MCID: ADR008
MIFTS: 57

Adrenal Adenoma malady

Endocrine, Cancer categories

Summaries for Adrenal Adenoma

Sources:
43NIH Rare Diseases, 64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
NIH Rare Diseases:43 An adenoma of the adrenal gland is a non-cancerous (benign) tumor on the adrenal gland. it can develop at any age but is more common in people between the ages of 40 and 60; people over age 70 are at significantly higher risk. it typically causes no complications, but in some cases, can cause severe problems. sometimes these tumors become "active" or "functioning" which means they produce hormones, often in excess of what the adrenal glands typically produce. this can have negative effects on an individual's health, potentially causing primary aldosteronism, cushing's syndrome and other medical conditions. most benign adrenal tumors are non-functioning and do not need immediate treatment, but some may become functioning and require treatment including medications or surgery. last updated: 10/24/2011

MalaCards: Adrenal Adenoma, also known as adenoma of the adrenal gland, is related to adenoma and cushing's syndrome. An important gene associated with Adrenal Adenoma is HSD11B2 (hydroxysteroid (11-beta) dehydrogenase 2), and among its related pathways are Glucocorticoid Pathway (HPA Axis), Pharmacodynamics and Prostaglandin Synthesis and Regulation. The compounds estrogen and pcb 126 have been mentioned in the context of this disorder. Affiliated tissues include ovary, liver and kidney, and related mouse phenotypes are muscle and endocrine/exocrine gland.

Wikipedia:64 A adrenal adenoma is a benign tumor of the glandular type (adenoma) in the adrenal gland. While some... more...

Aliases & Classifications for Adrenal Adenoma

Sources:
8Disease Ontology, 43NIH Rare Diseases, 10DISEASES, 45Novoseek, 61UMLS, 49Orphanet, 36MESH via Orphanet, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer
Anatomical: Endocrine


Characteristics (Orphanet epidemiological data):

49
adrenal incidentaloma:
Inheritance: Sporadic; Age of onset: Adulthood


Aliases & Descriptions:

adrenal adenoma 8 43 10 45
adenoma of the adrenal gland 8 43
adrenal cortical adenoma 43 61
adrenal incidentaloma 43 49
adrenocortical adenoma 43
adenoma adrenocortical 45


External Ids:

Disease Ontology8 DOID:656
MESH via Orphanet36 C538238
ICD10 via Orphanet26 D35.0
SNOMED-CT via Orphanet58 127021009
UMLS via Orphanet62 C2609247

Related Diseases for Adrenal Adenoma

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Adrenal Adenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 189)
idRelated DiseaseScoreTop Affiliating Genes
1adenoma31.8GIPR, CNC, CDKN1C, CYP11B1, CYP11B2, CYP17A1
2cushing's syndrome31.3HSD11B2, CRH, POMC
3conn's syndrome30.7POMC, CYP11B1, CYP11B2, REN
4adrenal carcinoma30.5POMC
5pheochromocytoma30.5GNAS, H19, CRH, MEN1, POMC, ADM
6amenorrhea30.4CRH, POMC
7adrenocortical carcinoma30.4PRKAR1A, MC2R
8multiple endocrine neoplasia30.3GNAS, MEN1, PRKAR1A, CNC
9hypokalemia30.3HSD11B2, POMC, CYP11B2, CYP17A1, REN
10thyroid adenoma30.3CNC, PRKAR1A, GNAS
11precocious puberty30.2GNAS, POMC, CYP11B1, CYP21A2
12hyperandrogenism30.2GNAS, CRH, POMC, CYP17A1, CYP21A2, CYP11A1
13adenocarcinoma30.2HSD11B2, HSD11B1, H19, MEN1, CDKN1C, CYP21A2
14congenital adrenal hyperplasia30.2CRH, POMC, CYP11B1, CYP11B2, CYP17A1, CYP21A2
15paraganglioma30.2MEN1
16insulin resistance30.1HSD11B2, HSD11B1, GNAS, CYP17A1, CYP21A2
17wermer syndrome30.1PRKAR1A, MEN1
18gynecomastia30.0CYP17A1
19arthritis30.0POMC
20renovascular hypertension30.0ADM, REN
21acth deficiency30.0POMC, CRH, HSD11B1
22osteoporosis30.0CYP21A2, PRKAR1A, HSD11B1, HSD11B2
23hemihypertrophy30.0H19, CDKN1C
24hyperprolactinemia30.0POMC, CRH, GNAS
25carney complex30.0POMC, PRKAR1A, MEN1, GNAS
26prolactinoma30.0GNAS, MEN1, PRKAR1A, POMC, ADCY10
27addison's disease30.0MC2R, REN, CYP11A1, CYP21A2, CYP17A1, CRH
28acromegaly30.0ADCY10, HSD11B2, HSD11B1, GNAS, CRH, MEN1
29pregnancy adenoma10.4
30ganglioneuroma10.3
31n syndrome10.3
32extramedullary plasmacytoma10.3
33beckwith-wiedemann syndrome10.2
34primary pigmented nodular adrenocortical disease10.2
35carney triad10.2
36glucagonoma10.2
37pancreatic adenoma10.2
38adult syndrome10.2
39familial hyperaldosteronism type 210.2
40gardner syndrome10.2
41adrenal adenoma, somatic10.2
42inflammatory myofibroblastic tumor10.1
43mass syndrome10.1
44virilizing ovarian tumor10.1
45teratoma10.1
46papillary carcinoma10.1
47primary hyperparathyroidism10.1
48anhidrosis10.1
49gastrointestinal stromal tumor10.1
50fetal adenoma10.1

Graphical network of the top 20 diseases related to Adrenal Adenoma:



Diseases related to adrenal adenoma

Clinical Features for Adrenal Adenoma

Drugs & Therapeutics for Adrenal Adenoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Adrenal Adenoma

Drug clinical trials:

Search ClinicalTrials for Adrenal Adenoma

Search NIH Clinical Center for Adrenal Adenoma

Search CenterWatch for Adrenal Adenoma

Genetic Tests for Adrenal Adenoma

Anatomical Context for Adrenal Adenoma

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Adrenal Adenoma:

33
Ovary, Liver, Kidney, Lung, Cortex, Small intestine, Colon, Thyroid, Adrenal gland, Endothelial, Adrenal cortex, Pituitary

Animal Models for Adrenal Adenoma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Adrenal Adenoma:

37 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.8CYP11B2, H19, MEN1, PRKAR1A, CYP11A1, REN
2MP:00053799.6CYP11A1, CYP11B2, CYP11B1, CDKN1C, GIPR, MEN1
3MP:00053759.5HSD11B1, MC2R, CYP11B1, PRKAR1A, GNAS, POMC
4MP:00053709.5HSD11B1, GNAS, MEN1, POMC, CYP11B1, ADM
5MP:00053679.4REN, HSD11B2, GNAS, H19, POMC, CDKN1C
6MP:00053899.3ADCY10, REN, CYP11B1, CDKN1C, PRKAR1A, MEN1
7MP:00053978.9PRKAR1A, REN, HSD11B1, MC2R, CYP11B1, CDKN1C
8MP:00053868.9POMC, CDKN1C, CYP11B2, CYP17A1, CYP11A1, MC2R
9MP:00028738.9REN, HSD11B2, GNAS, H19, CRH, PRKAR1A
10MP:00036318.9GNAS, REN, MC2R, CYP11A1, CYP11B1, CDKN1C
11MP:00053788.9REN, POMC, CYP11A1, CYP11B2, CDKN1C, PRKAR1A
12MP:00053848.9CDKN1C, GNAS, CRH, PRKAR1A, ADM, POMC
13MP:00053878.8CYP11B1, MEN1, ADM, HSD11B1, CRH, GNAS
14MP:00053858.8H19, POMC, GNAS, MEN1, PRKAR1A, HSD11B2
15MP:00107688.7PRKAR1A, CYP11A1, CYP17A1, MC2R, REN, ADM
16MP:00053768.1HSD11B2, CYP17A1, CYP11B2, CDKN1C, GIPR, POMC

Publications for Adrenal Adenoma

Sources:
51PubMed
See all sources

Articles related to Adrenal Adenoma:

(show top 50)    (show all 397)
idTitleAuthorsYear
1
Adrenal adenoma and metastasis from clear cell renal cell carcinoma: can they be differentiated using standard MR techniques? (24252816)
2013
2
Percutaneous ablation of functioning adrenal adenoma: a report on 11 cases and a review of the literature. (23589076)
2013
3
Factors affecting complete hypertension cure after adrenalectomy for aldosterone-producing adenoma: outcomes in a large series. (23466491)
2013
4
An unusual presentation of Carney complex with diffuse primary pigmented nodular adrenocortical disease on one adrenal gland and a nonpigmented adrenocortical adenoma and focal primary pigmented nodular adrenocortical disease on the other. (22785148)
2012
5
Resistant arterial hypertension: association with syncronous kidney cancer and adrenal adenoma. (20383873)
2010
6
Virilizing adrenal adenoma in a 20 month-old girl. (19960887)
2009
7
Retroperitoneoscopic adrenalectomy in Conn's syndrome caused by adrenal adenomas or nodular hyperplasia. (18343972)
2008
8
A case of cortisol producing adrenal adenoma without phenotype of Cushing's syndrome due to impaired 11beta-hydroxysteroid dehydrogenase 1 activity. (18493111)
2008
9
Composite adenomatoid tumor and myelolipoma of adrenal gland: report of 2 cases. (18251587)
2008
10
Cytomegalovirus and BK-Virus co-infection of a clinically non-functioning adrenal adenoma: innocent bystanders or new pathogenetic agents? (16864124)
2006
11
Clinically inapparent adrenal mass in a patient with familial adenomatous polyposis. (16865001)
2006
12
Incidental pheochromocytoma mimicking adrenal adenoma because of rapid contrast enhancement loss. (17056921)
2006
13
Giant adrenal adenoma with hyperaldosteronism. (16484750)
2006
14
Comparison of adrenal vein sampling value between aldosterone producing adrenal adenoma and non-functioning adrenal adenoma: evaluation using receiver operating characteristic analysis. (16372697)
2005
15
Association of Lys173Arg polymorphism with CYP11B2 expression in normal adrenal glands and aldosterone-producing adenomas. (16118341)
2005
16
Role of local 11 beta-hydroxysteroid dehydrogenase type 2 expression in determining the phenotype of adrenal adenomas. (12574226)
2003
17
Coincidental diagnosis of an occult hilar steroid cell tumor of the ovary and a cortisol-secreting adrenal adenoma in a 49-year-old woman with severe hyperandrogenism. (14667891)
2003
18
Adrenocortical adenoma associated with inadequately treated congenital adrenal hyperplasia. (14714757)
2003
19
A case of aldosterone-producing adrenocortical adenoma associated with a probable post-operative adrenal crisis: histopathological analyses of the adrenal gland. (14567506)
2003
20
Manifestation of thyrotoxic periodic paralysis in two patients with adrenal adenomas and hyperandrogenaemia. (12784096)
2003
21
Bilateral asynchronous adrenal adenoma in a girl with an incomplete form of Beckwith-Wiedemann syndrome. (11271390)
2001
22
The patients with incidentally discovered adrenal adenoma (incidentaloma) are not at increased risk of osteoporosis. (11158016)
2001
23
Virilizing adrenal adenoma and primary amenorrhea in a girl with adrenal hyperplasia. (10763843)
2000
24
MR imaging of a case of adenomatoid tumor of the adrenal gland. (10087132)
1999
25
Expression of 11beta-hydroxysteroid dehydrogenase type 2 (11betaHSD-2) in the developing human adrenal gland and human adrenal cortical carcinoma and adenoma. (10509802)
1999
26
Adenomatoid Tumor of the Right Adrenal Gland in a Patient with AIDS. (12114672)
1997
27
Marked hypocholesterolemia in a case with adrenal adenoma--enhanced catabolism of low density lipoprotein (LDL) via the LDL receptors of tumor cells. (7829645)
1995
28
Testosterone-secreting adrenal adenoma that contained crystalloids of Reinke in an adult female patient. (7898146)
1995
29
Primary hyperaldosteronism due to an adrenal adenoma in a 14-year-old boy. (7724419)
1995
30
High expression of cytochrome b5 in adrenocortical adenomas from patients with Cushing's syndrome associated with high secretion of adrenal androgens. (8496319)
1993
31
Primary adrenocortical nodular dysplasia presented as adrenal adenoma by functional scintigraphy. (8462213)
1993
32
A case of asymptomatic cortisol producing adrenal adenoma. (1606918)
1992
33
Testosterone-secreting virilizing adrenal adenoma with human chorionic gonadotrophin receptors and 21-hydroxylase deficiency. (1848485)
1991
34
Massive hemorrhagic functional adrenal adenoma histologically mimicking angiosarcoma. Report of a case with immunohistochemical study. (2058765)
1991
35
Concurrent hypercortisolism and hyperaldosteronism due to an adrenal adenoma. (2232630)
1990
36
Evidence of 11 beta-hydroxylase deficiency in a patient with cortical adrenal adenoma. (2789167)
1989
37
A 16-year follow-up in a corticosteroid-sensitive patient with glaucoma secondary to a benign adrenal adenoma. (2923156)
1989
38
Generation of homozygosity at the c-Ha-ras-1 locus on chromosome 11p in an adrenal adenoma from an adult with Wiedemann-Beckwith syndrome. (3275489)
1988
39
Ultrastructural studies of adrenal adenoma causing primary aldosteronism. (2994287)
1985
40
Malignant hypertension due to an aldosterone producing adrenal adenoma. (3899416)
1985
41
Virilization of a post-menopausal woman by a testosterone-secreting Leydig cell type adrenal adenoma. (6270941)
1981
42
Virilizing adrenal adenoma secreting testosterone. (6275133)
1981
43
Increased 17 beta-hydroxysteroid dehydrogenase activity in a masculinizing adrenal adenoma in a patient with isolated testosterone overproduction. (6244323)
1980
44
Hyperaldosteronism with coexistence of adrenal cortical adenoma and pheochromocytoma. (288840)
1979
45
Localisation of adrenal adenoma with I 131-19 iodocholesterol. (912247)
1977
46
Feminizing adrenal adenoma in a boy. Case report and literature review. (865131)
1977
47
Coexistence of pheochromocytoma, adrenal adenoma and hypokalemia. (844017)
1977
48
Periodic hypokalaemic paralysis, adrenal adenoma, and normal colonic transport of sodium and potassium. (4719216)
1973
49
Adrenal adenoma with variable response to dexamethasone suppression and metyrapone stimulation. (5012501)
1972
50
Remission of Cushing's syndrome after unilateral adrenal phlebography. Apparent destruction of adrenal adenoma. (4319080)
1970

Genetic Variations for Adrenal Adenoma

Expression for genes affiliated with Adrenal Adenoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Adrenal Adenoma

Search GEO for disease gene expression data for Adrenal Adenoma.

Pathways for genes affiliated with Adrenal Adenoma

Sources:
50PharmGKB, 38NCBI BioSystems Database, 30KEGG, 12EMD Millipore, 54Reactome
See all sources

Pathways related to Adrenal Adenoma according to GeneCards/GeneDecks:

(show all 15)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2POMC, CRH
210.1HSD11B2, CYP11A1, HSD11B1
310.0CYP11A1, CYP17A1, GNAS
49.9REN, MC2R, CRH
5
Hide members
9.8CYP11B1, CYP11B2, CYP21A2, CYP11A1, CYP17A1
6
Hide members
9.8CYP11A1, CYP21A2, CYP17A1, CYP11B1, CYP11B2
79.8CYP17A1, CYP21A2, CYP11B1, CYP11B2, CYP11A1
8
Hide members
9.8ADM, GNAS, CRH, PRKAR1A
9
Hide members
9.7CYP11B1, CYP21A2, HSD11B1, CYP11B2, CYP11A1, CYP17A1
10
Hide members
9.6MC2R, GNAS, CRH, POMC, GIPR
11
Hide members
9.6HSD11B2, CYP11A1, CYP21A2, CYP17A1, CYP11B2, CYP11B1
12
Hide members
9.6CYP17A1, CYP11B1, HSD11B1, CYP11A1, CYP21A2, HSD11B2
13
Hide members
9.5GNAS, CRH, POMC, GIPR, MC2R, ADM
14
Hide members
9.4CYP11B2, GNAS, PRKAR1A, CYP11A1, HSD11B1, CYP21A2
15
Hide members
9.2MC2R, ADM, GIPR, POMC, PRKAR1A, MEN1

Compounds for genes affiliated with Adrenal Adenoma

Sources:
45Novoseek, 24HMDB, 29IUPHAR, 11DrugBank, 50PharmGKB, 60Tocris Bioscience, 2BitterDB
See all sources

Compounds related to Adrenal Adenoma according to GeneCards/GeneDecks:

(show top 50)    (show all 142)
idCompoundScoreTop Affiliating Genes
1estrogen4510.5HSD11B1
2pcb 1264510.3CYP17A1, CYP21A2, CYP11B2, CYP11B1
318-hydroxycorticosterone45 2411.2CYP11B2, CYP11B1, POMC, REN
4aldosterone29 11 2412.2CYP11B2, CYP11B1, ADM, CYP17A1
5hydroxysteroid4510.2HSD11B1, HSD11B2, CYP17A1, CYP11A1
621-deoxycortisol45 2411.2CYP21A2, POMC, CYP11B1, CYP11B2, CYP17A1
7fludrocortisone45 29 1112.2POMC, CYP11B2, CYP21A2, REN
8metoclopramide45 1111.2REN, CYP17A1, CYP11B2, CYP11B1
9acth 1-244510.2CRH, CYP17A1, CYP21A2, POMC, CYP11A1
10aminoglutethimide45 1111.2CYP21A2, MC2R, CYP11A1, POMC
1117beta-hydroxysteroid4510.1CYP17A1, CYP11B2, HSD11B1, CYP21A2, CYP11A1
12cortisol29 2411.1CYP21A2, CYP11B2, CYP11B1, POMC, HSD11B1, HSD11B2
13cortisone acetate45 1111.1HSD11B2, HSD11B1, CYP21A2
14ketoconazole45 29 11 2413.0CYP11B1, CYP11A1, CYP21A2, CYP17A1, POMC, CRH
15prostaglandin4510.0HSD11B1, HSD11B2, CRH, REN, ADCY10
16cortisone45 2411.0CYP21A2, CYP11B1, CYP11B2, POMC, CRH, HSD11B1
17dehydroepiandrosterone sulfate459.9CYP11A1, CRH, POMC, CYP17A1, CYP21A2, MC2R
18dbc-amp459.9CYP17A1, CYP11B2, CYP11A1, ADM, ADCY10
19spironolactone50 45 60 29 1113.9POMC, CRH, HSD11B2, REN, CYP21A2, CYP11B1
2011 deoxycortisol459.9CRH, POMC, CYP11B1, CYP11B2, CYP17A1, REN
21metyrapone60 45 1111.9HSD11B1, MC2R, CYP21A2, CYP11B2, CYP11B1, POMC
22doca459.8CYP11B1, CYP11B2, POMC, HSD11B2, REN, CYP11A1
2317-hydroxyprogesterone45 2410.8REN, CYP11A1, CYP21A2, CYP17A1, CYP11B2, CYP11B1
24pge2459.7REN, POMC, HSD11B1
25catecholamine459.7ADM, REN, CYP21A2, POMC, CRH
263beta-hydroxysteroid459.7MC2R, CYP11A1, CYP21A2, CYP17A1, CYP11B2, CYP11B1
27potassium45 11 2411.7CYP11B2, CYP11B1, CYP17A1, REN, HSD11B2, MC2R
28gnrh459.7CYP21A2, GNAS, CYP17A1, CYP11A1, POMC, CRH
29glucose459.6CYP21A2, REN, ADM, POMC, CYP11B2
30dhea459.6CYP11A1, CYP21A2, CYP17A1, CYP11B2, POMC, CRH
31sodium45 2410.6HSD11B2, HSD11B1, REN, CYP11B1, CYP11B2, CYP21A2
32estradiol45 11 2411.6CYP11A1, HSD11B1, CRH, POMC, CYP11B1, HSD11B2
33cycloheximide459.6CRH, ADCY10, CDKN1C, CYP17A1, CYP21A2, CYP11A1
34norepinephrine45 11 2411.5HSD11B2, GNAS, CRH, POMC, CYP11B2, CYP21A2
35hydrocortisone45 2 60 1112.4CYP11B2, CYP21A2, MC2R, REN, ADM, POMC
36corticosterone45 60 2411.4HSD11B2, REN, CYP11A1, CYP21A2, CYP17A1, CYP11B2
37testosterone45 60 11 2412.4CYP11B1, HSD11B1, CRH, POMC, CYP11B2, CYP17A1
3811beta-hydroxysteroid459.4REN, HSD11B2, HSD11B1, MC2R, CYP11A1, CYP21A2
39androstenedione45 2410.4REN, HSD11B2, HSD11B1, MC2R, CYP11A1, CYP21A2
40progesterone45 60 29 11 2413.3CRH, CYP11B1, CYP11B2, CYP17A1, HSD11B1, GNAS
41cholesterol45 29 11 2412.3CYP11B1, CYP17A1, CYP21A2, CYP11A1, MC2R, REN
42forskolin45 50 1111.3ADM, REN, MC2R, HSD11B2, HSD11B1, CRH
43adenylate459.2POMC, CYP11A1, MC2R, ADM, ADCY10, PRKAR1A
44dexamethasone45 50 29 1112.1CYP11B2, CYP17A1, CYP21A2, CYP11A1, MC2R, REN
45cyclic amp45 2410.1CYP17A1, CYP11B1, CNC, PRKAR1A, CYP11A1, MC2R
46arginine459.1ADM, REN, CYP17A1, CYP11B2, CYP11B1, CRH
47ribonucleic acid459.0HSD11B2, CYP11A1, MC2R, CYP21A2, CYP17A1, HSD11B1
48calcium45 50 11 2411.8MC2R, CYP17A1, REN, CYP21A2, ADCY10, CYP11A1
49acth458.8REN, CYP11A1, CYP21A2, CYP17A1, CYP11B2, CDKN1C
50steroid458.6H19, CRH, PRKAR1A, POMC, CYP11B1, CYP11B2

GO Terms for genes affiliated with Adrenal Adenoma

Sources:
16Gene Ontology
See all sources

Biological processes related to Adrenal Adenoma according to GeneCards/GeneDecks:

(show all 25)
idNameGO IDScoreTop Affiliating Genes
1regulation of blood volume by renal aldosteroneGO:00201710.5CYP11B2, HSD11B2
2cortisol biosynthetic processGO:03465110.5CYP11B1, CYP11B2
3aldosterone biosynthetic processGO:03234210.5CYP11B1, CYP11B2
4response to fungicideGO:06099210.5CYP17A1, CYP11A1
5dibenzo-p-dioxin metabolic processGO:01889410.4CYP17A1, CYP11A1
6mineralocorticoid biosynthetic processGO:00670510.4CYP21A2, CYP11B2, CYP11B1
7C21-steroid hormone biosynthetic processGO:00670010.4CYP11A1, CYP11B2, CYP11B1
8biphenyl metabolic processGO:01887910.4CYP17A1, CYP11A1
9response to insecticideGO:01708510.4CYP17A1, CYP11A1
10cellular response to potassium ionGO:03586510.4CYP11B1, CYP11B2
11phthalate metabolic processGO:01896310.3CYP17A1, CYP11A1
12phenol-containing compound metabolic processGO:01895810.3CYP17A1, CYP11A1
13cAMP biosynthetic processGO:00617110.3ADCY10, ADM, GNAS
14Leydig cell differentiationGO:03332710.2CYP11A1, CYP17A1
15sterol metabolic processGO:01612510.2CYP11B1, CYP11B2, CYP17A1, CYP21A2, CYP11A1
16female pregnancyGO:00756510.2HSD11B2, GNAS, CRH, ADM
17xenobiotic metabolic processGO:00680510.2CYP11B1, CYP11B2, CYP17A1, CYP21A2, CYP11A1
18positive regulation of cAMP biosynthetic processGO:03081910.1GNAS, CRH, MC2R, ADM
19progesterone biosynthetic processGO:00670110.1CYP11A1, ADM
20glucocorticoid biosynthetic processGO:00670410.1CYP21A2, CYP17A1, CYP11B1, CRH, HSD11B1, HSD11B2
21steroid metabolic processGO:00820210.1HSD11B1, CYP11B1, CYP11B2, CYP17A1, CYP21A2, CYP11A1
22response to drugGO:04249310.1HSD11B2, GNAS, CRH, CYP17A1, CYP11A1
23regulation of blood pressureGO:00821710.0REN, CYP11B1, POMC
24cellular response to antibioticGO:0712369.9CYP11A1, CYP17A1
25small molecule metabolic processGO:0442819.6HSD11B1, GNAS, PRKAR1A, CYP11B1, CYP11B2, CYP17A1

Molecular functions related to Adrenal Adenoma according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
111-beta-hydroxysteroid dehydrogenase [NAD(P)] activityGO:00384510.3HSD11B1, HSD11B2
2steroid 11-beta-monooxygenase activityGO:00450710.2CYP11B2, CYP11B1
3heme bindingGO:02003710.0CYP11A1, CYP21A2, CYP17A1, CYP11B2, CYP11B1
4hormone activityGO:00517910.0ADM, POMC, CRH
5adenylate cyclase activityGO:00401610.0GNAS, ADCY10
6iron ion bindingGO:00550610.0CYP11B1, CYP11B2, CYP17A1, CYP21A2, CYP11A1
7electron carrier activityGO:00905510.0CYP11B1, CYP11B2, CYP17A1, CYP21A2, CYP11A1
8receptor bindingGO:0051029.5ADM, REN, POMC, CRH

Products for genes affiliated with Adrenal Adenoma

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Adrenal Adenoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet