MCID: ANH001
MIFTS: 29

Ainhum malady

Skin diseases category

Summaries for Ainhum

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8Disease Ontology, 63Wikipedia, 46OMIM, 32MalaCards
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Disease Ontology:8 A connective tissue disease that results in increasing fibrous constriction and ultimately in spontaneous amputation of the toes and especially the little toes. a painful constriction of the base of the fifth toe frequently followed by bilateral spontaneous amputation (autoamputation) a few years later.

MalaCards: Ainhum, also known as spontaneous dactylolysis, is related to x-linked ichthyosis and syringomyelia. An important gene associated with Ainhum is LOR (loricrin). Affiliated tissues include skin.

Wikipedia:63 Ainhum (from Portuguese, pronounced īn-yoom´, i´num or ān´hum; also known as banko-kerende and... more...

Description from OMIM:46 103400

Aliases & Classifications for Ainhum

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8Disease Ontology, 42NIH Rare Diseases, 60UMLS, 56SNOMED-CT, 39NCIt, 46OMIM, 27ICD9CM, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


Aliases & Descriptions:

ainhum 8 42 60
spontaneous dactylolysis 42
dactylolysis spontanea 8


External Ids:

Disease Ontology8 DOID:11329
NCIt39 C84544
OMIM46 103400
SNOMED-CT56 51404004, 38528001
ICD9CM27 136.0
MeSH34 D000387
ICD1025 L94.6

Related Diseases for Ainhum

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Ainhum:



Diseases related to ainhum

Clinical Features for Ainhum

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46OMIM
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Clinical features from OMIM:

103400

Drugs & Therapeutics for Ainhum

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Ainhum

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Anatomical Context for Ainhum

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Sources:
32MalaCards
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MalaCards organs/tissues related to Ainhum:

32
Skin

Animal Models for Ainhum or affiliated genes

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Publications for Ainhum

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50PubMed
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Articles related to Ainhum:

(show top 50)    (show all 99)
idTitleAuthorsYear
1
Ainhum (dactylolysis spontanea): a case with hands and feet involvement. (23872549)
2013
2
Vohwinkel syndrome: treatment of pseudo-ainhum. (20465619)
2010
3
Clouston syndrome associated with severe congenital pseudo-ainhum. (17542906)
2007
4
Undiagnosed purpura: a case of autoerythrocyte sensitization syndrome associated with dermatitis artefacta and pseudo-ainhum. (17050937)
2006
5
Dactylolysis spontanea or ainhum involving the big toe. (16331779)
2005
6
Surgical correction of pseudo-ainhum in Vohwinkel syndrome. (7561409)
1995
7
Case report: ainhum (spontaneous dactylolysis) in a 65-year-old American black man. (1539609)
1992
8
The surgical pathology of ainhum (dactylolysis spontanea). (2423578)
1986
9
Ainhum (dactylolysis spontanea). Report of a bilateral case and literature review. (3806378)
1986
10
Ainhum--a case report. (4078367)
1985
11
Pseudo-ainhum, angiodysplasia and focal acral hyperkeratosis. (4093943)
1985
12
Ainhum (dactylosis spontanea): a literature review and case report. (7264168)
1981
13
Ainhum, trichosporiosis and Z-plasty. (7195834)
1981
14
Ainhum; dactylolysis spontanea. (6949057)
1981
15
Ainhum and angiodysplasia. (6115161)
1981
16
Ainhum: treatment with intralesional steroids. (1279067)
1976
17
Letter: Ainhum. (51987)
1975
18
Ainhum (dactylolysis spontanea): report of a case. (1056506)
1975
19
An investigation into the prevalence and geographical distribution of Ainhum in the Tsolo district of the Transkei. (4432202)
1974
20
Dactylolysis spontanea (ainhum). (5528014)
1970
21
Polydactyly with ainhum in all the extra digits, hyperkeratosis palmaris et plantaris, and idiopathic eosinophilia. A new association. (5764299)
1969
22
Ainhum (dactylolysis spontanea). (5241101)
1968
23
Clinico-etiologic features of ainhum. (5727816)
1968
24
Ainhum in a female child involving a great toe. (6030802)
1967
25
Ainhum with keratoderma palmaris et plantaris with keratosis pilaris in an Indian female. (5954187)
1966
26
AINHUM: AN ACCOUNT OF FIFTY-FOUR PATIENTS WITH SPECIAL REFERENCE TO ETIOLOGY AND TREATMENT. (14296245)
1965
27
TRUE AINHUM: ITS DISTINCTIVE AND DIFFERENTIATING FEATURES. (14296246)
1965
28
Ainhum. Report of an atypical case. (14040961)
1963
29
AINHUM AND PSEUDOAINHUM. REPORT OF THREE CASES. (14042848)
1963
30
Ainhum. (13766019)
1961
31
Ainhum. (13706613)
1961
32
Bilateral ainhum treated by multiple Z-plasties. (13657730)
1959
33
Ainhum of the fingers: a case from Sierra Leone. (13625376)
1958
34
Ainhum: a case report. (13538861)
1958
35
A plethysmographic study of the toe of a patient with ainhum. (13434515)
1957
36
Ainhum. (13274672)
1956
37
Ainhum. (13377158)
1956
38
Report of two additional cases and an analysis of the pathogenesis of ainhum on the Isthmus of Panama. (15443045)
1950
39
Ainhum; report of a case with bilateral involvement. (14776842)
1950
40
Ainhum or dactylolysis spontanea; report of a case. (18903108)
1948
41
Constriction of the finger simulating ainhum; report of a congenital case. (18886283)
1948
42
Ainhum; report of a case in which the patient was a white woman with diabetes mellitus. (20288664)
1947
43
Ainhum. (20995060)
1946
44
Ainhum. (21000223)
1946
45
Pityriasis Rubra Pilaris with Ainhum and Syringomyelia. (19993248)
1946
46
Ainhum. (21001310)
1946
47
Pityriasis rubra pilaris with ainhum and syringomyelia. (21024123)
1946
48
Ainhum; a clinical summary of forty-five cases on the Isthmus of Panama. (21020357)
1945-1946
49
Ainhum (Dactylolysis Spontanea): Report of Two Cases from Illinois. (17858690)
1945
50
Ainhum or "Ring-Toe". (20891321)
1913

Genetic Variations for Ainhum

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Expression for genes affiliated with Ainhum

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ainhum

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Pathways for genes affiliated with Ainhum

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Compounds for genes affiliated with Ainhum

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GO Terms for genes affiliated with Ainhum

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Products for genes affiliated with Ainhum

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  • Antibodies
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Sources for Ainhum

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet