MCID: ANH001
MIFTS: 29

Ainhum malady

Rare diseases, Skin diseases categories

Summaries for Ainhum

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9Disease Ontology, 44NIH Rare Diseases, 66Wikipedia, 48OMIM, 34MalaCards
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NIH Rare Diseases:44 Ainhum is the autoamputation of a finger or toe as a result of a fibrotic band that constricts the finger or toe until it falls off. ainhum most often affects the fifth toe on both feet. ainhum is believed to be triggered by some sort of trauma, but the exact reason why it happens is not well understood. the condition mainly affects people that live in tropical regions.  last updated: 5/8/2014

MalaCards: Ainhum, also known as spontaneous dactylolysis, is related to vohwinkel syndrome and syringomyelia. Affiliated tissues include skin.

Disease Ontology:9 A connective tissue disease that results in increasing fibrous constriction and ultimately in spontaneous amputation of the toes and especially the little toes. a painful constriction of the base of the fifth toe frequently followed by bilateral spontaneous amputation (autoamputation) a few years later.

Wikipedia:66 Ainhum (from Portuguese, pronounced ?n-yoom more...

Description from OMIM:48 103400

Aliases & Classifications for Ainhum

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9Disease Ontology, 44NIH Rare Diseases, 63UMLS, 48OMIM, 36MeSH, 28ICD9CM, 41NCIt, 59SNOMED-CT, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Skin diseases


Aliases & Descriptions:

ainhum 9 44 63
spontaneous dactylolysis 44
dactylolysis spontanea 9


External Ids:

Disease Ontology9 DOID:11329
OMIM48 103400
MeSH36 D000387
SNOMED-CT59 38528001, 51404004
ICD9CM28 136.0
NCIt41 C84544
ICD1026 L94.6

Related Diseases for Ainhum

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18GeneCards, 19GeneDecks
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Diseases related to Ainhum via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 123)
idRelated DiseaseScoreTop Affiliating Genes
1vohwinkel syndrome10.1
2syringomyelia10.0
3x-linked ichthyosis10.0
4pityriasis rubra pilaris10.0
5angiodysplasia10.0
6systemic scleroderma10.0
7erythrokeratodermia variabilis et progressiva10.0
8keratoderma10.0
9ifap syndrome with or without bresheck syndrome10.0
10rothmund-thomson syndrome9.9
11polydactyly9.9
12reactive arthritis9.9
13epidermolytic hyperkeratosis9.9
14acanthosis nigricans9.9
15cutaneous lupus erythematosus9.9
16epidermolysis bullosa simplex9.9
17mongolian spot9.9
18papillon-lefevre disease9.9
19monilethrix9.9
20hailey-hailey disease9.9
21costello syndrome9.9
22werner syndrome9.9
23bart-pumphrey syndrome9.9
24lipoid proteinosis9.9
25fabry disease9.9
26wolman disease9.9
27bloch-sulzberger syndrome9.9
28tyrosinemia type ii9.9
29leopard syndrome9.9
30clouston syndrome9.9
31sjogren-larsson syndrome9.9
32fucosidosis9.9
33alopecia9.9
34dermatitis9.9
35diabetes mellitus9.9
36eosinophilia9.9
37keratosis9.9
38lupus erythematosus9.9
39purpura9.9
40cardiofaciocutaneous syndrome9.9
41oculocutaneous albinism type 19.9
42acrokeratoelastoidosis of costa9.9
43acute febrile neutrophilic dermatosis9.9
44ameloonychohypohidrotic syndrome9.9
45arthrogryposis and ectodermal dysplasia9.9
46children's interstitial lung disease9.9
47cobb syndrome9.9
48craniosynostosis, anal anomalies, and porokeratosis9.9
49degos 'en cocarde' erythrokeratoderma9.9
50dermatoleukodystrophy9.9

Graphical network of the top 20 diseases related to Ainhum:



Diseases related to ainhum

Symptoms for Ainhum

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48OMIM
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Clinical features from OMIM:

103400

Drugs & Therapeutics for Ainhum

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Genetic Tests for Ainhum

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Anatomical Context for Ainhum

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34MalaCards
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MalaCards organs/tissues related to Ainhum:

34
Skin

Animal Models for Ainhum or affiliated genes

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Publications for Ainhum

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53PubMed
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Articles related to Ainhum:

(show top 50)    (show all 99)
idTitleAuthorsYear
1
Ainhum (dactylolysis spontanea): a case with hands and feet involvement. (23872549)
2013
2
Penile pseudo-ainhum associated with lichen sclerosus et atrophicus. (24195101)
2013
3
Palmoplantar keratoderma, pseudo-ainhum, and universal atrichia: A new patient and review of the palmoplantar keratoderma-congenital alopecia syndrome. (20635335)
2010
4
Destructive deformation of the digits with auto-amputation: a review of pseudo-ainhum. (17567298)
2007
5
Clouston syndrome associated with severe congenital pseudo-ainhum. (17542906)
2007
6
Dactylolysis spontanea or ainhum involving the big toe. (16331779)
2005
7
Ainhum (dactylolysis spontanea): a radiological survey of 6000 patients. (12500788)
2002
8
Pseudo-ainhum in discoid lupus erythematosus. (9609990)
1998
9
Ainhum in supernumery fingers. (20953032)
1995
10
Case report: ainhum (spontaneous dactylolysis) in a 65-year-old American black man. (1539609)
1992
11
Ainhum. (2559515)
1989
12
The surgical pathology of ainhum (dactylolysis spontanea). (2423578)
1986
13
Ainhum in a 12-year-old girl. (3780683)
1986
14
Ainhum (dactylolysis spontanea). Report of a bilateral case and literature review. (3806378)
1986
15
Ainhum--a case report. (4078367)
1985
16
Ainhum (dactylosis spontanea): a literature review and case report. (7264168)
1981
17
Ainhum, trichosporiosis and Z-plasty. (7195834)
1981
18
Ainhum. (7418704)
1980
19
Ainhum. (1279064)
1976
20
Ainhum: treatment with intralesional steroids. (1279067)
1976
21
Letter: Ainhum. (51987)
1975
22
Letter: Ainhum. (49726)
1975
23
Ainhum (dactylolysis spontanea): a review of the literature and a report of two cases. (4927166)
1971
24
Ainhum (dactylolysis spontanea). (5241101)
1968
25
Hereditary keratodermia and ainhum. (6064941)
1967
26
The clinico-roentgenologic features of ainhum. (6028958)
1967
27
Ainhum with keratoderma palmaris et plantaris with keratosis pilaris in an Indian female. (5954187)
1966
28
A case of congenital pseudo ainhum. (5882081)
1965
29
AINHUM: AN ACCOUNT OF FIFTY-FOUR PATIENTS WITH SPECIAL REFERENCE TO ETIOLOGY AND TREATMENT. (14296245)
1965
30
AINHUM (DACTYLOLYSIS SPONTANEA). (14342009)
1965
31
Ainhum. Report of an atypical case. (14040961)
1963
32
Dactylolysis spontanea (ainhum). Report of a case treated by the surgical procedure known as Z-plasty. (14012203)
1963
33
AINHUM AND PSEUDOAINHUM. REPORT OF THREE CASES. (14042848)
1963
34
Ainhum. A clinical and etiological study of 83 cases. (13873764)
1961
35
Ainhum. (13766019)
1961
36
Ainhum-dactylolysis spontanea-a case report. (13751291)
1960
37
A plethysmographic study of the toe of a patient with ainhum. (13434515)
1957
38
Ainhum. (15412193)
1950
39
Ainhum (dactylolysis spontanea); a review of 10 cases. (15433202)
1950
40
Ainhum or dactylolysis spontanea; report of a case. (18903108)
1948
41
Constriction of the finger simulating ainhum; report of a congenital case. (18886283)
1948
42
Ainhum; report of a case in which the patient was a white woman with diabetes mellitus. (20288664)
1947
43
Ainhum. (20995060)
1946
44
Ainhum. (20289413)
1946
45
Ainhum. (21000223)
1946
46
Pityriasis Rubra Pilaris with Ainhum and Syringomyelia. (19993248)
1946
47
Ainhum. (21001310)
1946
48
Ainhum; report of a case. (20994158)
1946
49
AINHUM. (17865998)
1928
50
Ainhum or "Ring-Toe". (20891321)
1913

Variations for Ainhum

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Expression for genes affiliated with Ainhum

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Pathways for genes affiliated with Ainhum

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Compounds for genes affiliated with Ainhum

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GO Terms for genes affiliated with Ainhum

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Products for genes affiliated with Ainhum

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Sources for Ainhum

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet