MCID: ADL027
MIFTS: 41

Adult Dermatomyositis

Categories: Rare diseases, Skin diseases, Bone diseases, Nephrological diseases, Neuronal diseases, Muscle diseases

Aliases & Classifications for Adult Dermatomyositis

MalaCards integrated aliases for Adult Dermatomyositis:

Name: Adult Dermatomyositis 12 14
Adult Onset Dermatomyositis 12
Adult Type Dermatomyositis 69

Classifications:



External Ids:

Disease Ontology 12 DOID:14202
UMLS 69 C0221056

Summaries for Adult Dermatomyositis

MalaCards based summary : Adult Dermatomyositis, also known as adult onset dermatomyositis, is related to dermatomyositis and childhood type dermatomyositis. An important gene associated with Adult Dermatomyositis is MBL2 (Mannose Binding Lectin 2), and among its related pathways/superpathways are Tuberculosis and Dendritic Cells Developmental Lineage Pathway. The drugs Abatacept and Pirfenidone have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and lung.

Related Diseases for Adult Dermatomyositis

Diseases in the Dermatomyositis family:

Adult Dermatomyositis

Diseases related to Adult Dermatomyositis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
# Related Disease Score Top Affiliating Genes
1 dermatomyositis 11.6
2 childhood type dermatomyositis 11.3
3 vulvar vestibulitis syndrome 10.4 MBL2 TNF
4 listeriosis 10.4 MBL2 TNF
5 streptococcal meningitis 10.4 MBL2 TNF
6 rheumatic fever 10.3 MBL2 TNF
7 hemorrhagic fever 10.3 GPT TNF
8 rheumatic heart disease 10.3 MBL2 TNF
9 nonalcoholic steatohepatitis 10.3 GPT TNF
10 scrub typhus 10.3 GPT TNF
11 hepatitis e 10.3 GPT TNF
12 protein-energy malnutrition 10.3 GPT TNF
13 hepatitis a 10.3 GPT TNF
14 compartment syndrome 10.3 CHKB TNF
15 endometritis 10.3 CHKB TNF
16 obstructive jaundice 10.3 GPT TNF
17 hepatic encephalopathy 10.2 GPT TNF
18 alcoholic hepatitis 10.2 GPT TNF
19 cerebral palsy 10.2 MBL2 TNF
20 otitis media 10.2 MBL2 TNF
21 multidrug-resistant tuberculosis 10.2 TNF VDR
22 rosacea 10.2 TNF VDR
23 portal hypertension 10.2 GPT TNF
24 lepromatous leprosy 10.2 TNF VDR
25 cholangitis 10.2 GPT TNF
26 prostatitis 10.2 TNF VDR
27 salmonellosis 10.1 GPT VDR
28 calcinosis 10.1
29 central nervous system vasculitis 10.1 TLR9 TNF
30 coccidiosis 10.1 TLR9 TNF
31 lichen disease 10.1 TLR9 TNF
32 lacrimal apparatus disease 10.1 TLR9 TNF
33 middle ear disease 10.1 TLR9 TNF
34 perinatal necrotizing enterocolitis 10.0 TLR9 TNF
35 hypersensitivity reaction type iv disease 10.0 TLR9 TNF
36 ileitis 10.0 TLR9 TNF
37 meningococcal meningitis 10.0 MBL2 TLR9
38 extrinsic cardiomyopathy 10.0 TLR9 TNF
39 exanthem 10.0 TLR9 TNF
40 hepatitis b 10.0 GPT MBL2 TNF
41 opportunistic mycosis 10.0 TLR9 TNF
42 uterine anomalies 10.0 TLR9 TNF
43 keratoconjunctivitis sicca 10.0 TLR9 TNF
44 nose disease 10.0 TLR9 TNF
45 cryptococcosis 10.0 MBL2 TLR9
46 parasitic helminthiasis infectious disease 10.0 TLR9 TNF
47 upper respiratory tract disease 10.0 TLR9 TNF
48 leukocyte disease 10.0 TLR9 TNF
49 tonsillitis 10.0 TLR9 TNF
50 invasive aspergillosis 10.0 MBL2 TLR9

Graphical network of the top 20 diseases related to Adult Dermatomyositis:



Diseases related to Adult Dermatomyositis

Symptoms & Phenotypes for Adult Dermatomyositis

Drugs & Therapeutics for Adult Dermatomyositis

Drugs for Adult Dermatomyositis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 114)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Abatacept Approved Phase 4,Phase 3,Phase 2 332348-12-6 10237
2
Pirfenidone Approved, Investigational Phase 4 53179-13-8 40632
3 beta-endorphin Phase 4,Phase 2
4 Adrenocorticotropic Hormone Phase 4,Phase 2
5 Vaccines Phase 4
6 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
7 Hormones Phase 4,Phase 3,Phase 2,Phase 1
8 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
9 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
10 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
11 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
12 Melanocyte-Stimulating Hormones Phase 4,Phase 2
13 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1
14 Analgesics Phase 4,Phase 2,Phase 3,Phase 1
15 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3,Phase 1
16 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 2,Phase 3,Phase 1
17
Methotrexate Approved Phase 3,Phase 2 1959-05-2, 59-05-2 126941
18
Prednisolone Approved, Vet_approved Phase 3,Phase 2 50-24-8 5755
19
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2 22916-47-8 4189
20
Methylprednisolone Approved, Vet_approved Phase 3,Phase 2 83-43-2 6741
21
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
22
Levoleucovorin Approved, Investigational Phase 3,Phase 2 68538-85-2
23
Tacrolimus Approved, Investigational Phase 2, Phase 3 104987-11-3 445643 439492
24
Cyclophosphamide Approved, Investigational Phase 2, Phase 3,Phase 1 50-18-0, 6055-19-2 2907
25
Alendronate Approved Phase 2, Phase 3 121268-17-5, 66376-36-1 2088
26
Etanercept Approved, Investigational Phase 2, Phase 3,Phase 1 185243-69-0
27
rituximab Approved Phase 2, Phase 3 174722-31-7 10201696
28
Infliximab Approved Phase 2, Phase 3 170277-31-3
29
Benzocaine Approved, Investigational Phase 2, Phase 3 1994-09-7, 94-09-7 2337
30
belimumab Approved Phase 2, Phase 3 356547-88-1 5957 10451420
31
Acetylcysteine Approved, Investigational Phase 2, Phase 3 616-91-1 12035
32
leucovorin Approved, Nutraceutical Phase 3,Phase 2 58-05-9 143 6006
33
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2 59-30-3 6037
34 tannic acid Approved, Nutraceutical Phase 2, Phase 3
35 Prednisolone acetate Phase 3,Phase 2
36 glucocorticoids Phase 3,Phase 2,Phase 1
37 Methylprednisolone acetate Phase 3,Phase 2
38 Methylprednisolone Hemisuccinate Phase 3,Phase 2
39 Folic Acid Antagonists Phase 3,Phase 2
40 Gastrointestinal Agents Phase 3,Phase 2,Phase 1
41 Neuroprotective Agents Phase 3,Phase 2
42 Cyclosporins Phase 3,Phase 2
43 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
44 Dermatologic Agents Phase 3,Phase 2
45 Vitamin B Complex Phase 3,Phase 2
46 Antiemetics Phase 3,Phase 2
47 Anti-Infective Agents Phase 3,Phase 2,Phase 1
48 Antifungal Agents Phase 3,Phase 2
49 Prednisolone hemisuccinate Phase 3,Phase 2
50 Prednisolone phosphate Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 85)

# Name Status NCT ID Phase Drugs
1 Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases Unknown status NCT01151644 Phase 4
2 Immune Response After Human Papillomavirus Vaccination in Patients With Autoimmune Disease Completed NCT00815282 Phase 4
3 Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of Dermatomyositis Recruiting NCT02245841 Phase 4 H.P. Acthar Gel
4 Abatacept in Juvenile Dermatomyositis Recruiting NCT02594735 Phase 4 Abatacept
5 MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study Active, not recruiting NCT03226119 Phase 4
6 Pirfenidone in Progressive Interstitial Lung Disease Associated With Clinically Amyopathic Dermatomyositis Not yet recruiting NCT02821689 Phase 4 Pirfenidone
7 Five-year Actively Controlled Clinical Trial in New Onset Juvenile Dermatomyositis Unknown status NCT00323960 Phase 3 3 MPDN pulse + PDN;3 MPDN pulse + PDN + CSA;3 MPDN pulse + PDN + MTX
8 Efficacy and Safety Study of GB-0998 for Treatment of Steroid-resistant Polymyositis and Dermatomyositis (PM/DM) Completed NCT00335985 Phase 3 GB-0998;Placebo of GB-0998
9 Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM Completed NCT00651040 Phase 3 Prednisone;Methotrexate
10 Investigation in Myositis-associated Pneumonitis of Prednisolone And Concomitant Tacrolimus Completed NCT00504348 Phase 2, Phase 3 Tacrolimus
11 Alendronate Osteoporosis Study Completed NCT00277251 Phase 2, Phase 3 Alendronate
12 Anakinra in Myositis Completed NCT01165008 Phase 2, Phase 3 Anakinra
13 Treatment With TNF Blockade, Infliximab, in Patients With Myositis Completed NCT00443222 Phase 2, Phase 3 Infliximab
14 Study Evaluating Efficacy and Safety of Octagam 10% in Patients With Dermatomyositis (Idiopathic Inflammatory Myopathy) Recruiting NCT02728752 Phase 3 Octagam 10%
15 Rituximab Versus Cyclophosphamide in Connective Tissue Disease-ILD Recruiting NCT01862926 Phase 2, Phase 3 Rituximab;Cyclophosphamide
16 Trial to Evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory Myopathy Recruiting NCT02971683 Phase 3 Abatacept subcutaneous;Placebo
17 Belimumab in Myositis Recruiting NCT02347891 Phase 2, Phase 3 Belimumab;Placebo
18 Understanding the Pathogenesis and Treatment of Childhood Onset Dermatomyositis Terminated NCT00035958 Phase 2, Phase 3 Prednisone;Methotrexate;Etanercept
19 A Clinical Trial for CTD-ILD Treatment Terminated NCT01424033 Phase 2, Phase 3 N-Acetylcysteine
20 Abatacept Treatment in Polymyositis and Dermatomyositis Unknown status NCT01315938 Phase 2 Abatacept;Abatacept
21 Acthar in Treatment of Refractory Dermatomyositis and Polymyositis Completed NCT01906372 Phase 2 Adrenocorticotropic Hormone Gel
22 Topical Sodium Thiosulfate and Fractional Carbon Dioxide Laser in Treating Dermatomyositis Associated Calcinosis Completed NCT01572844 Phase 2 Sodium thiosulfate
23 Safety and Efficacy of BAF312 in Dermatomyositis Completed NCT02029274 Phase 2 BAF312 0.5 mg;BAF312 2 mg;BAF312 10 mg;Placebo to BAF312
24 Safety and Effectiveness of h5G1.1-mAb for Dermatomyositis Completed NCT00005571 Phase 2 h5G1.1-mAb
25 Efficacy of an Individual Rehabilitation Program in Polymyositis and Dermatomyositis Completed NCT01415219 Phase 2
26 Methimazole to Treat Polymyositis and Dermatomyositis Completed NCT00001421 Phase 2 methimazole
27 Infliximab (Remicade ) to Treat Dermatomyositis and Polymyositis Completed NCT00033891 Phase 2 Infliximab
28 Absorption of Corticosteroids in Children With Juvenile Dermatomyositis Completed NCT00004357 Phase 2 Methylprednisolone;Prednisolone
29 Rituximab for the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM) Completed NCT00106184 Phase 2 Rituximab;Placebo
30 Intravenousimmunoglobulin (IVIg) for the Treatment of Inflammatory Myopathies Completed NCT00001261 Phase 2 Gamma Globulin
31 A Study to Evaluate the Long-Term Safety of MEDI-545 in Adult Participants With Systemic Lupus Erythematosus or Myositis Completed NCT00979654 Phase 2 Sifalimumab
32 Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis Recruiting NCT03267277 Phase 2 Sodium Thiosulfate
33 Study of IFN-K in Dermatomyositis Recruiting NCT02980198 Phase 2
34 A Study In Adults With Moderate To Severe Dermatomyositis Recruiting NCT03181893 Phase 2 PF-06823859;Placebo Arm
35 Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis Recruiting NCT02043548 Phase 2 tocilizumab;placebo
36 Trial of IMO-8400 in Adult Patients With Dermatomyositis Active, not recruiting NCT02612857 Phase 2 IMO-8400 Dose Group 1;IMO-8400 Dose Group 2;Placebo
37 Safety, Tolerability, and Efficacy of JBT-101 in Subjects With Dermatomyositis Active, not recruiting NCT02466243 Phase 2 JBT-101;Placebo;JBT-101 Open-label
38 Basiliximab Treating Interstitial Pneumonia of CADM Not yet recruiting NCT03192657 Phase 2 Basiliximab;Calcineurin Inhibitors;Steroids
39 Denosumab for Glucocorticoid-treated Children With Rheumatic Disorders Not yet recruiting NCT02418273 Phase 1, Phase 2 denosumab
40 Efficacy and Tolerability of BAF312 in Patients With Polymyositis and Dermatomyositis Terminated NCT01148810 Phase 2 BAF312;Placebo
41 A Pilot Study to Evaluate Topical Sodium Thiosulfate Therapy for Calcinosis Cutis Withdrawn NCT01918904 Phase 2 Sodium thiosulfate;Placebo
42 Evaluation of the Safety and Effectiveness of Tailored Transoral Incisionless Fundoplication (TIF) Using EsophyX for the Treatment of GERD Withdrawn NCT01025739 Phase 2
43 A Pilot Study of Etanercept in Dermatomyositis Completed NCT00112385 Phase 1 Etanercept;Placebo
44 A Study to Evaluate Safety of Multi-Dose MEDI-545 in Adult Patients With Dermatomyositis or Polymyositis Completed NCT00533091 Phase 1
45 A Phase 1 Study of MEDI7734 in Type I Interferon-Mediated Autoimmune Diseases Completed NCT02780674 Phase 1
46 Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders Completed NCT00010335 Phase 1
47 Mycophenolate Mofetil in Systemic Sclerosis Completed NCT00433186 Phase 1 Mycophenolate Mofetil
48 Study of Tofacitinib in Refractory Dermatomyositis Recruiting NCT03002649 Phase 1 Tofacitinib
49 Dermatomyositis and Polymyositis Registry Unknown status NCT01637064 Acthar
50 Creatine Supplementation in Pediatric Rheumatology Unknown status NCT01217320

Search NIH Clinical Center for Adult Dermatomyositis

Genetic Tests for Adult Dermatomyositis

Anatomical Context for Adult Dermatomyositis

MalaCards organs/tissues related to Adult Dermatomyositis:

38
Bone, Skin, Lung, Heart, Eye, Colon

Publications for Adult Dermatomyositis

Articles related to Adult Dermatomyositis:

(show top 50) (show all 81)
# Title Authors Year
1
Abatacept in the treatment of adult dermatomyositis and polymyositis: a randomised, phase IIb treatment delayed-start trial. ( 28993346 )
2018
2
Gene Expression Profiling in Blood and Affected Muscle Tissues Reveals Differential Activation Pathways in Patients with New-onset Juvenile and Adult Dermatomyositis. ( 27803134 )
2017
3
Environmental factors associated with disease flare in juvenile and adult dermatomyositis. ( 28444299 )
2017
4
2016 ACR-EULAR adult dermatomyositis and polymyositis and juvenile dermatomyositis response criteria-methodological aspects. ( 28977549 )
2017
5
The cutaneous and systemic findings associated with nuclear matrix protein-2 antibodies in adult dermatomyositis patients. ( 28129490 )
2017
6
Extensive calcinosis in adult dermatomyositis. ( 28396153 )
2017
7
2016 American College of Rheumatology/European League Against Rheumatism criteria for minimal, moderate, and major clinical response in adult dermatomyositis and polymyositis: An International Myositis Assessment and Clinical Studies Group/Paediatric Rheumatology International Trials Organisation Collaborative Initiative. ( 28385805 )
2017
8
Liposteroid therapy for juvenile and adult dermatomyositis: efficacy and side effects. ( 28361075 )
2017
9
2016 American College of Rheumatology/European League Against Rheumatism Criteria for Minimal, Moderate, and Major Clinical Response in Adult Dermatomyositis and Polymyositis: An International Myositis Assessment and Clinical Studies Group/Paediatric Rheumatology International Trials Organisation Collaborative Initiative. ( 28382787 )
2017
10
Association of vitamin D receptor gene BsmI B/b and FokI F/f polymorphisms with adult dermatomyositis and systemic lupus erythematosus. ( 26972080 )
2016
11
Anti-TIF1-I^-positive young adult dermatomyositis with germ cell tumour. ( 27457276 )
2016
12
Adult dermatomyositis associated with benign ovarian teratoma: A case report. ( 27073526 )
2016
13
Differential roles of hypoxia and innate immunity in juvenile and adult dermatomyositis. ( 27121733 )
2016
14
Colonic vasculopathy and perforation in the initial presentation of adult dermatomyositis in a patient with improving muscle weakness. ( 26759443 )
2016
15
Universalis Calcinosis in Adult Dermatomyositis: An "Anti-NXP2 Syndrome". ( 27660942 )
2016
16
Clinico pathological study of adult dermatomyositis: Importance of muscle histology in the diagnosis. ( 26019418 )
2015
17
Gastrointestinal endarteropathy in adult dermatomyositis. ( 26184526 )
2015
18
Severe adult dermatomyositis with unusual calcinosis. ( 26286744 )
2015
19
A case of adult dermatomyositis with calcinosis universalis. ( 25400376 )
2014
20
HLA class II alleles may influence susceptibility to adult dermatomyositis and polymyositis in a Han Chinese population. ( 24894810 )
2014
21
Adult dermatomyositis with bleeding ulcer in the pharynx. ( 25328739 )
2014
22
IL-1RN VNTR Polymorphism in Adult Dermatomyositis and Systemic Lupus Erythematosus. ( 25328514 )
2014
23
Focal lipodystrophy without metabolic disorders in adult dermatomyositis. ( 22804743 )
2013
24
MBL2 polymorphisms - manifestations in bulgarian patients with adult dermatomyositis and systemic lupus erythematosus. ( 24103065 )
2013
25
Adult dermatomyositis associated with lipodystrophy. ( 23962582 )
2013
26
A case of adult dermatomyositis associated with parainfluenza virus infection and Jo-1 antibody. ( 24341326 )
2013
27
Therapy of calcinosis universalis complicating adult dermatomyositis. ( 24131911 )
2013
28
Renal cell carcinoma-associated adult dermatomyositis treated laparoscopic nephrectomy. ( 24311917 )
2013
29
Analysis of metabolic syndrome in adult dermatomyositis with a focus on cardiovascular disease. ( 23139205 )
2013
30
Lacy reticular-pattern calcinosis in adult dermatomyositis. ( 23908532 )
2013
31
Adult dermatomyositis: experience of a Brazilian tertiary care center. ( 23223700 )
2012
32
Association of TNF-I+ polymorphisms with adult dermatomyositis and systemic lupus erythematosus in Bulgarian patients. ( 22913362 )
2012
33
Marked improvement of calcinosis in adult dermatomyositis with etidronate therapy. ( 21710176 )
2012
34
Changes in novel biomarkers of disease activity in juvenile and adult dermatomyositis are sensitive biomarkers of disease course. ( 22886447 )
2012
35
Clinical features, pathogenesis and treatment of juvenile and adult dermatomyositis. ( 21947177 )
2011
36
Adult dermatomyositis with severe polyneuropathy: does neuromyositis exist? ( 20229079 )
2010
37
An extremely severe case of cutaneous calcinosis complicating adult dermatomyositis. ( 19076816 )
2009
38
Clinical characteristics and outcomes of juvenile and adult dermatomyositis. ( 19654958 )
2009
39
Calcinosis cutis: a rare feature of adult dermatomyositis. ( 18319027 )
2008
40
Tracheoesophageal fistula: a rare complication of adult dermatomyositis. ( 18474474 )
2008
41
Case of pneumatosis cystoides intestinalis in adult dermatomyositis. ( 18181780 )
2008
42
Lipodystrophy and metabolic abnormalities in a case of adult dermatomyositis. ( 17938031 )
2007
43
Acute-onset adult dermatomyositis presenting with erythroderma and diplopia. ( 17868397 )
2007
44
Difference in adhesion molecule expression (ICAM-1 and VCAM-1) in juvenile and adult dermatomyositis, polymyositis and inclusion body myositis. ( 16431335 )
2006
45
Severe gastrointestinal inflammation in adult dermatomyositis: characterization of a novel clinical association. ( 17170621 )
2006
46
Clinical significance of von Willebrand factor in patients with adult dermatomyositis. ( 15565394 )
2005
47
Regression of cutis calcinosis with diltiazem in adult dermatomyositis. ( 15757822 )
2005
48
Disease course, frequency of relapses and survival of 73 patients with juvenile or adult dermatomyositis. ( 15789887 )
2005
49
Pruritus in adult dermatomyositis. ( 15115510 )
2004
50
Digital infarcts showing microangiopathy in adult dermatomyositis suggest severe pulmonary involvement and poor prognosis. ( 15214917 )
2004

Variations for Adult Dermatomyositis

Expression for Adult Dermatomyositis

Search GEO for disease gene expression data for Adult Dermatomyositis.

Pathways for Adult Dermatomyositis

Pathways related to Adult Dermatomyositis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.38 TLR9 TNF VDR
2 11.27 TLR9 TNF
3 11.19 TLR9 TNF
4 11.01 TLR9 TNF
5 10.91 TNF VDR
6 10.7 TLR9 TNF
7 9.77 TNF VDR

GO Terms for Adult Dermatomyositis

Biological processes related to Adult Dermatomyositis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.65 TLR9 TNF VDR
2 positive regulation of JNK cascade GO:0046330 9.49 TLR9 TNF
3 positive regulation of interleukin-6 production GO:0032755 9.46 TLR9 TNF
4 positive regulation of JUN kinase activity GO:0043507 9.43 TLR9 TNF
5 defense response to bacterium GO:0042742 9.43 MBL2 TLR9 TNF
6 positive regulation of phagocytosis GO:0050766 9.4 MBL2 TNF
7 positive regulation of interleukin-8 production GO:0032757 9.37 TLR9 TNF
8 negative regulation of interleukin-6 production GO:0032715 9.32 TLR9 TNF
9 positive regulation of NF-kappaB import into nucleus GO:0042346 9.16 TLR9 TNF
10 positive regulation of chemokine production GO:0032722 8.96 TLR9 TNF
11 negative regulation of growth of symbiont in host GO:0044130 8.62 MBL2 TNF

Sources for Adult Dermatomyositis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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