242753)
1975
48
Testosterone-secreting adrenal adenoma under gonadotropin control. (4728749)
1973
49
Remission of Cushing's syndrome after unilateral adrenal phlebography. Apparent destruction of adrenal adenoma. (4319080)
1970
50
Fibro-adenoma of the ovary with ascites and hydrothorax (Meigs' syndrome). (14814476)
1951

Variations for Adenoma

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Expression for genes affiliated with Adenoma

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Search GEO for disease gene expression data for Adenoma.

Pathways for genes affiliated with Adenoma

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Pathways related to Adenoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 64)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
10.3ADCY1
29.1ADCY3, ADCY8, ADCY7, ADCY9, ADCY4, ADCY1
3
Show member pathways
8.9ADCY9, ADCY4, ADCY1, ADCY2, ADCY6, ADCY7
48.9ADCY6, ADCY2, ADCY1, ADCY4, ADCY9, ADCY7
5
Show member pathways
Calcium Regulation in the Cardiac Cell36
8.9ADCY3, ADCY6, ADCY5, ADCY8, ADCY7, ADCY9
68.9ADCY6, ADCY2, ADCY1, ADCY4, ADCY9, ADCY7
7
Show member pathways
8.9ADCY2, ADCY1, ADCY4, ADCY6, ADCY7, ADCY8
8
Show member pathways
8.9ADCY5, ADCY8, ADCY7, ADCY9, ADCY4, ADCY1
98.9ADCY6, ADCY2, ADCY1, ADCY4, ADCY9, ADCY7
108.9ADCY6, ADCY2, ADCY1, ADCY4, ADCY9, ADCY7
11
Show member pathways
8.9ADCY1, ADCY2, ADCY6, ADCY4, ADCY9, ADCY7
12
Show member pathways
8.9ADCY4, ADCY1, ADCY2, ADCY7, ADCY3, ADCY8
138.9ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
14
Show member pathways
8.9ADCY6, ADCY4, ADCY9, ADCY7, ADCY1, ADCY8
15
Show member pathways
8.9ADCY4, ADCY6, ADCY3, ADCY2, ADCY8, ADCY1
16
Show member pathways
Arrhythmogenic right ventricular cardiomyopathy36
8.9ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
178.9ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
18
Show member pathways
UTP and CTP dephosphorylation II36
ATP ITP metabolism59
purine deoxyribonucleosides salvage36
8.9ADCY1, ADCY3, ADCY2, ADCY4, ADCY9, ADCY7
19
Show member pathways
8.9ADCY2, ADCY1, ADCY3, ADCY5, ADCY8, ADCY7
208.9ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
21
Show member pathways
8.9ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
22
Show member pathways
8.9ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
23
Show member pathways
Development Beta adrenergic receptors regulation of ERK59
G protein signaling G Protein alpha s signaling cascades59
G protein signaling G Protein beta gamma signaling cascades59
8.9ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
24
Show member pathways
8.9ADCY7, ADCY9, ADCY4, ADCY1, ADCY2, ADCY8
25
Show member pathways
8.9ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
26
Show member pathways
8.9ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
27
Show member pathways
8.9ADCY5, ADCY1, ADCY2, ADCY4, ADCY9, ADCY7
288.9ADCY9, ADCY5, ADCY8, ADCY7, ADCY4, ADCY1
298.8ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
30
Show member pathways
8.8ADCY9, ADCY5, ADCY8, ADCY7, ADCY4, ADCY1
31
Show member pathways
8.8ADCY1, ADCY3, ADCY2, ADCY4, ADCY9, ADCY7
32
Show member pathways
8.8ADCY3, LIFR, ADCY2, ADCY5, ADCY8, ADCY6
33
Show member pathways
8.8ADCY3, ADCY2, ADCY1, ADCY4, ADCY9, ADCY7
34
Show member pathways
8.8ADCY3, ADCY5, ADCY8, ADCY9, ADCY7, LIFR
358.8LHCGR, ADCY3, ADCY8, ADCY7, ADCY6, ADCY2
36
Show member pathways
8.8LHCGR, ADCY3, ADCY5, ADCY8, ADCY7, ADCY9
37
Show member pathways
8.8LHCGR, ADCY3, ADCY5, ADCY8, ADCY7, ADCY1
388.8ADCY5, ADCY3, ADCY6, ADCY2, ADCY1, ADCY4
39
Show member pathways
8.8ADCY2, ADCY6, ADCY1, ADCY4, ADCY9, ADCY7
40
Show member pathways
8.8ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
41
Show member pathways
8.8ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
428.8ADCY1, ADCY4, ADCY9, ADCY7, ADCY8, ADCY5
43
Show member pathways
8.8KRAS, ADCY6, ADCY2, ADCY7, ADCY1, ADCY3
44
Show member pathways
8.8ADCY3, ADCY5, ADCY8, ADCY7, ADCY4, ADCY1
45
Show member pathways
8.8KRAS, ADCY6, ADCY2, ADCY1, ADCY7, ADCY8
46
Show member pathways
8.8ADCY3, ADCY5, KRAS, ADCY6, ADCY2, ADCY1
47
Show member pathways
Signal transduction cAMP signaling59
8.8ADCY7, ADCY9, ADCY4, ADCY1, ADCY2, ADCY6
48
Show member pathways
Cytoskeleton remodeling FAK signaling59
Development Endothelin 1 EDNRA transactivation of EGFR59
8.8KRAS, ADCY7, ADCY8, ADCY5, ADCY3, ADCY9
49
Show member pathways
8.8ADCY9, ADCY7, ADCY8, ADCY5, ADCY3, ADCY6

Compounds for genes affiliated with Adenoma

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Compounds related to Adenoma according to GeneCards Suite gene sharing:

(show all 21)
idCompoundScoreTop Affiliating Genes
1acth4410.0LHCGR, LIFR, ADCY1
2isoproterenol44 1110.6ADCY7, ADCY3, ADCY2, LHCGR, ADCY1
3dopamine44 28 24 1112.5ADCY6, ADCY5, ADCY1, ADCY2
4adenylate449.4ADCY5, ADCY3, LHCGR, ADCY1, ADCY9, PLAGL1
5forskolin44 50 1111.3ADCY3, LHCGR, ADCY5, ADCY7, ADCY9, ADCY1
6nkh 477609.2ADCY5, ADCY3, ADCY8, ADCY7, ADCY9, ADCY6
7kh 7609.2ADCY6, ADCY2, ADCY1, ADCY4, ADCY9, ADCY7
8pacap 1-27609.2ADCY6, ADCY2, ADCY1, ADCY4, ADCY9, ADCY7
9sq 2253644 6010.2ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
10Pyruvic acid24 1110.2ADCY3, ADCY6, ADCY2, ADCY1, ADCY4, ADCY9
11Cyclic GMP249.2ADCY1, ADCY4, ADCY9, ADCY7, ADCY5, ADCY3
12mdl 12330a hydrochloride609.2ADCY6, ADCY2, ADCY1, ADCY4, ADCY9, ADCY3
13nad28 2410.2ADCY2, ADCY1, ADCY4, ADCY9, ADCY3, ADCY7
14phosphoric acid44 2410.2ADCY6, ADCY5, ADCY3, ADCY8, ADCY7, ADCY9
15pyrophosphate44 2410.2ADCY7, ADCY8, ADCY5, ADCY3, ADCY9, ADCY4
16nadh44 24 1111.1ADCY2, ADCY6, ADCY1, ADCY4, ADCY9, ADCY7
17magnesium44 24 1111.1ADCY1, ADCY4, ADCY9, ADCY7, ADCY8, ADCY3
18Adenosine triphosphate24 1110.0ADCY8, ADCY3, ADCY9, ADCY1, ADCY2, ADCY6
19Guanosine triphosphate249.0ADCY2, ADCY6, KRAS, ADCY5, ADCY1, ADCY4
20cyclic amp44 2410.0LHCGR, ADCY3, ADCY5, ADCY8, ADCY7, ADCY9
21calcium44 50 24 1111.7ADCY7, ADCY2, ADCY5, ADCY1, ADCY8, ADCY4

GO Terms for genes affiliated with Adenoma

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Cellular components related to Adenoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1membraneGO:00160209.6ADCY4, ADCY2, ADCY6, SLC26A3, ADCY8
2plasma membraneGO:00058868.2SLC26A3, LHCGR, ADCY3, ADCY5, ADCY8, ADCY7

Biological processes related to Adenoma according to GeneCards Suite gene sharing:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1adenylate cyclase-modulating G-protein coupled receptor signaling pathwayGO:000718810.1ADCY4, ADCY2
2long-term memoryGO:00076169.8ADCY1, ADCY8
3cAMP biosynthetic processGO:00061719.8ADCY6, ADCY2, ADCY4
4adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayGO:00071939.2ADCY4, ADCY9, ADCY7, ADCY8, ADCY5, ADCY3
5activation of phospholipase C activityGO:00072029.2ADCY3, ADCY5, ADCY8, ADCY6, ADCY2, ADCY1
6activation of protein kinase A activityGO:00341999.2ADCY5, ADCY6, ADCY2, ADCY1, ADCY4, ADCY9
7cellular response to glucagon stimulusGO:00713779.2ADCY6, ADCY2, ADCY1, ADCY4, ADCY9, ADCY7
8water transportGO:00068339.2ADCY5, ADCY6, ADCY2, ADCY1, ADCY4, ADCY9
9energy reserve metabolic processGO:00061129.2ADCY5, ADCY3, ADCY8, ADCY7, ADCY9, ADCY2
10adenylate cyclase-activating G-protein coupled receptor signaling pathwayGO:00071899.1ADCY4, ADCY9, ADCY7, ADCY8, ADCY5, ADCY3
11intracellular signal transductionGO:00355569.1ADCY4, ADCY9, ADCY7, ADCY8, ADCY5, ADCY3
12fibroblast growth factor receptor signaling pathwayGO:00085439.1KRAS, ADCY6, ADCY2, ADCY1, ADCY4, ADCY9
13neurotrophin TRK receptor signaling pathwayGO:00480119.1ADCY7, ADCY8, ADCY5, ADCY3, ADCY9, ADCY4
14synaptic transmissionGO:00072689.0ADCY8, ADCY5, ADCY6, ADCY2, ADCY3, ADCY1
15epidermal growth factor receptor signaling pathwayGO:00071739.0ADCY7, ADCY9, ADCY4, ADCY1, ADCY2, ADCY6
16signal transductionGO:00071659.0ADCY7, ADCY4, ADCY1, ADCY8, ADCY5, ADCY3
17transmembrane transportGO:00550859.0ADCY8, ADCY7, ADCY9, ADCY4, ADCY1, ADCY2
18small molecule metabolic processGO:00442818.9ADCY2, ADCY6, ADCY1, ADCY4, ADCY9, ADCY8
19innate immune responseGO:00450878.9ADCY6, KRAS, ADCY3, ADCY5, ADCY8, ADCY7

Molecular functions related to Adenoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1adenylate cyclase bindingGO:000817910.1ADCY2, ADCY5
2calcium- and calmodulin-responsive adenylate cyclase activityGO:00082949.8ADCY8, ADCY1, ADCY2
3adenylate cyclase activityGO:00040169.2ADCY6, ADCY3, ADCY5, ADCY8, ADCY7, ADCY9
4ATP bindingGO:00055248.6ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4
5metal ion bindingGO:00468728.4ADCY3, ADCY5, ADCY8, ADCY7, ADCY9, ADCY4

Sources for Adenoma

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet