MCID: ANH001
MIFTS: 27

Ainhum malady

Skin category

Summaries for Ainhum

Sources:
8Disease Ontology, 64Wikipedia, 47OMIM, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Disease Ontology:8 A connective tissue disease that results in increasing fibrous constriction and ultimately in spontaneous amputation of the toes and especially the little toes. a painful constriction of the base of the fifth toe frequently followed by bilateral spontaneous amputation (autoamputation) a few years later.

MalaCards: Ainhum, also known as spontaneous dactylolysis, is related to vohwinkel syndrome and x-linked ichthyosis. An important gene associated with Ainhum is LOR (loricrin).

Wikipedia:64 Ainhum (from Portuguese, pronounced īn-yoom´, i´num or ān´hum) (also known as Banko-kerende and... more...

Description from OMIM:47 103400

Aliases & Classifications for Ainhum

Sources:
8Disease Ontology, 43NIH Rare Diseases, 61UMLS, 57SNOMED-CT, 40NCIt, 47OMIM, 27ICD9CM, 35MeSH, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin


Aliases & Descriptions:

ainhum 8 43 61
spontaneous dactylolysis 43
dactylolysis spontanea 8


External Ids:

Disease Ontology8 DOID:11329
NCIt40 C84544
OMIM47 103400
SNOMED-CT57 51404004, 38528001
ICD9CM27 136.0
MeSH35 D000387
ICD1025 L94.6

Related Diseases for Ainhum

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Ainhum via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 118)
idRelated DiseaseScoreTop Affiliating Genes
1vohwinkel syndrome10.1
2x-linked ichthyosis10.0
3syringomyelia10.0
4pityriasis rubra pilaris10.0
5angiodysplasia10.0
6systemic scleroderma10.0
7erythrokeratodermia variabilis et progressiva10.0
8keratoderma10.0
9ifap syndrome with or without bresheck syndrome10.0
10clouston syndrome9.8
11leopard syndrome9.8
12sjogren-larsson syndrome9.8
13fucosidosis9.8
14rothmund-thomson syndrome9.8
15bart-pumphrey syndrome9.8
16epidermolytic hyperkeratosis9.8
17acanthosis nigricans9.8
18cutaneous lupus erythematosus9.8
19epidermolysis bullosa simplex9.8
20mongolian spot9.8
21papillon-lefevre disease9.8
22monilethrix9.8
23hailey-hailey disease9.8
24costello syndrome9.8
25werner syndrome9.8
26polydactyly9.8
27reactive arthritis9.8
28lipoid proteinosis9.8
29fabry disease9.8
30wolman disease9.8
31tyrosinemia type ii9.8
32n syndrome9.8
33bloch-sulzberger syndrome9.8
34alopecia9.8
35cardiofaciocutaneous syndrome9.8
36oculocutaneous albinism type 19.8
37ichthyosis, acquired9.8
38acrokeratoelastoidosis of costa9.8
39acute febrile neutrophilic dermatosis9.8
40kanzaki disease9.8
41schindler disease, type 19.8
42ameloonychohypohidrotic syndrome9.8
43kindler syndrome9.8
44craniosynostosis, anal anomalies, and porokeratosis9.8
45sialidosis type i9.8
46ramon syndrome9.8
47children's interstitial lung disease9.8
48zunich neuroectodermal syndrome9.8
49zlotogora syndrome9.8
50cobb syndrome9.8

Graphical network of the top 20 diseases related to Ainhum:



Diseases related to ainhum

Clinical Features for Ainhum

Sources:
47OMIM
See all sources

Clinical features from OMIM:

103400

Drugs & Therapeutics for Ainhum

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Ainhum

Drug clinical trials:

Search ClinicalTrials for Ainhum

Search NIH Clinical Center for Ainhum

Search CenterWatch for Ainhum

Genetic Tests for Ainhum

Anatomical Context for Ainhum

Animal Models for Ainhum or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Ainhum

Sources:
51PubMed
See all sources

Articles related to Ainhum:

(show top 50)    (show all 99)
idTitleAuthorsYear
1
Ainhum (dactylolysis spontanea): a case with hands and feet involvement. (23872549)
2013
2
Penile pseudo-ainhum associated with lichen sclerosus et atrophicus. (24195101)
2013
3
Vohwinkel syndrome: treatment of pseudo-ainhum. (20465619)
2010
4
Clouston syndrome associated with severe congenital pseudo-ainhum. (17542906)
2007
5
An unusual cause of ulceration: ainhum (dactylolysis spontanea). (17924881)
2007
6
Undiagnosed purpura: a case of autoerythrocyte sensitization syndrome associated with dermatitis artefacta and pseudo-ainhum. (17050937)
2006
7
A rare association of epidermal nevus syndrome and ainhum-like digital constrictions. (12220284)
2002
8
Images and diagnoses. Ainhum. (10786458)
2000
9
Pseudo-ainhum in discoid lupus erythematosus. (9609990)
1998
10
Case report: ainhum (spontaneous dactylolysis) in a 65-year-old American black man. (1539609)
1992
11
Ainhum in a 12-year-old girl. (3780683)
1986
12
Ainhum (dactylolysis spontanea). Report of a bilateral case and literature review. (3806378)
1986
13
Ainhum--a case report. (4078367)
1985
14
Ainhum. (6852001)
1983
15
Ainhum (dactylosis spontanea): a literature review and case report. (7264168)
1981
16
Ainhum, trichosporiosis and Z-plasty. (7195834)
1981
17
Ainhum: treatment with intralesional steroids. (1279067)
1976
18
Letter: Ainhum. (51987)
1975
19
Editorial: Ainhum. (49609)
1975
20
Letter: Ainhum. (50529)
1975
21
Ainhum (dactylolysis spontanea): report of a case. (1056506)
1975
22
An investigation into the prevalence and geographical distribution of Ainhum in the Tsolo district of the Transkei. (4432202)
1974
23
Ainhum (dactylolysis spontanea): a review of the literature and a report of two cases. (4927166)
1971
24
Clinico-etiologic features of ainhum. (5727816)
1968
25
Hereditary keratodermia and ainhum. (6064941)
1967
26
Ainhum. A rare disease. (6039756)
1967
27
A case of congenital pseudo ainhum. (5882081)
1965
28
AINHUM: AN ACCOUNT OF FIFTY-FOUR PATIENTS WITH SPECIAL REFERENCE TO ETIOLOGY AND TREATMENT. (14296245)
1965
29
AINHUM (DACTYLOLYSIS SPONTANEA). (14342009)
1965
30
Ainhum. Report of an atypical case. (14040961)
1963
31
Ainhum. A clinical and etiological study of 83 cases. (13873764)
1961
32
Ainhum. (13706613)
1961
33
Bilateral ainhum treated by multiple Z-plasties. (13657730)
1959
34
Ainhum: a case report. (13538861)
1958
35
A plethysmographic study of the toe of a patient with ainhum. (13434515)
1957
36
Ainhum. (13463040)
1957
37
Ainhum. (13274672)
1956
38
Ainhum. (13377158)
1956
39
Ainhum. (15412193)
1950
40
Report of two additional cases and an analysis of the pathogenesis of ainhum on the Isthmus of Panama. (15443045)
1950
41
Ainhum; report of a case with bilateral involvement. (14776842)
1950
42
Ainhum; report of a case in which the patient was a white woman with diabetes mellitus. (20288664)
1947
43
Ainhum. (20995060)
1946
44
Ainhum. (21000223)
1946
45
Ainhum. (21001310)
1946
46
Etiologic concepts and pathologic aspects of ainhum. (20993495)
1946
47
Pityriasis rubra pilaris with ainhum and syringomyelia. (21024123)
1946
48
Ainhum. (21012021)
1946
49
Ainhum; a clinical summary of forty-five cases on the Isthmus of Panama. (21020357)
1945-1946
50
Ainhum (Dactylolysis Spontanea): Report of Two Cases from Illinois. (17858690)
1945

Genetic Variations for Ainhum

Expression for genes affiliated with Ainhum

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Ainhum

Search GEO for disease gene expression data for Ainhum.

Pathways for genes affiliated with Ainhum

Compounds for genes affiliated with Ainhum

GO Terms for genes affiliated with Ainhum

Products for genes affiliated with Ainhum

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Ainhum

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet