MCID: ANH001
MIFTS: 26

Ainhum malady

Rare diseases, Skin diseases categories

Aliases & Classifications for Ainhum

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Ainhum, Aliases & Descriptions:

Name: Ainhum 9 41 60
Spontaneous Dactylolysis 41
 
Dactylolysis Spontanea 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Skin diseases


External Ids:

Disease Ontology9 DOID:11329
MeSH33 D000387
ICD9CM27 136.0
SNOMED-CT55 38528001, 51404004
NCIt38 C84544
ICD1025 L94.6

Summaries for Ainhum

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NIH Rare Diseases:41 Ainhum is the autoamputation of a finger or toe as a result of a fibrotic band that constricts the finger or toe until it falls off. ainhum most often affects the fifth toe on both feet. ainhum is believed to be triggered by some sort of trauma, but the exact reason why it happens is not well understood. the condition mainly affects people that live in tropical regions.  last updated: 5/8/2014

MalaCards based summary: Ainhum, also known as spontaneous dactylolysis, is related to vohwinkel syndrome and pityriasis rubra pilaris, and has symptoms including autosomal dominant inheritanceand amniotic constriction ring. Affiliated tissues include skin.

Disease Ontology:9 A connective tissue disease that results in increasing fibrous constriction and ultimately in spontaneous amputation of the toes and especially the little toes. a painful constriction of the base of the fifth toe frequently followed by bilateral spontaneous amputation (autoamputation) a few years later.

Wikipedia:63 Ainhum (from Portuguese, pronounced ?n-yoom more...

Related Diseases for Ainhum

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Diseases related to Ainhum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 111)
idRelated DiseaseScoreTop Affiliating Genes
1vohwinkel syndrome10.1
2pityriasis rubra pilaris10.0
3syringomyelia10.0
4angiodysplasia10.0
5keratoderma10.0
6erythrokeratodermia variabilis et progressiva9.9
7fucosidosis9.9
8restrictive dermopathy, lethal9.9
9aphakia, congenital primary9.9
10muir-torre syndrome9.9
11ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive9.9
12keratolytic winter erythema9.9
13werner syndrome9.9
14epidermolysis bullosa simplex, ogna type9.9
15costello syndrome9.9
16albinism, oculocutaneous, type ia9.9
17papillon-lefevre syndrome9.9
18ehlers-danlos syndrome, type viii9.9
19epidermolytic hyperkeratosis9.9
20epidermolysis bullosa simplex, dowling-meara type9.9
21monilethrix9.9
22keratoderma, palmoplantar, with deafness9.9
23tyrosinemia, type ii9.9
24sjogren-larsson syndrome9.9
25prolidase deficiency9.9
26kindler syndrome9.9
27schindler disease, type i9.9
28kanzaki disease9.9
29ichthyosis, x-linked9.9
30keratosis follicularis spinulosa decalvans, x-linked9.9
31fabry disease9.9
32cardiofaciocutaneous syndrome9.9
33urbach-wiethe disease9.9
34ichthyosis, autosomal recessive 4b9.9
35epidermolysis bullosa, pretibial9.9
36hailey-hailey disease9.9
37sialidosis, type i9.9
38meleda disease9.9
39wolman disease9.9
40ichthyosis histrix, curth-macklin type9.9
41epidermolysis bullosa simplex, koebner type9.9
42darier disease9.9
43proteus syndrome, somatic9.9
44olmsted syndrome9.9
45chime syndrome9.9
46incontinentia pigmenti, type ii9.9
47child syndrome9.9
48alopecia9.9
49systemic scleroderma9.9
50congenital ichthyosiform erythroderma9.9

Graphical network of the top 20 diseases related to Ainhum:



Diseases related to ainhum

Symptoms for Ainhum

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HPO human phenotypes related to Ainhum:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 amniotic constriction ring HP:0009775

Drugs & Therapeutics for Ainhum

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Drug clinical trials:

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Genetic Tests for Ainhum

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Anatomical Context for Ainhum

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MalaCards organs/tissues related to Ainhum:

31
Skin

Animal Models for Ainhum or affiliated genes

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Publications for Ainhum

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Articles related to Ainhum:

(show top 50)    (show all 101)
idTitleAuthorsYear
1
Familial ainhum: a case report of multiple toe involvement in a father and son, staging of ainhum with insight into different types of constricting bands. (25657437)
2015
2
Ainhum leading to fifth-digit amputation. (25440870)
2015
3
Reversal of pseudo-ainhum with acitretin in Camisa's syndrome. (25382531)
2014
4
Ainhum (dactylolysis spontanea): a case with hands and feet involvement. (23872549)
2013
5
Penile pseudo-ainhum associated with lichen sclerosus et atrophicus. (24195101)
2013
6
Palmoplantar keratoderma, pseudo-ainhum, and universal atrichia: A new patient and review of the palmoplantar keratoderma-congenital alopecia syndrome. (20635335)
2010
7
Destructive deformation of the digits with auto-amputation: a review of pseudo-ainhum. (17567298)
2007
8
Clouston syndrome associated with severe congenital pseudo-ainhum. (17542906)
2007
9
Dactylolysis spontanea or ainhum involving the big toe. (16331779)
2005
10
Ainhum (dactylolysis spontanea): a radiological survey of 6000 patients. (12500788)
2002
11
Pseudo-ainhum in discoid lupus erythematosus. (9609990)
1998
12
Ainhum in supernumery fingers. (20953032)
1995
13
Case report: ainhum (spontaneous dactylolysis) in a 65-year-old American black man. (1539609)
1992
14
Ainhum. (2559515)
1989
15
The surgical pathology of ainhum (dactylolysis spontanea). (2423578)
1986
16
Ainhum in a 12-year-old girl. (3780683)
1986
17
Ainhum (dactylolysis spontanea). Report of a bilateral case and literature review. (3806378)
1986
18
Ainhum--a case report. (4078367)
1985
19
Ainhum (dactylosis spontanea): a literature review and case report. (7264168)
1981
20
Ainhum, trichosporiosis and Z-plasty. (7195834)
1981
21
Ainhum. (7418704)
1980
22
Ainhum. (1279064)
1976
23
Ainhum: treatment with intralesional steroids. (1279067)
1976
24
Letter: Ainhum. (51987)
1975
25
Letter: Ainhum. (49726)
1975
26
Ainhum (dactylolysis spontanea): a review of the literature and a report of two cases. (4927166)
1971
27
Ainhum (dactylolysis spontanea). (5241101)
1968
28
Hereditary keratodermia and ainhum. (6064941)
1967
29
The clinico-roentgenologic features of ainhum. (6028958)
1967
30
Ainhum with keratoderma palmaris et plantaris with keratosis pilaris in an Indian female. (5954187)
1966
31
A case of congenital pseudo ainhum. (5882081)
1965
32
AINHUM: AN ACCOUNT OF FIFTY-FOUR PATIENTS WITH SPECIAL REFERENCE TO ETIOLOGY AND TREATMENT. (14296245)
1965
33
AINHUM (DACTYLOLYSIS SPONTANEA). (14342009)
1965
34
Ainhum. Report of an atypical case. (14040961)
1963
35
Dactylolysis spontanea (ainhum). Report of a case treated by the surgical procedure known as Z-plasty. (14012203)
1963
36
Ainhum. A clinical and etiological study of 83 cases. (13873764)
1961
37
Ainhum-dactylolysis spontanea-a case report. (13751291)
1960
38
A plethysmographic study of the toe of a patient with ainhum. (13434515)
1957
39
Ainhum. (15412193)
1950
40
Ainhum (dactylolysis spontanea); a review of 10 cases. (15433202)
1950
41
Ainhum or dactylolysis spontanea; report of a case. (18903108)
1948
42
Constriction of the finger simulating ainhum; report of a congenital case. (18886283)
1948
43
Ainhum; report of a case in which the patient was a white woman with diabetes mellitus. (20288664)
1947
44
Ainhum. (20995060)
1946
45
Ainhum. (20289413)
1946
46
Ainhum. (21000223)
1946
47
Pityriasis Rubra Pilaris with Ainhum and Syringomyelia. (19993248)
1946
48
Ainhum. (21001310)
1946
49
Ainhum; report of a case. (20994158)
1946
50
Ainhum or "Ring-Toe". (20891321)
1913

Variations for Ainhum

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Expression for genes affiliated with Ainhum

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Search GEO for disease gene expression data for Ainhum.

Pathways for genes affiliated with Ainhum

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Compounds for genes affiliated with Ainhum

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GO Terms for genes affiliated with Ainhum

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Products for genes affiliated with Ainhum

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Sources for Ainhum

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3CDC
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22GTR
23HGMD
24HMDB
25ICD10
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29KEGG
33MeSH
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35MGI
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50PubMed
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56SNOMED-CT via Orphanet
60UMLS
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