Aliases & Classifications for Aggressive Periodontitis

About this section

Aggressive Periodontitis, Aliases & Descriptions:

Name: Aggressive Periodontitis 9 11
Periodontitis, Juvenile 60
 
Periodontitis Juvenile 43
Juvenile Periodontitis 9


External Ids:

Disease Ontology9 DOID:1474
SNOMED-CT55 49965002, 2624008
MeSH33 D010520

Summaries for Aggressive Periodontitis

About this section


Disease Ontology:9 A periodontitis that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as dental plaque and dental calculus resulting in inflammation and a loss of periodontium.

MalaCards based summary: Aggressive Periodontitis, also known as periodontitis, juvenile, is related to periodontitis and gingivitis. An important gene associated with Aggressive Periodontitis is FCGR3B (Fc fragment of IgG, low affinity IIIb, receptor (CD16b)), and among its related pathways are Fc-GammaR Pathway and Tuberculosis. The compounds tositumomab and ibritumomab have been mentioned in the context of this disorder. Affiliated tissues include bone, neutrophil and monocytes, and related mouse phenotypes are hematopoietic system and immune system.

Wikipedia:63 Aggressive periodontitis describes a type of periodontal disease and includes two of the seven... more...

Related Diseases for Aggressive Periodontitis

About this section

Graphical network of the top 20 diseases related to Aggressive Periodontitis:



Diseases related to aggressive periodontitis

Symptoms for Aggressive Periodontitis

About this section

Drugs & Therapeutics for Aggressive Periodontitis

About this section

Drug clinical trials:

Search ClinicalTrials for Aggressive Periodontitis

Search NIH Clinical Center for Aggressive Periodontitis

Genetic Tests for Aggressive Periodontitis

About this section

Anatomical Context for Aggressive Periodontitis

About this section

MalaCards organs/tissues related to Aggressive Periodontitis:

31
Bone, Neutrophil, Monocytes, Whole blood, Colon, T cells

Animal Models for Aggressive Periodontitis or affiliated genes

About this section

MGI Mouse Phenotypes related to Aggressive Periodontitis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.9FPR1, IL1A, FCER1A, FCGR2A, CYBA
2MP:00053876.7FPR1, DEFB1, CYBA, FCGR2A, FCER1A, MMP8

Publications for Aggressive Periodontitis

About this section

Articles related to Aggressive Periodontitis:

(show top 50)    (show all 485)
idTitleAuthorsYear
1
Clinical Case Report on Treatment of Generalized Aggressive Periodontitis: 5-Year Follow-up. (25909527)
2015
2
Replication of the association of GLT6D1 with aggressive periodontitis in a Sudanese population. (25682733)
2015
3
The novel role of HtrA1 in gingivitis, chronic and aggressive periodontitis. (24979214)
2014
4
Investigation of dental pulp stem cells isolated from discarded human teeth extracted due to aggressive periodontitis. (25172527)
2014
5
Clinical and Microbiological Effects of Photodynamic Therapy Associated with Non-surgical Treatment in Aggressive Periodontitis. (25346834)
2014
6
Correlation of Aggregatibacter actinomycetemcomitans Detection with Clinical/Immunoinflammatory Profile of Localized Aggressive Periodontitis Using a 16S rRNA Microarray Method: A Cross-Sectional Study. (24376864)
2013
7
Bimaxillary unilateral gingival fibromatosis with localized aggressive periodontitis (eating the tooth at the same table). (24124307)
2013
8
Aggressive periodontitis diagnosed during or before orthodontic treatment. (23210838)
2013
9
Template-guided flapless implant insertion and prosthetic rehabilitation with telescopic crowns in a patient with treated generalized aggressive periodontitis: a case report. (22299117)
2012
10
Generalized aggressive periodontitis and its treatment options: case reports and review of the literature. (22291715)
2012
11
Microbiological characterization in children with aggressive periodontitis. (22863892)
2012
12
Treatment of generalised aggressive periodontitis: a 4-year follow-up case report. (22866285)
2012
13
A combination of clinical and microbiological management of generalized aggressive periodontitis in primary teeth. A case report. (22066568)
2012
14
Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: microbiological profile. (21399951)
2012
15
Detection of human herpes viruses in patients with chronic and aggressive periodontitis and relationship between viruses and clinical parameters. (22923891)
2012
16
Prevalence of Aggregatibacter actinomycetemcomitans in Sudanese patients with aggressive periodontitis: a case-control study. (21332472)
2011
17
Report of a case of Turner's syndrome with localized aggressive periodontitis. (21976844)
2011
18
Genetic study of families affected with aggressive periodontitis. (21501238)
2011
19
The clinical assessment of aggressive periodontitis patients. (21811690)
2011
20
Local inflammatory markers and systemic endotoxin in aggressive periodontitis. (21730256)
2011
21
Volumetric analysis of intrabony defects in aggressive periodontitis patients following use of a novel composite alloplast: a pilot study. (21519556)
2011
22
Amoxicillin and metronidazole as an adjunctive treatment in generalized aggressive periodontitis at initial therapy or re-treatment: a randomized controlled clinical trial. (21062335)
2011
23
Response of chronic and aggressive periodontitis to treatment. (20403111)
2010
24
Genetic power of a Brazilian three-generation family with generalized aggressive periodontitis. (20640360)
2010
25
IL-1 gene cluster is not linked to aggressive periodontitis. (20335539)
2010
26
Eosinophilic granuloma or aggressive periodontitis?]. (20074763)
2010
27
Histopathological features of chronic and aggressive periodontitis. (20403104)
2010
28
Immunologic and microbiologic profiles of chronic and aggressive periodontitis subjects. (20450404)
2010
29
Unusual gingival enlargement with aggressive periodontitis: a case report. (20461324)
2010
30
FBAT analysis of polymorphisms of vitamin D receptor (Taq I and Fok I) in aggressive periodontitis families]. (20140038)
2010
31
Aggressive periodontitis and chronic arthritis: blood mononuclear cell gene expression and plasma protein levels of cytokines and cytokine inhibitors. (19186969)
2009
32
Ceruloplasmin induces polymorphonuclear leukocyte priming in localized aggressive periodontitis. (19656030)
2009
33
Relationship of neutrophil phagocytosis and oxidative burst with the subgingival microbiota of generalized aggressive periodontitis. (19239639)
2009
34
Risk of aggressive periodontitis in adolescent carriers of the JP2 clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans in Morocco: a prospective longitudinal cohort study. (18207019)
2008
35
Interleukin-1 and tumor necrosis factor-alpha gene polymorphisms in Turkish patients with localized aggressive periodontitis. (18587204)
2008
36
Association of vitamin D receptor gene polymorphisms in Chinese patients with generalized aggressive periodontitis. (18205735)
2008
37
Platelet-rich plasma in combination with bovine derived xenograft in the treatment of generalized aggressive periodontitis: a case report with re-entry. (17957570)
2007
38
Aggregatibacter actinomycetemcomitans as indicator for aggressive periodontitis by two analysing strategies. (17433043)
2007
39
Timing affects the clinical outcome of adjunctive systemic antibiotic therapy for generalized aggressive periodontitis. (17608574)
2007
40
Demographic, clinical, and microbial aspects of chronic and aggressive periodontitis in Colombia: a multicenter study. (17397309)
2007
41
Incomplete adherence to an adjunctive systemic antibiotic regimen decreases clinical outcomes in generalized aggressive periodontitis patients: a pilot retrospective study. (17711478)
2007
42
Expressions of selected adhesion molecules on peripheral blood leukocytes in patients with aggressive periodontitis. (15995587)
2005
43
Cytokine profile in gingival crevicular fluid of aggressive periodontitis: influence of smoking and stress. (15367195)
2004
44
The -308 polymorphism in the promoter region of the tumor necrosis factor-alpha (TNF-alpha) gene and ex vivo lipopolysaccharide-induced TNF-alpha expression in patients with aggressive periodontitis and/or type 1 diabetes mellitus. (15627647)
2004
45
Aggressive periodontitis of the primary dentition associated with idiopathic immune deficiency: case report and treatment considerations. (15554399)
2004
46
Clinical and radiographic evaluation of Emdogain as a regenerative material in the treatment of interproximal vertical defects in chronic and aggressive periodontitis patients. (15119889)
2004
47
Identification of mRNAs for the various diacylglycerol kinase isoforms in neutrophils from patients with localized aggressive periodontitis. (12941073)
2003
48
Distribution of periodontal pathogens in Korean aggressive periodontitis. (14584866)
2003
49
Lactoferrin iron levels are reduced in saliva of patients with localized aggressive periodontitis. (12083535)
2002
50
Differential gene expression in neutrophils from patients with generalized aggressive periodontitis. (11762875)
2001

Variations for Aggressive Periodontitis

About this section

Expression for genes affiliated with Aggressive Periodontitis

About this section
Search GEO for disease gene expression data for Aggressive Periodontitis.

Pathways for genes affiliated with Aggressive Periodontitis

About this section

Compounds for genes affiliated with Aggressive Periodontitis

About this section

Compounds related to Aggressive Periodontitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idCompoundScoreTop Affiliating Genes
1tositumomab49 1211.1FCGR2A, FCGR3B
2ibritumomab49 1211.1FCGR3B, FCGR2A
3alefacept43 1211.1FCGR3B, FCGR2A
4bevacizumab49 1211.1FCGR3B, FCGR2A
5efalizumab43 1211.1FCGR2A, FCGR3B
6cytochalasin b4310.1FPR1, FCGR3B
7daclizumab43 1211.1FCGR2A, FCGR3B
8basiliximab43 1211.1FCGR3B, FCGR2A
9natalizumab43 1211.1FCGR2A, FCGR3B
10alemtuzumab43 1211.1FCGR2A, FCGR3B
11gemtuzumab ozogamicin49 43 1212.1FCGR3B, FCGR2A
12adalimumab43 49 1212.1FCGR3B, FCGR2A
13ciprofloxacin43 49 1212.1IL1A, DEFB1
14abciximab43 1211.0FCGR3B, FCGR2A
15polymyxin b4310.0IL1A, DEFB1
16cetuximab43 49 1212.0FCGR3B, FCGR2A
17etanercept43 49 1212.0FCGR2A, FCGR3B
18pentoxifylline43 1210.9FPR1, IL1A
19leukotriene b443 59 2411.9FPR1, IL1A, FCGR3B
20ivig439.9IL1A, FCGR2A
21trastuzumab43 49 1211.8FCGR3B, FCGR2A
22rantes439.8DEFB1, IL1A, FPR1
23rituximab43 49 1211.7FCGR2A, FCGR3B
24hocl439.7MMP8, CYBA
25phosphoinositide439.7FCGR2A, FCGR3B, FPR1
26fluvastatin43 49 28 1212.6IL1A, CYBA
27mannose439.6FCAR, FCGR3B, FCGR2A
28dbc-amp439.6FPR1, FCGR3B
29tetracycline43 1210.4IL1A, MMP8
30fmlp439.4FCGR2A, FCGR3B, IL1A, FPR1
31n-formylmethionyl-leucylphenylalanine439.4FPR1, IL1A, FCGR3B, CYBA
32cyclosporin a43 28 5911.3FPR1, IL1A, MMP8
33nadph43 2410.3CYBA, FCGR2A, FCGR3B, FPR1
34pge2439.3FPR1, IL1A, MMP8
35glutamine439.3CYBA, FCGR2A, IL1A
36genistein43 28 59 2 24 1214.3FPR1, IL1A, MMP8, FCGR3B
37dexamethasone43 49 28 1212.2FPR1, IL1A, CYBA, DEFB1
38arachidonic acid43 28 24 1212.2CYBA, FCGR2A, IL1A, FPR1
39heparin43 28 24 1212.2FPR1, IL1A, FCGR2A
40histamine43 28 2411.2FCGR2A, FCER1A, FPR1
41retinoic acid43 2410.1FPR1, IL1A, MMP8, DEFB1
42nitric oxide43 24 1210.9FPR1, IL1A, MMP8, CYBA
43oligonucleotide438.9CYBA, FCGR2A, MMP8, FPR1
44tyrosine438.7CYBA, FCGR2A, FCGR3B, FCAR, FPR1
45lipid438.7CYBA, FCGR2A, FCGR3B, MMP8, FPR1
46superoxide43 249.6CYBA, FCGR3B, FCAR, MMP8, FPR1
47oxygen43 249.5CYBA, FCGR2A, FCAR, MMP8, FPR1
48calcium43 49 24 1211.3DMP1, CYBA, FCGR2A, FCGR3B, MMP8, FPR1
49h2o2438.3CYBA, FCGR2A, FCGR3B, MMP8, IL1A, FPR1
50serine438.3FCGR2A, FCGR3B, FCAR, MMP8, IL1A, FPR1

GO Terms for genes affiliated with Aggressive Periodontitis

About this section

Cellular components related to Aggressive Periodontitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.9IL1A, MMP8, FCAR, FCGR3B, DMP1, DEFB1

Biological processes related to Aggressive Periodontitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1immune responseGO:00069558.6IL1A, FCAR, FCGR3B, DEFB1
2innate immune responseGO:00450878.3FCER1A, FCGR2A, CYBA, DEFB1

Molecular functions related to Aggressive Periodontitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1IgG bindingGO:00198649.7FCGR3B, FCGR2A

Products for genes affiliated with Aggressive Periodontitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Aggressive Periodontitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet