MCID: ADL080
MIFTS: 22

Adult Acute Respiratory Distress Syndrome

Categories: Respiratory diseases, Rare diseases, Cardiovascular diseases

Aliases & Classifications for Adult Acute Respiratory Distress Syndrome

MalaCards integrated aliases for Adult Acute Respiratory Distress Syndrome:

Name: Adult Acute Respiratory Distress Syndrome 56
Adult Ards 56

Characteristics:

Orphanet epidemiological data:

56
adult acute respiratory distress syndrome
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: Adult;

Classifications:

Orphanet: 56  
Rare respiratory diseases


External Ids:

Orphanet 56 ORPHA70578
ICD10 via Orphanet 34 J80

Summaries for Adult Acute Respiratory Distress Syndrome

MalaCards based summary : Adult Acute Respiratory Distress Syndrome, also known as adult ards, is related to acute respiratory distress syndrome. The drugs Clonidine and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include lung, brain and testes.

Related Diseases for Adult Acute Respiratory Distress Syndrome

Diseases in the Adult Respiratory Distress Syndrome family:

Acute Respiratory Distress Syndrome Adult Acute Respiratory Distress Syndrome

Diseases related to Adult Acute Respiratory Distress Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 acute respiratory distress syndrome 10.2

Symptoms & Phenotypes for Adult Acute Respiratory Distress Syndrome

Drugs & Therapeutics for Adult Acute Respiratory Distress Syndrome

Drugs for Adult Acute Respiratory Distress Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 340)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clonidine Approved Phase 4 4205-90-7 2803
2
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
3
Midazolam Approved, Illicit Phase 4,Phase 3 59467-70-8 4192
4
Acetaminophen Approved Phase 4,Phase 2,Phase 3 103-90-2 1983
5
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
6
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-23-7 5754 657311
7
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2 378-44-9 9782
8
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
9
Budesonide Approved Phase 4,Phase 2 51333-22-3 63006 5281004
10
Remifentanil Approved Phase 4 132875-61-7 60815
11
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
12
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
13
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
14
Menthol Approved Phase 4,Phase 2 2216-51-5 16666
15
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
16
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
17
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
18
Thrombin Approved Phase 4
19 Beractant Approved Phase 4,Phase 2,Phase 3,Phase 1 108778-82-1
20 Poractant alfa Approved Phase 4,Phase 3,Phase 2 129069-19-8
21 Racepinephrine Approved Phase 4,Phase 2
22
Carbon monoxide Approved Phase 4,Phase 1 630-08-0 281
23
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-02-2 5743
24
Progesterone Approved, Vet_approved Phase 4,Phase 2,Phase 3 57-83-0 5994
25
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3 57-27-2 5288826
26
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
27
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
28
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
29
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
30 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1
31
Glycine Approved, Nutraceutical, Vet_approved Phase 4,Phase 1,Phase 2 56-40-6 750
32 Cisatracurium Experimental Phase 4,Phase 3 96946-41-7
33
Butyric Acid Experimental Phase 4,Phase 3,Phase 2 107-92-6 264
34 Nefopam Investigational Phase 4 13669-70-0
35 Sivelestat Investigational Phase 4,Phase 1,Phase 2 127373-66-4
36 Prednisolone acetate Phase 4,Phase 2,Phase 3
37 Betamethasone Valerate Phase 4,Phase 3,Phase 2 2152-44-5
38 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
39 glucocorticoids Phase 4,Phase 2,Phase 3
40
protease inhibitors Phase 4,Phase 2,Phase 3,Phase 1
41 Fibrin Tissue Adhesive Phase 4
42 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
43 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1
44 Methylprednisolone acetate Phase 4,Phase 2,Phase 3
45 Adjuvants, Anesthesia Phase 4,Phase 3
46 Methylprednisolone Hemisuccinate Phase 4,Phase 2,Phase 3
47 Mitogens Phase 4
48 Serine Proteinase Inhibitors Phase 4,Phase 2,Phase 3,Phase 1
49 GABA Agents Phase 4,Phase 3
50 GABA Modulators Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 816)

id Name Status NCT ID Phase Drugs
1 Effects of Neuromuscular Blocking Agents (NMBA) on the Alteration of Transpulmonary Pressures at the Early Phase of Acute Respiratory Distress Syndrome (ARDS) Unknown status NCT01573715 Phase 4 NIMBEX;NIMBEX
2 Effect of Treatment With Stress-Doses Glucocorticoid in Patients With Acute Respiratory Distress Syndrome (ARDS) Unknown status NCT00773058 Phase 4 hydrocortisone;placebo
3 Propofol Versus Midazolam as Premedication for Preterm Neonates With Respiratory Distress Syndrome (RDS) Unknown status NCT00797160 Phase 4 propofol
4 Efficacy Evaluation of Surfactant Administration Via Laryngeal Mask Airway Unknown status NCT01173237 Phase 4
5 Early CPAP in Respiratory Distress Syndrome Unknown status NCT00368680 Phase 4
6 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
7 Two Strategies of RDS Treatment in Newborns With Birth Weight > 1500 Grams Unknown status NCT00277030 Phase 4 Surfactant
8 FRC Guided Therapy in Acute Respiratory Failure Unknown status NCT01280019 Phase 4
9 Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure Unknown status NCT01873521 Phase 4
10 Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparations Unknown status NCT01941524 Phase 4 Poractant alfa instillation;Beractant instillation
11 The Study of Using Esophageal Pressure to Guide the PEEP Setting in Abdominal Hypertension Patients Who Undergoing Mechanical Ventilation Unknown status NCT01825304 Phase 4
12 6-Methyl-Prednisolone for Multiple Organ Dysfunction Syndrome Unknown status NCT00127985 Phase 4 6-methyl-prednisolone
13 Prevention of Chronic Lung Disease (CLD) in Preterm Infants Unknown status NCT00883532 Phase 4 budesonide;surfactant and air (placebo)
14 Withholding Feeds During Red Blood Cell Transfusion and TRAGI Unknown status NCT02132819 Phase 4
15 Hemostasis in Kocher-Langenbeck Approaches for Acetabular Surgery Using a Topical Surgical Hemostat (Vitagel) Unknown status NCT01230931 Phase 4
16 Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) Completed NCT01600651 Phase 4
17 Standard Treatment Compliance of Participants, Effectiveness and Prognosis in Acute Respiratory Distress Syndrome Completed NCT02178982 Phase 4
18 Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study) Completed NCT02166853 Phase 4 sevoflurane;midazolam
19 INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery Completed NCT01020409 Phase 4
20 Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in Japan Completed NCT00219375 Phase 4 Sivelestat sodium hydrate;Sivelestat sodium hydrate
21 Premedication for Non-Emergency Endotracheal Intubation In the NICU Completed NCT01749501 Phase 4 Rocuronium
22 Effects of Bolus Surfactant Therapy on Peripheral Perfusion Index and Tissue Carbon Monoxide Completed NCT01923844 Phase 4 exogenous surfactant
23 Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal Intubation Completed NCT01042600 Phase 4
24 Efficacy of Combining Prophylactic Curosurf With Early Nasal CPAP in Delivery Room: the Curpap Study Completed NCT00501982 Phase 4 Poractant alfa (Curosurf®)
25 Remifentanil Versus Morphine for Sedation of Premature Neonates With Respiratory Distress Syndrome Completed NCT00391105 Phase 4 Remifentanil
26 Synchronized Intermittent Mandatory Ventilation (SIMV) Versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) In Preterm Infants With Respiratory Distress Completed NCT00486850 Phase 4
27 Comparison of Effectiveness of Nasal CPAP and Nasal IMV in Early Rescue Surfactant Treatment in Preterm Infants Completed NCT01741129 Phase 4
28 Non-Positive Pressure Ventilation in Hypoxemic Patients Completed NCT00925860 Phase 4
29 Effect of Perioperative Lung Protective Strategies on the Occurrence of Postoperative Pulmonary Complications in Patients Undergoing Lumbar Spinal Surgery in the Prone Position Completed NCT02373475 Phase 4
30 Steroids in Bilateral Total Knee Replacement Completed NCT01399268 Phase 4 Hydrocortisone;Saline
31 Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach Completed NCT02135146 Phase 4 Plasmalyte 3ml/kg/hr group;Plasmalyte 6ml/kg/hr group
32 Vaginal Progesterone for Prevention of Preterm Labor in Asymptomatic Twin Pregnancies With Sonographic Short Cervix Completed NCT02338830 Phase 4 Progesterone
33 Corticosteroid Mediates Acute Respiratory Distress Syndrome Recruiting NCT02819453 Phase 4 Dexamethasone
34 Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome Recruiting NCT01731795 Phase 4 Dexamethasone
35 Impact of Fluid Resuscitation Therapy on Pulmonary Edema as Measured by Alveolar Fluid Clearance in Patients With Acute Respiratory Distress Syndrome (ARDS) Recruiting NCT01763853 Phase 4 4% albumin
36 Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrome Recruiting NCT02164734 Phase 4 remifentanil
37 Handling Oxygenation Targets in the Intensive Care Unit Recruiting NCT03174002 Phase 4 Oxygen;Oxygen
38 Early Non-invasive Ventilation Outside the Intensive Care Unit Recruiting NCT01572337 Phase 4
39 Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation Recruiting NCT03026777 Phase 4 intravenous crystalloid fluid, 500 mL
40 Pilot Study to Compare Fresh Frozen Plasma With 24-Hour Plasma in Babies Up to Age Six Months Recruiting NCT02774317 Phase 4
41 Dexmedetomidine Versus Standard Clinical Practice During Non Invasive Mechanical Ventilation Recruiting NCT02958150 Phase 4 Dexmedetomidine
42 Sleep Intervention During Acute Lung Injury Active, not recruiting NCT01050699 Phase 4 Dexmedetomidine;Midazolam and Fentanyl
43 Paediatric Ards Neuromuscular Blockade Study Not yet recruiting NCT02902055 Phase 4 Neuromuscular Blocking Agents;Isotonic saline
44 NIPPV and nBiPAP Methods in Preterm Infants With Respiratory Distress Syndrome Not yet recruiting NCT02901652 Phase 4
45 SLI MANEUVER and RESPIRATORY MORBIDITIES Not yet recruiting NCT02887924 Phase 4
46 Intratracheal Budesonide/Surfactant Prevents BPD Not yet recruiting NCT03275415 Phase 4 budesonide;Saline
47 Different Lipid Emulsions in Acute Lung Injury Patients Terminated NCT01814956 Phase 4 Lipoplus 20%;Lipofundin N 20%
48 (S5-SAMU) Randomized Study Comparing the ASV (Adaptative Support Ventilation) to Conventional Ventilation Terminated NCT02348047 Phase 4
49 Antenatal Rescue Course of Glucocorticoids in Threatened Premature Birth Terminated NCT00295464 Phase 4 Betamethasone sodium phos (drug)
50 Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants Terminated NCT00767039 Phase 4 Survanta (beractant);Curosurf (poractant)

Search NIH Clinical Center for Adult Acute Respiratory Distress Syndrome

Genetic Tests for Adult Acute Respiratory Distress Syndrome

Anatomical Context for Adult Acute Respiratory Distress Syndrome

MalaCards organs/tissues related to Adult Acute Respiratory Distress Syndrome:

39
Lung, Brain, Testes, Fetal Lung, Liver, Bone, Heart

Publications for Adult Acute Respiratory Distress Syndrome

Articles related to Adult Acute Respiratory Distress Syndrome:

id Title Authors Year
1
Outcomes and survival prediction models for severe adult acute respiratory distress syndrome treated with extracorporeal membrane oxygenation. ( 27919283 )
2016
2
Is high-frequency oscillatory ventilation more effective and safer than conventional protective ventilation in adult acute respiratory distress syndrome patients? A meta-analysis of randomized controlled trials. ( 24887179 )
2014
3
Extracorporeal membrane oxygenation in adult acute respiratory distress syndrome. ( 21742220 )
2011
4
Resolution of organ functional scores to predict the outcome in adult acute respiratory distress syndrome patients receiving high-frequency oscillatory ventilation. ( 22027886 )
2011
5
A practical approach to adult acute respiratory distress syndrome. ( 21572751 )
2010
6
High-frequency oscillatory ventilation for adult acute respiratory distress syndrome: a decade of progress. ( 15753715 )
2005
7
High-frequency oscillatory ventilation in adult acute respiratory distress syndrome. ( 12897997 )
2003
8
Prospective, randomized, controlled pilot study of partial liquid ventilation in adult acute respiratory distress syndrome. ( 11897644 )
2002
9
Has high-frequency ventilation been inappropriately discarded in adult acute respiratory distress syndrome? ( 9875923 )
1998
10
Intratracheal aerosolization of endotoxin (LPS) in the rat: a comprehensive animal model to study adult (acute) respiratory distress syndrome. ( 9202956 )
1997

Variations for Adult Acute Respiratory Distress Syndrome

Expression for Adult Acute Respiratory Distress Syndrome

Search GEO for disease gene expression data for Adult Acute Respiratory Distress Syndrome.

Pathways for Adult Acute Respiratory Distress Syndrome

GO Terms for Adult Acute Respiratory Distress Syndrome

Sources for Adult Acute Respiratory Distress Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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