MCID: ADR013
MIFTS: 26

Adrenal Gland Hyperfunction malady

Rare diseases, Endocrine diseases categories
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Summaries for Adrenal Gland Hyperfunction

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NINDS:43 Cushing's syndrome, also called , is a rare endocrine disorder caused by chronic exposure of the body's tissues to excess levels of cortisol - a hormone naturally produced by the adrenal gland. Exposure to too much cortisol can occur from long-term use of synthetic glucocorticoid hormones to treat inflammatory illnesses. Pituitary adenomas (benign tumors of the pituitary gland) that secrete increased amounts of ACTH ( a substance that controls the release of cortisol) can also spur overproduction of cortisol. Tumors of the adrenal gland and ectopic ACTH syndrome (a condition in which ACTH is produced by various types of potentially malignant tumors that occur in different parts of the body) can cause similar problems with cortisol balance. Common symptoms of Cushing's syndrome include upper body obesity, severe fatigue and muscle weakness, high blood pressure, backache, elevated blood sugar, easy bruising, and bluish-red stretch marks on the skin. In women, there may be increased growth of facial and body hair, and menstrual periods may become irregular or stop completely. Neurological symptoms include difficulties with memory and neuromuscular disorders.

MalaCards based summary: Adrenal Gland Hyperfunction, also known as hypercortisolism, is related to cushing's syndrome and hyperaldosteronism. The drugs fludrocortisone and fluorocortisol acetate have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, cortex and skin.

Wikipedia:65 Adrenocortical hyperfunction is a condition where there is an overexpression of products of the adrenal... more...

Aliases & Classifications for Adrenal Gland Hyperfunction

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Adrenal Gland Hyperfunction, Aliases & Descriptions:

Name: Adrenal Gland Hyperfunction 8 42 62
Hypercortisolism 8 43 44
Disorder of Corticoadrenal Overactivity 8 62
 
Adrenocortical Hyperfunction 8 62
Overproduction of Cortisol 8 62
Hyperadrenalism 8 42


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Endocrine diseases


External Ids:

Disease Ontology8 DOID:3947
MeSH34 D000308

Related Diseases for Adrenal Gland Hyperfunction

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Graphical network of the top 20 diseases related to Adrenal Gland Hyperfunction:



Diseases related to adrenal gland hyperfunction

Symptoms for Adrenal Gland Hyperfunction

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Drugs & Therapeutics for Adrenal Gland Hyperfunction

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Drug clinical trials:

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Search NIH Clinical Center for Adrenal Gland Hyperfunction

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Adrenal Gland Hyperfunction

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Anatomical Context for Adrenal Gland Hyperfunction

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MalaCards organs/tissues related to Adrenal Gland Hyperfunction:

32
Adrenal gland, Cortex, Skin, Adrenal cortex, Pituitary

Animal Models for Adrenal Gland Hyperfunction or affiliated genes

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Publications for Adrenal Gland Hyperfunction

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Variations for Adrenal Gland Hyperfunction

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Expression for genes affiliated with Adrenal Gland Hyperfunction

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Search GEO for disease gene expression data for Adrenal Gland Hyperfunction.

Pathways for genes affiliated with Adrenal Gland Hyperfunction

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Compounds for genes affiliated with Adrenal Gland Hyperfunction

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GO Terms for genes affiliated with Adrenal Gland Hyperfunction

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Products for genes affiliated with Adrenal Gland Hyperfunction

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Sources for Adrenal Gland Hyperfunction

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet