MCID: ADS004
MIFTS: 38

Aids Dementia Complex

Categories: Rare diseases, Mental diseases

Aliases & Classifications for Aids Dementia Complex

MalaCards integrated aliases for Aids Dementia Complex:

Name: Aids Dementia Complex 50 52 69
Aids Related Cognitive Impairment 50
Adc 50

Classifications:



Summaries for Aids Dementia Complex

MalaCards based summary : Aids Dementia Complex, also known as aids related cognitive impairment, is related to aids - neurological complications and leukoencephalopathy with ataxia. An important gene associated with Aids Dementia Complex is CXCL12 (C-X-C Motif Chemokine Ligand 12), and among its related pathways/superpathways are Akt Signaling and PAK Pathway. The drugs Darunavir and Ritonavir have been mentioned in the context of this disorder. Affiliated tissues include brain, monocytes and testes, and related phenotypes are cellular and hematopoietic system

Related Diseases for Aids Dementia Complex

Diseases related to Aids Dementia Complex via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
id Related Disease Score Top Affiliating Genes
1 aids - neurological complications 10.9
2 leukoencephalopathy with ataxia 10.9
3 dementia 10.8
4 spondylocostal dysostosis 4 10.4 B2M TNF
5 hypogonadotropism 10.3 B2M TNF
6 primary biliary cirrhosis 10.3 B2M TNF
7 hiv-1 10.3
8 hepadnavirus infection 10.3 B2M TNF
9 steatorrhea 10.3 B2M TNF
10 oropharyngeal cancer, childhood 10.3 CCR3 TNF
11 plummer's disease 10.2 B2M TNF
12 gastroduodenal crohn's disease 10.2 CCR3 TNF
13 retinitis pigmentosa 10.2 CXCL12 TNF
14 mixed lacrimal gland cancer 10.2 B2M TNF
15 renal fibrosis 10.2 CXCL12 TNF
16 scabies 10.1 B2M TNF
17 spontaneous ocular nystagmus 10.1 CCR3 TNF
18 calcinosis 10.1 B2M TNF
19 encephalopathy 10.0
20 hepatitis b 10.0 B2M TNF
21 neuronitis 10.0
22 glossopharyngeal nerve paralysis 9.9 B2M TNF
23 ischemic optic neuropathy 9.9 CXCL12 CXCR4
24 sarcoma 9.9
25 cerebritis 9.9
26 whim syndrome 9.9 CXCL12 CXCR4
27 metabolic acidosis 9.9 CXCL12 CXCR4
28 chronic cervicitis 9.8 CXCL12 CXCR4
29 central nervous system vasculitis 9.8 CXCL12 CXCR4
30 human herpesvirus 8 9.8
31 acquired immunodeficiency syndrome 9.8
32 acute necrotizing encephalopathy type 1 9.8 CCR3 CXCR4
33 acral lentiginous melanoma 9.8 B2M ITIH4 TNF
34 rem sleep behavior disorder 9.8 CXCL12 CXCR4
35 schizophrenia 9.7
36 brain injury 9.7
37 hydrocephalus 9.7
38 traumatic brain injury 9.7
39 dystonia 9.7
40 cocaine abuse 9.7
41 chronic fatigue syndrome 9.7
42 encephalitis 9.7
43 toxoplasmosis 9.7
44 cerebral atrophy 9.7
45 myoclonus 9.7
46 ovarian brenner tumor 9.5 CXCL12 CXCR4 TNF
47 smoking as a quantitative trait locus 1 9.4 B2M CXCL12 CXCR4
48 cranioectodermal dysplasia 1 9.4 CXCL12 CXCR4 TNF
49 carotid artery dissection 9.4 CXCR4 ITIH4 TNF
50 chronic myocardial ischemia 9.2 B2M CXCL12 CXCR4

Graphical network of the top 20 diseases related to Aids Dementia Complex:



Diseases related to Aids Dementia Complex

Symptoms & Phenotypes for Aids Dementia Complex

MGI Mouse Phenotypes related to Aids Dementia Complex:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.8 B2M CCR3 CXCL12 CXCR4 ITIH4 TNF
2 hematopoietic system MP:0005397 9.65 B2M CCR3 CXCL12 CXCR4 TNF
3 immune system MP:0005387 9.55 CXCR4 TNF B2M CCR3 CXCL12
4 liver/biliary system MP:0005370 9.26 B2M CXCL12 ITIH4 TNF
5 neoplasm MP:0002006 8.92 B2M CXCR4 ITIH4 TNF

Drugs & Therapeutics for Aids Dementia Complex

Drugs for Aids Dementia Complex (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 115)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Darunavir Approved Phase 4,Phase 2,Phase 3 635728-49-3, 206361-99-1 213039
2
Ritonavir Approved, Investigational Phase 4,Phase 2,Phase 3 155213-67-5 392622
3
Lopinavir Approved Phase 4,Phase 2,Phase 3 192725-17-0 92727
4
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
5
Formaldehyde Approved, Vet_approved Phase 4 50-00-0 712
6 Racepinephrine Approved Phase 4
7
Cobicistat Approved Phase 4 1004316-88-4
8 Anti-HIV Agents Phase 4,Phase 3,Phase 2,Phase 1
9 Pharmaceutical Solutions Phase 4,Phase 2,Phase 1
10 Antimetabolites Phase 4,Phase 3,Phase 2,Phase 1
11 Calcium, Dietary Phase 4,Phase 1
12 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
13 Anti-Retroviral Agents Phase 4,Phase 3,Phase 2,Phase 1
14 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1
15 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 2,Phase 3
16 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2,Phase 3
17 HIV Protease Inhibitors Phase 4,Phase 2,Phase 3,Phase 1
18
protease inhibitors Phase 4,Phase 2,Phase 3,Phase 1
19 Epinephryl borate Phase 4
20 Vasoconstrictor Agents Phase 4
21 Anticholesteremic Agents Phase 4
22 Atorvastatin Calcium Phase 4 134523-03-8
23 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
24 Hypolipidemic Agents Phase 4
25 Lipid Regulating Agents Phase 4
26
Dopamine Approved Phase 3,Phase 2 51-61-6, 62-31-7 681
27
Methylphenidate Approved, Investigational Phase 3 113-45-1 4158
28
Zidovudine Approved Phase 3,Phase 2,Phase 1 30516-87-1 35370
29
Stavudine Approved, Investigational Phase 3 3056-17-5 18283
30
Abacavir Approved, Investigational Phase 3,Phase 2 136470-78-5 65140 441300
31
Amprenavir Approved Phase 2, Phase 3 161814-49-9 65016
32
Delavirdine Approved Phase 2, Phase 3 136817-59-9 5625
33
Efavirenz Approved, Investigational Phase 2, Phase 3 154598-52-4 64139
34
Emtricitabine Approved, Investigational Phase 2, Phase 3 143491-57-0 60877
35
Enfuvirtide Approved, Investigational Phase 2, Phase 3 159519-65-0 16130199
36
Etravirine Approved Phase 2, Phase 3 269055-15-4 193962
37
Fosamprenavir Approved Phase 2, Phase 3 226700-79-4 131536
38
Lamivudine Approved, Investigational Phase 2, Phase 3,Phase 1 134678-17-4 60825
39
Maraviroc Approved, Investigational Phase 2, Phase 3 376348-65-1 3002977
40
Nelfinavir Approved Phase 2, Phase 3 159989-64-7 64143
41
Nevirapine Approved Phase 2, Phase 3 129618-40-2 4463
42
Saquinavir Approved, Investigational Phase 2, Phase 3 127779-20-8 60787
43
Tipranavir Approved, Investigational Phase 2, Phase 3 174484-41-4 65027
44 Central Nervous System Stimulants Phase 3
45 Dopamine Agents Phase 3,Phase 2
46 Dopamine Uptake Inhibitors Phase 3
47 Neurotransmitter Agents Phase 3,Phase 2
48 Neurotransmitter Uptake Inhibitors Phase 3
49 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2,Phase 1
50 Reverse Transcriptase Inhibitors Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show all 40)

id Name Status NCT ID Phase Drugs
1 SOLFAMU Study of Nasal Brushing Collected OLFActory MUcosa Samples in the Diagnosis of Human Encephalopathies Recruiting NCT02951559 Phase 4
2 Modulation of Monocyte Activation by Atorvastatin in HIV Infection Active, not recruiting NCT01263938 Phase 4 Atorvastatin
3 Downmodulating Monocyte Activation for HIV-1 Associated Neurocognitive Disorders (HAND) Active, not recruiting NCT01600170 Phase 4 Atorvastatin (generic Lipitor);placebo
4 Effect of Cobicistat Versus Ritonavir Boosting on the Brain Permeation of Darunavir in HIV-infected Individuals Terminated NCT02503462 Phase 4 Darunavir;ritonavir;cobicistat
5 HIV - Monotherapy in Switzerland (MOST-ch) Terminated NCT00531986 Phase 4 Lopinavir-Monotherapy;HAART
6 A Study Comparing Long-acting Methylphenidate (ConcertaTM) vs. Placebo in the Treatment of Memory Loss Due to HIV Unknown status NCT01599975 Phase 3 Long acting methylphenidate;Long acting methylphenidate;Matched placebo
7 A Multicenter Placebo-Controlled Double-Blind Trial to Evaluate Azidothymidine (AZT) Treatment of the AIDS Dementia Complex and Central Nervous System (CNS) Human Immunodeficiency Virus (HIV) Infection Completed NCT00000702 Phase 3 Zidovudine
8 An Open Trial of Zidovudine (AZT) Treatment of the AIDS Dementia Complex in Patients With AIDS or Low CD4+ Lymphocyte Counts Completed NCT00000709 Phase 3 Zidovudine
9 A Study to Evaluate the Use of Stavudine (d4T) to Treat AIDS Dementia Complex Completed NCT00002246 Phase 3 Stavudine
10 A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex Completed NCT00002163 Phase 3 Abacavir sulfate
11 Clinical Trial of CNS-targeted HAART (CIT2) Completed NCT00624195 Phase 2, Phase 3 FDA Approved Antiretroviral Therapy (see list below)
12 Maraviroc and NeuroAIDS Pathogenesis Recruiting NCT02159027 Phase 2, Phase 3 Maraviroc;Placebo
13 Safety and Effectiveness of Giving CPI-1189 to HIV-Infected Patients With AIDS Dementia Unknown status NCT00002414 Phase 2 CPI-1189
14 Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia Complex Completed NCT00000657 Phase 2 Zidovudine;Didanosine
15 A Study to Evaluate the Use of Memantine In Combination With Anti-HIV Drugs to Treat AIDS Dementia Complex (ADC) Completed NCT00000867 Phase 2 Memantine
16 Ferumoxytol-enhanced Imaging and Mapping in neuroAIDS Completed NCT02678767 Phase 2 Ferumoxytol
17 Effect of Cenicriviroc on HIV Neurocognitive Impairment Completed NCT02128828 Phase 2 cenicriviroc
18 A Study of Thioctic Acid and Deprenyl in HIV-Infected Patients With Dementia Completed NCT00002154 Phase 2 Thioctic acid;Selegiline hydrochloride
19 Safety and Effectiveness of the Selegiline "Patch" for Decreased Mental Function in HIV Patients Completed NCT00013585 Phase 2 Selegiline hydrochloride
20 Intranasal Insulin for the Treatment of HAND Recruiting NCT03081117 Phase 1, Phase 2 Insulin, intranasal;Placebo, intranasal
21 Minocycline for HIV+ Cognitive Impairment in Uganda Terminated NCT00855062 Phase 1, Phase 2 minocycline;minocycline placebo capsule
22 Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1 Completed NCT00000738 Phase 1 Nimodipine;Zidovudine
23 Safety and Effectiveness of CPI-1189 in HIV-Infected Males on Combination Anti-HIV Drug Therapy Completed NCT00002209 Phase 1 CPI-1189
24 Parallel Group, Placebo-Controlled, Tolerability, Safety, and Efficacy Study of OPC-14117 in HIV Dementia Completed NCT00002148 Phase 1 OPC 14117
25 Ferumoxytol-enhanced Brain MRI in HIV-associated Neurocognitive Disorders Completed NCT01665846 Phase 1 Ferumoxytol
26 A Prospective Observational Trial to Determine Cardiovascular Diseases in HIV-infected Patients Unknown status NCT02291081
27 A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular Diseases Completed NCT00002044 Zidovudine
28 HIV-1 Specific Immune Responses in Thai Individuals With HIV Dementia Completed NCT00777426
29 A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced Disease Completed NCT00002033 Zidovudine;AS-101
30 The Prevalence of Neurocognitive Disorder in a Primary Care-based HIV Cohort Compared to a HIV-negative Control Cohort - Completed NCT01434563
31 A Study of Decreased Mental Function Associated With HIV Completed NCT00027040 Selegiline hydrochloride
32 Neurocognitive Impairment and Psychiatric Comorbidities in HIV-1 Completed NCT00476671
33 Evaluation of the Role of OCT in the Detection of HIV-associated Neurocognitive Disorder Recruiting NCT02431091
34 Mental Ability Challenge Study in Adults With and Without HIV Recruiting NCT03244488 Scopolamine Injectable Product;Mecamylamine Pill
35 Individualized Cognitive Training in HIV Recruiting NCT03122288
36 Positron Emission Tomography (PET) Imaging of Glial Activation in Psychotic Disease States Active, not recruiting NCT03257592
37 Prevalence and Predictors of Neurocognitive Impairment Among HIV-infected Patients Active, not recruiting NCT00893815
38 Mild Neurocognitive Disorder in HIV Infection of the Brain Terminated NCT01547754
39 PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD) Terminated NCT00459693 [11C]PBR28
40 Efficacy of Neuro-HAART in Patients With HIV Terminated NCT01434654

Search NIH Clinical Center for Aids Dementia Complex

Genetic Tests for Aids Dementia Complex

Anatomical Context for Aids Dementia Complex

MalaCards organs/tissues related to Aids Dementia Complex:

39
Brain, Monocytes, Testes, T Cells, Cortex

Publications for Aids Dementia Complex

Articles related to Aids Dementia Complex:

(show top 50) (show all 188)
id Title Authors Year
1
Development and in vivo evaluation of an implantable nano-enabled multipolymeric scaffold for the management of AIDS dementia complex (ADC). ( 26456249 )
2015
2
Effects of HIV-1 tat on secretion of TNF-I+ and IL-1I^ by U87 cells in AIDS patients with or without AIDS dementia complex. ( 24625401 )
2014
3
CNS toxoplasmosis induced hydrocephalus revisited and a brief review of AIDS dementia complex. ( 23749026 )
2013
4
What's in a name? AIDS dementia complex, HIV-associated dementia, HIV-associated neurocognitive disorder or HIV encephalopathy. ( 22722724 )
2012
5
HIV-1B gp120 genes from one patient with AIDS dementia complex can affect the secretion of tumor necrosis factor and interleukin 1I^ in glial cells. ( 22340390 )
2011
6
Formulation development and in vitro evaluation of didanosine-loaded nanostructured lipid carriers for the potential treatment of AIDS dementia complex. ( 20923388 )
2011
7
Memantine for AIDS dementia complex: open-label report of ACTG 301. ( 20400412 )
2010
8
High level HIV-1 DNA concentrations in brain tissues differentiate patients with post-HAART AIDS dementia complex or cardiovascular disease from those with AIDS. ( 19641870 )
2009
9
[Analysis of genetic diversity and biological functional site of HIV-1 gp120 from a patient with AIDS dementia complex]. ( 19634757 )
2009
10
Validity of the CogState brief battery: relationship to standardized tests and sensitivity to cognitive impairment in mild traumatic brain injury, schizophrenia, and AIDS dementia complex. ( 19395350 )
2009
11
Adjunctive therapies for AIDS dementia complex. ( 18646159 )
2008
12
Communication impairment in the AIDS dementia complex (ADC): a case report. ( 18242630 )
2008
13
Prevalence of AIDS dementia complex: results from a statewide population-based registry of Alzheimer's disease and related disorders. ( 19058735 )
2008
14
AIDS dementia complex in China. ( 17070055 )
2007
15
AIDS dementia complex. ( 18808977 )
2007
16
Cerebrospinal fluid markers in central nervous system HIV infection and AIDS dementia complex. ( 18808988 )
2007
17
Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity. ( 17827413 )
2007
18
SV40 and HIV sequences in the cerebrospinal fluid of a patient with AIDS dementia complex. ( 17504176 )
2007
19
AIDS dementia complex and Hashimoto encephalopathy in a senescent woman. ( 18033678 )
2007
20
Elevated cerebrospinal fluid neurofilament light protein concentrations predict the development of AIDS dementia complex. ( 17492593 )
2007
21
Factors in AIDS dementia complex trial design: results and lessons from the abacavir trial. ( 17401456 )
2007
22
The assessment of cognitive function in advanced HIV-1 infection and AIDS dementia complex using a new computerised cognitive test battery. ( 16343841 )
2006
23
AIDS dementia complex. ( 16909695 )
2006
24
Timed Gait test: normative data for the assessment of the AIDS dementia complex. ( 16840235 )
2006
25
Editorial comment: AIDS dementia complex in the current era. ( 17152650 )
2006
26
HAART & the molecular biology of AIDS dementia complex. ( 15817943 )
2005
27
Quinolinic acid selectively induces apoptosis of human astrocytes: potential role in AIDS dementia complex. ( 16042813 )
2005
28
Involvement of quinolinic acid in AIDS dementia complex. ( 15639803 )
2005
29
The AIDS dementia complex: clinical and basic neuroscience with implications for novel molecular therapies. ( 16260383 )
2005
30
CSF amyloid beta42 and tau levels correlate with AIDS dementia complex. ( 16275845 )
2005
31
Inflammation and neuroaxonal injury in multiple sclerosis and AIDS dementia complex: implications for neuroprotective treatment. ( 16138246 )
2005
32
Undetectable cerebrospinal fluid HIV RNA and beta-2 microglobulin do not indicate inactive AIDS dementia complex in highly active antiretroviral therapy-treated patients. ( 16010165 )
2005
33
Chemokine receptors, neural progenitor cells, and the AIDS dementia complex. ( 15216453 )
2004
34
Olfactory deficits in HIV-infected patients with and without AIDS dementia complex. ( 14984801 )
2004
35
Regional patterns of brain metabolites in AIDS dementia complex. ( 15528093 )
2004
36
Evidence for a change in AIDS dementia complex in the era of highly active antiretroviral therapy and the possibility of new forms of AIDS dementia complex. ( 15075501 )
2004
37
The urokinase receptor is overexpressed in the AIDS dementia complex and other neurological manifestations. ( 15122709 )
2004
38
A multi-center 1H MRS study of the AIDS dementia complex: validation and preliminary analysis. ( 12766890 )
2003
39
Cytokines and AIDS dementia complex. ( 12478083 )
2003
40
SDF-1alpha is expressed in astrocytes and neurons in the AIDS dementia complex: an in vivo and in vitro study. ( 12834106 )
2003
41
Screening for the AIDS dementia complex. ( 11862659 )
2002
42
Involvement of dopamine in the progression of AIDS Dementia Complex. ( 11956960 )
2002
43
Clinical aspects of the AIDS dementia complex in relation to histopathological and immunohistochemical variables. ( 11914551 )
2002
44
Kaposi's sarcoma and human herpesvirus 8 infection do not protect HIV-1 infected homosexual men from AIDS dementia complex. ( 11684936 )
2001
45
Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS dementia complex (ADC): evidence for neurotropic HIV variants. ( 11162807 )
2001
46
HIV-1 reverse transcriptase sequence in plasma and cerebrospinal fluid of patients with AIDS dementia complex treated with Abacavir. ( 11371689 )
2001
47
Transforming growth factor beta-1 and interferon-alpha in the AIDS dementia complex (ADC): possible relationship with cerebral viral load? ( 11282546 )
2001
48
Elevated levels of soluble Fas and Fas ligand in cerebrospinal fluid of patients with AIDS dementia complex. ( 11240032 )
2001
49
Markers of AIDS dementia complex: the role of cerebrospinal fluid assays. ( 11579253 )
2001
50
Cerebrospinal fluid S-100beta and its relationship with AIDS dementia complex. ( 11564589 )
2001

Variations for Aids Dementia Complex

Expression for Aids Dementia Complex

Search GEO for disease gene expression data for Aids Dementia Complex.

Pathways for Aids Dementia Complex

Pathways related to Aids Dementia Complex according to GeneCards Suite gene sharing:

(show all 16)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.96 CCR3 CXCL12 CXCR4 TNF
2
Show member pathways
12.77 CCR3 CXCL12 CXCR4 TNF
3
Show member pathways
12.49 CCR3 CXCL12 CXCR4
4
Show member pathways
12.46 CXCL12 CXCR4 TNF
5
Show member pathways
12.3 B2M CXCL12 CXCR4 TNF
6 11.53 CXCL12 TNF
7 11.49 CXCL12 TNF
8
Show member pathways
11.42 CCR3 CXCL12 CXCR4
9 11.42 B2M CXCL12 CXCR4 TNF
10 11.38 CXCL12 CXCR4
11 11.29 CXCL12 CXCR4
12 11.26 CCR3 TNF
13
Show member pathways
11.22 B2M TNF
14 11.05 CXCL12 CXCR4
15 10.81 CXCL12 CXCR4
16 9.91 CXCL12 TNF

GO Terms for Aids Dementia Complex

Cellular components related to Aids Dementia Complex according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.43 B2M CCR3 CXCL12 CXCR4 ITIH4 TNF
2 cell surface GO:0009986 9.33 B2M CXCR4 TNF
3 external side of plasma membrane GO:0009897 8.8 B2M CXCL12 TNF

Biological processes related to Aids Dementia Complex according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.58 B2M CXCL12 TNF
2 inflammatory response GO:0006954 9.5 CCR3 CXCR4 TNF
3 positive regulation of endothelial cell proliferation GO:0001938 9.37 CCR3 CXCL12
4 chemotaxis GO:0006935 9.33 CCR3 CXCL12 CXCR4
5 positive regulation of cell adhesion GO:0045785 9.26 CXCL12 TNF
6 response to virus GO:0009615 9.13 CXCL12 CXCR4 TNF
7 chemokine-mediated signaling pathway GO:0070098 8.8 CCR3 CXCL12 CXCR4

Molecular functions related to Aids Dementia Complex according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine receptor activity GO:0004950 8.96 CCR3 CXCR4
2 C-C chemokine binding GO:0019957 8.62 CCR3 CXCR4

Sources for Aids Dementia Complex

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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