MCID: AGN005
MIFTS: 24

Agenesis of the Dorsal Pancreas malady

Categories: Rare diseases, Endocrine diseases

Aliases & Classifications for Agenesis of the Dorsal Pancreas

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Aliases & Descriptions for Agenesis of the Dorsal Pancreas:

Name: Agenesis of the Dorsal Pancreas 45
Congenital Pancreatic Agenesis 45 24
Complete Agenesis of the Dorsal Pancreas 45
Partial Agenesis of the Dorsal Pancreas 45
Pancreatic Agenesis, Congenital 65
 
Pancreas, Dorsal, Agenesis of 45
Partial Pancreatic Agenesis 45
Pancreas Agenesis, Dorsal 45
Congenital Short Pancreas 45

Classifications:



External Ids:

UMLS65 C1850096

Summaries for Agenesis of the Dorsal Pancreas

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NIH Rare Diseases:45 Agenesis of the dorsal pancreas describes a congenital malformation of the pancreas in which either the entire dorsal pancreas or part of the dorsal pancreas fails to develop (complete agenesis or partial agenesis, respectively). some individuals experience no symptoms, while others may develop hyperglycemia, diabetes mellitus, bile duct obstruction, abdominal pain, pancreatitis, or other conditions. hyperglycemia has been shown to be present in approximately 50% of affected individuals. the cause of agenesis of the dorsal pancreas is currently not well understood. it may occur in individuals with no history of the condition in the family (sporadically) and in some cases, autosomal dominant or x-linked dominant inheritance has been suggested. it has also been reported to occur with very rare conditions including polysplenia and polysplenia/heterotaxy syndrome. last updated: 7/22/2011

MalaCards based summary: Agenesis of the Dorsal Pancreas, also known as congenital pancreatic agenesis, is related to pancreatic agenesis and hiv-1. An important gene associated with Agenesis of the Dorsal Pancreas is PDX1 (Pancreatic And Duodenal Homeobox 1). Affiliated tissues include pancreas, brain and lung.

Related Diseases for Agenesis of the Dorsal Pancreas

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Diseases related to Agenesis of the Dorsal Pancreas via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
idRelated DiseaseScoreTop Affiliating Genes
1pancreatic agenesis11.6
2hiv-110.2
3breast cancer10.2
4coronary artery disease10.2
5allergic rhinitis10.2
6hepatitis10.2
7leukemia10.2
8temporal lobe epilepsy10.2
9coenurosis10.2
10artery disease10.2
11estrogen-receptor negative breast cancer10.2
12tetanus10.2
13esophagitis10.2
14leiomyoma10.2
15coccidioidomycosis10.2
16thoracic aortic aneurysm10.2
17cervicitis10.2
18duodenal obstruction10.2
19retinitis10.2
20aortic aneurysm10.2
21rhinitis10.2
22leiomyomatosis10.2
23retinal detachment10.2
24oral submucous fibrosis10.2
25conjunctivitis10.2
26acquired immunodeficiency syndrome10.2
27mediastinitis10.2
28duodenitis10.2
29myeloid leukemia10.2
30benign metastasizing leiomyoma10.2
31fibrosing mediastinitis10.2
32glioma10.2
33aneurysm10.2
34hypoxia10.2

Graphical network of the top 20 diseases related to Agenesis of the Dorsal Pancreas:



Diseases related to agenesis of the dorsal pancreas

Symptoms for Agenesis of the Dorsal Pancreas

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Drugs & Therapeutics for Agenesis of the Dorsal Pancreas

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Agenesis of the Dorsal Pancreas

Genetic Tests for Agenesis of the Dorsal Pancreas

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Anatomical Context for Agenesis of the Dorsal Pancreas

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MalaCards organs/tissues related to Agenesis of the Dorsal Pancreas:

33
Pancreas, Brain, Lung, Spinal cord, Liver, Skin

Animal Models for Agenesis of the Dorsal Pancreas or affiliated genes

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Publications for Agenesis of the Dorsal Pancreas

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Articles related to Agenesis of the Dorsal Pancreas:

(show all 32)
idTitleAuthorsYear
1
Cystic Adventitial Disease of the Common Femoral Vessels : Report of 2 Cases and Literature Review. (24420055)
2014
2
A margin-of-the-day online adaptive intensity-modulated radiotherapy strategy for cervical cancer provides superior treatment accuracy compared to clinically recommended margins: a dosimetric evaluation. (23902275)
2013
3
DRD4 genotype predicts longevity in mouse and human. (23283341)
2013
4
Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation is associated with cell-type-dependent splicing of mtAspRS mRNA. (22023289)
2012
5
Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2. (22090124)
2012
6
The Skindex instruments to measure the effects of skin disease on quality of life. (22284137)
2012
7
Postpartum depression and culture: Pesado Corazon. (20551841)
2010
8
Interaction of heparin and heparin-derived oligosaccharides with synthetic peptide analogues of the heparin-binding domain of heparin/heparan sulfate-interacting protein. (19747524)
2009
9
Treatment outcomes for patients with synovial sarcoma of the head and neck. (18366285)
2008
10
Chapter 11 Monomelic amyotrophy of upper or lower limbs. (18808896)
2007
11
Nonfluent aphasia in a patient with Waldenstrom's macroglobulinemia. (17376690)
2007
12
Hypophosphatemia in living liver donors. (16549174)
2006
13
Two high throughput technologies to detect segmental aneuploidies identify new Williams-Beuren syndrome patients with atypical deletions. (15994861)
2006
14
A customised replacement for polyostotic fibrous dysplasia of the upper femur. A 51-year follow-up. (15686250)
2005
15
Review: metformin does not increase risk for lactic acidosis or increase lactate levels in type 2 diabetes. (15230555)
2004
16
Leptin measurement in urine in children and its relationship to other growth peptides in serum and urine. (12519416)
2003
17
Complement activation determines the therapeutic activity of rituximab in vivo. (12874252)
2003
18
The APOA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore. (12951359)
2003
19
Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome. (12204859)
2002
20
Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorder. (12378124)
2002
21
Hypogammaglobulinemia in lung transplant recipients. (11213067)
2001
22
Correlation of p53 protein expression with gene mutation in gall-bladder carcinomas. (9293532)
1997
23
Metabolism of apolipoprotein B-100 in a kindred with familial hypobetalipoproteinemia without a truncated form of apoB. (9101440)
1997
24
The effects of high- and medium-dose metformin therapy on cardiovascular risk factors in patients with type II diabetes. (8720537)
1996
25
Urinary albumin excretion in short children treated with recombinant human growth hormone. (8832141)
1996
26
Detection of P glycoprotein activity on normal and leukemic CD34+ cells. (7504150)
1993
27
Interaction between neurotensin and dopamine in the brain. Morphofunctional and clinical evidence. (1361114)
1992
28
Cystic teratoma of the mediastinum: demonstration of fat/fluid level. (2105009)
1990
29
Striatonigral degeneration. A case report and a review of the literature. (3061696)
1988
30
Angiodysplasia as a source of intestinal bleeding. (301707)
1977
31
Lack of TRH-induced TSH secretion in a patient with Klinefelter's syndrome: a case report. (809259)
1975
32
Fulminating purpuric meningococcemia. (14931767)
1952

Variations for Agenesis of the Dorsal Pancreas

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Clinvar genetic disease variations for Agenesis of the Dorsal Pancreas:

5
id Gene Variation Type Significance SNP ID Assembly Location
1PDX1PDX1, 1-BP DEL, 188CdeletionPathogenic

Expression for genes affiliated with Agenesis of the Dorsal Pancreas

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Search GEO for disease gene expression data for Agenesis of the Dorsal Pancreas.

Pathways for genes affiliated with Agenesis of the Dorsal Pancreas

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GO Terms for genes affiliated with Agenesis of the Dorsal Pancreas

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Sources for Agenesis of the Dorsal Pancreas

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet