MCID: ADS004
MIFTS: 33

Aids Dementia Complex malady

Rare diseases, Mental diseases categories

Summaries for Aids Dementia Complex

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MalaCards based summary: Aids Dementia Complex, also known as aids related cognitive impairment, is related to dementia and hiv-1. An important gene associated with Aids Dementia Complex is ITIH4 (inter-alpha-trypsin inhibitor heavy chain family, member 4). The compounds dizocilpine and memantine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and t cells, and related mouse phenotypes are liver/biliary system and cellular.

Aliases & Classifications for Aids Dementia Complex

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Sources:
41NIH Rare Diseases, 43Novoseek, 60UMLS
See all sources

Aids Dementia Complex, Aliases & Descriptions:

Name: Aids Dementia Complex 41 43 60
Aids Related Cognitive Impairment 41
 
Adc 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Mental diseases


Related Diseases for Aids Dementia Complex

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Graphical network of the top 20 diseases related to Aids Dementia Complex:



Diseases related to aids dementia complex

Symptoms for Aids Dementia Complex

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Drugs & Therapeutics for Aids Dementia Complex

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Drug clinical trials:

Search ClinicalTrials for Aids Dementia Complex

Search NIH Clinical Center for Aids Dementia Complex

Genetic Tests for Aids Dementia Complex

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Anatomical Context for Aids Dementia Complex

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MalaCards organs/tissues related to Aids Dementia Complex:

31
Brain, Testes, T cells, Cortex

Animal Models for Aids Dementia Complex or affiliated genes

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MGI Mouse Phenotypes related to Aids Dementia Complex:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.7PLAUR, ITIH4, B2M
2MP:00053847.9PLAUR, ITIH4, CCR3, B2M

Publications for Aids Dementia Complex

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Articles related to Aids Dementia Complex:

(show top 50)    (show all 184)
idTitleAuthorsYear
1
Memantine for AIDS dementia complex: open-label report of ACTG 301. (20400412)
2010
2
Validity of the CogState brief battery: relationship to standardized tests and sensitivity to cognitive impairment in mild traumatic brain injury, schizophrenia, and AIDS dementia complex. (19395350)
2009
3
High level HIV-1 DNA concentrations in brain tissues differentiate patients with post-HAART AIDS dementia complex or cardiovascular disease from those with AIDS. (19641870)
2009
4
Communication impairment in the AIDS dementia complex (ADC): a case report. (18242630)
2008
5
Prevalence of AIDS dementia complex: results from a statewide population-based registry of Alzheimer's disease and related disorders. (19058735)
2008
6
AIDS dementia complex in China. (17070055)
2007
7
Cerebrospinal fluid markers in central nervous system HIV infection and AIDS dementia complex. (18808988)
2007
8
AIDS dementia complex and Hashimoto encephalopathy in a senescent woman. (18033678)
2007
9
AIDS dementia complex. (16909695)
2006
10
Inflammation and neuroaxonal injury in multiple sclerosis and AIDS dementia complex: implications for neuroprotective treatment. (16138246)
2005
11
The AIDS dementia complex: clinical and basic neuroscience with implications for novel molecular therapies. (16260383)
2005
12
Involvement of quinolinic acid in AIDS dementia complex. (15639803)
2005
13
A multi-center 1H MRS study of the AIDS dementia complex: validation and preliminary analysis. (12766890)
2003
14
Elevated levels of soluble Fas and Fas ligand in cerebrospinal fluid of patients with AIDS dementia complex. (11240032)
2001
15
Human Herpesvirus 8 and Protection from AIDS Dementia Complex. (11867000)
2000
16
AIDS dementia complex. (10517932)
1999
17
Anomalies in Nef expression within the central nervous system of HIV-1 positive individuals/AIDS patients with or without AIDS dementia complex. (9639072)
1998
18
Pathogenic mechanisms of neuronal damage in the AIDS dementia complex. (9231153)
1997
19
The neuropathogenesis of the AIDS dementia complex. (9451964)
1997
20
The relationship between AIDS dementia complex and the presence of macrophage tropic and non-syncytium inducing isolates of human immunodeficiency virus type 1 in the cerebrospinal fluid. (8799207)
1996
21
The cellular basis of central nervous system HIV-1 infection and the AIDS dementia complex: introduction. (16873153)
1996
22
Genetic and biological analysis of variants derived from the cerebrospinal fluid of HIV type 1 subtype B- and D- infected patients with and without AIDS dementia complex. (8947301)
1996
23
Epidemiology of AIDS dementia complex in Europe. AIDS in Europe Study Group. (8528731)
1996
24
Transgenic models in the study of AIDS dementia complex. (8608719)
1996
25
Cellular basis of HIV infection of the CNS and the AIDS dementia complex: oligodendrocyte. (16873159)
1996
26
AIDS dementia complex: incidence, clinical profile and impact of zidovudine treatment*. (21284769)
1996
27
Astrocytes and the AIDS dementia complex. (16873158)
1996
28
Review of antiretroviral therapy in the prevention of HIV-related AIDS dementia complex (ADC). (7614899)
1995
29
Trypsin inhibition: a potential cause of cobalamin deficiency common to the pathogenesis of Alzheimer-type dementia and AIDS dementia complex? (8531843)
1995
30
More acquired immunodeficiency syndrome (AIDS) dementia complex in Japan? (8563090)
1995
31
Management of AIDS dementia complex and HIV-1 infection of the nervous system. (8819589)
1995
32
The role of the consultation-liaison nurse. Caring for patients with AIDS dementia complex. (8667308)
1995
33
Neuropsychological characterization of the AIDS dementia complex and rationalization of a test battery. (8018042)
1994
34
Cerebrospinal fluid HIV-1 p24 antigen and culture: sensitivity and specificity for AIDS-dementia complex. (8021661)
1994
35
SPECT imaging of the brain: comparison of findings in patients with chronic fatigue syndrome, AIDS dementia complex, and major unipolar depression. (8141022)
1994
36
Zidovudine treatment of the AIDS dementia complex: results of a placebo-controlled trial. AIDS Clinical Trials Group. (8489204)
1993
37
Cerebrospinal fluid beta 2-microglobulin in patients with AIDS dementia complex: an expanded series including response to zidovudine treatment. (1616651)
1992
38
Cerebrospinal fluid myelin basic protein in AIDS dementia complex: relationship to disease progression and zidovudine treatment. (1281644)
1992
39
Proton MR spectroscopy of the brain in AIDS dementia complex. (1629410)
1992
40
Single photon emission computed tomography with 99mTc-HMPAO in HIV-1 infection: a help in early diagnosis of AIDS dementia complex. (1927637)
1991
41
Detection of cerebrospinal fluid antibodies against myelin basic protein in patients with AIDS dementia complex. (1720316)
1991
42
Early HIV-1 infection and the AIDS dementia complex. (2300258)
1990
43
AIDS dementia complex: brain high-energy phosphate metabolite deficits. (2367655)
1990
44
The significant other's role in improving quality of life in persons with AIDS dementia complex. (2527929)
1989
45
Declining incidence of AIDS dementia complex after introduction of zidovudine treatment. (2510843)
1989
46
Tumor necrosis factor alpha (TNF alpha) and neurological diseases. Failure in detecting TNF alpha in the cerebrospinal fluid from patients with multiple sclerosis, AIDS dementia complex, and brain tumours. (2723041)
1989
47
AIDS-dementia-complex: pathology, pathogenesis and future directions. (2670816)
1989
48
Neuropsychiatric aspects of AIDS dementia complex: a report on a clinical series. (3200506)
1988
49
The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex. (3277272)
1988
50
HIV antigen in the brains of patients with the AIDS dementia complex. (3296948)
1987

Variations for Aids Dementia Complex

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Expression for genes affiliated with Aids Dementia Complex

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Search GEO for disease gene expression data for Aids Dementia Complex.

Pathways for genes affiliated with Aids Dementia Complex

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Compounds for genes affiliated with Aids Dementia Complex

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Compounds related to Aids Dementia Complex according to GeneCards Suite gene sharing:

(show top 50)    (show all 59)
idCompoundScoreTop Affiliating Genes
1dizocilpine439.8ITIH4, TAT
2memantine43 28 49 1212.8ITIH4, TAT
32,5-oligoadenylate439.7TAT, B2M
4ccl343 2810.7TAT, CCR3
5corticosterone43 59 2411.6TAT, ITIH4
6asparagine439.6TAT, ITIH4
7urea43 24 1211.6ITIH4, B2M
8nifedipine43 28 49 1212.6ITIH4, B2M
9glycolipid439.5PLAUR, ITIH4
10amiloride43 28 1211.5PLAUR, ITIH4
11lead439.5B2M, TAT
12aprotinin43 1210.5ITIH4, PLAUR
13vincristine43 49 1211.5TAT, B2M
14neopterin439.4PLAUR, B2M
15uric acid43 2410.4B2M, PLAUR
16suramin43 28 1211.4PLAUR, ITIH4
17cocaine43 1210.4ITIH4, TAT
18inositol439.4TAT, ITIH4
19opiate439.3TAT, ITIH4, CCR3
20chloroquine43 2 49 28 1213.3B2M, ITIH4, TAT
21zidovudine43 49 1211.3TAT, ITIH4, B2M
22vitamin-e439.3TAT, ITIH4, B2M
23morphine43 49 28 1212.3TAT, ITIH4, CCR3
24rantes439.3TAT, ITIH4, CCR3
25cyclosporin a43 28 5911.3TAT, ITIH4, B2M
26lactate439.2B2M, ITIH4, TAT
27aspartate439.2TAT, ITIH4, B2M
28adenylate439.2CCR3, ITIH4, TAT
29biotin43 24 1211.1PLAUR, ITIH4, B2M
30paraffin439.1PLAUR, ITIH4, B2M
31pge2439.1PLAUR, ITIH4, B2M
32thymidine43 2410.0PLAUR, CCR3, B2M
33iron43 249.9B2M, PLAUR, TAT
34arginine438.8ITIH4, PLAUR, TAT
35dexamethasone43 49 28 1211.8TAT, PLAUR, CCR3
36vegf438.8TAT, PLAUR, B2M
37indomethacin43 28 59 1211.5B2M, ITIH4, PLAUR, TAT
38actinomycin d438.5CCR3, ITIH4, PLAUR, TAT
39glutamine438.5B2M, ITIH4, PLAUR, TAT
40heparin43 28 24 1211.5CCR3, ITIH4, PLAUR, TAT
41cycloheximide438.5B2M, ITIH4, PLAUR, TAT
42butyrate438.4TAT, PLAUR, CCR3, B2M
43serine438.4TAT, PLAUR, ITIH4, B2M
44genistein43 28 59 2 24 1213.4TAT, PLAUR, CCR3, B2M
45oxygen43 249.4TAT, PLAUR, CCR3
46tyrosine438.4CCR3, ITIH4, PLAUR, TAT
47retinoic acid43 249.4TAT, PLAUR, CCR3, B2M
48estrogen438.2TAT, PLAUR, B2M
49alanine438.0TAT, PLAUR, ITIH4, CCR3, B2M
50cysteine438.0B2M, CCR3, ITIH4, PLAUR, TAT

GO Terms for genes affiliated with Aids Dementia Complex

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Cellular components related to Aids Dementia Complex according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endoplasmic reticulum lumenGO:00057889.1PLAUR, B2M

Biological processes related to Aids Dementia Complex according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chemotaxisGO:00069359.1PLAUR, CCR3

Products for genes affiliated with Aids Dementia Complex

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  • Antibodies
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  • Kits and Assays

Sources for Aids Dementia Complex

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet