MCID: ADL010
MIFTS: 60

Adult Respiratory Distress Syndrome

Categories: Respiratory diseases, Cardiovascular diseases, Rare diseases

Aliases & Classifications for Adult Respiratory Distress Syndrome

MalaCards integrated aliases for Adult Respiratory Distress Syndrome:

Name: Adult Respiratory Distress Syndrome 38 12 14
Respiratory Distress Syndrome, Adult 42 69
Non-Cardiogenic Pulmonary Edema 12 69
Shock Lung 12
Adult Rds 12
Ards 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11394
ICD10 33 J80
MeSH 42 D012128
NCIt 47 C3353
UMLS 69 C0035222

Summaries for Adult Respiratory Distress Syndrome

Disease Ontology : 12 A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.

MalaCards based summary : Adult Respiratory Distress Syndrome, also known as respiratory distress syndrome, adult, is related to toxoplasmosis and lymphoma, and has symptoms including cheyne-stokes respiration, coughing and dyspnea. An important gene associated with Adult Respiratory Distress Syndrome is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Allograft rejection and Toll-like Receptor Signaling Pathway. The drugs Midazolam and Propofol have been mentioned in the context of this disorder. Affiliated tissues include Lung and Lung, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and growth/size/body region

Related Diseases for Adult Respiratory Distress Syndrome

Diseases in the Adult Respiratory Distress Syndrome family:

Acute Respiratory Distress Syndrome Adult Acute Respiratory Distress Syndrome

Diseases related to Adult Respiratory Distress Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 326)
id Related Disease Score Top Affiliating Genes
1 toxoplasmosis 30.4 IL6 TNF
2 lymphoma 29.9 ACE IL10 IL6 TNF
3 goodpasture syndrome 29.4 C4A CXCL8 IL10 IL6 TNF
4 pyelonephritis 29.1 ACE CXCL8 F2 IL10 TNF
5 malaria 28.8 ANGPT2 CXCL8 IL10 IL6 TNF
6 myocardial infarction 28.0 ACE F2 IL10 IL6 SERPINE1 TNF
7 acute respiratory distress syndrome 11.8
8 oculomotor nerve paralysis 10.7 CXCL8 IL6
9 pure autonomic failure 10.7 IL10 TNF
10 common peroneal nerve lesion 10.7 CXCL8 IL6
11 smarca4-deficient sarcoma of thorax 10.7 IL6 TNF
12 chronic orthostatic intolerance 10.7 ELANE ELN
13 papular elastorrhexis 10.7 ELANE ELN
14 acute ackee fruit intoxication 10.7 IL10 TNF
15 lymphangiectasia, intestinal 10.7 C4A CXCL8 ELANE
16 aortic arch interruption 10.7 IL6 TNF
17 lymph node palisaded myofibroblastoma 10.7 CXCL8 IL10
18 anal fistula 10.7 CXCL8 ELANE ELN
19 halal setton wang syndrome 10.6 CXCL8 TF TNF
20 multiple familial trichoepithelioma 10.6 IL10 TNF
21 congenital insensitivity to pain with hyperhidrosis 10.6 CXCL8 IL10
22 tetanus 10.6 ELANE ELN TNF
23 cryptogenic late-onset epileptic spasms 10.6 ACE TNF
24 lagophthalmos 10.6 IL10 TNF
25 pyridoxal 5'-phosphate-dependent epilepsy 10.6 ELANE TNF
26 cardiac sarcoidosis 10.6 ACE TNF
27 type 1 papillary adenoma of the kidney 10.6 IL10 TNF
28 hidradenitis suppurativa 10.6 CXCL8 IL10
29 peroneal nerve paralysis 10.6 IL10 IL6
30 spirillary rat-bite fever 10.6 CXCL8 IL6 TNF
31 pasteurellosis 10.6 CXCL8 IL6 TNF
32 hemangioma of orbit 10.6 ELANE TNF
33 cicatricial lagophthalmos 10.6 CXCL8 IL6 TNF
34 basidiobolomycosis 10.6 CXCL8 IL10 TNF
35 nasal cavity carcinoma in situ 10.6 CXCL8 ELANE TNF
36 acquired thrombocytopenia 10.6 CXCL8 IL6 TNF
37 myeloid sarcoma 10.5 CXCL8 IL6 TNF
38 esophagus leiomyoma 10.5 CXCL8 IL6 TNF
39 tarsal tunnel syndrome 10.5 CXCL8 IL10 TNF
40 plantar wart 10.5 CXCL8 IL10 TNF
41 breast disease 10.5 CXCL8 IL6 TNF
42 drug rash with eosinophilia and systemic symptoms 10.5 CXCL8 IL10 IL6
43 neuromuscular disease 10.5 ACE TNF
44 senile reticular retinal degeneration 10.5 CXCL8 IL10 TNF
45 infancy electroclinical syndrome 10.5 CXCL8 IL10 IL6
46 legionellosis 10.5 CXCL8 IL6 TNF
47 endosalpingiosis 10.5 IL10 TNF
48 bladder sarcoma 10.5 IL6 TF TNF
49 spondylolysis 10.5 CXCL8 IL6 TNF
50 myofascial pain syndrome 10.5 CXCL8 IL10 IL6

Graphical network of the top 20 diseases related to Adult Respiratory Distress Syndrome:



Diseases related to Adult Respiratory Distress Syndrome

Symptoms & Phenotypes for Adult Respiratory Distress Syndrome

UMLS symptoms related to Adult Respiratory Distress Syndrome:


cheyne-stokes respiration, coughing, dyspnea, hemoptysis, hoarseness, respiratory distress, labored breathing

GenomeRNAi Phenotypes related to Adult Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.7 ACE CXCL8 F2 IL10 SERPINB2 TNF
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.7 ACE CXCL8 F2 IL10 SERPINB2 TNF

MGI Mouse Phenotypes related to Adult Respiratory Distress Syndrome:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.1 ACE C5 F2 IL10 IL6 SERPINB2
2 cardiovascular system MP:0005385 10.09 ACE ANGPT2 C5 F2 IL10 IL6
3 homeostasis/metabolism MP:0005376 10.06 TF TNF SERPINB2 SERPINE1 ACE ANGPT2
4 hematopoietic system MP:0005397 10.02 ACE ELANE F2 IL10 IL6 SERPINB2
5 immune system MP:0005387 10 ACE ANGPT2 C5 ELANE F2 IL10
6 mortality/aging MP:0010768 9.93 ACE ANGPT2 C5 ELANE F2 IL10
7 neoplasm MP:0002006 9.5 ACE ELANE IL10 IL6 SERPINE1 SFTPC
8 respiratory system MP:0005388 9.23 ANGPT2 C5 F2 IL10 IL6 SERPINE1

Drugs & Therapeutics for Adult Respiratory Distress Syndrome

Drugs for Adult Respiratory Distress Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 393)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Midazolam Approved, Illicit Phase 4,Phase 3 59467-70-8 4192
2
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
3
Remifentanil Approved Phase 4 132875-61-7 60815
4
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
5
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-23-7 5754 657311
6 Racepinephrine Approved Phase 4,Phase 2
7 Beractant Approved Phase 4,Phase 2,Phase 3,Phase 1 108778-82-1
8
Budesonide Approved Phase 4,Phase 2 51333-22-3 63006 5281004
9 Poractant alfa Approved Phase 4,Phase 2,Phase 3 129069-19-8
10
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Phase 1 103-90-2 1983
11
Clonidine Approved Phase 4 4205-90-7 2803
12
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
13
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
14
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
15
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
16
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
17
Thrombin Approved Phase 4
18
Carbon monoxide Approved Phase 4,Phase 1 630-08-0 281
19
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
20
Benzocaine Approved Phase 4,Phase 2,Phase 3,Phase 1 1994-09-7, 94-09-7 2337
21
Desflurane Approved Phase 4 57041-67-5 42113
22
Ketamine Approved, Vet_approved Phase 4,Phase 3 6740-88-1 3821
23
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2 378-44-9 9782
24
Menthol Approved Phase 4,Phase 2 2216-51-5 16666
25 Povidone-iodine Approved Phase 4,Phase 3,Phase 2 25655-41-8
26
Metformin Approved Phase 4 657-24-9 14219 4091
27
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3 57-27-2 5288826
28
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
29
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
30
Progesterone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 57-83-0 5994
31
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-02-2 5743
32
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
33
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
34
Misoprostol Approved Phase 4 59122-46-2 5282381
35 tannic acid Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1
36
Glycine Approved, Nutraceutical, Vet_approved Phase 4,Phase 1,Phase 2 56-40-6 750
37 Cisatracurium Experimental Phase 4,Phase 3 96946-41-7
38
Butyric Acid Experimental Phase 4,Phase 3,Phase 2 107-92-6 264
39 Nefopam Investigational Phase 4 13669-70-0
40 Sivelestat Investigational Phase 4,Phase 1,Phase 2 127373-66-4
41 Adjuvants, Anesthesia Phase 4,Phase 3
42 Anesthetics Phase 4,Phase 3,Early Phase 1
43 Anesthetics, General Phase 4,Phase 3
44 Anesthetics, Intravenous Phase 4,Phase 3
45 Anti-Anxiety Agents Phase 4,Phase 3
46 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1
47 GABA Agents Phase 4,Phase 3
48 GABA Modulators Phase 4,Phase 3
49 Hypnotics and Sedatives Phase 4,Phase 3,Phase 2,Phase 1
50 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 1015)

id Name Status NCT ID Phase Drugs
1 Propofol Versus Midazolam as Premedication for Preterm Neonates With Respiratory Distress Syndrome (RDS) Unknown status NCT00797160 Phase 4 propofol
2 Efficacy Evaluation of Surfactant Administration Via Laryngeal Mask Airway Unknown status NCT01173237 Phase 4
3 Effects of Neuromuscular Blocking Agents (NMBA) on the Alteration of Transpulmonary Pressures at the Early Phase of Acute Respiratory Distress Syndrome (ARDS) Unknown status NCT01573715 Phase 4 NIMBEX;NIMBEX
4 Early CPAP in Respiratory Distress Syndrome Unknown status NCT00368680 Phase 4
5 Effect of Treatment With Stress-Doses Glucocorticoid in Patients With Acute Respiratory Distress Syndrome (ARDS) Unknown status NCT00773058 Phase 4 hydrocortisone;placebo
6 Two Strategies of RDS Treatment in Newborns With Birth Weight > 1500 Grams Unknown status NCT00277030 Phase 4 Surfactant
7 Prevention of Chronic Lung Disease (CLD) in Preterm Infants Unknown status NCT00883532 Phase 4 budesonide;surfactant and air (placebo)
8 Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparations Unknown status NCT01941524 Phase 4 Poractant alfa instillation;Beractant instillation
9 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
10 Surfactant Administration During Spontaneous Breathing Unknown status NCT01329432 Phase 4
11 The Study of Using Esophageal Pressure to Guide the PEEP Setting in Abdominal Hypertension Patients Who Undergoing Mechanical Ventilation Unknown status NCT01825304 Phase 4
12 6-Methyl-Prednisolone for Multiple Organ Dysfunction Syndrome Unknown status NCT00127985 Phase 4 6-methyl-prednisolone
13 Withholding Feeds During Red Blood Cell Transfusion and TRAGI Unknown status NCT02132819 Phase 4
14 Hemostasis in Kocher-Langenbeck Approaches for Acetabular Surgery Using a Topical Surgical Hemostat (Vitagel) Unknown status NCT01230931 Phase 4
15 Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure Unknown status NCT01873521 Phase 4
16 FRC Guided Therapy in Acute Respiratory Failure Unknown status NCT01280019 Phase 4
17 Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure. Unknown status NCT00331656 Phase 4
18 Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn Unknown status NCT01499238 Phase 4
19 Remifentanil Versus Morphine for Sedation of Premature Neonates With Respiratory Distress Syndrome Completed NCT00391105 Phase 4 Remifentanil
20 Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in Japan Completed NCT00219375 Phase 4 Sivelestat sodium hydrate;Sivelestat sodium hydrate
21 Standard Treatment Compliance of Participants, Effectiveness and Prognosis in Acute Respiratory Distress Syndrome Completed NCT02178982 Phase 4
22 Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) Completed NCT01600651 Phase 4
23 Effects of Bolus Surfactant Therapy on Peripheral Perfusion Index and Tissue Carbon Monoxide Completed NCT01923844 Phase 4 exogenous surfactant
24 Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal Intubation Completed NCT01042600 Phase 4
25 Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study) Completed NCT02166853 Phase 4 sevoflurane;midazolam
26 Efficacy of Combining Prophylactic Curosurf With Early Nasal CPAP in Delivery Room: the Curpap Study Completed NCT00501982 Phase 4 Poractant alfa (Curosurf®)
27 Premedication for Non-Emergency Endotracheal Intubation In the NICU Completed NCT01749501 Phase 4 Rocuronium
28 Synchronized Intermittent Mandatory Ventilation (SIMV) Versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) In Preterm Infants With Respiratory Distress Completed NCT00486850 Phase 4
29 Comparison of Effectiveness of Nasal CPAP and Nasal IMV in Early Rescue Surfactant Treatment in Preterm Infants Completed NCT01741129 Phase 4
30 INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery Completed NCT01020409 Phase 4
31 Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach Completed NCT02135146 Phase 4 Plasmalyte 3ml/kg/hr group;Plasmalyte 6ml/kg/hr group
32 Effect of Perioperative Lung Protective Strategies on the Occurrence of Postoperative Pulmonary Complications in Patients Undergoing Lumbar Spinal Surgery in the Prone Position Completed NCT02373475 Phase 4
33 Inflammatory Response Secondary Using Intravenous Anesthesia Versus Inhalation Anesthesia With Halogenated Agents Completed NCT02168751 Phase 4 propofol;Sevoflurane
34 Vaginal Progesterone for Prevention of Preterm Labor in Asymptomatic Twin Pregnancies With Sonographic Short Cervix Completed NCT02338830 Phase 4 Progesterone
35 Steroids in Bilateral Total Knee Replacement Completed NCT01399268 Phase 4 Hydrocortisone;Saline
36 Non-Positive Pressure Ventilation in Hypoxemic Patients Completed NCT00925860 Phase 4
37 Recruitment Maneuver After Intubation Completed NCT01014299 Phase 4
38 Evaluation Of The Total Face Mask For Emergency Application In Acute Respiratory Failure Completed NCT00686257 Phase 4
39 Efficacy of 17 Alpha-hydroxyprogesterones Caproate for the Prevention of Preterm Delivery Completed NCT00331695 Phase 4 17 alpha-hydroxyprogesterones caproate
40 Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates Completed NCT01403623 Phase 4
41 Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IV Completed NCT01604447 Phase 4
42 Intraoperative Protective Ventilation in Abdominal Surgery (IMPROVE Study) Completed NCT01282996 Phase 4
43 Corticosteroid Mediates Acute Respiratory Distress Syndrome Recruiting NCT02819453 Phase 4 Dexamethasone
44 Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome Recruiting NCT01731795 Phase 4 Dexamethasone
45 Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrome Recruiting NCT02164734 Phase 4 remifentanil
46 Impact of Fluid Resuscitation Therapy on Pulmonary Edema as Measured by Alveolar Fluid Clearance in Patients With Acute Respiratory Distress Syndrome (ARDS) Recruiting NCT01763853 Phase 4 4% albumin
47 Effect Of Ketamine Infusion In Patients With COPD Applied One Lung Ventilation Recruiting NCT02962999 Phase 4 Ketamine;Saline
48 Effect of Antenatal Steroid on Pulmonary Artery Blood Flow Recruiting NCT02978976 Phase 4 Betamethasone;saline
49 Handling Oxygenation Targets in the Intensive Care Unit Recruiting NCT03174002 Phase 4 Oxygen;Oxygen
50 Early Non-invasive Ventilation Outside the Intensive Care Unit Recruiting NCT01572337 Phase 4

Search NIH Clinical Center for Adult Respiratory Distress Syndrome

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: respiratory distress syndrome, adult

Genetic Tests for Adult Respiratory Distress Syndrome

Anatomical Context for Adult Respiratory Distress Syndrome

MalaCards organs/tissues related to Adult Respiratory Distress Syndrome:

39
Lung, Brain, Testes, Liver, Fetal Lung, Neutrophil, Cervix
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Adult Respiratory Distress Syndrome:
id Tissue Anatomical CompartmentCell Relevance
1 Lung Alveoli Alveolar Epithelial Type 1 Cells Potential therapeutic candidate, affected by disease
2 Lung Alveoli Alveolar Epithelial Type 2 Cells Potential therapeutic candidate, affected by disease
3 Lung Pulmonary Capillary Plexus Affected by disease

Publications for Adult Respiratory Distress Syndrome

Articles related to Adult Respiratory Distress Syndrome:

(show top 50) (show all 578)
id Title Authors Year
1
Extracorporeal membrane oxygenation in the management of post-pneumonectomy air leak and adult respiratory distress syndrome of the non-operated lung. ( 28132594 )
2017
2
Incidence of adult respiratory distress syndrome in trauma patients: A systematic review and meta-analysis over a period of three decades. ( 28590348 )
2017
3
Extracorporeal membrane oxygenation for adult respiratory distress syndrome in trauma patients: A case series and systematic literature review. ( 27779577 )
2017
4
Neurologic Injury With Severe Adult Respiratory Distress Syndrome in Patients Undergoing Extracorporeal Membrane Oxygenation: A Single-Center Retrospective Analysis. ( 28863024 )
2017
5
History of adult respiratory distress syndrome. ( 27155768 )
2016
6
Validity of Outcome Prediction Scoring Systems in Korean Patients with Severe Adult Respiratory Distress Syndrome Receiving Extracorporeal Membrane Oxygenation Therapy. ( 27247503 )
2016
7
A Case of Scrub Typhus Complicated by Adult Respiratory Distress Syndrome and Successful Management with Extracorporeal Membrane Oxygenation. ( 27458040 )
2016
8
Adult respiratory distress syndrome. ( 27513791 )
2016
9
Performance of Multiple Risk Assessment Tools to Predict Mortality for Adult Respiratory Distress Syndrome with Extracorporeal Membrane Oxygenation Therapy: An External Validation Study Based on Chinese Single-center Data. ( 27411456 )
2016
10
Coronavirus NL63-induced Adult Respiratory Distress Syndrome. ( 26720790 )
2016
11
H1N1 with adult respiratory distress syndrome for emergency lower segment cesarean section: A case report. ( 27375404 )
2016
12
Ambulatory Extracorporeal Membrane Oxygenation: A Surgical Innovation for Adult Respiratory Distress Syndrome. ( 26963436 )
2016
13
Early initiation of extracorporeal membrane oxygenation improves survival in adult trauma patients with severe adult respiratory distress syndrome. ( 27032012 )
2016
14
High tidal volume decreases adult respiratory distress syndrome, atelectasis, and ventilator days compared with low tidal volume in pediatric burned patients with inhalation injury. ( 25724604 )
2015
15
A case of tension pneumothorax during hyperbaric oxygen therapy in an earthquake survivor with crush injury complicated by ARDS (adult respiratory distress syndrome). ( 26094299 )
2015
16
External validation of scores proposed for estimation of survival probability of patients with severe adult respiratory distress syndrome undergoing extracorporeal membrane oxygenation therapy: a retrospective study. ( 25887616 )
2015
17
Near drowning and adult respiratory distress syndrome. ( 25453852 )
2015
18
Boussignac CPAP system for brain death confirmation with apneic test in case of acute lung injury/adult respiratory distress syndrome - series of cases. ( 26124664 )
2015
19
Rapid-onset adult respiratory distress syndrome after activated charcoal aspiration. A pitch-black tale of a potential to kill. ( 25635491 )
2015
20
Severe adult respiratory distress syndrome from Goodpasture syndrome. Survival using extracorporeal membrane oxygenation. ( 25590156 )
2015
21
Arthritis and adult respiratory distress syndrome: unusual presentations of typhoid fever. ( 25336548 )
2014
22
Surgical lung biopsy in adult respiratory distress syndrome: a meta-analysis. ( 25069683 )
2014
23
High-frequency oscillation in early adult respiratory distress syndrome. ( 25041589 )
2014
24
Comparing surrogates of oxygenation and ventilation between airway pressure release ventilation and biphasic airway pressure in a mechanical model of adult respiratory distress syndrome. ( 24998370 )
2014
25
Ventilation during extracorporeal membrane oxygenation for adult respiratory distress syndrome. ( 25041935 )
2014
26
Adult respiratory distress syndrome risk factors for injured patients undergoing damage-control laparotomy: AAST multicenter post hoc analysis. ( 25248057 )
2014
27
Near drowning and adult respiratory distress syndrome. ( 24642043 )
2014
28
Adult respiratory distress syndrome following cardiac surgery. ( 24299028 )
2014
29
Surgical lung biopsy to diagnose Behcet's vasculitis with adult respiratory distress syndrome. ( 25378849 )
2014
30
Blood alcohol content, injury severity, and adult respiratory distress syndrome. ( 24854314 )
2014
31
The Role of Corticosteroids in Adult Respiratory Distress Syndrome caused by Viridans Group Streptococci Bacteremia in Neutropenic Patients. ( 25237468 )
2014
32
Adult respiratory distress syndrome induced by blunt trauma-A dying threat throughout the world? ( 24398078 )
2013
33
Hitch-hiker taken for a ride: an unusual cause of myocarditis, septic shock and adult respiratory distress syndrome. ( 23314875 )
2013
34
Risk stratification in critically ill patients: GDF-15 scores in adult respiratory distress syndrome. ( 23905849 )
2013
35
High or conventional positive end-expiratory pressure in adult respiratory distress syndrome. ( 24290732 )
2013
36
The Adult Respiratory Distress Syndrome Cognitive Outcomes Study: long-term neuropsychological function in survivors of acute lung injury. ( 23714655 )
2013
37
Odontogenic infection leading to adult respiratory distress syndrome. ( 22871306 )
2013
38
A case of vivax malaria complicated by adult respiratory distress syndrome and successful management with extracorporeal membrane oxygenation. ( 24327781 )
2013
39
Paracrine activity of stem cells in therapy for acute lung injury and adult respiratory distress syndrome. ( 23609289 )
2013
40
Mortality of patients with respiratory insufficiency and adult respiratory distress syndrome after surgery: the obesity paradox. ( 21778465 )
2012
41
The adult respiratory distress syndrome cognitive outcomes study: long-term neuropsychological function in survivors of acute lung injury. ( 22492988 )
2012
42
Unmasking of tracheomalacia following short-term mechanical ventilation in a patient of adult respiratory distress syndrome. ( 22701211 )
2012
43
Fresh frozen plasma/red blood cell resuscitation regimen that restores procoagulants without causing adult respiratory distress syndrome. ( 22491592 )
2012
44
The effect of hypoxia-hypercapnia on neuropsychological function in adult respiratory distress syndrome. ( 23250501 )
2012
45
An innovative approach to predict the development of adult respiratory distress syndrome in patients with blunt trauma. ( 22914080 )
2012
46
Trends in caring for adult respiratory distress syndrome patients. ( 22475700 )
2012
47
Aseptic meningitis and adult respiratory distress syndrome caused by Borrelia persica. ( 22782695 )
2012
48
A retrospective exploration of patient-ventilator monitoring intensity, therapeutic intervention intensity, and compliance with lung protective guidelines in a cohort of patients with adult respiratory distress syndrome. ( 20180828 )
2011
49
Adult respiratory distress syndrome caused by 2009 H1N1 influenza during pregnancy: success of ECMO for both the mother and the child. ( 21848176 )
2011
50
A surge of flu-associated adult respiratory distress syndrome in an Austrian tertiary care hospital during the 2009/2010 Influenza A H1N1v pandemic. ( 21465083 )
2011

Variations for Adult Respiratory Distress Syndrome

Expression for Adult Respiratory Distress Syndrome

Search GEO for disease gene expression data for Adult Respiratory Distress Syndrome.

Pathways for Adult Respiratory Distress Syndrome

Pathways related to Adult Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

(show all 31)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.74 C4A C5 CXCL8 IL10 IL6 TNF
2
Show member pathways
12.69 ACE CXCL8 IL10 IL6 SERPINE1 TNF
3
Show member pathways
12.53 ANGPT2 F2 IL10 IL6 TNF
4
Show member pathways
12.09 CXCL8 IL10 IL6 TNF
5 11.94 C5 CXCL8 IL6 TNF
6 11.91 CXCL8 IL10 IL6 TNF
7 11.89 IL10 IL6 TNF
8 11.86 CXCL8 IL6 SERPINB2 SERPINE1
9
Show member pathways
11.85 IL10 IL6 TNF
10 11.85 C4A CXCL8 IL10 IL6 TF TNF
11 11.81 CXCL8 IL6 SERPINE1 TNF
12 11.8 C4A C5 F2 SERPINB2 SERPINE1
13 11.79 ANGPT2 IL6 SERPINE1 TF
14 11.77 CXCL8 IL6 TNF
15 11.76 CXCL8 IL10 IL6 TNF
16 11.69 IL10 IL6 TNF
17 11.65 IL10 IL6 TNF
18
Show member pathways
11.6 CXCL8 IL6 TNF
19 11.54 C4A C5 IL10
20 11.53 CXCL8 IL6 TNF
21 11.46 ELANE IL6 TNF
22 11.36 CXCL8 IL10 IL6 TNF
23 11.31 IL10 IL6 TNF
24 11.31 CXCL8 IL10 IL6 TNF
25 11.3 IL10 IL6 TNF
26 11.22 IL10 IL6 TNF
27 11.15 CXCL8 ELN IL6 SFTPC TNF
28 11.03 ANGPT2 CXCL8 IL10 IL6 TNF
29 10.98 C4A C5 CXCL8 IL10 IL6 TNF
30 10.91 CXCL8 IL6 TNF
31 10.76 SERPINB2 SERPINE1

GO Terms for Adult Respiratory Distress Syndrome

Cellular components related to Adult Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.8 ACE ANGPT2 C4A C5 CXCL8 ELANE
2 endoplasmic reticulum lumen GO:0005788 9.56 C4A F2 IL6 TF
3 extracellular region GO:0005576 9.5 ACE ANGPT2 C4A C5 CXCL8 ELANE
4 external side of plasma membrane GO:0009897 9.46 ACE F2 IL6 TNF

Biological processes related to Adult Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

(show all 29)
id Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.85 ANGPT2 ELANE F2 TNF
2 regulation of complement activation GO:0030449 9.81 C4A C5 F2
3 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.8 IL10 IL6 TNF
4 response to glucocorticoid GO:0051384 9.73 IL10 IL6 TNF
5 positive regulation of smooth muscle cell proliferation GO:0048661 9.71 ELANE IL6 TNF
6 negative regulation of endopeptidase activity GO:0010951 9.71 C4A C5 SERPINB2 SERPINE1
7 positive regulation of angiogenesis GO:0045766 9.67 ANGPT2 C5 CXCL8 SERPINE1
8 cellular protein metabolic process GO:0044267 9.65 C4A F2 IL6 SFTPC TF
9 embryonic digestive tract development GO:0048566 9.64 CXCL8 TNF
10 positive regulation of chemokine production GO:0032722 9.64 IL6 TNF
11 cellular response to hepatocyte growth factor stimulus GO:0035729 9.62 IL10 IL6
12 positive regulation of blood coagulation GO:0030194 9.62 F2 SERPINE1
13 response to molecule of bacterial origin GO:0002237 9.61 CXCL8 IL10
14 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.61 IL10 TNF
15 neutrophil mediated immunity GO:0002446 9.6 ACE IL6
16 negative regulation of fibrinolysis GO:0051918 9.59 F2 SERPINE1
17 negative regulation of lipid storage GO:0010888 9.58 IL6 TNF
18 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.58 ELANE TNF
19 endothelial cell apoptotic process GO:0072577 9.57 IL10 TNF
20 response to yeast GO:0001878 9.52 ELANE IL6
21 negative regulation of cytokine secretion involved in immune response GO:0002740 9.51 IL10 TNF
22 fibrinolysis GO:0042730 9.5 F2 SERPINB2 SERPINE1
23 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.49 IL6 TNF
24 neutrophil mediated killing of gram-negative bacterium GO:0070945 9.48 ELANE F2
25 receptor biosynthetic process GO:0032800 9.46 IL10 TNF
26 negative regulation of chemokine biosynthetic process GO:0045079 9.43 ELANE IL6
27 inflammatory response GO:0006954 9.43 C4A C5 CXCL8 IL10 IL6 TNF
28 negative regulation of growth of symbiont in host GO:0044130 9.33 ELANE IL10 TNF
29 cellular response to lipopolysaccharide GO:0071222 9.02 CXCL8 IL10 IL6 SERPINE1 TNF

Molecular functions related to Adult Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 9.33 ELANE SERPINE1 TNF
2 cytokine activity GO:0005125 9.26 CXCL8 IL10 IL6 TNF
3 receptor binding GO:0005102 9.02 ANGPT2 C5 F2 IL6 SERPINE1

Sources for Adult Respiratory Distress Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
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36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
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59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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