MCID: ADR013
MIFTS: 25

Adrenal Gland Hyperfunction malady

Rare diseases, Endocrine diseases categories

Summaries for Adrenal Gland Hyperfunction

About this section
Sources:
45NINDS, 66Wikipedia, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
NINDS:45 Cushing's syndrome, also called , is a rare endocrine disorder caused by chronic exposure of the body's tissues to excess levels of cortisol - a hormone naturally produced by the adrenal gland. Exposure to too much cortisol can occur from long-term use of synthetic glucocorticoid hormones to treat inflammatory illnesses. Pituitary adenomas (benign tumors of the pituitary gland) that secrete increased amounts of ACTH ( a substance that controls the release of cortisol) can also spur overproduction of cortisol. Tumors of the adrenal gland and ectopic ACTH syndrome (a condition in which ACTH is produced by various types of potentially malignant tumors that occur in different parts of the body) can cause similar problems with cortisol balance. Common symptoms of Cushing's syndrome include upper body obesity, severe fatigue and muscle weakness, high blood pressure, backache, elevated blood sugar, easy bruising, and bluish-red stretch marks on the skin. In women, there may be increased growth of facial and body hair, and menstrual periods may become irregular or stop completely. Neurological symptoms include difficulties with memory and neuromuscular disorders.

MalaCards: Adrenal Gland Hyperfunction, also known as hypercortisolism, is related to cushing's syndrome and hyperaldosteronism. The drugs fludrocortisone and fluorocortisol acetate have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, cortex and skin.

Wikipedia:66 Adrenocortical hyperfunction is a condition where there is an overexpression of products of the adrenal... more...

Aliases & Classifications for Adrenal Gland Hyperfunction

About this section
Sources:
9Disease Ontology, 44NIH Rare Diseases, 45NINDS, 46Novoseek, 63UMLS, 59SNOMED-CT, 36MeSH
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Endocrine diseases


Aliases & Descriptions:

adrenal gland hyperfunction 9 44 63
hypercortisolism 9 45 46
hyperadrenalism 9 44
disorder of corticoadrenal overactivity 9
adrenocortical hyperfunction 9
overproduction of cortisol 9


External Ids:

Disease Ontology9 DOID:3947
MeSH36 D000308

Related Diseases for Adrenal Gland Hyperfunction

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Graphical network of the top 20 diseases related to Adrenal Gland Hyperfunction:



Diseases related to adrenal gland hyperfunction

Symptoms for Adrenal Gland Hyperfunction

About this section

Drugs & Therapeutics for Adrenal Gland Hyperfunction

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Adrenal Gland Hyperfunction

Drug clinical trials:

Search ClinicalTrials for Adrenal Gland Hyperfunction

Search NIH Clinical Center for Adrenal Gland Hyperfunction

Search CenterWatch for Adrenal Gland Hyperfunction

Inferred drug relations via UMLS63/NDF-RT42:

Genetic Tests for Adrenal Gland Hyperfunction

About this section

Anatomical Context for Adrenal Gland Hyperfunction

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Adrenal Gland Hyperfunction:

34
Adrenal gland, Cortex, Skin, Adrenal cortex, Pituitary

Animal Models for Adrenal Gland Hyperfunction or affiliated genes

About this section

Publications for Adrenal Gland Hyperfunction

About this section

Variations for Adrenal Gland Hyperfunction

About this section

Expression for genes affiliated with Adrenal Gland Hyperfunction

About this section
Sources:
16Gene Expression Omnibus DataSets
See all sources

Search GEO for disease gene expression data for Adrenal Gland Hyperfunction.

Pathways for genes affiliated with Adrenal Gland Hyperfunction

About this section

Compounds for genes affiliated with Adrenal Gland Hyperfunction

About this section

GO Terms for genes affiliated with Adrenal Gland Hyperfunction

About this section

Products for genes affiliated with Adrenal Gland Hyperfunction

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Adrenal Gland Hyperfunction

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet